Solution structure of the hydroperoxide of Co(III) phleomycin complexed with d(CCAGGCCTGG)2: Evidence for binding by partial intercalation

Nucleic Acids Research

Volumn 30, Issue 22, 2002, Pages 4881-4891

  Wu, W ^a   Vanderwall, Dana E ^c   Turner, Christopher J ^d   Hoehn, Silvia ^a   Chen, Jingyang ^a   Kozarich, John W ^c   Stubbe, JoAnne ^a,b  

^a Department of Chemistry ^*  (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN A2; BLEOMYCIN COBALT; BLEOMYCIN DERIVATIVE; BLEOMYCIN IRON; DOUBLE STRANDED DNA; HYDROPEROXIDE DERIVATIVE; PHLEOMYCIN;

BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DNA CLEAVAGE; DRUG DNA BINDING; DRUG STRUCTURE; INTERCALATION COMPLEX; MOLECULAR INTERACTION; MOLECULAR MECHANICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REVIEW; STRUCTURE ANALYSIS;

EID: 18744398387     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkf608     Document Type: Review

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