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Journal of the American Chemical Society

Volumn 123, Issue 36, 2001, Pages 8690-8700

Chemical and structural characterization of the interaction of bleomycin A2 with d(CGCGAATTCGCG)2. Efficient, double-strand DNA cleavage accessible without structural reorganization

(3) Keck, M V a,b Manderville, R A a,c Hecht, S M a

a UNIVERSITY OF VIRGINIA (United States)

b EMPORIA STATE UNIVERSITY (United States)

c WAKE FOREST UNIVERSITY (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLEAVAGE SITES;

DEBONDING; DRUG PRODUCTS; HYDROGEN; IRON; MOLECULAR ORIENTATION; NITROGEN COMPOUNDS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OLIGOMERS; SUBSTRATES; X RAY CRYSTALLOGRAPHY;

DNA;

ADENOSINE; BLEOMYCIN A2; CYTIDINE; OLIGONUCLEOTIDE;

ARTICLE; DNA CLEAVAGE; DNA DAMAGE; DRUG PROTEIN BINDING; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR OVERHAUSER EFFECT; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

BINDING SITES; BLEOMYCIN; DNA DAMAGE; IRON; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; OLIGONUCLEOTIDES; ZINC;

EID: 0035850519 PISSN: 00027863 EISSN: None Source Type: Journal
DOI: 10.1021/ja003795i Document Type: Article

Times cited : (27)

References (103)

1
- 0013945168
- (1966) J. Antibiot. , vol.19 A , pp. 200-209
- Umezawa, H.¹ Maeda, K.² Takeuchi, T.³ Okami, Y.⁴

2
- 0342572876
- Carter, S. K., Crooke, S. T., Umezawa, H., Eds.; Academic Press: New York
- (1978) Bleomycin: Current Status and New Developments , pp. 15-19
- Umezawa, H.¹

3
- 0003652651
- Academic Press: New York
- (1985) Bleomycin Chemotherapy
- Sikic, B.I.¹ Rozencweig, M.² Carter, S.K.³

4
- 33748719327
- (1987) Chem. Rev. , vol.87 , pp. 1107-1136
- Stubbe, J.¹ Kozarich, J.W.²

5
- 0000594666
- Neidle, S., Waring, M. J., Eds.; Macmillan Press: London
- (1993) Molecular Aspects of Anticancer Drug - DNA Interactions , pp. 197-242
- Natrajan, A.¹ Hecht, S.M.²

6
- 0028254320
- (1994) Prog. Nucleic Acid Res. Mol. Biol. , pp. 313-352
- Kane, S.A.¹ Hecht, S.M.²

7
- 11544259897
- (1998) Chem. Rev. , vol.98 , pp. 1153-1169
- Burger, R.M.¹

8
- 0000357885
- (1999) Chem. Rev. , vol.99 , pp. 2797-2816
- Claussen, C.A.¹ Long, E.D.²

9
- 0028535002
- (1994) Bioconj. Chem. , vol.5 , pp. 513-526
- Hecht, S.M.¹

10
- 0002713581
- Eggleston, D. S., Prescott, C. D., Pearson, N. D., Eds.; Academic Press: London
- (1998) The Many Faces of RNA , pp. 3-17
- Hecht, S.M.¹

11
- 0033980083
- (2000) J. Nat. Prod. , vol.63 , pp. 158-168
- Hecht, S.M.¹

12
- 0017094368
- (1976) Biochem. Biophys. Res. Commun. , vol.73 , pp. 814-822
- Sausville, E.A.¹ Peisach, J.² Horwitz, S.B.³

13
- 0018139256
- (1978) Biochemistry , vol.17 , pp. 2740-2745
- Sausville, E.A.¹ Peisach, J.² Horwitz, S.B.³

14
- 0018149642
- (1978) Biochemistry , vol.17 , pp. 2746-2754
- Sausville, E.A.¹ Stein, R.W.² Peisach, J.³ Horwitz, S.B.⁴

15
- 0019254695
- (1980) J. Biol. Chem. , vol.255 , pp. 11832-11838
- Burger, R.M.¹ Berkowitz, A.R.² Peisach, J.³ Horwitz, S.B.⁴

16
- 0019848907
- (1981) J. Biol. Chem. , vol.256 , pp. 8608-8615
- Giloni, L.¹ Takeshita, M.² Johnson, F.³ Iden, C.⁴ Grollman, A.P.⁵

17
- 0021759185
- (1984) Nucleic Acids Res. , vol.12 , pp. 1581-1592
- Uesugi, S.¹ Shida, T.² Ikehara, M.³ Kobayashi, Y.⁴ Kyogoku, Y.⁵

18
- 0022366988
- (1985) J. Nat. Prod. , vol.48 , pp. 869-877
- Sugiyama, H.¹ Ehrenfeld, G.M.² Shipley, J.B.³ Kilkuskie, R.E.⁴ Chang, L.-H.⁵ Hecht, S.M.⁶

19
- 0022377517
- (1985) Biochemistry , vol.24 , pp. 5735-5744
- Murugesan, N.¹ Xu, C.² Ehrenfeld, G.M.³ Sugiyama, H.⁴ Kilkuskie, R.E.⁵ Rodriguez, L.O.⁶ Chang, L.-H.⁷ Hecht, S.M.⁸

20
- 0020265892
- (1982) J. Biol. Chem. , vol.257 , pp. 8612-8614
- Burger, R.M.¹ Peisach, J.² Horwitz, S.B.³

21
- 0020587399
- (1983) J. Biol. Chem. , vol.258 , pp. 4694-4697
- Wu, J.C.¹ Kozarich, J.W.² Stubbe, J.³

22
- 0022296144
- (1985) Biochemistry , vol.24 , pp. 7562-7568
- Wu, J.C.¹ Kozarich, J.W.² Stubbe, J.³

23
- 0022336434
- (1985) Biochemistry , vol.24 , pp. 7569-7573
- Wu, J.W.¹ Kozarich, J.W.² Stubbe, J.³

24
- 0021927868
- (1985) J. Am. Chem. Soc. , vol.107 , pp. 4104-4105
- Sugiyama, H.¹ Xu, C.² Murugesan, N.³ Hecht, S.M.⁴

25
- 0022870733
- (1986) J. Am. Chem. Soc. , vol.108 , pp. 7130-7131
- Rabow, L.E.¹ Stubbe, J.² Kozarich, J.W.³ Gerlt, J.A.⁴

26
- 0023829779
- (1988) Biochemistry , vol.27 , pp. 58-67
- Sugiyama, H.¹ Xu, C.² Murugesan, N.³ Hecht, S.M.⁴ Van der Marel, G.A.⁵ Van Boom, J.H.⁶

27
- 0025035579
- (1990) J. Am. Chem. Soc. , vol.112 , pp. 3203-3208
- Rabow, L.¹ McGall, G.H.² Stubbe, J.³ Kozarich, J.W.⁴

28
- 0018146737
- (1978) Proc. Natl. Acad. Sci. U.S.A. , vol.75 , pp. 3608-3612
- D'Andrea, A.D.¹ Haseltine, W.A.²

29
- 0000936569
- (1978) Proc. Natl. Acad. Sci. U.S.A. , vol.75 , pp. 5983-5987
- Takeshita, M.¹ Grollman, A.P.² Ohtsubo, E.³ Ohtsubo, H.⁴

30
- 0014566576
- (1969) J. Antibiot. , vol.22 , pp. 446-448
- Suzuki, H.¹ Nagai, K.² Yamaki, H.³ Tanaka, N.⁴ Umezawa, H.⁵

31
- 0019949302
- (1982) Cancer Res , vol.42 , pp. 2779-2785
- Mirabelli, C.K.¹ Ting, A.² Huang, C.-H.³ Mong, S.⁴ Crooke, S.T.⁵

32
- 0024396338
- (1989) Biochemistry , vol.28 , pp. 5808-5814
- Povirk, L.F.¹ Han, Y.H.² Steighner, R.J.³

33
- 0025114681
- (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 8350-8354
- Steighner, R.J.¹ Povirk, L.F.²

34
- 0028925819
- (1995) Biochemistry , vol.34 , pp. 2065-2075
- Absalon, M.J.¹ Kozarich, J.W.² Stubbe, J.³

35
- 0028923387
- (1995) Biochemistry , vol.34 , pp. 2076-2086
- Absalon, M.J.¹ Wu, W.² Kozarich, J.W.³ Stubbe, J.⁴

36
- 0028126823
- (1994) J. Am. Chem. Soc. , vol.116 , pp. 10851-10852
- Manderville, R.A.¹ Ellena, J.A.² Hecht, S.M.³

37
- 0029099533
- (1995) J. Am. Chem. Soc. , vol.117 , pp. 7891-7903
- Manderville, R.A.¹ Ellena, J.A.² Hecht, S.M.³

38
- 0032237043
- (1998) Comments Inorg. Chem. , vol.20 , pp. 121-141
- Calafat, A.M.¹ Marzilli, L.G.²

39
- 0028171668
- (1994) J. Am. Chem. Soc. , vol.116 , pp. 10843-10844
- Wu, W.¹ Vanderwall, D.E.² Stubbe, J.³ Kozarich, J.W.⁴ Turner, C.J.⁵

40
- 0019843568
- (1981) J. Mol. Biol. , vol.151 , pp. 535-556
- Drew, H.R.¹ Dickerson, R.E.²

41
- 0020476728
- (1982) Science , vol.216 , pp. 581-590
- Patel, D.J.¹ Pardi, A.² Itakura, K.³

42
- 0020744256
- (1983) Proc. Natl. Acad. Sci. U.S.A. , vol.80 , pp. 2184-2188
- Patel, D.J.¹ Ikuta, S.² Kozlowski, S.³ Itakura, K.⁴

43
- 0021105577
- (1983) J. Mol. Biol. , vol.171 , pp. 319-336
- Hare, D.R.¹ Wemmer, D.E.² Chou, S.³ Drobny, G.J.⁴ Reid, B.R.⁵

44
- 0032387836
- (1998) Biochemistry , vol.37 , pp. 16877-16887
- Shui, X.¹ Sines, C.C.² McFail-Isom, L.³ Van Derveer, D.⁴ Williams, L.D.⁵

45
- 0033585580
- (1999) J. Am. Chem. Soc. , vol.121 , pp. 470-471
- Tereshko, V.¹ Minasov, G.² Egli, M.³

46
- 0020394591
- (1982) Proc. Natl. Acad. Sci. U.S.A. , vol.79 , pp. 6424-6428
- Patel, D.¹

47
- 0021959842
- (1985) Proc. Natl. Acad. Sci. U.S.A. , vol.82 , pp. 1376-1380
- Kopka, M.L.¹ Yoon, C.² Goodsell, D.³ Pjura, P.⁴ Dickerson, R.E.⁵

48
- 0024296533
- (1988) Nucleic Acids Res. , vol.16 , pp. 2671-2690
- Teng, M.¹ Usman, N.² Frederick, C.A.³ Wang, A.H.⁴

49
- 0024291323
- (1988) Biochemistry , vol.27 , pp. 8088-8096
- Pelton, J.G.¹ Wemmer, D.E.²

50
- 0025762608
- (1991) Biochemistry , vol.30 , pp. 1372-1385
- Lane, A.N.¹ Jenkins, T.C.² Brown, T.³ Neidle, S.⁴

51
- 0028956354
- (1995) Biochemistry , vol.34 , pp. 4983-4993
- Goodsell, D.S.¹ Kopka, M.L.² Dickerson, R.E.³

52
- 0025079009
- (1990) J. Am. Chem. Soc. , vol.112 , pp. 3196-3203
- Rabow, L.E.¹ Stubbe, J.² Kozarich, J.W.³

53
- 0027669345
- (1993) J. Biomol. NMR , vol.3 , pp. 577-595
- Kellogg, G.W.¹ Schweitzer, B.I.²

54
- 0018292827
- (1979) Biochemistry , vol.18 , pp. 3439-3445
- Oppenheimer, N.J.¹ Rodriguez, L.O.² Hecht, S.M.³

55
- 0023945323
- (1988) Eur. J. Biochem. , vol.173 , pp. 211-225
- Akkerman, M.A.J.¹ Haasnoot, G.A.G.² Hilbers, C.W.³

56
- 0002219497
- (1992) Adv. DNA Sequence Specific Agents , vol.1 , pp. 89
- Wilson, W.D.¹ Li, Y.² Veal, J.M.³

57
- 0019572105
- (1981) Proc. Natl. Acad. Sci. U.S.A. , vol.78 , pp. 2967-2971
- Glickson, J.D.¹ Pillai, R.P.² Sakai, T.T.³

58
- 0021739431
- (1984) J. Biomol. Struct. Dyn. , vol.2 , pp. 449
- Haasnoot, C.A.G.¹ Pandit, U.K.² Kruk, C.³ Hilbers, C.W.⁴

59
- 0021915285
- (1985) Biochemistry , vol.24 , pp. 81-92
- Ehrenfeld, G.M.¹ Rodriguez, L.O.² Hecht, S.M.³ Chang, C.⁴ Basus, V.J.⁵ Oppenheimer, N.⁶

60
- 0025052925
- (1990) J. Am. Chem. Soc. , vol.112 , pp. 7462-7474
- Akkerman, M.A.J.¹ Neijman, E.W.J.F.² Wijmenga, S.S.³ Hilbers, C.W.⁴ Bermel, W.⁵

61
- 20444483055
- (1980) Tetrahedron , vol.36 , pp. 2783-2792
- Haasnoot, C.A.G.¹ De Leeuw, F.A.A.M.² Altona, C.³

62
- 0026726087
- (1992) Methods Enzymol , vol.211 , pp. 286-306
- Van Wijk, J.¹ Huckriede, B.D.² Ippel, J.H.³ Altona, C.⁴

63
- 0001045906
- (1988) J. Magn. Reson. , vol.79 , pp. 429-438
- Bax, A.¹ Lerner, L.²

64
- 0024788819
- (1989) Biochemistry , vol.28 , pp. 10008-10021
- Nerdel, W.¹ Hare, D.R.² Reid, B.R.³

65
- 0028020868
- (1994) Biochemistry , vol.33 , pp. 11460-11475
- Schweitzer, B.I.¹ Mikita, T.² Kellogg, G.W.³ Gardner, K.H.⁴ Beardsley, G.P.⁵

66
- 0003919736
- Wiley: New York
- (1986) NMR of Proteins, Nucleic Acids
- Wuthrich, K.¹

67
- 0027957534
- (1994) Biochemistry , vol.33 , pp. 907-916
- Xu, R.X.¹ Nettesheim, D.² Otvos, J.D.³ Petering, D.H.⁴

68
- 0032878569
- (1999) J. Am. Chem. Soc. , vol.121 , pp. 9023-9033
- Aso, M.¹ Kondo, M.² Suemune, H.³ Hecht, S.M.⁴

69
- 0024507081
- (1989) J. Am. Chem. Soc. , vol.111 , pp. 2722-2724
- Van Atta, R.B.¹ Long, E.C.² Hecht, S.M.³ Van der Marel, G.A.⁴ Van Boom, J.H.⁵

70
- 0000597269
- (1998) Pure Appl. Chem. , vol.70 , pp. 307-311
- Quada J.C., Jr.¹ Zuber, G.F.² Hecht, S.M.³

71
- 0032538025
- (1998) J. Am. Chem. Soc. , vol.120 , pp. 9368-9369
- Zuber, G.¹ Quada J.C., Jr.² Hecht, S.M.³

72
- 0025082231
- (1990) Biochemistry , vol.29 , pp. 9225-9233
- Weidner, M.F.¹ Sigurdsson, S.T.² Hopkins, P.B.³

73
- 0026756615
- (1992) J. Am. Chem. Soc. , vol.114 , pp. 3144-3145
- Armstrong, R.W.¹ Salvati, M.E.² Nguyen, M.³

74
- 0027537909
- (1993) Biochemistry , vol.32 , pp. 2592-2600
- Lee, C.¹ Gibson, N.W.²

75
- 0026476007
- (1992) J. Biol. Chem. , vol.267 , pp. 24471-24475
- Hüttenhofer, A.¹ Hudson, S.² Noller, H.F.³ Mascharak, P.K.⁴

76
- 0028236912
- (1994) J. Inorg. Biochem. , vol.54 , pp. 199-206
- Muller, J.G.¹ Paikoff, S.J.² Rokita, S.E.³ Burrows, C.J.⁴

77
- 0033612736
- (1999) J. Am. Chem. Soc. , vol.121 , pp. 6956-6957
- Stemmler, A.J.¹ Burrows, C.J.²

78
- 0022483628
- (1986) J. Am. Chem. Soc. , vol.108 , pp. 3852-3854
- Sugiyama, H.¹ Kilkuskie, R.E.² Chang, L.-H.³ Ma, L.-T.⁴ Hecht, S.M.⁵ Van der Marel, G.A.⁶ Van Boom, J.H.⁷

79
- 0000551907
- Neidle, S., Waring, M., Eds.; MacMillan: London
- (1983) Molecular Aspects of Anti-cancer Drug Design , pp. 157-181
- Povirk, L.F.¹

80
- 0017548298
- (1977) Nucleic Acids Res. , vol.4 , pp. 3573-3580
- Povirk, L.F.¹ Wübker, W.² Köhnlein, W.³ Hutchinson, F.⁴

81
- 0023893971
- (1988) Biochemistry , vol.27 , pp. 3850-3857
- Povirk, L.F.¹ Houlgrave, C.W.²

82
- 0031148721
- (1997) Chem. Biol. , vol.4 , pp. 373-387
- Vanderwall, D.E.¹ Lui, S.M.² Wu, W.³ Turner, C.J.⁴ Kozarich, J.W.⁵ Stubbe, J.⁶

83
- 0003923459
- Abstracts, 311 -MEDI
- (1999) American Chemical Society Meeting
- Hoehn, S.¹ Junker, H.-D.² Kozarich, J.³ Turner, C.⁴ Stubbe, J.⁵

84
- 0035918531
- (2001) Biochemistry , vol.40 , pp. 5894-5905
- Hoehn, S.T.¹ Junker, H.-D.² Bunt, R.C.³ Turner, C.J.⁴ Stubbe, J.⁵

85
- 0022407545
- (1985) J. Am. Chem. Soc. , vol.107 , pp. 7765-7767
- Sugiyama, H.¹ Kilkuskie, R.E.² Hecht, S.M.³

86
- 0025148859
- (1990) J. Am. Chem. Soc. , vol.112 , pp. 5272-5276
- Long, E.C.¹ Hecht, S.M.² Van der Marel, G.A.³ Van Boom, J.H.⁴

87
- 0001611339
- (1979) Proc. Natl. Acad. Sci. U.S.A. , vol.76 , pp. 5616-5620
- Oppenheimer, N.J.¹ Rodriquez, L.O.² Hecht, S.M.³

88
- 33845556076
- (1981) J. Am. Chem. Soc. , vol.103 , pp. 3185-3191
- Matteucci, M.D.¹ Caruthers, M.H.²

89
- 0029623151
- (1995) Biochemistry , vol.34 , pp. 16715-16724
- Kane, S.A.¹ Hecht, S.M.² Sun, J.-S.³ Garestier, T.⁴ Hélène, C.⁵

90
- 0018961145
- (1980) Gene , vol.10 , pp. 177-183
- Tu, C.-P.D.¹ Cohen, S.N.²

91
- 0020714016
- (1983) Anal. Biochem. , vol.128 , pp. 281-286
- Banaszuk, A.M.¹ Deugau, K.V.² Sherwood, J.³ Michalak, M.⁴ Glick, B.R.⁵

92
- 0004136246
- Cold Spring Harbor Laboratory Press: New York
- (1989) Molecular Cloning, A Laboratory Approach; 2nd ed. , vol.2 , pp. 1311
- Sambrook, J.¹ Fritsch, E.F.² Maniatis, T.³

93
- 0026806738
- (1992) J. Am. Chem. Soc. , vol.114 , pp. 6278-6291
- Hamamichi, N.¹ Natrajan, A.² Hecht, S.M.³

94
- 33845555707
- (1982) J. Am. Chem. Soc. , vol.104 , pp. 7310-7311
- Plateau, P.¹ Guéron, M.²

95
- 0005963761
- (1982) J. Am. Chem. Soc. , vol.104 , pp. 6800-6801
- Piantini, U.¹ Sorensen, O.W.² Ernst, R.R.³

96
- 0026347331
- (1991) Biochemistry , vol.30 , pp. 10885-10895
- Blake, P.R.¹ Park, J.B.² Bryant, F.O.³ Aono, S.⁴ Magnuson, J.K.⁵ Eccleston, E.⁶ Howard, J.B.⁷ Summers, M.F.⁸ Adams, M.W.W.⁹

97
- 0000882469
- (1990) J. Magn. Reson. , vol.87 , pp. 375-384
- Baleja, J.D.¹ Moult, J.² Sykes, B.D.³

98
- 0026696172
- (1992) Biochemistry , vol.31 , pp. 3564-3574
- Kim, S.G.¹ Lin, L.² Reid, B.R.³

99
- 0024363370
- (1989) Biochemistry , vol.28 , pp. 5978-5984
- Gronenborn, A.M.¹ Clore, G.M.²

100
- 0025339406
- (1990) Biochemistry , vol.29 , pp. 4828-4839
- Baleja, J.D.¹ Pon, R.T.² Sykes, B.D.³

101
- 0026740675
- (1992) Biochemistry , vol.31 , pp. 6518-6532
- Huang, P.¹ Eisenberg, M.²

102
- 0024285896
- (1988) FEBS Lett. , vol.229 , pp. 317-324
- Nilges, M.¹ Clore, G.M.² Gronenborn, A.M.³

103
- 0020962967
- (1983) Biomol. Struct. Dyn. , vol.1 , pp. 231-252
- Tidor, B.¹ Irikura, K.K.² Brooks, B.R.³ Karplus, M.J.⁴

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