Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer

Oncogene

Volumn 19, Issue 19, 2000, Pages 2324-2330

  Zeng, Qiang Yuan ^a   Sun, Mei ^a   Feldman, Richard I ^b   Wang, Gen ^a   Ma, Xiao Ling ^a   Jiang, Chen ^a   Coppola, Domenico ^a   Nicosia, Santo V ^a   Cheng, Jin Q ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b BAYER AG   (Germany)

Author keywords

Akt; Ovarian cancer; PI 3 kinase; Signal transduction

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN ANTIBODY; PROTEIN KINASE B; PROTEIN KINASE B BETA; UNCLASSIFIED DRUG; WORTMANNIN;

APOPTOSIS; ARTICLE; CANCER STAGING; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; OVARY CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION;

EID: 0034604067     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1203598     Document Type: Article

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