메뉴 건너뛰기




Volumn 5, Issue 3, 1999, Pages 280-285

A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; ONCOPROTEIN; PROSTATE SPECIFIC ANTIGEN; PROTEIN TYROSINE KINASE;

EID: 0033022342     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/6495     Document Type: Article
Times cited : (864)

References (45)
  • 1
    • 0029011116 scopus 로고
    • Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer
    • Talpin, M.E. et al. Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer. N. Engl. J. Med. 332, 1393-1398 (1995).
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1393-1398
    • Talpin, M.E.1
  • 2
    • 0028278076 scopus 로고
    • Frequent detection of codon 877 mutation in the androgen receptor gene in advanced prostate cancers
    • Gaddipati, J.P. et al. Frequent detection of codon 877 mutation in the androgen receptor gene in advanced prostate cancers. Cancer Res. 54, 2861-2864 (1994).
    • (1994) Cancer Res. , vol.54 , pp. 2861-2864
    • Gaddipati, J.P.1
  • 3
    • 0028944138 scopus 로고
    • In vivo amplification of the androgen receptor gene and progression of human prostate cancer
    • Visakorpi, T. et al. In vivo amplification of the androgen receptor gene and progression of human prostate cancer. Nature Genet. 9, 401-406 (1995).
    • (1995) Nature Genet. , vol.9 , pp. 401-406
    • Visakorpi, T.1
  • 4
    • 0026562430 scopus 로고
    • The androgen receptor in LNCaP cells contains a mutation in the ligand binding domain which affects steroid binding characteristics and response to antiandrogens
    • Veldscholte, J. et al. The androgen receptor in LNCaP cells contains a mutation in the ligand binding domain which affects steroid binding characteristics and response to antiandrogens. J. Steroid Biochem. Mol. Biol. 41, 665-669 (1992).
    • (1992) J. Steroid Biochem. Mol. Biol. , vol.41 , pp. 665-669
    • Veldscholte, J.1
  • 5
    • 0026556306 scopus 로고
    • Coupling of dual signaling pathways: Epidermal growth factor action involves the estrogen receptor
    • Ignar-Trowbridge, D.M. et al. Coupling of dual signaling pathways: epidermal growth factor action involves the estrogen receptor. Proc. Natl. Acad. Sci. USA 89, 4658-4662 (1992).
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4658-4662
    • Ignar-Trowbridge, D.M.1
  • 6
    • 0026317212 scopus 로고
    • Dopaminergic and ligand-independent activation of steroid hormone receptors
    • Power, R.F., Mani, S.K., Codina, J., Conneely, O.M. & O'Malley, B.W. Dopaminergic and ligand-independent activation of steroid hormone receptors. Science 254, 1636-1639 (1991).
    • (1991) Science , vol.254 , pp. 1636-1639
    • Power, R.F.1    Mani, S.K.2    Codina, J.3    Conneely, O.M.4    O'Malley, B.W.5
  • 7
    • 0027302009 scopus 로고
    • Stimulation of estrogen receptor-mediated transcription and alteration in the phosphorylation state of the rat uterine estrogen receptor by estrogen, cyclic adenosine monophosphate, and insulin-like growth factor-1
    • Aronica, S.M. & Katzenellenbogen, B.S. Stimulation of estrogen receptor-mediated transcription and alteration in the phosphorylation state of the rat uterine estrogen receptor by estrogen, cyclic adenosine monophosphate, and insulin-like growth factor-1. Mol. Endocrinol. 7, 743-752 (1993).
    • (1993) Mol. Endocrinol. , vol.7 , pp. 743-752
    • Aronica, S.M.1    Katzenellenbogen, B.S.2
  • 8
    • 0025697567 scopus 로고
    • Regulation of progesterone receptor-mediated transcription by phosphorylation
    • Denner, L.A., Weigel, N.L., Maxwell, B.L., Schrader, W.T., & O'Malley, B.W. Regulation of progesterone receptor-mediated transcription by phosphorylation. Science 250, 1740-1743 (1990).
    • (1990) Science , vol.250 , pp. 1740-1743
    • Denner, L.A.1    Weigel, N.L.2    Maxwell, B.L.3    Schrader, W.T.4    O'Malley, B.W.5
  • 9
    • 0028886694 scopus 로고
    • Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase
    • Kato, S. et al. Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science 270, 1491-1494 (1995).
    • (1995) Science , vol.270 , pp. 1491-1494
    • Kato, S.1
  • 10
    • 0028113415 scopus 로고
    • Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-1, keratinocyte growth factor, and epiderman growth factor
    • Culig, Z. et al. Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-1, keratinocyte growth factor, and epiderman growth factor. Cancer Res. 54, 5474-5478 (1994).
    • (1994) Cancer Res. , vol.54 , pp. 5474-5478
    • Culig, Z.1
  • 11
    • 0024337144 scopus 로고
    • Studies of the Her-2/neu proto-oncogene in human breast and ovarian cancer
    • Slamon, D.J. et al. Studies of the Her-2/neu proto-oncogene in human breast and ovarian cancer. Science 244, 707-712 (1989).
    • (1989) Science , vol.244 , pp. 707-712
    • Slamon, D.J.1
  • 12
    • 0024449610 scopus 로고
    • Proto-oncogene amplification and human breast tumor phenotype
    • Adnane, J. et al. Proto-oncogene amplification and human breast tumor phenotype. Oncogene 4, 1389-1395 (1989).
    • (1989) Oncogene , vol.4 , pp. 1389-1395
    • Adnane, J.1
  • 13
    • 0024507684 scopus 로고
    • HER-2 amplification, steroid receptors and epidermal growth factor receptor in primary breast cancer
    • Zeillinger, R. et al. HER-2 amplification, steroid receptors and epidermal growth factor receptor in primary breast cancer. Oncogene 4, 109-114 (1989).
    • (1989) Oncogene , vol.4 , pp. 109-114
    • Zeillinger, R.1
  • 14
    • 0028360192 scopus 로고
    • ERBB2 amplification is associated with tamoxifen resistance in steroid-receptor positive breast cancer
    • Borg, A. et al. ERBB2 amplification is associated with tamoxifen resistance in steroid-receptor positive breast cancer. Cancer Lett. 81, 137-144 (1994).
    • (1994) Cancer Lett. , vol.81 , pp. 137-144
    • Borg, A.1
  • 15
    • 0029005754 scopus 로고
    • Elevated serum c-erbB-2 antigen levels and decreased response to hormone therapy of breast cancer
    • Leitzel, K. et al. Elevated serum c-erbB-2 antigen levels and decreased response to hormone therapy of breast cancer. J. Clin. Oncol. 13, 1129-1135 (1995).
    • (1995) J. Clin. Oncol. , vol.13 , pp. 1129-1135
    • Leitzel, K.1
  • 16
    • 0028997307 scopus 로고
    • HER-2 tyrosine kinase pathway targets estrogen receptor and promotes hormone-independent growth in human breast cancer cells
    • Pietras, R.J. et al. HER-2 tyrosine kinase pathway targets estrogen receptor and promotes hormone-independent growth in human breast cancer cells. Oncogene 10, 2435-2446 (1995).
    • (1995) Oncogene , vol.10 , pp. 2435-2446
    • Pietras, R.J.1
  • 17
    • 0025974605 scopus 로고
    • Immunohistochemical detection of c-erbB-2 protein in human benign and neoplastic prostate
    • Ware, J.L., Maygarden, S.J., Koontz, W.W. Jr. & Strom, S.C. Immunohistochemical detection of c-erbB-2 protein in human benign and neoplastic prostate. Hum. Pathol. 22, 254-258 (1991).
    • (1991) Hum. Pathol. , vol.22 , pp. 254-258
    • Ware, J.L.1    Maygarden, S.J.2    Koontz W.W., Jr.3    Strom, S.C.4
  • 19
    • 0030933521 scopus 로고    scopus 로고
    • Tissue expression of neu differentiation factor/heregulin and its receptor complex in prostate cancer and its biological effects on prostate cancer cells in vitro
    • Lyne, J.C. et al. Tissue expression of neu differentiation factor/heregulin and its receptor complex in prostate cancer and its biological effects on prostate cancer cells in vitro. Cancer J. Sci. Am. 3, 21-30 (1997).
    • (1997) Cancer J. Sci. Am. , vol.3 , pp. 21-30
    • Lyne, J.C.1
  • 20
    • 0026531267 scopus 로고
    • p53, c-erbB-2 and the epidermal growth factor receptor in the benign and malignant prostate
    • Mellon, K. et al. p53, c-erbB-2 and the epidermal growth factor receptor in the benign and malignant prostate. J. Urol. 147, 496-499 (1992).
    • (1992) J. Urol. , vol.147 , pp. 496-499
    • Mellon, K.1
  • 21
    • 0027748098 scopus 로고
    • Expression of the c-erb-B-2 (HER-2/neu) oncoprotein in human prostatic carcinoma
    • Kuhn, E.J., Kurnot, R.A., Sesterhenn, I.A., Chang, E.H. & Moul, J.W. Expression of the c-erb-B-2 (HER-2/neu) oncoprotein in human prostatic carcinoma. J. Urol. 150, 1427-1433 (1993).
    • (1993) J. Urol. , vol.150 , pp. 1427-1433
    • Kuhn, E.J.1    Kurnot, R.A.2    Sesterhenn, I.A.3    Chang, E.H.4    Moul, J.W.5
  • 22
    • 0027238684 scopus 로고
    • Overexpression of HER-2/Neu may be an indicator of poor prognosis in prostate cancer
    • Sadasivan, R. et al. Overexpression of HER-2/Neu may be an indicator of poor prognosis in prostate cancer. J. Urol. 150, 126-131 (1993).
    • (1993) J. Urol. , vol.150 , pp. 126-131
    • Sadasivan, R.1
  • 23
    • 0030978334 scopus 로고    scopus 로고
    • Prognostic significance of HER-2/neu gene amplification status by fluorescence in situ hybridization of prostate carcinoma
    • Ross, J.S. et al. Prognostic significance of HER-2/neu gene amplification status by fluorescence in situ hybridization of prostate carcinoma. Cancer 79, 2162-2170 (1997).
    • (1997) Cancer , vol.79 , pp. 2162-2170
    • Ross, J.S.1
  • 24
    • 0030888544 scopus 로고    scopus 로고
    • C-erbB-2 oncoprotein: A potential biomarker of advanced prostate cancer
    • Arai, Y., Tatsuhiro, T. & Yoshida, O. C-erbB-2 oncoprotein: a potential biomarker of advanced prostate cancer. Prostate 30, 195-201 (1997).
    • (1997) Prostate , vol.30 , pp. 195-201
    • Arai, Y.1    Tatsuhiro, T.2    Yoshida, O.3
  • 25
    • 16944366096 scopus 로고    scopus 로고
    • Progression of metastatic human prostate cancer to androgen independence in immunodeficient SCID mice
    • Klein, K.A. et al. Progression of metastatic human prostate cancer to androgen independence in immunodeficient SCID mice. Nature Med. 3, 402-408 (1997).
    • (1997) Nature Med. , vol.3 , pp. 402-408
    • Klein, K.A.1
  • 26
    • 0023925702 scopus 로고
    • Application of the MTT assay to human prostate cancer cell lines in vitro: Establishment of test conditions and assessment of hormone-stimulated growth and drug-induced cytostatic and cytotoxic effects
    • Romijn, J.C., Verkoelen, C.F. & Schroeder, F.H. Application of the MTT assay to human prostate cancer cell lines in vitro: establishment of test conditions and assessment of hormone-stimulated growth and drug-induced cytostatic and cytotoxic effects. Prostate 12, 99-110 (1988).
    • (1988) Prostate , vol.12 , pp. 99-110
    • Romijn, J.C.1    Verkoelen, C.F.2    Schroeder, F.H.3
  • 27
    • 0029942883 scopus 로고    scopus 로고
    • CWR22: The first human prostate cancer xenograft with strongly androgen-dependent and relapsed strains both in vivo and in soft agar
    • Nagabhushan, M. et al. CWR22: the first human prostate cancer xenograft with strongly androgen-dependent and relapsed strains both in vivo and in soft agar. Cancer Res. 56, 3042-3046 (1996).
    • (1996) Cancer Res. , vol.56 , pp. 3042-3046
    • Nagabhushan, M.1
  • 28
    • 0025298231 scopus 로고
    • Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation
    • Kyprianou, N., English, HF. & Isaacs, JT. Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation. Cancer Res. 50, 3748-3753 (1990).
    • (1990) Cancer Res. , vol.50 , pp. 3748-3753
    • Kyprianou, N.1    English, H.F.2    Isaacs, J.T.3
  • 29
    • 0026637038 scopus 로고
    • Transcriptional regulation of prostate kallikrein-like genes by androgen
    • Woll, D.A., Schulz, P. & Fittler, F. Transcriptional regulation of prostate kallikrein-like genes by androgen. Mol. Endocrinol. 6, 753-762 (1992).
    • (1992) Mol. Endocrinol. , vol.6 , pp. 753-762
    • Woll, D.A.1    Schulz, P.2    Fittler, F.3
  • 30
    • 0031017102 scopus 로고    scopus 로고
    • An androgen response element in a far upstream enhancer region is essential for high, androgen-regulated activity of the prostate-specific antigen promoter
    • Cleutjens, K.B.J.M. et al. An androgen response element in a far upstream enhancer region is essential for high, androgen-regulated activity of the prostate-specific antigen promoter. Mol. Endocrinol. 11, 148-161 (1997).
    • (1997) Mol. Endocrinol. , vol.11 , pp. 148-161
    • Cleutjens, K.B.J.M.1
  • 31
    • 0029924175 scopus 로고    scopus 로고
    • Prostate-specific antigen expression is regulated by an upstream enhancer
    • Schurr, E.R. et al. Prostate-specific antigen expression is regulated by an upstream enhancer. J. Biol. Chem. 271, 7043-7051 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 7043-7051
    • Schurr, E.R.1
  • 32
    • 0031059178 scopus 로고    scopus 로고
    • Identification of a positive regulatory element responsible for tissue-specific expression of prostate-specific antigen
    • Pang, S. et al. Identification of a positive regulatory element responsible for tissue-specific expression of prostate-specific antigen. Cancer Res. 57, 495-499 (1997).
    • (1997) Cancer Res. , vol.57 , pp. 495-499
    • Pang, S.1
  • 33
    • 0030612007 scopus 로고    scopus 로고
    • TAFII250-dependent transcription of cyclin A is directed by ATF activator proteins
    • Wang, E.H., Zou, S. & Tjian, R. TAFII250-dependent transcription of cyclin A is directed by ATF activator proteins. Genes Dev. 11, 2658-2669 (1997).
    • (1997) Genes Dev. , vol.11 , pp. 2658-2669
    • Wang, E.H.1    Zou, S.2    Tjian, R.3
  • 35
    • 0032559272 scopus 로고    scopus 로고
    • Plasma insulin-like growth factor-1 and prostate cancer risk: A prospective study
    • Chan, J.M. et al. Plasma insulin-like growth factor-1 and prostate cancer risk: a prospective study. Science 279, 563-566 (1998).
    • (1998) Science , vol.279 , pp. 563-566
    • Chan, J.M.1
  • 36
    • 0029937307 scopus 로고    scopus 로고
    • Antisense RNA to the type 1 insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cell in vivo
    • Burfeind, P., Chernicky, C.L., Rininsland, F. & Ilan, J. Antisense RNA to the type 1 insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cell in vivo. Proc. Natl. Acad. Sci. USA 93, 7263-7268 (1996).
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7263-7268
    • Burfeind, P.1    Chernicky, C.L.2    Rininsland, F.3    Ilan, J.4
  • 37
    • 0028229715 scopus 로고
    • A single autophosphorylation site confers oncogenicity to the Neu/ErbB-2 receptor and enables coupling to the MAP kinase pathway
    • Ben-Levy, R., Paterson, H.F., Marshall, C.J. & Yarden, Y. A single autophosphorylation site confers oncogenicity to the Neu/ErbB-2 receptor and enables coupling to the MAP kinase pathway. EMBO J. 13, 3302-3311 (1994).
    • (1994) EMBO J. , vol.13 , pp. 3302-3311
    • Ben-Levy, R.1    Paterson, H.F.2    Marshall, C.J.3    Yarden, Y.4
  • 38
    • 0029877913 scopus 로고    scopus 로고
    • Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation
    • Bunone, C., Briand, P.-A., Miksicek, R.J. & Picard, D. Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation. EMBO J. 15, 2174-2183 (1996).
    • (1996) EMBO J. , vol.15 , pp. 2174-2183
    • Bunone, C.1    Briand, P.-A.2    Miksicek, R.J.3    Picard, D.4
  • 39
    • 0030570961 scopus 로고    scopus 로고
    • A growing coactivator network
    • Janknecht, R. & Hunter, T. A growing coactivator network. Nature 383, 22-23 (1996).
    • (1996) Nature , vol.383 , pp. 22-23
    • Janknecht, R.1    Hunter, T.2
  • 41
    • 0000905158 scopus 로고    scopus 로고
    • +a (humanized anti-HER2 antibody) as a single agent in 222 women with HER2 overexpression who relapsed following chemotherapy for metastatic breast cancer
    • +a (humanized anti-HER2 antibody) as a single agent in 222 women with HER2 overexpression who relapsed following chemotherapy for metastatic breast cancer. Progr/Proc. Am. Soc. Clin. Oncol. 17, 97a (1998).
    • (1998) Progr/Proc. Am. Soc. Clin. Oncol. , vol.17
    • Cobleigh, M.A.1
  • 42
    • 0000405942 scopus 로고    scopus 로고
    • Addition of Herceptin (humanized anti-HER2 antibody) to first line chemotherapy for HER2 overexpressing metastatic breast cancer (HER2+/MBC) markedly increases anticancer activity: A randomized, multinational controlled phase III trial
    • Slamon, D. et al. Addition of Herceptin (humanized anti-HER2 antibody) to first line chemotherapy for HER2 overexpressing metastatic breast cancer (HER2+/MBC) markedly increases anticancer activity: a randomized, multinational controlled phase III trial. Progr/Proc. Am. Soc. Clin. Oncol. 17, 98a (1998).
    • (1998) Progr/Proc. Am. Soc. Clin. Oncol. , vol.17
    • Slamon, D.1
  • 43
    • 0026739541 scopus 로고
    • Transformation mediated by the human HER-2 gene independent of the epidermal growth factor receptor
    • Chazin, V.R., Kaleko, M., Miller, A.D. & Slamon, D.J. Transformation mediated by the human HER-2 gene independent of the epidermal growth factor receptor. Oncogene, 7, 1859-1866 (1992).
    • (1992) Oncogene , vol.7 , pp. 1859-1866
    • Chazin, V.R.1    Kaleko, M.2    Miller, A.D.3    Slamon, D.J.4
  • 44
    • 0027078473 scopus 로고
    • A synergistic increase in potency of a multimerized VP16 transcriptional activation domain
    • Emami, K.H. & Carey, M.A synergistic increase in potency of a multimerized VP16 transcriptional activation domain. EMBO J. 11, 5005-5012 (1992).
    • (1992) EMBO J. , vol.11 , pp. 5005-5012
    • Emami, K.H.1    Carey, M.2
  • 45
    • 0029589929 scopus 로고
    • The Bcr-Abl leukemia oncogene activates Jun Kinase and requires Jun for transformation
    • Raitano, A.B., Halpern, J.R., Hambuch, T.M. & Sawyers, C.L. The Bcr-Abl leukemia oncogene activates Jun Kinase and requires Jun for transformation. Proc. Natl Acad. Sci. USA 92, 11746-50 (1995).
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 11746-11750
    • Raitano, A.B.1    Halpern, J.R.2    Hambuch, T.M.3    Sawyers, C.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.