P-glycoprotein inhibition by glibenclamide and related compounds

Pflugers Archiv European Journal of Physiology

Volumn 437, Issue 5, 1999, Pages 652-660

  Golstein, P E ^a   Boom, A ^a   Van Geffel, J ^a   Jacobs, P ^a   Masereel, B ^b   Beauwens, R ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b NONE

Author keywords

ABC transporters; Anti cancer drugs; Multidrug resistance; Sulphonylurea

Indexed keywords

ABC TRANSPORTER; AZIDOPINE; BM 208; BM 223; COLCHICINE; CYCLOSPORIN; DRUG RECEPTOR; GLIBENCLAMIDE; GLYCOPROTEIN P; GUANIDINE DERIVATIVE; MULTIDRUG RESISTANCE PROTEIN; N1 [4 [BETA (2 METHOXY 5 CHLOROBENZOYLAMINO)ETHYL]BENZENESULPHONYL] N2 [4 METHYLCYCLOHEXYL]CYANOGUANIDINE; N1 [4 [BETA (2 METHOXY 5 CHLOROBENZOYLAMINO)ETHYL]BENZENESULPHONYL] N2 CYCLOHEXYLCYANOGUANIDINE; PACLITAXEL; SULFONYLUREA DERIVATIVE; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG; VERAPAMIL; VINBLASTINE;

ANIMAL CELL; ARTICLE; CYTOTOXICITY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; INHIBITION KINETICS; MULTIDRUG RESISTANCE; NONHUMAN; OPOSSUM; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RAT;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CELL ADHESION; CELL LINE; CELL MEMBRANE; CELL SURVIVAL; COLCHICINE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; GLYBURIDE; HUMANS; HYPOGLYCEMIC AGENTS; IMMUNOCHEMISTRY; OPOSSUMS; P-GLYCOPROTEIN; PHOTOAFFINITY LABELS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN BINDING; RATS; RECEPTORS, DRUG; SULFONYLUREA COMPOUNDS;

EID: 0032904076     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240050829     Document Type: Article

References (41)

1. Aguilar-Bryan L, Nichols CG, Wechsler SW, Clement JP IV, Boyd AE III, Gonzalez G, Herrera-Sosa H, Nguy K, Bryan J, Nelson DA (1995) Cloning of the β cell high affinity sulfonylurea receptor: a regulator of insulin secretion. Science 268: 423-425
2. r 190,000 multidrug resistance protein (MRP) in dug-selected and transfected tumor cells. Cancer Res 55:102-110
3. Beck WT, Mueller TJ, Tanzer LR (1979) Altered membrane glycoproteins in Vinca alkaloid-resistant human leukemic lymphoblasts. Cancer Res 39:2070-2076
4. Bradley G, Juranka PF, Ling V (1988) Mechanism of multidrug resistance. Biochim Biophys Acta 948:87-128
5. Bruggemann EP, Germann UA, Gottesman MM, Pastan I (1989) Two different regions of phosphoglycoprotein are photoaffinity-labeled by azidopine. J Biol Chem 264:15483-15488
6. Choi K, Chen CJ, Kriegler M, Roninson IB (1988) An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene. Cell 53:519-529
7. Chou TC, Depew KM, Zheng YH, Safer ML, Chan D, Helfrich B, Zatorska D, Zatorski A, Bornmann W, Danishefsky SJ (1998) Reversal of anticancer multidrug resistance by the ardeemins. Proc Natl Acad Sci USA 95:8369-8374
8. De Greef C, Heyden S van der, Viana F, Eggermont J, De Bruijn EA, Raeymakers L, Droogmans G, Nilius B (1995) Lack of correlation between mdr-1 expression and volume-activation of chloride-currents in rat colon cancer cells. Pflügers Arch 430:296-298
9. Dong M, Penin F, Baggetto LG (1996) Efficient purification and reconstitution of P-glycoprotein for functional and structural studies. J Biol Chem 271:28875-28883
10. Foxwell BMJ, Mackie A, Ling V, Ryffel B (1989) Identification of the multidrug resistance-related P-glycoprotein as a cyclosporine binding protein. Mol Pharmacol 36:543-546
11. Gala JL, McLachlan JM, Bell DR, Michaux JL, Ma DD (1994) Specificity of inimunocytochemistry for detecting P-glycoprotein in haematological malignancies. J Clin Pathol 47:619-624
12. rev. Jpn J Cancer Res 84:1201-1208
13. Gottesman MM, Pastan I (1993) Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 62:385-427
14. 1-adrenergic receptor and the calcium channel bind to a common domain in P-glycoprotein. J Biol Chem 265:4394-4401
15. Gros P, Dhir R, Croop J, Talbot F (1991) A single amino acid substitution strongly modulates the activity and substrate specificity of the mouse Mdr1 and Mdr3 drug efflux pump. Proc Natl Acad Sci USA 88:7289-7293
16. Gupta KP, Ward NE, Gravitt KR, Bergman PJ, O'Brian CA (1996) Partial reversal of multidrug resistance in human breast cancer cells by an N-myristoylated protein kinase C-α pseudo-substrate peptide. J Biol Chem 271:2102-2111
17. Harker GW, Bauer D, Etiz BB, Newman RA, Sikic BI (1986) Verapamil-mediated sensitization of doxorubicin-selected pleiotropic resistance in human sarcoma cells: selectivity for drugs which produce DNA scission. Cancer Res 46:2369-2373
18. Higgins CF (1992) ABC transporters: from microorganisms to man. Annu Rev Cell Biol 8:67-113
19. m of the pump. Biochim Biophys Acta 1027:116-122
20. Huang Yang CP, Mellado W, Horwitz SB (1988) Azidopine photoaffinity labeling of multidrug resistance-associated glycoproteins. Biochem Pharmacol 37:1417-1421
21. KATP: an inward rectifier subunit plus the sulfonylurea receptor. Science 270:1166-1170
22. + channels. Neuron 16:1011-1017
23. Jaffrézou JP, Herbert JM, Levade T, Gau MN, Chatelain P, Laurent G (1991) Reversal of multidrug resistance by calcium channel blocker SR33557 without photoaffinity labeling of P-glycoprotein. J Biol Chem 266:19858-19864
24. - and taurine efflux from HeLa cells by P-glycoprotein blockers correlates with calmodulin inhibition. J Biol Chem 269:29389-29394
25. Leveille-Webster CR, Arias IM (1995) The biology of the P-glycoproteins. J Membr Biol 143:89-102
26. Lieberman DM, Reithmeier RAF, Ling V, Charuk JHM, Goldberg H, Skorecki KL (1989) Identification of P-glycoprotein in renal brush border membranes. Biochem Biophys Res Commun 162:244-252
27. Masereel B, Lebrun P, Dogné JM, de Tullio P, Pirotte B, Pochet L, Diouf O, Delarge J (1996) First synthesis of 4-substituted benzenesulfonylcyanoguanidines. Tetrahedron Lett 37: 7253-7254
28. Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63
29. Peterson GL (1977) A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal Biochem 83:346-356
30. Riordan JR (1993) The cystic fibrosis transmembrane conductance regulator. Annu Rev Physiol 55:609-630
31. Safa AR (1988) Photoaffinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil. Proc Natl Acad Sci USA 85:7187-7191
32. Safa AR, Glover CJ, Sewell JL, Meyers MB, Biedler L, Felsted RL (1987) Identification of the multidrug resistance-related membrane glycoprotein as an acceptor for calcium channel blockers. J Biol Chem 262:7884-7888
33. Scheffer GL, Wijngaard PLJ, Flens MJ, Izquierdo MA, Slovak ML, Pinedo HM, Meijer CJL, Clevers HC, Sheper RJ (1995) The drug resistance-related protein LRP is the human major vault protein. Nat Med 1:578-582
34. Schultz BD, DeRoos ADG, Venglarik CJ, Singh AK, Frizzell RA, Bridges RJ (1996) Glibenclamide blockade of CFTR chloride channels. Am J Physiol 271:L192-L200
35. + channel regulators on cystic fibrosis transmembrane conductance regulator chloride currents. J Gen Physiol 100:573-591
36. Smith CD, Zilfou JT (1995) Circumvention of P-glycoprotein-mediated multiple drug resistance by phosphorylation modulators is independent of protein kinases. J Biol Chem 270: 28145-28152
37. Thiebaut F, Tsuruo T, Hamada H, Gottesman MM, Pastan I, Willingham MC (1987) Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci USA 84:7735-7738
38. Van de Vrie W, Gheuens EEO, Bijma A, De Bruijn EA, Marquet RL, Van Oosterom AT, Eggermont AMM (1991) A syngeneic in vivo model of a multidrug resistant colon carcinoma, CC531 in the WAG rat. Proc Am Assoc Cancer Res 32:365-365
39. Verovski VN, Van den Berge DL, Delvaeye MM, Scheper RJ, De Neve WJ, Storme GA (1996) Low-level doxorubicin resistance in P-glycoprotein-negative human pancreatic tumour PSN1/ADR cells implicates a brefeldin A-sensitive mechanism of drug extrusion. Br J Cancer 73:596-602
40. Wiechelman K, Braun R, Fitzpatrick J (1988) Investigation of the bicinchoninic acid protein assay: identification of the groups responsible for color formation. Anal Biochem 175: 231-237
41. Yamazaki H, Schneider E, Myers C, Sinha BK (1994) Oncogene overexpression and de novo drug-resistance in human prostate cancer cells. Biochim Biophys Acta 1226:89-96