Secretory leukocyte protease inhibitor mediates non-redundant functions necessary for normal wound healing

Nature Medicine

Volumn 6, Issue 10, 2000, Pages 1147-1153

  Ashcroft, Gillian S ^a   Lei, Kejian ^a   Jin, Wenwen ^a   Longenecker, Glenn ^a   Kulkarni, Ashok B ^a   Greenwell Wild, Teresa ^a   Hale Donze, Hollie ^a   McGrady, George ^a   Song, Xiao Yu ^a   Wahl, Sharon M ^a  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELASTASE; PROTEINASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL INFECTION; BLASTOCYST; ENZYME ACTIVITY; ENZYME INHIBITION; EPITHELIUM CELL; GENE EXPRESSION; HYPOTHESIS; INFLAMMATION; LEUKOCYTE; MACROPHAGE FUNCTION; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; WOUND HEALING;

ANIMALS; CYTOKINES; FEMALE; GENE DELETION; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, MUTANT STRAINS; PANCREATIC ELASTASE; PROTEINASE INHIBITORY PROTEINS, SECRETORY; PROTEINS; SECRETORY LEUKOCYTE PEPTIDASE INHIBITOR; TRANSFORMING GROWTH FACTOR BETA; WOUND HEALING;

EID: 0033787069     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/80489     Document Type: Article

References (45)

1. The acid-stable proteinase inhibitor of human mucous secretions (HUSI-I, antileukoprotease). Complete amino acid sequence as revealed by protein and cDNA sequencing and structural homology to whey proteins and Red Sea turtle proteinase inhibitor
2. Location of the protease-inhibitory region of secretory leukocyte protease inhibitor
3. Isolation and sequence of a human gene encoding a potent inhibitor of leukocyte proteases
4. Isolation, properties, and complete amino acid sequence of human secretory leukocyte protease inhibitor, a potent inhibitor of leukocyte elastase
5. Antileukoprotease inhibits stratum corneum chymotryptic enzyme. Evidence for a regulative function in desquamation
6. Differential inhibition of mast cell chymases by secretory leukocyte protease inhibitor
7. Secretory leukocyte protease inhibitor: A human saliva protein exhibiting anti-human immunodeficiency virus 1 activity in vitro
8. Inhibition of human immunodeficiency virus type 1 infectivity by secretory leukocyte protease inhibitor occurs prior to viral reverse transcription
9. Antileukoprotease: An endogenous protein in the innate mucosal defense against fungi
10. Secretory leukocyte protease inhibitor suppresses the production of monocyte prostaglandin H synthase-2, prostaglandin E2, and matrix metalloproteinases
11. Secretory leukocyte protease inhibitor suppresses the inflammation and joint damage of bacterial cell wall-induced arthritis
12. Acid-stable proteinase inhibitors from human seminal plasma
13. Neutrophil serine proteinases and defensins in chronic obstructive pulmonary disease: Effects on pulmonary epithelium
14. Induction of SLPI (ALP/HUSI-I) in epidermal keratinocytes
15. Antileukoprotease in human skin: An antibiotic peptide constitutively produced by keratinocytes
16. Secretory leukocyte protease inhibitor: A macrophage product induced by and antagonistic to bacterial lipopolysaccharide
17. Neutrophil-mediated solubilization of the subendothelial matrix: Oxidative and nonoxidative mechanisms of proteolysis used by normal and chronic granulomatous disease phagocytes
18. Up-regulation of elastase in acute wounds of healthy aged humans and chronic venous leg ulcers are associated with matrix degradation
19. Identification of neutrophil elastase as the proteinase in burn wound fluid responsible for degradation of fibronectin
20. Topical estrogen accelerates cutaneous wound healing in aged humans associated with an altered inflammatory response
21. Degradation of fibronectin by human leukocyte elastase
22. Cathepsin-G and leukocyte elastase inactivate human tumor necrosis factor and lymphotoxin
23. Cleavage of type I collagen by human neutrophil elastase
24. Activation of MMP-9 by neutrophil elastase in an in vivo model of acute lung injury
25. Transforming growth factor type β induces monocyte chemotaxis and growth factor production
26. Transforming growth factors β1, β2, and β3 and their receptors are differentially regulated during normal and impaired wound healing
27. Inhibition of NF-κB activation and augmentation of IκBβ by secretory leukocyte protease inhibitor during lung inflammation
28. Neutralisation of TGF-β 1 and TGF-β 2 or exogenous addition of TGF-β 3 to cutaneous rat wounds reduces scarring
29. Estrogen accelerates cutaneous wound healing associated with an increase in TGF-β1 levels
30. Bidirectional regulation of macrophage function by TGF-β
31. Transforming growth factor-β activation in irradiated murine mammary gland
32. Characterization of latent TGF-β activation by murine peritoneal macrophages
33. The cutaneous microfibrillar apparatus contains latent transforming growth factor-β binding protein-1 (LTBP-1) and is a repository for latent TGF-β1
34. Human mast cell chymase and leukocyte elastase release latent transforming growth factor-β 1 from the extracellular matrix of cultured human epithelial and endothelial cells
35. Transforming growth factor-beta 1 specifically localizes in elastin during synovial inflammation: An immunoelectron microscopic study
36. Requirement for receptor-bound urokinase in plasmin-dependent cellular conversion of latent TGF-β to TGF-β
37. NK-κB and Rel proteins: Evolutionarily conserved mediators of immune responses
38. Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response
39. Transforming growth factor β 1 and its latent form binding protein-1 associate with elastic fibres in human dermis: Accumulation in actinic damage and absence in anetoderma
40. GAIPG, a repeated hexapeptide of bovine and human tropoelastin, is chemotactic for neutrophils and Lewis lung carcinoma cells
41. In vitro breakdown of gingival tissue by elastase from human polymorphonuclear leukocytes. An electron microscopic study
42. Transforming growth factor β: The good, the bad, and the ugly
43. Histophotometric estimation of volume density of collagen as an indication of fibrosis in rat liver
44. Immunohistochemical detection of active transforming growth factor-β in situ using engineered tissue
45. Oral delivery of group A streptococcal cell wall augments circulating TGF-β and suppresses streptococcal cell wall arthritis