Identification of ligand-binding regions of P-glycoprotein by activated-pharmacophore photoaffinity labeling and matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry

Molecular Pharmacology

Volumn 61, Issue 3, 2002, Pages 637-648

  Ecker, Gerhard F ^a   Csaszar, Edina ^a   Kopp, Stephan ^a   Plagens, Brigitte ^a   Holzer, Wolfgang ^a   Ernst, Wolfgang ^a   Chiba, Peter ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; AMINO ACID; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; ANTIPARASITIC AGENT; CARBONYL DERIVATIVE; GLYCOPROTEIN P; LIGAND; NUCLEOTIDE BINDING PROTEIN; PROPAFENONE; PROTEIN INHIBITOR;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; DRUG BINDING; ENERGY; HUMAN; HUMAN CELL; LIGAND BINDING; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR WEIGHT; PEROXISOME; PHARMACOPHORE; PHOTOACTIVATION; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; CELL MEMBRANE; HUMANS; LIGANDS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; P-GLYCOPROTEIN; PEPTIDE FRAGMENTS; PHOTOAFFINITY LABELS; RADIOLIGAND ASSAY; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0036176213     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.61.3.637     Document Type: Article

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