메뉴 건너뛰기




Volumn 97, Issue 2, 1996, Pages 469-476

Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression

Author keywords

angiogenesis; endothelial cells; flt 1; ischemia; KDR

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; IODINE 125; LACTIC ACID; NEUTRALIZING ANTIBODY; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

EID: 0030030668     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118437     Document Type: Article
Times cited : (343)

References (45)
  • 1
  • 2
  • 4
    • 0028344109 scopus 로고
    • Therapeutic angiogenesis: A single ultra-arterial of bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hindlimb model
    • Takeshita, S., L. P. Zheng, E. Brogi, M. Kearney, L. O. Pu, S. Bunting, N. Ferrara, J. F. Symes, and J. M. Isner 1994. Therapeutic angiogenesis: a single ultra-arterial of bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hindlimb model. J. Clin. Invest. 93 662-670
    • (1994) J. Clin. Invest. , vol.93 , pp. 662-670
    • Takeshita, S.1    Zheng, L.P.2    Brogi, E.3    Kearney, M.4    Pu, L.O.5    Bunting, S.6    Ferrara, N.7    Symes, J.F.8    Isner, J.M.9
  • 5
    • 0026505773 scopus 로고
    • Molecular and biological properties of the vascular endothelial growth factor family of protein
    • Ferrara, N , K. A. Houch, L. B Jakeman, and D. W Leung 1992 Molecular and biological properties of the vascular endothelial growth factor family of protein. Endocrinol. Rev. 13:18-32
    • (1992) Endocrinol. Rev. , vol.13 , pp. 18-32
    • Ferrara, N.1    Houch, K.A.2    Jakeman, L.B.3    Leung, D.W.4
  • 8
    • 0027997863 scopus 로고
    • Different signal transduction properties of KDR and flt-1, two receptors for vascular endothelial growth factor
    • Waltenberger, J., L. Claesson-Welsh, A. Siegbahn, M. Shibuya, and C. H. Heldin 1994. Different signal transduction properties of KDR and flt-1, two receptors for vascular endothelial growth factor. J. Biol Chem. 269:26988-26995.
    • (1994) J. Biol Chem. , vol.269 , pp. 26988-26995
    • Waltenberger, J.1    Claesson-Welsh, L.2    Siegbahn, A.3    Shibuya, M.4    Heldin, C.H.5
  • 9
    • 0026756163 scopus 로고
    • Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocyles during wound healing
    • Brown, L F., K. T Yeo, B. Berse, T. K. Yeo, D. R. Senger, H. F. Dvorak, and L. Van de Water. 1992. Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocyles during wound healing. J. Exp. Med. 176:1375-1379.
    • (1992) J. Exp. Med. , vol.176 , pp. 1375-1379
    • Brown, L.F.1    Yeo, K.T.2    Berse, B.3    Yeo, T.K.4    Senger, D.R.5    Dvorak, H.F.6    Van De Water, L.7
  • 10
    • 0028815295 scopus 로고
    • Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization
    • Pierce, E. A., R. L. Avery, E. D. Foley, L. P. Aiello, and L. E. H. Smith. 1995. Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization. Proc. Natl. Acad. Sci. USA 92:905-909.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 905-909
    • Pierce, E.A.1    Avery, R.L.2    Foley, E.D.3    Aiello, L.P.4    Smith, L.E.H.5
  • 12
    • 0028030470 scopus 로고
    • Upregulation of vascular endothelial growth factor expression induced by myocardial ischaemia: Implications for coronary angiogenesis
    • Banai, S., D Shweiki, A. Pinson, M. Chandra, G. Lazarovici, and E. Keshet. 1994. Upregulation of vascular endothelial growth factor expression induced by myocardial ischaemia: implications for coronary angiogenesis. Cardiovasc Res 28.1176-1179.
    • (1994) Cardiovasc Res , vol.28 , pp. 1176-1179
    • Banai, S.1    Shweiki, D.2    Pinson, A.3    Chandra, M.4    Lazarovici, G.5    Keshet, E.6
  • 13
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-mitiated angiogenesis
    • Shweiki, D , A. Itin, D. Soffer, and E. Keshet. 1992. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-mitiated angiogenesis. Science (Wash. DC). 359:843-845
    • (1992) Science (Wash. DC) , vol.359 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3    Keshet, E.4
  • 14
    • 0026446102 scopus 로고
    • Vascular endothelial growth factor is a potential tumor angiogenesis factor in human gliomas in vivo
    • Plate, K. H., G. Breier, H. A. Weich, and W. Risau. 1992 Vascular endothelial growth factor is a potential tumor angiogenesis factor in human gliomas in vivo. Nature (Lond.). 359:845-848.
    • (1992) Nature (Lond.) , vol.359 , pp. 845-848
    • Plate, K.H.1    Breier, G.2    Weich, H.A.3    Risau, W.4
  • 16
    • 0028798251 scopus 로고
    • Expression of endothelial cell-specific receptor tyrosine kinases and growth factors in human brain tumors
    • Hatva, E., A. Kaipainen, P. Mentula, J. Jaaskelainen, A. Paetau, M. Haltia. and K Alitalo. 1995. Expression of endothelial cell-specific receptor tyrosine kinases and growth factors in human brain tumors. Am J. Pathol. 146: 368-378.
    • (1995) Am J. Pathol. , vol.146 , pp. 368-378
    • Hatva, E.1    Kaipainen, A.2    Mentula, P.3    Jaaskelainen, J.4    Paetau, A.5    Haltia, M.6    Alitalo, K.7
  • 17
    • 0028100605 scopus 로고
    • Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only
    • Brogi, E , T. Wu, A Namiki, and J. M. Isner. 1994. Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only Circulation 90:649-652.
    • (1994) Circulation , vol.90 , pp. 649-652
    • Brogi, E.1    Wu, T.2    Namiki, A.3    Isner, J.M.4
  • 18
    • 0028641306 scopus 로고
    • Quantitative RT PCR assay detecting the transcriptional induction of vascular endothelial growth factor under hypoxia Biochem Biophys
    • Iizuki, M., M. Yamauchi, K. Ando, N. Hon, Y. Furusawa, H. Itsukaichi, K. Fukutsu, and H. Morya 1994. Quantitative RT PCR assay detecting the transcriptional induction of vascular endothelial growth factor under hypoxia Biochem Biophys. Res Commun 205:1474-1480.
    • (1994) Res Commun , vol.205 , pp. 1474-1480
    • Iizuki, M.1    Yamauchi, M.2    Ando, K.3    Hon, N.4    Furusawa, Y.5    Itsukaichi, H.6    Fukutsu, K.7    Morya, H.8
  • 19
    • 0026786660 scopus 로고
    • Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: Implications for vascular collapse
    • Boucher, Y., and R. K. Jain 1992. Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: implications for vascular collapse. Cancer Res 52:5110-5114.
    • (1992) Cancer Res , vol.52 , pp. 5110-5114
    • Boucher, Y.1    Jain, R.K.2
  • 20
    • 0028870050 scopus 로고
    • Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implications for tumor angiogenesis
    • Shweiki, D., M. Neeman, A. Itin, and E. Keshet. 1995. Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor angiogenesis Proc. Natl Acad Sci. USA 92:768-772.
    • (1995) Proc. Natl Acad Sci. USA , vol.92 , pp. 768-772
    • Shweiki, D.1    Neeman, M.2    Itin, A.3    Keshet, E.4
  • 21
    • 0027424647 scopus 로고
    • Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth
    • Peters, K. G., C DeVries, and L. T. Williams. 1993. Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth. Proc. Natl. Acad. Sci USA. 90:8915-8919.
    • (1993) Proc. Natl. Acad. Sci USA , vol.90 , pp. 8915-8919
    • Peters, K.G.1    Devries, C.2    Williams, L.T.3
  • 23
    • 0028815417 scopus 로고
    • Site-specific therapeutic angiogenesis following systemic administration of vascular endothelial growth factor
    • Banters, C., T. Asahara, L. Zheng, S. Takeshita, S. Bunting, N. Ferrara, J F. Symes, and J. M, Isner. 1995. Site-specific therapeutic angiogenesis following systemic administration of vascular endothelial growth factor. J. Vasc Surg. 21:314-325.
    • (1995) J. Vasc Surg. , vol.21 , pp. 314-325
    • Banters, C.1    Asahara, T.2    Zheng, L.3    Takeshita, S.4    Bunting, S.5    Ferrara, N.6    Symes, J.F.7    Isner, J.M.8
  • 24
    • 0015822275 scopus 로고
    • Culture of human endothelial cells derived from umbilical veins
    • Jaffe, E. A., R. L. Nachman, C. G. Becker, and C R. Minick 1973. Culture of human endothelial cells derived from umbilical veins. J. Clin Invest. 52: 2745-2756
    • (1973) J. Clin Invest. , vol.52 , pp. 2745-2756
    • Jaffe, E.A.1    Nachman, R.L.2    Becker, C.G.3    Minick, C.R.4
  • 25
    • 0026466922 scopus 로고
    • Smooth muscle cell outgrowth from human atherosclerotic plaque: Implications for the assessment of lesion biology
    • Pickering, J G., L. Weir, K. Rosenfield, J. Stetz, J. Jekanowski, and J. M. Isner. 1992. Smooth muscle cell outgrowth from human atherosclerotic plaque: implications for the assessment of lesion biology. J. Am. Coll. Cardiol. 20:1430-1439.
    • (1992) J. Am. Coll. Cardiol. , vol.20 , pp. 1430-1439
    • Pickering, J.G.1    Weir, L.2    Rosenfield, K.3    Stetz, J.4    Jekanowski, J.5    Isner, J.M.6
  • 26
    • 0021828496 scopus 로고
    • Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation
    • Whitman, M., D. R. Kaplan, B. Schaffhausen, L. Cantley, and T. M. Roberts 1985. Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation. Nature. (Lond.). 315:239-242.
    • (1985) Nature. (Lond.) , vol.315 , pp. 239-242
    • Whitman, M.1    Kaplan, D.R.2    Schaffhausen, B.3    Cantley, L.4    Roberts, T.M.5
  • 27
    • 0026502754 scopus 로고
    • Binding sites for vascular endothelial growth factor are localized on endothelial cells in adult rat tissues
    • Jakeman, L. B., J. Winer, G. L. Bennett, C. A Altar, and N Ferrara. 1992. Binding sites for vascular endothelial growth factor are localized on endothelial cells in adult rat tissues. J. Clin. Invest. 89:244-253.
    • (1992) J. Clin. Invest. , vol.89 , pp. 244-253
    • Jakeman, L.B.1    Winer, J.2    Bennett, G.L.3    Altar, C.A.4    Ferrara, N.5
  • 28
    • 0025944147 scopus 로고
    • Interaction of vasculotropin/vascular endothehal cell growth factor with human umbilical vein endothelial cell: Binding, internalization, degradation, and biological effects
    • Bikfalvi, A., C. Sauzeau, H. Moukadiri, J. Maclouf, N. Busso, M. Bryckaert, J. Plouet, and G. Tobelem. 1991. Interaction of vasculotropin/vascular endothehal cell growth factor with human umbilical vein endothelial cell: binding, internalization, degradation, and biological effects. J. Cell. Physiol. 149:50-59
    • (1991) J. Cell. Physiol. , vol.149 , pp. 50-59
    • Bikfalvi, A.1    Sauzeau, C.2    Moukadiri, H.3    Maclouf, J.4    Busso, N.5    Bryckaert, M.6    Plouet, J.7    Tobelem, G.8
  • 29
    • 0025851348 scopus 로고
    • Basic fibroblast growth factor is efficiently released from a cytosolic storage site through plasma membrane disruptions of endothelial cells
    • Muthukrishnan, L., E. Warder, and P. L. McNeil. 1991. Basic fibroblast growth factor is efficiently released from a cytosolic storage site through plasma membrane disruptions of endothelial cells. J. Cell. Physiol. 148:1-16
    • (1991) J. Cell. Physiol. , vol.148 , pp. 1-16
    • Muthukrishnan, L.1    Warder, E.2    McNeil, P.L.3
  • 30
    • 0022408487 scopus 로고
    • Biphasic effects of type β transforming growth factor on epidermal growth factor receptors in NRK fibroblasts
    • Assoian, R. K. 1994. Biphasic effects of type β transforming growth factor on epidermal growth factor receptors in NRK fibroblasts. J. Biol. Chem 260:9613-9617.
    • (1994) J. Biol. Chem , vol.260 , pp. 9613-9617
    • Assoian, R.K.1
  • 31
    • 0026163812 scopus 로고
    • Hypoxia increases production of interleukin-1 and tumor necrosis factor by human mononuclear cells
    • Ghezzi. P , C. A Dinarello, M. Bianchi, M. E. Rosandich, J. E. Repine, and C. W. White. 1991. Hypoxia increases production of interleukin-1 and tumor necrosis factor by human mononuclear cells. Cytokine. 3:189-194.
    • (1991) Cytokine , vol.3 , pp. 189-194
    • Ghezzi, P.1    Dinarello, C.A.2    Bianchi, M.3    Rosandich, M.E.4    Repine, J.E.5    White, C.W.6
  • 32
    • 0028940664 scopus 로고
    • Increased gene expression of VEGF and the VEGF receptors KDR/Flk and Flt in lungs exposed to acute or chronic hypoxia
    • Tuder, R. M., B. E Flook, and N. F Voelkel 1995. Increased gene expression of VEGF and the VEGF receptors KDR/Flk and Flt in lungs exposed to acute or chronic hypoxia J. Clin. Invest. 95:1798-1807.
    • (1995) J. Clin. Invest. , vol.95 , pp. 1798-1807
    • Tuder, R.M.1    Flook, B.E.2    Voelkel, N.F.3
  • 33
    • 0028929991 scopus 로고
    • Upregulation of vascular endothelial growth factor and its receptors in von Hippel-Lindau disease-associated and sporadic hemangioblastomas
    • Wizigmann-Voos, S., G. Breier, W. Risau, and K. H Plate. 1995. Upregulation of vascular endothelial growth factor and its receptors in von Hippel-Lindau disease-associated and sporadic hemangioblastomas. Cancer Res. 55. 1358-1364
    • (1995) Cancer Res. , vol.55 , pp. 1358-1364
    • Wizigmann-Voos, S.1    Breier, G.2    Risau, W.3    Plate, K.H.4
  • 34
    • 0028090642 scopus 로고
    • Vascular endothelial growth factor and glioma angiogenesis: Coordinate induction of VEGF receptors., distribution of VEGF protein and possible in vivo regulatory mechanisms
    • Plate, K. H., G. Breier, H. A. Weich, H D. Mennel, and W. Risau. 1994. Vascular endothelial growth factor and glioma angiogenesis: coordinate induction of VEGF receptors., distribution of VEGF protein and possible in vivo regulatory mechanisms. Int J Cancer 59:520-529.
    • (1994) Int J Cancer , vol.59 , pp. 520-529
    • Plate, K.H.1    Breier, G.2    Weich, H.A.3    Mennel, H.D.4    Risau, W.5
  • 35
    • 0028935608 scopus 로고
    • Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis
    • Warren, R S., H. Yuan, M R. Math, N. A. Gillett. and N. Ferrara. 1995. Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis. J Clin. Invest. 95: 1789-1797.
    • (1995) J Clin. Invest. , vol.95 , pp. 1789-1797
    • Warren, R.S.1    Yuan, H.2    Math, M.R.3    Gillett, N.A.4    Ferrara, N.5
  • 36
    • 0026669801 scopus 로고
    • Antigenic heterogeneity of vascular endothelium
    • Page, C , M. Rose, M. Yacoub, and R. Pigott. 1992. Antigenic heterogeneity of vascular endothelium Am J Pathol. 141:673-683.
    • (1992) Am J Pathol. , vol.141 , pp. 673-683
    • Page, C.1    Rose, M.2    Yacoub, M.3    Pigott, R.4
  • 37
    • 0028883260 scopus 로고
    • Comparative analysis of vascular endothelial growth factor receptors on retinal and aortic vascular endothelial cells
    • Thieme, H., L. P. Aiello, H. Takagi, N. Ferrara and G. L. King. 1995. Comparative analysis of vascular endothelial growth factor receptors on retinal and aortic vascular endothelial cells. Diabetes 44.98-103.
    • (1995) Diabetes , vol.44 , pp. 98-103
    • Thieme, H.1    Aiello, L.P.2    Takagi, H.3    Ferrara, N.4    King, G.L.5
  • 38
    • 0028134936 scopus 로고
    • Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Fit-1 but not to Flk-1/ KDR
    • Park, J E , H. H. Chen, J Winer, K. A. Houck, and N Ferrara. 1994 Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Fit-1 but not to Flk-1/ KDR. J. Biol. Chem. 269.25646-25654.
    • (1994) J. Biol. Chem. , vol.269 , pp. 25646-25654
    • Park, J.E.1    Chen, H.H.2    Winer, J.3    Houck, K.A.4    Ferrara, N.5
  • 39
    • 0028174337 scopus 로고
    • Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant
    • Millauer, B., L. K. Shawver, K. H. Plate, W. Risau, and A. Ullrich. 1994 Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant. Nature (Lond ). 367:576-579
    • (1994) Nature (Lond ) , vol.367 , pp. 576-579
    • Millauer, B.1    Shawver, L.K.2    Plate, K.H.3    Risau, W.4    Ullrich, A.5
  • 40
    • 0027466849 scopus 로고
    • High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis
    • Millauer, B., S. Wizigmann-Voos, H. Schnurch, R. Martinez, N. P. H. Moller, W Risau, and A. Ullrich 1993 High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell. 72:835-846.
    • (1993) Cell , vol.72 , pp. 835-846
    • Millauer, B.1    Wizigmann-Voos, S.2    Schnurch, H.3    Martinez, R.4    Moller, N.P.H.5    Risau, W.6    Ullrich, A.7
  • 41
    • 0027053487 scopus 로고
    • Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro
    • Pepper, M. S., N. Ferrara, L. Orci. and R. Montesano. 1992. Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro Biochem. Biophys, Res. Commun 189:824-831.
    • (1992) Biochem. Biophys, Res. Commun , vol.189 , pp. 824-831
    • Pepper, M.S.1    Ferrara, N.2    Orci, L.3    Montesano, R.4
  • 42
    • 0027133163 scopus 로고
    • Synergistic effects of vascular endothelial growth factor and basic fibroblast growth factor on the proliferation of bovine capillary endothelial cells within collagen gels
    • Goto, F., K. Goto, K. Weindel, and J. Folkman. 1993 Synergistic effects of vascular endothelial growth factor and basic fibroblast growth factor on the proliferation of bovine capillary endothelial cells within collagen gels. Lab. Invest 69:508-517.
    • (1993) Lab. Invest , vol.69 , pp. 508-517
    • Goto, F.1    Goto, K.2    Weindel, K.3    Folkman, J.4
  • 43
    • 0027173065 scopus 로고
    • Transforming growth factor-β1 stimulates macrophage urokinase expression and release of matrix-bound basic fibroblast growth factor
    • Falcone, D. J., T. A. McCaffrey, A. Haimovitz-Friedman, and M. Garcia. 1993 Transforming growth factor-β1 stimulates macrophage urokinase expression and release of matrix-bound basic fibroblast growth factor. J. Cell. Physiol. 155:595-605.
    • (1993) J. Cell. Physiol. , vol.155 , pp. 595-605
    • Falcone, D.J.1    McCaffrey, T.A.2    Haimovitz-Friedman, A.3    Garcia, M.4
  • 44
    • 0013624595 scopus 로고
    • Tumor necrosis factor α, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo
    • Frater-Schroder, M., W. Risau, R. Hallmann, P. Gautschi, and P. Bohlen. 1987 Tumor necrosis factor α, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo. Prot. Natl Acad. Sci USA. 84:5277-5281.
    • (1987) Prot. Natl Acad. Sci USA , vol.84 , pp. 5277-5281
    • Frater-Schroder, M.1    Risau, W.2    Hallmann, R.3    Gautschi, P.4    Bohlen, P.5
  • 45
    • 0028356398 scopus 로고
    • Homologous and heterologous regulation of α-melanocyte stimulating hormone receptors in human and mouse melanoma cell lines
    • Sigegrist, W., S. Stutz, and A. N Eberle 1994. Homologous and heterologous regulation of α-melanocyte stimulating hormone receptors in human and mouse melanoma cell lines. Cancer Res 54:2604-2610.
    • (1994) Cancer Res , vol.54 , pp. 2604-2610
    • Sigegrist, W.1    Stutz, S.2    Eberle, A.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.