PAG-3, a Zn-finger transcription factor, determines neuroblast fate in C. elegans

Development

Volumn 129, Issue 7, 2002, Pages 1763-1774

  Cameron, Scott ^a   Clark, Scott G ^a   McDermott, Joan B ^a   Aamodt, Eric ^a   Horvitz, H Robert ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

C. elegans; Cell lineage; Neuroblast fate; Programmed cell death

Indexed keywords

MUTANT PROTEIN; PROTEIN PAG3; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ANIMAL CELL; APOPTOSIS; CAENORHABDITIS ELEGANS; CELL DIVISION; CELL FATE; CELL LINEAGE; CONTROLLED STUDY; DROSOPHILA; GENE MUTATION; MALE; NERVE CELL DIFFERENTIATION; NEUROBLAST; NONHUMAN; PARASITE DEVELOPMENT; PHENOTYPE; PRIORITY JOURNAL; REVIEW; STEM CELL; VENTRAL ROOT;

ANIMALS; APOPTOSIS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL DIFFERENTIATION; CELL DIVISION; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, HELMINTH; GENES, HOMEOBOX; INTERNEURONS; MOTOR NEURONS; MUTATION; NERVOUS SYSTEM; NEURONS; NUCLEAR PROTEINS; SPECIES SPECIFICITY; STEM CELLS; TRANSCRIPTION FACTORS; ZINC FINGERS;

ANIMALIA; CAENORHABDITIS; CAENORHABDITIS ELEGANS; INVERTEBRATA; MAMMALIA; STAPHYLOCOCCUS PHAGE 3A;

EID: 0036336510     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (64)

1. The genetics of Caenorhabditis elegans
2. Anterior organization of the Caenorhabditis elegans embryo by the labial-like Hox gene ceh-13
3. The Caenorhabditis elegans homeobox gene cluster
4. Mutations that lead to reiterations in the cell lineages of C. elegans
5. The neural circuit for touch sensitivity in Caenorhabditis elegans
6. Control of cell fate in the tail region of C. elegans by the gene egl-5
7. Control of cell fates in the central body region of C. elegans by the homeobox gene lin-39
8. Regulation of touch receptor differentiation by the Caenorhabditis elegans mec-3 and unc-86 genes
9. Two C. elegans genes control the programmed deaths of specific cells in the pharynx
10. Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans
11. A genetic pathway for the specification of the vulval cell lineages of Caenorhabditis elegans
12. The unc-86 gene product couples cell lineage and cell identity in C. elegans
13. The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors
14. Molecular analysis of the C. elegans cell lineage gene lin-11
15. Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-11
16. Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein
17. The Gfi-1 protooncoprotein represses Bax expression and inhibits T-cell death
18. C. elegans Slit acts in midline, dorsal-ventral, and anterior-posterior guidance via the SAX-3/Robo receptor
19. Mutations affecting programmed cell deaths in the nematode Caenorhabditis elegans
20. Genetic control of programmed cell death in the nematode Caenorhabditis elegans
21. Reversal of apoptosis by the leukaemia-associated E2A-HLF chimaeric transcription factor
22. SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein
23. pag-3, a Caenorhabditis elegans gene involved in touch neuron gene expression and coordinated movement
24. The C. elegans gene pag-3 is homologous to the zinc finger proto-oncogene gfi-1
25. A gene involved in the development of the posterior body region of C. elegans
26. Growth cones stall and collapse during axon outgrowth in Caenorhabditis elegans
27. EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins
28. Organogenesis in C. elegans: Positioning of neurons and muscles in the egg-laying system
29. The GABAergic nervous system of Caenorhabditis elegans
30. Lethals, steriles and deficiencies in a region of the X chromosome of Caenorhabditis elegans
31. The C. elegans cell death specification gene ces-1 encodes a snail family zinc finger protein
32. Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2
33. Genetics of programmed cell death in C. elegans: Past, present and future
34. Expression of the unc-4 homeoprotein in Caenorhabditis elegans motor neurons specifies presynaptic input
35. C. elegans unc-4 gene encodes a homeodomain protein that determines the pattern of synaptic input to specific motor neurons
36. The lin11 LIM domain transcription factor is necessary for morphogenesis of C. elegans uterine cells
37. Senseless, a Zn finger transcription factor, is necessary and sufficient for sensory organ development in Drosophila
38. Caenorhabditis elegans rab-3 mutant synapses exhibit impaired function and are partially depleted of vesicles
39. The Groucho-like transcription factor UNC-37 functions with the neural specificity gene unc-4 to govern motor neuron identity in C. elegans
40. Mouse models of cell death
41. Phagocytosis promotes programmed cell death in C. elegans
42. C. elegans II
43. Multiple HOM-C gene interactions specify cell fates in the nematode central nervous system
44. P-element insertion alleles of essential genes on the third chromosome of Drosophila melanogaster: Mutations affecting embryonic PNS development
45. Characterization of pal-1, a common proviral insertion site in murine leukemia virus-induced lymphomas of c-myc and Pim-1 transgenic mice
46. Localization of FMRFamide-like peptides in Caenorhabditis elegans
47. Evidence implicating Gfi-1 and Pim-1 in pre-T-cell differentiation steps associated with beta-selection
48. Programmed cell death in Drosophila
49. The genetic control of cell lineage during nematode development
50. Post-embryonic development in the ventral cord of Caenorhabditis elegans
51. Post-embryonic cell lineages of the nematode, Caenorhabditis elegans
52. The embryonic cell lineage of the nematode Caenorhabditis elegans
53. VP16-activation of the C. elegans neural specification transcription factor UNC-86 suppresses mutations in downstream genes and causes defects in neural migration and axon outgrowth
54. The Gfi-1B proto-oncoprotein represses p21WAF1 and inhibits myeloid cell differentiation
55. Divergent seven transmembrane receptors are candidate chemosensory receptors in C. elegans
56. Identification of cooperating oncogenes in E μ-myc transgenic mice by provirus tagging
57. Mutations in the Caenorhabditis elegans unc-4 gene alter the synaptic input to ventral cord motor neurons
58. The structure of the ventral nerve cord of Caenorhabditis elegans
59. The structure of the nervous system of the nematode Caenorhabditis elegans
60. UNC-4/UNC-37-dependent repression of motor neuron-specific genes controls synaptic choice in Caenorhabditis elegans
61. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme
62. CED-1 is a transmembrane receptor that mediates corpse engulfment in C. elegans
63. Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor