Elevated stratum corneum hydrolytic activity in Netherton syndrome suggests an inhibitory regulation of desquamation by SPINK5-derived peptides

Journal of Investigative Dermatology

Volumn 118, Issue 3, 2002, Pages 436-443

  Komatsu, Nahoko ^a   Takata, Minoru ^a   Otsuki, Norio ^a,b   Ohka, Rie ^a   Amano, Osamu ^a   Takehara, Kazuhiko ^a   Saijoh, Kiyofumi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b Maizuru Kyousai Hospital   (Japan)

Author keywords

Carboxypeptidases; Congenital ichthyosiform erythroderma; Serine protease inhibitors; Stratum corneum trypsin like serine protease; Subtilisins

Indexed keywords

CARBOXYPEPTIDASE; MESSENGER RNA; SERINE PROTEINASE INHIBITOR;

ARTICLE; CONTROLLED STUDY; DESQUAMATION; DISEASE ASSOCIATION; EPIDERMIS; ERYTHRODERMA; GENE; GENE IDENTIFICATION; GENE MUTATION; GENE STRUCTURE; GENETIC DISORDER; GENETIC TRANSCRIPTION; GENOTYPE PHENOTYPE CORRELATION; HUMAN; ICHTHYOSIS; JAPAN; KERATINOCYTE; NETHERTON DISEASE; NONSENSE MUTATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; SERINE PROTEASE INHIBITOR KAZAL TYPE 5 GENE; SKIN CELL; SKIN PERMEABILITY; STRATUM CORNEUM;

EID: 0036125197     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0022-202x.2001.01663.x     Document Type: Article

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