VEGF/VPF overexpression in skin of transgenic mice induces angiogenesis, vascular hyperpermeability and accelerated tumor development

Oncogene

Volumn 17, Issue 3, 1998, Pages 303-311

  Larcher, Fernando ^a   Murillas, Rodolfo ^a,c   Bolontrade, Marcela ^b   Conti, Claudio J ^b   Jorcano, José L ^a  

^a CIEMAT   (Spain)

^b UNIVERSITY OF TEXAS   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Angiogenesis; Epidermis; Skin carcinogenesis; Transgenic mice

Indexed keywords

VASCULOTROPIN;

ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; EMBRYO; ERYTHEMA; FEMALE; GENE INDUCTION; HISTOPATHOLOGY; MALE; MOUSE; NONHUMAN; ONCOGENE H RAS; PAPILLOMA; PRIORITY JOURNAL; PROMOTER REGION; SKIN; SKIN BLOOD FLOW; SKIN CARCINOGENESIS; SKIN EDEMA; TRANSGENIC MOUSE;

ANIMALIA; MUS MUSCULUS;

EID: 0032560844     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1201928     Document Type: Article

References (58)

1. Aldaz CM, Conti CJ, Klein-Szanto AJP and Slaga TJ. (1987). Proc. Natl. Acad. Sci. USA, 84, 2029-2032.
2. Aldaz CM, Conti CJ, Larcher F, Trono D, Roop DR, Chesner J, Whitehead T and Slaga TJ. (1988). Cancer Res., 48, 3253-3257.
3. Arbiser JL, Moses MA, Fernandez CA, Ghiso N, Cao Y, Klauber N, Frank D, Brownlee M, Flynn E, Parangi S, Byers HR and Folkman J. (1997). Proc. Natl. Acad. Sci. USA, 94, 861-866.
4. Ballaun C, Weninger W, Uthman A, Weich H and Tschachler E. (1995). J. Invest. Dermatol., 104, 7-10.
5. Beck Jr, L and D'Amore PA. (1997). FASEB J., 11, 365-373.
6. Blessing M, Zentgraft H and Jorcano JL. (1987) EMBO J., 6, 567-575.
7. Breier G, Albrecht U, Sterrer S, and Risau W. (1992). Development, 114, 521-532.
8. Brown LF, Yeo K-T, Berse B, Senger DR, Dvorak HF and Van de Water L. (1992). J. Exp. Med., 176, 1375-1379.
9. Brown LF, Harrist TJ, Yeo K-T, Stale-Bäckdahl M, Jackman RW, Berse B, Tognazzi K, Dvorak HF and Detmar M. (1995). J. Invest. Dermatol., 104, 744-749.
10. Cano A, Gamallo C, Kemp C, Benito N, Palacios J, Quintanilla M and Balmain A. (1996). Int. J. Cancer, 65, 254-262.
11. Carmeliet P, Ferreira V, Breier G, Pollefeyt S, Kiecksens L, Gersenstein M, Fahrig M, Vandenhoeck A, Harpal K, Eberhardt C, Declercq C, Pawling J, Moons L, Collen D, Risau W and Nagy A. (1996). Nature, 380, 435-439.
12. Chomczynski P and Sacchi N. (1987). Analytical Biochem., 162, 156-159.
13. Cui W, Fowlis D, Bryson S, Duffie E, Ireland H, Ballmain A and Akhurst R. (1996). Cell, 86, 531-542.
14. Detmar M, Brown LF, Claffey KP, Yeo T-K, Kocher O, Jackman RW, Berse B and Dvorak HF. (1994). J. Exp. Med., 180, 1141-1146.
15. Detmar M, Yeo K-T, Nagy JA, Van de Water L, Brown LF, Berse B, Elicker BM, Ledbetter S and Dvorak HF. (1995) J. Invest. Dermatol., 105, 44-50.
16. Detmar M. (1996). J. Invest. Dermatol., 106, 207-208.
17. Ferrara N, Carver-Moore K, Chen H, Dowd, M, Lu L, O'Shea KS, Powell-Braxton L, Hillan KJ and Moore MW. (1996). Nature, 380, 389-442.
18. Ferrara N. (1996). Eur. J. Cancer, 32A, 2143-2422.
19. Flamme I, von Reutern M, Drexler HCA, Syed-Ali S and Risau W. (1995). Devel. Biol., 171, 399-414.
20. Folkman J. (1995). Nature Med., 1, 27-31.
21. Fong GH, Rossant J, Gertsenstein M and Breitman ML. (1995). Nature, 376, 66-70.
22. Fowlis D, Cui W, Johnson SA, Balmain A and Akhurst RJ. (1996). Cell Growth Differ., 3, 81-91.
23. Frank S., Hubner G, Breier G, Longaker MT, Greenhalgh DG, and Werner S. (1995). J. Biol. Chem., 270, 12607-12613.
24. Gimenez-Conti I, Aldaz CM, Bianchi AB, Roop DR, Slaga TJ, Conti CJ. (1990). Carcinogenesis, 11, 1995-1999.
25. Goldberg MA and Schneider TJ. (1994). J. Biol. Chem., 269, 4355-4359.
26. Gomez M, Navarro P, Quintanilla M and Cano A. (1992). Exp Cell Res., 201, 250-261.
27. Grugel S, Finkenzeller G, Weindel K, Barleon B and Marme D. (1995). J. Biol. Chem., 270, 25915-25919.
28. Hannahan D and Folkman J. (1996). Cell, 86, 353-364.
29. Hansen LA and Tennant RW. (1994). Proc. Natl. Acad. Sci. USA, 91, 7822-7826.
30. Hogan B, Constantini F and Lacy E. (1986). Manipulating the mouse embryo, a laboratory manual. Cold Spring Harbour Laboratory (ed), Cold Spring Harbour, USA.
31. Houck H, Ferrara N, Winer J, Cachianes G, Li B and Leung DW. (1991). Mol. Endocrinol., 5, 1806-1814.
32. Jeltsch M, Kaipainen A, Joukov V., Meng X, Lakso M, Ruvala H, Swartz M, Fukumura D, Jain RK and Alitalo K. (1997). Science, 276, 1423-1425.
33. Joukov V, Sorsa T, Kumar V, Jeltsch M, Claesson-Welsh L, Cao Y, Saksela O, Kalkkinen N and Alitalo K. (1997). EMBO J., 13, 3898-3911.
34. Klagsbrun M and D'Amore PA. (1996). Cytokine Growth Factor Rev, 7, 259-270.
35. Larcher F, Robles A., Duran H, Murillas R, Cano A, Quintanilla M, Conti CJ and Jorcano JL. (1996). Cancer Res., 56, 5391-5396.
36. Leder A, Kuo A, Cardiff R, Sinn E and Leder P. (1990). Proc. Natl Acad. Sci. USA, 87, 9178-9182.
37. Malhotra R, Stenn KS, Fernandez LA and Braverman IM. (1989). Lab. Invest., 61, 162-165.
38. Matthews W, Jordan CT, Gavin M, Jenkins NA, Copeland NG and Lemischka IR. (1991). Proc. Natl. Acad. Sci. USA, 88, 9026-9030.
39. Morbidelli L, Birkenhaeger R, Roeckl W, Granger HJ, Kaerst U, Weich HA and Ziehe M. (1998). Angiogeneis, 1, In press.
40. Mukhopadhyay D, Tsiokas L, Zhou XM, Foster D, Brugge JS, Sukhatme VP. (1995). Nature, 375, 577-581.
41. Murillas R, Larcher F, Conti CJ, Santos M, Ullrich A, Jorcano JL. (1995). EMBO J., 14, 5216-5223.
42. Nischt R, Roop DR, Mehrel T, Yuspa SH, Rentrop M, Winter H, Schweizer J. (1988) Mol. Carcinog., 1, 96-108.
43. Rak J, Mitsuhashi Y, Bayko L, Filmus J, Shrisawa T and Kerbel RS. (1995). Cancer Res., 55, 4575-4580.
44. Ramirez A, Vidai MA, Bravo A, Larcher F and Jorcano JL. (1995). Proc. Natl. Acad. Sci. USA, 92, 4783-4787.
45. Ramirez A, Vidai MA, Bravo A and Jorcano JL. (1998). DNA and Cell Biol., 17, 177-185.
46. Risau W. (1997). Nature, 386, 671-674.
47. Robles AI, Larcher F, Whalin RB, Murillas R, Richie E, Gimenez-Conti IB, Jorcano JL and Conti CJ. (1996). Proc. Natl. Acad. Sci. USA, 93, 7634-7638.
48. Saez E, Rutberg SH, Mueller E, Oppenheim H, Smoluk J, Yuspa SH and Spiegelman BM. (1995). Cell, 82, 721-732.
49. Schweizer J. (1993). Molecular biology of Skin: The keratinocyte. Darmon M and Blumemberg M (eds). Academic Press, pp. 33-78.
50. Shweiki D, Itin A, Doffer D and Keshet E. (1992). Nature, 359, 843-845.
51. Skobe M, Rockwell P, Goldstein N, Vosseler S and Fusenig N. (1997). Nature Med., 3, 1222-1227.
52. Smith-McCune K, Zhu Y-H, Hannahan D and Arbeit J. (1997). Cancer Res., 57, 1294-1300.
53. Smola H, Thiekötter G and Fusenig N. (1993). J. Cell Biol., 122, 417-429.
54. Spalding JW, Momma J, Elwell MR and Tennant RW. (1993). Carcinogenesis, 14, 1335-1341.
55. Tennenbaum T, Weiner AK, Belanger AJ, Glick AB, Hennings H and Yuspa SH.( 1993). Cancer Res., 53, 4803-4810.
56. Wang XJ, Greenhalgh DA, Lu XR, Bickenbach JR and Roop DR. (1995). Oncogene 10, 279-289.
57. Woodroofe C, Müller W and Rüther U. (1992). DNA and Cell Biol., 11, 587-592.
58. Yuspa SH. (1994). Cancer Res., 54, 1178-1189.