메뉴 건너뛰기




Volumn 168, Issue 3, 1998, Pages 149-158

The rate of free radical production as a determinant of the rate of aging: Evidence from the comparative approach

Author keywords

Aging; Free radical production Antioxidants; Maximum longevity; Mitochondria

Indexed keywords

ANTIOXIDANT; FREE RADICAL; HYDROGEN PEROXIDE;

EID: 1542563727     PISSN: 01741578     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003600050131     Document Type: Short Survey
Times cited : (318)

References (76)
  • 1
    • 0023988217 scopus 로고
    • Oxidative damage to DNA: Relation to species metabolic rate and life span
    • Adelman R, Saul RL, Ames BN (1988) Oxidative damage to DNA: relation to species metabolic rate and life span. Proc Natl Acad Sci USA 85: 2706-2708
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 2706-2708
    • Adelman, R.1    Saul, R.L.2    Ames, B.N.3
  • 2
    • 0026489605 scopus 로고
    • Isolation of a malondialdehyde-deoxyguanosine adduct from rat liver DNA
    • Agarwal S, Draper HH (1992) Isolation of a malondialdehyde-deoxyguanosine adduct from rat liver DNA. Free Rad Biol Med 13: 695-699
    • (1992) Free Rad Biol Med , vol.13 , pp. 695-699
    • Agarwal, S.1    Draper, H.H.2
  • 3
    • 0021105370 scopus 로고
    • Effect of catalase inactivation on levels of inorganic peroxides, superoxide dismutase, glutathione, oxygen consumption and life span in adult houseflies (Musca domestica)
    • Allen RG, Farmer KJ, Sohal RS (1983) Effect of catalase inactivation on levels of inorganic peroxides, superoxide dismutase, glutathione, oxygen consumption and life span in adult houseflies (Musca domestica). Biochem J 216: 503-506
    • (1983) Biochem J , vol.216 , pp. 503-506
    • Allen, R.G.1    Farmer, K.J.2    Sohal, R.S.3
  • 4
    • 0004416560 scopus 로고
    • DNA damage by endogenous oxidants and mitogenesis as causes of aging and cancer
    • Scandalios JG (ed) Cold Spring Harbor Laboratory Press, New York
    • Ames BN, Shigenaga MK (1992) DNA damage by endogenous oxidants and mitogenesis as causes of aging and cancer. In: Scandalios JG (ed) Molecular biology of free radical scavenging systems. Cold Spring Harbor Laboratory Press, New York, pp 1-22
    • (1992) Molecular Biology of Free Radical Scavenging Systems , pp. 1-22
    • Ames, B.N.1    Shigenaga, M.K.2
  • 6
    • 0025242056 scopus 로고
    • Antioxidant defenses and peroxidation in liver and brain of aged rats
    • Barja G, Pérez R, López M (1990) Antioxidant defenses and peroxidation in liver and brain of aged rats. Biochem J 272: 247-250
    • (1990) Biochem J , vol.272 , pp. 247-250
    • Barja, G.1    Pérez, R.2    López, M.3
  • 7
    • 0028001145 scopus 로고
    • A decrease of free radical production near critical targets as a cause of maximum longevity
    • Barja G, Cadenas S, Rojas C, López-Torres M, Pérez-Campo R (1994a) A decrease of free radical production near critical targets as a cause of maximum longevity. Comp Biochem Physiol 108B: 501-512
    • (1994) Comp Biochem Physiol , vol.108 B , pp. 501-512
    • Barja, G.1    Cadenas, S.2    Rojas, C.3    López-Torres, M.4    Pérez-Campo, R.5
  • 9
    • 0027034605 scopus 로고
    • Relationship between antioxidants, lipid peroxidation and aging
    • Emerit I, Chance B (eds). Birkhäuser, Basel
    • Barja de Quiroga G, López-Torres M, Pérez-Campo R (1992) Relationship between antioxidants, lipid peroxidation and aging. In: Emerit I, Chance B (eds) Free radicals and aging. Birkhäuser, Basel, pp 109-123
    • (1992) Free Radicals and Aging , pp. 109-123
    • Barja De Quiroga, G.1    López-Torres, M.2    Pérez-Campo, R.3
  • 10
    • 0029012812 scopus 로고
    • Age- and peroxidative stress-related modifications of the cerebral enzymatic activities linked to mitochondria and the glutathione system
    • Benzi G, Moretti A (1995) Age-and peroxidative stress-related modifications of the cerebral enzymatic activities linked to mitochondria and the glutathione system. Free Rad Biol Med 19: 77-101
    • (1995) Free Rad Biol Med , vol.19 , pp. 77-101
    • Benzi, G.1    Moretti, A.2
  • 11
    • 0026969362 scopus 로고
    • Poly(ADP-ribosyl)ation: Its role in inducible DNA amplification, and its correlation with the longevity of mammalian species
    • Bürkle A, Grube K, Küpper JH (1992) Poly(ADP-ribosyl)ation: its role in inducible DNA amplification, and its correlation with the longevity of mammalian species. Exp Clin Immunogenet 9: 230-240
    • (1992) Exp Clin Immunogenet , vol.9 , pp. 230-240
    • Bürkle, A.1    Grube, K.2    Küpper, J.H.3
  • 12
    • 0021972585 scopus 로고
    • The comparative biology of longevity and lifetime energetics
    • Calder WA (1985) The comparative biology of longevity and lifetime energetics. Exp Gerontol 20: 161-170
    • (1985) Exp Gerontol , vol.20 , pp. 161-170
    • Calder, W.A.1
  • 13
    • 0026592966 scopus 로고
    • 8-hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions
    • Cheng KC, Cahill DS, Kasai H, Nishimura S, Loeb LA (1992) 8-hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions. J Biol Chem 267: 166-172
    • (1992) J Biol Chem , vol.267 , pp. 166-172
    • Cheng, K.C.1    Cahill, D.S.2    Kasai, H.3    Nishimura, S.4    Loeb, L.A.5
  • 15
    • 0015235791 scopus 로고
    • Effects of ethoxyquin on the longevity of C3H mice
    • Comfort A (1971) Effects of ethoxyquin on the longevity of C3H mice. Nature 229: 254-255
    • (1971) Nature , vol.229 , pp. 254-255
    • Comfort, A.1
  • 16
    • 0000098878 scopus 로고
    • Antioxidants aging and longevity
    • Pryor WA (ed) Academic Press, New York
    • Cutler RG (1984a) Antioxidants aging and longevity. In: Pryor WA (ed) Free radicals in biology, vol VI. Academic Press, New York, pp 371-428
    • (1984) Free Radicals in Biology , vol.6 , pp. 371-428
    • Cutler, R.G.1
  • 17
    • 0021675169 scopus 로고
    • Urate and ascorbate: Their possible roles as antioxidants in determining longevity of mammalian species
    • Cutler RG (1984b) Urate and ascorbate: their possible roles as antioxidants in determining longevity of mammalian species. Arch Gerontol Geriatr 3: 321-348
    • (1984) Arch Gerontol Geriatr , vol.3 , pp. 321-348
    • Cutler, R.G.1
  • 18
    • 0021777459 scopus 로고
    • Antioxidants and longevity of mammalian species
    • Woodhead AD, Blackett AD, Hollaender A (eds) Plenum, New York
    • Cutler RG (1985) Antioxidants and longevity of mammalian species. In: Woodhead AD, Blackett AD, Hollaender A (eds) Molecular biology of aging. Plenum, New York, pp 15-73
    • (1985) Molecular Biology of Aging , pp. 15-73
    • Cutler, R.G.1
  • 19
    • 0002389290 scopus 로고
    • Aging and oxygen radicals
    • Taylor AE, Matalon S, Ward P (eds) American Physiological Society, Bethesda
    • Cutler RG (1986) Aging and oxygen radicals. In: Taylor AE, Matalon S, Ward P (eds) Physiology of oxygen radicals. American Physiological Society, Bethesda, pp 251-285
    • (1986) Physiology of Oxygen Radicals , pp. 251-285
    • Cutler, R.G.1
  • 20
    • 0026008160 scopus 로고
    • Antioxidants and aging
    • Cutler RG (1991) Antioxidants and aging. Am J Clin Nutr 53: 373S-379S
    • (1991) Am J Clin Nutr , vol.53
    • Cutler, R.G.1
  • 22
    • 0029919108 scopus 로고    scopus 로고
    • Age-associated mitochondrial DNA deletions in mouse skeletal muscle: Comparison of different regions of the mitochondrial genome
    • Eimon PM, Chung SS, Lee CM, Weindruch R, Aiken JM (1996) Age-associated mitochondrial DNA deletions in mouse skeletal muscle: comparison of different regions of the mitochondrial genome. Dev Genet 18: 107-113
    • (1996) Dev Genet , vol.18 , pp. 107-113
    • Eimon, P.M.1    Chung, S.S.2    Lee, C.M.3    Weindruch, R.4    Aiken, J.M.5
  • 23
  • 24
    • 0025373259 scopus 로고
    • Oxidative damage to DNA during aging: 8-hydroxy-2′-deoxyguanosine in rat organ DNA and urine
    • Fraga CG, Shigenaga MK, Park JW, Degan P, Ames BN (1990) Oxidative damage to DNA during aging: 8-hydroxy-2′-deoxyguanosine in rat organ DNA and urine. Proc Natl Acad Sci USA 87: 4533-4537
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4533-4537
    • Fraga, C.G.1    Shigenaga, M.K.2    Park, J.W.3    Degan, P.4    Ames, B.N.5
  • 25
    • 0019723825 scopus 로고
    • The relationship of DNA excision repair of ultraviolet-induced lesions to the maximum life span of mammals
    • Francis AA, Lee WH, Regan JD (1981) The relationship of DNA excision repair of ultraviolet-induced lesions to the maximum life span of mammals. Mech Ageing Dev 16: 181-189
    • (1981) Mech Ageing Dev , vol.16 , pp. 181-189
    • Francis, A.A.1    Lee, W.H.2    Regan, J.D.3
  • 26
    • 0021321375 scopus 로고
    • Correlation between ultraviolet-induced DNA repair in primate lymphocytes and fibroblasts and species maximum achievable longevity
    • Hall KY, Hart RW, Benirschke AK, Walford RL (1984) Correlation between ultraviolet-induced DNA repair in primate lymphocytes and fibroblasts and species maximum achievable longevity. Mech Ageing Dev 24: 164-173
    • (1984) Mech Ageing Dev , vol.24 , pp. 164-173
    • Hall, K.Y.1    Hart, R.W.2    Benirschke, A.K.3    Walford, R.L.4
  • 28
    • 0014340640 scopus 로고
    • Free radical theory of aging: Effect of free radical inhibitors on the mortality rate of male LAF1 mice
    • Harman D (1968) Free radical theory of aging: effect of free radical inhibitors on the mortality rate of male LAF1 mice. J Gerontol 23: 476-482
    • (1968) J Gerontol , vol.23 , pp. 476-482
    • Harman, D.1
  • 29
    • 0015319592 scopus 로고
    • The biological clock: The mitochondria?
    • Harman D (1972) The biological clock: the mitochondria? J Am Geriatr Soc 20: 145-147
    • (1972) J Am Geriatr Soc , vol.20 , pp. 145-147
    • Harman, D.1
  • 30
    • 0011555560 scopus 로고
    • Correlation between deoxyribonucleic acid excision-repair and life-span in a number of mammalian species
    • Hart RW, Setlow RB (1974) Correlation between deoxyribonucleic acid excision-repair and life-span in a number of mammalian species. Proc Natl Acad Sci USA 71: 2169-2173
    • (1974) Proc Natl Acad Sci USA , vol.71 , pp. 2169-2173
    • Hart, R.W.1    Setlow, R.B.2
  • 31
    • 0022362448 scopus 로고
    • Theories of biological aging
    • Hayflick L (1985) Theories of biological aging. Exp Gerontol 20: 145-159
    • (1985) Exp Gerontol , vol.20 , pp. 145-159
    • Hayflick, L.1
  • 32
    • 0030793931 scopus 로고    scopus 로고
    • Sites and mechanisms responsible for the low rate of free radical production of heart mitochondria in the long-lived pigeon
    • Herrero A, Barja G (1997a) Sites and mechanisms responsible for the low rate of free radical production of heart mitochondria in the long-lived pigeon. Mech Ageing Dev 98: 95-111
    • (1997) Mech Ageing Dev , vol.98 , pp. 95-111
    • Herrero, A.1    Barja, G.2
  • 33
    • 0030874890 scopus 로고    scopus 로고
    • ADP regulation of mitochondrial free radical production is different with Complex I- or Complex II-linked substrates: Implications for the exercise paradox and brain hypermetabolism
    • Herrero A, Barja G (1997b) ADP regulation of mitochondrial free radical production is different with Complex I-or Complex II-linked substrates: implications for the exercise paradox and brain hypermetabolism. J Bioenerg Biomembr 29: 243-251
    • (1997) J Bioenerg Biomembr , vol.29 , pp. 243-251
    • Herrero, A.1    Barja, G.2
  • 34
    • 0029520541 scopus 로고
    • The evolution of avian senescence patterns; implications for understanding primary aging processes
    • Holmes DJ, Austad SN (1995) The evolution of avian senescence patterns; implications for understanding primary aging processes. Am Zool 35: 307-317
    • (1995) Am Zool , vol.35 , pp. 307-317
    • Holmes, D.J.1    Austad, S.N.2
  • 35
    • 0025346328 scopus 로고
    • The 8-hydroxyguanine content of isolated mitochondria increases with lipid peroxidation
    • Hruszkewycz AM, Bergtold DS (1990) The 8-hydroxyguanine content of isolated mitochondria increases with lipid peroxidation. Mutat Res 244: 123-128
    • (1990) Mutat Res , vol.244 , pp. 123-128
    • Hruszkewycz, A.M.1    Bergtold, D.S.2
  • 36
    • 0030016821 scopus 로고    scopus 로고
    • Longevity, genes, and aging
    • Jazwinski SM (1996) Longevity, genes, and aging. Science 273: 54-59
    • (1996) Science , vol.273 , pp. 54-59
    • Jazwinski, S.M.1
  • 37
    • 0023109386 scopus 로고
    • Influences of dietary restriction and age on liver enzymatic activities and lipid peroxidation in mice
    • Koizumi A, Weindruch R, Walford RL (1987) Influences of dietary restriction and age on liver enzymatic activities and lipid peroxidation in mice. J Nutr 117: 361-367
    • (1987) J Nutr , vol.117 , pp. 361-367
    • Koizumi, A.1    Weindruch, R.2    Walford, R.L.3
  • 38
    • 0027517591 scopus 로고
    • Comparison of mitochondrial pro-oxidant generation and antioxidant defenses between rat and pigeon: Possible basis of variation in longevity and metabolic potential
    • Ku HH, Sohal RS (1993) Comparison of mitochondrial pro-oxidant generation and antioxidant defenses between rat and pigeon: possible basis of variation in longevity and metabolic potential. Mech Ageing Dev 72: 67-76
    • (1993) Mech Ageing Dev , vol.72 , pp. 67-76
    • Ku, H.H.1    Sohal, R.S.2
  • 39
    • 0027365312 scopus 로고
    • Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species
    • Ku HH, Brunk UT, Sohal RS (1993) Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species. Free Rad Biol Med 15: 621-627
    • (1993) Free Rad Biol Med , vol.15 , pp. 621-627
    • Ku, H.H.1    Brunk, U.T.2    Sohal, R.S.3
  • 40
    • 0030447280 scopus 로고    scopus 로고
    • Human senescence
    • Kirkwood TBL (1996) Human senescence. Bioessays 18: 1009-1016
    • (1996) Bioessays , vol.18 , pp. 1009-1016
    • Kirkwood, T.B.L.1
  • 41
    • 0028175532 scopus 로고
    • Sensitivity of mitochondrial transcription to different free radical species
    • Kristal BS, Chen J, Yu BP (1994) Sensitivity of mitochondrial transcription to different free radical species. Free Rad Biol Med 16: 323-329
    • (1994) Free Rad Biol Med , vol.16 , pp. 323-329
    • Kristal, B.S.1    Chen, J.2    Yu, B.P.3
  • 42
    • 0018240723 scopus 로고
    • Species, tissue and subcellular distribution of non-Se dependent glutathione peroxidase activity
    • Lawrence A, Burk RF (1978) Species, tissue and subcellular distribution of non-Se dependent glutathione peroxidase activity. J Nutr 108: 211-215
    • (1978) J Nutr , vol.108 , pp. 211-215
    • Lawrence, A.1    Burk, R.F.2
  • 44
    • 0027326740 scopus 로고
    • Simultaneous induction of superoxide dismutase, glutathione reductase, GSH and ascorbate in liver and kidney correlates with survival throughout the life span
    • López-Torres M, Pérez-Campo R, Rojas C, Cadenas S, Barja de Quiroga G (1993b) Simultaneous induction of superoxide dismutase, glutathione reductase, GSH and ascorbate in liver and kidney correlates with survival throughout the life span. Free Rad Biol Med 15: 133-142
    • (1993) Free Rad Biol Med , vol.15 , pp. 133-142
    • López-Torres, M.1    Pérez-Campo, R.2    Rojas, C.3    Cadenas, S.4    Barja De Quiroga, G.5
  • 45
    • 0027531428 scopus 로고
    • Brain glutathione reductase induction increases early survival and decreases lipofuscin accumulation in aging frogs
    • López-Torres M, Pérez-Campo R, Fernandez A, Barba C, Barja de Quiroga G (1993e) Brain glutathione reductase induction increases early survival and decreases lipofuscin accumulation in aging frogs. J Neurosci Res 34: 233-242
    • (1993) J Neurosci Res , vol.34 , pp. 233-242
    • López-Torres, M.1    Pérez-Campo, R.2    Fernandez, A.3    Barba, C.4    Barja De Quiroga, G.5
  • 46
    • 0029920370 scopus 로고    scopus 로고
    • Genetic analysis of ageing: Role of oxidative damage and environmental stresses
    • Martin GM, Austad SN, Johnson TE (1996) Genetic analysis of ageing: role of oxidative damage and environmental stresses. Nature Genet 13: 25-34
    • (1996) Nature Genet , vol.13 , pp. 25-34
    • Martin, G.M.1    Austad, S.N.2    Johnson, T.E.3
  • 47
    • 0025344161 scopus 로고
    • Age-dependent production of mitochondrial hydrogen peroxide, lipid peroxides and fluorescent pigments in rat heart
    • Muscari C, Caladrera CM, Guarnieri C (1990) Age-dependent production of mitochondrial hydrogen peroxide, lipid peroxides and fluorescent pigments in rat heart. Basic Res Cardiol 85: 172-178
    • (1990) Basic Res Cardiol , vol.85 , pp. 172-178
    • Muscari, C.1    Caladrera, C.M.2    Guarnieri, C.3
  • 48
    • 0026783733 scopus 로고
    • The effects of catalase gene overexpression on life span and resistance to oxidative stress in transgenic Drosophila melanogaster
    • Orr WC, Sohal RS (1992) The effects of catalase gene overexpression on life span and resistance to oxidative stress in transgenic Drosophila melanogaster. Arch Biochem Biophys 297: 35-41
    • (1992) Arch Biochem Biophys , vol.297 , pp. 35-41
    • Orr, W.C.1    Sohal, R.S.2
  • 49
    • 0028220114 scopus 로고
    • Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster
    • Orr WC, Sohal RS (1994) Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science 263: 1128-1130
    • (1994) Science , vol.263 , pp. 1128-1130
    • Orr, W.C.1    Sohal, R.S.2
  • 50
    • 0029010616 scopus 로고
    • Mitochondrial DNA mutations associated with aging and degenerative diseases
    • Ozawa T (1995) Mitochondrial DNA mutations associated with aging and degenerative diseases. Exp Gerontol 30: 269-290
    • (1995) Exp Gerontol , vol.30 , pp. 269-290
    • Ozawa, T.1
  • 51
    • 0020079301 scopus 로고
    • Inverse correlation between species life span and specific cytochrome P-448 content of cultured fibroblasts
    • Pashko LL, Schwartz AG (1982) Inverse correlation between species life span and specific cytochrome P-448 content of cultured fibroblasts. J Gerontol 37: 38-41
    • (1982) J Gerontol , vol.37 , pp. 38-41
    • Pashko, L.L.1    Schwartz, A.G.2
  • 52
    • 0003693103 scopus 로고
    • University of London Press, London
    • Pearl R (1928) The rate of living. University of London Press, London
    • (1928) The Rate of Living
    • Pearl, R.1
  • 53
    • 0026032113 scopus 로고
    • Aging and lung antioxidant enzymes, glutathione, and lipid peroxidation in the rat
    • Pérez R, López M, Barja de Quiroga G (1991) Aging and lung antioxidant enzymes, glutathione, and lipid peroxidation in the rat. Free Rad Biol Med 10: 35-39
    • (1991) Free Rad Biol Med , vol.10 , pp. 35-39
    • Pérez, R.1    López, M.2    Barja De Quiroga, G.3
  • 55
    • 0027320064 scopus 로고
    • Life span in birds and the ageing theory of absolute metabolic scope
    • Prinzinger R (1993) Life span in birds and the ageing theory of absolute metabolic scope. Comp Biochem Physiol 105A: 609-615
    • (1993) Comp Biochem Physiol , vol.105 A , pp. 609-615
    • Prinzinger, R.1
  • 56
    • 0028190820 scopus 로고
    • Role of mitochondrial DNA modifications in degenerative diseases and aging
    • Richter C (1995) Role of mitochondrial DNA modifications in degenerative diseases and aging. Curr Topics Bioenerg 17: 1-19
    • (1995) Curr Topics Bioenerg , vol.17 , pp. 1-19
    • Richter, C.1
  • 57
    • 0023811053 scopus 로고
    • Normal oxidative damage to mitochondrial and nuclear DNA is extensive
    • Richter C, Park JW, Ames BN (1988) Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proc Natl Acad Sci 85: 6465-6467
    • (1988) Proc Natl Acad Sci , vol.85 , pp. 6465-6467
    • Richter, C.1    Park, J.W.2    Ames, B.N.3
  • 61
    • 0025362247 scopus 로고
    • Overexpression of Cu-Zn superoxide dismutase in Drosophila does not affect life-span
    • Seto NOL, Hayashi S, Tener GM (1990) Overexpression of Cu-Zn superoxide dismutase in Drosophila does not affect life-span. Proc Natl Acad Sci USA 87: 4270-4274
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4270-4274
    • Seto, N.O.L.1    Hayashi, S.2    Tener, G.M.3
  • 62
    • 0017728103 scopus 로고
    • DNa replication by a membrane-DNa complex from rat liver mitochondria
    • Shearman CW, Kalf GF (1977) DNA replication by a membrane-DNA complex from rat liver mitochondria. Arch Biochem Biophys 182: 573-586
    • (1977) Arch Biochem Biophys , vol.182 , pp. 573-586
    • Shearman, C.W.1    Kalf, G.F.2
  • 63
    • 0025981359 scopus 로고
    • Insertion of specific bases during the synthesis past the oxidation-damaged base 8-oxo-dG
    • Shibutani S, Takeshita M, Grollman P (1991) Insertion of specific bases during the synthesis past the oxidation-damaged base 8-oxo-dG. Nature 349: 431-434
    • (1991) Nature , vol.349 , pp. 431-434
    • Shibutani, S.1    Takeshita, M.2    Grollman, P.3
  • 64
    • 0030038103 scopus 로고    scopus 로고
    • Oxidative stress, caloric restriction, and aging
    • Sohal RS, Weindruch R (1996) Oxidative stress, caloric restriction, and aging. Science 273: 59-63
    • (1996) Science , vol.273 , pp. 59-63
    • Sohal, R.S.1    Weindruch, R.2
  • 66
    • 0025363588 scopus 로고
    • Hydrogen peroxide production by liver mitochondria in different species
    • Sohal RS, Svensson I, Brunk UT (1990) Hydrogen peroxide production by liver mitochondria in different species. Mech Ageing Dev 53: 209-215
    • (1990) Mech Ageing Dev , vol.53 , pp. 209-215
    • Sohal, R.S.1    Svensson, I.2    Brunk, U.T.3
  • 67
    • 0028342438 scopus 로고
    • Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse
    • Sohal RS, Ku HK, Agarwal S, Forster MJ, Lal H (1994) Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse. Mech Ageing Dev 74: 121-133
    • (1994) Mech Ageing Dev , vol.74 , pp. 121-133
    • Sohal, R.S.1    Ku, H.K.2    Agarwal, S.3    Forster, M.J.4    Lal, H.5
  • 68
    • 0025681888 scopus 로고
    • Phenotypic consequences of copper-zinc superoxide dismutase overexpression in Drosophila melanogaster
    • Staveley BE, Phillips JP, Hilliker A (1990) Phenotypic consequences of copper-zinc superoxide dismutase overexpression in Drosophila melanogaster. Genome 33: 867-872
    • (1990) Genome , vol.33 , pp. 867-872
    • Staveley, B.E.1    Phillips, J.P.2    Hilliker, A.3
  • 69
    • 0019413794 scopus 로고
    • Hepatic glutathione S-transferases: Activities and cellular localization in rat, rhesus monkey, chimpanzee and man
    • Summer KH, Greim H (1981) Hepatic glutathione S-transferases: activities and cellular localization in rat, rhesus monkey, chimpanzee and man. Biochem Pharmacol 30: 1719-1720
    • (1981) Biochem Pharmacol , vol.30 , pp. 1719-1720
    • Summer, K.H.1    Greim, H.2
  • 70
    • 0842331263 scopus 로고
    • Superoxide dismutase: Correlation with life-span and specific metabolic rate in primate species
    • Tolmasoff JM, Ono T, Cutler RG (1980) Superoxide dismutase: correlation with life-span and specific metabolic rate in primate species. Proc Natl Acad Sci USA 77: 2777-2781
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 2777-2781
    • Tolmasoff, J.M.1    Ono, T.2    Cutler, R.G.3
  • 71
    • 0027017697 scopus 로고
    • Effect of aging on glutathione metabolism. Protection by antioxidants
    • Emerit I, Chance B (eds) Birkhäuser, Basel
    • Viña J, Sastre J, Antón V, Bruseghini L, Esteras A, Asensi M (1992) Effect of aging on glutathione metabolism. Protection by antioxidants. In: Emerit I, Chance B (eds) Free radicals and aging. Birkhäuser, Basel, pp 136-144
    • (1992) Free Radicals and Aging , pp. 136-144
    • Viña, J.1    Sastre, J.2    Antón, V.3    Bruseghini, L.4    Esteras, A.5    Asensi, M.6
  • 72
    • 0026587335 scopus 로고
    • Mitochondrial genetics: A paradigm for aging and degenerative diseases
    • Wallace DC (1992) Mitochondrial genetics: a paradigm for aging and degenerative diseases. Science 256: 628-632
    • (1992) Science , vol.256 , pp. 628-632
    • Wallace, D.C.1
  • 73
    • 0020044308 scopus 로고
    • Dietary restriction in mice at 1 year of age: Effect on life-span and spontaneous cancer incidence
    • Weindruch R, Walford RL (1982) Dietary restriction in mice at 1 year of age: effect on life-span and spontaneous cancer incidence. Science 215: 1415-1418
    • (1982) Science , vol.215 , pp. 1415-1418
    • Weindruch, R.1    Walford, R.L.2
  • 74
    • 0027512399 scopus 로고
    • Cellular mechanisms of biological aging
    • Yu BP (1993) Cellular mechanisms of biological aging. Phytother Res 7: S57-S59
    • (1993) Phytother Res , vol.7
    • Yu, B.P.1
  • 75
    • 0001099883 scopus 로고
    • Modulation of oxidative stress as a means of life-prolonging action of dietary restriction
    • Cutler RG, Packer L, Bertram J, Mori A (eds) Birkhäuser, Basel
    • Yu BP (1995) Modulation of oxidative stress as a means of life-prolonging action of dietary restriction. In: Cutler RG, Packer L, Bertram J, Mori A (eds) Oxidative stress and aging. Birkhäuser, Basel, pp 331-342
    • (1995) Oxidative Stress and Aging , pp. 331-342
    • Yu, B.P.1
  • 76
    • 0026542892 scopus 로고
    • Age-related change of free radical generation in liver and sex glands of rats
    • Zhan H, Sun CP, Liu CG, Zhou JH (1992) Age-related change of free radical generation in liver and sex glands of rats. Mech Ageing Dev 62: 111-116
    • (1992) Mech Ageing Dev , vol.62 , pp. 111-116
    • Zhan, H.1    Sun, C.P.2    Liu, C.G.3    Zhou, J.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.