-
1
-
-
0038724819
-
Deregulation of NF-kappaB and its upstream kinases in cancer
-
Sun SC, Xiao G. Deregulation of NF-kappaB and its upstream kinases in cancer. Cancer Metastasis Rev. 2003;22: 405-422.
-
(2003)
Cancer Metastasis Rev
, vol.22
, pp. 405-422
-
-
Sun, S.C.1
Xiao, G.2
-
2
-
-
0037496130
-
Transducing signals from antigen receptors to nuclear factor kappaB
-
Ruland J, Mak TW. Transducing signals from antigen receptors to nuclear factor kappaB. Immunol Rev. 2003;193:93-100.
-
(2003)
Immunol Rev
, vol.193
, pp. 93-100
-
-
Ruland, J.1
Mak, T.W.2
-
4
-
-
0034005455
-
CD40 ligand in CLL pathogenesis and therapy
-
Schatmer EJ. CD40 ligand in CLL pathogenesis and therapy. Leuk Lymphoma. 2000;37:461-472.
-
(2000)
Leuk Lymphoma
, vol.37
, pp. 461-472
-
-
Schatmer, E.J.1
-
5
-
-
0037328613
-
NF-kappaB activation in cancer: A challenge for ubiquitination- and proteasome-based therapeutic approach
-
Amit S, Ben-Neriah Y. NF-kappaB activation in cancer: a challenge for ubiquitination- and proteasome-based therapeutic approach. Semin Cancer Biol. 2003;13:15-28.
-
(2003)
Semin Cancer Biol
, vol.13
, pp. 15-28
-
-
Amit, S.1
Ben-Neriah, Y.2
-
6
-
-
0028174061
-
Function and activation of NF-kappa B in the immune system
-
Baeuerle PA, Henkel T. Function and activation of NF-kappa B in the immune system. Annu Rev Immunol. 1994;12:141-179.
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 141-179
-
-
Baeuerle, P.A.1
Henkel, T.2
-
7
-
-
0034668149
-
Nuclear factor-kappa B, cancer, and apoptosis
-
Bours V, Bentires-Alj M, Hellin AC, et al. Nuclear factor-kappa B, cancer, and apoptosis. Biochem Pharmacol. 2000; 60:1085-1089.
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 1085-1089
-
-
Bours, V.1
Bentires-Alj, M.2
Hellin, A.C.3
-
8
-
-
0037096221
-
Nf-kappa B: Arresting a major culprit in cancer
-
Haefner B. NF-kappa B: arresting a major culprit in cancer. Drug Discov Today. 2002;7:653-663.
-
(2002)
Drug Discov Today
, vol.7
, pp. 653-663
-
-
Haefner, B.1
-
9
-
-
0022481133
-
Multiple nuclear factors interact with the immunoglobulin enhancer sequences
-
Sen R, Baltimore D. Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell. 1986;46:705-716.
-
(1986)
Cell
, vol.46
, pp. 705-716
-
-
Sen, R.1
Baltimore, D.2
-
11
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-[kappa]B activity
-
Karin M, Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu Rev Immunol. 2000;18:621-663.
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
12
-
-
0035266072
-
ATP-dependent proteases degrade their substrates by processively unraveling them from the degradation signal
-
Lee C, Schwartz MP, Prakash S, Iwakura M, Matouschek A. ATP-dependent proteases degrade their substrates by processively unraveling them from the degradation signal. Mol Cell. 2001;7:627-637.
-
(2001)
Mol Cell
, vol.7
, pp. 627-637
-
-
Lee, C.1
Schwartz, M.P.2
Prakash, S.3
Iwakura, M.4
Matouschek, A.5
-
13
-
-
0029924035
-
A glycine-rich region in NF-kappaB p105 functions as a processing signal for the generation of the p50 subunit
-
Lin L, Ghosh S. A glycine-rich region in NF-kappaB p105 functions as a processing signal for the generation of the p50 subunit. Mol Cell Biol. 1996;16:2248-2254.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 2248-2254
-
-
Lin, L.1
Ghosh, S.2
-
14
-
-
0032954038
-
Structural motifs involved in ubiquitin-mediated processing of the NF-kappaB precursor p105: Roles of the glycine-rich region and a downstream ubiquitination domain
-
Orian A, Schwartz AL, Israel A, Whiteside S, Kahana C, Ciechanover A. Structural motifs involved in ubiquitin-mediated processing of the NF-kappaB precursor p105: roles of the glycine-rich region and a downstream ubiquitination domain. Mol Cell Biol. 1999;19:3664-3673.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 3664-3673
-
-
Orian, A.1
Schwartz, A.L.2
Israel, A.3
Whiteside, S.4
Kahana, C.5
Ciechanover, A.6
-
15
-
-
0030271387
-
Nf-kappa B: Ten years after
-
Baeuerle PA, Baltimore D. NF-kappa B: ten years after. Cell. 1996;87:13-20.
-
(1996)
Cell
, vol.87
, pp. 13-20
-
-
Baeuerle, P.A.1
Baltimore, D.2
-
16
-
-
0033596124
-
Aberrant rel/nfkb genes and activity in human cancer
-
Rayet B, Gelinas C. Aberrant rel/nfkb genes and activity in human cancer. Oncogene. 1999;18:6938-6947.
-
(1999)
Oncogene
, vol.18
, pp. 6938-6947
-
-
Rayet, B.1
Gelinas, C.2
-
17
-
-
0028181539
-
Function of NF-kappa B/Rel binding sites in the major histocompatibility complex Class II invariant chain promoter is dependent on cell-specific binding of different NF-kappa B/Rel subunits
-
Brown AM, Linhoff MW, Stein B, et al. Function of NF-kappa B/Rel binding sites in the major histocompatibility complex Class II invariant chain promoter is dependent on cell-specific binding of different NF-kappa B/Rel subunits. Mol Cell Biol. 1994;14:2926-2935.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 2926-2935
-
-
Brown, A.M.1
Linhoff, M.W.2
Stein, B.3
-
18
-
-
0028178430
-
Purification, reconstitution, and I kappa B association of the c-Rel-p65 (RelA) complex, a strong activator of transcription
-
Hansen SK, Baeuerle PA, Blasi F. Purification, reconstitution, and I kappa B association of the c-Rel-p65 (RelA) complex, a strong activator of transcription. Mol Cell Biol. 1994;14:2593-2603.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 2593-2603
-
-
Hansen, S.K.1
Baeuerle, P.A.2
Blasi, F.3
-
19
-
-
0028141640
-
Differential DNA sequence specificity and regulation of HIV-1 enhancer activity by cRel-RelA transcription factor
-
Hansen SK, Guerrini L, Blasi F. Differential DNA sequence specificity and regulation of HIV-1 enhancer activity by cRel-RelA transcription factor. J Biol Chem. 1994;269:22230-22237.
-
(1994)
J Biol Chem
, vol.269
, pp. 22230-22237
-
-
Hansen, S.K.1
Guerrini, L.2
Blasi, F.3
-
20
-
-
0026764920
-
NF-kappa B subunit regulation in nontransformed CD4+ T lymphocytes
-
Kang SM, Tran AC, Grilli M, Lenardo MJ. NF-kappa B subunit regulation in nontransformed CD4+ T lymphocytes. Science. 1992;256:1452-1456.
-
(1992)
Science
, vol.256
, pp. 1452-1456
-
-
Kang, S.M.1
Tran, A.C.2
Grilli, M.3
Lenardo, M.J.4
-
21
-
-
0027190466
-
KBF1 (p50 NF-kappa B homodimer) acts as a repressor of H-2Kb gene expression in metastatic tumor cells
-
Plaksin D, Baeuerle PA, Eisenbach L. KBF1 (p50 NF-kappa B homodimer) acts as a repressor of H-2Kb gene expression in metastatic tumor cells. J Exp Med. 1993;177:1651-1662.
-
(1993)
J Exp Med
, vol.177
, pp. 1651-1662
-
-
Plaksin, D.1
Baeuerle, P.A.2
Eisenbach, L.3
-
22
-
-
0031897632
-
NF-kappa B and Rel proteins: Evolutionarily conserved mediators of immune responses
-
Ghosh S, May MJ, Kopp EB. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol. 1998;16:225-260.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 225-260
-
-
Ghosh, S.1
May, M.J.2
Kopp, E.B.3
-
23
-
-
0038605236
-
NF-kappaB and virus infection: Who controls whom?
-
Santoro MG, Rossi A, Amici C. NF-kappaB and virus infection: who controls whom? EMBO J. 2003;22:2552-2560.
-
(2003)
EMBO J
, vol.22
, pp. 2552-2560
-
-
Santoro, M.G.1
Rossi, A.2
Amici, C.3
-
24
-
-
0031586174
-
Identification and characterization of an IkappaB kinase
-
Regnier CH, Song HY, Gao X, Goeddel DV, Cao Z, Rothe M. Identification and characterization of an IkappaB kinase. Cell. 1997;90:373-383.
-
(1997)
Cell
, vol.90
, pp. 373-383
-
-
Regnier, C.H.1
Song, H.Y.2
Gao, X.3
Goeddel, D.V.4
Cao, Z.5
Rothe, M.6
-
25
-
-
0032541657
-
IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex
-
Rothwarf DM, Zandi E, Natoli G, Karin M. IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex. Nature. 1998;395:297-300.
-
(1998)
Nature
, vol.395
, pp. 297-300
-
-
Rothwarf, D.M.1
Zandi, E.2
Natoli, G.3
Karin, M.4
-
26
-
-
0032541670
-
IKAP is a scaffold protein of the IkappaB kinase complex
-
Cohen L, Henzel WJ, Baeuerle PA. IKAP is a scaffold protein of the IkappaB kinase complex. Nature. 1998;395:292-296.
-
(1998)
Nature
, vol.395
, pp. 292-296
-
-
Cohen, L.1
Henzel, W.J.2
Baeuerle, P.A.3
-
27
-
-
0030613551
-
The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation
-
Zandi E, Rothwarf DM, Delhase M, Hayakawa M, Karin M. The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation. Cell. 1997;91:243-252.
-
(1997)
Cell
, vol.91
, pp. 243-252
-
-
Zandi, E.1
Rothwarf, D.M.2
Delhase, M.3
Hayakawa, M.4
Karin, M.5
-
28
-
-
0032575379
-
Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: Discrimination between free and NF-kappaB-bound substrate
-
Zandi E, Chen Y, Karin M. Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate. Science. 1998;281:1360-1363.
-
(1998)
Science
, vol.281
, pp. 1360-1363
-
-
Zandi, E.1
Chen, Y.2
Karin, M.3
-
29
-
-
0032568792
-
Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation
-
Yamaoka S, Courtois G, Bessia C, et al. Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation. Cell. 1998;93:1231-1240.
-
(1998)
Cell
, vol.93
, pp. 1231-1240
-
-
Yamaoka, S.1
Courtois, G.2
Bessia, C.3
-
30
-
-
0033537719
-
Positive and negative regulation of IkappaB kinase activity through IKK-beta subunit phosphorylation
-
Delhase M, Hayakawa M, Chen Y, Karin M. Positive and negative regulation of IkappaB kinase activity through IKK-beta subunit phosphorylation. Science. 1999;284:309-313.
-
(1999)
Science
, vol.284
, pp. 309-313
-
-
Delhase, M.1
Hayakawa, M.2
Chen, Y.3
Karin, M.4
-
31
-
-
0030615201
-
Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases
-
Barnes PJ, Karin M. Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med. 1997;336:1066-1071.
-
(1997)
N Engl J Med
, vol.336
, pp. 1066-1071
-
-
Barnes, P.J.1
Karin, M.2
-
32
-
-
0033611588
-
Molecular mechanisms of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells
-
Krappmann D, Emmerich F, Kordes U, Scharschmidt E, Dorken B, Scheidereit C. Molecular mechanisms of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells. Oncogene. 1999;18:943-953.
-
(1999)
Oncogene
, vol.18
, pp. 943-953
-
-
Krappmann, D.1
Emmerich, F.2
Kordes, U.3
Scharschmidt, E.4
Dorken, B.5
Scheidereit, C.6
-
33
-
-
18844465632
-
Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells
-
Bargou RC, Emmerich F, Krappmann D, et al. Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells. J Clin Invest. 1997;100:2961-2969.
-
(1997)
J Clin Invest
, vol.100
, pp. 2961-2969
-
-
Bargou, R.C.1
Emmerich, F.2
Krappmann, D.3
-
34
-
-
0037043125
-
Rel/NF-kappa B/I kappa B signal transduction in the generation and treatment of human cancer
-
Gilmore T, Gapuzan ME, Kalaitzidis D, Starczynowski D. Rel/NF-kappa B/I kappa B signal transduction in the generation and treatment of human cancer. Cancer Lett. 2002; 181:1-9.
-
(2002)
Cancer Lett
, vol.181
, pp. 1-9
-
-
Gilmore, T.1
Gapuzan, M.E.2
Kalaitzidis, D.3
Starczynowski, D.4
-
35
-
-
0035137882
-
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB
-
Baldwin AS. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. J Clin Invest. 2001;107:241-246.
-
(2001)
J Clin Invest
, vol.107
, pp. 241-246
-
-
Baldwin, A.S.1
-
36
-
-
0035883151
-
NF-kappaB signaling pathways in mammalian and insect innate immunity
-
Silverman N, Maniatis T. NF-kappaB signaling pathways in mammalian and insect innate immunity. Genes Dev. 2001; 15:2321-2342.
-
(2001)
Genes Dev
, vol.15
, pp. 2321-2342
-
-
Silverman, N.1
Maniatis, T.2
-
37
-
-
0034175930
-
The IKK complex: An integrator of all signals that activate NF-kappaB?
-
Israel A. The IKK complex: an integrator of all signals that activate NF-kappaB? Trends Cell Biol. 2000;10:129-133.
-
(2000)
Trends Cell Biol
, vol.10
, pp. 129-133
-
-
Israel, A.1
-
38
-
-
0036724051
-
The carboxyl-terminal region of IkappaB kinase gamma (IKKgamma) is required for full IKK activation
-
Makris C, Roberts JL, Karin M. The carboxyl-terminal region of IkappaB kinase gamma (IKKgamma) is required for full IKK activation. Mol Cell Biol. 2002;22:6573-6581.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 6573-6581
-
-
Makris, C.1
Roberts, J.L.2
Karin, M.3
-
39
-
-
0034864799
-
Proteasome inhibitors: From research tools to drug candidates
-
Kisselev AF, Goldberg AL. Proteasome inhibitors: from research tools to drug candidates. Chem Biol. 2001;8:739-758.
-
(2001)
Chem Biol
, vol.8
, pp. 739-758
-
-
Kisselev, A.F.1
Goldberg, A.L.2
-
40
-
-
0033621956
-
The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L)
-
Chen C, Edelstein LC, Gelinas C. The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L). Mol Cell Biol. 2000;20:2687-2695.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 2687-2695
-
-
Chen, C.1
Edelstein, L.C.2
Gelinas, C.3
-
41
-
-
0032588317
-
NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis
-
Wang CY, Guttridge DC, Mayo MW, Baldwin AS Jr. NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis. Mol Cell Biol. 1999;19:5923-5929.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 5923-5929
-
-
Wang, C.Y.1
Guttridge, D.C.2
Mayo, M.W.3
Baldwin Jr., A.S.4
-
42
-
-
0032508414
-
NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
-
Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS Jr. NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science. 1998;281:1680-1683.
-
(1998)
Science
, vol.281
, pp. 1680-1683
-
-
Wang, C.Y.1
Mayo, M.W.2
Korneluk, R.G.3
Goeddel, D.V.4
Baldwin Jr., A.S.5
-
43
-
-
0037442674
-
VEGF expression in human macrophages is NF-kappaB-dependent: Studies using adenoviruses expressing the endogenous NF-kappaB inhibitor IkappaBalpha and a kinase-defective form of the IkappaB kinase 2
-
Kiriakidis S, Andreakos E, Monaco C, Foxwell B, Feldmann M, Paleolog E. VEGF expression in human macrophages is NF-kappaB-dependent: studies using adenoviruses expressing the endogenous NF-kappaB inhibitor IkappaBalpha and a kinase-defective form of the IkappaB kinase 2. J Cell Sci. 2003;116:665-674.
-
(2003)
J Cell Sci
, vol.116
, pp. 665-674
-
-
Kiriakidis, S.1
Andreakos, E.2
Monaco, C.3
Foxwell, B.4
Feldmann, M.5
Paleolog, E.6
-
44
-
-
0032039076
-
Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300
-
Zhong H, Voll RE, Ghosh S. Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. Mol Cell. 1998;1:661-671.
-
(1998)
Mol Cell
, vol.1
, pp. 661-671
-
-
Zhong, H.1
Voll, R.E.2
Ghosh, S.3
-
45
-
-
0034612636
-
Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation
-
Hoeflich KP, Luo J, Rubie EA, Tsao MS, Jin O, Woodgett JR. Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation. Nature. 2000;406:86-90.
-
(2000)
Nature
, vol.406
, pp. 86-90
-
-
Hoeflich, K.P.1
Luo, J.2
Rubie, E.A.3
Tsao, M.S.4
Jin, O.5
Woodgett, J.R.6
-
46
-
-
0035979737
-
Duration of nuclear NF-kappaB action regulated by reversible acetylation
-
Chen L, Fischle W, Verdin E, Greene WC. Duration of nuclear NF-kappaB action regulated by reversible acetylation. Science. 2001;293:1653-1657
-
(2001)
Science
, vol.293
, pp. 1653-1657
-
-
Chen, L.1
Fischle, W.2
Verdin, E.3
Greene, W.C.4
-
47
-
-
0025941525
-
Induction of NF-kappa B DNA-binding activity during the G0-to-G1 transition in mouse fibroblasts
-
Baldwin AS Jr., Azizkhan JC, Jensen DE, Beg AA, Coodly LR. Induction of NF-kappa B DNA-binding activity during the G0-to-G1 transition in mouse fibroblasts. Mol Cell Biol. 1991;11:4943-4951.
-
(1991)
Mol Cell Biol
, vol.11
, pp. 4943-4951
-
-
Baldwin Jr., A.S.1
Azizkhan, J.C.2
Jensen, D.E.3
Beg, A.A.4
Coodly, L.R.5
-
48
-
-
0030614504
-
Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator
-
Perkins ND, Felzien LK, Betts JC, Leung K, Beach DH, Nabel GJ. Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator. Science. 1997;275:523-527.
-
(1997)
Science
, vol.275
, pp. 523-527
-
-
Perkins, N.D.1
Felzien, L.K.2
Betts, J.C.3
Leung, K.4
Beach, D.H.5
Nabel, G.J.6
-
49
-
-
0030764345
-
c-Rel arrests the proliferation of HeLa cells and affects critical regulators of the G1/S-phase transition
-
Bash J, Zong WX, Gelinas C. c-Rel arrests the proliferation of HeLa cells and affects critical regulators of the G1/S-phase transition. Mol Cell Biol. 1997;17:6526-6536.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 6526-6536
-
-
Bash, J.1
Zong, W.X.2
Gelinas, C.3
-
50
-
-
0033199867
-
Inhibition of nuclear factor-kappaB activation confers sensitivity to tumor necrosis factor-alpha by impairment of cell cycle progression in human glioma cells
-
Otsuka G, Nagaya T, Saito K, Mizuno M, Yoshida J, Seo H. Inhibition of nuclear factor-kappaB activation confers sensitivity to tumor necrosis factor-alpha by impairment of cell cycle progression in human glioma cells. Cancer Res. 1999; 59:4446-4452.
-
(1999)
Cancer Res
, vol.59
, pp. 4446-4452
-
-
Otsuka, G.1
Nagaya, T.2
Saito, K.3
Mizuno, M.4
Yoshida, J.5
Seo, H.6
-
51
-
-
0033609170
-
Repression of NF-kappaB impairs HeLa cell proliferation by functional interference with cell cycle checkpoint regulators
-
Kaltschmidt B, Kaltschmidt C, Hehner SP, Droge W, Schmitz ML. Repression of NF-kappaB impairs HeLa cell proliferation by functional interference with cell cycle checkpoint regulators. Oncogene. 1999;18:3213-3225.
-
(1999)
Oncogene
, vol.18
, pp. 3213-3225
-
-
Kaltschmidt, B.1
Kaltschmidt, C.2
Hehner, S.P.3
Droge, W.4
Schmitz, M.L.5
-
52
-
-
0034744949
-
NF-kappaB and cell-cycle regulation: The cyclin connection
-
Joyce D, Albanese C, Steer J, Fu M, Bouzahzah B, Pestell RG. NF-kappaB and cell-cycle regulation: the cyclin connection. Cytokine Growth Factor Rev. 2001;12:73-90.
-
(2001)
Cytokine Growth Factor Rev
, vol.12
, pp. 73-90
-
-
Joyce, D.1
Albanese, C.2
Steer, J.3
Fu, M.4
Bouzahzah, B.5
Pestell, R.G.6
-
53
-
-
0026526437
-
E2F: A link between the Rb tumor suppressor protein and viral oncoproteins
-
Nevins JR. E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science. 1992;258:424-429.
-
(1992)
Science
, vol.258
, pp. 424-429
-
-
Nevins, J.R.1
-
54
-
-
0028988585
-
Inhibitors of mammalian G1 cyclin-dependent kinases
-
Sherr CJ, Roberts JM. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. 1995;9:1149-1163.
-
(1995)
Genes Dev
, vol.9
, pp. 1149-1163
-
-
Sherr, C.J.1
Roberts, J.M.2
-
55
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
Weinberg RA. The retinoblastoma protein and cell cycle control. Cell. 1995;81:323-330.
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.A.1
-
56
-
-
0033596128
-
Multiple mutations contribute to the oncogenicity of the retroviral oncoprotein v-Rel
-
Gilmore TD. Multiple mutations contribute to the oncogenicity of the retroviral oncoprotein v-Rel. Oncogene. 1999; 18:6925-6937.
-
(1999)
Oncogene
, vol.18
, pp. 6925-6937
-
-
Gilmore, T.D.1
-
57
-
-
0025087549
-
Characterization of a novel promoter insertion in the c-rel locus
-
Kabrun N, Bumstead N, Hayman ML, Enrietto PJ. Characterization of a novel promoter insertion in the c-rel locus. Mol Cell Biol. 1990;10:4788-4794.
-
(1990)
Mol Cell Biol
, vol.10
, pp. 4788-4794
-
-
Kabrun, N.1
Bumstead, N.2
Hayman, M.L.3
Enrietto, P.J.4
-
58
-
-
0027729892
-
High levels of c-rel expression are associated with programmed cell death in the developing avian embryo and in bone marrow cells in vitro
-
Abbadie C, Kabrun N, Bouali F, et al. High levels of c-rel expression are associated with programmed cell death in the developing avian embryo and in bone marrow cells in vitro. Cell. 1993;75:899-912.
-
(1993)
Cell
, vol.75
, pp. 899-912
-
-
Abbadie, C.1
Kabrun, N.2
Bouali, F.3
-
59
-
-
0028265304
-
In vivo evolution of c-rel oncogenic potential
-
Hrdlickova R, Nehyba J, Humphries EH. In vivo evolution of c-rel oncogenic potential. J Virol. 1994;68:2371-2382.
-
(1994)
J Virol
, vol.68
, pp. 2371-2382
-
-
Hrdlickova, R.1
Nehyba, J.2
Humphries, E.H.3
-
60
-
-
0028345720
-
Transformation of avian fibroblasts overexpressing the c-rel protooncogene and a variant of c-rel lacking 40 C-terminal amino acids
-
Kralova J, Schatzle JD, Bargmann W, Bose HR Jr. Transformation of avian fibroblasts overexpressing the c-rel protooncogene and a variant of c-rel lacking 40 C-terminal amino acids. J Virol. 1994;68:2073-2083.
-
(1994)
J Virol
, vol.68
, pp. 2073-2083
-
-
Kralova, J.1
Schatzle, J.D.2
Bargmann, W.3
Bose Jr., H.R.4
-
61
-
-
0028209815
-
Evolution of the oncogenic potential of v-rel: Rel-induced expression of immunoregulatory receptors correlates with tumor development and in vitro transformation
-
Nehyba J, Hrdlickova R, Humphries EH. Evolution of the oncogenic potential of v-rel: rel-induced expression of immunoregulatory receptors correlates with tumor development and in vitro transformation. J Virol. 1994;68:2039-2050.
-
(1994)
J Virol
, vol.68
, pp. 2039-2050
-
-
Nehyba, J.1
Hrdlickova, R.2
Humphries, E.H.3
-
62
-
-
0023875871
-
Regional localization of the human c-rel locus using translocation chromosome analysis
-
Brownell E, Fell HP, Tucker PW, Geurts van Kessel AH, Hagemeijer A, Rice NR. Regional localization of the human c-rel locus using translocation chromosome analysis. Oncogene. 1988;2:527-529.
-
(1988)
Oncogene
, vol.2
, pp. 527-529
-
-
Brownell, E.1
Fell, H.P.2
Tucker, P.W.3
Geurts Van Kessel, A.H.4
Hagemeijer, A.5
Rice, N.R.6
-
63
-
-
0027499374
-
Chromosomal localization of genes encoding the transcription factors, c-rel, NF-kappa Bp50, NF-kappa Bp65, and lyt-10 by fluorescence in situ hybridization
-
Mathew S, Murty VV, Dalla-Favera R, Chaganti RS. Chromosomal localization of genes encoding the transcription factors, c-rel, NF-kappa Bp50, NF-kappa Bp65, and lyt-10 by fluorescence in situ hybridization. Oncogene. 1993;8:191-193.
-
(1993)
Oncogene
, vol.8
, pp. 191-193
-
-
Mathew, S.1
Murty, V.V.2
Dalla-Favera, R.3
Chaganti, R.S.4
-
64
-
-
2642609468
-
Characteristic pattern of chromosomal gains and losses in primary large B-cell lymphomas of the gastrointestinal tract
-
Barth TF, Dohner H, Werner CA, et al. Characteristic pattern of chromosomal gains and losses in primary large B-cell lymphomas of the gastrointestinal tract. Blood. 1998;91:4321-4330.
-
(1998)
Blood
, vol.91
, pp. 4321-4330
-
-
Barth, T.F.1
Dohner, H.2
Werner, C.A.3
-
65
-
-
0030052683
-
REL proto-oncogene is frequently amplified in extranodal diffuse large cell lymphoma
-
Houldsworth J, Mathew S, Rao PH, et al. REL proto-oncogene is frequently amplified in extranodal diffuse large cell lymphoma. Blood. 1996;87:25-29.
-
(1996)
Blood
, vol.87
, pp. 25-29
-
-
Houldsworth, J.1
Mathew, S.2
Rao, P.H.3
-
66
-
-
18744421982
-
Chromosomal and gene amplification in diffuse large B-cell lymphoma
-
Rao PH, Houldsworth J, Dyomina K, et al. Chromosomal and gene amplification in diffuse large B-cell lymphoma. Blood. 1998;92:234-240.
-
(1998)
Blood
, vol.92
, pp. 234-240
-
-
Rao, P.H.1
Houldsworth, J.2
Dyomina, K.3
-
67
-
-
0030041048
-
Primary mediastinal (thymic) B-cell lymphoma is characterized by gains of chromosomal material including 9p and amplification of the REL gene
-
Joos S, Otano-Joos MI, Ziegler S, et al. Primary mediastinal (thymic) B-cell lymphoma is characterized by gains of chromosomal material including 9p and amplification of the REL gene. Blood. 1996;87:1571-1578.
-
(1996)
Blood
, vol.87
, pp. 1571-1578
-
-
Joos, S.1
Otano-Joos, M.I.2
Ziegler, S.3
-
68
-
-
0025823675
-
Alterations at the rel locus in human lymphoma
-
Lu D, Thompson JD, Gorski GK, Rice NR, Mayer MG, Yunis JJ. Alterations at the rel locus in human lymphoma. Oncogene. 1991;6:1235-1241.
-
(1991)
Oncogene
, vol.6
, pp. 1235-1241
-
-
Lu, D.1
Thompson, J.D.2
Gorski, G.K.3
Rice, N.R.4
Mayer, M.G.5
Yunis, J.J.6
-
69
-
-
0032489825
-
Multiple hemopoietic defects and lymphoid hyperplasia in mice lacking the transcriptional activation domain of the c-Rel protein
-
Carrasco D, Cheng J, Lewin A, et al. Multiple hemopoietic defects and lymphoid hyperplasia in mice lacking the transcriptional activation domain of the c-Rel protein. J Exp Med. 1998;187:973-984.
-
(1998)
J Exp Med
, vol.187
, pp. 973-984
-
-
Carrasco, D.1
Cheng, J.2
Lewin, A.3
-
70
-
-
0028960452
-
Interaction of the COOH-terminal transactivation domain of p65 NF-kappa B with TATA-binding protein, transcription factor IIB, and coactivators
-
Schmitz ML, Stelzer G, Altmann H, Meisterernst M, Baeuerle PA. Interaction of the COOH-terminal transactivation domain of p65 NF-kappa B with TATA-binding protein, transcription factor IIB, and coactivators. J Biol Chem. 1995;270: 7219-7226.
-
(1995)
J Biol Chem
, vol.270
, pp. 7219-7226
-
-
Schmitz, M.L.1
Stelzer, G.2
Altmann, H.3
Meisterernst, M.4
Baeuerle, P.A.5
-
71
-
-
0027364972
-
Functional interaction of the v-Rel and c-Rel oncoproteins with the TATA-binding protein and association with transcription factor IIB
-
Xu X, Prorock C, Ishikawa H, Maldonado E, Ito Y, Gelinas C. Functional interaction of the v-Rel and c-Rel oncoproteins with the TATA-binding protein and association with transcription factor IIB. Mol Cell Biol. 1993;13:6733-6741.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 6733-6741
-
-
Xu, X.1
Prorock, C.2
Ishikawa, H.3
Maldonado, E.4
Ito, Y.5
Gelinas, C.6
-
72
-
-
0029059060
-
Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B
-
Beg AA, Sha WC, Bronson RT, Ghosh S, Baltimore D. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B. Nature. 1995;376:167-170.
-
(1995)
Nature
, vol.376
, pp. 167-170
-
-
Beg, A.A.1
Sha, W.C.2
Bronson, R.T.3
Ghosh, S.4
Baltimore, D.5
-
73
-
-
0031039111
-
Identification of a tumor-associated mutant form of the NF-kappaB RelA gene with reduced DNA-binding and transactivating activities
-
Trecca D, Guerrini L, Fracchiolla NS, et al. Identification of a tumor-associated mutant form of the NF-kappaB RelA gene with reduced DNA-binding and transactivating activities. Oncogene. 1997;14:791-799.
-
(1997)
Oncogene
, vol.14
, pp. 791-799
-
-
Trecca, D.1
Guerrini, L.2
Fracchiolla, N.S.3
-
74
-
-
0026636897
-
Related subunits of NF-kappa B map to two distinct loci associated with translocations in leukemia, NFKB1 and NFKB2
-
Liptay S, Schmid RM, Perkins ND, et al. Related subunits of NF-kappa B map to two distinct loci associated with translocations in leukemia, NFKB1 and NFKB2. Genomics. 1992; 13:287-292.
-
(1992)
Genomics
, vol.13
, pp. 287-292
-
-
Liptay, S.1
Schmid, R.M.2
Perkins, N.D.3
-
75
-
-
0033611559
-
Physical interaction of the bHLH LYL1 protein and NF-kappaB1 p105
-
Ferrier R, Nougarede R, Doucet S, Kahn-Perles B, Imbert J, Mathieu-Mahul D. Physical interaction of the bHLH LYL1 protein and NF-kappaB1 p105. Oncogene. 1999;18:995-1005.
-
(1999)
Oncogene
, vol.18
, pp. 995-1005
-
-
Ferrier, R.1
Nougarede, R.2
Doucet, S.3
Kahn-Perles, B.4
Imbert, J.5
Mathieu-Mahul, D.6
-
76
-
-
0027305464
-
Structural alterations of the NF-kappa B transcription factor lyt-10 in lymphoid malignancies
-
Fracchiolla NS, Lombardi L, Salina M, et al. Structural alterations of the NF-kappa B transcription factor lyt-10 in lymphoid malignancies. Oncogene. 1993;8:2839-2845.
-
(1993)
Oncogene
, vol.8
, pp. 2839-2845
-
-
Fracchiolla, N.S.1
Lombardi, L.2
Salina, M.3
-
77
-
-
0028033909
-
Heterogeneous chromosomal aberrations generate 3' truncations of the NFKB2/lyt-10 gene in lymphoid malignancies
-
Migliazza A, Lombardi L, Rocchi M, et al. Heterogeneous chromosomal aberrations generate 3' truncations of the NFKB2/lyt-10 gene in lymphoid malignancies. Blood. 1994; 84:3850-3860.
-
(1994)
Blood
, vol.84
, pp. 3850-3860
-
-
Migliazza, A.1
Lombardi, L.2
Rocchi, M.3
-
78
-
-
0026331456
-
B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kappa B p50
-
Neri A, Chang CC, Lombardi L, et al. B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kappa B p50. Cell. 1991; 67:1075-1087.
-
(1991)
Cell
, vol.67
, pp. 1075-1087
-
-
Neri, A.1
Chang, C.C.2
Lombardi, L.3
-
79
-
-
0028306320
-
Rearrangement and altered expression of the NFKB-2 gene in human cutaneous T-lymphoma cells
-
Thakur S, Lin HC, Tseng WT, et al. Rearrangement and altered expression of the NFKB-2 gene in human cutaneous T-lymphoma cells. Oncogene. 1994;9:2335-2344.
-
(1994)
Oncogene
, vol.9
, pp. 2335-2344
-
-
Thakur, S.1
Lin, H.C.2
Tseng, W.T.3
-
80
-
-
0029133328
-
Rearranged NFKB-2 genes in lymphoid neoplasms code for constitutively active nuclear transactivators
-
Chang CC, Zhang J, Lombardi L, Neri A, Dalla-Favera R. Rearranged NFKB-2 genes in lymphoid neoplasms code for constitutively active nuclear transactivators. Mol Cell Biol. 1995;15:5180-5187.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 5180-5187
-
-
Chang, C.C.1
Zhang, J.2
Lombardi, L.3
Neri, A.4
Dalla-Favera, R.5
-
81
-
-
0028360163
-
Rearranged NFKB2 gene in the HUT78 T-lymphoma cell line codes for a constitutively nuclear factor lacking transcriptional repressor functions
-
Zhang J, Chang CC, Lombardi L, Dalla-Favera R. Rearranged NFKB2 gene in the HUT78 T-lymphoma cell line codes for a constitutively nuclear factor lacking transcriptional repressor functions. Oncogene. 1994;9:1931-1937.
-
(1994)
Oncogene
, vol.9
, pp. 1931-1937
-
-
Zhang, J.1
Chang, C.C.2
Lombardi, L.3
Dalla-Favera, R.4
-
82
-
-
0031985287
-
Nuclear factor (NF)-kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responses
-
Caamano JH, Rizzo CA, Durham SK, et al. Nuclear factor (NF)-kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responses. J Exp Med. 1998;187:185-196.
-
(1998)
J Exp Med
, vol.187
, pp. 185-196
-
-
Caamano, J.H.1
Rizzo, C.A.2
Durham, S.K.3
-
83
-
-
0031964855
-
Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture
-
Franzoso G, Carlson L, Poljak L, et al. Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture. J Exp Med. 1998;187:147-159.
-
(1998)
J Exp Med
, vol.187
, pp. 147-159
-
-
Franzoso, G.1
Carlson, L.2
Poljak, L.3
-
84
-
-
0030763645
-
Gastric hyperplasia and increased proliferative responses of lymphocytes in mice lacking the COOH-terminal ankyrin domain of NF-kappaB2
-
Ishikawa H, Carrasco D, Claudio E, Ryseck RP, Bravo R. Gastric hyperplasia and increased proliferative responses of lymphocytes in mice lacking the COOH-terminal ankyrin domain of NF-kappaB2. J Exp Med. 1997;186:999-1014.
-
(1997)
J Exp Med
, vol.186
, pp. 999-1014
-
-
Ishikawa, H.1
Carrasco, D.2
Claudio, E.3
Ryseck, R.P.4
Bravo, R.5
-
85
-
-
0033596126
-
Diverse agents act at multiple levels to inhibit the Rel/NF-kappaB signal transduction pathway
-
Epinat JC, Gilmore TD. Diverse agents act at multiple levels to inhibit the Rel/NF-kappaB signal transduction pathway. Oncogene. 1999;18:6896-6909.
-
(1999)
Oncogene
, vol.18
, pp. 6896-6909
-
-
Epinat, J.C.1
Gilmore, T.D.2
-
86
-
-
43949155604
-
Bcl-3-mediated nuclear regulation of the NF-kappa B trans-activating factor
-
Lenardo M, Siebenlist U. Bcl-3-mediated nuclear regulation of the NF-kappa B trans-activating factor. Immunol Today. 1994;15:145-147.
-
(1994)
Immunol Today
, vol.15
, pp. 145-147
-
-
Lenardo, M.1
Siebenlist, U.2
-
87
-
-
0025324450
-
The candidate protooncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control
-
Ohno H, Takimoto G, McKeithan TW. The candidate protooncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control. Cell. 1990;60:991-997.
-
(1990)
Cell
, vol.60
, pp. 991-997
-
-
Ohno, H.1
Takimoto, G.2
McKeithan, T.W.3
-
88
-
-
9044243016
-
BCL3 rearrangement and t(14;19)(q32;q13) in lymphoproliferative disorders
-
Michaux L, Mecucci C, Stul M, et al. BCL3 rearrangement and t(14;19)(q32;q13) in lymphoproliferative disorders. Genes Chromosomes Cancer. 1996;15:38-47.
-
(1996)
Genes Chromosomes Cancer
, vol.15
, pp. 38-47
-
-
Michaux, L.1
Mecucci, C.2
Stul, M.3
-
89
-
-
0027756678
-
Molecular characterization of the t(14;19)(q32;q13) translocation in chronic lymphocytic leukemia
-
Ohno H, Doi S, Yabumoto K, Fukuhara S, McKeithan TW. Molecular characterization of the t(14;19)(q32;q13) translocation in chronic lymphocytic leukemia. Leukemia. 1993;7: 2057-2063.
-
(1993)
Leukemia
, vol.7
, pp. 2057-2063
-
-
Ohno, H.1
Doi, S.2
Yabumoto, K.3
Fukuhara, S.4
McKeithan, T.W.5
-
90
-
-
17144433112
-
Critical roles for the Bcl-3 oncoprotein in T cell-mediated immunity, splenic microarchitecture, and germinal center reactions
-
Franzoso G, Carlson L, Scharton-Kersten T, et al. Critical roles for the Bcl-3 oncoprotein in T cell-mediated immunity, splenic microarchitecture, and germinal center reactions. Immunity. 1997;6:479-490.
-
(1997)
Immunity
, vol.6
, pp. 479-490
-
-
Franzoso, G.1
Carlson, L.2
Scharton-Kersten, T.3
-
91
-
-
0029665444
-
Constitutive expression of Bcl-3 in thymocytes increases the DNA binding of NF-kappaB1 (p50) homodimers in vivo
-
Caamano JH, Perez P, Lira SA, Bravo R. Constitutive expression of Bcl-3 in thymocytes increases the DNA binding of NF-kappaB1 (p50) homodimers in vivo. Mol Cell Biol. 1996; 16:1342-1348.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1342-1348
-
-
Caamano, J.H.1
Perez, P.2
Lira, S.A.3
Bravo, R.4
-
92
-
-
0032493106
-
Lymphadenopathy, splenomegaly, and altered immunoglobulin production in BCL3 transgenic mice
-
Ong ST, Hackbarth ML, Degenstein LC, Baunoch DA, Anastasi J, McKeithan TW. Lymphadenopathy, splenomegaly, and altered immunoglobulin production in BCL3 transgenic mice. Oncogene. 1998;16:2333-2343.
-
(1998)
Oncogene
, vol.16
, pp. 2333-2343
-
-
Ong, S.T.1
Hackbarth, M.L.2
Degenstein, L.C.3
Baunoch, D.A.4
Anastasi, J.5
McKeithan, T.W.6
-
93
-
-
0033595893
-
How NF-kappaB is activated: The role of the IkappaB kinase (IKK) complex
-
Karin M. How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex. Oncogene. 1999;18:6867-6874.
-
(1999)
Oncogene
, vol.18
, pp. 6867-6874
-
-
Karin, M.1
-
94
-
-
0028172914
-
Disruption of I kappa B alpha regulation by antisense RNA expression leads to malignant transformation
-
Beauparlant P, Kwan I, Bitar R, et al. Disruption of I kappa B alpha regulation by antisense RNA expression leads to malignant transformation. Oncogene. 1994;9:3189-3197.
-
(1994)
Oncogene
, vol.9
, pp. 3189-3197
-
-
Beauparlant, P.1
Kwan, I.2
Bitar, R.3
-
95
-
-
0028971291
-
Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice
-
Beg AA, Sha WC, Bronson RT, Baltimore D. Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice. Genes Dev. 1995;9:2736-2746.
-
(1995)
Genes Dev
, vol.9
, pp. 2736-2746
-
-
Beg, A.A.1
Sha, W.C.2
Bronson, R.T.3
Baltimore, D.4
-
96
-
-
0029664657
-
IkappaBalpha deficiency results in a sustained NF-kappaB response and severe wide-spread dermatitis in mice
-
Klement JF, Rice NR, Car BD, et al. IkappaBalpha deficiency results in a sustained NF-kappaB response and severe wide-spread dermatitis in mice. Mol Cell Biol. 1996;16:2341-2349.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 2341-2349
-
-
Klement, J.F.1
Rice, N.R.2
Car, B.D.3
-
97
-
-
0033587084
-
Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha
-
Cabannes E, Khan G, Aillet F, Jarrett RF, Hay RT. Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha. Oncogene. 1999;18:3063-3070.
-
(1999)
Oncogene
, vol.18
, pp. 3063-3070
-
-
Cabannes, E.1
Khan, G.2
Aillet, F.3
Jarrett, R.F.4
Hay, R.T.5
-
98
-
-
0032559888
-
Defective IkappaBalpha in Hodgkin cell lines with constitutively active NF-kappaB
-
Wood KM, Roff M, Hay RT. Defective IkappaBalpha in Hodgkin cell lines with constitutively active NF-kappaB. Oncogene. 1998;16:2131-2139.
-
(1998)
Oncogene
, vol.16
, pp. 2131-2139
-
-
Wood, K.M.1
Roff, M.2
Hay, R.T.3
-
99
-
-
0033558614
-
Elevated constitutive IkappaB kinase activity and IkappaB-alpha phosphorylation in Hs294T melanoma cells lead to increased basal MGSA/GRO-alpha transcription
-
Devalaraja MN, Wang DZ, Ballard DW, Richmond A. Elevated constitutive IkappaB kinase activity and IkappaB-alpha phosphorylation in Hs294T melanoma cells lead to increased basal MGSA/GRO-alpha transcription. Cancer Res. 1999;59:1372-1377.
-
(1999)
Cancer Res
, vol.59
, pp. 1372-1377
-
-
Devalaraja, M.N.1
Wang, D.Z.2
Ballard, D.W.3
Richmond, A.4
-
100
-
-
0033603461
-
Negative regulation of transactivation function but not DNA binding of NF-kappaB and AP-1 by IkappaBbetal in breast cancer cells
-
Newton TR, Patel NM, Bhat-Nakshatri P, Stauss CR, Goulet RJ Jr., Nakshatri H. Negative regulation of transactivation function but not DNA binding of NF-kappaB and AP-1 by IkappaBbetal in breast cancer cells. J Biol Chem. 1999;274: 18827-18835.
-
(1999)
J Biol Chem
, vol.274
, pp. 18827-18835
-
-
Newton, T.R.1
Patel, N.M.2
Bhat-Nakshatri, P.3
Stauss, C.R.4
Goulet Jr., R.J.5
Nakshatri, H.6
-
101
-
-
0026485510
-
Chromosomal localization of the genes encoding the p50/p105 subunits of NF-kappa B (NFKB2) and the I kappa B/MAD-3 (NFKB1) inhibitor of NF-kappa B to 4q24 and 14q13, respectively
-
Le Beau MM, Ito C, Cogswell P, Espinosa R III, Fernald AA, Baldwin AS Jr. Chromosomal localization of the genes encoding the p50/p105 subunits of NF-kappa B (NFKB2) and the I kappa B/MAD-3 (NFKB1) inhibitor of NF-kappa B to 4q24 and 14q13, respectively. Genomics. 1992;14:529-531.
-
(1992)
Genomics
, vol.14
, pp. 529-531
-
-
Le Beau, M.M.1
Ito, C.2
Cogswell, P.3
Espinosa III, R.4
Fernald, A.A.5
Baldwin Jr., A.S.6
-
102
-
-
0027169549
-
Phenotypic and genotypic characterization of Hodgkin's disease
-
Koduru PR, Susin M, Schulman P, et al. Phenotypic and genotypic characterization of Hodgkin's disease. Am J Hematol. 1993;44:117-124.
-
(1993)
Am J Hematol
, vol.44
, pp. 117-124
-
-
Koduru, P.R.1
Susin, M.2
Schulman, P.3
-
103
-
-
0030006437
-
High-level nuclear NF-kappa B and Oct-2 is a common feature of cultured Hodgkin/Reed-Sternberg cells
-
Bargou RC, Leng C, Krappmann D, et al. High-level nuclear NF-kappa B and Oct-2 is a common feature of cultured Hodgkin/Reed-Sternberg cells. Blood. 1996;87:4340-4347.
-
(1996)
Blood
, vol.87
, pp. 4340-4347
-
-
Bargou, R.C.1
Leng, C.2
Krappmann, D.3
-
104
-
-
0030939504
-
Hodgkin's disease: A tumor with disturbed immunological pathways
-
Gruss HJ, Pinto A, Duyster J, Poppema S, Herrmann F. Hodgkin's disease: a tumor with disturbed immunological pathways. Immunol Today. 1997;18:156-163.
-
(1997)
Immunol Today
, vol.18
, pp. 156-163
-
-
Gruss, H.J.1
Pinto, A.2
Duyster, J.3
Poppema, S.4
Herrmann, F.5
-
105
-
-
0035525784
-
Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines
-
Fiumara P, Snell V, Li Y, et al. Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines. Blood. 2001;98:2784-2790.
-
(2001)
Blood
, vol.98
, pp. 2784-2790
-
-
Fiumara, P.1
Snell, V.2
Li, Y.3
-
106
-
-
0037409887
-
Nuclear transcription factor-kappaB in Hodgkin's disease
-
Younes A, Garg A, Aggarwal BB. Nuclear transcription factor-kappaB in Hodgkin's disease. Leuk Lymphoma. 2003;44: 929-935.
-
(2003)
Leuk Lymphoma
, vol.44
, pp. 929-935
-
-
Younes, A.1
Garg, A.2
Aggarwal, B.B.3
-
107
-
-
0034092559
-
Transcription factor NF-kappaB is constitutively activated in acute lymphoblastic leukemia cells
-
Kordes U, Krappmann D, Heissmeyer V, Ludwig WD, Scheidereit C. Transcription factor NF-kappaB is constitutively activated in acute lymphoblastic leukemia cells. Leukemia. 2000;14:399-402.
-
(2000)
Leukemia
, vol.14
, pp. 399-402
-
-
Kordes, U.1
Krappmann, D.2
Heissmeyer, V.3
Ludwig, W.D.4
Scheidereit, C.5
-
108
-
-
0032034216
-
A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation
-
Reuther JY, Reuther GW, Cortez D, Pendergast AM, Baldwin AS Jr. A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation. Genes Dev. 1998;12:968-981.
-
(1998)
Genes Dev
, vol.12
, pp. 968-981
-
-
Reuther, J.Y.1
Reuther, G.W.2
Cortez, D.3
Pendergast, A.M.4
Baldwin Jr., A.S.5
-
109
-
-
0033580229
-
Binding of c-Rel to STAT5 target sequences in HTLV-1-transformed T cells
-
Sun SC, Maggirwar SB, Harhaj EW, Uhlik M. Binding of c-Rel to STAT5 target sequences in HTLV-1-transformed T cells. Oncogene. 1999;18:1401-1409.
-
(1999)
Oncogene
, vol.18
, pp. 1401-1409
-
-
Sun, S.C.1
Maggirwar, S.B.2
Harhaj, E.W.3
Uhlik, M.4
-
110
-
-
0036771841
-
Increased IkappaB kinase activity is associated with activated NF-kappaB in acute myeloid blasts
-
Baumgartner B, Weber M, Quirling M, et al. Increased IkappaB kinase activity is associated with activated NF-kappaB in acute myeloid blasts. Leukemia. 2002;16:2062-2071.
-
(2002)
Leukemia
, vol.16
, pp. 2062-2071
-
-
Baumgartner, B.1
Weber, M.2
Quirling, M.3
-
111
-
-
0033120826
-
Constitutive activation of NF-kappaB in primary adult T-cell leukemia cells
-
Mori N, Fujii M, Ikeda S, Yamada Y, Tomonaga M, Ballard DW, et al. Constitutive activation of NF-kappaB in primary adult T-cell leukemia cells. Blood. 1999;93:2360-2368.
-
(1999)
Blood
, vol.93
, pp. 2360-2368
-
-
Mori, N.1
Fujii, M.2
Ikeda, S.3
Yamada, Y.4
Tomonaga, M.5
Ballard, D.W.6
-
112
-
-
0035371244
-
Soy isoflavone supplementation in healthy men prevents NF-kappa B activation by TNF-alpha in blood lymphocytes
-
Davis IN, Kucuk O, Djuric Z, Sarkar FH. Soy isoflavone supplementation in healthy men prevents NF-kappa B activation by TNF-alpha in blood lymphocytes. Free Radic Biol Med. 2001;30:1293-1302.
-
(2001)
Free Radic Biol Med
, vol.30
, pp. 1293-1302
-
-
Davis, I.N.1
Kucuk, O.2
Djuric, Z.3
Sarkar, F.H.4
-
113
-
-
0035886024
-
Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells
-
Guzman ML, Neering SJ, Upchurch D, et al. Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells. Blood. 2001;98:2301-2307.
-
(2001)
Blood
, vol.98
, pp. 2301-2307
-
-
Guzman, M.L.1
Neering, S.J.2
Upchurch, D.3
-
114
-
-
0034651739
-
Modulation of NF-kappa B activity and apoptosis in chronic lymphocytic leukemia B cells
-
Furman RR, Asgary Z, Mascarenhas JO, Liou HC, Schatmer EJ. Modulation of NF-kappa B activity and apoptosis in chronic lymphocytic leukemia B cells. J Immunol. 2000;164: 2200-2206.
-
(2000)
J Immunol
, vol.164
, pp. 2200-2206
-
-
Furman, R.R.1
Asgary, Z.2
Mascarenhas, J.O.3
Liou, H.C.4
Schatmer, E.J.5
-
115
-
-
0034941816
-
The role of Epstein-Barr virus in neoplastic transformation
-
Knecht H, Berger C, Rothenberger S, Odermatt BF, Brousset P. The role of Epstein-Barr virus in neoplastic transformation. Oncology, 2001;60:289-302.
-
(2001)
Oncology
, vol.60
, pp. 289-302
-
-
Knecht, H.1
Berger, C.2
Rothenberger, S.3
Odermatt, B.F.4
Brousset, P.5
-
116
-
-
0037711690
-
Mechanisms of Bcr-Abl-mediated NF-kappaB/Rel activation
-
Kirchner D, Duyster J, Ottmann O, Schmid RM, Bergmann L, Munzert G. Mechanisms of Bcr-Abl-mediated NF-kappaB/Rel activation. Exp Hematol. 2003;31:504-511.
-
(2003)
Exp Hematol
, vol.31
, pp. 504-511
-
-
Kirchner, D.1
Duyster, J.2
Ottmann, O.3
Schmid, R.M.4
Bergmann, L.5
Munzert, G.6
-
117
-
-
0038206722
-
Inhibition of constitutive NF-kappaB activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis
-
Pham LV, Tamayo AT, Yoshimura LC, Lo P, Ford RJ. Inhibition of constitutive NF-kappaB activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis. J Immunol. 2003;171:88-95.
-
(2003)
J Immunol
, vol.171
, pp. 88-95
-
-
Pham, L.V.1
Tamayo, A.T.2
Yoshimura, L.C.3
Lo, P.4
Ford, R.J.5
-
118
-
-
0037336974
-
Cytokine modulation of nuclear factor-kappaB activity in B-chronic lymphocytic leukemia
-
Zaninoni A, Imperiali FG, Pasquini C, Zanella A, Barcellini W. Cytokine modulation of nuclear factor-kappaB activity in B-chronic lymphocytic leukemia. Exp Hematol. 2003;31:185-190.
-
(2003)
Exp Hematol
, vol.31
, pp. 185-190
-
-
Zaninoni, A.1
Imperiali, F.G.2
Pasquini, C.3
Zanella, A.4
Barcellini, W.5
-
119
-
-
0035433110
-
Bcl10 expression, rearrangement and mutation in MALT lymphoma: Correlation with expression of nuclear factor-kappaB
-
Ohshima K, Muta H, Kawasaki C, et al. Bcl10 expression, rearrangement and mutation in MALT lymphoma: correlation with expression of nuclear factor-kappaB. Int J Oncol. 2001;19:283-289.
-
(2001)
Int J Oncol
, vol.19
, pp. 283-289
-
-
Ohshima, K.1
Muta, H.2
Kawasaki, C.3
-
120
-
-
17744386318
-
Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure
-
Ruland J, Duncan GS, Elia A, et al. Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure. Cell. 2001;104:33-42.
-
(2001)
Cell
, vol.104
, pp. 33-42
-
-
Ruland, J.1
Duncan, G.S.2
Elia, A.3
-
121
-
-
0034646672
-
Regulatory mechanisms of TRAF2-mediated signal transduction by Bcl10, a MALT lymphoma-associated protein
-
Yoneda T, Imaizumi K, Maeda M, et al. Regulatory mechanisms of TRAF2-mediated signal transduction by Bcl10, a MALT lymphoma-associated protein. J Biol Chem. 2000;275: 11114-11120.
-
(2000)
J Biol Chem
, vol.275
, pp. 11114-11120
-
-
Yoneda, T.1
Imaizumi, K.2
Maeda, M.3
-
122
-
-
0032487857
-
The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta
-
Yin MJ, Yamamoto Y, Gaynor RB. The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta. Nature. 1998;396:77-80.
-
(1998)
Nature
, vol.396
, pp. 77-80
-
-
Yin, M.J.1
Yamamoto, Y.2
Gaynor, R.B.3
-
123
-
-
0034578521
-
Comparative studies on the suppression of nitric oxide synthase by curcumin and its hydrogenated metabolites through down-regulation of IkappaB kinase and NFkappaB activation in macrophages
-
Pan MH, Lin-Shiau SY, Lin JK. Comparative studies on the suppression of nitric oxide synthase by curcumin and its hydrogenated metabolites through down-regulation of IkappaB kinase and NFkappaB activation in macrophages. Biochem Pharmacol. 2000;60:1665-1676.
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 1665-1676
-
-
Pan, M.H.1
Lin-Shiau, S.Y.2
Lin, J.K.3
-
124
-
-
0037305821
-
Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis
-
Bharti AC, Donato N, Singh S, Aggarwal BB. Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis. Blood. 2003;101: 1053-1062.
-
(2003)
Blood
, vol.101
, pp. 1053-1062
-
-
Bharti, A.C.1
Donato, N.2
Singh, S.3
Aggarwal, B.B.4
-
125
-
-
0032523030
-
Nonselective inhibition of proliferation of transformed and nontransformed cells by the anticancer agent curcumin (diferuloylmethane)
-
Gautam SC, Xu YX, Pindolia KR, Janakiraman N, Chapman RA. Nonselective inhibition of proliferation of transformed and nontransformed cells by the anticancer agent curcumin (diferuloylmethane). Biochem Pharmacol. 1998;55:1333-1337.
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 1333-1337
-
-
Gautam, S.C.1
Xu, Y.X.2
Pindolia, K.R.3
Janakiraman, N.4
Chapman, R.A.5
-
126
-
-
0030823162
-
Helenalin, an anti-inflammatory sesquiterpene lactone from Arnica, selectively inhibits transcription factor NF-kappaB
-
Lyss G, Schmidt TJ, Merfort I, Pahl HL. Helenalin, an anti-inflammatory sesquiterpene lactone from Arnica, selectively inhibits transcription factor NF-kappaB. Biol Chem. 1997; 378:951-961.
-
(1997)
Biol Chem
, vol.378
, pp. 951-961
-
-
Lyss, G.1
Schmidt, T.J.2
Merfort, I.3
Pahl, H.L.4
-
127
-
-
0034871746
-
Cytotoxic sesquiterpene lactones mediate their death-inducing effect in leukemia T cells by triggering apoptosis
-
Dirsch VM, Stuppner H, Vollmar AM. Cytotoxic sesquiterpene lactones mediate their death-inducing effect in leukemia T cells by triggering apoptosis. Planta Med. 2001;67: 557-559.
-
(2001)
Planta Med
, vol.67
, pp. 557-559
-
-
Dirsch, V.M.1
Stuppner, H.2
Vollmar, A.M.3
-
128
-
-
0035422774
-
Helenalin triggers a CD95 death receptor-independent apoptosis that is not affected by overexpression of Bcl-x(L) or Bcl-2
-
Dirsch VM, Stuppner H, Vollmar AM. Helenalin triggers a CD95 death receptor-independent apoptosis that is not affected by overexpression of Bcl-x(L) or Bcl-2. Cancer Res. 2001;61:5817-5823.
-
(2001)
Cancer Res
, vol.61
, pp. 5817-5823
-
-
Dirsch, V.M.1
Stuppner, H.2
Vollmar, A.M.3
-
129
-
-
0037111664
-
Tumor necrosis factor receptor-associated factor 1 gene overexpression in B-cell chronic lymphocytic leukemia: Analysis of NF-kappa B/Rel-regulated inhibitors of apoptosis
-
Munzert G, Kirchner D, Stobbe H, et al. Tumor necrosis factor receptor-associated factor 1 gene overexpression in B-cell chronic lymphocytic leukemia: analysis of NF-kappa B/Rel-regulated inhibitors of apoptosis. Blood. 2002;100:3749-3756.
-
(2002)
Blood
, vol.100
, pp. 3749-3756
-
-
Munzert, G.1
Kirchner, D.2
Stobbe, H.3
-
130
-
-
0034322370
-
Suppression of NF-kappaB activity by sulfasalazine is mediated by direct inhibition of IkappaB kinases alpha and beta
-
Weber CK, Liptay S, Wirth T, Adler G, Schmid RM. Suppression of NF-kappaB activity by sulfasalazine is mediated by direct inhibition of IkappaB kinases alpha and beta. Gastroenterology. 2000;119:1209-1218.
-
(2000)
Gastroenterology
, vol.119
, pp. 1209-1218
-
-
Weber, C.K.1
Liptay, S.2
Wirth, T.3
Adler, G.4
Schmid, R.M.5
-
131
-
-
0042848523
-
Treatment of acute promyelocytic leukemia and other hematologic malignancies with arsenic trioxide: Review of clinical and basic studies
-
Liu P, Han ZC. Treatment of acute promyelocytic leukemia and other hematologic malignancies with arsenic trioxide: review of clinical and basic studies. Int J Hematol. 2003;78: 32-39.
-
(2003)
Int J Hematol
, vol.78
, pp. 32-39
-
-
Liu, P.1
Han, Z.C.2
-
132
-
-
0042744800
-
Inhibition of NF-kappaB essentially contributes to arsenic-induced apoptosis
-
Mathas S, Lietz A, Janz M, et al. Inhibition of NF-kappaB essentially contributes to arsenic-induced apoptosis. Blood. 2003;102:1028-1034.
-
(2003)
Blood
, vol.102
, pp. 1028-1034
-
-
Mathas, S.1
Lietz, A.2
Janz, M.3
-
133
-
-
0041928194
-
Tetrathiomolybdate inhibits angiogenesis and metastasis through suppression of the NFkappaB signaling cascade
-
Pan Q, Bao LW, Merajver SD. Tetrathiomolybdate inhibits angiogenesis and metastasis through suppression of the NFkappaB signaling cascade. Mol Cancer Res. 2003;1:701-706.
-
(2003)
Mol Cancer Res
, vol.1
, pp. 701-706
-
-
Pan, Q.1
Bao, L.W.2
Merajver, S.D.3
-
134
-
-
0035207110
-
The role of nuclear factor-kappaB in the biology and treatment of multiple myeloma
-
Berenson JR, Ma HM, Vescio R. The role of nuclear factor-kappaB in the biology and treatment of multiple myeloma. Semin Oncol. 2001;28:626-633.
-
(2001)
Semin Oncol
, vol.28
, pp. 626-633
-
-
Berenson, J.R.1
Ma, H.M.2
Vescio, R.3
-
135
-
-
0038281345
-
Downstream effectors of oncogenic ras in multiple myeloma cells
-
Hu L, Shi Y, Hsu JH, Gera J, Van Ness B, Lichtenstein A. Downstream effectors of oncogenic ras in multiple myeloma cells. Blood. 2003;101:3126-3135.
-
(2003)
Blood
, vol.101
, pp. 3126-3135
-
-
Hu, L.1
Shi, Y.2
Hsu, J.H.3
Gera, J.4
Van Ness, B.5
Lichtenstein, A.6
-
136
-
-
0242493856
-
The proteasome inhibitor bortezomib interacts synergistically with histone deacetylase inhibitors to induce apoptosis in Bcr/Abl+ cells sensitive and resistant to STI571
-
Yu C, Rahmani M, Conrad D, Subler M, Dent P, Grant S. The proteasome inhibitor bortezomib interacts synergistically with histone deacetylase inhibitors to induce apoptosis in Bcr/Abl+ cells sensitive and resistant to STI571. Blood. 2003; 102:3765-3774.
-
(2003)
Blood
, vol.102
, pp. 3765-3774
-
-
Yu, C.1
Rahmani, M.2
Conrad, D.3
Subler, M.4
Dent, P.5
Grant, S.6
-
138
-
-
0346505340
-
The IKK NF-kappaB system: A treasure trove for drug development
-
Karin M, Yamamoto Y, Wang QM. The IKK NF-kappaB system: a treasure trove for drug development. Nat Rev Drug Discov. 2004;3:17-26.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 17-26
-
-
Karin, M.1
Yamamoto, Y.2
Wang, Q.M.3
-
140
-
-
0037119678
-
Structure-activity relationship studies of ethyl 2-[(3-methyl-2,5-dioxo(3-pyrrolinyl)) amino]-4-(trifluoromethyl)pyrimidine-5-carboxylate: An inhibitor of AP-1 and NF-kappaB mediated gene expression
-
Palanki MS, Gayo-Fung LM, Shevlin GI, et al. Structure-activity relationship studies of ethyl 2-[(3-methyl-2,5-dioxo(3-pyrrolinyl)) amino]-4-(trifluoromethyl)pyrimidine-5-carboxylate: an inhibitor of AP-1 and NF-kappaB mediated gene expression. Bioorg Med Chem Lett. 2002;12:2573-2577.
-
(2002)
Bioorg Med Chem Lett
, vol.12
, pp. 2573-2577
-
-
Palanki, M.S.1
Gayo-Fung, L.M.2
Shevlin, G.I.3
-
142
-
-
0037449711
-
BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice
-
Burke JR, Pattoli MA, Gregor KR, et al. BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice. J Biol Chem. 2003;278:1450-1456.
-
(2003)
J Biol Chem
, vol.278
, pp. 1450-1456
-
-
Burke, J.R.1
Pattoli, M.A.2
Gregor, K.R.3
-
143
-
-
0041355495
-
A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts
-
Kishore N, Sommers C, Mathialagan S, et al. A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts. J Biol Chem. 2003;278:32861-32871.
-
(2003)
J Biol Chem
, vol.278
, pp. 32861-32871
-
-
Kishore, N.1
Sommers, C.2
Mathialagan, S.3
-
144
-
-
1842625594
-
Inhibition of proteasomal function by curcumin induces apoptosis through mitochondrial pathway
-
Dec 30 [Epub ahead of print]
-
Jana NR, Dikshit P, Goswami A, Nukina N. Inhibition of proteasomal function by curcumin induces apoptosis through mitochondrial pathway. J Biol Chem. 2003. Dec 30 [Epub ahead of print].
-
(2003)
J Biol Chem
-
-
Jana, N.R.1
Dikshit, P.2
Goswami, A.3
Nukina, N.4
-
145
-
-
0037316909
-
Modulation of cellular signaling pathways: Prospects for targeted therapy in hematological malignancies
-
Ravandi F, Talpaz M, Estrov Z. Modulation of cellular signaling pathways: prospects for targeted therapy in hematological malignancies. Clin Cancer Res. 2003;9:535-550.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 535-550
-
-
Ravandi, F.1
Talpaz, M.2
Estrov, Z.3
-
146
-
-
0036561385
-
The emerging role of angiogenesis inhibitors in hematologic malignancies
-
Giles FJ. The emerging role of angiogenesis inhibitors in hematologic malignancies. Oncology (Huntingt). 2002;16:23-29.
-
(2002)
Oncology (Huntingt)
, vol.16
, pp. 23-29
-
-
Giles, F.J.1
|