-
1
-
-
0015237292
-
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
-
Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature New Biol 1971; 231: 232-5
-
(1971)
Nature New Biol
, vol.231
, pp. 232-235
-
-
Vane, J.R.1
-
2
-
-
0015237275
-
Aspirin selectively inhibits prostaglandin production in human platelets
-
Smith WL, Willis AL. Aspirin selectively inhibits prostaglandin production in human platelets. Nature New Biol 1971; 231: 235-7
-
(1971)
Nature New Biol
, vol.231
, pp. 235-237
-
-
Smith, W.L.1
Willis, A.L.2
-
3
-
-
0015237263
-
Indomethacin and aspirin abolish prostaglandin release from the spleen
-
Ferreira SH, Moncada S, Vane JR. Indomethacin and aspirin abolish prostaglandin release from the spleen. Nature New Biol 1971; 231: 237-9
-
(1971)
Nature New Biol
, vol.231
, pp. 237-239
-
-
Ferreira, S.H.1
Moncada, S.2
Vane, J.R.3
-
4
-
-
0016227738
-
Drugs which inhibit prostaglandin biosynthesis
-
Flower RJ. Drugs which inhibit prostaglandin biosynthesis. Pharmacol Rev 1974; 26: 33-67
-
(1974)
Pharmacol Rev
, vol.26
, pp. 33-67
-
-
Flower, R.J.1
-
6
-
-
0015511847
-
Inhibition of prostaglandin synthase in brain explains the antipyretic activity of paracetamol (4-acetamidophenol)
-
Flower RJ, Vane JR. Inhibition of prostaglandin synthase in brain explains the antipyretic activity of paracetamol (4-acetamidophenol). Nature New Biol 1972; 240: 410-1
-
(1972)
Nature New Biol
, vol.240
, pp. 410-411
-
-
Flower, R.J.1
Vane, J.R.2
-
7
-
-
0018904225
-
Selective inhibition of prostaglandin production in inflammatory exudates and gastric mucosa
-
Whittle BJR, Higgs GA, Eakins KE, et al. Selective inhibition of prostaglandin production in inflammatory exudates and gastric mucosa. Nature New Biol 1980; 284: 271-3
-
(1980)
Nature New Biol
, vol.284
, pp. 271-273
-
-
Whittle, B.J.R.1
Higgs, G.A.2
Eakins, K.E.3
-
8
-
-
0242325380
-
Prostaglandins and the aspirin-like drugs
-
Vane JR. Prostaglandins and the aspirin-like drugs. Hosp Pract 1972; 7: 61-71
-
(1972)
Hosp Pract
, vol.7
, pp. 61-71
-
-
Vane, J.R.1
-
9
-
-
0020039317
-
Evidence for two distinct forms of fatty acid cyclooxygenase in brain
-
Lysz TW, Needleman P. Evidence for two distinct forms of fatty acid cyclooxygenase in brain. J Neurochem 1982; 38: 1111-7
-
(1982)
J Neurochem
, vol.38
, pp. 1111-1117
-
-
Lysz, T.W.1
Needleman, P.2
-
10
-
-
0024381125
-
Comparative analgesic and anti-inflammatory properlies of sodium salicylate and acetylsalicyclic acid (aspirin) in rheumatoid arthritis
-
Preston SJ, Arnold MH, Beller EM, et al. Comparative analgesic and anti-inflammatory properlies of sodium salicylate and acetylsalicyclic acid (aspirin) in rheumatoid arthritis. Br J Pharmacol 1989; 27: 607-11
-
(1989)
Br J Pharmacol
, vol.27
, pp. 607-611
-
-
Preston, S.J.1
Arnold, M.H.2
Beller, E.M.3
-
11
-
-
0024528916
-
The mechanism of action of non-steroidal anti-inflammatory drugs
-
Abramson SB, Weissmann G. The mechanism of action of non-steroidal anti-inflammatory drugs. Arthritis Rheum 1989; 32: 1-9
-
(1989)
Arthritis Rheum
, vol.32
, pp. 1-9
-
-
Abramson, S.B.1
Weissmann, G.2
-
12
-
-
0028018895
-
Non steroidal anti-inflammatory drugs and spinal nociceptive processing
-
McCormack K. Non steroidal anti-inflammatory drugs and spinal nociceptive processing. Pain 1994; 59: 9-43
-
(1994)
Pain
, vol.59
, pp. 9-43
-
-
McCormack, K.1
-
13
-
-
0025005862
-
The induction and suppression of prostaglandin H2 synthusc (cyclooxygenase) in human monocytes
-
Fu JY, Masferrer JL, Seibert K, et al. The induction and suppression of prostaglandin H2 synthusc (cyclooxygenase) in human monocytes. J Biol Chem 1990; 265: 16737-40
-
(1990)
J Biol Chem
, vol.265
, pp. 16737-16740
-
-
Fu, J.Y.1
Masferrer, J.L.2
Seibert, K.3
-
14
-
-
0025187588
-
Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice
-
Masferrer JL, Zweifel BS, Seibert K, et al. Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice. J Clin Invest 1990; 86: 1375-9
-
(1990)
J Clin Invest
, vol.86
, pp. 1375-1379
-
-
Masferrer, J.L.1
Zweifel, B.S.2
Seibert, K.3
-
15
-
-
0001208476
-
Temporal and pharmacological division of fibroblast cyclooxygenase expression into transcriptional and translational phase
-
Raz A, Wyche A, Needlman P. Temporal and pharmacological division of fibroblast cyclooxygenase expression into transcriptional and translational phase. Proc Natl Acad Sci USA 1989; 86: 1657-61
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 1657-1661
-
-
Raz, A.1
Wyche, A.2
Needlman, P.3
-
16
-
-
0028180129
-
Induction of cyclooxygenase-2 by interleukin-1α
-
Ristimäki A, Garfinkel S, Wessendorf J, et al. Induction of cyclooxygenase-2 by interleukin-1α. J Biol Chem 1994; 269: 11769-75
-
(1994)
J Biol Chem
, vol.269
, pp. 11769-11775
-
-
Ristimäki, A.1
Garfinkel, S.2
Wessendorf, J.3
-
17
-
-
0028290632
-
Cloning and characterization of growth factor-inducible cyclooxygenase gene from rat intestinal epithelial cells
-
DuBois RN, Tsujii M, Bishop P, et al. Cloning and characterization of growth factor-inducible cyclooxygenase gene from rat intestinal epithelial cells. Am J Physiol 1994; 266: G822-7
-
(1994)
Am J Physiol
, vol.266
-
-
DuBois, R.N.1
Tsujii, M.2
Bishop, P.3
-
18
-
-
0027451973
-
Transcriptional regulation of the rat proslaglandin endoperoxide synthase 2 gene in granulosa cells
-
Sirois J, Richards JS. Transcriptional regulation of the rat proslaglandin endoperoxide synthase 2 gene in granulosa cells. J Biol Chem 1993; 268: 21931-8
-
(1993)
J Biol Chem
, vol.268
, pp. 21931-21938
-
-
Sirois, J.1
Richards, J.S.2
-
19
-
-
0027469850
-
Expression of the protein product of prostaglandin synthase-2/TIS10 gene in mitogen-slimulated swiss 3T3 cells
-
Kujubu DA, Roddy ST, Fletcher BS, et al. Expression of the protein product of prostaglandin synthase-2/TIS10 gene in mitogen-slimulated swiss 3T3 cells. J Biol Chem 1991; 268: 5425-30
-
(1991)
J Biol Chem
, vol.268
, pp. 5425-5430
-
-
Kujubu, D.A.1
Roddy, S.T.2
Fletcher, B.S.3
-
20
-
-
0025754779
-
Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing
-
Xie W, Chipman JG, Robertson DL, et al. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc Natl Acad Sci USA 1991; 88: 2692-6
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 2692-2696
-
-
Xie, W.1
Chipman, J.G.2
Robertson, D.L.3
-
21
-
-
0026322957
-
A serum- and glucocorticoid-regulated 4-kilobase mRNA encodes a cyclooxygenase-related protein
-
O'Bannion MK, Sadowski HB, Winn V, et al. A serum- and glucocorticoid-regulated 4-kilobase mRNA encodes a cyclooxygenase-related protein. J Biol Chem 1991; 266: 23261-7
-
(1991)
J Biol Chem
, vol.266
, pp. 23261-23267
-
-
O'Bannion, M.K.1
Sadowski, H.B.2
Winn, V.3
-
22
-
-
0027912932
-
PGH synthase isoenzyme selectivity: The potential for safer nonsteroidal anti-inflammatory drugs
-
DeWitt DL, Meade E, Smith WL. PGH synthase isoenzyme selectivity: the potential for safer nonsteroidal anti-inflammatory drugs. Am J Med 1993; 95: 40S-4S
-
(1993)
Am J Med
, vol.95
-
-
DeWitt, D.L.1
Meade, E.2
Smith, W.L.3
-
23
-
-
0028044609
-
Towards a better aspirin
-
Vane JR. Towards a better aspirin. Nature New Biol 1994; 367: 215-6
-
(1994)
Nature New Biol
, vol.367
, pp. 215-216
-
-
Vane, J.R.1
-
24
-
-
0028032723
-
COX-1 and COX-2: Toward the development of more selective NSAIDs
-
Battistini B, Botting R, Bakhle YS. COX-1 and COX-2: Toward the development of more selective NSAIDs. Drug News Perpect 1994; 7: 501-11
-
(1994)
Drug News Perpect
, vol.7
, pp. 501-511
-
-
Battistini, B.1
Botting, R.2
Bakhle, Y.S.3
-
25
-
-
0025728865
-
Prostaglandin endoperoxide synthase: Structure and catalysis
-
Smith WL, Marnett LJ. Prostaglandin endoperoxide synthase: structure and catalysis. Biochim Biophys Acta 1991; 1083: 1-17
-
(1991)
Biochim Biophys Acta
, vol.1083
, pp. 1-17
-
-
Smith, W.L.1
Marnett, L.J.2
-
26
-
-
0029975669
-
Prostaglandin endoperoxide H synthases-1 and -2
-
Smith WL, DeWitt DL. Prostaglandin endoperoxide H synthases-1 and -2. Adv Immunol 1996; 62: 167-215
-
(1996)
Adv Immunol
, vol.62
, pp. 167-215
-
-
Smith, W.L.1
DeWitt, D.L.2
-
27
-
-
0028359876
-
Interaction between peroxidase and cyclooxygenase activities in prostaglandin-endoperoxide synthase
-
Kulmacz R J, Pendleton RB, Lands WEM. Interaction between peroxidase and cyclooxygenase activities in prostaglandin-endoperoxide synthase. Biochemistry 1994; 33: 5428-39
-
(1994)
Biochemistry
, vol.33
, pp. 5428-5439
-
-
Kulmacz, R.J.1
Pendleton, R.B.2
Lands, W.E.M.3
-
28
-
-
0026588961
-
Mitogen-inducible prostaglandin G/H synthase: A new target for nonsteroidal anti-inflammatory drugs
-
Xie W, Robertson DL, Simmons DL. Mitogen-inducible prostaglandin G/H synthase: a new target for nonsteroidal anti-inflammatory drugs. Drug Dev Res 1992; 25: 249-65
-
(1992)
Drug Dev Res
, vol.25
, pp. 249-265
-
-
Xie, W.1
Robertson, D.L.2
Simmons, D.L.3
-
29
-
-
0028110531
-
Purification and characterization of recombinant human cyclooxygenase-2
-
Percival MD, Ouellet M, Vincent CJ, et al. Purification and characterization of recombinant human cyclooxygenase-2. Arch Biochem Biophys 1994; 315: 111-8
-
(1994)
Arch Biochem Biophys
, vol.315
, pp. 111-118
-
-
Percival, M.D.1
Ouellet, M.2
Vincent, C.J.3
-
30
-
-
0027480087
-
Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isoenzyme by aspirin and other non-steroidal anti-inflammatory drugs
-
Meade EA, Smith WL, DeWitt DL. Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isoenzyme by aspirin and other non-steroidal anti-inflammatory drugs. J Biol Chem 1993; 268: 6610-4
-
(1993)
J Biol Chem
, vol.268
, pp. 6610-6614
-
-
Meade, E.A.1
Smith, W.L.2
DeWitt, D.L.3
-
31
-
-
0028959950
-
Regulation of prostaglandin endoperoxide synthase (cyclooxygenase) isozyme expression
-
Goppelt-Struebe M. Regulation of prostaglandin endoperoxide synthase (cyclooxygenase) isozyme expression. Prostaglandins Leukol Essent Fatty Acids 1995; 52: 213-22
-
(1995)
Prostaglandins Leukol Essent Fatty Acids
, vol.52
, pp. 213-222
-
-
Goppelt-Struebe, M.1
-
32
-
-
0030049390
-
Prostaglandin synthase 2
-
Herschman HR. Prostaglandin synthase 2. Biochim Biophys Acta 1996; 1299: 125-40
-
(1996)
Biochim Biophys Acta
, vol.1299
, pp. 125-140
-
-
Herschman, H.R.1
-
33
-
-
0029924110
-
Prostaglandin endoperoxide synthase: Why two isoforms?
-
Williams CS, DuBois RN. Prostaglandin endoperoxide synthase: why two isoforms? Am J Physiol 1996; 270: G393-400
-
(1996)
Am J Physiol
, vol.270
-
-
Williams, C.S.1
DuBois, R.N.2
-
34
-
-
0028147767
-
Structure of the human cyclo-oxygenase-2 gene
-
Appleby SB, Ristimaki A, Neilson K, et al. Structure of the human cyclo-oxygenase-2 gene. Biochem J 1994; 302: 723-7
-
(1994)
Biochem J
, vol.302
, pp. 723-727
-
-
Appleby, S.B.1
Ristimaki, A.2
Neilson, K.3
-
35
-
-
0028226265
-
Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2
-
Kosaka T, Miyata A, Ihara H, et al. Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2. Eur J Biochem 1994; 221: 889-97
-
(1994)
Eur J Biochem
, vol.221
, pp. 889-897
-
-
Kosaka, T.1
Miyata, A.2
Ihara, H.3
-
36
-
-
0027230212
-
Interleukin-1 differentially modulates chondrocyte expression of cyclooxygenase-2 and phospholipase A2
-
Lyons-Giordano B, Pratta MA, Galbraith W, et al. Interleukin-1 differentially modulates chondrocyte expression of cyclooxygenase-2 and phospholipase A2. Exp Cell Res 1993; 206: 58-62
-
(1993)
Exp Cell Res
, vol.206
, pp. 58-62
-
-
Lyons-Giordano, B.1
Pratta, M.A.2
Galbraith, W.3
-
37
-
-
0027967245
-
IL-1β stabilizes COX II mRNA in renal mesangial cells: Role of 3′-untranslated region
-
Srivastava KS, Tetsuka T, Daphna-Iken D, et al. IL-1β stabilizes COX II mRNA in renal mesangial cells: role of 3′-untranslated region. Am J Physiol 1994; 267: F504-8
-
(1994)
Am J Physiol
, vol.267
-
-
Srivastava, K.S.1
Tetsuka, T.2
Daphna-Iken, D.3
-
38
-
-
0027369679
-
Serum and glucocorticoid regulation of gene transcription and expression of the prostaglandin H synthase-1 and prostaglandin H synthase-2 isozymes
-
DeWitt DL, Meade E. Serum and glucocorticoid regulation of gene transcription and expression of the prostaglandin H synthase-1 and prostaglandin H synthase-2 isozymes. Arch Biochem Biophys 1993; 306: 94-102
-
(1993)
Arch Biochem Biophys
, vol.306
, pp. 94-102
-
-
DeWitt, D.L.1
Meade, E.2
-
39
-
-
0029809863
-
Down-regulation of cytokine-induced cyclo-oxygenase-2 transcript isoforms by dexamethasone: Evidence for post-transcriptional regulation
-
Ristimäki A, Narko K, Hla T. Down-regulation of cytokine-induced cyclo-oxygenase-2 transcript isoforms by dexamethasone: evidence for post-transcriptional regulation. Biochem J 1996; 318: 325-31
-
(1996)
Biochem J
, vol.318
, pp. 325-331
-
-
Ristimäki, A.1
Narko, K.2
Hla, T.3
-
40
-
-
0027462106
-
Differentiation-associated expression of prostaglandin G/H synthase in monocytic cells
-
Hoff T, DeWitt DL, Kaever V, et al. Differentiation-associated expression of prostaglandin G/H synthase in monocytic cells. FEBS Lett 1993; 320: 38-42
-
(1993)
FEBS Lett
, vol.320
, pp. 38-42
-
-
Hoff, T.1
DeWitt, D.L.2
Kaever, V.3
-
41
-
-
0028170074
-
v-src induction of the TIS 10/PGS2 prostaglandin synthase gene is mediated by an ATF/CRE transcription response element
-
Xie W, Fletcher BS, Andersen RD, et al. v-src induction of the TIS 10/PGS2 prostaglandin synthase gene is mediated by an ATF/CRE transcription response element. Mol Cell Biol 1994; 14: 6531-9
-
(1994)
Mol Cell Biol
, vol.14
, pp. 6531-6539
-
-
Xie, W.1
Fletcher, B.S.2
Andersen, R.D.3
-
42
-
-
0028069896
-
The cyclic AMP response element plays an essential role in the expression of the human prostaglandin-endoperoxide synthase-2 gene in differentiated U937 monocytic cells
-
Inoue H, Nanayama T, Hara S, et al. The cyclic AMP response element plays an essential role in the expression of the human prostaglandin-endoperoxide synthase-2 gene in differentiated U937 monocytic cells. FEBS Lett 1994; 350: 51-4
-
(1994)
FEBS Lett
, vol.350
, pp. 51-54
-
-
Inoue, H.1
Nanayama, T.2
Hara, S.3
-
43
-
-
0028183018
-
Classification of prostanoid receptors: Properties, distribution, and structure of the receptors and their subtypes
-
Coleman RA, Smith WL, Narumiya S. Classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes. Pharmacol Rev 1994; 46: 205-29
-
(1994)
Pharmacol Rev
, vol.46
, pp. 205-229
-
-
Coleman, R.A.1
Smith, W.L.2
Narumiya, S.3
-
44
-
-
0027162479
-
Structural determination and promoter analysis of the chicken mitogen-inducible proslaglandin G/H synthase gene and genetic mapping of the murine homologue
-
Xie W, Merrill JR, Bradshaw WS, et al. Structural determination and promoter analysis of the chicken mitogen-inducible proslaglandin G/H synthase gene and genetic mapping of the murine homologue. Arch Biochem Biophys 1993; 300: 247-52
-
(1993)
Arch Biochem Biophys
, vol.300
, pp. 247-252
-
-
Xie, W.1
Merrill, J.R.2
Bradshaw, W.S.3
-
45
-
-
0028879819
-
Role of transcriptional activation of IkBα in mediation of immunosuppression by glucocorticoids
-
Scheinman RI, Cogswell PC, Lofquist AK, et al. Role of transcriptional activation of IkBα in mediation of immunosuppression by glucocorticoids. Science 1995; 270: 283-6
-
(1995)
Science
, vol.270
, pp. 283-286
-
-
Scheinman, R.I.1
Cogswell, P.C.2
Lofquist, A.K.3
-
46
-
-
0028867899
-
Immunosuppression by glucocorticoids: Inhibition of NF-kB activity through induction of IkB synthesis
-
Auphan N, DiDonato JA, Rosette C, et al. Immunosuppression by glucocorticoids: inhibition of NF-kB activity through induction of IkB synthesis. Science 1995; 270: 286-9
-
(1995)
Science
, vol.270
, pp. 286-289
-
-
Auphan, N.1
DiDonato, J.A.2
Rosette, C.3
-
47
-
-
0027141004
-
Cloning two isoforms of rat cyclooxygenase: Differential regulation of their expression
-
Feng L, Sun W, Xia Y, et al. Cloning two isoforms of rat cyclooxygenase: differential regulation of their expression. Arch Biochem Biophys 1993; 307: 169-77
-
(1993)
Arch Biochem Biophys
, vol.307
, pp. 169-177
-
-
Feng, L.1
Sun, W.2
Xia, Y.3
-
48
-
-
0027293391
-
Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues
-
O'Neill GP, Ford-Hutchinson AW. Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues. FEBS Lett 1993; 330: 156-60
-
(1993)
FEBS Lett
, vol.330
, pp. 156-160
-
-
O'Neill, G.P.1
Ford-Hutchinson, A.W.2
-
49
-
-
0027944075
-
Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain
-
Seibert K, Zhang Y, Leahy K, et al. Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain. Proc Natl Acad Sci USA 1994; 91: 12013-7
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 12013-12017
-
-
Seibert, K.1
Zhang, Y.2
Leahy, K.3
-
50
-
-
0027290813
-
Expression of a mitogen-inducible cyclooxygenase in brain neuron: Regulation by synaptic activity and glucocorticoids
-
Yamagata K, Anderasson KI, Kaufmann WE, et al. Expression of a mitogen-inducible cyclooxygenase in brain neuron: regulation by synaptic activity and glucocorticoids. Neuron 1993; 11: 371-86
-
(1993)
Neuron
, vol.11
, pp. 371-386
-
-
Yamagata, K.1
Anderasson, K.I.2
Kaufmann, W.E.3
-
51
-
-
0029028590
-
Immunocytochemical localization of cyclooxygenase-1 and -2 in the rat stomach
-
Iseki S. Immunocytochemical localization of cyclooxygenase-1 and -2 in the rat stomach. Histochem J 1995; 27: 323-8
-
(1995)
Histochem J
, vol.27
, pp. 323-328
-
-
Iseki, S.1
-
52
-
-
0029866955
-
Expression of inducible cyclooxygenase mRNA in the mouse brain after systemic administration of bacterial lipopolysaccharide
-
Breder CD, Saper CB. Expression of inducible cyclooxygenase mRNA in the mouse brain after systemic administration of bacterial lipopolysaccharide. Brain Res 1996; 713: 64-9
-
(1996)
Brain Res
, vol.713
, pp. 64-69
-
-
Breder, C.D.1
Saper, C.B.2
-
53
-
-
0028902109
-
Characterization of inducible cyclooxygenase in the rat brain
-
Breder CD, DeWitt DL, Kraig RP. Characterization of inducible cyclooxygenase in the rat brain. J Comp Neurol 1995; 355: 296-315
-
(1995)
J Comp Neurol
, vol.355
, pp. 296-315
-
-
Breder, C.D.1
DeWitt, D.L.2
Kraig, R.P.3
-
54
-
-
0028903129
-
Mediation of inflammation by cyclooxygenase-2
-
Seibert K, Masferrer JL, Zhang Y, et al. Mediation of inflammation by cyclooxygenase-2. Agents Actions 1995; 46 Suppl.: 41-50
-
(1995)
Agents Actions
, vol.46
, Issue.SUPPL.
, pp. 41-50
-
-
Seibert, K.1
Masferrer, J.L.2
Zhang, Y.3
-
55
-
-
0017684302
-
Immunochemistry of prostaglandin endoperoxide forming cyclooxygenases: The detection of cyclooxygenases in rat, rabbit, and guinea pig kidneys by immunofluorescence
-
Smith WL, Wilkin GP. Immunochemistry of prostaglandin endoperoxide forming cyclooxygenases: the detection of cyclooxygenases in rat, rabbit, and guinea pig kidneys by immunofluorescence. Prostaglandins 1977; 13: 873-92
-
(1977)
Prostaglandins
, vol.13
, pp. 873-892
-
-
Smith, W.L.1
Wilkin, G.P.2
-
56
-
-
0028034970
-
Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction
-
Harris RC, McKanna JA, Akai Y, et al. Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction. J Clin Invest 1994; 94: 2504-10
-
(1994)
J Clin Invest
, vol.94
, pp. 2504-2510
-
-
Harris, R.C.1
McKanna, J.A.2
Akai, Y.3
-
57
-
-
0028969527
-
Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2
-
Morita I, Schinder M, Regier MK, et al. Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2. J Biol Chem 1995; 270: 10902-8
-
(1995)
J Biol Chem
, vol.270
, pp. 10902-10908
-
-
Morita, I.1
Schinder, M.2
Regier, M.K.3
-
58
-
-
0028802627
-
Differential activation of peroxisome proliferator-activated receptors by eicosanoids
-
Yu K, Bayowa Y, Kallen CB, et al. Differential activation of peroxisome proliferator-activated receptors by eicosanoids. J Biol Chem 1995; 270: 23975-83
-
(1995)
J Biol Chem
, vol.270
, pp. 23975-23983
-
-
Yu, K.1
Bayowa, Y.2
Kallen, C.B.3
-
59
-
-
0028972026
-
A prostaglandin J2 metabolite binds peroxisome proliferator-actived receptor γ and promotes adipocyte differentiation
-
Kliewer SA, Lenhard JM, Willson TM, et al. A prostaglandin J2 metabolite binds peroxisome proliferator-actived receptor γ and promotes adipocyte differentiation. Cell 1995; 83: 813-9
-
(1995)
Cell
, vol.83
, pp. 813-819
-
-
Kliewer, S.A.1
Lenhard, J.M.2
Willson, T.M.3
-
60
-
-
0027998628
-
Prostaglandin endoperoxide synthase-1 and -2 couple to different transmembrane stimuli to generate prostaglandin D2 in mouse bone marrow-derived mast cells
-
Murakami M, Matsumoto R, Austen KF, et al. Prostaglandin endoperoxide synthase-1 and -2 couple to different transmembrane stimuli to generate prostaglandin D2 in mouse bone marrow-derived mast cells. J Biol Chem 1994; 269: 22269-75
-
(1994)
J Biol Chem
, vol.269
, pp. 22269-22275
-
-
Murakami, M.1
Matsumoto, R.2
Austen, K.F.3
-
61
-
-
0029004082
-
Prostaglandin synthase 1 and prostaglandin synthase 2 both participate in activation-induced prostaglandin D2 production in mast cell
-
Kawata R, Reddy ST, Wolner B, et al. Prostaglandin synthase 1 and prostaglandin synthase 2 both participate in activation-induced prostaglandin D2 production in mast cell. J Immunol 1995; 155: 818-25
-
(1995)
J Immunol
, vol.155
, pp. 818-825
-
-
Kawata, R.1
Reddy, S.T.2
Wolner, B.3
-
62
-
-
0029664422
-
Cyclooxygenases-1 and -2 of endothelial cells utilize exogenous or endogenous arachidonic acid for transcellular production of thromboxane
-
Karim S, Habib A, Levy-Toledano S, et al. Cyclooxygenases-1 and -2 of endothelial cells utilize exogenous or endogenous arachidonic acid for transcellular production of thromboxane. J Biol Chem 1996; 271: 12042-8
-
(1996)
J Biol Chem
, vol.271
, pp. 12042-12048
-
-
Karim, S.1
Habib, A.2
Levy-Toledano, S.3
-
63
-
-
0028843881
-
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
-
Langenbach R, Morham SG, Tiano HF, et al. Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. Cell 1995; 83: 483-92
-
(1995)
Cell
, vol.83
, pp. 483-492
-
-
Langenbach, R.1
Morham, S.G.2
Tiano, H.F.3
-
64
-
-
0028807498
-
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
-
Morham SG, Langenbach R, Loftin CD, et al. Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse. Cell 1995; 83: 473-82
-
(1995)
Cell
, vol.83
, pp. 473-482
-
-
Morham, S.G.1
Langenbach, R.2
Loftin, C.D.3
-
65
-
-
0028818913
-
Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II
-
Dinchuk JE, Car BD, Focht RJ, et al. Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II. Nature 1995; 378: 406-9
-
(1995)
Nature
, vol.378
, pp. 406-409
-
-
Dinchuk, J.E.1
Car, B.D.2
Focht, R.J.3
-
66
-
-
0028009093
-
The x-ray crystal structure of the membrane protein prostaglandin H2 synthase-1
-
Picot D, Loll PJ, Garavito M. The x-ray crystal structure of the membrane protein prostaglandin H2 synthase-1. Nature 1994; 367: 243-9
-
(1994)
Nature
, vol.367
, pp. 243-249
-
-
Picot, D.1
Loll, P.J.2
Garavito, M.3
-
67
-
-
0028430187
-
Prostaglandin synthase: At the heart of the matter
-
Blake C. Prostaglandin synthase: at the heart of the matter. Curr Biol 1994; 4: 452-4
-
(1994)
Curr Biol
, vol.4
, pp. 452-454
-
-
Blake, C.1
-
68
-
-
0025248570
-
The aspirin and heme-binding sites of ovine and murine prostaglandin endoperoxydes synthases
-
DeWitt DL, El-Harith EA, Kraemer SA, et al. The aspirin and heme-binding sites of ovine and murine prostaglandin endoperoxydes synthases. J Biol Chem 1990; 265: 5192-8
-
(1990)
J Biol Chem
, vol.265
, pp. 5192-5198
-
-
Dewitt, D.L.1
El-Harith, E.A.2
Kraemer, S.A.3
-
69
-
-
0028938334
-
Spectroscopic evidence for reaction of prostaglandin H synthase-1 tyrosyl radical with arachidonic acid
-
Tsai AL, Kulmacz RJ, Palmer G. Spectroscopic evidence for reaction of prostaglandin H synthase-1 tyrosyl radical with arachidonic acid. J Biol Chem 1995; 270: 10503-8
-
(1995)
J Biol Chem
, vol.270
, pp. 10503-10508
-
-
Tsai, A.L.1
Kulmacz, R.J.2
Palmer, G.3
-
70
-
-
0029056992
-
The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase
-
Loll PJ, Picot D, Garavito M. The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase. Nature Struct Biol 1995; 2: 637-43
-
(1995)
Nature Struct Biol
, vol.2
, pp. 637-643
-
-
Loll, P.J.1
Picot, D.2
Garavito, M.3
-
71
-
-
0024363551
-
Topography of prostaglandin H synthase
-
Kulmacz RJ. Topography of prostaglandin H synthase. J Biol Chem 1989; 264: 14136-44
-
(1989)
J Biol Chem
, vol.264
, pp. 14136-14144
-
-
Kulmacz, R.J.1
-
72
-
-
0030010696
-
Synthesis and use of iodinated nonsteroidal anti-inflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site
-
Loll PJ, Picot D, Ekabo O, et al. Synthesis and use of iodinated nonsteroidal anti-inflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site. Biochemistry 1996; 35: 7330-40
-
(1996)
Biochemistry
, vol.35
, pp. 7330-7340
-
-
Loll, P.J.1
Picot, D.2
Ekabo, O.3
-
73
-
-
0028783912
-
Arginine 120 of prostaglandin G/H synthase-1 is required for the inhibition by nonsteroidal anti-inflammatory drugs containing a carboxylic acid moiety
-
Mancini JA, Riendeau D, Falgueyret JP, et al. Arginine 120 of prostaglandin G/H synthase-1 is required for the inhibition by nonsteroidal anti-inflammatory drugs containing a carboxylic acid moiety. J Biol Chem 1995; 270: 29372-7
-
(1995)
J Biol Chem
, vol.270
, pp. 29372-29377
-
-
Mancini, J.A.1
Riendeau, D.2
Falgueyret, J.P.3
-
74
-
-
0030068054
-
Involvement of Arginine 120. Glutamate 524, and Tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1
-
Bhattacharyya DK, Lecomte M, Ricke CJ, et al. Involvement of Arginine 120. Glutamate 524, and Tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1. J Biol Chem 1996; 271: 2179-84
-
(1996)
J Biol Chem
, vol.271
, pp. 2179-2184
-
-
Bhattacharyya, D.K.1
Lecomte, M.2
Ricke, C.J.3
-
75
-
-
0025856636
-
Nonsteroidal anti-inflammatory drugs - Differences and similarities
-
Brooks PM, Day RO. Nonsteroidal anti-inflammatory drugs - differences and similarities. N Engl J Med 1991; 324: 1716-25
-
(1991)
N Engl J Med
, vol.324
, pp. 1716-1725
-
-
Brooks, P.M.1
Day, R.O.2
-
76
-
-
0029911267
-
Flexibility of the NSAID binding site in the structure of human cyclo-oxygenase-2
-
Luong C, Miller A, Barnett J, et al. Flexibility of the NSAID binding site in the structure of human cyclo-oxygenase-2. Nature Struct Biol 1996; 3: 927-33
-
(1996)
Nature Struct Biol
, vol.3
, pp. 927-933
-
-
Luong, C.1
Miller, A.2
Barnett, J.3
-
77
-
-
0027146692
-
Selectivity of non steroidal anti-inflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase
-
Mitchell JA, Akarasereenont P, Thiemermann C, et al. Selectivity of non steroidal anti-inflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci USA 1993; 90: 11693-7
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11693-11697
-
-
Mitchell, J.A.1
Akarasereenont, P.2
Thiemermann, C.3
-
78
-
-
0027986841
-
Differential inhibition of human prostaglandin endoperoxide H synthase-1 and -2 by nonsteroidal anti-inflammatory drugs
-
Laneuville O, Breuer DK, DeWitt DL, et al. Differential inhibition of human prostaglandin endoperoxide H synthase-1 and -2 by nonsteroidal anti-inflammatory drugs. J Pharmacol Exp Ther 1994; 271: 927-34
-
(1994)
J Pharmacol Exp Ther
, vol.271
, pp. 927-934
-
-
Laneuville, O.1
Breuer, D.K.2
DeWitt, D.L.3
-
79
-
-
0028339780
-
Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin
-
Lecomte M, Laneuville O, Chuan J, et al. Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin. J Biol Chem 1994; 269: 13207-15
-
(1994)
J Biol Chem
, vol.269
, pp. 13207-13215
-
-
Lecomte, M.1
Laneuville, O.2
Chuan, J.3
-
80
-
-
0028295135
-
Mutation of serine 516 in human prostaglandin G/H synthase-2 to methionine or aspirin acetylation of this residue stimulates 15-R-HETE synthesis
-
Mancini JA, O'Neill GP, Bayly C, et al. Mutation of serine 516 in human prostaglandin G/H synthase-2 to methionine or aspirin acetylation of this residue stimulates 15-R-HETE synthesis. FEBS Lett 1994; 342: 33-7
-
(1994)
FEBS Lett
, vol.342
, pp. 33-37
-
-
Mancini, J.A.1
O'Neill, G.P.2
Bayly, C.3
-
81
-
-
0029047415
-
Aspirin - now we can see it
-
Allen KN. Aspirin - now we can see it. Nature Med 1995; 1: 882-3
-
(1995)
Nature Med
, vol.1
, pp. 882-883
-
-
Allen, K.N.1
-
82
-
-
0029093282
-
Comparison of recombinant cyclooxygenase-2 to native isoforms: Aspirin labeling of the active site
-
Wennogle LP, Liang H, Quintavalla JC, et al. Comparison of recombinant cyclooxygenase-2 to native isoforms: aspirin labeling of the active site. FEBS Lett 1995; 371: 315-20
-
(1995)
FEBS Lett
, vol.371
, pp. 315-320
-
-
Wennogle, L.P.1
Liang, H.2
Quintavalla, J.C.3
-
83
-
-
0006225524
-
The x-ray structures of complexes of cyclooxygenase-1 and inhibitors
-
Garavito RM, Picot D, Loll PL. The x-ray structures of complexes of cyclooxygenase-1 and inhibitors. Med Chem Res 1995; 5: 375-83
-
(1995)
Med Chem Res
, vol.5
, pp. 375-383
-
-
Garavito, R.M.1
Picot, D.2
Loll, P.L.3
-
84
-
-
0029899186
-
A single aminoacid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors
-
Gierse JK, McDonald JJ, Hauser SD, et al. A single aminoacid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors. J Biol Chem 1996; 271: 15810-4
-
(1996)
J Biol Chem
, vol.271
, pp. 15810-15814
-
-
Gierse, J.K.1
McDonald, J.J.2
Hauser, S.D.3
-
85
-
-
0000151210
-
Structural requirements for time-dependent inhibition of prostanglandin biosynthesis by anti-inflammatory drugs
-
Rome LH, Lands WEM. Structural requirements for time-dependent inhibition of prostanglandin biosynthesis by anti-inflammatory drugs. Proc Natl Acad Sci USA 1975; 72: 4863-5
-
(1975)
Proc Natl Acad Sci USA
, vol.72
, pp. 4863-4865
-
-
Rome, L.H.1
Lands, W.E.M.2
-
86
-
-
0022382640
-
Stoichiometry and kinetics of the interaction of prostaglandin H synthase with anti-inflammatory agents
-
Kulmacz RJ, Lands WEM. Stoichiometry and kinetics of the interaction of prostaglandin H synthase with anti-inflammatory agents. J Biol Chem 1985; 260: 12572-8
-
(1985)
J Biol Chem
, vol.260
, pp. 12572-12578
-
-
Kulmacz, R.J.1
Lands, W.E.M.2
-
87
-
-
0028139275
-
Mechanism of selective inhibition of the inducible isoform of prostaglandin G/H synthase
-
Copeland RA, Williams JM, Giannaras J, et al. Mechanism of selective inhibition of the inducible isoform of prostaglandin G/H synthase. Proc Natl Acad Sci USA 1994; 91: 11202-6
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 11202-11206
-
-
Copeland, R.A.1
Williams, J.M.2
Giannaras, J.3
-
88
-
-
0028831977
-
Effect of inhibitor time-dependency on selectivity towards cyclooxygenase isoforms
-
Quellet M, Percival MD. Effect of inhibitor time-dependency on selectivity towards cyclooxygenase isoforms. Biochem J 1995; 306: 247-51
-
(1995)
Biochem J
, vol.306
, pp. 247-251
-
-
Quellet, M.1
Percival, M.D.2
-
89
-
-
0000486214
-
The differential susceptibility of prostaglandin endoperoxyde H synthase-1 and -2 to nonsteroidal anti-inflammatory drugs: Aspirin derivatives as selective inhibitors
-
DeWitt DL, Bhattacharyya D, Lecomte M, et al. The differential susceptibility of prostaglandin endoperoxyde H synthase-1 and -2 to nonsteroidal anti-inflammatory drugs: aspirin derivatives as selective inhibitors. Med Chem Res 1995; 5: 325-43
-
(1995)
Med Chem Res
, vol.5
, pp. 325-343
-
-
DeWitt, D.L.1
Bhattacharyya, D.2
Lecomte, M.3
-
90
-
-
0028793984
-
Effect of nimesulide action time dependence on selectivity towards prostaglandin G/H synthase / cyclooxygenase activity
-
Vago T, Bevilacqua M, Norbiato G. Effect of nimesulide action time dependence on selectivity towards prostaglandin G/H synthase / cyclooxygenase activity. Arzneimittel Forschung 1995; 45: 1096-8
-
(1995)
Arzneimittel Forschung
, vol.45
, pp. 1096-1098
-
-
Vago, T.1
Bevilacqua, M.2
Norbiato, G.3
-
91
-
-
0028967850
-
Selective inhibition of prostaglandin endoperoxide synthase-1 (cyclooxygenase-1) by valerylsalicylic acid
-
Bhattacharyya DK, Lecomte M, Dunn J, et al. Selective inhibition of prostaglandin endoperoxide synthase-1 (cyclooxygenase-1) by valerylsalicylic acid. Arch Biochem Biophys 1995; 317: 19-24
-
(1995)
Arch Biochem Biophys
, vol.317
, pp. 19-24
-
-
Bhattacharyya, D.K.1
Lecomte, M.2
Dunn, J.3
-
92
-
-
0028089109
-
NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase / cyclooxygenase (COX-2) activity in vitro
-
Futaki N, Takahashi S, Yokoyama M, et al. NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase / cyclooxygenase (COX-2) activity in vitro. Prostaglandins 1994; 47: 55-9
-
(1994)
Prostaglandins
, vol.47
, pp. 55-59
-
-
Futaki, N.1
Takahashi, S.2
Yokoyama, M.3
-
93
-
-
0027992733
-
Purification, characterization and selective inhibition of human prostaglandin G/H Synthase 1 and 2 expressed in the baculovirus system
-
Barnett J, Chow J, Ives D, et al. Purification, characterization and selective inhibition of human prostaglandin G/H Synthase 1 and 2 expressed in the baculovirus system. Biochim Biophys Acta 1994; 1209: 130-9
-
(1994)
Biochim Biophys Acta
, vol.1209
, pp. 130-139
-
-
Barnett, J.1
Chow, J.2
Ives, D.3
-
94
-
-
0028123502
-
Overexpression of human prostaglandin G/H synthase-1 and -2 by recombinant vaccina virus. Inhibition by nonsteroidal anti-inflammatory drugs and biosynthesis of 15-hydroxyeicosatetraenoic acid
-
O'Neill GP, Mancini JA, Kargman S, et al. Overexpression of human prostaglandin G/H synthase-1 and -2 by recombinant vaccina virus. Inhibition by nonsteroidal anti-inflammatory drugs and biosynthesis of 15-hydroxyeicosatetraenoic acid. Mol Pharmacol 1994; 45: 245-54
-
(1994)
Mol Pharmacol
, vol.45
, pp. 245-254
-
-
O'Neill, G.P.1
Mancini, J.A.2
Kargman, S.3
-
95
-
-
0029088821
-
Etodolac selectively inhibits human prostaglandin G/H synthase 2 (PGHS-2) versus human PGHS-1
-
Glaser K, Sung M-L, O'Neill K, et al. Etodolac selectively inhibits human prostaglandin G/H synthase 2 (PGHS-2) versus human PGHS-1. Eur J Pharmacol 1995; 281: 107-11
-
(1995)
Eur J Pharmacol
, vol.281
, pp. 107-111
-
-
Glaser, K.1
Sung, M.-L.2
O'Neill, K.3
-
96
-
-
0028830109
-
Expression and selective inhibition of the constitutive and inducible of human cyclooxygenase
-
Gierse JK, Hauser SD, Creely DP, et al. Expression and selective inhibition of the constitutive and inducible of human cyclooxygenase. Biochem J 1995; 305: 479-84
-
(1995)
Biochem J
, vol.305
, pp. 479-484
-
-
Gierse, J.K.1
Hauser, S.D.2
Creely, D.P.3
-
97
-
-
0030030129
-
Meloxicam: Influence on arachidonic acid metabolism: part 1. in vitro findings
-
Engelhardt G, Bögel R, Schnitzler C, et al. Meloxicam: influence on arachidonic acid metabolism: part 1. In vitro findings. Biochem Pharmacol 1996; 51: 21-8
-
(1996)
Biochem Pharmacol
, vol.51
, pp. 21-28
-
-
Engelhardt, G.1
Bögel, R.2
Schnitzler, C.3
-
98
-
-
0029033219
-
Pharmacology of selective cyclooxygenase-2 inhibitor, L-745,337: A novel nonsteroidal anti-inflammatory agent with an ulcerogenic sparing effect in rat and non human primate stomach
-
Chan CC, Boyce S, Bribeau C, et al. Pharmacology of selective cyclooxygenase-2 inhibitor, L-745,337: a novel nonsteroidal anti-inflammatory agent with an ulcerogenic sparing effect in rat and non human primate stomach. J Pharmacol Exp Ther 1995; 274: 1531-7
-
(1995)
J Pharmacol Exp Ther
, vol.274
, pp. 1531-1537
-
-
Chan, C.C.1
Boyce, S.2
Bribeau, C.3
-
100
-
-
0029882063
-
Selective inhibition of human cyclooxygenase-2 by meloxicum
-
Churchill L, Graham AG, Shih CK, et al. Selective inhibition of human cyclooxygenase-2 by meloxicum. Inflammopharmacology 1996; 4: 125-35
-
(1996)
Inflammopharmacology
, vol.4
, pp. 125-135
-
-
Churchill, L.1
Graham, A.G.2
Shih, C.K.3
-
101
-
-
0030022032
-
A human whole blood assay for clinical evaluation of biological efficacy of cyclooxygenase inhibitors
-
Brideau C, Kargman S, Liu S, et al. A human whole blood assay for clinical evaluation of biological efficacy of cyclooxygenase inhibitors. Inflamm Res 1996; 45: 68-74
-
(1996)
Inflamm Res
, vol.45
, pp. 68-74
-
-
Brideau, C.1
Kargman, S.2
Liu, S.3
-
102
-
-
0027940487
-
Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases
-
Patrignani P, Panara MR, Greco A, et al. Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases. J Pharmacol Exp Ther 1994; 271: 1705-12
-
(1994)
J Pharmacol Exp Ther
, vol.271
, pp. 1705-1712
-
-
Patrignani, P.1
Panara, M.R.2
Greco, A.3
-
103
-
-
0028806251
-
Effects of the novel anti-inflammatory compounds, N-[2-(cyclohexyloxy)-4-nitrophenyl] methanesulphonamide (NS-398) and 5-methanesulphonamido - 6 - (2,4 - difluorothiophenyl) - 1 - indanone (L-745,337), on the cyclo-oxygenase activity of human blood prostaglandin endoperoxide synthase
-
Panara MR, Greco A, Santini G, et al. Effects of the novel anti-inflammatory compounds, N-[2-(cyclohexyloxy)-4-nitrophenyl] methanesulphonamide (NS-398) and 5-methanesulphonamido - 6 - (2,4 - difluorothiophenyl) - 1 - indanone (L-745,337), on the cyclo-oxygenase activity of human blood prostaglandin endoperoxide synthase. Br J Pharmacol 1995; 116: 2429-34
-
(1995)
Br J Pharmacol
, vol.116
, pp. 2429-2434
-
-
Panara, M.R.1
Greco, A.2
Santini, G.3
-
105
-
-
0029029296
-
Inhibition of constitutive and inducible cyclooxygenase activity in human platelets and mononuclear cells by NSAIDs and COX 2 inhibitors
-
Grossman CJ, Wiseman J, Lucas LS, et al. Inhibition of constitutive and inducible cyclooxygenase activity in human platelets and mononuclear cells by NSAIDs and COX 2 inhibitors, Inflamm Res 1995; 44: 253-57
-
(1995)
Inflamm Res
, vol.44
, pp. 253-257
-
-
Grossman, C.J.1
Wiseman, J.2
Lucas, L.S.3
-
106
-
-
0029145880
-
NSAIDs, COX-2 inhibitors, and the gut
-
Hayllar J, Bjarnason I. NSAIDs, COX-2 inhibitors, and the gut. Lancet 1995; 346: 521-2
-
(1995)
Lancet
, vol.346
, pp. 521-522
-
-
Hayllar, J.1
Bjarnason, I.2
-
107
-
-
0029650018
-
NSAIDs, COX-2 inhibitors, and the gut
-
Vane JR. NSAIDs, COX-2 inhibitors, and the gut [letter]. Lancet 1995; 346: 521-2
-
(1995)
Lancet
, vol.346
, pp. 521-522
-
-
Vane, J.R.1
-
108
-
-
0029928405
-
Mechanisms of action of anti-inflammatory drugs
-
Vane JR, Botting RM. Mechanisms of action of anti-inflammatory drugs. Scand J Rheumatol 1996; 25 Suppl 102: 9-21
-
(1996)
Scand J Rheumatol
, vol.25
, Issue.102 SUPPL.
, pp. 9-21
-
-
Vane, J.R.1
Botting, R.M.2
-
109
-
-
0029983843
-
Constitutive cyclooxygenase (COX-1) and inducible cyclooxygenase (COX-2): Rationals for selective inhibition and progress to date
-
Griswold DE, Adams JL. Constitutive cyclooxygenase (COX-1) and inducible cyclooxygenase (COX-2): rationals for selective inhibition and progress to date. Med Res Rev 1996; 16: 181-206
-
(1996)
Med Res Rev
, vol.16
, pp. 181-206
-
-
Griswold, D.E.1
Adams, J.L.2
-
110
-
-
0028826483
-
Effects of nabumetone on prostanoid biosynthesis in humans
-
Cipollone F, Ganci A, Panara, et al. Effects of nabumetone on prostanoid biosynthesis in humans. Clin Pharmacol Ther 1995; 58: 335-41
-
(1995)
Clin Pharmacol Ther
, vol.58
, pp. 335-341
-
-
Cipollone, F.1
Ganci, A.2
Panara3
-
111
-
-
0024460216
-
Effects of nimesulide on cyclo-oxygenase activity in rat gastric mucosa and inflammatory exudate
-
Tofanetti O, Casciarri I, Cipolla PV, et al. Effects of nimesulide on cyclo-oxygenase activity in rat gastric mucosa and inflammatory exudate. Med Sci Res 1989; 17: 745-6
-
(1989)
Med Sci Res
, vol.17
, pp. 745-746
-
-
Tofanetti, O.1
Casciarri, I.2
Cipolla, P.V.3
-
112
-
-
0028322893
-
Selective inhibition of inducible cyclooxygenase 2 in vivo is anti-inflammatory and nonulcerogenic
-
Masferrer JL, Zweifel BS, Manning PT et al. Selective inhibition of inducible cyclooxygenase 2 in vivo is anti-inflammatory and nonulcerogenic. Proc Natl Acad Sci USA 1994; 91: 3228-32
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 3228-3232
-
-
Masferrer, J.L.1
Zweifel, B.S.2
Manning, P.T.3
-
113
-
-
0029909989
-
The clinical implications of inhibition of the inducible form of cyclo-oxygenase
-
Richardson C, Emery P. The clinical implications of inhibition of the inducible form of cyclo-oxygenase. Drug Saf 1996; 15: 249-60
-
(1996)
Drug Saf
, vol.15
, pp. 249-260
-
-
Richardson, C.1
Emery, P.2
-
114
-
-
0029955717
-
Non steroidal antiinflammatory drugs and their effects. The importance of COX 'selectivity'
-
Simon LS. Non steroidal antiinflammatory drugs and their effects. The importance of COX 'selectivity'. J Clin Rheumatol 1996; 2: 135-40
-
(1996)
J Clin Rheumatol
, vol.2
, pp. 135-140
-
-
Simon, L.S.1
-
116
-
-
8244247027
-
NSAIDs revisited cyclooxygenase 2 (COX-2) inhibitors
-
Jensen NP. NSAIDs revisited cyclooxygenase 2 (COX-2) inhibitors. Med Chem Res 1995; 5: 319-24
-
(1995)
Med Chem Res
, vol.5
, pp. 319-324
-
-
Jensen, N.P.1
-
117
-
-
0027516402
-
NS-398, a novel nonsteroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions
-
Futaki N, Yoshikawa K, Hamasaka Y, et al. NS-398, a novel nonsteroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions. Gen Pharmacol 1993; 24: 105-10
-
(1993)
Gen Pharmacol
, vol.24
, pp. 105-110
-
-
Futaki, N.1
Yoshikawa, K.2
Hamasaka, Y.3
-
118
-
-
0024569690
-
The pharmacological profile of CGP-28238, a highly potent anti-inflammatory compound
-
Wiesenberg-Böttcher I, Schweizer A, Green JR, et al. The pharmacological profile of CGP-28238, a highly potent anti-inflammatory compound. Agents Actions 1989; 26: 240-2
-
(1989)
Agents Actions
, vol.26
, pp. 240-242
-
-
Wiesenberg-Böttcher, I.1
Schweizer, A.2
Green, J.R.3
-
119
-
-
0017191297
-
4-nitro-2-phenoxymethane-sulfonanilide (R-805): A chemically novel anti-inflammatory agent
-
Swingle KF, Moore GI, Grant TJ. 4-nitro-2-phenoxymethane-sulfonanilide (R-805): a chemically novel anti-inflammatory agent. Arch Int Pharmacodyn Ther 1976; 221: 131-9
-
(1976)
Arch Int Pharmacodyn Ther
, vol.221
, pp. 131-139
-
-
Swingle, K.F.1
Moore, G.I.2
Grant, T.J.3
-
120
-
-
0025160887
-
Anti-inflammatory and safety profile of DuP 697, a novel orally effective prostaglandin synthesis inhibitor
-
Gans KR, Galbraith W, Roman RJ, et al. Anti-inflammatory and safety profile of DuP 697, a novel orally effective prostaglandin synthesis inhibitor. J Pharmacol Exp Ther 1990; 254: 180-7
-
(1990)
J Pharmacol Exp Ther
, vol.254
, pp. 180-187
-
-
Gans, K.R.1
Galbraith, W.2
Roman, R.J.3
-
121
-
-
0026746032
-
Antiarthritic profile of BF-389. A novel anti-inflammatory agent with low ulcerogenic liability
-
Wong S, Lee SJ, Frierson MR, et al. Antiarthritic profile of BF-389. A novel anti-inflammatory agent with low ulcerogenic liability. Agents Actions 1992; 37: 90-8
-
(1992)
Agents Actions
, vol.37
, pp. 90-98
-
-
Wong, S.1
Lee, S.J.2
Frierson, M.R.3
-
122
-
-
0028926813
-
New insights into the mode of action of anti-inflammatory drugs
-
Vane JR, Botting RM. New insights into the mode of action of anti-inflammatory drugs. Inflamm Res 1995; 44: 1-10
-
(1995)
Inflamm Res
, vol.44
, pp. 1-10
-
-
Vane, J.R.1
Botting, R.M.2
-
123
-
-
0001141481
-
L745.337: A selective cyclooxygenase-2 inhibitor
-
Prasit P, Black WC, Chan CC, et al. L745.337: a selective cyclooxygenase-2 inhibitor. Med Chem Res 1995; 5: 364-74
-
(1995)
Med Chem Res
, vol.5
, pp. 364-374
-
-
Prasit, P.1
Black, W.C.2
Chan, C.C.3
-
124
-
-
0026717616
-
Pharmacological studies of the new anti-inflammatory agent 3-formylamino-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one. 2nd communication: Effect on the arachidonic acid cascades
-
Tanaka K, Makino S, Shimotori T, et al. Pharmacological studies of the new anti-inflammatory agent 3-formylamino-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one. 2nd communication: effect on the arachidonic acid cascades. Arzneimittel Forschung 1992; 42: 945-50
-
(1992)
Arzneimittel Forschung
, vol.42
, pp. 945-950
-
-
Tanaka, K.1
Makino, S.2
Shimotori, T.3
-
125
-
-
0027944191
-
Selective cyclooxygenase inhibitors: Novel 1,2-diarylcyclopentenes are potent and orally active COX-2 inhibitors
-
Reitz DB, Li JJ, Norton MB, et al. Selective cyclooxygenase inhibitors: novel 1,2-diarylcyclopentenes are potent and orally active COX-2 inhibitors. J Med Chem 1994; 37: 3878-81
-
(1994)
J Med Chem
, vol.37
, pp. 3878-3881
-
-
Reitz, D.B.1
Li, J.J.2
Norton, M.B.3
-
126
-
-
0000375266
-
Novel 1,2-diarylcyclopentenes are selective, potent, and orally active cyclooxygenase inhibitors
-
Reitz DB, Li JJ, Norton MB, et al. Novel 1,2-diarylcyclopentenes are selective, potent, and orally active cyclooxygenase inhibitors. Med Chem Res 1995; 5: 351-63
-
(1995)
Med Chem Res
, vol.5
, pp. 351-363
-
-
Reitz, D.B.1
Li, J.J.2
Norton, M.B.3
-
127
-
-
0000263466
-
SC-58635 (celecoxib), a novel COX-2 selective inhibitor, is effective as a treatment for osteoarthritis (OA) in a short-term pilot study
-
Hubbard RC, Koepp RJ, Yu S, et al. SC-58635 (celecoxib), a novel COX-2 selective inhibitor, is effective as a treatment for osteoarthritis (OA) in a short-term pilot study [abstract]. Arthritis Rheum 1996; 39 Suppl. 9: S 226
-
(1996)
Arthritis Rheum
, vol.39
, Issue.9 SUPPL.
-
-
Hubbard, R.C.1
Koepp, R.J.2
Yu, S.3
-
128
-
-
0029016804
-
T-614, a novel anti rheumatic drug, inhibits both the activity and induction of cyclooxygenase-2 (COX-2) in cultured fibroblasts
-
Tanaka K, Kawasaki H, Kurata K, et al. T-614, a novel anti rheumatic drug, inhibits both the activity and induction of cyclooxygenase-2 (COX-2) in cultured fibroblasts. Jpn J Pharmacol 1995; 67: 305-14
-
(1995)
Jpn J Pharmacol
, vol.67
, pp. 305-314
-
-
Tanaka, K.1
Kawasaki, H.2
Kurata, K.3
-
129
-
-
0029888972
-
Selective inhibition of cyclooxygenase (COX-2) reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis
-
Anderson GD, Hauser SD, McGarity KL, et al. Selective inhibition of cyclooxygenase (COX-2) reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis. J Clin Invest 1996; 97: 2672-9
-
(1996)
J Clin Invest
, vol.97
, pp. 2672-2679
-
-
Anderson, G.D.1
Hauser, S.D.2
McGarity, K.L.3
-
130
-
-
0028846183
-
Activity of nimesulide on constitutive and inducible cyclooxygenases
-
Tavares IA, Bishai PM, Bennett A. Activity of nimesulide on constitutive and inducible cyclooxygenases. Arzneimittel Forschung 1995; 45 (II): 1093-5
-
(1995)
Arzneimittel Forschung
, vol.45
, Issue.2
, pp. 1093-1095
-
-
Tavares, I.A.1
Bishai, P.M.2
Bennett, A.3
-
131
-
-
84988158511
-
Selective inhibition by nimesulide, a novel non steroidal anti-inflammatory drug, with prostaglandin endoperoxide synthase-2 activity in vitro
-
Taniguchi Y, Ikesue A, Yokoyama K, et al. Selective inhibition by nimesulide, a novel non steroidal anti-inflammatory drug, with prostaglandin endoperoxide synthase-2 activity in vitro. Pharm Res 1995; 1: 173-5
-
(1995)
Pharm Res
, vol.1
, pp. 173-175
-
-
Taniguchi, Y.1
Ikesue, A.2
Yokoyama, K.3
-
133
-
-
0028860983
-
Anti-inflammatory, analgesic, antipyretic and related properties of meloxicam, a new non-steroidal anti-inflammatory agent with favourable gastrointestinal tolerance
-
Engelhardt G, Homma D, Schlegel K, et al. Anti-inflammatory, analgesic, antipyretic and related properties of meloxicam, a new non-steroidal anti-inflammatory agent with favourable gastrointestinal tolerance. Inflamm Res 1995; 44: 423-33
-
(1995)
Inflamm Res
, vol.44
, pp. 423-433
-
-
Engelhardt, G.1
Homma, D.2
Schlegel, K.3
-
134
-
-
0027201818
-
Selective inhibition of NS-398 on prostanoid production in inflamed tissue in rat carrageenan-air-pouch inflammation
-
Futaki N, Arai I, Hamasaka Y, et al. Selective inhibition of NS-398 on prostanoid production in inflamed tissue in rat carrageenan-air-pouch inflammation. J Pharm Pharmacol 1993; 45: 753-5
-
(1993)
J Pharm Pharmacol
, vol.45
, pp. 753-755
-
-
Futaki, N.1
Arai, I.2
Hamasaka, Y.3
-
135
-
-
0028122558
-
Nimesulide: An update of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy
-
Davis R, Brogden RN. Nimesulide: an update of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy. Drugs 1994; 48: 431-54
-
(1994)
Drugs
, vol.48
, pp. 431-454
-
-
Davis, R.1
Brogden, R.N.2
-
136
-
-
0028557161
-
Effects of non steroidal anti-inflammatory drugs on polymorphonuclear leukocytes functions in vitro: Focus on fenamates
-
Kankaanranta H, Moilanen E, Vapaatalo H. Effects of non steroidal anti-inflammatory drugs on polymorphonuclear leukocytes functions in vitro: focus on fenamates. Arch Pharmacol 1994; 350: 685-91
-
(1994)
Arch Pharmacol
, vol.350
, pp. 685-691
-
-
Kankaanranta, H.1
Moilanen, E.2
Vapaatalo, H.3
-
137
-
-
0026691789
-
Pharmacological studies of the new anti-inflammatory agent 3-formylamino-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one. 1st communication: Anti-inflammatory, analgesic and other related properties
-
Tanaka K, Shimotori T, Makino S, et al. Pharmacological studies of the new anti-inflammatory agent 3-formylamino-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one. 1st communication: Anti-inflammatory, analgesic and other related properties. Arzneimittel Forschung 1992; 42: 935-44
-
(1992)
Arzneimittel Forschung
, vol.42
, pp. 935-944
-
-
Tanaka, K.1
Shimotori, T.2
Makino, S.3
-
138
-
-
0027362694
-
The effect of nimesulide on prostanoid formation
-
Magni E. The effect of nimesulide on prostanoid formation. Drugs 1993; 46 Suppl. 1: 10-4
-
(1993)
Drugs
, vol.46
, Issue.1 SUPPL.
, pp. 10-14
-
-
Magni, E.1
-
139
-
-
0029983724
-
Distinct isoforms (COX-1 and COX-2) of cyclooxygenase: Possible physiological and therapeutic implications
-
Pairet M, Engelhardt E. Distinct isoforms (COX-1 and COX-2) of cyclooxygenase: possible physiological and therapeutic implications. Fund Clin Pharmacol 1996; 10: 1-15
-
(1996)
Fund Clin Pharmacol
, vol.10
, pp. 1-15
-
-
Pairet, M.1
Engelhardt, E.2
-
140
-
-
0028791313
-
Prostaglandin endoperoxide synthase isoenzymes: The clinical relevance of selective inhibition
-
Frölich JC. Prostaglandin endoperoxide synthase isoenzymes: the clinical relevance of selective inhibition. Ann Rheum Dis 1995; 54: 942-3
-
(1995)
Ann Rheum Dis
, vol.54
, pp. 942-943
-
-
Frölich, J.C.1
-
142
-
-
84996056535
-
Are there differences among nonsteroidal anti-inflammatory drugs?
-
Furst DE. Are there differences among nonsteroidal anti-inflammatory drugs? Arthritis Rheum 1994; 37: 1-9
-
(1994)
Arthritis Rheum
, vol.37
, pp. 1-9
-
-
Furst, D.E.1
-
143
-
-
0027185162
-
Gastrointestinal toxicity of newer NSAIDs
-
Lanza FL. Gastrointestinal toxicity of newer NSAIDs. Am J Gastroenterol 1993; 88: 1318-23
-
(1993)
Am J Gastroenterol
, vol.88
, pp. 1318-1323
-
-
Lanza, F.L.1
-
144
-
-
0028795025
-
Nonsteroidal anti-inflammatory drugs and the gastrointestinal tract
-
Lichtenstein DR, Syngal S, Wolfe M. Nonsteroidal anti-inflammatory drugs and the gastrointestinal tract. Arthritis Rheum 1995; 38: 5-18
-
(1995)
Arthritis Rheum
, vol.38
, pp. 5-18
-
-
Lichtenstein, D.R.1
Syngal, S.2
Wolfe, M.3
-
145
-
-
0029838240
-
NSAID gastropathy. A new understanding
-
Roth SH. NSAID gastropathy. A new understanding. Arch Intern Med 1996; 156: 1623-8
-
(1996)
Arch Intern Med
, vol.156
, pp. 1623-1628
-
-
Roth, S.H.1
-
146
-
-
0024616255
-
Toward an epidemiology of gastropathy associated with nonsteroidal anti-inflammatory drug use
-
Fries JF, Miller SR, Williams CA, et al. Toward an epidemiology of gastropathy associated with nonsteroidal anti-inflammatory drug use. Gastroenterology 1989; 96: 647-55
-
(1989)
Gastroenterology
, vol.96
, pp. 647-655
-
-
Fries, J.F.1
Miller, S.R.2
Williams, C.A.3
-
147
-
-
0024591782
-
Mechanisms of nonsteroidal anti-inflammatory drug-induced gastric damage
-
Schoen RT, Vender RJ. Mechanisms of nonsteroidal anti-inflammatory drug-induced gastric damage. Am J Med 1989; 86: 449-58
-
(1989)
Am J Med
, vol.86
, pp. 449-458
-
-
Schoen, R.T.1
Vender, R.J.2
-
148
-
-
0025670042
-
Mechanisms of NSAID-induced gastroenteropathy
-
Price AH, Fletcher M. Mechanisms of NSAID-induced gastroenteropathy. Drugs 1990; 40 Suppl. 5: 1-11
-
(1990)
Drugs
, vol.40
, Issue.5 SUPPL.
, pp. 1-11
-
-
Price, A.H.1
Fletcher, M.2
-
149
-
-
0025998097
-
Risk for serious gastrointestinal complications related to use of nonsteroidal anti-inflammatory drugs. A meta-analysis
-
Gabriel SE, Jaakkimainen L, Bombardier C. Risk for serious gastrointestinal complications related to use of nonsteroidal anti-inflammatory drugs. A meta-analysis. Ann Intern Med 1991; 115: 787-96
-
(1991)
Ann Intern Med
, vol.115
, pp. 787-796
-
-
Gabriel, S.E.1
Jaakkimainen, L.2
Bombardier, C.3
-
150
-
-
0029993460
-
Nonsteroidal anti-inflammatory drugs: Practical and theoretical considerations in their selection
-
Polisson R. Nonsteroidal anti-inflammatory drugs: practical and theoretical considerations in their selection. Am J Med 1996; 100 Suppl. 2A: 31S-6S
-
(1996)
Am J Med
, vol.100
, Issue.SUPPL. 2A
-
-
Polisson, R.1
-
151
-
-
37049186169
-
Role of surface-active phospholipids in gastric cytoprotection
-
Lichtenberger LM, Graziani LA, Dial EJ, et al. Role of surface-active phospholipids in gastric cytoprotection. Science 1983; 219: 1327-9
-
(1983)
Science
, vol.219
, pp. 1327-1329
-
-
Lichtenberger, L.M.1
Graziani, L.A.2
Dial, E.J.3
-
152
-
-
0028939954
-
Non-steroidal anti-inflammatory drugs (NSAIDs) associated with zwitterionic phospholipids: Insight into the mechanism and reversal of NSAID-induced gastrointestinal injury
-
Lichtenberger LM, Wang Z-M, Romero JJ, et al. Non-steroidal anti-inflammatory drugs (NSAIDs) associated with zwitterionic phospholipids: insight into the mechanism and reversal of NSAID-induced gastrointestinal injury. Nature Med 1995; 1: 154-8
-
(1995)
Nature Med
, vol.1
, pp. 154-158
-
-
Lichtenberger, L.M.1
Wang, Z.-M.2
Romero, J.J.3
-
153
-
-
0028945016
-
The biochemical basis of non-steroidal anti-inflammatory drug induced damage to the gastrointestinal tract: A review and a hypothesis
-
Somasundaram S, Hayllar H, Rafi S, et al. The biochemical basis of non-steroidal anti-inflammatory drug induced damage to the gastrointestinal tract: a review and a hypothesis. Scand J Gastroenterol 1995; 30: 289-99
-
(1995)
Scand J Gastroenterol
, vol.30
, pp. 289-299
-
-
Somasundaram, S.1
Hayllar, H.2
Rafi, S.3
-
154
-
-
0029916285
-
A unifying hypothesis for the mechanism of NSAID related gastrointestinal toxicity
-
Mahmud T, Scott DL, Bjarnason I. A unifying hypothesis for the mechanism of NSAID related gastrointestinal toxicity. Ann Rheum Dis 1996; 55: 211-3
-
(1996)
Ann Rheum Dis
, vol.55
, pp. 211-213
-
-
Mahmud, T.1
Scott, D.L.2
Bjarnason, I.3
-
155
-
-
0024306005
-
Mechanisms of gastrointestinal toxicity of non-steroidal anti-inflammatory drugs
-
Rainsford KD. Mechanisms of gastrointestinal toxicity of non-steroidal anti-inflammatory drugs. Scand J Gastroenterol 1989; 24 Suppl. 163: 9-16
-
(1989)
Scand J Gastroenterol
, vol.24
, Issue.163 SUPPL.
, pp. 9-16
-
-
Rainsford, K.D.1
-
156
-
-
0009654998
-
Nonsteroidal anti-inflammatory drugs: How do they damage gastroduodenal mucosa?
-
Scarpignato C. Nonsteroidal anti-inflammatory drugs: How do they damage gastroduodenal mucosa? Dig Dis 1995; 13 Suppl. 1: 9-39
-
(1995)
Dig Dis
, vol.13
, Issue.1 SUPPL.
, pp. 9-39
-
-
Scarpignato, C.1
-
157
-
-
0025078185
-
Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process
-
Wallace JL, Keenan CM, Granger DN. Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process. Am J Physiol 1990; 259: G462-7
-
(1990)
Am J Physiol
, vol.259
-
-
Wallace, J.L.1
Keenan, C.M.2
Granger, D.N.3
-
158
-
-
0027142331
-
Role of endothelial adhesion molecules in NSAID-induced gastro-mucosal injury
-
Wallace JL, McKnight W, Miyasaka M, et al. Role of endothelial adhesion molecules in NSAID-induced gastro-mucosal injury. Am J Physiol 1993; 265: G993-8
-
(1993)
Am J Physiol
, vol.265
-
-
Wallace, J.L.1
McKnight, W.2
Miyasaka, M.3
-
159
-
-
0028199216
-
Pentoxifylline prevents indomethacin induced acute gastric mucosal damage in rats: Role of tumour necrosis factor alpha
-
Santucci L, Fiorucci S, Giansanti M, et al. Pentoxifylline prevents indomethacin induced acute gastric mucosal damage in rats: role of tumour necrosis factor alpha. Gut 1994; 35: 909-15
-
(1994)
Gut
, vol.35
, pp. 909-915
-
-
Santucci, L.1
Fiorucci, S.2
Giansanti, M.3
-
160
-
-
0030045189
-
Tumor necrosis factor mediation of NSAID-induced gastric damage: Role of leukocyte adherence
-
Appleyard CB, McCafferty DM, Tigley AW, et al. Tumor necrosis factor mediation of NSAID-induced gastric damage: role of leukocyte adherence. Am J Physiol 1996; 270: G42-8
-
(1996)
Am J Physiol
, vol.270
-
-
Appleyard, C.B.1
McCafferty, D.M.2
Tigley, A.W.3
-
161
-
-
0025034767
-
Regulation of gastric mucosal integrity by endogenous nitric oxide: Interactions with prostanoids and sensory neuropeptides in the rat
-
Whittle BJR, Lopez-Belmonte J, Moncada S. Regulation of gastric mucosal integrity by endogenous nitric oxide: interactions with prostanoids and sensory neuropeptides in the rat. Br J Pharmacol 1990; 99: 607-11
-
(1990)
Br J Pharmacol
, vol.99
, pp. 607-611
-
-
Whittle, B.J.R.1
Lopez-Belmonte, J.2
Moncada, S.3
-
162
-
-
0026570451
-
Endogenous nitric oxide and sensory neuropeptides interact in the modulation of rat gastric microcirculation
-
Tepperman BL, Whittle BJR. Endogenous nitric oxide and sensory neuropeptides interact in the modulation of rat gastric microcirculation. Br J Pharmacol 1992; 105: 171-5
-
(1992)
Br J Pharmacol
, vol.105
, pp. 171-175
-
-
Tepperman, B.L.1
Whittle, B.J.R.2
-
163
-
-
0028035254
-
The development of gastrointestinal-sparing nonsteroidal anti-inflammatory drugs
-
Wallace JL, Cirino G. The development of gastrointestinal-sparing nonsteroidal anti-inflammatory drugs. Trends Pharmacol Sci 1994; 15: 405-6
-
(1994)
Trends Pharmacol Sci
, vol.15
, pp. 405-406
-
-
Wallace, J.L.1
Cirino, G.2
-
164
-
-
0027788115
-
IL-1β induces the cooexpression of both nitric oxide synthase and cyclooxygenase by islets of langerhans: Activation of cyclooxygenase by nitric oxide
-
Corhett JA, Kwon G, Turk J, etal. IL-1β induces the cooexpression of both nitric oxide synthase and cyclooxygenase by islets of langerhans: activation of cyclooxygenase by nitric oxide. Biochemistry 1993; 32: 13767-70
-
(1993)
Biochemistry
, vol.32
, pp. 13767-13770
-
-
Corhett, J.A.1
Kwon, G.2
Turk, J.3
-
165
-
-
0029443008
-
Inducible cyclooxygenase and nitric oxide synthase
-
Wu KK. Inducible cyclooxygenase and nitric oxide synthase. Adv Pharmacol 1995; 33: 179-207
-
(1995)
Adv Pharmacol
, vol.33
, pp. 179-207
-
-
Wu, K.K.1
-
167
-
-
0028268947
-
Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation
-
Salvemini D, Seibert K, Masferrer JL, et al. Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation. J Clin Invest 1994; 93: 1940-7
-
(1994)
J Clin Invest
, vol.93
, pp. 1940-1947
-
-
Salvemini, D.1
Seibert, K.2
Masferrer, J.L.3
-
168
-
-
0026661824
-
Nonessential role of leukotrienes as mediators of acute gastric mucosal injury induced by aspirin
-
Lee M, Feldman M. Nonessential role of leukotrienes as mediators of acute gastric mucosal injury induced by aspirin. Dig Dis Sci 1992; 37: 1282-7
-
(1992)
Dig Dis Sci
, vol.37
, pp. 1282-1287
-
-
Lee, M.1
Feldman, M.2
-
169
-
-
0027141933
-
Tissue-selective inhibition of prostaglandin synthesis in rat by tepoxalin: Anti-inflammatory without gastropathy?
-
Wallace JL, McCafferty DM, Carter L, et al. Tissue-selective inhibition of prostaglandin synthesis in rat by tepoxalin: anti-inflammatory without gastropathy? Gastroenterology 1993; 105: 1630-6
-
(1993)
Gastroenterology
, vol.105
, pp. 1630-1636
-
-
Wallace, J.L.1
McCafferty, D.M.2
Carter, L.3
-
170
-
-
0023555094
-
The effects of 5-lipoxygenase inhibitors and leukotriene antagonists on the development of gastric lesions induced by nonsteroidal anti-inflammatory drugs in mice
-
Rainsford KD. The effects of 5-lipoxygenase inhibitors and leukotriene antagonists on the development of gastric lesions induced by nonsteroidal anti-inflammatory drugs in mice. Agents Actions 1987; 21: 316-9
-
(1987)
Agents Actions
, vol.21
, pp. 316-319
-
-
Rainsford, K.D.1
-
171
-
-
0026579528
-
A pharmacological investigation of the role of leukotrienes in the pathogenesis of experimental NSAIDs - gastropathy
-
Vaananen PM, Keenan CM, Grisham MB, et al. A pharmacological investigation of the role of leukotrienes in the pathogenesis of experimental NSAIDs - gastropathy. Inflammation 1992; 16: 227-40
-
(1992)
Inflammation
, vol.16
, pp. 227-240
-
-
Vaananen, P.M.1
Keenan, C.M.2
Grisham, M.B.3
-
172
-
-
0027953625
-
The pharmacologic effects of 5-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-1,3,4-thiadiazole-2(3H)-thione, choline salt (Cl-986), a novel inhibitor of arachidonic acid metabolism in models of inflammation, analgesia and gastric irritation
-
Schrier DJ, Baragi VM, Connor DT, et al. The pharmacologic effects of 5-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-1,3,4-thiadiazole-2(3H)-thione, choline salt (Cl-986), a novel inhibitor of arachidonic acid metabolism in models of inflammation, analgesia and gastric irritation. Prostaglandins 1994; 47: 17-30
-
(1994)
Prostaglandins
, vol.47
, pp. 17-30
-
-
Schrier, D.J.1
Baragi, V.M.2
Connor, D.T.3
-
173
-
-
0028170934
-
Tepoxalin: A dual cyclooxygenase/5-lipoxygenase inhibitor of arachidonic acid metabolism with a potent anti-inflammatory activity and a favorable gastrointestinal profile
-
Argentieri DC, Ritchie DM, Ferro MP, et al. Tepoxalin: a dual cyclooxygenase/5-lipoxygenase inhibitor of arachidonic acid metabolism with a potent anti-inflammatory activity and a favorable gastrointestinal profile. J Pharmacol Exp Ther 1994; 271: 1399-1408
-
(1994)
J Pharmacol Exp Ther
, vol.271
, pp. 1399-1408
-
-
Argentieri, D.C.1
Ritchie, D.M.2
Ferro, M.P.3
-
174
-
-
0029621177
-
Effects of non-steroidal anti-inflammatory drugs on prostaglandin H synthase isoenzyme 2 (cyclo-oxygenase 2) production by porcine gastric mucosa in organ culture
-
Rainsford KD, Tsang S, Hunt RH, et al. Effects of non-steroidal anti-inflammatory drugs on prostaglandin H synthase isoenzyme 2 (cyclo-oxygenase 2) production by porcine gastric mucosa in organ culture. Inflammopharmacology 1995; 3: 299-310
-
(1995)
Inflammopharmacology
, vol.3
, pp. 299-310
-
-
Rainsford, K.D.1
Tsang, S.2
Hunt, R.H.3
-
175
-
-
0028325832
-
Differences in NSAID tolerability profiles: Fact or fiction?
-
Skeith KJ, Wright M, Davis P. Differences in NSAID tolerability profiles: fact or fiction? Drug Saf 1994; 10: 183-95
-
(1994)
Drug Saf
, vol.10
, pp. 183-195
-
-
Skeith, K.J.1
Wright, M.2
Davis, P.3
-
176
-
-
0025853360
-
Nonsteroidal anti-inflammatory drug use and increased risk for peptic ulcer disease in elderly persons
-
Griffin MR, Piper JM, Daugherty JR, et al. Nonsteroidal anti-inflammatory drug use and increased risk for peptic ulcer disease in elderly persons. Ann Intern Med 1991; 114: 257-63
-
(1991)
Ann Intern Med
, vol.114
, pp. 257-263
-
-
Griffin, M.R.1
Piper, J.M.2
Daugherty, J.R.3
-
177
-
-
0026097522
-
Upper gastrointestinal bleeding in relation to previous use of analgesics and non-steroidal anti-inflammatory drugs
-
Laporte JR, Carne X, Vidai X, et al. Upper gastrointestinal bleeding in relation to previous use of analgesics and non-steroidal anti-inflammatory drugs. Lancet 1991; 337: 85-9
-
(1991)
Lancet
, vol.337
, pp. 85-89
-
-
Laporte, J.R.1
Carne, X.2
Vidai, X.3
-
178
-
-
0027403880
-
Variation in the risk of peptic ulcer complications with nonsteroidal anti-inflammatory drug therapy
-
Savage RL, Moller PW, Ballantyne CL et al Variation in the risk of peptic ulcer complications with nonsteroidal anti-inflammatory drug therapy. Arthritis Rheum 1993; 36: 84-90
-
(1993)
Arthritis Rheum
, vol.36
, pp. 84-90
-
-
Savage, R.L.1
Moller, P.W.2
Ballantyne, C.L.3
-
179
-
-
0027179395
-
Variability in the risk of major gastrointestinal complications from nonaspirin nonsteroidal anti-inflammatory drugs
-
Henry D, Dobson A, Turner C. Variability in the risk of major gastrointestinal complications from nonaspirin nonsteroidal anti-inflammatory drugs. Gastroenterology 1993; 105: 1078-88
-
(1993)
Gastroenterology
, vol.105
, pp. 1078-1088
-
-
Henry, D.1
Dobson, A.2
Turner, C.3
-
180
-
-
0028353941
-
Risk of bleeding peptic ulcer associated with individual non-steroidal anti-inflammatory drugs
-
Langman MJS, Weil J, Wainwright P, et al. Risk of bleeding peptic ulcer associated with individual non-steroidal anti-inflammatory drugs. Lancet 1994; 343: 1075-8
-
(1994)
Lancet
, vol.343
, pp. 1075-1078
-
-
Langman, M.J.S.1
Weil, J.2
Wainwright, P.3
-
181
-
-
0028327671
-
Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs
-
Garcia-Rodriguez LA, Jick H. Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs. Lancet 1994; 343: 769-72
-
(1994)
Lancet
, vol.343
, pp. 769-772
-
-
Garcia-Rodriguez, L.A.1
Jick, H.2
-
182
-
-
0026529023
-
A prospective study of risk for peptic ulcer disease in seventh day adventists
-
Kurata JH, Nagawa AN, Abbey DE, et al. A prospective study of risk for peptic ulcer disease in seventh day adventists. Gastroenterology 1992; 102: 902-9
-
(1992)
Gastroenterology
, vol.102
, pp. 902-909
-
-
Kurata, J.H.1
Nagawa, A.N.2
Abbey, D.E.3
-
183
-
-
0029055187
-
Peptic ulcer and gastrointestinal hemorrhage associated with nonsteroidal anti-inflammatory drug use in patients younger than 65 years
-
Lanza LL, Walker AM, Bortnichak EA, et al. Peptic ulcer and gastrointestinal hemorrhage associated with nonsteroidal anti-inflammatory drug use in patients younger than 65 years. Arch Intern Med 1995; 155: 1371-7
-
(1995)
Arch Intern Med
, vol.155
, pp. 1371-1377
-
-
Lanza, L.L.1
Walker, A.M.2
Bortnichak, E.A.3
-
184
-
-
0029685134
-
Toward an understanding of NSAID-related adverse events: The contribution of longitudinal data
-
Fries J. Toward an understanding of NSAID-related adverse events: the contribution of longitudinal data. Scand J Rheumatol 1996; 25 Suppl. 102: 3-8
-
(1996)
Scand J Rheumatol
, vol.25
, Issue.102 SUPPL.
, pp. 3-8
-
-
Fries, J.1
-
185
-
-
0022624322
-
Non-steroidal anti-inflammatory drugs and serious gastrointestinal adverse reactions - 2
-
Committee on Safety of Medicines. Non-steroidal anti-inflammatory drugs and serious gastrointestinal adverse reactions - 2. BMJ 1986; 292: 1190-1
-
(1986)
BMJ
, vol.292
, pp. 1190-1191
-
-
-
186
-
-
0028221862
-
NSAIDs: Time to re-evaluate gut toxicity
-
Bateman DN. NSAIDs: time to re-evaluate gut toxicity. Lancet 1994; 343: 1051-2
-
(1994)
Lancet
, vol.343
, pp. 1051-1052
-
-
Bateman, D.N.1
-
187
-
-
8944227048
-
Variability in risk of gastrointestinal complications with individual non-steroidal anti-inflammatory drugs: Results of a collaborative meta-analysis
-
Henry D, Lim LY, Garcia-Rodriguez LA, et al. Variability in risk of gastrointestinal complications with individual non-steroidal anti-inflammatory drugs: results of a collaborative meta-analysis. BMJ 1996; 312: 1563-6
-
(1996)
BMJ
, vol.312
, pp. 1563-1566
-
-
Henry, D.1
Lim, L.Y.2
Garcia-Rodriguez, L.A.3
-
188
-
-
0029065563
-
Gastrointestinal damage and bleeding from non-steroidal anti-inflammatory drugs: I. Clinical and epidemiological aspects
-
Rainsford KD, Quadir M. Gastrointestinal damage and bleeding from non-steroidal anti-inflammatory drugs: I. Clinical and epidemiological aspects. Inflammopharmacology 1995; 3: 169-90
-
(1995)
Inflammopharmacology
, vol.3
, pp. 169-190
-
-
Rainsford, K.D.1
Quadir, M.2
-
189
-
-
0019421127
-
Inhibition by anti-inflammatory drugs of prostaglandin production in cultured macrophages
-
Brune K, Rainsford KD, Wagner K, et al. Inhibition by anti-inflammatory drugs of prostaglandin production in cultured macrophages. Arch Pharmacol 1981; 315: 269-76
-
(1981)
Arch Pharmacol
, vol.315
, pp. 269-276
-
-
Brune, K.1
Rainsford, K.D.2
Wagner, K.3
-
190
-
-
0023615244
-
Endoscopy-controlled study of the safely of nabumetone compared with naproxen in arthritis therapy
-
Roth SH. Endoscopy-controlled study of the safely of nabumetone compared with naproxen in arthritis therapy. Am J Med 1987; 83: 25-30
-
(1987)
Am J Med
, vol.83
, pp. 25-30
-
-
Roth, S.H.1
-
191
-
-
0023262595
-
An endoscopic comparison ot the effects of etodolac, indomethacin, ibuprofen, naproxen. and placebo on the gastrointestinal mucosa
-
Lanza F, Rack MF, Lynn M, et al. An endoscopic comparison ot the effects of etodolac, indomethacin, ibuprofen, naproxen. and placebo on the gastrointestinal mucosa. J Rheumatol 1987; 14: 338-41
-
(1987)
J Rheumatol
, vol.14
, pp. 338-341
-
-
Lanza, F.1
Rack, M.F.2
Lynn, M.3
-
192
-
-
0026081206
-
A double-blind gastroscopic evaluation of the effects of etodolac and naproxen on the gastrointestinal mucosa of rheumatic patients
-
Bianchi-Porro G, Caruso I, Petrillo M, et al. A double-blind gastroscopic evaluation of the effects of etodolac and naproxen on the gastrointestinal mucosa of rheumatic patients. J Intern Med 1991; 229: 5-8
-
(1991)
J Intern Med
, vol.229
, pp. 5-8
-
-
Bianchi-Porro, G.1
Caruso, I.2
Petrillo, M.3
-
193
-
-
0025667714
-
A 12-month postmarketing surveillance study of nabumetone: A preliminary report
-
Jenner PN. A 12-month postmarketing surveillance study of nabumetone: a preliminary report. Drugs 1990; 40 Suppl. 5: 80-6
-
(1990)
Drugs
, vol.40
, Issue.5 SUPPL.
, pp. 80-86
-
-
Jenner, P.N.1
-
194
-
-
0025690306
-
German drug monitoring studies with nabumetone
-
Stroehmann I, Fedder M, Zeidler H. German drug monitoring studies with nabumetone. Drugs 1990; 40 Suppl. 5: 38-42
-
(1990)
Drugs
, vol.40
, Issue.5 SUPPL.
, pp. 38-42
-
-
Stroehmann, I.1
Fedder, M.2
Zeidler, H.3
-
195
-
-
0025675634
-
An overview of the long-term safety experience of nabumetone
-
Wilkens RF. An overview of the long-term safety experience of nabumetone. Drugs 1990; 40 Suppl. 5: 34-7
-
(1990)
Drugs
, vol.40
, Issue.5 SUPPL.
, pp. 34-37
-
-
Wilkens, R.F.1
-
196
-
-
0024991557
-
An updated safety profile of etodolac in several thousand patients
-
Schattenkirchner M. An updated safety profile of etodolac in several thousand patients. Eur J Rheumatol Inflamm 1990; 10: 56-65
-
(1990)
Eur J Rheumatol Inflamm
, vol.10
, pp. 56-65
-
-
Schattenkirchner, M.1
-
197
-
-
0025649748
-
Nonsteroidal anti-inflammatory drug therapy and gastric side effects: Does nabumetone provide a solution?
-
Dandona P, Jeremy JY. Nonsteroidal anti-inflammatory drug therapy and gastric side effects: does nabumetone provide a solution? Drugs 1990; 40 Suppl. 5: 16-24
-
(1990)
Drugs
, vol.40
, Issue.5 SUPPL.
, pp. 16-24
-
-
Dandona, P.1
Jeremy, J.Y.2
-
198
-
-
0026487129
-
The unique pharmacologic profile of nabumetone
-
Blower PR. The unique pharmacologic profile of nabumetone. J Rheumatol 1992; 19 Suppl. 36: 13-20
-
(1992)
J Rheumatol
, vol.19
, Issue.36 SUPPL.
, pp. 13-20
-
-
Blower, P.R.1
-
199
-
-
0027359478
-
Gastric tolerability of nimesulide: A double-blind comparison of 2 oral dosage regimens and placebo
-
Marini U, Spotti D. Gastric tolerability of nimesulide: a double-blind comparison of 2 oral dosage regimens and placebo. Drugs 1993; 46 Suppl. 1: 249-52
-
(1993)
Drugs
, vol.46
, Issue.1 SUPPL.
, pp. 249-252
-
-
Marini, U.1
Spotti, D.2
-
200
-
-
0029866403
-
A 4-week, double-blind, parrallel-group study to compare the gastrointestinal effects of meloxicam 7.5 mg, meloxicam 15 mg, piroxicam 20 mg and placebo by means of faecal blood loss, endoscopy and symptom evaluation in healthy volunteers
-
Patoia L, Santucci L, Furno P, et al. A 4-week, double-blind, parrallel-group study to compare the gastrointestinal effects of meloxicam 7.5 mg, meloxicam 15 mg, piroxicam 20 mg and placebo by means of faecal blood loss, endoscopy and symptom evaluation in healthy volunteers. Br J Rheumatol 1996; 35 Suppl. 1: 61-97
-
(1996)
Br J Rheumatol
, vol.35
, Issue.1 SUPPL.
, pp. 61-97
-
-
Patoia, L.1
Santucci, L.2
Furno, P.3
-
201
-
-
0024411983
-
Endoscopic assessment of the effects of nimesulide on the gastric mucosa: Comparison with indomethacin
-
Cipollini F, Mecozzi V, Altilia F. Endoscopic assessment of the effects of nimesulide on the gastric mucosa: comparison with indomethacin. Curr Ther Res 1989; 45: 1042-8
-
(1989)
Curr Ther Res
, vol.45
, pp. 1042-1048
-
-
Cipollini, F.1
Mecozzi, V.2
Altilia, F.3
-
202
-
-
0025873243
-
Post-marketing survey of nimesulide in the short-term treatment of osteoarthritis
-
Pochobradsky MG, Mele G, Beretta A. Post-marketing survey of nimesulide in the short-term treatment of osteoarthritis. Drugs Exp Clin Res 1991; 17: 197-204
-
(1991)
Drugs Exp Clin Res
, vol.17
, pp. 197-204
-
-
Pochobradsky, M.G.1
Mele, G.2
Beretta, A.3
-
203
-
-
0027430946
-
Long-term tolerability profile of nimesulide in the treatment of osteoarthritis
-
Dreiser RL, Benvelli DC. Long-term tolerability profile of nimesulide in the treatment of osteoarthritis. Drugs 1993; 46 Suppl. 1: 270-4
-
(1993)
Drugs
, vol.46
, Issue.1 SUPPL.
, pp. 270-274
-
-
Dreiser, R.L.1
Benvelli, D.C.2
-
204
-
-
0029865433
-
A six-month double-blind trial to compare the efficacy and safety of meloxicam 7.5 mg daily and naproxen 750 mg daily in patients with rheumatoid arthritis
-
Wojtulewski JA, Schattenkirchner M, Barcelo P, et al. A six-month double-blind trial to compare the efficacy and safety of meloxicam 7.5 mg daily and naproxen 750 mg daily in patients with rheumatoid arthritis. Br J Rheumatol 1996; 35 Suppl. 1: 22-8
-
(1996)
Br J Rheumatol
, vol.35
, Issue.1 SUPPL.
, pp. 22-28
-
-
Wojtulewski, J.A.1
Schattenkirchner, M.2
Barcelo, P.3
-
205
-
-
0029868836
-
Meloxicam in osteoarthritis: A 6-month, double-blind comparison with diclofenac sodium
-
Hosie J, Distel M, Bluhmki E. Meloxicam in osteoarthritis: a 6-month, double-blind comparison with diclofenac sodium. Br J Rheumatol 1996; 35 Suppl. 1: 39-43
-
(1996)
Br J Rheumatol
, vol.35
, Issue.1 SUPPL.
, pp. 39-43
-
-
Hosie, J.1
Distel, M.2
Bluhmki, E.3
-
206
-
-
0029870734
-
A double-blind study to compare the efficacy and safety of meloxicam 15 mg with piroxicam 20 mg in patients with osteoarthritis of the hip
-
Linden B, Distel M, Bluhmki E. A double-blind study to compare the efficacy and safety of meloxicam 15 mg with piroxicam 20 mg in patients with osteoarthritis of the hip. Br J Rheumatol 1996; 35 Suppl. 1: 35-8
-
(1996)
Br J Rheumatol
, vol.35
, Issue.1 SUPPL.
, pp. 35-38
-
-
Linden, B.1
Distel, M.2
Bluhmki, E.3
-
207
-
-
0030007321
-
Global analysis of gastrointestinal safety of a new NSAID, meloxicam
-
Distel M, Mueller C, Bluhmki E. Global analysis of gastrointestinal safety of a new NSAID, meloxicam. Inflammopharmacology 1996; 4: 71-8
-
(1996)
Inflammopharmacology
, vol.4
, pp. 71-78
-
-
Distel, M.1
Mueller, C.2
Bluhmki, E.3
-
208
-
-
0029979358
-
Safety of meloxicam: A global analysis of clinical trials
-
Distel M, Mueller C, Bluhmki E, et al. Safety of meloxicam: a global analysis of clinical trials. Br J Rheumatol 1996; 35 Suppl. 1: 68-77
-
(1996)
Br J Rheumatol
, vol.35
, Issue.1 SUPPL.
, pp. 68-77
-
-
Distel, M.1
Mueller, C.2
Bluhmki, E.3
-
209
-
-
0029867820
-
Review of clinical trials and benefit/risk ratio of meloxicam
-
Barner A. Review of clinical trials and benefit/risk ratio of meloxicam. Scand J Rheumatol 1996; 25 Suppl. 102: 29-37
-
(1996)
Scand J Rheumatol
, vol.25
, Issue.102 SUPPL.
, pp. 29-37
-
-
Barner, A.1
-
210
-
-
0029650018
-
NSAIDs, COX-2 inhibitors, and the gut
-
Benett A, Tavares IA. NSAIDs, COX-2 inhibitors, and the gut [letter]. Lancet 1995; 346: 1105
-
(1995)
Lancet
, vol.346
, pp. 1105
-
-
Benett, A.1
Tavares, I.A.2
-
211
-
-
0027993458
-
Upregulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas
-
Eberhart CE, Coffey RJ, Radhika A, et al. Upregulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 1994; 107: 1183-8
-
(1994)
Gastroenterology
, vol.107
, pp. 1183-1188
-
-
Eberhart, C.E.1
Coffey, R.J.2
Radhika, A.3
-
212
-
-
0029117472
-
Expression of cyclooxygenase-1 and -2 in human colorectal cancer
-
Sano H, Kawahito Y, Wilder RL, et al. Expression of cyclooxygenase-1 and -2 in human colorectal cancer. Cancer Res 1995; 55: 3785-9
-
(1995)
Cancer Res
, vol.55
, pp. 3785-3789
-
-
Sano, H.1
Kawahito, Y.2
Wilder, R.L.3
-
213
-
-
0029008617
-
Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer
-
Kargman SL, O'Neill GP, Vickers PJ, et al. Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer. Cancer Res 1995; 55: 2556-9
-
(1995)
Cancer Res
, vol.55
, pp. 2556-2559
-
-
Kargman, S.L.1
O'Neill, G.P.2
Vickers, P.J.3
-
214
-
-
0028803728
-
Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
-
Tsujii M, DuBois R. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 1995; 83: 493-501
-
(1995)
Cell
, vol.83
, pp. 493-501
-
-
Tsujii, M.1
DuBois, R.2
-
215
-
-
0026761738
-
Aspirin and the potential role of prostaglandins in colon cancer
-
Marnett LJ. Aspirin and the potential role of prostaglandins in colon cancer. Cancer Res 1992; 52: 5575-89
-
(1992)
Cancer Res
, vol.52
, pp. 5575-5589
-
-
Marnett, L.J.1
-
216
-
-
0029899153
-
Prostaglandin H synthase 2 is expressed abnormally in human colocancer: Evidence for a transcriptional effect
-
Kutchera W, Jones DA, Matsunami N, et al. Prostaglandin H synthase 2 is expressed abnormally in human colocancer: evidence for a transcriptional effect. Proc Natl Acad Sci USA 1996; 93: 4816-20
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 4816-4820
-
-
Kutchera, W.1
Jones, D.A.2
Matsunami, N.3
-
219
-
-
0028556801
-
Aspirin use and risk for colorectal cancer and adenoma in male health professionals
-
Giovannuci E, Rimm EB, Stampfer MJ, et al. Aspirin use and risk for colorectal cancer and adenoma in male health professionals. Ann Intern Med 1994; 121: 241-6
-
(1994)
Ann Intern Med
, vol.121
, pp. 241-246
-
-
Giovannuci, E.1
Rimm, E.B.2
Stampfer, M.J.3
-
220
-
-
0028344925
-
Aspirin and nonsteroidal anti-inflammatory drug use and the risk of subsequent colorectal cancer
-
Peleg II, Hilda T, Brown SH, et al. Aspirin and nonsteroidal anti-inflammatory drug use and the risk of subsequent colorectal cancer. Arch Intern Med 1994; 154: 394-9
-
(1994)
Arch Intern Med
, vol.154
, pp. 394-399
-
-
Peleg, I.I.1
Hilda, T.2
Brown, S.H.3
-
221
-
-
0028085411
-
Nonsteroidal anti-inflammatory drugs and colorectal cancer
-
Muscat JE, Stellman SD, Wynder EL. Nonsteroidal anti-inflammatory drugs and colorectal cancer. Cancer 1994; 74: 1847-54
-
(1994)
Cancer
, vol.74
, pp. 1847-1854
-
-
Muscat, J.E.1
Stellman, S.D.2
Wynder, E.L.3
-
222
-
-
0030038519
-
Nonsteroidal anti-inflammatory drugs inhibit the proliferation of colon adenocarcinoma cells: Effects on cell cycle and apoptosis
-
Shiff SJ, Koutsos MI, Qiao L, et al. Nonsteroidal anti-inflammatory drugs inhibit the proliferation of colon adenocarcinoma cells: effects on cell cycle and apoptosis. Exp Cell Res 1996; 22: 179-88
-
(1996)
Exp Cell Res
, vol.22
, pp. 179-188
-
-
Shiff, S.J.1
Koutsos, M.I.2
Qiao, L.3
-
223
-
-
0029088472
-
The effects of sulindac on colorectal proliferation and apoptosis in familial adenomatous polyposis
-
Pasricha PJ, Bedi A, O'Connor K, et al. The effects of sulindac on colorectal proliferation and apoptosis in familial adenomatous polyposis. Gastroenterology 1995; 109: 994-8
-
(1995)
Gastroenterology
, vol.109
, pp. 994-998
-
-
Pasricha, P.J.1
Bedi, A.2
O'Connor, K.3
-
224
-
-
0029148381
-
Aspirin as prophylaxis against colorectal cancer
-
Marcus AJ. Aspirin as prophylaxis against colorectal cancer. N Engl J Med 1995; 333: 656-8
-
(1995)
N Engl J Med
, vol.333
, pp. 656-658
-
-
Marcus, A.J.1
-
225
-
-
0028884128
-
Induction of cyclooxygenase-2 mRNA and protein following transient focal ischemia in the rat brain
-
Planas AM, Soriano MA, Rodriguez-Farre E, et al. Induction of cyclooxygenase-2 mRNA and protein following transient focal ischemia in the rat brain. Neurosci Lett 1995; 200: 187-90
-
(1995)
Neurosci Lett
, vol.200
, pp. 187-190
-
-
Planas, A.M.1
Soriano, M.A.2
Rodriguez-Farre, E.3
-
226
-
-
0028984596
-
Expression of cyclooxygenase 2 in rat brain following kainate treatment
-
Chen J, Marsh T, Zhang JS, et al. Expression of cyclooxygenase 2 in rat brain following kainate treatment. Neuroreport 1995; 6: 245-8
-
(1995)
Neuroreport
, vol.6
, pp. 245-248
-
-
Chen, J.1
Marsh, T.2
Zhang, J.S.3
-
227
-
-
0030031692
-
Cyclooxygenase-2 induction in cerebral cortex: An intracellular response to synaptic excitation
-
Adams J, Collaço-Moraes Y, De Belleroche J. Cyclooxygenase-2 induction in cerebral cortex: an intracellular response to synaptic excitation. J Neurochem 1996; 66: 6-13
-
(1996)
J Neurochem
, vol.66
, pp. 6-13
-
-
Adams, J.1
Collaço-Moraes, Y.2
De Belleroche, J.3
-
228
-
-
0029928067
-
Mechanisms of apoptosis as drug targets in the central nervous system
-
Spence P, Franco R, Wood A, et al. Mechanisms of apoptosis as drug targets in the central nervous system. Expert Opin Ther Patents 1996; 6: 345-66
-
(1996)
Expert Opin Ther Patents
, vol.6
, pp. 345-366
-
-
Spence, P.1
Franco, R.2
Wood, A.3
-
230
-
-
0029587620
-
Inflammatory and immunological mechanisms in Alzheimer's disease
-
Hampel H, Müller N. Inflammatory and immunological mechanisms in Alzheimer's disease. Drug News Perspect 1995; 8: 599-608
-
(1995)
Drug News Perspect
, vol.8
, pp. 599-608
-
-
Hampel, H.1
Müller, N.2
-
231
-
-
0029879704
-
Neuroinflammatory mechanisms in Alzheimer's disease: New opportunities for drug discovery
-
Cochran FR, Vitek MP. Neuroinflammatory mechanisms in Alzheimer's disease: new opportunities for drug discovery. Expert Opin Invest Drugs 1996; 5: 449-55
-
(1996)
Expert Opin Invest Drugs
, vol.5
, pp. 449-455
-
-
Cochran, F.R.1
Vitek, M.P.2
-
232
-
-
0000791216
-
NSAIDs may reduce risk of Alzheimer's disease
-
Fricker J. NSAIDs may reduce risk of Alzheimer's disease [editorial]. Lancet 1996; 347: 958
-
(1996)
Lancet
, vol.347
, pp. 958
-
-
Fricker, J.1
-
233
-
-
0025138493
-
Renal eicosanoids
-
Norris SH. Renal eicosanoids. Semin Nephrol 1990; 10: 64-88
-
(1990)
Semin Nephrol
, vol.10
, pp. 64-88
-
-
Norris, S.H.1
-
234
-
-
0025844875
-
The role of prostaglandins in NSAID induced renal dysfunction
-
Toto RD. The role of prostaglandins in NSAID induced renal dysfunction. J Rheumatol 1991; 18 Suppl. 28: 22-5
-
(1991)
J Rheumatol
, vol.18
, Issue.28 SUPPL.
, pp. 22-25
-
-
Toto, R.D.1
-
235
-
-
0027250987
-
Anti-inflammatory drugs and their effects on cartilage synthesis and renal function
-
Shield MJ. Anti-inflammatory drugs and their effects on cartilage synthesis and renal function. Eur J Rheumatol Inflamm 1993; 13: 7-16
-
(1993)
Eur J Rheumatol Inflamm
, vol.13
, pp. 7-16
-
-
Shield, M.J.1
-
236
-
-
0018033563
-
Immunohistochemical localization of the prostaglandin-forming cyclooxygenase in the renal cortex
-
Smith WL, Bell TG. Immunohistochemical localization of the prostaglandin-forming cyclooxygenase in the renal cortex. Am J Physiol 1978; 235: F451-7
-
(1978)
Am J Physiol
, vol.235
-
-
Smith, W.L.1
Bell, T.G.2
-
237
-
-
0028107576
-
Regulation of prostaglandin endoperoxide synthase gene expression in rat mesangial cells by interleukin-1β
-
Rzymkiewicz D, Leingang K, Baird N, et al. Regulation of prostaglandin endoperoxide synthase gene expression in rat mesangial cells by interleukin-1β. Am J Physiol 1994; 266: F39-45
-
(1994)
Am J Physiol
, vol.266
-
-
Rzymkiewicz, D.1
Leingang, K.2
Baird, N.3
-
238
-
-
0028919725
-
Endothelin-1 induction of cyclooxygenase-2 expression in rat mesangial cells
-
Hughes AK, Padilla E, Kutchera WA, et al. Endothelin-1 induction of cyclooxygenase-2 expression in rat mesangial cells. Kidney Int 1995; 47: 53-61
-
(1995)
Kidney Int
, vol.47
, pp. 53-61
-
-
Hughes, A.K.1
Padilla, E.2
Kutchera, W.A.3
|