Chemistry and biology of ramoplanin: A lipoglycodepsipeptide with potent antibiotic activity

Chemical Reviews

Volumn 105, Issue 2, 2005, Pages 449-475

  Walker, Suzanne ^a   Chen, Lan ^a   Hu, Yanan ^b   Rew, Yosup ^c   Shin, Dongwoo ^c   Boger, Dale L ^c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN-ANTIBODY REACTIONS; BACTERIA; BINDING ENERGY; BIOCHEMISTRY; BIOSYNTHESIS; DEGRADATION; ENZYMES; MEDICAL APPLICATIONS; MOLECULAR STRUCTURE; POLYPEPTIDES; REACTION KINETICS;

LIPOGLYCODEPSIPEPTIDE; MOLECULAR RECOGNITION; POTENT ANTIBIOTIC ACTIVITY; RAMOPLANIN; STRUCTURE-ACTIVITY STUDIES;

ANTIBIOTICS;

ANTIINFECTIVE AGENT; DEPSIPEPTIDE; N ACETYLGLUCOSAMINYLTRANSFERASE; OUTER MEMBRANE PROTEIN; RAMOPLANIN; UDP N ACETYLGLUCOSAMINE N ACETYLMURAMYL (PENTAPEPTIDE)PYROPHOSPHORYL UNDECAPRENOL N ACETYLGLUCOSAMINE TRANSFERASE; UDP-N-ACETYLGLUCOSAMINE-N-ACETYLMURAMYL-(PENTAPEPTIDE)PYROPHOSPHORYL-UNDECAPRENOL N-ACETYLGLUCOSAMINE TRANSFERASE;

CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GRAM POSITIVE BACTERIUM; MICROBIOLOGICAL EXAMINATION; REVIEW; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTI-BACTERIAL AGENTS; BACTERIAL OUTER MEMBRANE PROTEINS; DEPSIPEPTIDES; GRAM-POSITIVE BACTERIA; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; N-ACETYLGLUCOSAMINYLTRANSFERASES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 14844340653     PISSN: 00092665     EISSN: None     Source Type: Journal    
DOI: 10.1021/cr030106n     Document Type: Review

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