A genetic screen to identify components of the sina signaling pathway in Drosophila eye development

Genetics

Volumn 148, Issue 1, 1998, Pages 277-286

  Neufeld, Thomas P ^a,b   Tang, Amy H ^a   Rubin, Gerald M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

UBIQUITIN; UBIQUITIN CONJUGATING ENZYME;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; DROSOPHILA; ENHANCER REGION; EYE DEVELOPMENT; FEMALE; GENETIC SCREENING; MALE; MOLECULAR CLONING; MOLECULAR GENETICS; NONHUMAN; PHENOTYPE; PHOTORECEPTOR CELL; PRIORITY JOURNAL; REPRESSOR GENE; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; DROSOPHILA; ENHANCER ELEMENTS (GENETICS); EYE; EYE ABNORMALITIES; GENES, SUPPRESSOR; INSECT PROTEINS; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PHENOTYPE; REPRESSOR PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES;

EID: 0031882496     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. AYER, D. E., Q. A. LAWRENCE and R. N. EISENMAN, 1995 Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3. Cell 80: 767-776.
2. BOHMANN, D., M. C. ELLIS, L. M. STASZEWSKI and M. MLODZIK 1994 Drosophila Jun mediates Ras-dependent photoreceptor determination. Cell 78: 973-986.
3. CARTHEW, R. W., and G. M. RUBIN, 1990 seven in absentia, a gene required for specification of R7 cell fate in the Drosophilla eye. Cell 63: 561-577.
4. CATHEW, R. W., T. P. NEUFELD and G. M. RUBIN, 1994 Identification of genes that interact with the sina gene in Drosophila eye development. Proc. Natl. Acad. Sci. USA 91: 11689-11693.
5. CENCI, G., R. B. RAWSON, G. BELLONI, D. H. CASTRILLON, M. TUDOR et al., 1997 UbcD1, a Drosophila ubiquitin-conjugating enzyme required for proper telomere behavior. Genes Dev. 11: 863-875.
6. CHANG, H. C., N. M. SOLOMON, D. A. WASSERMAN, F. D. KARIM, M. THERRIEN et al., 1994 phyllopod functions downstream of Ras1 in the fate determination of a subset of photoreceptions in Drosophila. Cell 80: 463-472.
7. COUCH, F. J., J. M. ROMMENS, S. L. NEUHAUSEN, C. BELANGER, M. DUMONT et al., 1996 Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13. Genomics 36: 86-99.
8. CUTFORTH, T. L., 1994 Genetic and molecular dissection of signaling by the sevenless receptor in Drosophila melanogaster. Ph.D. Thesis, University of California, Berkeley.
9. FISCHER-VIZE, J. A., and K. L. MOSLEY, 1994 Marbles mutants: uncoupling cell determination and nuclear migration in the developing Drosophila eye. Development 120: 2609-2618.
10. FORTINI, M. E., M. A. SIMON and G. M. RUBIN, 1992 Signaling by the sevenless protein tyrosine kinase is mimicked by Ras1 activation. Nature 355: 559-561.
11. HAY, B. A., T. WOLFF and G. M. RUBIN, 1994 Expression of baculovirus P35 prevents cell death in Drosophila. Development 120: 2121-2129.
12. HEBERLEIN, U., and G. M. RUBIN, 1991 Star is required in a subset of photoreceptor cells in the developing Drosophila retina and displays dosage sensitive interactions with rough. Dev. Biol. 144: 353-361.
13. HU, G., S. ZHANG, M. VIDAL, J. BER, T. XU et al., 1997 Mammalian homologs of sina (seven in absentia) regulate DCC via the ubiquitin-proteasome pathway. Genes Dev. 11: 2701-2714.
14. HUANG, Y., R. T. BAKER and J. A. FISCHER-VIZE, 1995 Control of cell fate by a deubiquitinating enzyme encoded by the fat facets gene. Science 270: 1828-1831.
15. KARIM, F. D., H. C. CHANG, M. THERRIEN, D. A. WASSERMAN, T. LAVERTY et al., 1996 A screen for genes that functions downstream of Ras1 during Drosophila eye development. Genetics 143: 315-329.
16. KAUFMANN, R. C., S. LI, P. A. GALLAGHER and R. W. CARTHEW, 1996 Ras1 signaling and transcriptional competence in the R7 cell of Drosophila. Genes Dev. 10: 2167-2178.
17. KRAMER, H., R. L. CAGAN and S. L. ZIPURSKY, 1991 Interaction of bride of sevenless membrane-bound ligand and the sevenless tyrosine-kinase receptor. Nature 352: 207-212.
18. KOLODKIN, A. L., A. T. PICKUP, D. R. LIN, C. S. GOODMAN and U. BANERJEE, 1994 Characterization of Star and its interactions with sevenless and EGF receptor during photoreceptor cell development in Drosophila. Development 120: 1731-1745.
19. LAHERTY, C. D., W.-M. YANG, J.-M. SUN, J. R. DAVIE, E. SETO et al., 1997 Histone deacetylases associated with the mSin3 corepressor mediate Mad transcriptional repression. Cell 89: 349-356.
20. LAI, Z.-C., S. D. HARRISON, F. KARIM, Y. LI and G. M. RUBIN, 1996 Loss of tramtrack gene activity results in ectopic R7 cell formation, even in a sina mutant background. Proc. Natl. Acad. Sci. USA 93: 5025-5030.
21. LEWIS, E. B., and F. BACHER, 1968 Method of feeding ethyl methanesulphonate to Drosophila males. Dros. Inf. Serv. 43: 193-194.
22. LI, S., Y. LI, R. W. CARTHEW and Z.-C. LAI, 1997 Photoreceptor cell differentiation requires regulated proteolysis of the transcriptional repressor Tramtrack. Cell 90: 469-478.
23. MOSES, K., M. C. ELLIS and G. M. RUBIN, 1989 The glass gene encodes a zinc-finger protein required by Drosophila photoreceptor cells. Nature 340: 531-536.
24. O'NEILL , E. M., I. REBAY, R. TJIAN and G. M. RUBIN, 1994 The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway. Cell 78: 137-147.
25. PIROTTA, V. 1986 Cloning Drosophila genes, pp. 83-110 in Drosophila: A Practical Approach, edited by D. R. ROBERTS. IRL, Washington, DC.
26. REBAY, I., and G. M. RUBIN, 1995 Yan functions as a general inhibitor of differentiation and is negatively regulated by activation of the Ras1/MAPK pathway. Cell 81: 857-866.
27. REINKE, R., and S. L. ZIPURSKY, 1988 Cell-cell interaction in the Drosophila retina: The bride of sevenless gene is required in photoreceptor cell R8 for R7 development. Cell 55: 321-330.
28. ROBINOW, S., and K. WHITE, 1991 Characterization and spatial distribution of the ELAV protein during Drosophila melanogaster development. J. Neurobiol. 22: 443-461.
29. SIMON, M. A., 1994 Signal transduction during the development of the Drosophila R7 photoreceptor. Dev. Biol. 166: 431-442.
30. SIMON, M. A., D. D. L. BOWTELL, G. S. DODSON, T. R. LAVERTY and G. M. RUBIN, 1991 Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase. Cell 67: 701-716.
31. SPRADLING, A. C., D. M. STERN, I. Kiss, J. ROOTE, T. LAVERTY et al., 1995 Gene disruptions using P transposable elements: an integral component of the Drosophila genome project. Proc. Natl. Acad. Sci. USA 92: 10824-10830.
32. 88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism. Cell 90: 459-467.
33. TOMLINSON, A., and D. F. READY, 1986 Sevenless: a cell specific homeotic mutation of the Drosophila eye. Science 231: 400-402.
34. TREIER, M., W. SEUFERT and S. JENTSCH, 1992 Drosophila UbcD1 encodes a highly conserved ubiquitin-conjugating enzyme involved in selective protein degradation. EMBO J. 11: 367-372.
35. VAN VACTOR, D. L., JR., R. L. CAGAN, H. KRAMER and S. L. ZIPURSKY, 1991 Induction in the developing compound eye of Drosophila: Multiple mechanisms restrict R7 induction to a single retinal precursor cell. Cell 67: 1145-1155.
36. WANG, H., I. CLARK, P. R. NICHOLSON, I. HERSKOWITZ and D. J. STILLMAN, 1990 The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs. Mol. Cell. Biol. 10: 5927-5936.
37. WASSERMAN, D. A., M. THERRIEN and G. M. RUBIN, 1995 The Ras signaling pathway in Drosophila. Curr. Opin. Genet. Dev. 5: 44-50.
38. XU, T., and G. M. RUBIN, 1993 Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 117: 1223-1237.
39. ZIPURSKY, S. L., and G. M. RUBIN, 1994 Determination of neuronal cell fate: lessons from the R7 neuron of Drosophila. Annu. Rev. Neurosci. 17: 373-397.