Multiple endocrine neoplasia type 2B mutation in human RET oncogene induces medullary thyroid carcinoma in transgenic mice

Oncogene

Volumn 19, Issue 27, 2000, Pages 3121-3125

  Acton, Dennis S ^a   Velthuyzen, Danny ^a   Lips, Cornelis J M ^a   Höppener, Jo W M ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Human RET transgenic mice; Medullary thyroid carcinoma; Multiple endocrine neoplasia type 2B

Indexed keywords

CALCITONIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER SUSCEPTIBILITY; CELL HYPERPLASIA; CONTROLLED STUDY; FEMALE; GENETIC PREDISPOSITION; MALE; MOUSE; MULTIPLE ENDOCRINE NEOPLASIA; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTO ONCOGENE; THYROID CARCINOMA; THYROID PARAFOLLICULAR CELL; TRANSGENIC MOUSE;

EID: 0034702207     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1203648     Document Type: Article

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