A GPI-linked protein that interacts with ret to form a candidate neurturin receptor

Nature

Volumn 387, Issue 6634, 1997, Pages 717-721

  Klein, Robert D ^a,b   Sherman, Daniel ^a   Ho, Wei Hsien ^a   Stone, Donna ^a   Bennett, Gregory L ^a   Moffat, Barbara ^a   Vandlen, Richard ^a   Simmons, Laura ^a,d   Gu, Qimin ^a,d   Hongo, Jo Anne ^a   Devaux, Brigitte ^a   Poulsen, Kris ^a   Armanini, Mark ^a   Nozaki, Chika ^b   Asai, Naoya ^b   Goddard, Audrey ^a,d   Phillips, Heidi ^a   Henderson, Chris E ^c   Takahashi, Masahide ^b   Rosenthal, Arnon ^a  

^a GENENTECH INC   (United States)

^b NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c AIX MARSEILLE UNIVERSITÉ   (France)

^d Deltagen Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYPICAN;

ARTICLE; CENTRAL NERVOUS SYSTEM; GLIA CELL; GLYCOSYLATION; LIGAND BINDING; OUTER MEMBRANE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; ANIMALS; BINDING, COMPETITIVE; CELL MEMBRANE; CELL SURVIVAL; DROSOPHILA PROTEINS; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTORS; GLYCOSYLPHOSPHATIDYLINOSITOLS; HUMANS; IN SITU HYBRIDIZATION; LIGANDS; MICE; MOLECULAR SEQUENCE DATA; MOTOR NEURONS; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEURONS; NEURTURIN; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-RET; RATS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, CELL SURFACE; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION;

EID: 16944365682     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/42722     Document Type: Article

References (28)

1. Lin, L. H., Doherty, D. H., Lile, J. D., Bcktesh, S. & Collins, F. GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260, 1130-1132 (1993).
2. Kotzbaucr, P. T. et al. Neurturin, a relative of glial-cell-line-derived neurotrophic factor. Nature 384, 467-470 (1996).
3. Henderson, C. E. et al. GDNF: A potent survival factor for motoneurons present in peripheral nerve and muscle. Science 266, 1062-1064 (1994).
4. Buj-Bell, A., Buchman, V. L., Ilorton, A., Rosenthal, A. & Davies, A. M. GDNF is an age-specific survival factor for sensory and autonomic neurons. Neuron 15, 821-828 (1995).
5. Arenas, E., Trupp, M., Akerud, P. & Ibáñiez, C. F. GDNF prevents degeneration and promotes the phenotype of brain noradrenergic neurons in vivo. Neuron 15, 1465-1473 (1995).
6. Trupp, M. et al. Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons. J. Cell Biol. 130, 137-148 (1995).
7. Takahashi, M., Ritz, J. & Cooper, G. M. Activation of a novel human transforming gene, ret, by DNA rearrangement. Cell 42, 581-588 (1985).
8. Takahashi, M. & Cooper, G. M. ret Transforming gene encodes a fusion protein homologous to tyrosine kinases. Mot. Cell Biol. 7, 1378-1385 (1987).
9. Treanor, J. J. S. et al. Characterization of a multicomponent receptor for GDNF. Nature 382, 80-83 (1996).
10. Jing, S. et al. GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-α, a novel receptor for GDNT. Cell 85, 1113-1124 (1996).
11. Trupp, M. et al. Functional receptor for GDNF encoded by the c-ret proto-oncogene. Nature 381, 785-789 (1996).
12. Durbec, P. et al. GDNF signalling through the Ret receptor tyrosine kinase. Nature 381, 789-793 (1996).
13. Koke, J. A., Yang, M., Henner, D. J., Volwerk, J. J. & Griffith, O. H. High-level expression in Escherichia coli and rapid purification of phosphatidylinositol-specific phospholipase C from Bacillus cereus and Bacillus thuringiensis. Protein Expr. Purif. 2, 51-58 (1991).
14. Ikeda, I. et al. Specific expression of the ret proto-oncogene in human neuroblastoma cell lines. Oncogene 5, 1291-1296 (1990).
15. Takahashi, M., Buma, Y. & Taniguchi, M. Identification of the ret proto-oncogene products in neuroblastoma and leukemia cells. Oncogene 6, 297-301 (1991).
16. Davis, S. et al. Released form of CNTF receptor a component as a soluble mediator of CNTF responses. Science 259, 1736-1739 (1993).
17. Schuchardt, A., D'Agati, V., Larsson-Blomberg, L, Costantini, F. & Pachnis, V. Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret Nature 367, 380-383 (1996).
18. Durbec, P. L., Larsson-Blomberg, L. B., Schuchardt, A., Costantini, F. & Pachnis, V. Development 122, 349-358 (1996).
19. Pichel, J. G. et al. Defects in enteric innervation and kidney development in mice lacking GDN'F. Nature 382, 73-76 (1996).
20. Sinchez, M. P. et al. Renal agenesis and the absence of enteric neurons in mice lacking GDNE Nature 382, 70-73 (1996).
21. Moore, M. W. et al. Renal and neuronal abnormalities in mice lacking GDNF. Nature 382, 76-79 (1996).
22. Lindsay, R. M. & Yancopoulos, G. D. GDN'F in a bind with known orphan: Accessory implicated in new twist. Neuron 17, 571-574 (1996).
23. Ip, N. Y. et al. CNTF and LIF action neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp 130. Cell 69, 1121-1132 (1992).
24. Wrana, J. L., Attisano, L., Weser, R., Ventura, F. & Massague, J. Mechanism of activation of the TGF-β receptor. Nature 370, 341-347 (1994).
25. Lee, J.-D. et al. Glycosyl-phosphatidylinositol-anchored or integral membrane forms of CD14 mediate identical cellular responses to endotoxin. Proc. Natl Acad. Sci. USA 90, 9930-9934 (1993).
26. Pugin, J. et al. Lipopolysaccharide (LPS) activation of human endothelial and epithelial cells is mediated by LPS binding protein and soluble CD14. Proc. Natl Acad. Sci. USA 90, 2744-2748 (1993).
27. Hochuli, E., Dobeli, H. & Schacher, A. New metal chelate adsorbent selective for proteins and peptides containing neighboring histidine residues. J. Chromatogr. 411, 177-184 (1987).
28. Henderson, C. E. et al. in Nerve Cell Culture: A Practical Approach (eds Cohen, J. & Wilkin, G.) 69-81 (Oxford Univ. Press, 1995).