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Volumn 59, Issue 6, 1999, Pages 1372-1377

Elevated constitutive IκB kinase activity and IκB-α phosphorylation in Hs294T melanoma cells lead to increased basal MGSA/GRO-α transcription

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN KINASE; REGULATOR PROTEIN; ALPHA CHEMOKINE; CHEMOTACTIC FACTOR; CHUK PROTEIN, HUMAN; CXCL1 PROTEIN, HUMAN; DNA BINDING PROTEIN; GROWTH PROMOTOR; I KAPPA B; I KAPPA B KINASE; IKBKB PROTEIN, HUMAN; IKBKE PROTEIN, HUMAN; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE;

EID: 0033558614     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (78)

References (54)
  • 1
    • 0000211829 scopus 로고
    • Melanoma growth stimulatory activily: Isolation from human melanoma tumors and characterization of tissue distribution
    • Richmond, A., and Thomas, H. G. Melanoma growth stimulatory activily: isolation from human melanoma tumors and characterization of tissue distribution. J. Cell. Biochem., 36: 185-198, 1988.
    • (1988) J. Cell. Biochem. , vol.36 , pp. 185-198
    • Richmond, A.1    Thomas, H.G.2
  • 2
    • 0024041436 scopus 로고
    • Molecular characterization and chromosomal mapping of melanoma growth stimulatory activity, a growth factor structurally related to β-thromboglobulin
    • Richmond, A. Balentien, E., Thomas, H. G., Flaggs, G., Barton, D. E., Spiess, J., Bordoni, R., Francke, U., and Derynck, R. Molecular characterization and chromosomal mapping of melanoma growth stimulatory activity, a growth factor structurally related to β-thromboglobulin. EMBO J., 7: 2025-2033, 1988.
    • (1988) EMBO J. , vol.7 , pp. 2025-2033
    • Richmond, A.1    Balentien, E.2    Thomas, H.G.3    Flaggs, G.4    Barton, D.E.5    Spiess, J.6    Bordoni, R.7    Francke, U.8    Derynck, R.9
  • 3
    • 0022966376 scopus 로고
    • Purification of melanoma growth stimulatory activity
    • Richmond, A., and Thomas, H. G. Purification of melanoma growth stimulatory activity. J. Cell. Physiol., 129: 315-384, 1986.
    • (1986) J. Cell. Physiol. , vol.129 , pp. 315-384
    • Richmond, A.1    Thomas, H.G.2
  • 4
    • 0022407463 scopus 로고
    • Characterization of autostimulatory and transforming growth factors from human melanoma cells
    • Richmond, A., Lawson, D. H., Nixon, D. W., and Chawla, R. K. Characterization of autostimulatory and transforming growth factors from human melanoma cells. Cancer Res., 45: 6390-6394, 1985.
    • (1985) Cancer Res. , vol.45 , pp. 6390-6394
    • Richmond, A.1    Lawson, D.H.2    Nixon, D.W.3    Chawla, R.K.4
  • 5
    • 0023550277 scopus 로고
    • Constitutive overexpression of a growth-regulated gene in transformed Chinese hamster and human cells
    • Anisowicz, A., Bardwell, L., and Sager, R. Constitutive overexpression of a growth-regulated gene in transformed Chinese hamster and human cells. Proc. Natl. Acad. Sci., USA. 84: 7188-7192, 1987.
    • (1987) Proc. Natl. Acad. Sci., USA , vol.84 , pp. 7188-7192
    • Anisowicz, A.1    Bardwell, L.2    Sager, R.3
  • 6
    • 0025324337 scopus 로고
    • Neutrophil-activating properties of the melanoma growth-stimulatory activity
    • Moser, B., Clark-Lewis, I., Zwahlen, R., and Baggiolini, M. Neutrophil-activating properties of the melanoma growth-stimulatory activity. J. Exp. Med., 171: 1797-1802, 1990.
    • (1990) J. Exp. Med. , vol.171 , pp. 1797-1802
    • Moser, B.1    Clark-Lewis, I.2    Zwahlen, R.3    Baggiolini, M.4
  • 7
    • 9444267059 scopus 로고    scopus 로고
    • The CXC chemokines growth-regulated oncogene (GRO) α, GROβ, GROγ, neutrophil-activating peptide-2, and epithelial cell-derived neutrophil-activating peptide-78 are potent agonists for the type B, hut not the type A, human interleukin-8 receptor
    • Ahuja, S. K., and Murphy, P. M. The CXC chemokines growth-regulated oncogene (GRO) α, GROβ, GROγ, neutrophil-activating peptide-2, and epithelial cell-derived neutrophil-activating peptide-78 are potent agonists for the type B, hut not the type A, human interleukin-8 receptor. J. Biol. Chem., 271: 20545-20550, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 20545-20550
    • Ahuja, S.K.1    Murphy, P.M.2
  • 8
    • 0026453101 scopus 로고
    • Cytokine dysregulation in AIDS: In vivo overexpression of mRNA of tumor necrosis factor-α and its correlation with that of the inflammatory cytokine GRO
    • Dezube, B. J., Pardee, A. B., Beckett, L. A., Ahlers, C. M., Ecto, L., Allen-Ryan, J., Anisowicz, A., Sager, R., and Crumpacker, C. S. Cytokine dysregulation in AIDS: in vivo overexpression of mRNA of tumor necrosis factor-α and its correlation with that of the inflammatory cytokine GRO. J. AIDS. 5: 1099-1104, 1992.
    • (1992) J. AIDS , vol.5 , pp. 1099-1104
    • Dezube, B.J.1    Pardee, A.B.2    Beckett, L.A.3    Ahlers, C.M.4    Ecto, L.5    Allen-Ryan, J.6    Anisowicz, A.7    Sager, R.8    Crumpacker, C.S.9
  • 9
    • 0028093436 scopus 로고
    • Expression of the chemokine superfamily in rheumatoid arthritis
    • Hosaka, S., Akahoshi, T., Wada, C., and Kondo, H. Expression of the chemokine superfamily in rheumatoid arthritis. Clin. Exp. Immunol., 97: 451-457, 1994.
    • (1994) Clin. Exp. Immunol. , vol.97 , pp. 451-457
    • Hosaka, S.1    Akahoshi, T.2    Wada, C.3    Kondo, H.4
  • 10
    • 0031802994 scopus 로고    scopus 로고
    • Hemorrhagic shock primes for increased expression of cytokine-induced neutrophil chemoattractant in the lung: Role in pulmonary inflammation following lipopolysaccharide
    • Fan, J., Marshall, J. C., Jimenez, M., Shek, P. N., Zagorski, J., and Rotstein, O. D. Hemorrhagic shock primes for increased expression of cytokine-induced neutrophil chemoattractant in the lung: role in pulmonary inflammation following lipopolysaccharide. J. Immunol., 161: 440-447, 1998.
    • (1998) J. Immunol. , vol.161 , pp. 440-447
    • Fan, J.1    Marshall, J.C.2    Jimenez, M.3    Shek, P.N.4    Zagorski, J.5    Rotstein, O.D.6
  • 11
    • 0030741003 scopus 로고    scopus 로고
    • Role of cytokine-induced neutrophil chemoattractant (CINC) in ozone-induced airway inflammation and hyperresponsiveness
    • Koto, H., Salmon, M., Haddad, el-B., Huang, T. J., Zagorski, J., and Chung, K. F. Role of cytokine-induced neutrophil chemoattractant (CINC) in ozone-induced airway inflammation and hyperresponsiveness. Am. J. Respir. Crit. Care Med., 156: 234-239, 1997.
    • (1997) Am. J. Respir. Crit. Care Med. , vol.156 , pp. 234-239
    • Koto, H.1    Salmon, M.2    Haddad, E.-B.3    Huang, T.J.4    Zagorski, J.5    Chung, K.F.6
  • 12
    • 0030747827 scopus 로고    scopus 로고
    • Enhanced degradation of I-κB a contributes to endogenous activation of NF-κB in Hs294T melanoma cells
    • Shattuck-Brandt, R. L., and Richmond, A. Enhanced degradation of I-κB a contributes to endogenous activation of NF-κB in Hs294T melanoma cells. Cancer Res., 57: 3032-3039, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 3032-3039
    • Shattuck-Brandt, R.L.1    Richmond, A.2
  • 13
    • 0025828347 scopus 로고
    • Constitutive expression of multiple growth factor genes by melanoma cells but not normal melanocytes
    • Rodeck, U., Melber, K., Kath, R., Menssen, H. D., Varello, M., Atkinson, B., and Herlyn, M. Constitutive expression of multiple growth factor genes by melanoma cells but not normal melanocytes. J. Invest. Dermatol., 97: 20-26, 1991.
    • (1991) J. Invest. Dermatol. , vol.97 , pp. 20-26
    • Rodeck, U.1    Melber, K.2    Kath, R.3    Menssen, H.D.4    Varello, M.5    Atkinson, B.6    Herlyn, M.7
  • 14
    • 0028324596 scopus 로고
    • Expression of cytokine/growth factors and their receptors in human melanoma and melanocytes
    • Mattei, S., Colombo, M. P., Melani, C., Silvani, A., Parmiani, G., and Herlyn, M. Expression of cytokine/growth factors and their receptors in human melanoma and melanocytes. Int. J. Cancer. 56: 853-857, 1994.
    • (1994) Int. J. Cancer. , vol.56 , pp. 853-857
    • Mattei, S.1    Colombo, M.P.2    Melani, C.3    Silvani, A.4    Parmiani, G.5    Herlyn, M.6
  • 16
    • 0029557908 scopus 로고
    • Constitutive and cytokine-induced expression of the melanoma growth stimulatory activity/GRO α gene requires both NF-κB and novel constitutive factors
    • Wood, L. D., and Richmond, A. Constitutive and cytokine-induced expression of the melanoma growth stimulatory activity/GRO α gene requires both NF-κB and novel constitutive factors. J. Biol. Chem., 270: 30619-30626, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 30619-30626
    • Wood, L.D.1    Richmond, A.2
  • 17
    • 0028783404 scopus 로고
    • HMGI(Y), and Spl in addition to NF-κB regulate transcription of the MGSA/GRO α gene
    • Wood, L. D., Farmer, A. A., and Richmond. A. HMGI(Y), and Spl in addition to NF-κB regulate transcription of the MGSA/GRO α gene. Nucleic Acids Res., 23: 4210-4219, 1995.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 4210-4219
    • Wood, L.D.1    Farmer, A.A.2    Richmond, A.3
  • 18
    • 0028971289 scopus 로고
    • Rel/NF-κ B/I κ B family: Intimate tales of association and dissociation
    • Verma, I. M., Stevenson, J. K., Schwarz, E. M., Van Antwerp, D., and Miyamolo, S. Rel/NF-κ B/I κ B family: intimate tales of association and dissociation. Genes Dev., 9: 2723-2735, 1995.
    • (1995) Genes Dev. , vol.9 , pp. 2723-2735
    • Verma, I.M.1    Stevenson, J.K.2    Schwarz, E.M.3    Van Antwerp, D.4    Miyamolo, S.5
  • 19
    • 0031897632 scopus 로고    scopus 로고
    • NF-κ B and Rel proteins: Evolutionarily conserved mediators of immune responses
    • Ghosh, S., May, M. J., and Kopp, E. B. NF-κ B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol., 16: 225-260, 1998.
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 225-260
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 20
    • 0031586174 scopus 로고    scopus 로고
    • Identification and characterization of an IκB kinase
    • Regnier, C. H . Song, H. Y., Gao, X., Goeddel, D. V., Cao, Z., and Rothe, M. Identification and characterization of an IκB kinase. Cell, 90: 373-383, 1997.
    • (1997) Cell , vol.90 , pp. 373-383
    • Regnier, C.H.1    Song, H.Y.2    Gao, X.3    Goeddel, D.V.4    Cao, Z.5    Rothe, M.6
  • 22
    • 0030613551 scopus 로고    scopus 로고
    • The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation
    • Zandi, E., Rothwarf, D. M., Delhase, M., Hayakawa, M., and Karin, M. The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation. Cell, 91: 243-252, 1997.
    • (1997) Cell , vol.91 , pp. 243-252
    • Zandi, E.1    Rothwarf, D.M.2    Delhase, M.3    Hayakawa, M.4    Karin, M.5
  • 23
    • 0030611595 scopus 로고    scopus 로고
    • IκB kinase-β. NF-κB activation and complex formation with IκB kinase-αand NIK
    • Woronicz, J. D., Gao, X., Cao, Z., Rothe, M., and Goeddel, D. V. IκB kinase-β. NF-κB activation and complex formation with IκB kinase-αand NIK. Science (Washington, DC), 278: 866-869, 1997.
    • (1997) Science (Washington, DC) , vol.278 , pp. 866-869
    • Woronicz, J.D.1    Gao, X.2    Cao, Z.3    Rothe, M.4    Goeddel, D.V.5
  • 24
    • 0032575379 scopus 로고    scopus 로고
    • Direct phosphorylation of IκB by IKKα and IKKβ: Discrimination between free and NF-κB-bound substrate
    • Zandi, E., Chen, Y., and Karin, M. Direct phosphorylation of IκB by IKKα and IKKβ: discrimination between free and NF-κB-bound substrate. Science (Washington, DC), 281: 1360-1363, 1998.
    • (1998) Science (Washington, DC) , vol.281 , pp. 1360-1363
    • Zandi, E.1    Chen, Y.2    Karin, M.3
  • 25
    • 0030610362 scopus 로고    scopus 로고
    • A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
    • DiDonato, J. A., Hayakawa, M., Rothwarf, D. M., Zandi, E., and Karin M. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB. Nature (Lond.), 388: 548-554, 1997.
    • (1997) Nature (Lond.) , pp. 548-554
    • DiDonato, J.A.1    Hayakawa, M.2    Rothwarf, D.M.3    Zandi, E.4    Karin, M.5
  • 26
    • 0032583947 scopus 로고    scopus 로고
    • NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176
    • Ling, L., Cao, Z., and Goeddel, D. V. NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176. Proc. Natl. Acad. Sci. USA, 95: 3792-3797, 1998.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 3792-3797
    • Ling, L.1    Cao, Z.2    Goeddel, D.V.3
  • 27
    • 0032577708 scopus 로고    scopus 로고
    • Constitutive activation of NF-κB causes resistance to apoptosis in human cutaneous T cell lymphoma HuT-78 cells. Autocrine role of tumor necrosis factor and reactive oxygen intermediates
    • Giri, D. K., and Aggarwal, B. B. Constitutive activation of NF-κB causes resistance to apoptosis in human cutaneous T cell lymphoma HuT-78 cells. Autocrine role of tumor necrosis factor and reactive oxygen intermediates. J. Biol. Chem., 273: 14008-14014, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 14008-14014
    • Giri, D.K.1    Aggarwal, B.B.2
  • 28
    • 0030927167 scopus 로고    scopus 로고
    • Constitutive activation of NF-κB during progression of breast cancer to hormone-independent growth
    • Nakshatri, H., Bhat-Nakshatri, P., Martin, D. A., Goulet. R. J., Jr., and Sledge, G. W., Jr. Constitutive activation of NF-κB during progression of breast cancer to hormone-independent growth. Mol. Cell. Biol., 17: 3629-3639, 1997.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 3629-3639
    • Nakshatri, H.1    Bhat-Nakshatri, P.2    Martin, D.A.3    Goulet R.J., Jr.4    Sledge G.W., Jr.5
  • 29
    • 0032568816 scopus 로고    scopus 로고
    • The tax oncoprotein of human T-cell leukemia virus type I associates with and persistently activates IκB kinases containing IKKα and IKKβ
    • Chu, Z. L., DiDonato, I. A., Hawiger, J., and Ballard, D. W. The tax oncoprotein of human T-cell leukemia virus type I associates with and persistently activates IκB kinases containing IKKα and IKKβ. J. Biol. Chem., 273: 15891-15894, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 15891-15894
    • Chu, Z.L.1    DiDonato, I.A.2    Hawiger, J.3    Ballard, D.W.4
  • 31
    • 0030885421 scopus 로고    scopus 로고
    • Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-κB control
    • Chu, Z. L., McKinsey, T. A., Liu, L. Gentry, J. J., Malim, M. H., and Ballard, D. W. Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-κB control. Proc. Natl. Acad. Sci. USA. 94: 10057-10062, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10057-10062
    • Chu, Z.L.1    McKinsey, T.A.2    Liu, L.3    Gentry, J.J.4    Malim, M.H.5    Ballard, D.W.6
  • 32
    • 0031596337 scopus 로고    scopus 로고
    • NF-κB-mediated inhibition of apoptosis is required for encephalomyocarditis virus virulence: A mechanism of resistance in p50 knockout mice
    • Schwarz, E. M., Badorff, C., Hiura, T. S., Wessely, R., Badorff, A., Verma, I. M., and Knowlton, K. U. NF-κB-mediated inhibition of apoptosis is required for encephalomyocarditis virus virulence: a mechanism of resistance in p50 knockout mice. J. Virol., 72: 5654-5660, 1998.
    • (1998) J. Virol. , vol.72 , pp. 5654-5660
    • Schwarz, E.M.1    Badorff, C.2    Hiura, T.S.3    Wessely, R.4    Badorff, A.5    Verma, I.M.6    Knowlton, K.U.7
  • 33
    • 0029858387 scopus 로고    scopus 로고
    • TNF-and cancer therapy-induced apoplosis: Potentiation by inhibition of NF-κB
    • Wang, C.-Y., Mayo, M. W., and Baldwin, A. S., Jr. TNF-and cancer therapy-induced apoplosis: potentiation by inhibition of NF-κB. Science (Washington, DC), 274: 784-787, 1996.
    • (1996) Science (Washington, DC) , vol.274 , pp. 784-787
    • Wang, C.-Y.1    Mayo, M.W.2    Baldwin A.S., Jr.3
  • 35
    • 0028137830 scopus 로고
    • MGSA/GRO transcription is differentially regulated in normal retinal pigment epithelial and melanoma cells
    • Shattuck, R. L., Wood, L. D., Jaffe, G. J., and Richmond, A. MGSA/GRO transcription is differentially regulated in normal retinal pigment epithelial and melanoma cells. Mol. Cell. Biol., 14: 791-802, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 791-802
    • Shattuck, R.L.1    Wood, L.D.2    Jaffe, G.J.3    Richmond, A.4
  • 37
    • 0030925372 scopus 로고    scopus 로고
    • Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-κB
    • Boothby, M. R., Mora, A. L., Scherer, D C., Brockman, J. A., and Ballard, D. W. Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-κB. J. Exp. Med., 185: 1897-1907, 1997.
    • (1997) J. Exp. Med. , vol.185 , pp. 1897-1907
    • Boothby, M.R.1    Mora, A.L.2    Scherer, D.C.3    Brockman, J.A.4    Ballard, D.W.5
  • 38
    • 0015847039 scopus 로고
    • A new technique for the assay of infectivity of human adenovirus 5 DNA
    • Graham, F. L., and van der Eb, A. J. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology, 52: 456-467, 1973.
    • (1973) Virology , vol.52 , pp. 456-467
    • Graham, F.L.1    Van Der Eb, A.J.2
  • 40
    • 0029146930 scopus 로고
    • Signal-induced site-specific phosphorylalion targets IκBα to the ubiquitin-proteasome pathway
    • Chen, Z . Hagler, J., Palombella, V. J., Melandri, F., Scherer, D., Ballard, D., and Maniatis, T. Signal-induced site-specific phosphorylalion targets IκBα to the ubiquitin-proteasome pathway. Genes Dev., 9: 1586-1597, 1995.
    • (1995) Genes Dev. , vol.9 , pp. 1586-1597
    • Chen, Z.1    Hagler, J.2    Palombella, V.J.3    Melandri, F.4    Scherer, D.5    Ballard, D.6    Maniatis, T.7
  • 41
    • 0030772376 scopus 로고    scopus 로고
    • Novel inhibitors of cytokine-induced IκBα phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo
    • Pierce, J. W., Schoenleber, R., Jesmok, G., Best, J., Moore, S. A., Collins, T., and Gerrilscn, M. E. Novel inhibitors of cytokine-induced IκBα phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. J. Biol. Chem., 272: 21096-21103, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 21096-21103
    • Pierce, J.W.1    Schoenleber, R.2    Jesmok, G.3    Best, J.4    Moore, S.A.5    Collins, T.6    Gerrilscn, M.E.7
  • 42
    • 0028979596 scopus 로고
    • Activation of NF-κB/Rel by Tax involves degradation of IκBα and is blocked by a proteasome inhibitor
    • Maggirwar, S. B., Harhaj, E., and Sun, S. C. Activation of NF-κB/Rel by Tax involves degradation of IκBα and is blocked by a proteasome inhibitor. Oncogene, 11: 993-998, 1995.
    • (1995) Oncogene , vol.11 , pp. 993-998
    • Maggirwar, S.B.1    Harhaj, E.2    Sun, S.C.3
  • 43
    • 0028978032 scopus 로고
    • Phosphorylation of human IκB-α on serines 32 and 36 controls IκB-α proteolysis and NF-κB activation in response to diverse stimuli
    • Traenckner, E. B., Pahl, H. L., Henkel, T., Schmidt, K. N., Wilk, S., and Baeuerle PA. Phosphorylation of human IκB-α on serines 32 and 36 controls IκB-α proteolysis and NF-κB activation in response to diverse stimuli. EMBO J., 14: 2876-2883, 1995.
    • (1995) EMBO J. , vol.14 , pp. 2876-2883
    • Traenckner, E.B.1    Pahl, H.L.2    Henkel, T.3    Schmidt, K.N.4    Wilk, S.5    Baeuerle, P.A.6
  • 44
    • 0030004897 scopus 로고    scopus 로고
    • Site-specific phosphorylation of IκBα by a novel ubiquitination-dependent protein kinase activity
    • Chen, Z., J., Parent, L., and Maniatis T. Site-specific phosphorylation of IκBα by a novel ubiquitination-dependent protein kinase activity. Cell. 84: 853-862, 1996.
    • (1996) Cell , vol.84 , pp. 853-862
    • Chen, Z.J.1    Parent, L.2    Maniatis, T.3
  • 45
    • 0026737784 scopus 로고
    • The Rel family: Models for transcriptional regulation and oncogenic transformation
    • Bose, H. R., Jr. The Rel family: models for transcriptional regulation and oncogenic transformation. Biochim. Biophys. Acta, 1114: 1-17, 1992.
    • (1992) Biochim. Biophys. Acta , vol.1114 , pp. 1-17
    • Bose H.R., Jr.1
  • 46
    • 0025689450 scopus 로고
    • The rel gene and its role in oncogenesis
    • Enrietto, P. J. The rel gene and its role in oncogenesis. Semin. Cancer Biol., 1: 399-405, 1990.
    • (1990) Semin. Cancer Biol. , vol.1 , pp. 399-405
    • Enrietto, P.J.1
  • 47
    • 0025835619 scopus 로고
    • Malignant transformation by mutant Rel proteins
    • Gilmore, T. D. Malignant transformation by mutant Rel proteins. Trends Genet., 7: 318-322, 1991.
    • (1991) Trends Genet. , vol.7 , pp. 318-322
    • Gilmore, T.D.1
  • 48
    • 0026472154 scopus 로고
    • Role of rel family genes in normal and malignant lymphoid cell growth
    • Gilmore, T. D. Role of rel family genes in normal and malignant lymphoid cell growth. Cancer Surv., 15: 69-87, 1992.
    • (1992) Cancer Surv. , vol.15 , pp. 69-87
    • Gilmore, T.D.1
  • 50
    • 0031982710 scopus 로고    scopus 로고
    • Discrimination between RelA and RelB transcriptional regulation by a dominant negative mutant of IκBα
    • Ferreira, V., Tarantino, N., and Korner, M. Discrimination between RelA and RelB transcriptional regulation by a dominant negative mutant of IκBα. J. Biol. Chem., 273: 592-599, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 592-599
    • Ferreira, V.1    Tarantino, N.2    Korner, M.3
  • 51
    • 0032516520 scopus 로고    scopus 로고
    • NF-κB-inducing kinase and IκB kinase participate in human T-cell leukemia virus I tax-mediated NF-κB activation
    • Uhlik, M., Good, L., Xiao, G., Harhaj, E. W., Zandi, E., Karin, M., and Sun, S. C. NF-κB-inducing kinase and IκB kinase participate in human T-cell leukemia virus I tax-mediated NF-κB activation. J. Biol. Chem., 273: 21132-21136, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 21132-21136
    • Uhlik, M.1    Good, L.2    Xiao, G.3    Harhaj, E.W.4    Zandi, E.5    Karin, M.6    Sun, S.C.7
  • 52
  • 54
    • 0028104173 scopus 로고
    • Molecular structure and organization of the human manganese superoxide dismutase gene
    • Wan, X. S., Devalaraja, M. N., and St. Clair, D. K. Molecular structure and organization of the human manganese superoxide dismutase gene. DNA Cell Biol., 13: 1127-1136, 1994
    • (1994) DNA Cell Biol. , vol.13 , pp. 1127-1136
    • Wan, X.S.1    Devalaraja, M.N.2    St. Clair, D.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.