Activation of polyamine catabolism profoundly alters tissue polyamine pools and affects hair growth and female fertility in transgenic mice overexpressing spermidine/spermine N1-acetyltransferase

Journal of Biological Chemistry

Volumn 272, Issue 30, 1997, Pages 18746-18751

  Pietilä, Marko ^a   Alhonen, Leena ^b   Halmekyto, Maria ^a   Kanter, Peter ^b   Jänne, Juhani ^b,c   Porter, Carl W ^b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b ROSWELL PARK CANCER INSTITUTE   (United States)

^c UICC ^*

Author keywords

[No Author keywords available]

Indexed keywords

N1 ACETYLSPERMIDINE; PUTRESCINE; SPERMIDINE; SPERMINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; FEMALE; FEMALE FERTILITY; HAIR GROWTH; MALE; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PHENOTYPE; POLYAMINE SYNTHESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ACETYLTRANSFERASES; ANIMALS; BLOTTING, NORTHERN; CELL DIFFERENTIATION; EPIDERMIS; FEMALE; GENE DOSAGE; GENE EXPRESSION; HAIR; INFERTILITY, FEMALE; MICE; MICE, INBRED BALB C; MICE, INBRED DBA; MICE, TRANSGENIC; PHENOTYPE; POLYAMINES; PUTRESCINE; RNA, MESSENGER; SPERMIDINE; SPERMINE; TISSUE DISTRIBUTION;

ANIMALIA; MUS MUSCULUS;

EID: 0030755394     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.30.18746     Document Type: Article

References (39)

1. Porter, C. W., Regenass, U., and Bergeron R. J. (1992) in Falk Symposium on Polyamines in the Gastrointestinal Tract (Dowling, R. H., Fölsch, U. R., and Löser, C., eds) pp. 301-322, Kluwer Academic Publishers Group, Drodrecht, Netherlands
2. Jänne, J., Alhonen, L., and Leinonen, P. (1991) Ann. Med. 23, 241-259
3. Marton, L. J., and Pegg, A. E. (1995) Annu. Rev. Pharmacol. Toxicol. 35, 55-91
4. Sistonen, L., Keski-Oja, J., Ulmanen, I., Hölttä, E., Wikgren, B.-J., and Alitalo, K. (1987) Exp. Cell Res. 168, 518-530
5. Polvinen, K., Sinervirta, R., Aihonen, L., and Janne, J. (1988) Biochem. Biophys. Res. Commun. 155, 373-378
6. Auvinen, M., Paasinen, A., Andersson, L. C., and Hölttä, E. (1992) Nature 360, 355-358
7. Moshier, J. A., Dosescu, J., Skunca, M., and Luk, G. D. (1993) Cancer Res. 53, 2618-2622
8. Hibshoosh, H., Johnson, M., and Weinstein, I. B. (1991) Oncogene 6, 739-743
9. Bello-Fernandez, C., Packham, G., and Cleveland, J. L. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 7804-7808
10. Wagner, A. J., Meyers, C., Laimins, L. A., and Hay, N. (1993) Cell Growth & Differ. 4, 879-883
11. Peña, A., Reddy, C. D., Wu, S., Hickok, N. J., Reddy, E. P., Yumet, G., Soprano, D. R., and Soprano, K. J. (1993) J. Biol. Chem. 268, 27277-27285
12. Lutz, W., Stöhr, M., Schürmann, J., Wenzel, A., Lohr, A., and Schwab, M. (1696) Oncogene 13, 803-812
13. Hakovirta, H., Keiski, A., Toppari, J., Halmekytö, M., Alhonen, L., Jänne, J., and Parvinen, M. (1993) Mol. Endocrinol. 7, 1430-1436
14. Halmekytö, M., Hyttinen, J.-M., Sinervirta, R., Utriainen, M., Myöhänen, S., Voipio, H.-M., Wahlfors, J., Syrjänen, S., Syrjänen, K., Alhonen, L., and Jänne, J. (1991) J. Biol. Chem. 266, 19746-19751
15. Alhonen, L., Halmekytö, M., Kosma, V.-M., Wahlfors, J., Kauppinen, R., and Jänne, J. (1995) Int. J. Cancer 63, 402-404
16. Pilz, R. B., Steglich, C., and Scheffler, I. E. (1990) J. Biol. Chem. 265, 8880-8886
17. Casero, R. A., and Pegg, A. E. (1993) FASEB J. 7, 653-661
18. Parry, L., Lopez-Ballester, J., Wiest, L., and Pegg, A. E. (1995) Biochemistry 34, 2701-2709
19. Parry, L., Balaña Fouce, R., and Pegg, A. E. (1995) Biochem. J. 305, 451-458
20. Vargiu, C., and Persson, L. (1994) FEBS Lett. 355, 163-165
21. Casero, R. A., Jr., Celano, P., Ervin, S. J., Porter, C. W., Bergeron, R. J., and Libby, P. R. (1989) Cancer Res. 49, 3829-3833
22. Shappell, N. W., Miller, J. T., Bergeron, R. J., and Porter, C. W. (1992) Anticancer Res. 12, 1083-1089
23. Hogan, B., Constantini, F., and Lacy, E. (1986) Manipulating the Mouse Embryo, pp. 1-322, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
24. Fogel-Petrovic, M., Kramer, D. L., Ganis, B., Casero, R. A., Jr., and Porter, C. W. (1993) Biochim. Biophys. Acta 1216, 255-264
25. Blin, N., and Stafford, D. W. (1976) Nucleic Acids Res. 3, 2303-2306
26. Chomczynski, P., and Sacchi, N. (1987) Anal. Biochem. 162, 156-159
27. Ross, J. R. (1976) J. Mol. Biol. 106, 403-420
28. Fogel-Petrovic, M., Vujcic, S., Brown, P. J., Haddox, M. K., and Porter, C. W. (1996) Biochemistry 35, 14436-14444
29. Cachon-Gonzales, M. B., Fenner, S., Coffin, J. M., Moran, C., Best, S., and Stoye, J. P. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 7717-7721
30. Bernacki, R. J., Oberman, E. J., Seweryniak, K. E., Atwood, A., Bergeron, R. J., and Porter, C. W. (1995) Clin. Cancer Res. 1, 847-857
31. Kramer, D., Mett, H., Evans, A., Regenass, U., Diegelman, P., and Porter, C. W. (1995) J. Biol. Chem. 270, 2124-2132
32. Fogel-Petrovic, M., Shappell, N. W., Bergeron, R. J., and Porter, C. W. (1993) J. Biol. Chem. 268, 19118-19125
33. Fogel-Petrovic, M., Vujcic, S., Miller, J., and Porter, C. W. (1996) FEBS Lett. 391, 89-94
34. Halmekytö, M., Alakuijala, L., Alhonen, L., and Jänne, J. (1993) Biochem. J. 291, 505-508
35. Stoye, J. P., Fenner, S., Greenoak, G. E., Moran, C., and Coffin, J. M. (1988) Cell 54, 383-391
36. Jones, J. M., Elder, J. T., Simin, K., Keller, S. A., and Meisler, M. H. (1993) Mamm. Genome 4, 639-643
37. Megosh, L., Gilmour, S. K., Rosson, D., Peralta Soler, A., Blessing, M., Sawicki, J. A., and O'Brien, T. G. (1995) Cancer Res. 55, 4205-4209
38. Peralta-Soler, A., Gilliard, G., Megosh, L. C., and O'Brien, T. G. (1996) J. Invest. Dermatol. 106, 1108-1113
39. Furth, P. A., St Onge, L., Boger, H., Gruss, P., Gossen, M., Kistner, A., Bujard, H., and Hennighausen, L. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 9302-9306