Nucleotide-gated KATP channels integrated with creatine and adenylate kinases: Amplification, tuning and sensing of energetic signals in the compartmentalized cellular environment

Molecular and Cellular Biochemistry

Volumn 256-257, Issue 1-2, 2004, Pages 243-256

  Selivanov, Vitaliy A ^a   Alekseev, Alexey E ^a   Hodgson, Denice M ^a   Dzeja, Petras P ^a   Terzic, Andre ^a  

^a MAYO CLINIC   (United States)

Author keywords

ATP sensiitve K+ channel; Heart; Intracellular compartment; Metabolic sensor; Nucleotide diffusion

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENYLATE KINASE; CREATINE KINASE; NUCLEOTIDE; VOLTAGE GATED POTASSIUM CHANNEL; CREATINE; POTASSIUM CHANNEL;

ACTIVE TRANSPORT; ALLOSTERISM; ANIMAL CELL; ARTICLE; CELL COMPARTMENTALIZATION; CELL METABOLISM; CHANNEL GATING; CONTROLLED STUDY; DIFFUSION; ENERGY TRANSFER; ENZYME ACTIVITY; MATHEMATICAL MODEL; NONHUMAN; PHOSPHATE TRANSPORT; RAT; SIGNAL TRANSDUCTION; ANIMAL; CATALYSIS; ENERGY METABOLISM; METABOLISM;

ANIMALIA;

ADENYLATE KINASE; ANIMALS; CATALYSIS; CREATINE; ENERGY METABOLISM; ION CHANNEL GATING; POTASSIUM CHANNELS; SIGNAL TRANSDUCTION;

EID: 0842345396     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/b:mcbi.0000009872.35940.7d     Document Type: Article

References (55)

1. Aliev MK, Saks VA: Compartmentalized energy transfer in cardiomyocytes: Use of mathematical modeling for analysis of in vivo regulation of respiration. Biophys J 73: 428-445, 1997
2. O'Rourke B, Ramza BM, Marban E: Oscillations of membrane current and excitability driven by metabolic oscillations in heart cells. Science 265: 962-966, 1994
3. Ventura-Clapier R, Kuznetsov A, Veksler V, Boehm E, Anflous K: Functional coupling of creatine kinases in muscles: Species and tissue specificity. Mol Cell Biochem 184: 231-247, 1998
4. Hardie DG, Carling D, Carlson M: The AMP-activated/SNF1 protein kinase subfamily: Metabolic sensors of the eukaryotic cell? Annu Rev Biochem 67: 821-855, 1998
5. Janssen E, Dzeja PP, Oerlemans F, Simonetti AW, Heerschap A, de Haan A, Rush PS, Terjung RR, Wieringa B, Terzic A: Adenylate kinase 1 gene deletion disrupts muscle energetic economy despite metabolic rearrangement. EMBO J 19: 6371-6381, 2000
6. Dzeja PP, Redfield MM, Burnett JC, Terzic A: Failing energetics in failing hearts. Curr Cardiol Rep 2: 212-217, 2000
7. ATP: An inward rectifier subunit plus the sulfonylurea receptor. Science 270: 1166-1170, 1995
8. Kaasik A, Veksler V, Boehm E, Novotova M, Minajeva A, Ventura-Clapier R: Energetic crosstalk between organelles: Architectural integration of energy production and utilization. Circ Res 89: 153-159, 2001
9. Saks VA, Kaambre T, Sikk P, Eimre M, Orlova E, Paju K, Piirsoo A, Appaix F, Kay L, Regitz-Zagrosek V, Fleck E, Seppet E: Intracellular energetic units in red muscle cells. Biochem J 356: 643-657, 2001
10. + channel subunits confer resistance to chemical hypoxia-reoxygenation injury. Circulation 98: 1548-1555, 1998
11. Carrasco AJ, Dzeja PP, Alekseev AE, Pucar D, Zingman LV, Abraham MR, Hodgson D, Bienengraeber M, Puceat M, Janssen E, Wieringa B, Terzic A: Adenylate kinase phosphotransfer communicates cellular energetic signals to ATP-sensitive potassium channels. Proc Natl Acad Sci USA 98: 7623-7628, 2001
12. Yamada K, Ji JJ, Yuan H, Miki T, Sato S, Horimoto N, Shimizu T, Seino S, Inagaki N: Protective role of ATP-sensitive potassium channels in hypoxia-induced generalized seizure. Science 292: 1543-1546, 2001
13. + channels. Neuron 16: 1011-1017, 1996
14. + channel subunits Kir6.2 and SUR2A. J Mol Cell Cardiol 31: 425-434, 1999
15. ATP channel subunits. Neuron 18: 827-838, 1997
16. + channels in the absence of the sulphonylurea receptor. Nature 387: 179-183, 1997
17. ATP channel inhibition by ATP requires distinct functional domains of the cytoplasmic C terminus of the pore-forming subunit. Proc Natl Acad Sci USA 95: 13953-13958, 1998
18. ATP channel activity by diazoxide and MgADP: Distinct functions ofthe two nucleotide binding folds of the sulfonylurea receptor. J Gen Physiol 110: 643-654, 1997
19. + channels. Trends Neurosci 21: 288-294, 1998
20. Nichols CG, Shyng SL, Nestorowicz A, Glaser B, Clement JP, Gonzalez G, Aguilar-Bryan L, Permutt MA, Bryan J: Adenosine diphosphate as an intracellular regulator of insulin secretion. Science 272: 1785-1787, 1996
21. Matsuo M, Tanabe K, Kioka N, Amachi T, Ueda K: Different binding properties and affinities for ATP and ADP among suffonylurea receptor subtypes, SUR1, SUR2A, and SUR2B. J Biol Chem 275: 28757-28763, 2000
22. Bienengraeber M, Alekseev AE, Abraham MR, Carrasco AJ, Moreau C, Vivaudou M, Dzeja PP, Terzic A: ATPase activity of the sulfonylurea receptor: A catalytic function for the K-ATP channel complex. FASEB J 14: 1943-1952, 2000
23. + channels. J Biol Chem 277: 14206-14210, 2002
24. + conductance. Neuron 31: 233-245, 2001
25. + channels in isolated membrane patches. J Physiol 419: 193-211, 1989
26. + loss in hypoxic and ischaemic mammalian ventricle. J Physiol 447: 649-673, 1992
27. 31P NMR surface coil studies in brain, heart, and skeletal muscle of the living rat. Biochemistry 26: 6083-6090, 1987
28. Saks VA, Aliev MK: Is there the creatine kinase equilibrium in working heart cells? Biochem Biophys Res Commun 227: 360-367, 1996
29. + channels in isolated guinea pig cardiac myocytes. Science 238: 67-69, 1988
30. + channels. Cardiovasc Drugs Ther 7: 499-505, 1993
31. Lederer WJ, Niggli E, Hadley RW: Sodium-calcium exchange in excitable cells: Fuzzy space. Science 248: 283, 1990
32. + channels. FASEB J 12: 523-529 1998
33. + channels by adenylate kinase activity. J Biol Chem 271: 31903-31908, 1996
34. Abraham MR, Selivanov VA, Hodgson DM, Pucar D, Zingman LV, Wieringa B, Dzeja PP, Alekseev AE, Terzic A: Coupling of cell energetics with membrane metabolic sensing. Integrative signaling through creatine kinase phosphotransfer disrupted by M-CK gene knock-out. J Biol Chem 277: 24427-24434, 2002
35. Dzeja PP, Vitkevicius KT, Redfield MM, Burnett JC, Terzic A: Adenylate kinase-catalyzed phosphotransfer in the myocardium: Increased contribution in heart failure. Circ Res 84: 1137-1143, 1999
36. Olson LK, Schroeder W, Robertson RP, Goldberg ND, Walseth TF: Suppression of adenylate kinase catalyzed phosphotransfer precedes and is associated with glucose-induced insulin secretion in intact HIT-T15 cells. J Biol Chem 271: 16544-16552, 1996
37. ATP channels in cardiac myocytes. Am J Physiol 280: H1882-H1888, 2001
38. + channel in vivo. FASEB J 16: 102-104, 2002
39. + channel activity in intact and permeabilized rat ventricular myocytes. J Physiol 423: 91-110, 1990
40. Chazov EI, Smirnov VN, Saks VA, Rosenshtraukh LV, Lipina NV, Levitsky DO: Energy metabolism and ion fluxes across cardiac membranes. Adv Myocardiol 1: 139-153, 1980
41. ATP channels by Na/K pump in isolated cardiac myocytes and giant membrane patches. Biophys J 75: 2858-2867, 1998
42. Rich TC, Fagan KA, Nakata H, Schaack J, Cooper DM, Karpen JW: Cyclic nucleotide-gated channels colocalize with adenylyl cyclase in regions of restricted cAMP diffusion. J Gen Physiol 116: 147-161, 2000
43. 31P NMR. J Biol Chem 276: 44812-44819, 2001
44. eq of the creatine kinase reaction and other phosphate hydrolyses and phosphate transfer reactions. J Biol Chem 254: 6528-6537, 1979
45. Jacobus WE: Theoretical support for the heart phosphocreatine energy transport shuttle based on the intracellular diffusion limited mobility of ADP. Biochem Biophys Res Commun 133: 1035-1041, 1985
46. Dzeja PP, Zeleznikar RJ, Goldberg ND: Suppression of creatine kinase-catalyzed phosphotransfer results in increased phosphoryl transfer by adenylate kinase in intact skeletal muscle. J Biol Chem 271: 12847-12851, 1996
47. Pucar D, Janssen E, Dzeja PP, Juranic N, Macura S, Wieringa B, Terzic A: Compromised energetics in the adenylate kinase AK1 gene knockout heart under metabolic stress. J Biol Chem 275: 41424-41429, 2000
48. Dzeja PP, Bortolon R, Perez-Terzic C, Holmuhamedov EL, Terzic A: Energetic communication between mitochondria and nucleus directed by catalyzed phosphotransfer. Proc Natl Acad Sci USA 99: 10156-10161, 2002
49. ATP channels limits energy depletion in the guinea pig heart. Am J Physiol 269: H734-H742, 1995
50. Zingman LV, Hodgson DM, Bast PH, Kane GC, Perez-Terzic C, Gumina RJ, Pucar D, Bienengraeber M, Dzeja PP, Miki T, Seino S, Alekseev AE, Terzic A: Kir6.2 is required for adaptation to stress. Proc Natl Acad Sci USA 99: 13278-13283, 2002
51. Pucar D, Bast P, Gumina RJ, Lim L, Drahl C, Juranic N, Macura S, Janssen E, Wieringa B, Terzic A, Dzeja PP. Adenylate kinase AK1 knockout heart: Energetics and functional performance under ischemia-reperfusion. Am J Physiol 283: H776-H782, 2002
52. Ghosh MC, Jencks WP: Phosphorylation of the sodium-potassium adenosinetriphosphatase with adenosine triphosphate and sodium ion that requires subconformations in addition to principal E1 and E2 conformations of the enzyme. Biochemistry 35: 12587-12590, 1996
53. 31P NMR detection of subcellular creatine kinase fluxes in the perfused rat heart: Contractility modifies energy transfer pathways. J Biol Chem 277: 18469-18476, 2002
54. ATP channels. Cell Physiol Biochem 9: 227-241, 1999
55. Kusuoka H, Inoue M, Tsuneoka Y, Watari H, Hori M, Abe H: Augmented energy consumption during early systole as a mechanism of cyclical changes in high-energy phosphates in myocardium assessed by phosphorus nuclear magnetic resonance. Jpn Circ J 49: 1099-107, 1985