-
1
-
-
1642395858
-
Antibody humanization by CDR grafting
-
LO BK: Antibody humanization by CDR grafting. Methods Mol. Biol. (2004) 248:135-159.
-
(2004)
Methods Mol. Biol.
, vol.248
, pp. 135-159
-
-
Lo, B.K.1
-
2
-
-
1842368507
-
IDEC-C2B8 (Rituximab) Anti-CD20 Monoclonal Antibody Therapy in Patients With Relapsed Low-Grade Non-Hodgkin's Lymphoma
-
MALONEY DG, GRILLO-LOPEZ AJ, WHITE CA et al.: IDEC-C2B8 (Rituximab) Anti-CD20 Monoclonal Antibody Therapy in Patients With Relapsed Low-Grade Non-Hodgkin's Lymphoma. Blood (1997) 90:2188-2195.
-
(1997)
Blood
, vol.90
, pp. 2188-2195
-
-
Maloney, D.G.1
Grillo-Lopez, A.J.2
White, C.A.3
-
3
-
-
0242694519
-
HER-2-targeted therapy: Lessons learned and future directions
-
NAHTA R, ESTEVA FJ: HER-2-targeted therapy: lessons learned and future directions. Clin. Cancer Res. (2003) 9:5078-5084.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 5078-5084
-
-
Nahta, R.1
Esteva, F.J.2
-
4
-
-
0033883776
-
SU6668 Is a Potent Antiangiogenic and Antitumor Agent That Induces Regression of Established Tumors
-
LAIRD AD, VAJKOCZY P, SHAWVER LK et al.: SU6668 Is a Potent Antiangiogenic and Antitumor Agent That Induces Regression of Established Tumors. Cancer Res. (2000) 60:4152-4160.
-
(2000)
Cancer Res.
, vol.60
, pp. 4152-4160
-
-
Laird, A.D.1
Vajkoczy, P.2
Shawver, L.K.3
-
5
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
DRUKER BJ, TALPAZ M, RESTA DJ et al.: Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N. Engl. J. Med. (2001) 344:1031-1037.
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
-
6
-
-
0037109014
-
ZD1839 (Iressa): An Orally Active Inhibitor of Epidermal Growth Factor Signaling with Potential for Cancer Therapy
-
WAKELING AE, GUY SP, WOODBURN JR et al.: ZD1839 (Iressa): An Orally Active Inhibitor of Epidermal Growth Factor Signaling with Potential for Cancer Therapy. Cancer Res. (2002) 62:5749-5754.
-
(2002)
Cancer Res.
, vol.62
, pp. 5749-5754
-
-
Wakeling, A.E.1
Guy, S.P.2
Woodburn, J.R.3
-
7
-
-
3042577683
-
Approval summary for bortezomib for injection in the treatment of multiple myeloma
-
BROSS PF, KANE R, FARRELL AT et al.: Approval summary for bortezomib for injection in the treatment of multiple myeloma. Clin. Cancer Res. (2004) 10:3954-3964.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 3954-3964
-
-
Bross, P.F.1
Kane, R.2
Farrell, A.T.3
-
8
-
-
0036467826
-
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
-
VOGEL CL, COBLEIGH MA, TRIPATHY D et al.: Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J. Clin. Oncol. (2002) 20:719-726.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 719-726
-
-
Vogel, C.L.1
Cobleigh, M.A.2
Tripathy, D.3
-
9
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
PAEZ JG, JANNE PA, LEE JC et al.: EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science (2004) 304:1497-1500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
10
-
-
0001189211
-
Studies on prostatic cancer II. The effect of castration on clinical patients with carcinoma of the prostate
-
HUGGINS C, STEVENS RE, HODGES CL: Studies on prostatic cancer II. The effect of castration on clinical patients with carcinoma of the prostate. Arch. Surg. (1941) 43:209.
-
(1941)
Arch. Surg.
, vol.43
, pp. 209
-
-
Huggins, C.1
Stevens, R.E.2
Hodges, C.L.3
-
11
-
-
0034728828
-
Maximum androgen blockade in advanced prostate cancer: An overview of the randomised trials
-
PROSTATE CANCER TRIALISTS' COLLABORATIVE GROUP: Prostate Cancer Trialists' Collaborative Group
-
PROSTATE CANCER TRIALISTS' COLLABORATIVE GROUP: Maximum androgen blockade in advanced prostate cancer: an overview of the randomised trials. Prostate Cancer Trialists' Collaborative Group. Lancet (2000) 355:1491-1498.
-
(2000)
Lancet
, vol.355
, pp. 1491-1498
-
-
-
12
-
-
0037072063
-
Long-term results with immediate androgen suppression and external irradiation in patients with locally advanced prostate cancer (an EORTC study): A Phase III randomised trial
-
BOLLA M, COLLETTE L, BLANK L et al.: Long-term results with immediate androgen suppression and external irradiation in patients with locally advanced prostate cancer (an EORTC study): a Phase III randomised trial. Lancet (2002) 360:103-106.
-
(2002)
Lancet
, vol.360
, pp. 103-106
-
-
Bolla, M.1
Collette, L.2
Blank, L.3
-
13
-
-
0033540004
-
Immediate hormonal therapy compared with observation after radical prostatectomy and pelvic lymphadenectomy in men with node-positive prostate cancer
-
MESSING EM, MANOLA J, SAROSDY M et al.: Immediate hormonal therapy compared with observation after radical prostatectomy and pelvic lymphadenectomy in men with node-positive prostate cancer. N. Engl. J. Med. (1999) 341:1781-1788.
-
(1999)
N. Engl. J. Med.
, vol.341
, pp. 1781-1788
-
-
Messing, E.M.1
Manola, J.2
Sarosdy, M.3
-
14
-
-
0036645414
-
Molecular biology of the androgen receptor
-
GELMANN EP: Molecular biology of the androgen receptor. J. Clin. Oncol. (2002) 20:3001-3015.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 3001-3015
-
-
Gelmann, E.P.1
-
15
-
-
0036895169
-
Phase III study of mitoxantrone plus low dose prednisone versus low dose prednisone alone in patients with asymptomatic hormone refractory prostate cancer
-
BERRY W, DAKHIL S, MODIANO M, GREGURICH M, ASMAR L: Phase III study of mitoxantrone plus low dose prednisone versus low dose prednisone alone in patients with asymptomatic hormone refractory prostate cancer. J. Urol. (2002) 168:2439-2443.
-
(2002)
J. Urol.
, vol.168
, pp. 2439-2443
-
-
Berry, W.1
Dakhil, S.2
Modiano, M.3
Gregurich, M.4
Asmar, L.5
-
16
-
-
0032784113
-
Hydrocortisone with or without mitoxantrone in men with hormone-refractory prostate cancer: Results of the cancer and leukemia group B 9182 study
-
KANTOFF PW, HALABI S, CONAWAY M et al.: Hydrocortisone with or without mitoxantrone in men with hormone-refractory prostate cancer: results of the cancer and leukemia group B 9182 study. J. Clin. Oncol. (1999) 17:2506-2513.
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 2506-2513
-
-
Kantoff, P.W.1
Halabi, S.2
Conaway, M.3
-
17
-
-
0022552684
-
Regulation of testicular steroidogenesis by gonadotropin-releasing hormone agonists and antagonists
-
HUHTANIEMI I, NIKULA H, RANNIKKO S, CLAYTON R: Regulation of testicular steroidogenesis by gonadotropin-releasing hormone agonists and antagonists. J. Steroid Biochem. (1986) 24:169-176.
-
(1986)
J. Steroid Biochem.
, vol.24
, pp. 169-176
-
-
Huhtaniemi, I.1
Nikula, H.2
Rannikko, S.3
Clayton, R.4
-
18
-
-
6444243321
-
Abarelix: The first gonadotrophin-releasing hormone antagonist for the treatment of prostate cancer
-
MONGIAT-ARTUS P, TEILLAC P: Abarelix: the first gonadotrophin-releasing hormone antagonist for the treatment of prostate cancer. Expert Opin. Pharmacother. (2004) 5:2171-2179.
-
(2004)
Expert Opin. Pharmacother.
, vol.5
, pp. 2171-2179
-
-
Mongiat-Artus, P.1
Teillac, P.2
-
19
-
-
0032497522
-
Bilateral orchiectomy with or without flutamide for metastatic prostate cancer
-
EISENBERGER MA, BLUMENSTEIN BA, CRAWFORD ED et al.: Bilateral orchiectomy with or without flutamide for metastatic prostate cancer. N. Engl. J. Med. (1998) 339:1036-1042.
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 1036-1042
-
-
Eisenberger, M.A.1
Blumenstein, B.A.2
Crawford, E.D.3
-
20
-
-
2942584859
-
Intermittent Androgen Deprivation Therapy for Prostate Cancer
-
RASHID MH, CHAUDHARY UB: Intermittent Androgen Deprivation Therapy for Prostate Cancer. Oncologist (2004) 9:295-301.
-
(2004)
Oncologist
, vol.9
, pp. 295-301
-
-
Rashid, M.H.1
Chaudhary, U.B.2
-
21
-
-
1842612441
-
Molecular determinants of resistance to antiandrogen therapy
-
CHEN CD, WELSBIE DS, TRAN C et al.: Molecular determinants of resistance to antiandrogen therapy. Nat. Med. (2004) 10:33-39.
-
(2004)
Nat. Med.
, vol.10
, pp. 33-39
-
-
Chen, C.D.1
Welsbie, D.S.2
Tran, C.3
-
22
-
-
0028113415
-
Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor
-
CULIG Z, HOBISCH A, CRONAUER MV et al.: Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor. Cancer Res. (1994) 54:5474-5478.
-
(1994)
Cancer Res.
, vol.54
, pp. 5474-5478
-
-
Culig, Z.1
Hobisch, A.2
Cronauer, M.V.3
-
23
-
-
0033022342
-
A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase
-
CRAFT N, SHOSTAK Y, CAREY M, SAWYERS CL: A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase. Nat. Med. (1999) 5:280-285.
-
(1999)
Nat. Med.
, vol.5
, pp. 280-285
-
-
Craft, N.1
Shostak, Y.2
Carey, M.3
Sawyers, C.L.4
-
24
-
-
0029814415
-
Activation of the human androgen receptor through a protein kinase A signaling pathway
-
NAZARETH LV, WEIGEL NL: Activation of the human androgen receptor through a protein kinase A signaling pathway. J. Biol. Chem. (1996) 271:19900-19907.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 19900-19907
-
-
Nazareth, L.V.1
Weigel, N.L.2
-
25
-
-
0036091221
-
17-Allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and HER-2/neu and inhibits the growth of prostate cancer xenografts
-
SOLIT DB, ZHENG FF, DROBNJAK M et al.: 17-Allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and HER-2/neu and inhibits the growth of prostate cancer xenografts. Clin. Cancer Res. (2002) 8:986-993.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 986-993
-
-
Solit, D.B.1
Zheng, F.F.2
Drobnjak, M.3
-
26
-
-
6344294360
-
Silencing of androgen-regulated genes using a fusion of AR with the PLZF transcriptional repressor
-
PIKE J, HOLMES D, KAMALATI T et al.: Silencing of androgen-regulated genes using a fusion of AR with the PLZF transcriptional repressor. Oncogene (2004) 23:7561-7570.
-
(2004)
Oncogene
, vol.23
, pp. 7561-7570
-
-
Pike, J.1
Holmes, D.2
Kamalati, T.3
-
27
-
-
0029154151
-
Detection and characterization of the prostate-specific membrane antigen (PSMA) in tissue extracts and body fluids
-
TROYER JK, BECKETT ML, WRIGHT GL, JR.: Detection and characterization of the prostate-specific membrane antigen (PSMA) in tissue extracts and body fluids. Int. J. Cancer (1995) 62:552-558.
-
(1995)
Int. J. Cancer
, vol.62
, pp. 552-558
-
-
Troyer, J.K.1
Beckett, M.L.2
Wright Jr., G.L.3
-
28
-
-
0028851577
-
Localization and physical mapping of the prostate-specific membrane antigen (PSM) gene to human chromosome 11
-
RINKER-SCHAEFFER CW, HAWKINS AL, SU SL et al.: Localization and physical mapping of the prostate-specific membrane antigen (PSM) gene to human chromosome 11. Genomics (1995) 30:105-108.
-
(1995)
Genomics
, vol.30
, pp. 105-108
-
-
Rinker-Schaeffer, C.W.1
Hawkins, A.L.2
Su, S.L.3
-
29
-
-
0030223004
-
Prostate-specific membrane antigen: A novel folate hydrolase in human prostatic carcinoma cells
-
PINTO JT, SUFFOLETTO BP, BERZIN TM et al.: Prostate-specific membrane antigen: a novel folate hydrolase in human prostatic carcinoma cells. Clin. Cancer Res. (1996) 2:1445-1451.
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 1445-1451
-
-
Pinto, J.T.1
Suffoletto, B.P.2
Berzin, T.M.3
-
30
-
-
0030219893
-
Upregulation of prostate-specific membrane antigen after androgen-deprivation therapy
-
WRIGHT GL, JR., GROB BM, HALEY C et al.: Upregulation of prostate-specific membrane antigen after androgen-deprivation therapy. Urology (1996) 48:326-334.
-
(1996)
Urology
, vol.48
, pp. 326-334
-
-
Wright Jr., G.L.1
Grob, B.M.2
Haley, C.3
-
31
-
-
0028281780
-
Expression of the prostate-specific membrane antigen
-
ISRAELI RS, POWELL CT, CORR JG, FAIR WR, HESTON WD: Expression of the prostate-specific membrane antigen. Cancer Res. (1994) 54:1807-1811.
-
(1994)
Cancer Res.
, vol.54
, pp. 1807-1811
-
-
Israeli, R.S.1
Powell, C.T.2
Corr, J.G.3
Fair, W.R.4
Heston, W.D.5
-
32
-
-
0032188742
-
Prostate-specific membrane antigen expression is greatest in prostate adenocarcinoma and lymph node metastases
-
SWEAT SD, PACELLI A, MURPHY GP, BOSTWICK DG: Prostate-specific membrane antigen expression is greatest in prostate adenocarcinoma and lymph node metastases. Urology (1998) 52:637-640.
-
(1998)
Urology
, vol.52
, pp. 637-640
-
-
Sweat, S.D.1
Pacelli, A.2
Murphy, G.P.3
Bostwick, D.G.4
-
33
-
-
0033168844
-
Five different anti-prostate-specific membrane antigen (PSMA) antibodies confirm PSMA expression in tumor-associated neovasculature
-
CHANG SS, REUTER VE, HESTON WD et al.: Five different anti-prostate-specific membrane antigen (PSMA) antibodies confirm PSMA expression in tumor-associated neovasculature. Cancer Res. (1999) 59:3192-3198.
-
(1999)
Cancer Res.
, vol.59
, pp. 3192-3198
-
-
Chang, S.S.1
Reuter, V.E.2
Heston, W.D.3
-
34
-
-
18144407168
-
Anti-PSMA mAb huJ591 specifically targets tumor vascular endothelial cells in patients with advanced solid tumor malignancies
-
MILOWSKY MI, ROSMARIN AS, COBHAM MV et al.: Anti-PSMA mAb huJ591 specifically targets tumor vascular endothelial cells in patients with advanced solid tumor malignancies. Proceedings of American Society of Clinical Oncology. 21. 2002.
-
(2002)
Proceedings of American Society of Clinical Oncology
, pp. 21
-
-
Milowsky, M.I.1
Rosmarin, A.S.2
Cobham, M.V.3
-
35
-
-
18144402745
-
Targeting metastatic prostate cancer with radiolabeled monoclonal antibody J591 to the extracellular domain of prostate specific membrane antigen
-
RITTER MP: Targeting metastatic prostate cancer with radiolabeled monoclonal antibody J591 to the extracellular domain of prostate specific membrane antigen Urol.Oncol. (2004) 22:384.
-
(2004)
Urol. Oncol.
, vol.22
, pp. 384
-
-
Ritter, M.P.1
-
36
-
-
0032091741
-
111Indium-capromab pendetide in the evaluation of patients with residual or recurrent prostate cancer after radical prostatectomy
-
The ProstaScint Study Group
-
KAHN D, WILLIAMS RD, MANYAK MJ et al.: 111Indium-capromab pendetide in the evaluation of patients with residual or recurrent prostate cancer after radical prostatectomy. The ProstaScint Study Group. J. Urol. (1998) 159:2041-2046.
-
(1998)
J. Urol.
, vol.159
, pp. 2041-2046
-
-
Kahn, D.1
Williams, R.D.2
Manyak, M.J.3
-
37
-
-
0141919750
-
Targeting metastatic prostate cancer with radiolabeled monoclonal antibody J591 to the extracellular domain of prostate specific membrane antigen
-
BANDER NH, TRABULSI EJ, KOSTAKOGLU L et al.: Targeting metastatic prostate cancer with radiolabeled monoclonal antibody J591 to the extracellular domain of prostate specific membrane antigen. J. Urol. (2003) 170:1717-1721.
-
(2003)
J. Urol.
, vol.170
, pp. 1717-1721
-
-
Bander, N.H.1
Trabulsi, E.J.2
Kostakoglu, L.3
-
38
-
-
4344618391
-
Phase I Trial of Yttrium-90-Labeled Anti-Prostate-Specific Membrane Antigen Monoclonal Antibody J591 for Androgen-Independent Prostate Cancer
-
MILOWSKY MI, NANUS DM, KOSTAKOGLU L et al.: Phase I Trial of Yttrium-90-Labeled Anti-Prostate-Specific Membrane Antigen Monoclonal Antibody J591 for Androgen-Independent Prostate Cancer. J. Clin. Oncol. (2004) 22:2522-2531.
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 2522-2531
-
-
Milowsky, M.I.1
Nanus, D.M.2
Kostakoglu, L.3
-
39
-
-
1042306331
-
Phase I radioimmunotherapy (RIT) trial of humanized monoclonal (mAb) antibody J591 to the extracellular domain of prostate specific membrane antigen (PSMAext) radiolabeled with 177leutetium (177Lu) in advanced prostate cancer (Pca)
-
BANDER NH, NANUS DM, MILOWSKY MI et al.: Phase I radioimmunotherapy (RIT) trial of humanized monoclonal (mAb) antibody J591 to the extracellular domain of prostate specific membrane antigen (PSMAext) radiolabeled with 177leutetium (177Lu) in advanced prostate cancer (Pca). Proceedings of American Society of Clinical Oncology 22, 401. 2003.
-
(2003)
Proceedings of American Society of Clinical Oncology
, vol.22
, pp. 401
-
-
Bander, N.H.1
Nanus, D.M.2
Milowsky, M.I.3
-
41
-
-
7444263583
-
A prostate-specific membrane antigen-targeted monoclonal antibody-chemotherapeutic conjugate designed for the treatment of prostate cancer
-
HENRY MD, WEN S, SILVA MD et al.: A prostate-specific membrane antigen-targeted monoclonal antibody-chemotherapeutic conjugate designed for the treatment of prostate cancer. Cancer Res. (2004) 64:7995-8001.
-
(2004)
Cancer Res.
, vol.64
, pp. 7995-8001
-
-
Henry, M.D.1
Wen, S.2
Silva, M.D.3
-
42
-
-
0142030952
-
Targeted systemic therapy of prostate cancer with a monoclonal antibody to prostate-specific membrane antigen
-
BANDER NH, NANUS DM, MILOWSKY MI et al.: Targeted systemic therapy of prostate cancer with a monoclonal antibody to prostate-specific membrane antigen. Semin. Oncol (2003) 30:667-676.
-
(2003)
Semin. Oncol.
, vol.30
, pp. 667-676
-
-
Bander, N.H.1
Nanus, D.M.2
Milowsky, M.I.3
-
43
-
-
18144364234
-
Phase II trial of monoclonal antibody huJ591 in combination with low dose subcutaneous interleukin-2 in patients with recurrent prostate cancer (PC)
-
NANUS DM, MILOWSKY MI, ROSMARIN AS et al.: Phase II trial of monoclonal antibody huJ591 in combination with low dose subcutaneous interleukin-2 in patients with recurrent prostate cancer (PC). Proceedings of American Society of Clinical Oncology 21. 2002.
-
(2002)
Proceedings of American Society of Clinical Oncology
, pp. 21
-
-
Nanus, D.M.1
Milowsky, M.I.2
Rosmarin, A.S.3
-
44
-
-
0033848703
-
Expression of prostate-specific antigen and human glandular kallikrein 2 in the thyroid gland
-
MAGKLARA A, CHEUNG CC, ASA SL, DIAMANDIS EP: Expression of prostate-specific antigen and human glandular kallikrein 2 in the thyroid gland. Clin. Chim. Acta (2000) 300:171-180.
-
(2000)
Clin. Chim. Acta
, vol.300
, pp. 171-180
-
-
Magklara, A.1
Cheung, C.C.2
Asa, S.L.3
Diamandis, E.P.4
-
45
-
-
0033526309
-
Natural history of progression after PSA elevation following radical prostatectomy
-
POUND CR, PARTIN AW, EISENBERGER MA et al.: Natural history of progression after PSA elevation following radical prostatectomy. JAMA (1999) 281:1591-1597.
-
(1999)
JAMA
, vol.281
, pp. 1591-1597
-
-
Pound, C.R.1
Partin, A.W.2
Eisenberger, M.A.3
-
46
-
-
0030913316
-
Prostate cancer detection in men with serum PSA concentrations of 2.6 to 4.0 ng/mL and benign prostate examination. Enhancement of specificity with free PSA measurements
-
CATALONA WJ, SMITH DS, ORNSTEIN DK: Prostate cancer detection in men with serum PSA concentrations of 2.6 to 4.0 ng/mL and benign prostate examination. Enhancement of specificity with free PSA measurements. JAMA (1997) 277:1452-1455.
-
(1997)
JAMA
, vol.277
, pp. 1452-1455
-
-
Catalona, W.J.1
Smith, D.S.2
Ornstein, D.K.3
-
47
-
-
0000084631
-
The Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial
-
GOHAGAN JK, LEVIN D, PROROK PC, SULLIVAN D: The Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial. Control Clin. Trials (2001) 21(Suppl):249S-406S.
-
(2001)
Control Clin. Trials
, vol.21
, Issue.SUPPL.
-
-
Gohagan, J.K.1
Levin, D.2
Prorok, P.C.3
Sullivan, D.4
-
48
-
-
0026077430
-
Prostate-specific antigen in serum occurs predominantly in complex with alpha 1-antichymotrypsin
-
LILJA H, CHRISTENSSON A, DAHLEN U et al.: Prostate-specific antigen in serum occurs predominantly in complex with alpha 1-antichymotrypsin. Clin. Chem. (1991) 37:1618-1625.
-
(1991)
Clin. Chem.
, vol.37
, pp. 1618-1625
-
-
Lilja, H.1
Christensson, A.2
Dahlen, U.3
-
49
-
-
0030728733
-
Specific and efficient peptide substrates for assaying the proteolytic activity of prostate-specific antigen
-
DENMEADE SR, LOU W, LOVGREN J et al.: Specific and efficient peptide substrates for assaying the proteolytic activity of prostate-specific antigen. Cancer Res. (1997) 57:4924-4930.
-
(1997)
Cancer Res.
, vol.57
, pp. 4924-4930
-
-
Denmeade, S.R.1
Lou, W.2
Lovgren, J.3
-
50
-
-
0036533873
-
Characterization of a Novel Prostate-Specific Antigen-Activated Peptide-Doxorubicin Conjugate in Patients With Prostate Cancer
-
DIPAOLA RS, RINEHART J, NEMUNAITIS J et al.: Characterization of a Novel Prostate-Specific Antigen-Activated Peptide-Doxorubicin Conjugate in Patients With Prostate Cancer. J. Clin. Oncol. (2002) 20:1874-1879.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 1874-1879
-
-
Dipaola, R.S.1
Rinehart, J.2
Nemunaitis, J.3
-
51
-
-
0035111756
-
PSA-Specific and Non-PSA-Specific Conversion of a PSA Targeted Peptide Conjugate of Doxorubicin to Its Active Metabolites
-
WONG BK, DEFEO-JONES D, JONES RE et al.: PSA-Specific and Non-PSA-Specific Conversion of a PSA Targeted Peptide Conjugate of Doxorubicin to Its Active Metabolites. Drug Metab. Dispos. (2001) 29:313-318.
-
(2001)
Drug Metab. Dispos.
, vol.29
, pp. 313-318
-
-
Wong, B.K.1
Defeo-Jones, D.2
Jones, R.E.3
-
52
-
-
0028143317
-
The role of calcium, pH, and cell proliferation in the programmed (apoptotic) death of androgen-independent prostatic cancer cells induced by thapsigargin
-
FURUYA Y, LUNDMO P, SHORT AD, GILL DL, ISAACS JT: The role of calcium, pH, and cell proliferation in the programmed (apoptotic) death of androgen-independent prostatic cancer cells induced by thapsigargin. Cancer Res. (1994) 54:6167-6175.
-
(1994)
Cancer Res.
, vol.54
, pp. 6167-6175
-
-
Furuya, Y.1
Lundmo, P.2
Short, A.D.3
Gill, D.L.4
Isaacs, J.T.5
-
53
-
-
0042308774
-
Prostate-Specific Antigen-Activated Thapsigargin Prodrug as Targeted Therapy for Prostate Cancer
-
DENMEADE SR, JAKOBSEN CM, JANSSEN S et al.: Prostate-Specific Antigen-Activated Thapsigargin Prodrug as Targeted Therapy for Prostate Cancer. J. Natl Cancer Inst. (2003) 95:990-1000.
-
(2003)
J. Natl. Cancer Inst.
, vol.95
, pp. 990-1000
-
-
Denmeade, S.R.1
Jakobsen, C.M.2
Janssen, S.3
-
54
-
-
0035887153
-
A Phase I Trial of CV706, a Replication-competent, PSA Selective Oncolytic Adenovirus, for the Treatment of Locally Recurrent Prostate Cancer following Radiation Therapy
-
DEWEESE TL, VAN DER POEL H, LI S et al.: A Phase I Trial of CV706, a Replication-competent, PSA Selective Oncolytic Adenovirus, for the Treatment of Locally Recurrent Prostate Cancer following Radiation Therapy. Cancer Res. (2001) 61:7464-7472.
-
(2001)
Cancer Res.
, vol.61
, pp. 7464-7472
-
-
Deweese, T.L.1
Van Der Poel, H.2
Li, S.3
-
55
-
-
0033199188
-
The addition of adenovirus Type 5 region E3 enables calydon virus 787 to eliminate distant prostate tumor xenografts
-
YU DC, CHEN Y, SENG M, DILLEY J, HENDERSON DR: The addition of adenovirus Type 5 region E3 enables calydon virus 787 to eliminate distant prostate tumor xenografts. Cancer Res. (1999) 59:4200-4203.
-
(1999)
Cancer Res.
, vol.59
, pp. 4200-4203
-
-
Yu, D.C.1
Chen, Y.2
Seng, M.3
Dilley, J.4
Henderson, D.R.5
-
56
-
-
0035863499
-
Antitumor synergy of CV787, a prostate cancer-specific adenovirus, and paclitaxel and docetaxel
-
YU DC, CHEN Y, DILLEY J et al.: Antitumor synergy of CV787, a prostate cancer-specific adenovirus, and paclitaxel and docetaxel. Cancer Res. (2001) 61:517-525.
-
(2001)
Cancer Res.
, vol.61
, pp. 517-525
-
-
Yu, D.C.1
Chen, Y.2
Dilley, J.3
-
57
-
-
0036787490
-
Phase I study of a vaccine using recombinant vaccinia virus expressing PSA (rV-PSA) in patients with metastatic androgen-independent prostate cancer
-
GULLEY J, CHEN AP, DAHUT W et al.: Phase I study of a vaccine using recombinant vaccinia virus expressing PSA (rV-PSA) in patients with metastatic androgen-independent prostate cancer. Prostate (2002) 53:109-117.
-
(2002)
Prostate
, vol.53
, pp. 109-117
-
-
Gulley, J.1
Chen, A.P.2
Dahut, W.3
-
58
-
-
17444440950
-
A Phase I trial of a recombinant vaccinia virus expressing prostate-specific antigen in advanced prostate cancer
-
EDER JP, KANTOFF PW, ROPER K et al.: A Phase I trial of a recombinant vaccinia virus expressing prostate-specific antigen in advanced prostate cancer. Clin. Cancer Res. (2000) 6:1632-1638.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 1632-1638
-
-
Eder, J.P.1
Kantoff, P.W.2
Roper, K.3
-
59
-
-
4344672484
-
A Phase I trial of DNA vaccination with a plasmid expressing prostate-specific antigen in patients with hormone-refractory prostate cancer
-
PAVLENKO M, ROOS AK, LUNDQVIST A et al.: A Phase I trial of DNA vaccination with a plasmid expressing prostate-specific antigen in patients with hormone-refractory prostate cancer. Br. J. Cancer (2004) 91:688-694.
-
(2004)
Br. J. Cancer
, vol.91
, pp. 688-694
-
-
Pavlenko, M.1
Roos, A.K.2
Lundqvist, A.3
-
60
-
-
2942644684
-
Phase II randomized study of vaccine treatment of advanced prostate cancer (E7897): A trial of the Eastern Cooperative Oncology Group
-
KAUFMAN HL, WANG W, MANOLA J et al.: Phase II randomized study of vaccine treatment of advanced prostate cancer (E7897): a trial of the Eastern Cooperative Oncology Group. J. Clin. Oncol. (2004) 22:2122-2132.
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 2122-2132
-
-
Kaufman, H.L.1
Wang, W.2
Manola, J.3
-
61
-
-
0032747375
-
Eligibility and Response Guidelines for Phase II Clinical Trials in Androgen-Independent Prostate Cancer: Recommendations From the Prostate-Specific Antigen Working Group
-
BUBLEY GJ, CARDUCCI M, DAHUT W et al.: Eligibility and Response Guidelines for Phase II Clinical Trials in Androgen-Independent Prostate Cancer: Recommendations From the Prostate-Specific Antigen Working Group. J. Clin. Oncol. (1999) 17:3461-3467.
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 3461-3467
-
-
Bubley, G.J.1
Carducci, M.2
Dahut, W.3
-
62
-
-
0034043167
-
Priming tissue-specific cellular immunity in a Phase I trial of autologous dendritic cells for prostate cancer
-
BURCH PA, BREEN JK, BUCKNER JC et al.: Priming tissue-specific cellular immunity in a Phase I trial of autologous dendritic cells for prostate cancer. Clin. Cancer Res. (2000) 6:2175-2182.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 2175-2182
-
-
Burch, P.A.1
Breen, J.K.2
Buckner, J.C.3
-
63
-
-
0034554863
-
Immunotherapy of Hormone-Refractory Prostate Cancer With Antigen-Loaded Dendritic Cells
-
SMALL EJ, FRATESI P, REESE DM et al.: Immunotherapy of Hormone-Refractory Prostate Cancer With Antigen-Loaded Dendritic Cells. J. Clin. Oncol. (2000) 18:3894-3903.
-
(2000)
J. Clin. Oncol.
, vol.18
, pp. 3894-3903
-
-
Small, E.J.1
Fratesi, P.2
Reese, D.M.3
-
64
-
-
3242747658
-
Immunotherapy (APC8015, Provenge(R)) targeting prostatic acid phosphatase can induce durable remission of metastatic androgen-independent prostate cancer: A Phase II trial
-
BURCH PA, CROGHAN GA, GASTINEAU DA et al.: Immunotherapy (APC8015, Provenge(R)) targeting prostatic acid phosphatase can induce durable remission of metastatic androgen-independent prostate cancer: A Phase II trial. Prostate (2004) 60:197-204.
-
(2004)
Prostate
, vol.60
, pp. 197-204
-
-
Burch, P.A.1
Croghan, G.A.2
Gastineau, D.A.3
-
65
-
-
18144375483
-
A placebo-controlled Phase III trial of immunotherapy (APC8015, Provenge®) for androgen independent prostate cancer (AIPC): Evidence that Gleason Score predicts immunologic as well as clinical responses to therapy
-
[abstract]
-
KYLSTRA JW, NEMUNAITIS J, SMALL EJ, JONES LA: A placebo-controlled Phase III trial of immunotherapy (APC8015, Provenge®) for androgen independent prostate cancer (AIPC): Evidence that Gleason Score predicts immunologic as well as clinical responses to therapy [abstract]. Proceedings of the AACR 2004;45.
-
(2004)
Proceedings of the AACR
, pp. 45
-
-
Kylstra, J.W.1
Nemunaitis, J.2
Small, E.J.3
Jones, L.A.4
-
67
-
-
0035152120
-
GSTP1 CpG island hypermethylation is responsible for the absence of GSTP1 expression in human prostate cancer cells
-
LIN X, TASCILAR M, LEE WH et al.: GSTP1 CpG island hypermethylation is responsible for the absence of GSTP1 expression in human prostate cancer cells. Am. J. Pathol. (2001) 159:1815-1826.
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 1815-1826
-
-
Lin, X.1
Tascilar, M.2
Lee, W.H.3
-
68
-
-
0034970071
-
The molecular pathogenesis of prostate cancer: Implications for prostate cancer prevention
-
NELSON WG, DE MARZO AM, DEWEESE TL: The molecular pathogenesis of prostate cancer: Implications for prostate cancer prevention. Urology (2001) 57:39-45.
-
(2001)
Urology
, vol.57
, pp. 39-45
-
-
Nelson, W.G.1
De Marzo, A.M.2
Deweese, T.L.3
-
69
-
-
0010607277
-
The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers
-
THE ALPHA-TOCOPHEROL, BETA CAROTENE CANCER PREVENTION STUDY GROUP
-
THE ALPHA-TOCOPHEROL, BETA CAROTENE CANCER PREVENTION STUDY GROUP: The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N. Engl. J. Med. (1994) 330:1029-1035.
-
(1994)
N. Engl. J. Med.
, vol.330
, pp. 1029-1035
-
-
-
70
-
-
0032542759
-
Prostate cancer and supplementation with alpha-tocopherol and beta-carotene: Incidence and mortality in a controlled trial
-
HEINONEN OP, ALBANES D, VIRTAMO J et al.: Prostate cancer and supplementation with alpha-tocopherol and beta-carotene: incidence and mortality in a controlled trial. J. Natl. Cancer Inst. (1998) 90:440-446.
-
(1998)
J. Natl. Cancer Inst.
, vol.90
, pp. 440-446
-
-
Heinonen, O.P.1
Albanes, D.2
Virtamo, J.3
-
71
-
-
2342626088
-
Update on chemoprevention of prostate cancer
-
KLEIN EA, THOMPSON IM: Update on chemoprevention of prostate cancer. Curr. Opin. Urol. (2004) 14:143-149.
-
(2004)
Curr. Opin. Urol.
, vol.14
, pp. 143-149
-
-
Klein, E.A.1
Thompson, I.M.2
-
73
-
-
0027171632
-
Homozygous deletion and frequent allelic loss of chromosome 8p22 loci in human prostate cancer
-
BOVA GS, CARTER BS, BUSSEMAKERS JG et al.: Homozygous deletion and frequent allelic loss of chromosome 8p22 loci in human prostate cancer. Cancer Res. (1993) 53:3869-3873.
-
(1993)
Cancer Res.
, vol.53
, pp. 3869-3873
-
-
Bova, G.S.1
Carter, B.S.2
Bussemakers, J.G.3
-
74
-
-
0029067371
-
Allelic loss on chromosome 8p12-21 in microdissected prostate intraepithelial neoplasia
-
EMMERT-BUCK MR, VOCKE CD, POZZATTI RO et al.: Allelic loss on chromosome 8p12-21 in microdissected prostate intraepithelial neoplasia. Cancer Res. (1995) 55:2959-2962.
-
(1995)
Cancer Res.
, vol.55
, pp. 2959-2962
-
-
Emmert-Buck, M.R.1
Vocke, C.D.2
Pozzatti, R.O.3
-
75
-
-
9344222738
-
Analysis of 99 microdissected prostate carcinomas reveals a high frequency of allelic loss on chromosome 8p21-22
-
VOCKE CD, POZZATTI RO, BOSTWICK DG et al.: Analysis of 99 microdissected prostate carcinomas reveals a high frequency of allelic loss on chromosome 8p21-22. Cancer Res. (1996) 56:2411-2416.
-
(1996)
Cancer Res.
, vol.56
, pp. 2411-2416
-
-
Vocke, C.D.1
Pozzatti, R.O.2
Bostwick, D.G.3
-
76
-
-
18244386765
-
Determination of a minimal deletion interval on chromosome band 8p21 in sporadic prostate cancer
-
SWALWELL JI, VOCKE CD, YANG Y et al.: Determination of a minimal deletion interval on chromosome band 8p21 in sporadic prostate cancer. Genes Chromosomes. Cancer (2002) 33:201-205.
-
(2002)
Genes Chromosomes. Cancer
, vol.33
, pp. 201-205
-
-
Swalwell, J.I.1
Vocke, C.D.2
Yang, Y.3
-
77
-
-
0034326839
-
Loss of NKX3.1 expression in human prostate cancers correlates with tumor progression
-
BOWEN C, BUBENDORF L, VOELLER HJ et al.: Loss of NKX3.1 expression in human prostate cancers correlates with tumor progression. Cancer Res. (2000) 60:6111-6115.
-
(2000)
Cancer Res.
, vol.60
, pp. 6111-6115
-
-
Bowen, C.1
Bubendorf, L.2
Voeller, H.J.3
-
78
-
-
13944249886
-
Deletion, methylation and expression of the NKX3.1 suppressor gene in primary human prostate cancer
-
ASATIANI E, HUANG W -X, WANG A et al.: Deletion, methylation and expression of the NKX3.1 suppressor gene in primary human prostate cancer. Cancer Res. (2005) 65:1164-1173.
-
(2005)
Cancer Res.
, vol.65
, pp. 1164-1173
-
-
Asatiani, E.1
Huang, W.-X.2
Wang, A.3
-
79
-
-
0030822020
-
Coding region of NKX3.1, prostate-specific homeobox gene on 8p21, is not mutated in human prostate cancers
-
VOELLER HJ, AUGUSTUS M, MADLIKE V et al.: Coding region of NKX3.1, prostate-specific homeobox gene on 8p21, is not mutated in human prostate cancers. Cancer Res. (1997) 57:4455-4459.
-
(1997)
Cancer Res.
, vol.57
, pp. 4455-4459
-
-
Voeller, H.J.1
Augustus, M.2
Madlike, V.3
-
80
-
-
0035091517
-
Expression studies and mutational analysis of the androgen regulated homeobox gene nkx3.1 in benign and malignant prostate epithelium
-
ORNSTEIN DK, CINQUANTA M, WEILER S et al.: Expression studies and mutational analysis of the androgen regulated homeobox gene nkx3.1 in benign and malignant prostate epithelium. J. Urol. (2001) 165:1329-1334.
-
(2001)
J. Urol.
, vol.165
, pp. 1329-1334
-
-
Ornstein, D.K.1
Cinquanta, M.2
Weiler, S.3
-
82
-
-
0037022663
-
Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis
-
KIM MJ, CARDIFF RD, DESAI N et al.: Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis. Proc. Natl. Acad. Sci. USA (2002) 99:2884-2889.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 2884-2889
-
-
Kim, M.J.1
Cardiff, R.D.2
Desai, N.3
-
83
-
-
0042787650
-
Haploinsufficiency at the Nkx3.1 locus. A paradigm forstochastic, dosage-sensitive gene regulation during tumor initiation
-
MAGEE JA, ABDULKADIR SA, MILBRANDT J: Haploinsufficiency at the Nkx3.1 locus. A paradigm forstochastic, dosage-sensitive gene regulation during tumor initiation. Cancer Cell (2003) 3:273-283.
-
(2003)
Cancer Cell
, vol.3
, pp. 273-283
-
-
Magee, J.A.1
Abdulkadir, S.A.2
Milbrandt, J.3
-
84
-
-
18344389720
-
Causal relationship between the loss of RUNX3 expression and gastric cancer
-
LI QL, ITO K, SAKAKURA C et al.: Causal relationship between the loss of RUNX3 expression and gastric cancer. Cell (2002) 109:113-124.
-
(2002)
Cell
, vol.109
, pp. 113-124
-
-
Li, Q.L.1
Ito, K.2
Sakakura, C.3
-
86
-
-
0025223062
-
Allelic loss of chromosomes 16q and 10q in human prostate cancer
-
CARTER BS, EWING CM, WARD WS et al.: Allelic loss of chromosomes 16q and 10q in human prostate cancer. Proc. Natl. Acad. Sci. USA (1990) 87:8751-8755.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 8751-8755
-
-
Carter, B.S.1
Ewing, C.M.2
Ward, W.S.3
-
87
-
-
0032473921
-
Analysis of PTEN and the 10q23 region in primary prostate carcinomas
-
FEILOTTER HE, NAGAI MA, BOAG AH, ENG C, MULLIGAN LM: Analysis of PTEN and the 10q23 region in primary prostate carcinomas. Oncogene (1998) 16:1743-1748.
-
(1998)
Oncogene
, vol.16
, pp. 1743-1748
-
-
Feilotter, H.E.1
Nagai, M.A.2
Boag, A.H.3
Eng, C.4
Mulligan, L.M.5
-
88
-
-
18144393351
-
Loss of heterozygosity on chromosome 10q is associated with malignant melanoma
-
AB 3428
-
HERBST RA, WEISS J, EHNIS A, CAVENEE WK, ARDEN KC: Loss of heterozygosity on chromosome 10q is associated with malignant melanoma. Proc. Amer. Assoc. Cancer Res. (1994) 35:575 AB 3428.
-
(1994)
Proc. Amer. Assoc. Cancer Res.
, vol.35
, pp. 575
-
-
Herbst, R.A.1
Weiss, J.2
Ehnis, A.3
Cavenee, W.K.4
Arden, K.C.5
-
89
-
-
0023790852
-
Multiple structural chromosome rearrangements, including del(7q) and del(10q), in an adenocarcinoma of the prostate
-
LUNDGREN R, KRISTOFFERSSON U, HEIM S, MANDAHL N, MITELMAN F: Multiple structural chromosome rearrangements, including del(7q) and del(10q), in an adenocarcinoma of the prostate. Cancer Genet. Cytogenet. (1988) 35:103-108.
-
(1988)
Cancer Genet. Cytogenet.
, vol.35
, pp. 103-108
-
-
Lundgren, R.1
Kristoffersson, U.2
Heim, S.3
Mandahl, N.4
Mitelman, F.5
-
90
-
-
15444349266
-
Frequent inactivation of PTEN/MMAC1 in primary prostate cancer
-
CAIRNS P, OKAMI K, HALACHMI S et al.: Frequent inactivation of PTEN/MMAC1 in primary prostate cancer. Cancer Res. (1997) 57:4997-5000.
-
(1997)
Cancer Res.
, vol.57
, pp. 4997-5000
-
-
Cairns, P.1
Okami, K.2
Halachmi, S.3
-
91
-
-
0032532552
-
PTEN/MMAC1 is infrequently mutated in pT2 and pT3 carcinomas of the prostate
-
DONG JT, SIPE TW, HYYTINEN ER et al.: PTEN/MMAC1 is infrequently mutated in pT2 and pT3 carcinomas of the prostate. Oncogene (1998) 17:1979-1982.
-
(1998)
Oncogene
, vol.17
, pp. 1979-1982
-
-
Dong, J.T.1
Sipe, T.W.2
Hyytinen, E.R.3
-
92
-
-
0035126875
-
Mutations of PTEN/MMAC1 in primary prostate cancers from Chinese patients
-
DONG JT, LI CL, SIPE TW, FRIERSON HF, JR.: Mutations of PTEN/MMAC1 in primary prostate cancers from Chinese patients. Clin. Cancer Res. (2001) 7:304-308.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 304-308
-
-
Dong, J.T.1
Li, C.L.2
Sipe, T.W.3
Frierson Jr., H.F.4
-
93
-
-
0031762207
-
Mutation and expression analysis of the putative prostate tumour-suppressor gene PTEN
-
GRAY IC, STEWART LM, PHILLIPS SM et al.: Mutation and expression analysis of the putative prostate tumour-suppressor gene PTEN. Br. J. Cancer (1998) 78:1296-1300.
-
(1998)
Br. J. Cancer
, vol.78
, pp. 1296-1300
-
-
Gray, I.C.1
Stewart, L.M.2
Phillips, S.M.3
-
94
-
-
0033200172
-
Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage
-
MCMENAMIN ME, SOUNG P, PERERA S et al.: Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage. Cancer Res. (1999) 59:4291-4296.
-
(1999)
Cancer Res.
, vol.59
, pp. 4291-4296
-
-
Mcmenamin, M.E.1
Soung, P.2
Perera, S.3
-
95
-
-
0031922369
-
Homozygous deletion of the PTEN tumor suppressor gene in a subset of prostate adenocarcinomas
-
WANG SI, PARSONS R, ITTMANN M: Homozygous deletion of the PTEN tumor suppressor gene in a subset of prostate adenocarcinomas. Clin. Cancer Res. (1998) 4:811-815.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 811-815
-
-
Wang, S.I.1
Parsons, R.2
Ittmann, M.3
-
96
-
-
0032574718
-
Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression
-
WHANG YE, WU X, SUZUKI H et al.: Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression. Proc. Natl. Acad. Sci. USA (1998) 95:5246-5250.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 5246-5250
-
-
Whang, Y.E.1
Wu, X.2
Suzuki, H.3
-
97
-
-
0043244937
-
Nkx3.1; Pten mutant mice develop invasive prostate adenocarcinoma and lymph node metastases
-
ABATE-SHEN C, BANACH-PETROSKY WA, SUN X et al.: Nkx3.1; Pten mutant mice develop invasive prostate adenocarcinoma and lymph node metastases. Cancer Res. (2003) 63:3886-3890.
-
(2003)
Cancer Res.
, vol.63
, pp. 3886-3890
-
-
Abate-Shen, C.1
Banach-Petrosky, W.A.2
Sun, X.3
-
98
-
-
0034746302
-
Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse
-
DI CRISTOFANO A, DE ACETIS M, KOFF A, CORDON-CARDO C, PANDOLFI PP: Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse. Nat. Genet. (2001) 27:222-224.
-
(2001)
Nat. Genet.
, vol.27
, pp. 222-224
-
-
Di Cristofano, A.1
De Acetis, M.2
Koff, A.3
Cordon-Cardo, C.4
Pandolfi, P.P.5
-
99
-
-
0035949707
-
Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression
-
KWABI-ADDO B, GIRI D, SCHMIDT K et al.: Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression. Proc. Natl. Acad. Sci. USA (2001) 98:11563-11568.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 11563-11568
-
-
Kwabi-Addo, B.1
Giri, D.2
Schmidt, K.3
-
100
-
-
13044250465
-
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems
-
PODSYPANINA K, ELLENSON LH, NEMES A et al.: Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems. Proc. Natl. Acad. Sci. USA (1999) 96:1563-1568.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 1563-1568
-
-
Podsypanina, K.1
Ellenson, L.H.2
Nemes, A.3
-
101
-
-
0033514509
-
Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway
-
RAMASWAMY S, NAKAMURA N, VAZQUEZ F et al.: Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway. Proc. Natl Acad. Sci USA (1999) 96:2110-2115.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 2110-2115
-
-
Ramaswamy, S.1
Nakamura, N.2
Vazquez, F.3
-
103
-
-
0037293542
-
Phosphatidylinositol 3-kinase and mek1/2 are necessary for insulin-like growth factor-I-induced vascular endothelial growth factor synthesis in prostate epithelial cells: A role for hypoxia-inducible factor-1?
-
BURROUGHS KD, OH J, BARRETT JC, DIAUGUSTINE RP: Phosphatidylinositol 3-kinase and mek1/2 are necessary for insulin-like growth factor-I-induced vascular endothelial growth factor synthesis in prostate epithelial cells: a role for hypoxia-inducible factor-1? Mol. Cancer Res. (2003) 1:312-322.
-
(2003)
Mol. Cancer Res.
, vol.1
, pp. 312-322
-
-
Burroughs, K.D.1
Oh, J.2
Barrett, J.C.3
Diaugustine, R.P.4
-
104
-
-
0029079275
-
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
-
FRANKE TF, YANG SI, CHAN TO et al.: The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell (1995) 81:727-736.
-
(1995)
Cell
, vol.81
, pp. 727-736
-
-
Franke, T.F.1
Yang, S.I.2
Chan, T.O.3
-
105
-
-
0034671668
-
HER-2/neu Promotes Androgen-independent Survival and Growth of Prostate Cancer Cells through the Akt Pathway
-
WEN Y, HU MCT, MAKINO K et al.: HER-2/neu Promotes Androgen-independent Survival and Growth of Prostate Cancer Cells through the Akt Pathway. Cancer Res. (2000) 60:6841-6845.
-
(2000)
Cancer Res.
, vol.60
, pp. 6841-6845
-
-
Wen, Y.1
Hu, M.C.T.2
Makino, K.3
-
106
-
-
0037564511
-
Interleukin-6 differentially regulates androgen receptor transactivation via PI3K-Akt, STAT3, and MAPK, three distinct signal pathways in prostate cancer cells
-
YANG L, WANG L, LIN HK et al.: Interleukin-6 differentially regulates androgen receptor transactivation via PI3K-Akt, STAT3, and MAPK, three distinct signal pathways in prostate cancer cells. Biochem. Biophys. Res Commun. (2003) 305:462-469.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.305
, pp. 462-469
-
-
Yang, L.1
Wang, L.2
Lin, H.K.3
-
107
-
-
0035111828
-
Levels of insulin-like growth Factor I (IGF-I) and IGF binding proteins 2 and 3 in serial postoperative serum samples and risk of prostate cancer recurrence
-
YU H, NICAR MR, SHI R et al.: Levels of insulin-like growth Factor I (IGF-I) and IGF binding proteins 2 and 3 in serial postoperative serum samples and risk of prostate cancer recurrence. Urology (2001) 57:471-475.
-
(2001)
Urology
, vol.57
, pp. 471-475
-
-
Yu, H.1
Nicar, M.R.2
Shi, R.3
-
108
-
-
0037125383
-
Insulin-like growth factor-I (IGF-I) and IGF binding protein-3 as predictors of advanced-stage prostate cancer
-
CHAN JM, STAMPFER MJ, MA J et al.: Insulin-like growth factor-I (IGF-I) and IGF binding protein-3 as predictors of advanced-stage prostate cancer. J. Natl. Cancer Inst. (2002) 94:1099-1106.
-
(2002)
J. Natl. Cancer Inst.
, vol.94
, pp. 1099-1106
-
-
Chan, J.M.1
Stampfer, M.J.2
Ma, J.3
-
109
-
-
0027326228
-
Serum insulin-like growth factor-binding protein-2 (IGFBP-2) is increased and IGFBP-3 is decreased in patients with prostate cancer: Correlation with serum prostate-specific antigen
-
KANETY H, MADJAR Y, DAGAN Y et al.: Serum insulin-like growth factor-binding protein-2 (IGFBP-2) is increased and IGFBP-3 is decreased in patients with prostate cancer: correlation with serum prostate-specific antigen. J. Clin. Endocrinol. Metab. (1993) 77:229-233.
-
(1993)
J. Clin. Endocrinol. Metab.
, vol.77
, pp. 229-233
-
-
Kanety, H.1
Madjar, Y.2
Dagan, Y.3
-
110
-
-
0037304341
-
Serum insulin-like growth factor binding protein-3/prostate-specific antigen ratio is a useful predictive marker in patients with advanced prostate cancer
-
MIYATA Y, SAKAI H, HAYASHI T, KANETAKE H: Serum insulin-like growth factor binding protein-3/prostate-specific antigen ratio is a useful predictive marker in patients with advanced prostate cancer. Prostate (2003) 54:125-132.
-
(2003)
Prostate
, vol.54
, pp. 125-132
-
-
Miyata, Y.1
Sakai, H.2
Hayashi, T.3
Kanetake, H.4
-
111
-
-
0344010575
-
Relation of serum insulin-like growth factor-I (IGF-I) and IGF binding protein-3 to risk of prostate cancer (United States)
-
LI L, YU H, SCHUMACHER F, CASEY G, WITTE JS: Relation of serum insulin-like growth factor-I (IGF-I) and IGF binding protein-3 to risk of prostate cancer (United States). Cancer Causes Control (2003) 14:721-726.
-
(2003)
Cancer Causes Control
, vol.14
, pp. 721-726
-
-
Li, L.1
Yu, H.2
Schumacher, F.3
Casey, G.4
Witte, J.S.5
-
112
-
-
0042173160
-
Serum insulin-like growth Factor I: Tumor marker or etiologic factor? A prospective study of prostate cancer among Finnish men
-
WOODSON K, TANGREA JA, POLLAK M et al.: Serum insulin-like growth Factor I: tumor marker or etiologic factor? A prospective study of prostate cancer among Finnish men. Cancer Res. (2003) 63:3991-3994.
-
(2003)
Cancer Res.
, vol.63
, pp. 3991-3994
-
-
Woodson, K.1
Tangrea, J.A.2
Pollak, M.3
-
113
-
-
0344395149
-
Serum insulin-like growth factor (IGF)-1 and IGF-binding protein-3 do not correlate with Gleason score or quantity of prostate cancer in biopsy samples
-
ISMAIL HA, POLLAK M, BEHLOULI H et al.: Serum insulin-like growth factor (IGF)-1 and IGF-binding protein-3 do not correlate with Gleason score or quantity of prostate cancer in biopsy samples. BJU. Int. (2003) 92:699-702.
-
(2003)
BJU Int.
, vol.92
, pp. 699-702
-
-
Ismail, H.A.1
Pollak, M.2
Behlouli, H.3
-
114
-
-
0034637524
-
Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression
-
GRAFF JR, KONICEK BW, MCNULTY AM et al.: Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression. J. Mol. Chem. (2000) 275:24500-24505.
-
(2000)
J. Mol. Chem.
, vol.275
, pp. 24500-24505
-
-
Graff, J.R.1
Konicek, B.W.2
McNulty, A.M.3
-
115
-
-
0034749615
-
Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state
-
MURILLO H, HUANG H, SCHMIDT LJ, SMITH DI, TINDALL DJ: Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state. Endocrinology (2001) 142:4795-4805.
-
(2001)
Endocrinology
, vol.142
, pp. 4795-4805
-
-
Murillo, H.1
Huang, H.2
Schmidt, L.J.3
Smith, D.I.4
Tindall, D.J.5
-
116
-
-
3242755999
-
Molecular alterations associated with LNCaP cell progression to androgen independence
-
SHI XB, MA AH, TEPPER CG et al.: Molecular alterations associated with LNCaP cell progression to androgen independence. Prostate (2004) 60:257-271.
-
(2004)
Prostate
, vol.60
, pp. 257-271
-
-
Shi, X.B.1
Ma, A.H.2
Tepper, C.G.3
-
117
-
-
0036554734
-
Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer
-
MALIK SN, BRATTAIN M, GHOSH PM et al.: Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer. Clin. Cancer Res. (2002) 8:1168-1171.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 1168-1171
-
-
Malik, S.N.1
Brattain, M.2
Ghosh, P.M.3
-
118
-
-
0037103424
-
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
-
DEMETRI GD, VON MEHREN M, BLANKE CD et al.: Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N. Eng. J. Med. (2002) 347:472-480.
-
(2002)
N. Eng. J. Med.
, vol.347
, pp. 472-480
-
-
Demetri, G.D.1
Von Mehren, M.2
Blanke, C.D.3
-
119
-
-
0037103624
-
Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta
-
APPERLEY JF, GARDEMBAS M, MELO JV et al.: Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta. N. Engl. J. Med. (2002) 347:481-487.
-
(2002)
N. Engl. J. Med.
, vol.347
, pp. 481-487
-
-
Apperley, J.F.1
Gardembas, M.2
Melo, J.V.3
-
120
-
-
0037018763
-
Treatment of hypereosinophilic syndrome with imatinib mesilate
-
GLEICH GJ, LEIFERMAN KM, PARDANANI A, TEFFERI A, BUTTERFIELD JH: Treatment of hypereosinophilic syndrome with imatinib mesilate. Lancet (2002) 359:1577-1578.
-
(2002)
Lancet
, vol.359
, pp. 1577-1578
-
-
Gleich, G.J.1
Leiferman, K.M.2
Pardanani, A.3
Tefferi, A.4
Butterfield, J.H.5
-
121
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from 'never smokers' and are associated with sensitivity of tumors to gefitinib and erlotinib
-
PAO W, MILLER V, ZAKOWSKI M et al.: EGF receptor gene mutations are common in lung cancers from 'never smokers' and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc. Natl. Acad. Sci. USA (2004) 101:13306-13311.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
-
122
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
LYNCH TJ, BELL DW, SORDELLA R et al.: Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N. Eng. J. Med. (2004) 350:2129-2139.
-
(2004)
N. Eng. J. Med.
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
123
-
-
3543065879
-
Cetuximab: An IgG(1) monoclonal antibody for the treatment of epidermal growth factor receptor-expressing tumours
-
HUMBLET Y: Cetuximab: an IgG(1) monoclonal antibody for the treatment of epidermal growth factor receptor-expressing tumours. Expert. Opin. Pharmacother. (2004) 5:1621-1633.
-
(2004)
Expert. Opin. Pharmacother.
, vol.5
, pp. 1621-1633
-
-
Humblet, Y.1
-
124
-
-
5144220639
-
Successful targeting of ErbB2 receptors-is PTEN the key?
-
CROWDER RJ, LOMBARDI DP, ELLIS MJ: Successful targeting of ErbB2 receptors-is PTEN the key? Cancer Cell (2004) 6:103-104.
-
(2004)
Cancer Cell
, vol.6
, pp. 103-104
-
-
Crowder, R.J.1
Lombardi, D.P.2
Ellis, M.J.3
-
125
-
-
0034614108
-
Her-2-neu expression and progression toward androgen independence in human prostate cancer
-
SIGNORETTI S, MONTIRONI R, MANOLA J et al.: Her-2-neu expression and progression toward androgen independence in human prostate cancer. J. Natl Cancer Inst. (2000) 92:1918-1925.
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 1918-1925
-
-
Signoretti, S.1
Montironi, R.2
Manola, J.3
-
126
-
-
3242730201
-
Her-2/neu expression in prostate cancer: A dynamic process?
-
CARLES J, LLORETA J, SALIDO M et al.: Her-2/neu expression in prostate cancer: a dynamic process? Clin. Cancer Res. (2004) 10:4742-4745.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 4742-4745
-
-
Carles, J.1
Lloreta, J.2
Salido, M.3
-
127
-
-
0030978334
-
Prognostic significance of HER-2/neu gene amplification status by fluorescence in situ hybridization of prostate carcinoma
-
ROSS JS, SHEEHAN CE, HAYNER-BUCHAN AM et al.: Prognostic significance of HER-2/neu gene amplification status by fluorescence in situ hybridization of prostate carcinoma. Cancer (1997) 79:2162-2170.
-
(1997)
Cancer
, vol.79
, pp. 2162-2170
-
-
Ross, J.S.1
Sheehan, C.E.2
Hayner-Buchan, A.M.3
-
128
-
-
0036159186
-
Her-2/neu oncogene amplification in clinically localised prostate cancer
-
OXLEY JD, WINKLER MH, GILLATT DA, PEAT DS: Her-2/neu oncogene amplification in clinically localised prostate cancer. J. Clin. Pathol. (2002) 55:118-120.
-
(2002)
J. Clin. Pathol.
, vol.55
, pp. 118-120
-
-
Oxley, J.D.1
Winkler, M.H.2
Gillatt, D.A.3
Peat, D.S.4
-
129
-
-
0036142778
-
Expression and gene copy number analysis of ERBB2 oncogene in prostate cancer
-
SAVINAINEN KJ, SARAMAKI OR, LINJA MJ et al.: Expression and gene copy number analysis of ERBB2 oncogene in prostate cancer. Am. J. Pathol. (2002) 160:339-345.
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 339-345
-
-
Savinainen, K.J.1
Saramaki, O.R.2
Linja, M.J.3
-
130
-
-
0032850677
-
Multinational Study of the Efficacy and Safety of Humanized Anti-HER2 Monoclonal Antibody in Women Who Have HER2-Overexpressing Metastatic Breast Cancer That Has Progressed After Chemotherapy for Metastatic Disease
-
COBLEIGH MA, VOGEL CL, TRIPATHY D et al.: Multinational Study of the Efficacy and Safety of Humanized Anti-HER2 Monoclonal Antibody in Women Who Have HER2-Overexpressing Metastatic Breast Cancer That Has Progressed After Chemotherapy for Metastatic Disease. J. Clin. Oncol. (1999) 17:2639.
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 2639
-
-
Cobleigh, M.A.1
Vogel, C.L.2
Tripathy, D.3
-
131
-
-
0037083383
-
HER-2 profiling and targeting in prostate carcinoma
-
MORRIS MJ, REUTER VE, KELLY WK et al.: HER-2 profiling and targeting in prostate carcinoma. Cancer (2002) 94:980-986.
-
(2002)
Cancer
, vol.94
, pp. 980-986
-
-
Morris, M.J.1
Reuter, V.E.2
Kelly, W.K.3
-
132
-
-
2342456382
-
Trastuzumab plus docetaxel in HER-2/neu-positive prostate carcinoma: Final results from the California Cancer Consortium Screening and Phase II Trial
-
LARA PN, JR., CHEE KG, LONGMATE J et al.: Trastuzumab plus docetaxel in HER-2/neu-positive prostate carcinoma: final results from the California Cancer Consortium Screening and Phase II Trial. Cancer (2004) 100:2125-2131.
-
(2004)
Cancer
, vol.100
, pp. 2125-2131
-
-
Lara Jr., P.N.1
Chee, K.G.2
Longmate, J.3
-
133
-
-
3943104783
-
The use of trastuzumab in the treatment of hormone refractory prostate cancer; Phase II trial
-
ZIADA A, BARQAWI A, GLODE LM et al.: The use of trastuzumab in the treatment of hormone refractory prostate cancer; Phase II trial. Prostate (2004) 60:332-337.
-
(2004)
Prostate
, vol.60
, pp. 332-337
-
-
Ziada, A.1
Barqawi, A.2
Glode, L.M.3
-
134
-
-
0034784680
-
Docetaxel, estramustine, plus trastuzumab in patients with metastatic androgen-independent prostate cancer
-
SMALL EJ, BOK R, REESE DM, SUDILOVSKY D, FROHLICH M: Docetaxel, estramustine, plus trastuzumab in patients with metastatic androgen-independent prostate cancer. Semin. Oncol. (2001) 28:71-76.
-
(2001)
Semin. Oncol.
, vol.28
, pp. 71-76
-
-
Small, E.J.1
Bok, R.2
Reese, D.M.3
Sudilovsky, D.4
Frohlich, M.5
-
135
-
-
0032482369
-
PTEN/MMAC1/TEP1 involvement in primary prostate cancers
-
PESCHE S, LATIL A, MUZEAU F et al.: PTEN/MMAC1/TEP1 involvement in primary prostate cancers. Oncogene (1998) 16:2879-2883.
-
(1998)
Oncogene
, vol.16
, pp. 2879-2883
-
-
Pesche, S.1
Latil, A.2
Muzeau, F.3
-
136
-
-
5144226211
-
PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
-
NAGATA Y, LAN KH, ZHOU X et al.: PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell (2004) 6:117-127.
-
(2004)
Cancer Cell
, vol.6
, pp. 117-127
-
-
Nagata, Y.1
Lan, K.H.2
Zhou, X.3
-
137
-
-
1842605531
-
Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex
-
FRANKLIN MC, CAREY KD, VAJDOS FF et al.: Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex. Cancer Cell (2004) 5:317-328.
-
(2004)
Cancer Cell
, vol.5
, pp. 317-328
-
-
Franklin, M.C.1
Carey, K.D.2
Vajdos, F.F.3
-
138
-
-
19044380618
-
Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth
-
AGUS DB, AKITA RW, FOX WD et al.: Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth. Cancer Cell (2002) 2:127-137.
-
(2002)
Cancer Cell
, vol.2
, pp. 127-137
-
-
Agus, D.B.1
Akita, R.W.2
Fox, W.D.3
-
139
-
-
0347511057
-
Clinical activity in a Phase I trial of HER-2-targeted rhuMAb 2C4 (pertuzumab) in patients with advanced solid malignancies (AST)
-
(Abstract)
-
AGUS DB, GORDON M, TAYLOR C et al. Clinical activity in a Phase I trial of HER-2-targeted rhuMAb 2C4 (pertuzumab) in patients with advanced solid malignancies (AST). Proc. Am. Soc. Clin. Oncol. (2003) 22:92 (Abstract).
-
(2003)
Proc. Am. Soc. Clin. Oncol.
, vol.22
, pp. 92
-
-
Agus, D.B.1
Gordon, M.2
Taylor, C.3
-
140
-
-
0036842170
-
Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types
-
BASELGA J, RISCHIN D, RANSON M et al.: Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types. J. Clin. Oncol. (2002) 20:4292-4302.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 4292-4302
-
-
Baselga, J.1
Rischin, D.2
Ranson, M.3
-
141
-
-
5644241144
-
Gefitinib ('IRESSA', ZD1839) inhibits EGF-induced invasion in prostate cancer cells by suppressing PI3 K/AKT activation
-
BONACCORSI L, MARCHIANI S, MURATORI M, FORTI G, BALDI E: Gefitinib ('IRESSA', ZD1839) inhibits EGF-induced invasion in prostate cancer cells by suppressing PI3 K/AKT activation. J. Cancer Res. Clin. Oncol. (2004) 130:604-614.
-
(2004)
J. Cancer Res. Clin. Oncol.
, vol.130
, pp. 604-614
-
-
Bonaccorsi, L.1
Marchiani, S.2
Muratori, M.3
Forti, G.4
Baldi, E.5
-
142
-
-
0036899978
-
Studies with CWR22 Xenografts in Nude Mice Suggest That ZD1839 May Have a Role in the Treatment of Both Androgen-dependent and Androgen-independent Human Prostate Cancer
-
SIROTNAK FM, SHE Y, LEE F, CHEN J, SCHER HI: Studies with CWR22 Xenografts in Nude Mice Suggest That ZD1839 May Have a Role in the Treatment of Both Androgen-dependent and Androgen-independent Human Prostate Cancer. Clin. Cancer Res. (2002) 8:3870-3876.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 3870-3876
-
-
Sirotnak, F.M.1
She, Y.2
Lee, F.3
Chen, J.4
Scher, H.I.5
-
143
-
-
0034909841
-
Growth factors and their receptors: New targets for prostate cancer therapy
-
BARTON J, BLACKLEDGE G, WAKELING A: Growth factors and their receptors: new targets for prostate cancer therapy. Urology (2001) 58:114-122.
-
(2001)
Urology
, vol.58
, pp. 114-122
-
-
Barton, J.1
Blackledge, G.2
Wakeling, A.3
-
144
-
-
85047696958
-
ZD1839 ('Iressa'), a specific oral epidermal growth factor receptor-tyrosine kinase inhibitor, potentiates radiotherapy in a human colorecral cancer xenograft model
-
WILLIAMS KJ, TELFER BA, STRATFORD IJ, WEDGE SR: ZD1839 ('Iressa'), a specific oral epidermal growth factor receptor-tyrosine kinase inhibitor, potentiates radiotherapy in a human colorecral cancer xenograft model. Br. J. Cancer (2002) 86:1157-1161.
-
(2002)
Br. J. Cancer
, vol.86
, pp. 1157-1161
-
-
Williams, K.J.1
Telfer, B.A.2
Stratford, I.J.3
Wedge, S.R.4
-
145
-
-
3442891161
-
Dual-Agent Molecular Targeting of the Epidermal Growth Factor Receptor (EGFR): Combining Anti-EGFR Antibody with Tyrosine Kinase Inhibitor
-
HUANG S, ARMSTRONG EA, BENAVENTE S, CHINNAIYAN P, HARARI PM: Dual-Agent Molecular Targeting of the Epidermal Growth Factor Receptor (EGFR): Combining Anti-EGFR Antibody with Tyrosine Kinase Inhibitor. Cancer Res. (2004) 64:5355-5362.
-
(2004)
Cancer Res.
, vol.64
, pp. 5355-5362
-
-
Huang, S.1
Armstrong, E.A.2
Benavente, S.3
Chinnaiyan, P.4
Harari, P.M.5
-
146
-
-
3242675012
-
Combined targeting of epidermal growth factor receptor and MDM2 by gefitinib and antisense MDM2 cooperatively inhibit hormone-independent prostate cancer
-
BIANCO R, CAPUTO R, CAPUTO R et al.: Combined targeting of epidermal growth factor receptor and MDM2 by gefitinib and antisense MDM2 cooperatively inhibit hormone-independent prostate cancer. Clin. Cancer Res. (2004) 10:4858-4864.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 4858-4864
-
-
Bianco, R.1
Caputo, R.2
Caputo, R.3
-
147
-
-
0030774045
-
Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase
-
MOYER JD, BARBACCI EG, IWATA KK et al.: Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res. (1997) 57:4838-4848.
-
(1997)
Cancer Res.
, vol.57
, pp. 4838-4848
-
-
Moyer, J.D.1
Barbacci, E.G.2
Iwata, K.K.3
-
148
-
-
19944426270
-
A Phase II trial of imatinib mesylate in patients with prostate specific antigen progression after local therapy for prostate cancer
-
RAO K, GOODIN S, LEVITT MJ et al.: A Phase II trial of imatinib mesylate in patients with prostate specific antigen progression after local therapy for prostate cancer. Prostate (2005) 62:115-122.
-
(2005)
Prostate
, vol.62
, pp. 115-122
-
-
Rao, K.1
Goodin, S.2
Levitt, M.J.3
-
149
-
-
2342565080
-
Imatinib mesylate and zoledronic acid in androgen-independent prostate cancer
-
TIFFANY NM, WERSINGER EM, GARZOTTO M, BEER TM: Imatinib mesylate and zoledronic acid in androgen-independent prostate cancer. Urology (2004) 63:934-939.
-
(2004)
Urology
, vol.63
, pp. 934-939
-
-
Tiffany, N.M.1
Wersinger, E.M.2
Garzotto, M.3
Beer, T.M.4
-
150
-
-
4344717475
-
Platelet-derived growth factor receptor inhibitor imatinib mesylate and docetaxel: A modular Phase I trial in androgen-independent prostate cancer
-
MATHEW P, THALL PF, JONES D et al.: Platelet-derived growth factor receptor inhibitor imatinib mesylate and docetaxel: a modular Phase I trial in androgen-independent prostate cancer. J. Clin. Oncol. (2004) 22:3323-3329.
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 3323-3329
-
-
Mathew, P.1
Thall, P.F.2
Jones, D.3
-
151
-
-
17944377486
-
Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR
-
NESHAT MS, MELLINGHOFF IK, TRAN C et al.: Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR. Proc. Natl. Acad. Sci. USA (2001) 98:10314-10319.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 10314-10319
-
-
Neshat, M.S.1
Mellinghoff, I.K.2
Tran, C.3
-
152
-
-
0036830256
-
Inhibitors of mTOR Reverse Doxorubicin Resistance Conferred by PTEN Status in Prostate Cancer Cells
-
GRUNWALD V, DEGRAFFENRIED L, RUSSEL D et al.: Inhibitors of mTOR Reverse Doxorubicin Resistance Conferred by PTEN Status in Prostate Cancer Cells. Cancer Res. (2002) 62:6141-6145.
-
(2002)
Cancer Res.
, vol.62
, pp. 6141-6145
-
-
Grunwald, V.1
Degraffenried, L.2
Russel, D.3
-
153
-
-
2942724235
-
mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways
-
MAJUMDER PK, FEBBO PG, BIKOFF R et al.: mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways. Nat. Med. (2004) 10:594-601.
-
(2004)
Nat. Med.
, vol.10
, pp. 594-601
-
-
Majumder, P.K.1
Febbo, P.G.2
Bikoff, R.3
-
154
-
-
3242670740
-
Expression of bFGF, VEGF and c-met and their correlation with microvessel density and progression in prostate carcinoma
-
STROHMEYER D, STRAUSS F, ROSSING C et al.: Expression of bFGF, VEGF and c-met and their correlation with microvessel density and progression in prostate carcinoma. Anti-Cancer Res. (2004) 24:1797-1804.
-
(2004)
Anti-Cancer Res.
, vol.24
, pp. 1797-1804
-
-
Strohmeyer, D.1
Strauss, F.2
Rossing, C.3
-
155
-
-
3142704316
-
Expression of pro-angiogenic growth factors VEGF, EGF and bFGF and their topographical relation to neovascularisation in prostate cancer
-
TROJAN L, THOMAS D, KNOLL T et al.: Expression of pro-angiogenic growth factors VEGF, EGF and bFGF and their topographical relation to neovascularisation in prostate cancer. Urol. Res. (2004) 32:97-103.
-
(2004)
Urol. Res.
, vol.32
, pp. 97-103
-
-
Trojan, L.1
Thomas, D.2
Knoll, T.3
-
156
-
-
0033866725
-
Inhibition of growth and regulation of IGFs and VEGF in human prostate cancer cell lines by shikonin analogue 93/637 (SA)
-
GADDIPATI JP, MANI H, SHEFALI et al.: Inhibition of growth and regulation of IGFs and VEGF in human prostate cancer cell lines by shikonin analogue 93/637 (SA). Anti-Cancer Res. (2000) 20:2547-2552.
-
(2000)
Anti-Cancer Res.
, vol.20
, pp. 2547-2552
-
-
Gaddipati, J.P.1
Mani, H.2
Shefali3
-
157
-
-
0347356345
-
Neutralizing VEGF bioactivity with a soluble chimeric VEGF-receptor protein flt(1-3)IgG inhibits testosterone-stimulated prostate growth in castrated mice
-
LISSBRANT IF, HAMMARSTEN P, LISSBRANT E et al.: Neutralizing VEGF bioactivity with a soluble chimeric VEGF-receptor protein flt(1-3)IgG inhibits testosterone-stimulated prostate growth in castrated mice. Prostate (2004) 58:57-65.
-
(2004)
Prostate
, vol.58
, pp. 57-65
-
-
Lissbrant, I.F.1
Hammarsten, P.2
Lissbrant, E.3
-
158
-
-
0034772250
-
Prognostic Significance of Plasma Vascular Endothelial Growth Factor Levels in Patients with Hormone-refractory Prostate Cancer Treated on Cancer and Leukemia Group B 9480
-
GEORGE DJ, HALABI S, SHEPARD TF et al.: Prognostic Significance of Plasma Vascular Endothelial Growth Factor Levels in Patients with Hormone-refractory Prostate Cancer Treated on Cancer and Leukemia Group B 9480. Clin. Cancer Res. (2001) 7:1932-1936.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 1932-1936
-
-
George, D.J.1
Halabi, S.2
Shepard, T.F.3
-
159
-
-
2442641793
-
Association of Preoperative Plasma Levels of Vascular Endothelial Growth Factor and Soluble Vascular Cell Adhesion Molecule-1 With Lymph Node Status and Biochemical Progression After Radical Prostatectomy
-
SHARIAT SF, ANWURI VA, LAMB DJ et al.: Association of Preoperative Plasma Levels of Vascular Endothelial Growth Factor and Soluble Vascular Cell Adhesion Molecule-1 With Lymph Node Status and Biochemical Progression After Radical Prostatectomy. J. Clin. Oncol. (2004) 22:1655-1663.
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 1655-1663
-
-
Shariat, S.F.1
Anwuri, V.A.2
Lamb, D.J.3
-
160
-
-
0035866781
-
Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor Urine Levels as Predictors of Outcome in Hormone-refractory Prostate Cancer Patients: A Cancer and Leukemia Group B Study
-
BOK RA, HALABI S, FEI DT et al.: Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor Urine Levels as Predictors of Outcome in Hormone-refractory Prostate Cancer Patients: A Cancer and Leukemia Group B Study. Cancer Res. (2001) 61:2533-2536.
-
(2001)
Cancer Res.
, vol.61
, pp. 2533-2536
-
-
Bok, R.A.1
Halabi, S.2
Fei, D.T.3
-
161
-
-
2542421792
-
A Randomized Phase II Trial of the Antiangiogenic Agent SU5416 in Hormone-Refractory Prostate Cancer
-
STADLER WM, CAO D, VOGELZANG NJ et al.: A Randomized Phase II Trial of the Antiangiogenic Agent SU5416 in Hormone-Refractory Prostate Cancer. Clin. Cancer Res. (2004) 10:3365-3370.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 3365-3370
-
-
Stadler, W.M.1
Cao, D.2
Vogelzang, N.J.3
-
162
-
-
0041508658
-
G protein-coupled receptors provide survival signals in prostate cancer
-
YOWELL CW, DAAKA Y: G protein-coupled receptors provide survival signals in prostate cancer. Clin. Prostate Cancer (2002) 1:177-181.
-
(2002)
Clin. Prostate Cancer
, vol.1
, pp. 177-181
-
-
Yowell, C.W.1
Daaka, Y.2
-
163
-
-
0035868342
-
Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN
-
PIANETTI S, ARSURA M, ROMIEU-MOUREZ R, COFFEY RJ, SONENSHEIN GE: Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN. Oncogene (2001) 20:1287-1299.
-
(2001)
Oncogene
, vol.20
, pp. 1287-1299
-
-
Pianetti, S.1
Arsura, M.2
Romieu-Mourez, R.3
Coffey, R.J.4
Sonenshein, G.E.5
-
164
-
-
0036196320
-
NF-kappa B activates prostate-specific antigen expression and is upregulated in androgen-independent prostate cancer
-
CHEN CD, SAWYERS CL: NF-kappa B activates prostate-specific antigen expression and is upregulated in androgen-independent prostate cancer. Mol. Cell Biol. (2002) 22:2862-2870.
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 2862-2870
-
-
Chen, C.D.1
Sawyers, C.L.2
-
165
-
-
3242798367
-
NF-kappaB activation in human prostate cancer: Important mediator or epiphenomenon?
-
SUH J, RABSON AB: NF-kappaB activation in human prostate cancer: important mediator or epiphenomenon? J. Cell. Biochem. (2004) 91:100-117.
-
(2004)
J. Cell Biochem.
, vol.91
, pp. 100-117
-
-
Suh, J.1
Rabson, A.B.2
-
166
-
-
0037351342
-
NF-kappa B nuclear localization and its prognostic significance in prostate cancer
-
LESSARD L, MES-MASSON AM, LAMARRE L et al.: NF-kappa B nuclear localization and its prognostic significance in prostate cancer. BJU Int. (2003) 91:417-420.
-
(2003)
BJU Int.
, vol.91
, pp. 417-420
-
-
Lessard, L.1
Mes-Masson, A.M.2
Lamarre, L.3
-
167
-
-
3442882798
-
Bortezomib as a Potential Treatment for Prostate Cancer
-
PAPANDREOU CN, LOGOTHETIS CJ: Bortezomib as a Potential Treatment for Prostate Cancer. Cancer Res. (2004) 64:5036-5043.
-
(2004)
Cancer Res.
, vol.64
, pp. 5036-5043
-
-
Papandreou, C.N.1
Logothetis, C.J.2
-
168
-
-
0035069305
-
Interleukin-6 and prostate cancer progression
-
SMITH PC, HOBISCH A, LIN DL, CULIG Z, KELLER ET: Interleukin-6 and prostate cancer progression. Cytokine Growth Factor Rev. (2001) 12:33-40.
-
(2001)
Cytokine Growth Factor Rev.
, vol.12
, pp. 33-40
-
-
Smith, P.C.1
Hobisch, A.2
Lin, D.L.3
Culig, Z.4
Keller, E.T.5
-
169
-
-
0037195503
-
Interleukin-6 regulates androgen receptor activity and prostate cancer cell growth
-
CULIG Z, BARTSCH G, HOBISCH A: Interleukin-6 regulates androgen receptor activity and prostate cancer cell growth. Mol. Cell Endocrinol. (2002) 197:231-238.
-
(2002)
Mol. Cell. Endocrinol.
, vol.197
, pp. 231-238
-
-
Culig, Z.1
Bartsch, G.2
Hobisch, A.3
-
170
-
-
5044237617
-
Serum levels of IL-6 and TNF-alpha correlate with clinicopathological features and patient survival in patients with prostate cancer
-
MICHALAKI V, SYRIGOS K, CHARLES P, WAXMAN J: Serum levels of IL-6 and TNF-alpha correlate with clinicopathological features and patient survival in patients with prostate cancer. Br. J. Cancer (2004) 91:1227.
-
(2004)
Br. J. Cancer
, vol.91
, pp. 1227
-
-
Michalaki, V.1
Syrigos, K.2
Charles, P.3
Waxman, J.4
-
171
-
-
0029116310
-
Endothelins
-
LEVIN ER: Endothelins. N. Engl. J. Med. (1995) 333:356-363.
-
(1995)
N. Engl. J. Med.
, vol.333
, pp. 356-363
-
-
Levin, E.R.1
-
172
-
-
0027179084
-
Endothelin-1 in the human prostate: Tissue levels, source of production and isometric tension studies
-
LANGENSTROER P, TANG R, SHAPIRO E et al.: Endothelin-1 in the human prostate: tissue levels, source of production and isometric tension studies. J. Urol. (1993) 150:495-499.
-
(1993)
J. Urol.
, vol.150
, pp. 495-499
-
-
Langenstroer, P.1
Tang, R.2
Shapiro, E.3
-
173
-
-
0029085123
-
Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate
-
NELSON JB, HEDICAN SP, GEORGE DJ et al.: Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate. Nat. Med. (1995) 1:944-949.
-
(1995)
Nat. Med.
, vol.1
, pp. 944-949
-
-
Nelson, J.B.1
Hedican, S.P.2
George, D.J.3
-
174
-
-
0141479984
-
A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases
-
YIN JJ, MOHAMMAD KS, KAKONEN SM et al.: A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases. Proc. Natl. Acad. Sci. USA (2003) 100:10954-10959.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 10954-10959
-
-
Yin, J.J.1
Mohammad, K.S.2
Kakonen, S.M.3
-
175
-
-
0037089676
-
Atrasentan, an endothelin-receptor antagonist for refractory adenocarcinomas: Safety and pharmacokinetics
-
CARDUCCI MA, NELSON JB, BOWLING MK et al.: Atrasentan, an endothelin-receptor antagonist for refractory adenocarcinomas: safety and pharmacokinetics. J. Clin. Oncol. (2002) 20:2171-2180.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 2171-2180
-
-
Carducci, M.A.1
Nelson, J.B.2
Bowling, M.K.3
-
176
-
-
0041464540
-
Phase I dose-escalation study of the safety and pharmacokinetics of atrasentan: An endothelin receptor antagonist for refractory prostate cancer
-
ZONNENBERG BA, GROENEWEGEN G, JANUS TJ et al.: Phase I dose-escalation study of the safety and pharmacokinetics of atrasentan: an endothelin receptor antagonist for refractory prostate cancer. Clin. Cancer Res. (2003) 9:2965-2972.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 2965-2972
-
-
Zonnenberg, B.A.1
Groenewegen, G.2
Janus, T.J.3
-
177
-
-
0037441843
-
Effect of endothelin-A receptor blockade with atrasentan on tumor progression in men with hormone-refractory prostate cancer: A randomized, Phase II, placebo-controlled trial
-
CARDUCCI MA, PADLEY RJ, BREUL J et al.: Effect of endothelin-A receptor blockade with atrasentan on tumor progression in men with hormone-refractory prostate cancer: a randomized, Phase II, placebo-controlled trial. J. Clin. Oncol. (2003) 21:679-689.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 679-689
-
-
Carducci, M.A.1
Padley, R.J.2
Breul, J.3
-
178
-
-
4444328753
-
Superiority of YM598 over atrasentan as a selective endothelin ET(A) receptor antagonist
-
YUYAMA H, NOGUCHI Y, FUJIMORI A et al.: Superiority of YM598 over atrasentan as a selective endothelin ET(A) receptor antagonist. Eur. J. Pharmacol. (2004) 498:171-177.
-
(2004)
Eur. J. Pharmacol.
, vol.498
, pp. 171-177
-
-
Yuyama, H.1
Noguchi, Y.2
Fujimori, A.3
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