Serine proteinase inhibitors in the skin: Role in homeostasis and disease

Current Protein and Peptide Science

Volumn 6, Issue 3, 2005, Pages 241-254

  Mägert, Hans Jürgen ^a   Drögemüller, Katrin ^b   Raghunath, Michael ^c,d  

^a ANHALT UNIVERSITY OF APPLIED SCIENCES   (Germany)

^b IPF PHARMACEUTICALS GMBH   (Germany)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Atopic dermatitis; Kallikreins; Keratinocytes; LEKTI; Netherton syndrome; Psoriasis; SPINK5

Indexed keywords

BERINERT; CHYMASE; COMPLEMENT COMPONENT C1S INHIBITOR; ELAFIN; LYMPHOEPITHELIAL KAZAL TYPE RELATED INHIBITOR; MASPIN; PLASMINOGEN ACTIVATOR INHIBITOR 2; PROTEASE INHIBITOR 13; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; SQUAMOUS CELL CARCINOMA ANTIGEN; SQUAMOUS CELL CARCINOMA ANTIGEN 1; SQUAMOUS CELL CARCINOMA ANTIGEN 2; ULINASTATIN; UNCLASSIFIED DRUG;

ANGIONEUROTIC EDEMA; ATOPIC DERMATITIS; CELL DIFFERENTIATION; CELL PROLIFERATION; DRUG TARGETING; HOMEOSTASIS; HUMAN; KERATINOCYTE; LEUKOCYTE ACTIVATION; MEDICAL RESEARCH; NETHERTON DISEASE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEINASE INHIBITION; PSORIASIS; REVIEW; SKIN CANCER; SKIN DISEASE; SKIN INFLAMMATION; SKIN PROTECTION;

CELL DIFFERENTIATION; CELL PROLIFERATION; DERMATITIS; DERMATITIS, ATOPIC; HOMEOSTASIS; HUMANS; KERATINOCYTES; MODELS, BIOLOGICAL; PSORIASIS; SERINE PROTEINASE INHIBITORS; SKIN; SKIN DISEASES;

EID: 20444446698     PISSN: 13892037     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389203054065374     Document Type: Review

References (174)

1. Vanaman, T.C. and Bradshaw, R.A. (1999) J. Biol. Chem., 274, 20047.
2. Nagase, H. and Woessner, J.F. (1999) J. Biol. Chem., 274, 21491-21494.
3. Wolf, B.B. and Green, D.R. (1999) J. Biol. Chem., 274, 20049-20052.
4. Neurath, H. (1984) Science, 224, 350-357.
5. Southan, C. (2000) J. Pept. Sci., 6, 453-458.
6. Bode, W. and Huber, R. (1992) Eur. J. Biochem., 204, 433-451.
7. Roberts, R.M., Mathialagan, N., Duffy, J.Y. and Smith, G.W. (1995) Crit. Rev. Eukaryot. Gene Expr., 5, 385-436.
8. Otlewski, J., Krowarsch, D. and Apostoluk, W. (1999) Acta Biochim. Pol., 46, 531-565.
9. Bode, W. and Huber, R. (2000) Biochim. Biophys. Acta, 1477, 241-252.
10. Rawlings, N.D., Tolle, D.P. and Barrett, A.J. (2004) Biochem. J., 378, 705-716.
11. Fritz, H. (1980) In Protein Degradation in Health and Disease, Excerpta Medica (Ciba Foundation, Symposium 1975). pp. 351-379.
12. Hautamaki, R.D., Kobayashi, D.K., Senior, R.M. and Shapiro, S.D. (1997) Science, 277, 2002-2004.
13. Eckert, R.L., Crish, J.F. and Robinson, N.A. (1997) Physiol. Rev., 77, 397-424.
14. Algermissen, B., Sitzmann, J., Nurnberg, W., Laubscher, J.C., Henz, B.M. and Bauer, F. (2000) Arch. Dermatol. Res., 292, 488-495.
15. Hibino, T., Matsuda, Y., Takahashi, T. and Goetnick, P.F. ( 1999) J. Invest. Dermatol., 112, 85-90.
16. Steinhoff, M., Corvera, C.U., Thoma, M.S., Kong, W., McAlpine, B.E., Caughey, G.H., Ansel, J.C. and Bunnett, N.W. (1999) Exp. Dermatol., 8, 282-294.
17. Schechter, N.M., Brass, L.F., Lavker, R.M. and Jensen, P.J. (1998) J. Cell Physiol., 176, 365-373.
18. Derian, C.K., Eckardt, A.J. and Andrade-Gordon, P. (1997) Cell Growth Differ., 8, 743-749.
19. Akers, I.A., Parsons, M., Hill, M.R., Hollenberg, M.D., Sanjar, S., Laurent, G.J. and McAnulty, R.J. (2000) Am. J. Physiol. Lung Cell. Mol. Physiol., 278, L193-L201.
20. Frungieri, M.B., Weidinger, S., Meineke, V., Köhn, F.M. and Meyerhofer, A. (2002) Proc. Natl. Acad. Sci. USA, 99, 15072-15077.
21. Rogalski, C., Meyer-Hoffert, U., Proksch, E. and Wiedow, O. (2002) J. Invest. Dermatol., 118, 49-54.
22. Briggaman, R.A., Schechter, N.M., Fräki, J. and Lazarus, G.S. (1984) J. Exp. Med., 160, 1027-1042.
23. Egelrud, T. (1993) J. Invest. Dermatol., 101, 200-204.
24. Hansson, L., Stromqvist, M., Backman, A., Wallbrandt, P., Carlstein, A. and Egelrud, T. (1994) J. Biol. Chem., 269, 19420-19426.
25. Brattsand M. and Egelrud, T. (1999) J. Biol. Chem., 274, 30033-30040.
26. Harvey, T.J., Hooper, J.D., Myers, S.A., Stephenson, S.A., Ashworth, L.K. and Clements, J.A. (2000) J. Biol. Chem., 275, 37397-37406.
27. Diamandis, E.P., Yousef, G.M., Clements, J., Ashworth, L.K., Yoshida, S., Egelrud, T., Nelson, P.S., Shiosaka, S., Little, S., Lilja, H., Stenman, U.H., Rittenhouse, H.G. and Wain, H. (2000) Clin. Chem., 46, 1855-1858.
28. Lundström, A., Serre, G., Haftek, M. and Egelrud, T. ( 1994) Arch. Dermatol. Res., 286, 369-375.
29. Simon, M., Montezin, M., Guerrin, M., Durieux, J.J. and Serre, G. (1997)) J. Biol. Chem., 272, 31770-31776.
30. Simon, M., Jonca, N., Guerrin, M., Haftek, M., Bernard, D., Caubet, C., Egelrud, T., Schmidt, R. and Serre, G. (2001) J. Biol. Chem., 276, 20292-20299.
31. Egelrud, T. (2000) Acta Derm. Venereol., 208, 44-45.
32. Komatsu, N., Takata, M., Otsuki, N., Toyama, T., Ohka, R., Takehara, K. and Saijoh, K. (2003) J. Invest. Dermatol., 121, 542-549.
33. Arnemann, J., Sullivan, K.H., Magee, A.I., King, I.A. and Buxton, R.S. (1993) J. Cell Sci., 104, 741-750.
34. Liu, Z., Shapiro, S.D., Zhou, X., Twining, S.S., sen., R.M., Giudice, G.J., Fairley, J.A. and Diaz, L.A. (2000) J. Clin. Invest., 105, 113-123.
35. Liu, Z., Diaz, L.A., Troy, J.L., Taylor, A.F., Emery, D.J., Fairley, J.A. and Giudice, G.J. (1993) J. Clin. Invest., 92, 2480-2488.
36. Thornberry, N.A., Bull, H.G., Calaycay, J.R., Chapman, K.T., Howard, A.D., Kostura, M.J., Miller, D.K., Molineaux, S.M., Weidner, J.R., Aunins, J., Elliston, K.O., Ayala, J.M., Casano, F.J., Chin, J., Ding, G.J.-F., Egger, L.A., Gaffney, E.P., Limjuco, G., Palyha, O.C., Raju, S.M., Rolando, A.M., Salley, J.P., Yamin, T.T., Lee, T.D., Shively, J.E., MacCross, M., Mumford, R.A., Schmidt, J.A. and Tocci M.J. (1992) Nature, 356, 768-774.
37. Mizutani, H., Schechter, N., Lazarus, G., Black, R.A. and Kupper, T.S. (1991) J. Exp. Med., 174, 821-825.
38. Nylander-Lundqvist, E. and Egelrud, T. (1997) Acta Derm. Venereol., 77, 203-206.
39. Coeshott, C., Ohnemus, C., Pilyavskaya, A., Ross, S., Wieczorek, M., Kroona, H., Leimer, A.H. and Cheronis, J. (1999) Proc. Natl. Acad. Sci. USA, 96, 6261-6266.
40. Brattsand, M. and Egelrud, T. (1998) Cytokine, 10, 506-513.
41. Vakili, J., Ständker, L., Detheux, M., Vassart, G., Forssmann, W.G. and Parmentier, M. (2001) J. Immunol., 167, 3406-3413.
42. Detheux, M., Ständker, L., Vakili, J., Münch, J., Forssmann, U., Adermann, K., Pohlmann, S., Vassart, G., Kirchhoff, F., Parmentier, M. and Forssmann, W.G. (2000) J. Exp. Med., 192, 1501-1508.
43. Vergnolle, N., Wallace, J.L., Bunnett, N.W. and Hollenberg, M.D. (2001) Trends Pharmacol. Sci., 22, 146-152.
44. Macfarlane, S.R., Seatter, M.J., Kanke, T., Hunter, G.D. and Plevin, R. (2001) Pharmacol. Rev., 53, 245-282.
45. Hollenberg, M.D. and Compton, S.J. (2002) Pharmacol. Rev., 54, 203-217.
46. Vergnolle, N. (1999) J. Immunol., 163, 5064-5069.
47. Miike, S., McWilliam, A.S. and Kita, H. (2001) J. Immunol., 167, 6615-6622.
48. Seeliger, S., Derian, C.K., Vergnolle, N., Bunnett, N.W., Nawroth, R., Schmelz, M., Von Der Weid, P.Y., Buddenkotte, J., Sunderkötter, C., Metze, D., Andrade-Gordon, P., Harms, E., Vestweber, D., Luger, T.A. and Steinhoff, M. (2003) FASEB J., 17, 1871-1885.
49. Allen, A., Siegfried, E., Silverman, R., Williams, M. L., Elias, P. M., Szabo, S. K., and Korman, N. J. (2001) Arch. Dermatol., 137, 747-750.
50. Heinzel, R., Appelhans, H., Gassen, G., Seemüller, U., Machleidt, W., Fritz, H. and Steffens, G. (1986) Eur. J. Biochem., 160, 61-67.
51. Seemüller, U., Arnhold, M., Fritz, H., Wiedenmann, K., Machleidt, W., Heinzel, R., Appelhans, H., Gassen, H.G. and Lottspeich, F. (1986) FEBS Lett., 199, 43-48.
52. Ohlsson, M., Fryksmark, U., Polling, A., Tegner, H. and Ohlsson, K. (1984) Acta Otolaryngol., 98, 147-151.
53. Pillay, K., Coutsoudis, A., Agadzi-Naqvi, A.K., Kuhn, L., Coovadia, H.M. and Janoff, E.N. (2001) J. Infect. Dis., 183, 653-656.
54. Wingens, M., van Bergen, B.H., Hiemstra, P.S., Meis, J.F., van Vlijmen-Willems, I.M., Zeeuwen, P.L., Mulder, J., Kramps, H.A., van Ruissen, F. and Schalkwijk, J. (1998) J. Invest. Dermatol., 111, 996-1002.
55. Seemüller, U., Arnhold, M., Fritz, H., Wiedenmann, K., Machleidt, W., Heinzel, R., Appelhans, H., Gassen, H.G. and Lottspeich, F. (1986) FEBS Lett., 199, 43-48.
56. Thompson, R.C. and Ohlsson, K. (1986) Proc. Natl. Acad. Sci. USA, 83, 6692-6696.
57. Fink, E., Nettelbeck, R. and Fritz, H. (1986) Biol. Chem. Hoppe Seyler, 367, 567-571.
58. Franzke, C.W., Baici, A., Bartels, J., Christophers, E. and Wiedow, O. (1996) J. Biol. Chem., 271, 21886-21890.
59. Ashcroft, G.S., Lei, K., Jin, W., Longenecker, G., Kulkarni, A.B., Greenwell-Wild, T., Hale-Donze, H., McGrady, G., Song, X.-Y. and Wahl, S.M. (2000) Nat. Med., 6, 1147-1153.
60. Zhu, J., Nathan, C., Jin, W., Sim, D., Ashcroft, G.S., Wahl, S.M., Lacomis, L., Erdjument-Bromage, H., Tempst, P., Wright, C.D. and Ding, A. (2002) Cell, 111, 867-878.
61. Schalkwijk, J., Chang, A., Janssen, P., De Jongh, G.J. and Mier, P.D. (1990) Br. J. Dermatol., 122, 631-641.
62. Wiedow, O., Schröder, J.M., Gregory, H., Young, J.A. and Christophers, E. (1990) J. Biol. Chem., 265, 14791-14795.
63. Alkemade, J.A., Molhuizen, H.O., Ponec, M., Kempenaar, J.A., Zeeuwen, P.L., de Jongh, G.J., van Vlijmen-Willems, I.M., van Erp, P.E., van de Kerkhof, P.C. and Schalkwijk, J. (1994) J. Cell Sci., 107, 2335-2342.
64. Pfundt, R., van Ruissen, F., van Vlijmen-Willems, I.M., Alkemade, H.A., Zeeuwen, P.L., Jap, P.H., Dijkman, H., Fransen, J., Croes, H., van Erp, P.E. and Schalkwijk, J. (1996) J. Clin. Invest., 15, 1389-1399.
65. Tanaka, N., Fujioka, A., Tajima, S., Ishibashi, A. and Hirose, S. (2000) Br. J. Dermatol., 143, 728-732.
66. Lee, S.K., Lee, S.S., Hirose, S., Park, S.C., Chi, J.G., Chung, S.I. and Mori, M. (2002) Histochem. Cell Biol., 117, 423-430.
67. Alkemade, H.A., Molhuizen, H.O., van Vlijmen-Willems, I.M., van Haelst, U.J. and Schalkwijk, J. (1993) Am. J. Pathol., 143, 1679-1687.
68. Yamamoto, S., Egami, H., Kurizaki, T., Ohmachi, H., Hayashi, N., Okino, T., Shibata, Y., Schalkwijk, J. and Ogawa, M. (1997) Br. J. Cancer, 76, 1081-1086.
69. Yoshida, N., Egami, H., Yamashita, J., Takai, E., Tamori, Y., Fujino, N., Kitaoka, M., Schalkwijk, J. And Ogawa, M. (2002) Oncol. Rep., 9, 495-501.
70. Schalkwijk, J., Wiedow, O. and Hirose, S. (1999) Biochem. J., 340, 569-577.
71. Nakane, H., Ishida-Yamamoto, A., Takahashi, H. and Iizuka, H. (2002) J. Invest. Dermatol., 119, 50-55.
72. Schalkwijk, J., de Roo, C. and de Jongh, G.J. (1991) Biochim. Biophys. Acta, 1096, 148-154.
73. Schalkwijk, J., van Vlijmen, I.M., Alkemade, J.A. and de Jongh G.J. (1993) J. Invest. Dermatol., 100, 390-933.
74. Nonomura, K., Yamanishi, K., Yasuno, H., Nara, K. and Hirose, S. (1994) J. Invest. Dermatol., 103, 88-91.
75. Streit, V., Wiedow, O., Bartels, J. and Christophers, E. ( 1995) J. Invest. Dermatol., 105, 562-566.
76. Le, T.K., Schalkwijk, J., van de Kerkhof, P.C., van Haelst, U. and van der Valk, P.G. (1998) Am. J. Contact Dermat., 9, 23-28.
77. Alkemade, H.A., de Jongh, G.J., Arnold, W.P., van de Kerkhof, P.C. and Schalkwijk, J. (1995) J. Invest. Dermatol., 104, 189-193.
78. Ying, Q.L. and Simon, S.R. (2001) Am. J. Respir. Cell Mol. Biol. 24, 83-89.
79. Vachon, E., Bourbonnais, Y., Bingle, C.D., Rowe, S.J., Janelle, M.F. and Tremblay, G.M. (2002) Biol. Chem., 383, 1249-1256.
80. Sallenave, J.M. (2002) Biochem. Soc. Trans., 30, 111-115.
81. Sallenave J.M. (2000) Respir. Res., 1, 87-92.
82. Xu, Y., Carr, P.D., Guss, J.M. and Ollis, D.L. (1998) J. Mol. Biol., 276, 955-966.
83. Vetr, H. and Gebhard, W. (1990) Biol. Chem. Hoppe Seyler, 371, 1185-1196.
84. Salier, J.P., Rouet, P., Raguenez, G. and Daveau, M. (1996) Biochem. J., 315, 1-9.
85. Ide, H., Itoh, H., Yoshida, E., Kobayashi, T., Tomita, M., Maruyama, H., Osada, Y., Nakahata, T. and Nawa, Y. (1999) Cell Tissue Res., 297, 149-154.
86. Aubry, M. and Bieth, J. (1976) Biochim. Biophys. Acta, 438, 221-230.
87. Albrecht, G.J., Hochstrasser, K. and Salier, J.P. (1983) Hoppe Seyler's Z. Physiol. Chem., 364, 1703-1708.
88. Pratt, C.W. and Pizzo, S.V. (1987) Biochemistry, 26, 2855-2863.
89. Potempa, J., Kwon, K., Chawla, R. and Travis, J. (1989) J. Biol. Chem., 264, 15109-15114.
90. Kato, H. and Torigoe, T. (1977) Cancer, 40, 1621-1628.
91. Barnes, R.C. and Worrall, D. M. (1995) FEBS Lett., 373, 61-65.
92. Schick, C., Kamachi, Y., Bartuski, A.J., Cataltepe, S., Schechter, N.M., Pemberton, P.A. and Silverman, G. A. (1997) J. Biol. Chem., 272, 1849-1855.
93. Cataltepe, S., Gornstein, E.R., Schick, C., Kamachi, Y., Chatson, K., Fries, J. and Silverman G.A. (2000) J. Histochem. Cytochem., 48, 113-122.
94. Zou, Z., Anisowicz, A., Hendrix, M.J.C., Thor, A., Neveu, M., Sheng, S., Rafidi, K., Seftor, E. and Sager, R. (1994) Science, 263, 526-529.
95. Ngamkitidechakul, C., Burke, J.M., O'Brien, W.J. and Twining, S.S. (2001) Invest. Ophthal. Vis. Sci., 42: 3135-3141.
96. Bass, R., Fernandez, A.M. and Ellis, V. (2002) J. Biol. Chem., 277, 46845-46848.
97. Reis-Filho, J.S., Torio, B., Albergaria, A. and Schmitt, F.C. (2002) Virchow's Arch., 441, 551-558.
98. Abts, H.F., Welss, T., Mirmohammadsadegh, A., Kohrer, K., Michel, G. and Ruzicka, T. (1999) J. Mol. Biol., 293, 29-39.
99. Abts, H.F., Breuhahn, K., Michel, G., Kohrer, K., Esser, P. and Ruzicka, T. (1997) Photochem. Photobiol., 66, 363-367.
100. Welss, T., Sun, J., Irving, J.A., Blum, R., Smith, A.I., Whisstock, J.C., Pike, R.N., von Mikecz, A., Ruzicka, T., Bird, P.I. and Abts, H.F. (2003) Biochemistry, 42, 7381-7389.
101. Antalis, T.M., Clark, M.A., Barnes, T., Lehrbach, P.R., Devine, P.L., Schevzov, G., Goss, N.H., Stephens, R.W. and Tolstoshev, P. (1988) Proc. Natl. Acad. Sci. USA, 85, 985-989.
102. Kruithof, E.K.O., Baker, M.S. and Bunn, C.L. (1995) Blood 86, 4007-4024.
103. Dickinson, J.L., Bates, E.J., Ferrante, A. and Antalis, T.M. (1995) J. Biol. Chem., 270, 27894-27904.
104. Dougherty, K.M., Pearson, J.M., Yang, A.Y., Westrick, R.J., Baker, M.S. and Ginsburg, D. (1999) Proc. Natl. Acad. Sci. USA, 96, 686-691.
105. Zhang, Q., Wu, Y., Ann, D.K., Messadi, D.V., Tuan, T.L., Kelly, A.P., Bertolami, C.N. and Le, A.D. (2003) J. Invest. Dermatol., 121, 1005-1012.
106. Davis, A.E. 3rd, Whitehead, A.S., Harrison, R.A., Dauphinais, A., Bruns, G.A.P., Cicardi, M. and Rosen, F.S. (1986) Proc. Natl. Acad. Sci. USA, 83, 3161-3165.
107. Davis, A.E. 3rd., Aulak, K., Parad, R.B., Stecklein, H.P., Eldering, E., Hack, C.E., Kramer, J., Strunk, R.C., Bissler, J. and Rosen, F.S. (1992) Nat. Genet., 1, 354-358.
108. Cicardi, M. and Agostoni, A. (1996) New Engl. J. Med., 334, 1666-1667.
109. Mägert, H.J., Ständker, L., Kreutzmann, P., Zucht, H.D., Reinecke, M., Sommerhoff, C.P., Fritz, H. and Forssmann, W.G. ( 1999) J. Biol. Chem., 274, 21499-21502.
110. Walden, M., Kreutzmann, P., Drögemüller, K., John, H., Forssmann, W.G. and Mägert, H.J. (2002) Biol. Chem., 383, 1139-1141.
111. Kreutzmann, P., Schulz, A., Ständker, L., Forssmann, W.G. and Mägert, H.J. (2004) J. Chromatogr. B, 803, 75-81.
112. Lauber, T., Schulz, A., Schweimer, K., Adermann, K. and Marx, U.C. (2003) J. Mol. Biol., 328, 205-219.
113. Komatsu, N., Takata, M., Otsuki, N., Ohka, R., Amano, O., Takehara, K. and Saijoh, K. (2002) J. Invest. Dermatol., 118, 436-443.
114. Mägert, H.J., Kreutzmann, P., Ständker, L., Walden, M., Drögemüller, K. and Forssmann, W.G. (2002) Int. J. Biochem. Cell Biol., 34, 573-576.
115. Bitoun, E., Micheloni, A., Lamant, L., Bonnart, C., Tartaglia-Polcini, A., Cobbold, C., Al Saati, T., Mariotti, F., Mazereeuw-Hautier, J., Boralevi, F., Hohl, D., Harper, J., Bodemer, C., D'Alessio, M. and Hovnanian, A. (2003) Hum. Mol. Genet, 12, 2417-2430.
116. Ahmed, A., Kandola, P., Ziada, G. and Parenteau, N. (2001) J. Protein Chem., 20, 273-278.
117. Chavanas, S., Bodemer, C., Rochat, A., Hamel-Teillac, D., Ali, M., Irvine, A.D., Bonafe, J.L., Wilkinson, J., Taieb, A., Barrandon, Y., Harper, J.I., de Prost, Y. and Hovnanian, A. (2000) Nat. Genet., 25, 141-142.
118. Mägert, H.J., Kreutzmann, P., Drögemüller, K., Ständker, L., Adermann, K., Walden, M., John, H., Korting, H.C. and Forssmann, W.G. (2002) Eur. J. Med. Res., 7, 49-56.
119. Raghunath, M., Tontsidou, L., Oji, V., Aufenvenne, K., Schürmeyer-Horst, F., Jayakumar, A., Ständer, H., Smolle, J., Clayman, G.L. and Traupe, H. (2004) , J. Invest. Dermatol., 123, 474-483.
120. Egelrud, T., Brattsand, M., Kreutzmann, P., Walden, M., Vitzithum, K., Marx, U.C., Forssmann, W.G. and Mägert, H.J. Brit. J. Dermatol. (submitted).
121. Mitsudo, K., Jayakumar, A., Henderson, Y., Frederick, M.J., Kang, Y., Wang, M., El-Naggar, A.K. and Clayman, G.L. (2003) Biochemistry, 42, 3874-3881.
122. Jayakumar, A., Kang, Y., Mitsudo, K., Henderson, Y., Frederick, M.J., Wang, M., El-Naggar, A.K., Marx, U.C., Briggs, K. and Clayman, G.L. (2004) Protein Expr. Purif., 35, 93-101.
123. Traupe, H. (1989) In The Ichthyoses. A Guide to Clinical Diagnosis, Genetic Counseling, and Therapy (Traupe, H., Ed.). pp. 168-178. Springer Verlag, Berlin.
124. Ahuja, A., Land, K. and Barnes, C.J. (2003) South. Med. J., 96, 1068-1072.
125. Leung, D.Y., Boguniewicz, M., Howell, M.D., Nomura, I. and Hamid, Q.A. (2004) J. Clin. Invest., 113, 651-657.
126. Greene, S.L. and Muller, S.A. (1985) J. Am. Acad. Dermatol., 13, 329-37.
127. Comèl, M. (1949) Dermatologica, 98, 133-136.
128. Netherton, E.W. (1958) Arch. Dermatol., 78, 483-487.
129. Judge, M.R., Morgan, G. and Harper, J.I. (1994) Br. J. Dermatol., 131, 615-621.
130. Müller, F.B., Haußer, I., Berg, D., Casper, C., Maiwald, R., Jung, A., Jung, H. and Korge, B.P. (2002) Br. J. Dermatol., 146, 495-499.
131. Sprecher, E., Chavanas, S., DiGiovanna, J.J., Amin, S., Nielsen, K., Prendiville, J.S., Silverman, R., Esterly, N.B., Spraker, M.K., Guelig, E., de Luna, M.L., Williams, M.L., Buehler, B., Siegfried, E.C., Van Maldergem, L., Pfendner, E., Bale, S.J., Uitto, J., Hovnanian, A. and Richard, G. (2001) J. Invest. Dermatol., 117, 179-187.
132. Bitoun, E., Chavanas, S., Irvine, A.D., Lonie, L., Bodemer, C., Paradisi, M., Hamel-Teillac, D., Ansai, S., Mitsuhashi, Y., Taieb, A., de Prost, Y., Zambruno, G., Harper, J.I. and Hovnanian, A. (2002) J. Invest. Dermatol., 118, 352-361.
133. Bitoun, E., Bodemer, C., Amiel, J., de Prost, Y., Stoll, C., Calvas, P. and Hovnanian, A. (2002) Prenat. Diagn., 22, 121-126.
134. Stoll, C., Alembik, Y., Tehomakov, D., Messer, J., Heid, E., Boehm, N., Calvas, P. and Hovnanian, A. (2001) Genet. Couns., 12, 237-243.
135. Chao, S.C., Tsai, Y.M. and Lee, J.Y. (2003) J. Formos. Med. Assoc., 102, 418-423.
136. Walley, A.J., Chavanas, S., Moffatt, M.F., Esnouf, R.M., Ubhi, B., Lawrence, R., Wong, K., Abecasis, G.R., Jones, E.Y., Harper, J.I., Hovnanian, A. and Cookson, W.O. (2001) Nat. Genet., 29, 175-178.
137. Kato, A., Fukai, K., Oiso, N., Hosomi, N., Murakami, T. and Ishii, M. (2003) Br. J. Dermatol., 148, 665-669.
138. Nishio, Y., Noguchi, E., Shibasaki, M., Kamioka, M., Ichikawa, E., Ichikawa, K., Umebayashi, Y., Otsuka, F. and Arinami, T. (2003) Genes Immun., 4, 515-517.
139. Moffatt, M.F. (2004) Clin. Exp. Allergy, 34, 325-327.
140. Norgett, E.E. and Kelsell, D.P. (2002) Trends Mol. Med., 8, 7.
141. Bolton, S.J., McNulty, C.A., Thomas, R.J., Hewitt, C.R. and Wardlaw, A. J. (2003) J. Leukoc. Biol., 74, 60-68.
142. Steinhoff, M., Neisius, U., Ikoma, A., Fartasch, M., Heyer, G., Skov, P.S., Luger, T.A. and Schmelz, M. (2003) J. Neurosci., 23, 6176-6180.
143. Fartasch, M., Williams, M.L. and Elias, P.M. (1999) Arch. Dermatol., 135, 823-832.
144. Hansson, L., Bergman, A., Ny, A., Ekholm, E. and Egelrud, T. (2002) IFCC Magazine, 5, 279-283.
145. Hansson, L., Backman, A., Ny, A., Edlund, M., Ekholm, E., Ekstrand Hammarström, B., Tornell, J., Wallbrandt, P., Wennbo, H. and Egelrud, T. (2002) J. Invest. Dermatol., 118, 444-449.
146. Tomimori, Y., Tsuruoka, N., Fukami, H., Saito, K., Horikawa, C., Saito, M., Muto, T., Sugiura, N., Yamashiro, K., Sumida, M., Kakutani, S. and Fukuda, Y. (2002) Biochem. Pharmacol., 64, 1187-1193.
147. Tomimori, Y., Muto, T., Fukami, H., Saito, K., Horikawa, C., Tsuruoka, N., Saito, M., Sugiura, N., Yamashiro, K., Sumida, M., Kakutani, S. and Fukuda, Y. (2002) Lab. Invest., 82, 789-794.
148. Imada, T., Komorita, N., Kobayashi, F., Naito, K., Yoshikawa, T., Miyazaki, M., Nakamura, N. and Kondo, T. (2002) Jpn. J. Pharmacol., 90, 214-217.
149. Watanabe, N., Tomimori, Y., Saito, K., Miura, K., Wada, A., Tsudzuki, M. and Fukuda, Y. (2002) Int. Arch. Allergy Immunol., 128, 229-234.
150. Bowcock, A.M. and Cookson, W.O. (2004) Hum. Mol. Genet., 13, R43-R55.
151. Peters, B.P., Weissman, F.G. and Gill, M.A. (2000) Am. J. Health Syst. Pharm., 57, 645-659.
152. Goldblum, O.M. (2002) Skinmed., 1, 132-134.
153. Shwayder, T. and Banerjee, S. (1997) Pediatr. Dermatol., 14, 473-476.
154. De Felipe, I., Vazquez-Doval, F.J. and Vicente, J. (1997) Br. J. Dermatol., 137, 468-469.
155. Cookson, W.O., Ubhi, B., Lawrence, R., Abecasis, G.R., Walley, A.J., Cox, H.E., Coleman, R., Leaves, N.I., Trembath, R.C., Moffatt, M.F. and Harper, J.I. (2001) Nat. Genet., 27, 372-373.
156. Ekholm, E. and Egelrud, T. (1999) Arch. Dermatol. Res., 291, 195-200.
157. Hazuda, D.J., Strickler, J., Kueppers, F., Simon, P.L. and Young, P.R. (1990) J. Biol. Chem., 265, 6318-6322.
158. Black, R., Kronheim, S., Sleath, P., Greenstreet, T., Virca, G.D., March, C. and Kupper, T. (1991) Agents Actions, Suppl., 35, 85-89.
159. Kuijpers, A.L.A., Zeeuwen, P.L.J.M., de Jongh, G.J., van de Kerkhof, P.C.M., Alkemade, H.A.C. and Schalkwijk, J. (1996) Arch. Dermatol. Res., 288, 641-647.
160. Schalkwijk, J., van Vlijmen, I.M.J.J., Alkemade, J.A.C. and de Jongh, G.J. (1993) J. Invest. Dermatol., 100, 390-393.
161. Nonomura, K., Yamanishi, K., Yasuno, H., Nara, K. and Hirose, S. (1994) J. Invest. Dermatol., 103, 88-91.
162. van Bergen, B.H., Andriessen, M.P.M., Spruijt, K.I.J., van de Kerkhof, P.C.M. and Schalkwijk, J. (1996) Arch. Dermatol. Res., 288, 458-462.
163. Boelsma, E., Gibbs, S. and Ponce, M. (1998) Acta Derm. Venereol., 78, 107-113.
164. Sallenavc, J.M., Shulmann, J., Crossley, J., Jordana, M. and Gauldie, J. (1994) Am. J. Respir. Cell Mol. Biol., 11, 733-741.
165. Reid, P.T., Marsden, M.E., Cunningham, G.A., Haslett, C. and Sallenave, J.M. (1999) FEBS Lett., 457, 33-37.
166. Pol, A., Pfundt, R., Zeeuwen, P., Molhuizen, H. and Schalkwijk, J. (2003) J. Invest. Dermatol., 120, 301-307.
167. Bingle, L., Tetley, T.D. and Bingle, C.D. (2001) Am. J. Respir. Cell Mol. Biol., 25, 84-91.
168. Wiedow, O., Young, J.A., Davison, M.D. and Christophers, E. (1993) J. Invest. Dermatol., 101, 305-309.
169. Harvima, I.T., Haapanen, L., Ackermann, L., Naukkarinen, A., Harvima, R.J. and Horsmanheimo, M. (1999) Acta Derm. Venereol., 79, 98-104.
170. Roth, W., Deussing, J., Botchkarev, V.A., Pauly-Evers, M., Saftig, P., Hafner, A., Schmidt, P., Schmahl, W., Scherer, J., Anton-Lamprecht, I., von Figura, K., Pans, R. and Peters, C. (2000) FASEB J., 14, 2075-2086.
171. Tobin, J.D., Foitzik, K., Reinheckel, T., Mecklenburg, L., Botchkarev, V.A., Peters, C. and Paus, R. (2002) Am. J. Pathol., 160, 1807-1821.
172. Yang, T., Liang, D., Koch, P.J., Hohl, D., Kheradmand, F. and Overbeek, P.A. (2004) Genes Dev., 18, 2354-2358.
173. Hewett, D.R., Simons, A.L., Mangan, N.E., Jolin, H.E., Green, S.M., Fallon, P.G. and McKenzie, A.N. (2005) Hum. Mol. Genet., 14, 335-346.
174. Descargues, P., Deraison, C., Bonnart, C., Kreft, M., Kishibe, M., Ishida-Yamamoto, A., Elias, P., Barrandon, Y., Zambruno, G., Sonnenberg, A. and Hovnanian, A. (2005) Nat. Genet., 37, 56-65.