Inhibition of serine proteinases plasmin, trypsin, subtilisin A, cathepsin G, and elastase by LEKTI: A kinetic analysis

Biochemistry

Volumn 42, Issue 13, 2003, Pages 3874-3881

  Mitsudo, Kenji ^a   Jayakumar, Arumugam ^a   Henderson, Ying ^a   Frederick, Mitchell J ^a   Kang, Ya'an ^a   Wang, Mary ^a   El Naggar, Adel K ^a   Clayman, Gary L ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; GENES; MOLECULAR STRUCTURE; REACTION KINETICS;

GENE ENCODES;

ENZYMES;

CATHEPSIN G; CATHEPSIN K; CATHEPSIN L; CATHEPSIN S; CHYMOTRYPSIN; CYSTEINE PROTEINASE; DISULFIDE; DITHIOTHREITOL; ELASTASE; LYMPHO EPITHELIAL KAZAL TYPE RELATED INHIBITOR; PAPAIN; PLASMIN; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; SUBTILISIN; TRYPSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; COMPETITIVE INHIBITION; CONTROLLED STUDY; DISULFIDE BOND; DRUG ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; INSECT CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN TERTIARY STRUCTURE;

ALPHA-AMYLASE; AMINO ACID SEQUENCE; ANIMALS; BACULOVIRIDAE; BASE SEQUENCE; CARRIER PROTEINS; CATHEPSINS; CELL LINE, TRANSFORMED; CHYMOTRYPSIN; DISULFIDES; DITHIOTHREITOL; DNA PRIMERS; DNA, COMPLEMENTARY; HUMANS; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; PANCREATIC ELASTASE; PLANT PROTEINS; PLASMIN; POLYMERASE CHAIN REACTION; RECOMBINANT FUSION PROTEINS; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS; SPODOPTERA; SUBTILISINS; TRYPSIN INHIBITORS;

ANIMALIA; INSECTA; UNIDENTIFIED BACULOVIRUS;

EID: 0037426357     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi027029v     Document Type: Article

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