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(a) Pseudotetrapeptide A includes A, P, H, and V moieties of BLM in Figure 1; PMA is 2-[[N-(aminoethyl)amino]methyl]-4-[N-[2-(4-imidazolyl)ethyl]carbamoyl]-5- bromopyrimidine.
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(b) Although neither of these compounds possesses a carbamoyl ligand, these studies substantiate the feasibility of the primary amine as an axial ligand to the cobalt. In addition, to our knowledge, no crystallographic examples have been reported in which a carbamoyl group serves as an axial ligand to cobalt.
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58a With the binding mode shown in Figure 5, a single molecule of BLM could not catalyze this cleavage.
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