-
2
-
-
0027835533
-
Does increased mortality favor the evolution of increased senscence?
-
Abrams PA. 1993. Does increased mortality favor the evolution of increased senscence? Evolution 47:877-87
-
(1993)
Evolution
, vol.47
, pp. 877-887
-
-
Abrams, P.A.1
-
3
-
-
0033576579
-
Regulation of lifespan by sensory perception in Caenorhabditis elegans
-
Apfeld J, Kenyon C. 1999. Regulation of lifespan by sensory perception in Caenorhabditis elegans. Nature 402:804-9
-
(1999)
Nature
, vol.402
, pp. 804-809
-
-
Apfeld, J.1
Kenyon, C.2
-
4
-
-
0026058667
-
Elevated paraquat resistance can be used as a bioassay for longevity in a genetically based long-lived strain of Drosophila
-
Arking R, Buck S, Berrios A, Dwyer S, Baker GT III. 1991. Elevated paraquat resistance can be used as a bioassay for longevity in a genetically based long-lived strain of Drosophila. Dev. Genet. 12:362-70
-
(1991)
Dev. Genet.
, vol.12
, pp. 362-370
-
-
Arking, R.1
Buck, S.2
Berrios, A.3
Dwyer, S.4
Baker III, G.T.5
-
5
-
-
17344385104
-
Identical longevity phenotypes are characterized by different patterns of gene expression and oxidative damage
-
Arking R, Burde V, Graves K, Hari R, Feldman E, et al. 2000. Identical longevity phenotypes are characterized by different patterns of gene expression and oxidative damage. Exp. Gerontol. 35:353-73
-
(2000)
Exp. Gerontol.
, vol.35
, pp. 353-373
-
-
Arking, R.1
Burde, V.2
Graves, K.3
Hari, R.4
Feldman, E.5
-
6
-
-
0034032863
-
Forward and reverse selection for longevity in Drosophila is characterized by alteration of antioxidant gene expression and oxidative damage patterns
-
Arking R, Burde V, Graves K, Hari R, Feldman E, et al. 2000. Forward and reverse selection for longevity in Drosophila is characterized by alteration of antioxidant gene expression and oxidative damage patterns. Exp. Gerontol. 35:167-85
-
(2000)
Exp. Gerontol.
, vol.35
, pp. 167-185
-
-
Arking, R.1
Burde, V.2
Graves, K.3
Hari, R.4
Feldman, E.5
-
7
-
-
0030297512
-
Factors contributing to the plasticity of the extendedlongevity phenotypes of Drosophila
-
Arking R, Force AG, Dudas SP, Buck S, Baker GT. 1996. Factors contributing to the plasticity of the extendedlongevity phenotypes of Drosophila. Exp. Gerontol. 31:623-43
-
(1996)
Exp. Gerontol.
, vol.31
, pp. 623-643
-
-
Arking, R.1
Force, A.G.2
Dudas, S.P.3
Buck, S.4
Baker, G.T.5
-
8
-
-
0026012740
-
Mammalian aging, metabolism, and ecology: Evidence from the bats and marsupials
-
Austad SN, Fischer KE. 1991. Mammalian aging, metabolism, and ecology: evidence from the bats and marsupials. J. Gerontol. 46:B47-53
-
(1991)
J. Gerontol.
, vol.46
-
-
Austad, S.N.1
Fischer, K.E.2
-
9
-
-
0033369476
-
Mitochondrial oxygen radical generation and leak: Sites of production in state 4 and 3, organ specificity, and relation to aging and longevity
-
Barja G. 1999. Mitochondrial oxygen radical generation and leak: sites of production in state 4 and 3, organ specificity, and relation to aging and longevity. J. Bioenerg. Biomembr. 31:347-66
-
(1999)
J. Bioenerg. Biomembr.
, vol.31
, pp. 347-366
-
-
Barja, G.1
-
10
-
-
0033972463
-
Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals
-
Barja G, Herrero A. 2000. Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals. FASEB J. 14:312-18
-
(2000)
FASEB J.
, vol.14
, pp. 312-318
-
-
Barja, G.1
Herrero, A.2
-
11
-
-
0027280338
-
Pathological implications of nitric oxide, superoxide and peroxynitrite formation
-
Beckman JS, Crow JP. 1993. Pathological implications of nitric oxide, superoxide and peroxynitrite formation. Biochem. Soc. Trans. 21:330-34
-
(1993)
Biochem. Soc. Trans.
, vol.21
, pp. 330-334
-
-
Beckman, J.S.1
Crow, J.P.2
-
12
-
-
0021288856
-
Determination of the production of superoxide radicals and hydrogen peroxide in mitochondria
-
Boveris A. 1984. Determination of the production of superoxide radicals and hydrogen peroxide in mitochondria. Methods Enzymol. 105:429-39
-
(1984)
Methods Enzymol.
, vol.105
, pp. 429-439
-
-
Boveris, A.1
-
13
-
-
0002437327
-
Production of superoxide radicals and hydrogen peroxide in mitochondria
-
ed. LW Oberley, Boca Raton, FL: CRC Press
-
Boveris A, Cadenas E. 1982. Production of superoxide radicals and hydrogen peroxide in mitochondria. In Superoxide Dismutase, ed. LW Oberley, pp. 16-30. Boca Raton, FL: CRC Press
-
(1982)
Superoxide Dismutase
, pp. 16-30
-
-
Boveris, A.1
Cadenas, E.2
-
14
-
-
0027244097
-
Mitochondrial DNA remains intact during Drosophila aging, but the levels of mitochondrial transcripts are significantly reduced
-
Calleja M, Pena P, Ugalde C, Ferreiro C, Marco R, Garesse R. 1993. Mitochondrial DNA remains intact during Drosophila aging, but the levels of mitochondrial transcripts are significantly reduced. J. Biol. Chem. 268:18891-97
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 18891-18897
-
-
Calleja, M.1
Pena, P.2
Ugalde, C.3
Ferreiro, C.4
Marco, R.5
Garesse, R.6
-
15
-
-
0035053574
-
Insect biodemography
-
13a. Carey JR. 2001. Insect biodemography. Annu. Rev. Entomol. 46:79-110
-
(2001)
Annu. Rev. Entomol.
, vol.46
, pp. 79-110
-
-
Carey, J.R.1
-
16
-
-
0030463128
-
Female fitness in Drosophila melanogaster: An interaction between the effect of nutrition and of encounter rate with males
-
Chapman T, Partridge L. 1996. Female fitness in Drosophila melanogaster: an interaction between the effect of nutrition and of encounter rate with males. Proc. R. Soc. London Ser. B 263:755-59
-
(1996)
Proc. R. Soc. London Ser. B
, vol.263
, pp. 755-759
-
-
Chapman, T.1
Partridge, L.2
-
18
-
-
0035820667
-
Patterns of age-specific means and genetic variances of mortality rates predicted by the mutation-accumulation theory of ageing
-
Charlesworth B. 2001. Patterns of age-specific means and genetic variances of mortality rates predicted by the mutation-accumulation theory of ageing. J. Theor. Biol. 210:47-65
-
(2001)
J. Theor. Biol.
, vol.210
, pp. 47-65
-
-
Charlesworth, B.1
-
19
-
-
0029994356
-
Age-specific inbreeding depression and components of genetic variance in relation to the evolution of senescence
-
Charlesworth B, Hughes KA. 1996. Age-specific inbreeding depression and components of genetic variance in relation to the evolution of senescence. Proc. Natl. Acad. Sci. USA 93:6140-45
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 6140-6145
-
-
Charlesworth, B.1
Hughes, K.A.2
-
20
-
-
0000823129
-
The maintenance of genetic variation in life history traits
-
ed. RS Singh, CB Krimbas, Cambridge, UK: Cambridge Univ. Press
-
Charlesworth B, Hughes KA. 2000. The maintenance of genetic variation in life history traits. In Evolutionary Genetics from Molecules to Morphology, ed. RS Singh, CB Krimbas, pp. 369-91. Cambridge, UK: Cambridge Univ. Press
-
(2000)
Evolutionary Genetics from Molecules to Morphology
, pp. 369-391
-
-
Charlesworth, B.1
Hughes, K.A.2
-
21
-
-
0025650442
-
Prolongation of the yeast life span by the v-Ha-RAS oncogene
-
Chen JB, Sun J, Jazwinski SM. 1990. Prolongation of the yeast life span by the v-Ha-RAS oncogene. Mol. Microbiol. 4:2081-86
-
(1990)
Mol. Microbiol.
, vol.4
, pp. 2081-2086
-
-
Chen, J.B.1
Sun, J.2
Jazwinski, S.M.3
-
22
-
-
0027880487
-
Phenotypic plasticity and selection in Drosophila life-history evolution. I. Nutrition and the cost of reproduction
-
Chippindale AK. 1993. Phenotypic plasticity and selection in Drosophila life-history evolution. I. Nutrition and the cost of reproduction. J. Evol. Biol. 6:171-93
-
(1993)
J. Evol. Biol.
, vol.6
, pp. 171-193
-
-
Chippindale, A.K.1
-
23
-
-
0037066518
-
Dietary restriction in long-lived dwarf flies
-
Clancy DJ, Gems D, Hafen E, Leevers SJ, Partridge L. 2002. Dietary restriction in long-lived dwarf flies. Science 296:319
-
(2002)
Science
, vol.296
, pp. 319
-
-
Clancy, D.J.1
Gems, D.2
Hafen, E.3
Leevers, S.J.4
Partridge, L.5
-
24
-
-
0035815414
-
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
-
Clancy DJ, Gems D, Harshman LG, Oldham S, Stocker H, et al. 2001. Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science 292:104-6
-
(2001)
Science
, vol.292
, pp. 104-106
-
-
Clancy, D.J.1
Gems, D.2
Harshman, L.G.3
Oldham, S.4
Stocker, H.5
-
25
-
-
77049158727
-
The population consequences of life-history phenomena
-
Cole LC. 1954. The population consequences of life-history phenomena. Q. Rev. Biol. 29:103-37
-
(1954)
Q. Rev. Biol.
, vol.29
, pp. 103-137
-
-
Cole, L.C.1
-
26
-
-
0043095549
-
Dopa decarboxylase (Ddc) affects variation in Drosophila longevity
-
De Luca M, Roshina NV, Geiger-Thornsberry GL, Lyman RF, Pasyukova EG, Mackay TFC. 2003. Dopa decarboxylase (Ddc) affects variation in Drosophila longevity. Nat. Genet. 34:429-33
-
(2003)
Nat. Genet.
, vol.34
, pp. 429-433
-
-
De Luca, M.1
Roshina, N.V.2
Geiger-Thornsberry, G.L.3
Lyman, R.F.4
Pasyukova, E.G.5
Mackay, T.F.C.6
-
27
-
-
0028807085
-
The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans
-
Dorman JB, Albinder B, Shroyer T, Kenyon C. 1995. The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans. Genetics 141:1399-406
-
(1995)
Genetics
, vol.141
, pp. 1399-1406
-
-
Dorman, J.B.1
Albinder, B.2
Shroyer, T.3
Kenyon, C.4
-
28
-
-
18344405929
-
Generation of superoxide anion by mitochondria and impairment of their functions during anoxia and reoxygenation in vitro
-
Du G, Mouithys-Mickalad A, Sluse FE. 1998. Generation of superoxide anion by mitochondria and impairment of their functions during anoxia and reoxygenation in vitro. Free Radic. Biol. Med. 25:1066-74
-
(1998)
Free Radic. Biol. Med.
, vol.25
, pp. 1066-1074
-
-
Du, G.1
Mouithys-Mickalad, A.2
Sluse, F.E.3
-
29
-
-
0029087068
-
A coordinate upregulation of antioxidant gene activities is associated with the delayed onset of senescence in a longlived strain of Drosophila
-
Dudas SP, Arking R. 1995. A coordinate upregulation of antioxidant gene activities is associated with the delayed onset of senescence in a longlived strain of Drosophila. J. Gerontol. A 50:B117-27
-
(1995)
J. Gerontol. A
, vol.50
-
-
Dudas, S.P.1
Arking, R.2
-
30
-
-
0035089611
-
The senescence of Daphnia from risky and safe habitats
-
Dudycha JL. 2001. The senescence of Daphnia from risky and safe habitats. Ecol. Lett. 4:102-5
-
(2001)
Ecol. Lett.
, vol.4
, pp. 102-105
-
-
Dudycha, J.L.1
-
31
-
-
0000652657
-
Recherces generales sur la mortalite et la multiplication
-
Euler L. 1760. Recherces generales sur la mortalite et la multiplication. Mem. Acad. R. Sci. Bell. Lett. 16:144-64
-
(1760)
Mem. Acad. R. Sci. Bell. Lett.
, vol.16
, pp. 144-164
-
-
Euler, L.1
-
32
-
-
0042422247
-
The chronological life span of Saccharomyces cerevisiae
-
Fabrizio P, Longo VD. 2003. The chronological life span of Saccharomyces cerevisiae. Aging Cell 2:73-81
-
(2003)
Aging Cell
, vol.2
, pp. 73-81
-
-
Fabrizio, P.1
Longo, V.D.2
-
33
-
-
0035853552
-
Regulation of longevity and stress resistance by Sch9 in yeast
-
Fabrizio P, Pozza F, Pletcher SD, Gendron CM, Longo VD. 2001. Regulation of longevity and stress resistance by Sch9 in yeast. Science 292:288-90
-
(2001)
Science
, vol.292
, pp. 288-290
-
-
Fabrizio, P.1
Pozza, F.2
Pletcher, S.D.3
Gendron, C.M.4
Longo, V.D.5
-
34
-
-
0037458617
-
Structural and functional characteristics of two sodium-coupled dicarboxylate transporters (ceNaDC1 and ceNaDC2) from Caenorhabditis elegans and their relevance to life span
-
Fei YJ, Inoue K, Ganapathy V. 2003. Structural and functional characteristics of two sodium-coupled dicarboxylate transporters (ceNaDC1 and ceNaDC2) from Caenorhabditis elegans and their relevance to life span. J. Biol. Chem. 278:6136-44
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 6136-6144
-
-
Fei, Y.J.1
Inoue, K.2
Ganapathy, V.3
-
35
-
-
0033118981
-
CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans
-
Felkai S, Ewbank JJ, Lemieux J, Labbe JC, Brown GG, Hekimi S. 1999. CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans. EMBO Eur. Mol. Biol. Organ. J. 18:1783-92
-
(1999)
EMBO Eur. Mol. Biol. Organ. J.
, vol.18
, pp. 1783-1792
-
-
Felkai, S.1
Ewbank, J.J.2
Lemieux, J.3
Labbe, J.C.4
Brown, G.G.5
Hekimi, S.6
-
37
-
-
0035060368
-
Oxidative biochemical markers; clues to understanding aging in long-lived species
-
Floyd RAWM, Hensley K. 2001 Oxidative biochemical markers; clues to understanding aging in long-lived species. Exp. Gerontol. 36:619-40
-
(2001)
Exp. Gerontol.
, vol.36
, pp. 619-640
-
-
Floyd, R.A.W.M.1
Hensley, K.2
-
38
-
-
0029610090
-
Comparative biochemical and stress analysis of genetically selected Drosophila strains with different longevities
-
Force AG, Staples T, Soliman S, Arking R. 1995. Comparative biochemical and stress analysis of genetically selected Drosophila strains with different longevities. Dev. Genet. 17:340-51
-
(1995)
Dev. Genet.
, vol.17
, pp. 340-351
-
-
Force, A.G.1
Staples, T.2
Soliman, S.3
Arking, R.4
-
39
-
-
0001837912
-
Superoxide radical and hydrogen peroxide in mitochondria
-
ed. WA Pryor, New York: Academic
-
Foreman HJ, Boveris A. 1982. Superoxide radical and hydrogen peroxide in mitochondria. In Free Radicals in Biology, ed. WA Pryor, pp. 65-90. New York: Academic
-
(1982)
Free Radicals in Biology
, pp. 65-90
-
-
Foreman, H.J.1
Boveris, A.2
-
40
-
-
0029053451
-
Superoxide radical and superoxide dismutase
-
Fridovitch I. 1995. Superoxide radical and superoxide dismutase. Annu. Rev. Biochem. 64:97-112
-
(1995)
Annu. Rev. Biochem.
, vol.64
, pp. 97-112
-
-
Fridovitch, I.1
-
41
-
-
0033606902
-
Nematode ageing: Putting metabolic theories to the test
-
38a. Gems D. 1999. Nematode ageing: putting metabolic theories to the test. Curr. Biol. 9:R614-16
-
(1999)
Curr. Biol.
, vol.9
-
-
Gems, D.1
-
42
-
-
5444227933
-
Ageing
-
ed. DL Lee, London: Taylor & Francis. 635 pp.
-
Gems D. 2002. Ageing. In The Biology of Nematodes, ed. DL Lee, pp. 413-56. London: Taylor & Francis. 635 pp.
-
(2002)
The Biology of Nematodes
, pp. 413-456
-
-
Gems, D.1
-
43
-
-
0031685525
-
Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans
-
Gems D, Sutton AJ, Sundermeyer ML, Albert PS, King KV, et al. 1998. Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans. Genetics 150:129-55
-
(1998)
Genetics
, vol.150
, pp. 129-155
-
-
Gems, D.1
Sutton, A.J.2
Sundermeyer, M.L.3
Albert, P.S.4
King, K.V.5
-
44
-
-
0035169919
-
Age-specific mortality and reproduction respond to adult dietary restriction in Drosophila melanogaster
-
Good TP, Tatar M. 2001. Age-specific mortality and reproduction respond to adult dietary restriction in Drosophila melanogaster. J. Insect Physiol. 47:1467-73
-
(2001)
J. Insect Physiol.
, vol.47
, pp. 1467-1473
-
-
Good, T.P.1
Tatar, M.2
-
45
-
-
0034193776
-
Sir2 links chromatic silencing, metabolism, and aging
-
Guarente L. 2000. Sir2 links chromatic silencing, metabolism, and aging. Genes Dev. 14:1021-26
-
(2000)
Genes Dev.
, vol.14
, pp. 1021-1026
-
-
Guarente, L.1
-
46
-
-
0034626747
-
Genetic pathways that regulate ageing in model organisms
-
Guarente L, Kenyon C. 2000. Genetic pathways that regulate ageing in model organisms. Nature 408:255-62
-
(2000)
Nature
, vol.408
, pp. 255-262
-
-
Guarente, L.1
Kenyon, C.2
-
47
-
-
0013942563
-
The moulding of senescence by natural selection
-
43a. Hamilton WD. 1966. The moulding of senescence by natural selection. J. Theor. Biol. 12:12-45
-
(1966)
J. Theor. Biol.
, vol.12
, pp. 12-45
-
-
Hamilton, W.D.1
-
48
-
-
0038154017
-
A homologue of elongation factor 1γ regulates methionine sulfoxide reductase A gene expression in Saccharomyces cerevisiae
-
Hanbauer I, Boja ES, Moskovitz J. 2003. A homologue of elongation factor 1γ regulates methionine sulfoxide reductase A gene expression in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 100:8199-204
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8199-8204
-
-
Hanbauer, I.1
Boja, E.S.2
Moskovitz, J.3
-
49
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
Harman D. 1956. Aging: a theory based on free radical and radiation chemistry. J. Gerontol. 11:298-300
-
(1956)
J. Gerontol.
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
50
-
-
0000456613
-
Role of free radicals in mutation, cancer, aging and the maintenance of life
-
Harman D. 1962. Role of free radicals in mutation, cancer, aging and the maintenance of life. Radiat. Res. 16:753-63
-
(1962)
Radiat. Res.
, vol.16
, pp. 753-763
-
-
Harman, D.1
-
51
-
-
0033045832
-
Selection for starvation resistance in Drosophila melanogaster: Physiological correlates, enzyme activities and multiple stress responses
-
Harshman LG, Hoffmann AA, Clark AG. 1999. Selection for starvation resistance in Drosophila melanogaster: physiological correlates, enzyme activities and multiple stress responses. J. Evol. Biol. 12:370-79
-
(1999)
J. Evol. Biol.
, vol.12
, pp. 370-379
-
-
Harshman, L.G.1
Hoffmann, A.A.2
Clark, A.G.3
-
52
-
-
0037470539
-
Genetics and the specificity of the aging process
-
Hekimi S, Guarente L. 2003. Genetics and the specificity of the aging process. Science 299:1351-54
-
(2003)
Science
, vol.299
, pp. 1351-1354
-
-
Hekimi, S.1
Guarente, L.2
-
53
-
-
0346155806
-
Genetics of aging in the fruit fly, Drosophila melanogaster
-
Helfand SL, Rogina B. 2003. Genetics of aging in the fruit fly, Drosophila melanogaster. Annu. Rev. Genet. 37:329-48
-
(2003)
Annu. Rev. Genet.
, vol.37
, pp. 329-348
-
-
Helfand, S.L.1
Rogina, B.2
-
55
-
-
0029520541
-
The evolution of avian senescence patterns: Implications for understanding primary aging processes
-
Holmes DJ, Austad SN. 1995. The evolution of avian senescence patterns: implications for understanding primary aging processes. Am. Zool. 35:307-17
-
(1995)
Am. Zool.
, vol.35
, pp. 307-317
-
-
Holmes, D.J.1
Austad, S.N.2
-
57
-
-
0032782364
-
The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans
-
Honda Y, Honda S. 1999. The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans. FASEB J. 13:1385-93
-
(1999)
FASEB J.
, vol.13
, pp. 1385-1393
-
-
Honda, Y.1
Honda, S.2
-
58
-
-
12744261594
-
-
Deleted in proof
-
Deleted in proof
-
-
-
-
59
-
-
0033609291
-
Signals from the reproductive system regulate the lifespan of C. elegans
-
Hsin H, Kenyon C. 1999. Signals from the reproductive system regulate the lifespan of C. elegans. Nature 399:362-66
-
(1999)
Nature
, vol.399
, pp. 362-366
-
-
Hsin, H.1
Kenyon, C.2
-
60
-
-
0038701745
-
Regulation of aging and age-related disease by DAF-16 and heat-shock factor
-
Hsu AL, Murphy CT, Kenyon C. 2003. Regulation of aging and age-related disease by DAF-16 and heat-shock factor. Science 300:1142-45
-
(2003)
Science
, vol.300
, pp. 1142-1145
-
-
Hsu, A.L.1
Murphy, C.T.2
Kenyon, C.3
-
61
-
-
0028843224
-
The evolutionary genetics of male life-history characters in Drosophila melanogaster
-
Hughes KA. 1995. The evolutionary genetics of male life-history characters in Drosophila melanogaster. Evolution 49:521-37
-
(1995)
Evolution
, vol.49
, pp. 521-537
-
-
Hughes, K.A.1
-
62
-
-
0028940943
-
The inbreeding decline and average dominance of genes affecting male life-history characters in Drosophila melanogaster
-
Hughes KA. 1995. The inbreeding decline and average dominance of genes affecting male life-history characters in Drosophila melanogaster. Genet. Res. 65:41-52
-
(1995)
Genet. Res.
, vol.65
, pp. 41-52
-
-
Hughes, K.A.1
-
64
-
-
0025004091
-
Increased life-span of age-1 mutants in Caenorhabditis elegans and lower Gompertz rate of aging
-
Johnson TE. 1990. Increased life-span of age-1 mutants in Caenorhabditis elegans and lower Gompertz rate of aging. Science 249:908-12
-
(1990)
Science
, vol.249
, pp. 908-912
-
-
Johnson, T.E.1
-
65
-
-
0030688040
-
Extraordinary lifespans in ants: A test of evolutionary theories of ageing
-
Keller L, Genoud M. 1997. Extraordinary lifespans in ants: a test of evolutionary theories of ageing. Nature 389:958-60
-
(1997)
Nature
, vol.389
, pp. 958-960
-
-
Keller, L.1
Genoud, M.2
-
66
-
-
0035917440
-
A conserved regulatory system for aging
-
Kenyon C. 2001. A conserved regulatory system for aging. Cell 105:165-68
-
(2001)
Cell
, vol.105
, pp. 165-168
-
-
Kenyon, C.1
-
67
-
-
0027771804
-
A C. elegans mutant that lives twice as long as wild type
-
Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R. 1993. A C. elegans mutant that lives twice as long as wild type. Nature 366:461-64
-
(1993)
Nature
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
-
68
-
-
0031021432
-
Heat-induced longevity extension in Drosophila. 1. Heat treatment, mortality, and thermotolerance
-
Khazaeli AA, Tatar M, Pletcher SD, Curtsinger JW. 1997. Heat-induced longevity extension in Drosophila. 1. Heat treatment, mortality, and thermotolerance. J. Gerontol. A 52:B48-52
-
(1997)
J. Gerontol. A
, vol.52
-
-
Khazaeli, A.A.1
Tatar, M.2
Pletcher, S.D.3
Curtsinger, J.W.4
-
69
-
-
0032831936
-
Modulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae
-
Kim S, Benguria A, Lai CY, Jazwinski SM. 1999. Modulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae. Mol. Biol. Cell 10:3125-36
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 3125-3136
-
-
Kim, S.1
Benguria, A.2
Lai, C.Y.3
Jazwinski, S.M.4
-
70
-
-
0030813398
-
Daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
-
Kimura KD, Tissenbaum HA, Liu Y Ruvkun G. 1997. Daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277:942-46
-
(1997)
Science
, vol.277
, pp. 942-946
-
-
Kimura, K.D.1
Tissenbaum, H.A.2
Liu, Y.3
Ruvkun, G.4
-
71
-
-
0033104457
-
Aging-specific expression of Drosophila hsp22
-
King V, Tower J. 1999. Aging-specific expression of Drosophila hsp22. Dev. Biol. 207:107-18
-
(1999)
Dev. Biol.
, vol.207
, pp. 107-118
-
-
King, V.1
Tower, J.2
-
73
-
-
0001904727
-
The disposable soma theory of aging
-
ed. DE Harrison, Caldwell, NJ: Telford Press
-
Kirkwood TBL. 1990. The disposable soma theory of aging. In Genetic Effects on Aging II, ed. DE Harrison, pp. 9-19. Caldwell, NJ: Telford Press
-
(1990)
Genetic Effects on Aging II
, pp. 9-19
-
-
Kirkwood, T.B.L.1
-
75
-
-
0037195166
-
Functional characterization and immunolocalization of the transporter encoded by the life-extending gene Indy
-
Knauf F, Rogina B, Jiang ZR, Aronson PS, Helfand SL. 2002. Functional characterization and immunolocalization of the transporter encoded by the life-extending gene Indy. Proc. Natl. Acad. Sci. USA 99:14315-19
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 14315-14319
-
-
Knauf, F.1
Rogina, B.2
Jiang, Z.R.3
Aronson, P.S.4
Helfand, S.L.5
-
76
-
-
0020664368
-
Genetic variability in mating activity of Drosophila melanogaster males
-
Kosuda K. 1983. Genetic variability in mating activity of Drosophila melanogaster males. Experientia 39:100-1
-
(1983)
Experientia
, vol.39
, pp. 100-101
-
-
Kosuda, K.1
-
77
-
-
0022058311
-
The aging effect on male mating activity in Drosophila melanogaster
-
Kosuda K. 1985. The aging effect on male mating activity in Drosophila melanogaster. Behav. Genet. 15:297-303
-
(1985)
Behav. Genet.
, vol.15
, pp. 297-303
-
-
Kosuda, K.1
-
78
-
-
0027517591
-
Comparison of mitochondrial prooxidant generation and antioxidant defenses between rat and pigeon: Possible basis of variation in longevity and metabolic potential
-
Ku HH, Sohal RS. 1993. Comparison of mitochondrial prooxidant generation and antioxidant defenses between rat and pigeon: possible basis of variation in longevity and metabolic potential. Mech. Ageing Dev. 72:67-76
-
(1993)
Mech. Ageing Dev.
, vol.72
, pp. 67-76
-
-
Ku, H.H.1
Sohal, R.S.2
-
79
-
-
0033511746
-
Drosophila selected for extended longevity are more sensitive to heat shock
-
Kuether K, Arking R. 1999. Drosophila selected for extended longevity are more sensitive to heat shock. Age Media 22:175-80
-
(1999)
Age Media
, vol.22
, pp. 175-180
-
-
Kuether, K.1
Arking, R.2
-
80
-
-
0029776793
-
Determination of life-span in Caenorhabditis elegans by four clock genes
-
Lakowski B, Hekimi S. 1996. Determination of life-span in Caenorhabditis elegans by four clock genes. Science 272:1010-13
-
(1996)
Science
, vol.272
, pp. 1010-1013
-
-
Lakowski, B.1
Hekimi, S.2
-
81
-
-
0037016442
-
Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q
-
Larsen PL, Clarke CF. 2002. Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q. Science 295:120-23
-
(2002)
Science
, vol.295
, pp. 120-123
-
-
Larsen, P.L.1
Clarke, C.F.2
-
82
-
-
0042631525
-
Rethinking the evolutionary theory of aging: Transfers, not births, shape senescence in social species
-
Lee RD. 2003. Rethinking the evolutionary theory of aging: Transfers, not births, shape senescence in social species. Proc. Natl. Acad. Sci. USA 100:9637-42
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 9637-9642
-
-
Lee, R.D.1
-
83
-
-
0030657540
-
daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans
-
Lin K, Dorman JB, Rodan A, Kenyon C. 1997. daf-16: an HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 278:1319-22
-
(1997)
Science
, vol.278
, pp. 1319-1322
-
-
Lin, K.1
Dorman, J.B.2
Rodan, A.3
Kenyon, C.4
-
84
-
-
0034703217
-
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
-
Lin SJ, Defossez PA, Guarente L. 2000. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 289:2126-28
-
(2000)
Science
, vol.289
, pp. 2126-2128
-
-
Lin, S.J.1
Defossez, P.A.2
Guarente, L.3
-
85
-
-
0032582489
-
Extended life-span and stress resistance in the Drosophila mutant methuselah
-
Lin YJ, Seroude L, Benzer S. 1998. Extended life-span and stress resistance in the Drosophila mutant methuselah. Science 282:943-46
-
(1998)
Science
, vol.282
, pp. 943-946
-
-
Lin, Y.J.1
Seroude, L.2
Benzer, S.3
-
86
-
-
0029123058
-
Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress
-
Lithgow GJ, White TM, Melov S, Johnson TE. 1995. Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress. Proc. Natl. Acad. Sci. USA 92:7540-44
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7540-7544
-
-
Lithgow, G.J.1
White, T.M.2
Melov, S.3
Johnson, T.E.4
-
87
-
-
0033405860
-
Mutations in signal transduction proteins increase stress resistance and longevity in yeast, nematodes, fruit flies, and mammalian neuronal cells
-
Longo VD. 1999. Mutations in signal transduction proteins increase stress resistance and longevity in yeast, nematodes, fruit flies, and mammalian neuronal cells. Neurobiol. Aging 20:479-86
-
(1999)
Neurobiol. Aging
, vol.20
, pp. 479-486
-
-
Longo, V.D.1
-
88
-
-
0037470488
-
Evolutionary medicine: From dwarf model systems to healthy centenarians?
-
Longo VD, Finch CE. 2003. Evolutionary medicine: from dwarf model systems to healthy centenarians? Science 299:1342-46
-
(2003)
Science
, vol.299
, pp. 1342-1346
-
-
Longo, V.D.1
Finch, C.E.2
-
89
-
-
0031944770
-
Selection for longevity confers resistance to low-temperature stress in Drosophila melanogaster
-
Luckinbill LS. 1998. Selection for longevity confers resistance to low-temperature stress in Drosophila melanogaster. J. Gerontol. A 53:B147-53
-
(1998)
J. Gerontol. A
, vol.53
-
-
Luckinbill, L.S.1
-
90
-
-
0000977248
-
Selection for delayed senescence in Drosophila melanogaster
-
Luckinbill LS, Arking R, Clare MJ, Cirocco WC, Buck SA. 1984. Selection for delayed senescence in Drosophila melanogaster. Evolution 38:996-1003
-
(1984)
Evolution
, vol.38
, pp. 996-1003
-
-
Luckinbill, L.S.1
Arking, R.2
Clare, M.J.3
Cirocco, W.C.4
Buck, S.A.5
-
91
-
-
84966175214
-
Selection for life span in Drosophila melanogaster
-
Luckinbill LS, Clare MJ. 1985. Selection for life span in Drosophila melanogaster. Heredity 55:9-18
-
(1985)
Heredity
, vol.55
, pp. 9-18
-
-
Luckinbill, L.S.1
Clare, M.J.2
-
92
-
-
0141766912
-
Demography of dietary restriction and death in Drosophila
-
Mair W, Goymer P, Pletcher SD, Partridge L. 2003. Demography of dietary restriction and death in Drosophila. Science 301:1731-33
-
(2003)
Science
, vol.301
, pp. 1731-1733
-
-
Mair, W.1
Goymer, P.2
Pletcher, S.D.3
Partridge, L.4
-
93
-
-
0037452882
-
Conditional tradeoffs between aging and organismal performance of Indy long-lived mutant flies
-
Marden JH, Rogina B, Montooth KL, Helfand SL. 2003. Conditional tradeoffs between aging and organismal performance of Indy long-lived mutant flies. Proc. Natl. Acad. Sci. USA 100:3369-73
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 3369-3373
-
-
Marden, J.H.1
Rogina, B.2
Montooth, K.L.3
Helfand, S.L.4
-
94
-
-
12744260222
-
-
Deleted in proof
-
Deleted in proof
-
-
-
-
95
-
-
0000552314
-
The effects of temperature and of egg-laying on the longevity of Drosophila subobscura
-
Maynard Smith J. 1958. The effects of temperature and of egg-laying on the longevity of Drosophila subobscura. J. Exp. Biol. 35:832-42
-
(1958)
J. Exp. Biol.
, vol.35
, pp. 832-842
-
-
Maynard Smith, J.1
-
96
-
-
0000853087
-
Prolongation of the life of Drosophila subobscura by brief exposure of adults to a high temperature
-
Maynard Smith J. 1958. Prolongation of the life of Drosophila subobscura by brief exposure of adults to a high temperature. Nature 181:496-97
-
(1958)
Nature
, vol.181
, pp. 496-497
-
-
Maynard Smith, J.1
-
97
-
-
0025117953
-
An attempt at a rational classification of theories of ageing
-
Medvedev ZA. 1990. An attempt at a rational classification of theories of ageing. Biol. Rev. 65:375-98
-
(1990)
Biol. Rev.
, vol.65
, pp. 375-398
-
-
Medvedev, Z.A.1
-
98
-
-
0034284973
-
Extension of life-span with superoxide dismutase/catalase mimetics
-
Melov S, Ravenscroft J, Malik S, Gill MS, Walker DW, Clayton PE, et al. 2000. Extension of life-span with superoxide dismutase/catalase mimetics. Science 289:1567-69
-
(2000)
Science
, vol.289
, pp. 1567-1569
-
-
Melov, S.1
Ravenscroft, J.2
Malik, S.3
Gill, M.S.4
Walker, D.W.5
Clayton, P.E.6
-
99
-
-
0035896557
-
Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans
-
Miyadera H, Amino H, Hiraishi A, Taka H, Murayama K, et al. 2001. Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans. J. Biol. Chem. 276:7713-16
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 7713-7716
-
-
Miyadera, H.1
Amino, H.2
Hiraishi, A.3
Taka, H.4
Murayama, K.5
-
100
-
-
0035097846
-
Antioxidant status and stress resistance in long- And short-lived lines of Drosophila melanogaster
-
Mockett RJ, Orr WC, Rahmandar JJ, Sohal BH, Sohal RS. 2001. Antioxidant status and stress resistance in long- and short-lived lines of Drosophila melanogaster. Exp. Gerontol. 36:441-63
-
(2001)
Exp. Gerontol.
, vol.36
, pp. 441-463
-
-
Mockett, R.J.1
Orr, W.C.2
Rahmandar, J.J.3
Sohal, B.H.4
Sohal, R.S.5
-
101
-
-
12744255274
-
-
Deleted in proof
-
Deleted in proof
-
-
-
-
102
-
-
0029621249
-
Changes in the respiratory chain complexes activities and in the mitochondrial DNA content during ageing in D. subobscura
-
Morel F, Mazet F, Touraille S, Alziari S. 1995. Changes in the respiratory chain complexes activities and in the mitochondrial DNA content during ageing in D. subobscura. Mech. Ageing Dev. 84:171-81
-
(1995)
Mech. Ageing Dev.
, vol.84
, pp. 171-181
-
-
Morel, F.1
Mazet, F.2
Touraille, S.3
Alziari, S.4
-
103
-
-
0742323000
-
Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones
-
Morley JF, Morimoto RI. 2004. Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones. Mol. Biol. Cell 15:657-64
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 657-664
-
-
Morley, J.F.1
Morimoto, R.I.2
-
104
-
-
0029768753
-
A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
-
Morris JZ, Tissenbaum HA, Ruvkun G. 1996. A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans. Nature 382:536-39
-
(1996)
Nature
, vol.382
, pp. 536-539
-
-
Morris, J.Z.1
Tissenbaum, H.A.2
Ruvkun, G.3
-
105
-
-
0035818520
-
Methionine sulfoxide reductase (MsrA) is a regulator of antioxidant defense and lifespan in mammals
-
Moskovitz J, Bar-Noy S, Williams WM, Requena J, Berlett BS, Stadtman ER. 2001. Methionine sulfoxide reductase (MsrA) is a regulator of antioxidant defense and lifespan in mammals. Proc. Natl. Acad. Sci. USA 98:12920-25
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12920-12925
-
-
Moskovitz, J.1
Bar-Noy, S.2
Williams, W.M.3
Requena, J.4
Berlett, B.S.5
Stadtman, E.R.6
-
106
-
-
12744274884
-
-
Deleted in proof
-
Deleted in proof
-
-
-
-
107
-
-
0033748782
-
Postponed aging and desiccation resistance in Drosophila melanogaster
-
Nghiem D, Gibbs AG, Rose MR, Bradley TJ. 2000. Postponed aging and desiccation resistance in Drosophila melanogaster. Exp. Gerontol. 35:957-69
-
(2000)
Exp. Gerontol.
, vol.35
, pp. 957-969
-
-
Nghiem, D.1
Gibbs, A.G.2
Rose, M.R.3
Bradley, T.J.4
-
108
-
-
0038712734
-
Effects of overexpression of copper-zinc and manganese superoxide dismutases, catalase, and thioredoxin reductase genes on longevity in Drosophila melanogaster
-
Orr WC, Mockett RJ, Benes JJ, Sohal RS. 2003. Effects of overexpression of copper-zinc and manganese superoxide dismutases, catalase, and thioredoxin reductase genes on longevity in Drosophila melanogaster. J. Biol. Chem. 278:26418-22
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 26418-26422
-
-
Orr, W.C.1
Mockett, R.J.2
Benes, J.J.3
Sohal, R.S.4
-
109
-
-
0028220114
-
Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster
-
Orr WC, Sohal RS. 1994. Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science 263:1128-30
-
(1994)
Science
, vol.263
, pp. 1128-1130
-
-
Orr, W.C.1
Sohal, R.S.2
-
110
-
-
1542408999
-
Decreased expression of Cu-Zn superoxide dismutase 1 in ants with extreme lifespan
-
Parker JD, Parker KM, Sohal BH, Sohal RS, Keller L. 2004. Decreased expression of Cu-Zn superoxide dismutase 1 in ants with extreme lifespan. Proc. Natl. Acad. Sci. USA 101:3486-89
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3486-3489
-
-
Parker, J.D.1
Parker, K.M.2
Sohal, B.H.3
Sohal, R.S.4
Keller, L.5
-
111
-
-
0031864164
-
Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons
-
Parkes TL, Elia AJ, Dickinson D, Hilliker AJ, Phillips JP, Boulianne GL. 1998. Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons. Nat. Genet. 19:171-14
-
(1998)
Nat. Genet.
, vol.19
, pp. 171-214
-
-
Parkes, T.L.1
Elia, A.J.2
Dickinson, D.3
Hilliker, A.J.4
Phillips, J.P.5
Boulianne, G.L.6
-
112
-
-
0035063757
-
Evolutionary theories of ageing applied to long-lived organisms
-
Partridge L. 2001. Evolutionary theories of ageing applied to long-lived organisms. Exp. Gerontol. 36:641-50
-
(2001)
Exp. Gerontol.
, vol.36
, pp. 641-650
-
-
Partridge, L.1
-
113
-
-
0026452745
-
Direct and correlated responses to selection on age at reproduction in Drosophila melanogaster
-
Partridge L, Fowler K. 1992. Direct and correlated responses to selection on age at reproduction in Drosophila melanogaster. Evolution 46:76-91
-
(1992)
Evolution
, vol.46
, pp. 76-91
-
-
Partridge, L.1
Fowler, K.2
-
114
-
-
0036245337
-
Mechanisms of ageing: Public or private?
-
Partridge L, Gems D. 2002. Mechanisms of ageing: public or private? Nat. Rev. Genet. 3:165-75
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 165-175
-
-
Partridge, L.1
Gems, D.2
-
115
-
-
0033531345
-
Another set of responses and correlated responses to selection on age at reproduction in Drosophila melanogaster
-
Partridge L, Prowse N, Pignatelli P. 1999. Another set of responses and correlated responses to selection on age at reproduction in Drosophila melanogaster. Proc. R. Soc. London Ser. B 266:255-61
-
(1999)
Proc. R. Soc. London Ser. B
, vol.266
, pp. 255-261
-
-
Partridge, L.1
Prowse, N.2
Pignatelli, P.3
-
116
-
-
1542563727
-
The rate of free radical production as a determinant of the rate of aging: Evidence from the comparative approach
-
Perez-Campo R, Lopez-Torres M, Cadenas S, Rojas C, Barja G. 1998. The rate of free radical production as a determinant of the rate of aging: evidence from the comparative approach. Comp. Physiol. B 168:149-58
-
(1998)
Comp. Physiol. B
, vol.168
, pp. 149-158
-
-
Perez-Campo, R.1
Lopez-Torres, M.2
Cadenas, S.3
Rojas, C.4
Barja, G.5
-
117
-
-
0035339675
-
Rat peptide methionine sulphoxide reductase: Cloning of the cDNA, and down-regulation of gene expression and enzyme activity during aging
-
Petropoulos I, Mary J, Perichon M, Friguet B. 2001. Rat peptide methionine sulphoxide reductase: cloning of the cDNA, and down-regulation of gene expression and enzyme activity during aging. Biochem. J. 355:819-25
-
(2001)
Biochem. J.
, vol.355
, pp. 819-825
-
-
Petropoulos, I.1
Mary, J.2
Perichon, M.3
Friguet, B.4
-
118
-
-
0037197870
-
Genome-wide transcript profiles in aging and calorically restricted Drosophila melanogaster
-
Pletcher SD, Macdonald SJ, Marguerie R, Certa U, Stearns SC, et al. 2002. Genome-wide transcript profiles in aging and calorically restricted Drosophila melanogaster. Curr. Biol. 12:712-23
-
(2002)
Curr. Biol.
, vol.12
, pp. 712-723
-
-
Pletcher, S.D.1
Macdonald, S.J.2
Marguerie, R.3
Certa, U.4
Stearns, S.C.5
-
119
-
-
0026274237
-
Senescence in natural populations of mammals: A comparative study
-
Promislow DEL. 1991. Senescence in natural populations of mammals: a comparative study. Evolution 45:1869-87
-
(1991)
Evolution
, vol.45
, pp. 1869-1887
-
-
Promislow, D.E.L.1
-
120
-
-
0034306267
-
Mitochondria, oxygen free radicals, disease and ageing
-
Raha S, Robinson BH. 2000. Mitochondria, oxygen free radicals, disease and ageing. Trends Biochem. Sci. 25:502-8
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 502-508
-
-
Raha, S.1
Robinson, B.H.2
-
121
-
-
0031838418
-
Evolutionary theories of aging: Confirmation of a fundamental prediction, with implications for the genetic basis and evolution of life span
-
Ricklefs RE. 1998. Evolutionary theories of aging: confirmation of a fundamental prediction, with implications for the genetic basis and evolution of life span. Am. Nat. 152:24-44
-
(1998)
Am. Nat.
, vol.152
, pp. 24-44
-
-
Ricklefs, R.E.1
-
122
-
-
0030038257
-
Selection for longevity favors stringent metabolic control in Drosophila melanogaster
-
Riha V, Luckinbill L. 1996. Selection for longevity favors stringent metabolic control in Drosophila melanogaster. J. Gerontol. A 51:B284-94
-
(1996)
J. Gerontol. A
, vol.51
-
-
Riha, V.1
Luckinbill, L.2
-
123
-
-
18744416824
-
Longevity regulation by Drosophila Rpd3 deacetylase and caloric restriction
-
Rogina B, Helfand SL, Frankel S. 2002. Longevity regulation by Drosophila Rpd3 deacetylase and caloric restriction. Science 298:1745
-
(2002)
Science
, vol.298
, pp. 1745
-
-
Rogina, B.1
Helfand, S.L.2
Frankel, S.3
-
124
-
-
0034671596
-
Extended life-span conferred by cotransporter gene mutations in Drosophila
-
Rogina B, Reenan RA, Nilsen SP, Helfand SL. 2000. Extended life-span conferred by cotransporter gene mutations in Drosophila. Science 290:2137-40
-
(2000)
Science
, vol.290
, pp. 2137-2140
-
-
Rogina, B.1
Reenan, R.A.2
Nilsen, S.P.3
Helfand, S.L.4
-
125
-
-
0027380942
-
Evolutionary effects of selection on age at reproduction in larval and adult Drosophila melanogaster
-
Roper C, Pignatelli P, Partridge L. 1993. Evolutionary effects of selection on age at reproduction in larval and adult Drosophila melanogaster. Evolution 47:445-55
-
(1993)
Evolution
, vol.47
, pp. 445-455
-
-
Roper, C.1
Pignatelli, P.2
Partridge, L.3
-
126
-
-
0000977247
-
Laboratory evolution of postponed senescence in Drosophila melanogaster
-
Rose MR. 1984. Laboratory evolution of postponed senescence in Drosophila melanogaster. Evolution 38:1004-10
-
(1984)
Evolution
, vol.38
, pp. 1004-1010
-
-
Rose, M.R.1
-
128
-
-
0019191512
-
A test of evolutionary theories of senescence
-
Rose MR, Charlesworth B. 1980. A test of evolutionary theories of senescence. Nature 287:141-42
-
(1980)
Nature
, vol.287
, pp. 141-142
-
-
Rose, M.R.1
Charlesworth, B.2
-
129
-
-
0019346543
-
Genetics of life history in Drosophila melanogaster. 1. Sib analysis of adult females
-
Rose MR, Charlesworth B. 1981. Genetics of life history in Drosophila melanogaster. 1. Sib analysis of adult females. Genetics 97:173-86
-
(1981)
Genetics
, vol.97
, pp. 173-186
-
-
Rose, M.R.1
Charlesworth, B.2
-
130
-
-
0026684532
-
Selection on stress resistance increases longevity in Drosophila melanogaster
-
Rose MR, Vu LN, Park SU, Graves JLJ. 1992. Selection on stress resistance increases longevity in Drosophila melanogaster. Exp. Gerontol. 27:241-50
-
(1992)
Exp. Gerontol.
, vol.27
, pp. 241-250
-
-
Rose, M.R.1
Vu, L.N.2
Park, S.U.3
Graves, J.L.J.4
-
131
-
-
0037022556
-
High-quality life extension by the enzyme peptide methionine sulfoxide reductase
-
Ruan H, Tang XD, Chen M-L, Joiner M-LA, Sun G, et al. 2002. High-quality life extension by the enzyme peptide methionine sulfoxide reductase. Proc. Natl. Acad. Sci. USA 99:2748-53
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 2748-2753
-
-
Ruan, H.1
Tang, X.D.2
Chen, M.-L.3
Joiner, M.-L.A.4
Sun, G.5
-
132
-
-
0030272986
-
Chemosensory neurons function in parallel to mediate a pheromone response in C. elegans
-
Schackwitz WS, Inoue T, Thomas JH. 1996. Chemosensory neurons function in parallel to mediate a pheromone response in C. elegans. Neuron 17:719-28
-
(1996)
Neuron
, vol.17
, pp. 719-728
-
-
Schackwitz, W.S.1
Inoue, T.2
Thomas, J.H.3
-
134
-
-
0000247596
-
Resistance to environmental stress in Drosophila melanogaster selected for postponed senescence
-
Service PM, Hutchinson EW, Mackinley MD, Rose MR. 1985. Resistance to environmental stress in Drosophila melanogaster selected for postponed senescence. Physiol. Zool. 58:380-89
-
(1985)
Physiol. Zool.
, vol.58
, pp. 380-389
-
-
Service, P.M.1
Hutchinson, E.W.2
Mackinley, M.D.3
Rose, M.R.4
-
135
-
-
0000899365
-
Multiple genetic mechanisms for the evolution of senescence in Drosophila melanogaster
-
Service PM, Hutchison EW, Rose MR. 1988. Multiple genetic mechanisms for the evolution of senescence in Drosophila melanogaster. Evolution 42:708-16
-
(1988)
Evolution
, vol.42
, pp. 708-716
-
-
Service, P.M.1
Hutchison, E.W.2
Rose, M.R.3
-
136
-
-
0033601345
-
A delayed wave of death from reproduction in Drosophila
-
Sgro CM, Partridge L. 1999. A delayed wave of death from reproduction in Drosophila. Science 286:2521-24
-
(1999)
Science
, vol.286
, pp. 2521-2524
-
-
Sgro, C.M.1
Partridge, L.2
-
137
-
-
0000577267
-
A population in age distribution
-
Sharpe FR, Lotka AJ. 1911. A population in age distribution. Philos. Mag. 21:435-38
-
(1911)
Philos. Mag.
, vol.21
, pp. 435-438
-
-
Sharpe, F.R.1
Lotka, A.J.2
-
138
-
-
0038117292
-
Fruit flies with additional expression of the elongation factor EF-1 alpha live longer
-
133a. Shepherd JC, Walldorf U, Hug P, Gehring WJ. 1989. Fruit flies with additional expression of the elongation factor EF-1 alpha live longer. Proc. Natl. Acad. Sci. USA 86:7520-21
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 7520-7521
-
-
Shepherd, J.C.1
Walldorf, U.2
Hug, P.3
Gehring, W.J.4
-
139
-
-
12744273505
-
The molecular genetics of aging
-
ed. CE Finch, L Hayflick, New York: Van Nostrand Reinhold. 771 pp.
-
133b. Sinex FS. 1977. The molecular genetics of aging. In Handbook of the Biology of Aging, ed. CE Finch, L Hayflick, pp. 37-62, New York: Van Nostrand Reinhold. 771 pp.
-
(1977)
Handbook of the Biology of Aging
, pp. 37-62
-
-
Sinex, F.S.1
-
140
-
-
0348252202
-
Quantitative genetic tests of recent senescence theory: Age-specific mortality and male fertility in Drosophila melanogaster
-
Snoke MS, Promislow DEL. 2003. Quantitative genetic tests of recent senescence theory: age-specific mortality and male fertility in Drosophila melanogaster. Heredity 91:546-56
-
(2003)
Heredity
, vol.91
, pp. 546-556
-
-
Snoke, M.S.1
Promislow, D.E.L.2
-
141
-
-
0027235532
-
Aging, cytochrome oxidase activity, and hydrogen peroxide release by mitochondria
-
Sohal RS. 1993. Aging, cytochrome oxidase activity, and hydrogen peroxide release by mitochondria. Free Radic. Biol. Med. 14:583-88
-
(1993)
Free Radic. Biol. Med.
, vol.14
, pp. 583-588
-
-
Sohal, R.S.1
-
142
-
-
0029147191
-
Mitochondrial superoxide and hydrogen peroxide generation, protein oxidative damage, and longevity in different species of flies
-
Sohal RS, Sohal BH, Orr WC. 1995. Mitochondrial superoxide and hydrogen peroxide generation, protein oxidative damage, and longevity in different species of flies. Free Radic. Biol. Med. 19:499-504
-
(1995)
Free Radic. Biol. Med.
, vol.19
, pp. 499-504
-
-
Sohal, R.S.1
Sohal, B.H.2
Orr, W.C.3
-
143
-
-
0042422245
-
Testing an 'aging gene' in long-lived Drosophila strains: Increased longevity depends on sex and genetic background
-
Spencer CC, Howell CE, Wright AR, Promislow DEL. 2003. Testing an 'aging gene' in long-lived Drosophila strains: Increased longevity depends on sex and genetic background. Aging Cell 2:123-30
-
(2003)
Aging Cell
, vol.2
, pp. 123-130
-
-
Spencer, C.C.1
Howell, C.E.2
Wright, A.R.3
Promislow, D.E.L.4
-
144
-
-
0034724395
-
Experimental evolution of aging, growth, and reproduction in fruitflies
-
Stearns SC, Ackermann M, Doebeli M, Kaiser M. 2000. Experimental evolution of aging, growth, and reproduction in fruitflies. Proc. Natl. Acad. Sci. USA 97:3309-13
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 3309-3313
-
-
Stearns, S.C.1
Ackermann, M.2
Doebeli, M.3
Kaiser, M.4
-
145
-
-
2342548187
-
Effects of simultaneous over-expression of Cu/Zn SOD and MnSOd on Drosophila melanogaster life span
-
Sun J, Molitor J, Tower J. 2004. Effects of simultaneous over-expression of Cu/Zn SOD and MnSOd on Drosophila melanogaster life span. Mech. Ageing Dev. 125:341-49
-
(2004)
Mech. Ageing Dev.
, vol.125
, pp. 341-349
-
-
Sun, J.1
Molitor, J.2
Tower, J.3
-
146
-
-
0032908347
-
FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies
-
Sun JT, Tower J. 1999. FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies. Mol. Cell. Biol. 19:216-28
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 216-228
-
-
Sun, J.T.1
Tower, J.2
-
147
-
-
0035989388
-
Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster
-
Sun JT, Folk D, Bradley TJ, Tower J. 2002. Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster. Genetics 161:661-72
-
(2002)
Genetics
, vol.161
, pp. 661-672
-
-
Sun, J.T.1
Folk, D.2
Bradley, T.J.3
Tower, J.4
-
148
-
-
0028225368
-
Divergent roles of RAS1 and RAS2 in yeast longevity
-
Sun JY, Kale SP, Childress AM, Pinswasdi C, Jazwinski SM. 1994. Divergent roles of RAS1 and RAS2 in yeast longevity. J. Biol. Chem. 269:18638-45
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 18638-18645
-
-
Sun, J.Y.1
Kale, S.P.2
Childress, A.M.3
Pinswasdi, C.4
Jazwinski, S.M.5
-
149
-
-
0037470501
-
The endocrine regulation of aging by insulin-like signals
-
Tatar M, Bartke A, Antebi A. 2003. The endocrine regulation of aging by insulin-like signals. Science 299:1346-51
-
(2003)
Science
, vol.299
, pp. 1346-1351
-
-
Tatar, M.1
Bartke, A.2
Antebi, A.3
-
151
-
-
0035815445
-
A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function
-
Tatar M, Kopelman A, Epstein D, Tu MP, Yin CM, Garofalo RS. 2001. A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function. Science 292:107-10
-
(2001)
Science
, vol.292
, pp. 107-110
-
-
Tatar, M.1
Kopelman, A.2
Epstein, D.3
Tu, M.P.4
Yin, C.M.5
Garofalo, R.S.6
-
152
-
-
0027197284
-
Oxidative stress and ageing in Caenorhabditis elegans
-
Vanfleteren JR. 1993. Oxidative stress and ageing in Caenorhabditis elegans. Biochem. J. 292:605-8
-
(1993)
Biochem. J.
, vol.292
, pp. 605-608
-
-
Vanfleteren, J.R.1
-
155
-
-
0028826029
-
Muscle-specific expression of Drosophila hsp70 in response to aging and oxidative stress
-
Wheeler JC, Bieschke ET, Tower J. 1995. Muscle-specific expression of Drosophila hsp70 in response to aging and oxidative stress. Proc. Natl. Acad. Sci. USA 92:10408-12
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 10408-10412
-
-
Wheeler, J.C.1
Bieschke, E.T.2
Tower, J.3
-
156
-
-
0000055057
-
Pleitropy, natural selection, and the evolution of senescence
-
Williams GC. 1957. Pleitropy, natural selection, and the evolution of senescence. Evolution 11:398-411
-
(1957)
Evolution
, vol.11
, pp. 398-411
-
-
Williams, G.C.1
-
158
-
-
0034610286
-
Genome-wide study of aging and oxidative stress response in Drosophila melanogaster
-
Zou S, Meadows S, Sharp L, Jan LY, Jan YN. 2000. Genome-wide study of aging and oxidative stress response in Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 97:13726-31
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13726-13731
-
-
Zou, S.1
Meadows, S.2
Sharp, L.3
Jan, L.Y.4
Jan, Y.N.5
|