메뉴 건너뛰기




Volumn 25, Issue 12, 2005, Pages 5282-5291

G1/S cell cycle arrest provides anoikis resistance through Erk-mediated Bim suppression

Author keywords

[No Author keywords available]

Indexed keywords

APHIDICOLIN; COMPLEMENTARY DNA; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; EPIDERMAL GROWTH FACTOR RECEPTOR; MESSENGER RNA; MIMOSINE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P16INK4A; RAF PROTEIN; APOPTOSIS REGULATORY PROTEIN; BCL 2 BINDING PROTEIN, BIM; BCL-2-BINDING PROTEIN, BIM; CARRIER PROTEIN; CDKN1A PROTEIN, HUMAN; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; ENZYME INHIBITOR; MEMBRANE PROTEIN; ONCOPROTEIN; TUMOR SUPPRESSOR PROTEIN;

EID: 20344398190     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.25.12.5282-5291.2005     Document Type: Article
Times cited : (115)

References (66)
  • 2
    • 0029657768 scopus 로고    scopus 로고
    • p21WAF1/CIP1/SDI1 is elevated through a p53-independent pathway by mimosine
    • Alpan, R. S., and A. B. Pardee. 1996. p21WAF1/CIP1/SDI1 is elevated through a p53-independent pathway by mimosine. Cell Growth Differ. 7:893-901.
    • (1996) Cell Growth Differ. , vol.7 , pp. 893-901
    • Alpan, R.S.1    Pardee, A.B.2
  • 3
    • 0033104495 scopus 로고    scopus 로고
    • Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation
    • Asada, M., T. Yamada, H. Ichijo, D. Delia, K. Miyazono, K. Fukumuro, and S. Mizutani. 1999. Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation. EMBO J. 18:1223-1234.
    • (1999) EMBO J. , vol.18 , pp. 1223-1234
    • Asada, M.1    Yamada, T.2    Ichijo, H.3    Delia, D.4    Miyazono, K.5    Fukumuro, K.6    Mizutani, S.7
  • 4
    • 0037147122 scopus 로고    scopus 로고
    • Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation
    • Biswas, S. C., and L. A. Greene. 2002. Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation. J. Biol. Chem. 277:49511-49516.
    • (2002) J. Biol. Chem. , vol.277 , pp. 49511-49516
    • Biswas, S.C.1    Greene, L.A.2
  • 5
    • 0042197268 scopus 로고    scopus 로고
    • Are p27 and p21 cytoplasmic oncoproteins?
    • Blagosklonny, M. V. 2002. Are p27 and p21 cytoplasmic oncoproteins? Cell Cycle 1:391-393.
    • (2002) Cell Cycle , vol.1 , pp. 391-393
    • Blagosklonny, M.V.1
  • 6
    • 0034618369 scopus 로고    scopus 로고
    • MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells
    • Boucher, M. J., J. Morisset, P. H. Vachon, J. C. Reed, J. Laine, and N. Rivard. 2000. MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells. J. Cell. Biochem. 79:355-369.
    • (2000) J. Cell. Biochem. , vol.79 , pp. 355-369
    • Boucher, M.J.1    Morisset, J.2    Vachon, P.H.3    Reed, J.C.4    Laine, J.5    Rivard, N.6
  • 7
    • 0029916820 scopus 로고    scopus 로고
    • Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycle
    • Boudreau, N., Z. Werb, and M. J. Bissell. 1996. Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycle. Proc. Natl. Acad. Sci. USA 93:3509-3513.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 3509-3513
    • Boudreau, N.1    Werb, Z.2    Bissell, M.J.3
  • 8
    • 0034908227 scopus 로고    scopus 로고
    • A study of death by anoikis in cultured epithelial cells
    • Bretland, A. J., J. Lawry, and R. M. Sharrard. 2001. A study of death by anoikis in cultured epithelial cells. Cell Prolif. 34:199-210.
    • (2001) Cell Prolif. , vol.34 , pp. 199-210
    • Bretland, A.J.1    Lawry, J.2    Sharrard, R.M.3
  • 10
    • 0036952736 scopus 로고    scopus 로고
    • Cyclin-dependent kinase-1: Linking apoptosis to cell cycle and mitotic catastrophe
    • Castedo, M., J. L. Perfettini, T. Roumier, and G. Kroemer. 2002. Cyclin-dependent kinase-1: linking apoptosis to cell cycle and mitotic catastrophe. Cell Death Differ. 9:1287-1293.
    • (2002) Cell Death Differ. , vol.9 , pp. 1287-1293
    • Castedo, M.1    Perfettini, J.L.2    Roumier, T.3    Kroemer, G.4
  • 11
    • 0036674501 scopus 로고    scopus 로고
    • Dissemination and growth of cancer cells in metastatic sites
    • Chambers, A. F., A. C. Groom, and I. C. MacDonald. 2002. Dissemination and growth of cancer cells in metastatic sites. Nat. Rev. Cancer 2:563-572.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 563-572
    • Chambers, A.F.1    Groom, A.C.2    MacDonald, I.C.3
  • 12
    • 0037304898 scopus 로고    scopus 로고
    • New roles for p21 and p27 cell-cycle inhibitors: A function for each cell compartment?
    • Coqueret, O. 2003. New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment? Trends Cell Biol. 13:65-70.
    • (2003) Trends Cell Biol. , vol.13 , pp. 65-70
    • Coqueret, O.1
  • 13
    • 0037603113 scopus 로고    scopus 로고
    • Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
    • Debnath, J., S. K. Muthuswamy, and J. S. Brugge. 2003. Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 30:256-268.
    • (2003) Methods , vol.30 , pp. 256-268
    • Debnath, J.1    Muthuswamy, S.K.2    Brugge, J.S.3
  • 14
    • 2342627918 scopus 로고    scopus 로고
    • Focal adhesion kinase gene silencing promotes anoikis and suppresses metastasis of human pancreatic adenocarcinoma cells
    • Duxbury, M. S., H. Ito, M. J. Zinner, S. W. Ashley, and E. E. Whang. 2004. Focal adhesion kinase gene silencing promotes anoikis and suppresses metastasis of human pancreatic adenocarcinoma cells. Surgery 135:555-562.
    • (2004) Surgery , vol.135 , pp. 555-562
    • Duxbury, M.S.1    Ito, H.2    Zinner, M.J.3    Ashley, S.W.4    Whang, E.E.5
  • 16
    • 0029972440 scopus 로고    scopus 로고
    • Cell cycle blockers mimosine, ciclopirox, and deferoxamine prevent the death of PC12 cells and postmitotic sympathetic neurons after removal of trophic support
    • Farinelli, S. E., and L. A. Greene. 1996. Cell cycle blockers mimosine, ciclopirox, and deferoxamine prevent the death of PC12 cells and postmitotic sympathetic neurons after removal of trophic support. J. Neurosci. 16:1150-1162.
    • (1996) J. Neurosci. , vol.16 , pp. 1150-1162
    • Farinelli, S.E.1    Greene, L.A.2
  • 17
    • 0028057613 scopus 로고
    • Disruption of epithelial cell-matrix interactions induces apoptosis
    • Frisch, S. M., and H. Francis. 1994. Disruption of epithelial cell-matrix interactions induces apoptosis. J. Cell Biol. 124:619-626.
    • (1994) J. Cell Biol. , vol.124 , pp. 619-626
    • Frisch, S.M.1    Francis, H.2
  • 20
    • 0036790687 scopus 로고    scopus 로고
    • IEX-1: A new ERK substrate involved in both ERK survival activity and ERK activation
    • Garcia, J., Y. Ye, V. Arranz, C. Letourneux, G. Pezeron, and F. Porteu. 2002. IEX-1: a new ERK substrate involved in both ERK survival activity and ERK activation. EMBO J. 21:5151-5163.
    • (2002) EMBO J. , vol.21 , pp. 5151-5163
    • Garcia, J.1    Ye, Y.2    Arranz, V.3    Letourneux, C.4    Pezeron, G.5    Porteu, F.6
  • 21
    • 0036594890 scopus 로고    scopus 로고
    • The role of the cyclin-dependent kinase inhibitor p21 in apoptosis
    • Gartel, A. L., and A. L. Tyner. 2002. The role of the cyclin-dependent kinase inhibitor p21 in apoptosis. Mol. Cancer Ther. 1:639-649.
    • (2002) Mol. Cancer Ther. , vol.1 , pp. 639-649
    • Gartel, A.L.1    Tyner, A.L.2
  • 23
    • 0033786378 scopus 로고    scopus 로고
    • Rb function in cell-cycle regulation and apoptosis
    • Harbour, J. W., and D. C. Dean. 2000. Rb function in cell-cycle regulation and apoptosis. Nat. Cell Biol. 2:E65-E67.
    • (2000) Nat. Cell Biol. , vol.2
    • Harbour, J.W.1    Dean, D.C.2
  • 25
    • 0030027258 scopus 로고    scopus 로고
    • Mimosine arrests the cell cycle after cells enter S-phase
    • Hughes, T. A., and P. R. Cook. 1996. Mimosine arrests the cell cycle after cells enter S-phase. Exp. Cell Res. 222:275-280.
    • (1996) Exp. Cell Res. , vol.222 , pp. 275-280
    • Hughes, T.A.1    Cook, P.R.2
  • 26
    • 0033430117 scopus 로고    scopus 로고
    • Cell adhesion: Old and new questions
    • Hynes, R. O. 1999. Cell adhesion: old and new questions. Trends Cell Biol. 9:M33-M37.
    • (1999) Trends Cell Biol. , vol.9
    • Hynes, R.O.1
  • 27
    • 0033566695 scopus 로고    scopus 로고
    • Cell cycle arrest and inhibition of anoikis by galectin-3 in human breast epithelial cells
    • Kim, H. R., H. M. Lin, H. Biliran, and A. Raz. 1999. Cell cycle arrest and inhibition of anoikis by galectin-3 in human breast epithelial cells. Cancer Res. 59:4148-4154.
    • (1999) Cancer Res. , vol.59 , pp. 4148-4154
    • Kim, H.R.1    Lin, H.M.2    Biliran, H.3    Raz, A.4
  • 28
    • 0029011805 scopus 로고
    • Cell cycle and apoptosis: Common pathways to life and death
    • King, K. L., and J. A. Cidlowski. 1995. Cell cycle and apoptosis: common pathways to life and death. J. Cell Biochem. 58:175-180.
    • (1995) J. Cell Biochem. , vol.58 , pp. 175-180
    • King, K.L.1    Cidlowski, J.A.2
  • 29
    • 0029033866 scopus 로고
    • Regulation of Bcl-2 expression by oncogenic Ras protein in hematopoietic cells
    • Kinoshita, T., T. Yokota, K. Arai, and A. Miyajima. 1995. Regulation of Bcl-2 expression by oncogenic Ras protein in hematopoietic cells. Oncogene 10:2207-2212.
    • (1995) Oncogene , vol.10 , pp. 2207-2212
    • Kinoshita, T.1    Yokota, T.2    Arai, K.3    Miyajima, A.4
  • 30
    • 0036282745 scopus 로고    scopus 로고
    • Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery
    • Konishi, Y., M. Lehtinen, N. Donovan, and A. Bonni. 2002. Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery. Mol. Cell 9:1005-1016.
    • (2002) Mol. Cell , vol.9 , pp. 1005-1016
    • Konishi, Y.1    Lehtinen, M.2    Donovan, N.3    Bonni, A.4
  • 31
    • 0033602015 scopus 로고    scopus 로고
    • Mimosine arrests proliferating human cells before onset of DNA replication in a dose-dependent manner
    • Krude, T. 1999. Mimosine arrests proliferating human cells before onset of DNA replication in a dose-dependent manner. Exp. Cell Res. 247:148-159.
    • (1999) Exp. Cell Res. , vol.247 , pp. 148-159
    • Krude, T.1
  • 32
    • 0025189329 scopus 로고
    • A reversible arrest point in the late G1 phase of the mammalian cell cycle
    • Lalande, M. 1990. A reversible arrest point in the late G1 phase of the mammalian cell cycle. Exp. Cell Res. 186:332-339.
    • (1990) Exp. Cell Res. , vol.186 , pp. 332-339
    • Lalande, M.1
  • 33
    • 0038482050 scopus 로고    scopus 로고
    • Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim
    • Ley, R., K. Balmanno, K. Hadfield, C. Weston, and S. J. Cook. 2003. Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim. J. Biol. Chem. 278:18811-18816.
    • (2003) J. Biol. Chem. , vol.278 , pp. 18811-18816
    • Ley, R.1    Balmanno, K.2    Hadfield, K.3    Weston, C.4    Cook, S.J.5
  • 34
    • 1542275411 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover
    • Ley, R., K. E. Ewings, K. Hadfield, E. Howes, K. Balmanno, and S. J. Cook. 2004. Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover. J. Biol. Chem. 279:8837-8847.
    • (2004) J. Biol. Chem. , vol.279 , pp. 8837-8847
    • Ley, R.1    Ewings, K.E.2    Hadfield, K.3    Howes, E.4    Balmanno, K.5    Cook, S.J.6
  • 35
    • 0242521470 scopus 로고    scopus 로고
    • Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function
    • Luciano, F., A. Jacquel, P. Colosetti, M. Herrant, S. Cagnol, G. Pages, and P. Auberger. 2003. Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function. Oncogene 22:6785-6793.
    • (2003) Oncogene , vol.22 , pp. 6785-6793
    • Luciano, F.1    Jacquel, A.2    Colosetti, P.3    Herrant, M.4    Cagnol, S.5    Pages, G.6    Auberger, P.7
  • 36
    • 1642343617 scopus 로고    scopus 로고
    • Role of Bim in the survival pathway induced by Raf in epithelial cells
    • Marani, M., D. Hancock, R. Lopes, T. Tenev, J. Downward, and N. R. Lemoine. 2004. Role of Bim in the survival pathway induced by Raf in epithelial cells. Oncogene 23:2431-2441.
    • (2004) Oncogene , vol.23 , pp. 2431-2441
    • Marani, M.1    Hancock, D.2    Lopes, R.3    Tenev, T.4    Downward, J.5    Lemoine, N.R.6
  • 37
  • 38
    • 0036222549 scopus 로고    scopus 로고
    • Sensing the environment: A historical perspective on integrin signal transduction
    • Miranti, C. K., and J. S. Brugge. 2002. Sensing the environment: a historical perspective on integrin signal transduction. Nat. Cell Biol. 4:E83-E90.
    • (2002) Nat. Cell Biol. , vol.4
    • Miranti, C.K.1    Brugge, J.S.2
  • 41
    • 0041621478 scopus 로고    scopus 로고
    • Chemical inhibitors of cyclin-dependent kinases control proliferation, apoptosis and differentiation of oligodendroglial cells
    • Nguyen, L., B. Malgrange, V. Rocher, G. Hans, G. Moonen, J. M. Rigo, and S. Belachew. 2003. Chemical inhibitors of cyclin-dependent kinases control proliferation, apoptosis and differentiation of oligodendroglial cells. Int. J. Dev. Neurosci. 21:321-326.
    • (2003) Int. J. Dev. Neurosci. , vol.21 , pp. 321-326
    • Nguyen, L.1    Malgrange, B.2    Rocher, V.3    Hans, G.4    Moonen, G.5    Rigo, J.M.6    Belachew, S.7
  • 43
    • 0029862497 scopus 로고    scopus 로고
    • A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes
    • Ory, D. S., B. A. Neugeboren, and R. C. Mulligan. 1996. A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes. Proc. Natl. Acad. Sci. USA 93:11400-11406.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11400-11406
    • Ory, D.S.1    Neugeboren, B.A.2    Mulligan, R.C.3
  • 45
    • 0042704792 scopus 로고    scopus 로고
    • Epidermal growth factor inhibition of c-Myc-mediated apoptosis through Akt and Erk involves Bcl-xL upregulation in mammary epithelial cells
    • Ramljak, D., C. M. Coticchia, T. G. Nishanian, M. Saji, M. D. Ringel, S. D. Conzen, and R. B. Dickson. 2003. Epidermal growth factor inhibition of c-Myc-mediated apoptosis through Akt and Erk involves Bcl-xL upregulation in mammary epithelial cells. Exp. Cell Res. 287:397-410.
    • (2003) Exp. Cell Res. , vol.287 , pp. 397-410
    • Ramljak, D.1    Coticchia, C.M.2    Nishanian, T.G.3    Saji, M.4    Ringel, M.D.5    Conzen, S.D.6    Dickson, R.B.7
  • 46
    • 0036134935 scopus 로고    scopus 로고
    • Germ line transmission of the Cdk4(R24C) mutation facilitates tumorigenesis and escape from cellular senescence
    • Rane, S. G., S. C. Cosenza, R. V. Mettus, and E. P. Reddy. 2002. Germ line transmission of the Cdk4(R24C) mutation facilitates tumorigenesis and escape from cellular senescence. Mol. Cell. Biol. 22:644-656.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 644-656
    • Rane, S.G.1    Cosenza, S.C.2    Mettus, R.V.3    Reddy, E.P.4
  • 48
    • 0032560514 scopus 로고    scopus 로고
    • Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: Involvement of MEK upstream of Bad phosphorylation
    • Scheid, M. P., and V. Duronio. 1998. Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation. Proc. Natl. Acad. Sci. USA 95:7439-7444.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 7439-7444
    • Scheid, M.P.1    Duronio, V.2
  • 49
    • 0032747134 scopus 로고    scopus 로고
    • Regulation of bad phosphorylation and association with Bcl-x(L) by the MAPK/Erk kinase
    • Scheid, M. P., K. M. Schubert, and V. Duronio. 1999. Regulation of bad phosphorylation and association with Bcl-x(L) by the MAPK/Erk kinase. J. Biol. Chem. 274:31108-31113.
    • (1999) J. Biol. Chem. , vol.274 , pp. 31108-31113
    • Scheid, M.P.1    Schubert, K.M.2    Duronio, V.3
  • 50
    • 0037037374 scopus 로고    scopus 로고
    • A novel form of constitutively active farnesylated Akt1 prevents mammary epithelial cells from anoikis and suppresses chemotherapy-induced apoptosis
    • Schmidt, M., S. Hovelmann, and T. L. Beckers. 2002. A novel form of constitutively active farnesylated Akt1 prevents mammary epithelial cells from anoikis and suppresses chemotherapy-induced apoptosis. Br. J. Cancer 87:924-932.
    • (2002) Br. J. Cancer , vol.87 , pp. 924-932
    • Schmidt, M.1    Hovelmann, S.2    Beckers, T.L.3
  • 51
    • 0035871383 scopus 로고    scopus 로고
    • Analysis of the transcriptional program induced by Raf in epithelial cells
    • Schulze, A., K. Lehmann, H. B. Jefferies, M. McMahon, and J. Downward. 2001. Analysis of the transcriptional program induced by Raf in epithelial cells. Genes Dev. 15:981-994.
    • (2001) Genes Dev. , vol.15 , pp. 981-994
    • Schulze, A.1    Lehmann, K.2    Jefferies, H.B.3    McMahon, M.4    Downward, J.5
  • 52
    • 0034902905 scopus 로고    scopus 로고
    • Integrins and cell proliferation: Regulation of cyclin-dependent kinases via cytoplasmic signaling pathways
    • Schwartz, M. A., and R. K. Assoian. 2001. Integrins and cell proliferation: regulation of cyclin-dependent kinases via cytoplasmic signaling pathways. J. Cell Sci. 114:2553-2560.
    • (2001) J. Cell Sci. , vol.114 , pp. 2553-2560
    • Schwartz, M.A.1    Assoian, R.K.2
  • 53
    • 0033919727 scopus 로고    scopus 로고
    • Apoptosis, anoikis and their relevance to the pathobiology of colon cancer
    • Shanmugathasan, M., and S. Jothy. 2000. Apoptosis, anoikis and their relevance to the pathobiology of colon cancer. Pathol. Int. 50:273-279.
    • (2000) Pathol. Int. , vol.50 , pp. 273-279
    • Shanmugathasan, M.1    Jothy, S.2
  • 54
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • Sherr, C. J., and J. M. Roberts. 1999. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 13:1501-1512.
    • (1999) Genes Dev. , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 58
    • 0033109535 scopus 로고    scopus 로고
    • Adhesion-mediated signaling in the regulation of mammary epithelial cell survival
    • Streuli, C. H., and A. P. Gilmore. 1999. Adhesion-mediated signaling in the regulation of mammary epithelial cell survival. J. Mammary Gland Biol. Neoplasia 4:183-191.
    • (1999) J. Mammary Gland Biol. Neoplasia , vol.4 , pp. 183-191
    • Streuli, C.H.1    Gilmore, A.P.2
  • 59
    • 0034682037 scopus 로고    scopus 로고
    • Cell-cycle inhibitors: Three families united by a common cause
    • Vidal, A., and A. Koff. 2000. Cell-cycle inhibitors: three families united by a common cause. Gene 247:1-15.
    • (2000) Gene , vol.247 , pp. 1-15
    • Vidal, A.1    Koff, A.2
  • 60
    • 0034627859 scopus 로고    scopus 로고
    • Mimosine arrests cells in G1 by enhancing the levels of p27(Kip1)
    • Wang, G., R. Miskimins, and W. K. Miskimins. 2000. Mimosine arrests cells in G1 by enhancing the levels of p27(Kip1). Exp. Cell Res. 254:64-71.
    • (2000) Exp. Cell Res. , vol.254 , pp. 64-71
    • Wang, G.1    Miskimins, R.2    Miskimins, W.K.3
  • 61
    • 4744348299 scopus 로고    scopus 로고
    • Bim is an apoptosis sensor that responds to loss of survival signals delivered by epidermal growth factor but not those provided by integrins
    • Wang, P., A. P. Gilmore, and C. H. Streuli. 2004. Bim is an apoptosis sensor that responds to loss of survival signals delivered by epidermal growth factor but not those provided by integrins. J. Biol. Chem. 279:41280-41285.
    • (2004) J. Biol. Chem. , vol.279 , pp. 41280-41285
    • Wang, P.1    Gilmore, A.P.2    Streuli, C.H.3
  • 62
    • 0025963379 scopus 로고
    • Mimosine reversibly arrests cell cycle progression at the G1-S phase border
    • Watson, P. A., H. H. Hanauske-Abel, A. Flint, and M. Lalande. 1991. Mimosine reversibly arrests cell cycle progression at the G1-S phase border. Cytometry 12:242-246.
    • (1991) Cytometry , vol.12 , pp. 242-246
    • Watson, P.A.1    Hanauske-Abel, H.H.2    Flint, A.3    Lalande, M.4
  • 63
    • 0037422172 scopus 로고    scopus 로고
    • Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways
    • Weston, C. R., K. Balmanno, C. Chalmers, K. Hadfield, S. A. Molton, R. Ley, E. F. Wagner, and S. J. Cook. 2003. Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways. Oncogene 22:1281-1293.
    • (2003) Oncogene , vol.22 , pp. 1281-1293
    • Weston, C.R.1    Balmanno, K.2    Chalmers, C.3    Hadfield, K.4    Molton, S.A.5    Ley, R.6    Wagner, E.F.7    Cook, S.J.8
  • 64
    • 0030955563 scopus 로고    scopus 로고
    • Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development
    • Yan, Y., J. Frisen, M. H. Lee, J. Massague, and M. Barbacid. 1997. Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development. Genes Dev. 11:973-983.
    • (1997) Genes Dev. , vol.11 , pp. 973-983
    • Yan, Y.1    Frisen, J.2    Lee, M.H.3    Massague, J.4    Barbacid, M.5
  • 65
    • 0032214980 scopus 로고    scopus 로고
    • Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase
    • Yu, D., T. Jing, B. Liu, J. Yao, M. Tan, T. J. McDonnell, and M. C. Hung. 1998. Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase. Mol. Cell 2:581-591.
    • (1998) Mol. Cell , vol.2 , pp. 581-591
    • Yu, D.1    Jing, T.2    Liu, B.3    Yao, J.4    Tan, M.5    McDonnell, T.J.6    Hung, M.C.7
  • 66
    • 0034745353 scopus 로고    scopus 로고
    • Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells
    • Zhou, B. P., Y. Liao, W. Xia, B. Spohn, M. H. Lee, and M. C. Hung. 2001. Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells. Nat. Cell Biol. 3:245-252.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 245-252
    • Zhou, B.P.1    Liao, Y.2    Xia, W.3    Spohn, B.4    Lee, M.H.5    Hung, M.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.