메뉴 건너뛰기




Volumn 34, Issue 1, 2003, Pages 93-102

A low molecular weight antioxidant decreases weight and lowers tumor incidence

Author keywords

Aging; Antioxidant; Carcinogenesis; Free radicals; Nitroxide; Obesity; Oxidative stress; Uncoupling protein

Indexed keywords

ANTIOXIDANT; DRINKING WATER; FREE RADICAL; HEAT SHOCK PROTEIN 70; LEPTIN; NITROXIDE; TEMPOL; UNCOUPLING PROTEIN 2;

EID: 0037222224     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(02)01193-0     Document Type: Article
Times cited : (92)

References (57)
  • 1
    • 0021964203 scopus 로고
    • Prooxidant states and tumor promotion
    • Cerutti P.A. Prooxidant states and tumor promotion. Science. 227:1985;375-381.
    • (1985) Science , vol.227 , pp. 375-381
    • Cerutti, P.A.1
  • 2
    • 0027171266 scopus 로고
    • Oxidants, antioxidants, and the degenerative diseases of aging
    • Ames B.N., Shigenaga M.K., Hagen T.M. Oxidants, antioxidants, and the degenerative diseases of aging. Proc. Natl. Acad. Sci. USA. 90:1993;7915-7922.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7915-7922
    • Ames, B.N.1    Shigenaga, M.K.2    Hagen, T.M.3
  • 3
    • 0001590580 scopus 로고    scopus 로고
    • Free radicals, other reactive species, and disease
    • B. Halliwell, & J.M.C. Gutteridge. Oxford, UK: Oxford University Press
    • Halliwell B., Gutteridge J.M.C. Free radicals, other reactive species, and disease. Halliwell B., Gutteridge J.M.C. Free radicals in biology and medicine. 1999;617-783 Oxford University Press, Oxford, UK.
    • (1999) Free radicals in biology and medicine , pp. 617-783
    • Halliwell, B.1    Gutteridge, J.M.C.2
  • 4
    • 0034213186 scopus 로고    scopus 로고
    • The evolution of free radicals and oxidative stress
    • McCord J.M. The evolution of free radicals and oxidative stress. Am. J. Med. 108:2000;652-659.
    • (2000) Am. J. Med , vol.108 , pp. 652-659
    • McCord, J.M.1
  • 5
    • 0018776894 scopus 로고
    • Hydroperoxide metabolism in mammalian organs
    • Chance B., Sies H., Boveris A. Hydroperoxide metabolism in mammalian organs. Physiol. Rev. 59:1979;527-605.
    • (1979) Physiol. Rev , vol.59 , pp. 527-605
    • Chance, B.1    Sies, H.2    Boveris, A.3
  • 6
    • 84911635706 scopus 로고
    • W. Bors, M. Saran, & D. Tait. Berlin: Walter deGruyter
    • Sies H. Detoxification of oxygen free radicals. Bors W., Saran M., Tait D. 1984;653-661 Walter deGruyter, Berlin.
    • (1984) Detoxification of Oxygen Free Radicals , pp. 653-661
    • Sies, H.1
  • 7
    • 0025309791 scopus 로고
    • Mitochondrial mutations may increase oxidative stress: Implications for carcinogenesis and aging?
    • Bandy B., Davison A.J. Mitochondrial mutations may increase oxidative stress implications for carcinogenesis and aging? Free Radic. Biol. Med. 8:1990;523-539.
    • (1990) Free Radic. Biol. Med , vol.8 , pp. 523-539
    • Bandy, B.1    Davison, A.J.2
  • 8
    • 0025976425 scopus 로고
    • Oxidant stress and carcinogenesis
    • Cerutti P.A. Oxidant stress and carcinogenesis. Eur. J. Clin. Invest. 21:1991;1-5.
    • (1991) Eur. J. Clin. Invest , vol.21 , pp. 1-5
    • Cerutti, P.A.1
  • 9
    • 0030038103 scopus 로고    scopus 로고
    • Oxidative stress, caloric restriction, and aging
    • Sohal R.S., Weindruch R. Oxidative stress, caloric restriction, and aging. Science. 273:1996;59-63.
    • (1996) Science , vol.273 , pp. 59-63
    • Sohal, R.S.1    Weindruch, R.2
  • 13
    • 0024224555 scopus 로고
    • A novel metal-free low molecular weight superoxide dismutase mimic
    • Samuni A., Krishna C.M., Riesz P., Finkelstein E., Russo A. A novel metal-free low molecular weight superoxide dismutase mimic. J. Biol. Chem. 263:1988;17921-17924.
    • (1988) J. Biol. Chem , vol.263 , pp. 17921-17924
    • Samuni, A.1    Krishna, C.M.2    Riesz, P.3    Finkelstein, E.4    Russo, A.5
  • 18
    • 77049308856 scopus 로고
    • Aging: A theory based on free radical and radiation biology
    • Harman D. Aging a theory based on free radical and radiation biology. J. Gerontol. 11:1956;298-300.
    • (1956) J. Gerontol , vol.11 , pp. 298-300
    • Harman, D.1
  • 19
    • 0029587352 scopus 로고
    • Role of antioxidant nutrients in aging: Overview
    • Harman D. Role of antioxidant nutrients in aging overview. Age. 18:1995;51-62.
    • (1995) Age , vol.18 , pp. 51-62
    • Harman, D.1
  • 22
    • 0018199057 scopus 로고
    • Preparation and characterization of mitchondria and submitchondrial particles of rat liver and liver-derived tissues
    • D.M. Prescott. New York: Academic Press
    • Pedersen P.L., Greenawalt J.W., Reynafarje B., Hullihen J., Decker G.L., Soper J.W., Bustamente E. Preparation and characterization of mitchondria and submitchondrial particles of rat liver and liver-derived tissues. Prescott D.M. Methods in cell biology. 1978;411-481 Academic Press, New York.
    • (1978) Methods in cell biology , pp. 411-481
    • Pedersen, P.L.1    Greenawalt, J.W.2    Reynafarje, B.3    Hullihen, J.4    Decker, G.L.5    Soper, J.W.6    Bustamente, E.7
  • 25
    • 0027442518 scopus 로고
    • Two computer programs using logit transformation for the analysis of S-shaped curves
    • Rieger E., Bijl J.J., Rieger M. Two computer programs using logit transformation for the analysis of S-shaped curves. Comput. Biol. Med. 23:1993;389-397.
    • (1993) Comput. Biol. Med , vol.23 , pp. 389-397
    • Rieger, E.1    Bijl, J.J.2    Rieger, M.3
  • 26
    • 0001047561 scopus 로고
    • The effect of retardation of growth on the breeding period and duration of life span in rats
    • Osborn T.B., Mendel C.B., Ferry E.L. The effect of retardation of growth on the breeding period and duration of life span in rats. Science. 45:1917;294-295.
    • (1917) Science , vol.45 , pp. 294-295
    • Osborn, T.B.1    Mendel, C.B.2    Ferry, E.L.3
  • 27
    • 0002458132 scopus 로고
    • The effect of retarded growth upon the length of life span and upon the ultimate body size
    • McCay C.M., Crowell M.F., Maynard L.A. The effect of retarded growth upon the length of life span and upon the ultimate body size. J. Nutr. 10:1935;63-79.
    • (1935) J. Nutr , vol.10 , pp. 63-79
    • McCay, C.M.1    Crowell, M.F.2    Maynard, L.A.3
  • 28
    • 0029684517 scopus 로고    scopus 로고
    • Caloric restriction and aging
    • Weindruch R. Caloric restriction and aging. Sci. Am. 274:1996;46-52.
    • (1996) Sci. Am , vol.274 , pp. 46-52
    • Weindruch, R.1
  • 29
    • 0012289133 scopus 로고    scopus 로고
    • Environmental enrichment: Does it reduce barbering in mice?
    • DeLuca A.M. Environmental enrichment does it reduce barbering in mice? AWIC Newslett. 8:1997;7-8.
    • (1997) AWIC Newslett , vol.8 , pp. 7-8
    • DeLuca, A.M.1
  • 30
    • 0034650763 scopus 로고    scopus 로고
    • The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP, and AtUCP
    • Ricquier D., Bouillaud F. The uncoupling protein homologues UCP1, UCP2, UCP3, StUCP, and AtUCP. Biochem. J. 345:2000;161-179.
    • (2000) Biochem. J , vol.345 , pp. 161-179
    • Ricquier, D.1    Bouillaud, F.2
  • 32
    • 0028220114 scopus 로고
    • Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster.
    • Orr W.C., Sohal R.S. Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science. 263:1994;1128-1130.
    • (1994) Science , vol.263 , pp. 1128-1130
    • Orr, W.C.1    Sohal, R.S.2
  • 33
    • 0034669375 scopus 로고    scopus 로고
    • Restriction of energy intake, energy expenditure, and aging
    • Ramsey J.J., Harper M.E., Weindruch R. Restriction of energy intake, energy expenditure, and aging. Free Radic. Biol. Med. 29:2000;946-968.
    • (2000) Free Radic. Biol. Med , vol.29 , pp. 946-968
    • Ramsey, J.J.1    Harper, M.E.2    Weindruch, R.3
  • 34
    • 0024655426 scopus 로고
    • Food, reproduction and longevity: Is the extended lifespan of calorie-restricted animals an evolutionary adaptation?
    • Holliday R. Food, reproduction and longevity is the extended lifespan of calorie-restricted animals an evolutionary adaptation? Bioessays. 10:1989;125-127.
    • (1989) Bioessays , vol.10 , pp. 125-127
    • Holliday, R.1
  • 35
    • 0032879458 scopus 로고    scopus 로고
    • Controlling caloric consumption: Protocols for rodents and rhesus monkeys
    • Pugh T.D., Klopp R.G., Weindruch R. Controlling caloric consumption protocols for rodents and rhesus monkeys. Neurobiol. Aging. 20:1999;157-165.
    • (1999) Neurobiol. Aging , vol.20 , pp. 157-165
    • Pugh, T.D.1    Klopp, R.G.2    Weindruch, R.3
  • 36
    • 0022828058 scopus 로고
    • Influence of caloric intake on experimental carcinogenesis: A review
    • Kritchevsky D., Klurfeld D.M. Influence of caloric intake on experimental carcinogenesis a review. Adv. Exp. Med. Biol. 206:1986;55-68.
    • (1986) Adv. Exp. Med. Biol , vol.206 , pp. 55-68
    • Kritchevsky, D.1    Klurfeld, D.M.2
  • 38
    • 0023227110 scopus 로고
    • Total calories, body weight, and tumor incidence in mice
    • Albanes D. Total calories, body weight, and tumor incidence in mice. Cancer Res. 47:1987;1987-1992.
    • (1987) Cancer Res , vol.47 , pp. 1987-1992
    • Albanes, D.1
  • 39
    • 0026505347 scopus 로고
    • Antimutagenicity of a low molecular weight superoxide dismutase mimic against oxidative mutagens
    • DeGraff W.G., Krishna C.M., Russo A., Mitchell J.B. Antimutagenicity of a low molecular weight superoxide dismutase mimic against oxidative mutagens. Environ. Mol. Mutagen. 19:1992;21-26.
    • (1992) Environ. Mol. Mutagen , vol.19 , pp. 21-26
    • DeGraff, W.G.1    Krishna, C.M.2    Russo, A.3    Mitchell, J.B.4
  • 40
    • 0030784838 scopus 로고    scopus 로고
    • Weight regulation, leptin, and growth hormone
    • Considine R.V. Weight regulation, leptin, and growth hormone. Hormone Res. 48:1997;116-121.
    • (1997) Hormone Res , vol.48 , pp. 116-121
    • Considine, R.V.1
  • 41
    • 0024583546 scopus 로고
    • Effects of oxygen on the metabolism of nitroxide spin labels in cells
    • Chen K., Glockner J.F., Morse P.D., Swartz H.M. Effects of oxygen on the metabolism of nitroxide spin labels in cells. Biochemistry. 28:1989;2496-2501.
    • (1989) Biochemistry , vol.28 , pp. 2496-2501
    • Chen, K.1    Glockner, J.F.2    Morse, P.D.3    Swartz, H.M.4
  • 42
    • 0031793127 scopus 로고    scopus 로고
    • Heat shock protein 70 kDa: Molecular biology, biochemistry, and physiology
    • Kiang J.G., Tsokos G.C. Heat shock protein 70 kDa molecular biology, biochemistry, and physiology. Pharmacol. Ther. 80:1998;183-201.
    • (1998) Pharmacol. Ther , vol.80 , pp. 183-201
    • Kiang, J.G.1    Tsokos, G.C.2
  • 43
    • 0031925150 scopus 로고    scopus 로고
    • Hsp70 chaperone systems: Diversity of cellular functions and mechanism of action
    • Mayer M.P., Bukau B. Hsp70 chaperone systems diversity of cellular functions and mechanism of action. Biol. Chem. 379:1998;261-268.
    • (1998) Biol. Chem , vol.379 , pp. 261-268
    • Mayer, M.P.1    Bukau, B.2
  • 44
    • 0034097491 scopus 로고    scopus 로고
    • Stress proteins of 70 kDa in chronically exercised skeletal muscle
    • Gonzalez B., Hernando R., Manso R. Stress proteins of 70 kDa in chronically exercised skeletal muscle. Pflgers Arch. 440:2000;42-49.
    • (2000) Pflgers Arch , vol.440 , pp. 42-49
    • Gonzalez, B.1    Hernando, R.2    Manso, R.3
  • 45
    • 0034332648 scopus 로고    scopus 로고
    • Endurance training increases stimulation of uncoupling of skeletal muscle mitochrondria in humans by non-esterified fatty acids: An uncoupling-protein-mediated effect?
    • Tonkonogi M., Krook A., Walsh B., Sahlin K. Endurance training increases stimulation of uncoupling of skeletal muscle mitochrondria in humans by non-esterified fatty acids an uncoupling-protein-mediated effect? Biochem. J. 351:2000;805-810.
    • (2000) Biochem. J , vol.351 , pp. 805-810
    • Tonkonogi, M.1    Krook, A.2    Walsh, B.3    Sahlin, K.4
  • 46
    • 20644466225 scopus 로고    scopus 로고
    • Tumor necrosis factor increases mitochondrial oxidant production and induces expression of uncoupling protein-2 in the regenerating mice [correction of rat] liver
    • Lee F.Y., Li Y., Zhu H., Yang S., Lin H.Z., Trush M., Diehl A.M. Tumor necrosis factor increases mitochondrial oxidant production and induces expression of uncoupling protein-2 in the regenerating mice [correction of rat] liver. Hepatology. 29:1999;677-687.
    • (1999) Hepatology , vol.29 , pp. 677-687
    • Lee, F.Y.1    Li, Y.2    Zhu, H.3    Yang, S.4    Lin, H.Z.5    Trush, M.6    Diehl, A.M.7
  • 48
    • 0033823015 scopus 로고    scopus 로고
    • Decreased fatty acid synthesis due to mitochondrial uncoupling in adipose tissue
    • Rossmeisl M., Syrovy I., Baumruk F., Flachs P., Janovska P., Kopecky J. Decreased fatty acid synthesis due to mitochondrial uncoupling in adipose tissue. FASEB J. 14:2000;1793-1800.
    • (2000) FASEB J , vol.14 , pp. 1793-1800
    • Rossmeisl, M.1    Syrovy, I.2    Baumruk, F.3    Flachs, P.4    Janovska, P.5    Kopecky, J.6
  • 49
    • 0034194239 scopus 로고    scopus 로고
    • Increased gene expression of brown fat uncoupling protein (UCP)1 and skeletal muscle UCP2 and UCP3 in MAC16-induced cancer cachexia
    • Bing C., Brown M., King P., Collins P., Tisdale M.J., Williams G. Increased gene expression of brown fat uncoupling protein (UCP)1 and skeletal muscle UCP2 and UCP3 in MAC16-induced cancer cachexia. Cancer Res. 60:2000;2405-2410.
    • (2000) Cancer Res , vol.60 , pp. 2405-2410
    • Bing, C.1    Brown, M.2    King, P.3    Collins, P.4    Tisdale, M.J.5    Williams, G.6
  • 51
    • 0028803718 scopus 로고
    • The gerontogenes age-1 and daf-2 determine metabolic rate potential in aging Caenorhabditis elegans
    • Vanfleteren J.R., De Vreese A. The gerontogenes age-1 and daf-2 determine metabolic rate potential in aging Caenorhabditis elegans. FASEB J. 9:1995;1355-1361.
    • (1995) FASEB J , vol.9 , pp. 1355-1361
    • Vanfleteren, J.R.1    De Vreese, A.2
  • 54
    • 0034011261 scopus 로고    scopus 로고
    • Oxyradicals and DNA damage
    • Marnett L.J. Oxyradicals and DNA damage. Carcinogenesis. 21:2000;361-370.
    • (2000) Carcinogenesis , vol.21 , pp. 361-370
    • Marnett, L.J.1
  • 55
    • 0032053876 scopus 로고    scopus 로고
    • Antiproliferative effect of the piperidine nitroxide Tempol on neoplastic and nonneoplastic mammalian cell lines
    • Gariboldi M.B., Lucchi S., Caserini C., Supino R., Oliva C., Monti E. Antiproliferative effect of the piperidine nitroxide Tempol on neoplastic and nonneoplastic mammalian cell lines. Free Radic. Biol. Med. 24:1998;913-923.
    • (1998) Free Radic. Biol. Med , vol.24 , pp. 913-923
    • Gariboldi, M.B.1    Lucchi, S.2    Caserini, C.3    Supino, R.4    Oliva, C.5    Monti, E.6
  • 56
    • 0033797023 scopus 로고    scopus 로고
    • The nitroxide Tempol induces oxidative stress, p21WAF1/CIP1, and cell death in HL60 cells
    • Gariboldi M.B., Rimoldi V., Supino R., Favini E., Monti E. The nitroxide Tempol induces oxidative stress, p21WAF1/CIP1, and cell death in HL60 cells. Free Radic. Biol. Med. 29:2000;633-641.
    • (2000) Free Radic. Biol. Med , vol.29 , pp. 633-641
    • Gariboldi, M.B.1    Rimoldi, V.2    Supino, R.3    Favini, E.4    Monti, E.5
  • 57
    • 0032572831 scopus 로고    scopus 로고
    • Studies of structure-activity relationship of nitroxide free radicals and their precursors as modifiers against oxidative damage
    • Krishna M.C., DeGraff W., Hankovszky O.H., Sar C.P., Kalai T., Jeko J., Russo A., Mitchell J.B., Hideg K. Studies of structure-activity relationship of nitroxide free radicals and their precursors as modifiers against oxidative damage. J. Med. Chem. 41:1998;3477-3492.
    • (1998) J. Med. Chem , vol.41 , pp. 3477-3492
    • Krishna, M.C.1    DeGraff, W.2    Hankovszky, O.H.3    Sar, C.P.4    Kalai, T.5    Jeko, J.6    Russo, A.7    Mitchell, J.B.8    Hideg, K.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.