Transcriptional control of the core cell-death machinery

Trends in Biochemical Sciences

Volumn 29, Issue 4, 2004, Pages 193-199

  Kumar, Sharad ^a   Cakouros, Dimitrios ^a  

^a INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

HORMONE; TRANSCRIPTION FACTOR;

APOPTOSIS; CELL DAMAGE; CELL SURVIVAL; ENZYME ACTIVATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROCESSING; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; APOPTOSIS; CASPASES; CYTOKINES; DNA DAMAGE; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HORMONES; HUMANS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 1842813931     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibs.2004.02.001     Document Type: Review

References (74)

1. Baehrecke E.H. How death shapes life during development. Nat. Rev. Mol. Cell Biol. 3:2002;779-787.
2. Adams J.M. Ways of dying: multiple pathways to apoptosis. Genes Dev. 17:2003;2481-2495.
3. Hengartner M.O. The biochemistry of apoptosis. Nature. 407:2000;770-776.
4. Puthalakath H., Strasser A. Keeping killers on a tight leash: transcriptional and post translational control of the pro-apoptotic activity of BH3-only proteins. Cell Death Differ. 9:2002;505-512.
5. Adams J.M., Cory S. Life-or-death decisions by the Bcl-2 protein family. Trends Biochem. Sci. 26:2001;61-66.
6. Zou H., et al. Apaf-1, a human protein homologous to C. elegans CED-4 participates in cyt c dependent activation of caspase-3. Cell. 90:1997;405-413.
7. Aggarwal B.B. Signalling pathways of the TNF superfamily: a double-edged sword. Nat. Rev. Immunol. 3:2003;745-756.
8. Vaux D.L., Silke J. Mammalian mitochondrial IAP binding proteins. Biochem. Biophys. Res. Commun. 304:2003;499-504.
9. Dorstyn L., et al. The role of cytochrome c in caspase activation in Drosophila melanogaster cells. J. Cell Biol. 156:2002;1089-1098.
10. Marsden V.S., et al. Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome. Nature. 419:2002;634-637.
11. Shi Y. Mechanisms of caspase activation and inhibition during apoptosis. Mol. Cell. 9:2002;459-470.
12. Boatright K.M., et al. A unified model for apical caspase activation. Mol. Cell. 11:2003;529-541.
13. Fischer U., et al. Many cuts to ruin: a comprehensive update of caspase substrates. Cell Death Differ. 10:2003;76-100.
14. Metzstein M.M., Horvitz H.R. The C. elegans cell death specification gene ces-1 encodes a snail family zinc finger protein. Mol. Cell. 4:1999;309-319.
15. Thellmann M., et al. The Snail-like CES-1 protein of C.elegans can block the expression of the BH3-only cell death activator gene egl-1 by antagonizing the function of bHLH proteins. Development. 130:2003;4057-4071.
16. Cameron S., et al. PAG-3, a Zn-finger transcription factor, determines neuroblast fate in C. elegans. Development. 129:2002;1763-1774.
17. Grimes H.L., et al. The Gfi-1 protoncoprotein represses Bax expression and inhibits T-cell death. Proc. Natl. Acad. Sci. U. S. A. 93:1996;14569-14573.
18. Martin S.J. Destabilizing influences in apoptosis: sowing the seeds of IAP destruction. Cell. 109:2002;793-796.
19. Bergmann A., et al. The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling. Cell. 95:1998;331-341.
20. Kurada P., White K. Ras promotes cell survival in Drosophila by downregulating hid expression. Cell. 95:1998;319-329.
21. Mc Ginnis W., et al. Establishment and maintenance of position-specific expression of the Drosophila homeotic selector gene Deformed. Adv. Genet. 27:1990;363-402.
22. Lohmann I., et al. The Drosophila hox gene deformed sculpts head morphology via direct regulation of the apoptosis activator reaper. Cell. 110:2002;457-466.
23. Bello B.C., et al. A pulse of the Drosophila Hox protein Abdominal-A schedules the end of neural proliferation via neuroblast apoptosis. Neuron. 37:2003;209-219.
24. Hurle J.M., et al. Morphology and significance of programmed cell death in the developing limb bud of the vertebrate embryo. Microsc. Res. Tech. 34:1996;236-246.
25. Stadler H.S., et al. Loss of Eph-receptor expression correlates with loss of cell adhesion and chondrogenic capacity in Hoxa13 mutant limbs. Development. 128:2001;4177-4188.
26. Shimamoto T., et al. Inhibition of DLX-7 homeobox gene causes decreased expression of GATA-1 and c-myc genes and apoptosis. Proc. Natl. Acad. Sci. U. S. A. 94:1997;3245-3249.
27. Dodd M.H.I., Dodd J.M. The Biology of Metamorphosis. 1976;Academic Press. 467-599.
28. Tata J.R. Requirement for RNA and protein synthesis for induced regression of the tadpole tail in organ culture. Dev. Biol. 13:1966;77-94.
29. Shi, Y.B. (1999) Amphibian Metamorphosis: From Morphology to Molecular Biology, John Wiley & Sons, Inc.
30. Kucharova S., Farkas R. Hormone nuclear receptors and their ligands: role in programmed cell death. Endocr. Regul. 36:2002;37-60.
31. Distelhorst C.W. Recent insights into the mechanism of glucocorticosteroid-induced apoptosis. Cell Death Differ. 9:2002;6-19.
32. Jiang C., et al. Steroid regulated programmed cell death during Drosophila metamorphosis. Development. 124:1997;4673-4683.
33. Wang Z., et al. Microarray analysis uncovers the induction of the proapoptotic BH3-only protein Bim in multiple models of glucocorticoid-induced apoptosis. J. Biol. Chem. 278:2003;23861-23867.
34. Thummel C.S. Flies on steroids: Drosophila metamorphosis and the mechanisms of hormone action. Trends Genet. 12:1996;306-310.
35. Lee C.-Y., et al. E93 directs steroid-triggered programmed cell death in Drosophila. Mol. Cell. 6:2000;433-443.
36. Jiang C., et al. A steroid-triggered transcriptional hierarchy controls salivary gland cell death during Drosophila metamorphosis. Mol. Cell. 5:2000;445-455.
37. Cakouros D., et al. Ecdysone-induced expression of the caspase DRONC during hormone-dependent programmed cell death in Drosophila is regulated by Broad-Complex. J. Cell Biol. 157:2002;985-995.
38. Daish T., et al. Distinct promoter regions regulate spatial and temporal expression of the Drosophila caspase dronc. Cell Death Differ. 10:2003;1348-1356.
39. Bouillet P., et al. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis and to proclude autoimmunity. Science. 286:1999;1735-1738.
40. Strasser A., Bouillet P. The control of apoptosis in lymphocyte selection. Immunol. Rev. 193:2003;82-92.
41. Dijkers P.F., et al. Expression of the proapoptotic BCl-2 family member Bim is regulated by the forkhead transcription factor FKHRL1. Curr. Biol. 10:2000;1201-1204.
42. Stahl M., et al. The Forkhead transcription factor FOXO regulates transcription of p27kip1 and Bim in response to IL-2. J. Immunol. 168:2002;5024-5031.
43. Arai K., et al. Cytokines: coordinators of immune and inflammatory responses. Annu. Rev. Biochem. 59:1990;783-836.
44. Zhou P., et al. Mcl-1, a Bcl-2 family member delays the death of haemopoeitc cells under a variety of apoptosis-inducing conditions. Blood. 89:1997;630-643.
45. Wang J., et al. The Antiapoptotic gene mcl-1 is upregulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB. Mol. Cell. Biol. 19:1999;6195-6206.
46. Harris C.A., Johnson E.M. BH3-only BCl-2 family members are coordinately regulated by the JNK pathway and require Bax to induce apoptosis in neurons. J. Biol. Chem. 276:2001;37754-37760.
47. Whitfield J., et al. Dominant negative c-jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release. Neuron. 29:2001;629-643.
48. Gilley J., et al. FOXO transcription factors directly activate bim expression and promoter apoptosis in sympathetic neurons. J. Cell Biol. 162:2003;613-622.
49. Linseman D.A., et al. Insulin-like growth factor-I blocks Bcl-2 interacting mediator of cell death (Bim) induction and intrinsic death signaling in cerebellar granule neurons. J. Neurosci. 22:2002;9287-9297.
50. Rong P., et al. Nerve growth factor determines survival and death of PC12 cells by regulation of the bcl-x, bax and caspase-3 genes. J. Neurochem. 72:1999;2294-2300.
51. Evan G.I., Vousden K.H. Proliferation, cell cycle and apoptosis in cancer. Nature. 411:2001;342-348.
52. Sogame N., et al. Drosophila p53 preserves genomic stability by regulating cell death. Proc. Natl. Acad. Sci. U. S. A. 100:2003;4696-4701.
53. Zhou L., Steller H. Distinct pathways mediate UV-induced apoptosis in Drosophila embryos. Dev. Cell. 4:2003;599-605.
54. Moroni M.C., et al. Apaf-1 is a transcriptional target for E2F and p53. Nat. Cell Biol. 3:2001;552-558.
55. Fortin A., et al. APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death. J. Cell Biol. 155:2001;207-216.
56. Irwin M., et al. Role for the p53 homologue p73 in E2F-1-induced apoptosis. Nature. 407:2000;645-648.
57. Harbour J.W., Dean D.C. Rb function in cell cycle regulation and apoptosis. Nat. Cell Biol. 2:2000;E65-E67.
58. Nahle Z., et al. Direct coupling of the cell cycle and cell death machinery by E2F. Nat. Cell Biol. 4:2002;859-864.
59. Croxton R., et al. Direct repression of the Mcl-1 promoter by E2F1. Oncogene. 21:2002;1359-1369.
60. Martel C., et al. Inactivation of retinoblastoma family proteins by SV40 T antigen results in creation of a hepatocyte growth factor/scatter factor autocrine loop associated with an epithelial-fibroblastoid conversion and invasiveness. Cell Growth Differ. 8:1997;165-178.
61. Decary S., et al. The retinoblastoma protein binds the promoter of the survival gene bcl-2 and regulates its transcription in epithelial cells through transcription factor AP-2. Mol. Cell. Biol. 22:2002;7877-7888.
62. Oda E., et al. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science. 288:2000;1053-1058.
63. Nakano K., Vousden K.H. PUMA, a novel proapoptotic gene, is induced by p53. Mol. Cell. 7:2001;683-694.
64. Villunger A., et al. p53 and drug-induced apoptotic responses mediated by BH3-only proteins Puma and Noxa. Science. 302:2003;1036-1038.
65. Jeffers J.R., et al. Puma is an essential mediator of p53-dependent and -independent apoptotic pathways. Cancer Cell. 4:2003;321-328.
66. Shibue T., et al. Integral role of Noxa in p53-mediated apoptotic response. Genes Dev. 17:2003;2233-2238.
67. Han J., et al. Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals. Proc. Natl. Acad. Sci. U. S. A. 98:2001;11318-11323.
68. Li-Weber M., Krammer P.H. Function and regulation of the CD95 (APO-1/Fas) ligand in the immune system. Semin. Immunol. 15:2003;145-157.
69. Lakhani S., Flavell R.A. Caspases and T lymphocytes: a flip of the coin? Immunol. Rev. 193:2003;22-30.
70. Skurk C., et al. The Akt-regulated forkhead transcription factor FOXO3a controls endothelial cell viability through modulation of the caspase-8 inhibitor FLIP. J. Biol. Chem. 279:2003;1513-1525.
71. Gerondakis S., Strasser A. The role of Rel/NF-kappaB transcription factors in B lymphocyte survival. Semin. Immunol. 15:2003;159-166.
72. Wang C.Y., et al. NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis. Mol. Cell. Biol. 19:1999;5923-5929.
73. Liedtke C., et al. The human caspase-8 promoter sustains basal activity through SP1 and ETS-like transcription factors and can be up-regulated by a p53-dependent mechanism. J. Biol. Chem. 278:2003;27593-27604.
74. Moreno E., et al. Evolution of TNF signaling mechanisms: JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily. Curr. Biol. 12:2002;1263-1268.