Forward and reverse selection for longevity in Drosophila is characterized by alteration of antioxidant gene expression and oxidative damage patterns

Experimental Gerontology

Volumn 35, Issue 2, 2000, Pages 167-185

  Arking, Robert ^a   Burde, Vasanti ^a   Graves, Kevin ^a   Hari, Raj ^a   Feldman, Elliot ^a   Zeevi, Aaron ^a   Soliman, Sherif ^a   Saraiya, Ashesh ^a   Buck, Steven ^a   Vettraino, John ^a   Sathrasala, Kalpana ^a   Wehr, Nancy ^b   Levine, Rodney L ^b  

^a WAYNE STATE UNIVERSITY   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

Antioxidant genes; Catalase; CuZnSOD; Drosophila; Gene expression; Longevity; MnSOD; Oxidative damage; Selection

Indexed keywords

ANTIOXIDANT; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; MANGANESE SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DROSOPHILA; DROSOPHILA MELANOGASTER; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; LIPID PEROXIDATION; LONGEVITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; STRAIN DIFFERENCE;

ACATALASIA; ANIMALS; CATALASE; DROSOPHILA; GENE EXPRESSION; LONGEVITY; OXIDATION-REDUCTION; OXIDOREDUCTASES; RNA, MESSENGER; SELECTION (GENETICS); SUPEROXIDE DISMUTASE;

DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 0034032863     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0531-5565(99)00094-7     Document Type: Article

References (49)

1. Arking R. Successful selection for increased longevity in Drosophila analysis of the survival data and presentation of a hypothesis on the genetic regulation of longevity . Exp Gerontol. 22:1987;199-220.
2. Arking R. Molecular basis of extended longevity in selected Drosophila strains. Curr Science. 74:1998;859-864.
3. Arking R., Buck S. Selection for increased longevity in Drosophila melanogaster A reply to Lints . Gerontology. 41:1995;69-76.
4. Arking R., Buck S., Berrios A., Dwyer S., Baker G.T. III. Elevated antioxidant activity can be used as a bioassay for longevity in a genetically based long-lived strain of Drosophila. Develop Genetics. 12:1991;362-370.
5. Arking, R., Buck, S., Wells, R. A., & Pretzlaff, R. (1988). Metabolic rates in genetically based long-lived strains of Drosophila. Exp Gerontol 23, 59-76.
6. Arking R., Force A.G., Dudas S.P., Buck S., Baker G.T. III. Factors contributing to the plasticity of the extended longevity phenotypes of Drosophila. Exp Gerontol. 31:1996;623-643.
7. Arking R., Wells R.A. Genetic alteration of normal aging processes is responsible for extended longevity in Drosophila. Develop Genetics. 11:1990;141-148.
8. Ausabel, F. M., Brent, R., Kingston, R., Moore, D., Seidman, J.G., Smith, J.A., & Struhl, K. (1992). Short Protocols in Molecular Biology, 2nd ed. New York: John Wiley and Sons.
9. Buck S., Wells R.A., Dudas S.P., Baker G.T. III, Arking R. Chromosomal localization and regulation of the longevity determinant genes in a selected strain of Drosophila melanogaster. Heredity. 71:1993;11-22.
10. Chefurka, W. (1965). Intermediary metabolism of carbohydrates in insects. In M. Rockstein (Ed.). The Physiology of Insecta, Vol. II (pp. 669-768). New York: Academic Press.
11. Clark A.G., Wang L., Hulleberg T. P-element induced variation in metabolic regulation in Drosophila. Genetics. 139:1995;337-348.
12. Curtsinger, J. (1998). Quantitative trait loci mapping and cloning of longevity assurance genes in Drosophila (abstr.). Talk given at GSA national meeting, Philadelphia, PA, Nov. 22 1998. The Gerontologist 38 (special issue):92;and personal communication.
13. Curtsinger J.W., Fukui H.H., Resler A.S., Kelly K., Khazaeli A.A. Genetic analysis of extended life spans in Drosophila melanogaster. I. RAPD screen for genetic divergence between selected and control lines. Genetica. 104:1998;21-32.
14. da Cunha G.L., de Oliveira A.K. Citric acid cycle A mainstream metabolic pathway influencing life span in Drosophila melanogaster? Exp Gerontol. 31:1996;705-715.
15. Djawdan M., Chippendale A.K., Rose M.R., Bradley T.J. Metabolic reserves and evolved stress resistance in Drosophila melanogaster. Physiol Zool. 71:1998;584-594.
16. Dudas S.P., Arking R. A coordinate upregulation of antioxidant gene activities is associated with the delayed onset of senescence in a long-lived strain of Drosophila. J Gerontol: Biol Sci. 50A:1995;B117-B127.
17. Feuers R.J., Duffy P.H., Chen F., Desai V., Oriaku E., Shaddock J.G., Pipkin J.W., Weindruch R., Hart R.W. Intermediary metabolism and antioxidant systems. Hart R.W., Neumann D.A., Robertson R.T. Dietary Restriction, Implications for the Design and Interpretation of Toxicity, and Carcinogenicity Studies (pp. 1995;181-196 ILSI Press, Washington, DC.
18. Fleming J.E., Spicer G.S., Garrison R.C., Rose M.R. Two-dimensional protein electrophoretic analysis of postponed aging in Drosophila. Rose M.R., Finch C.E. Genetics and Evolution of Aging (pp. 1993;199-214 Kluwer Academic Publishers, Dordrecht, The Netherlands.
19. Force A.G., Staples T., Soliman S., Arking R. Comparative biochemical and stress analysis of genetically selected Drosophila strains with different longevities. Develop Genetics. 17:1995;340-351.
20. Goth L. A simple method for determination of serum catalase activity and revision of reference range. Clin Chim Acta. 196:1991;143-151.
21. Graves J.L., Luckinbill L.S., Nichols A. Flight duration and wing beat frequency in long- and short- lived Drosophila melanogaster. J Insect Physiol. 34:1988;1021-1026.
22. Hari R., Burde V., Arking R. Preparation of a synthetic antibody specific for CuZnSuperoxide Dismutase protein of Drosophila melanogaster. Exp Gerontol. 33:1998;227-237.
23. Harmon D. Aging a theory based on free radical and radiation chemistry . J Gerontol. 11:1956;298-300.
24. Harp W.L. Statistics for Psychologists. 1963;Holt, Rinehart and Winston, New York.
25. Harris H., Hopkinson D.A. Handbook of Enzyme Electrophoresis in Human Genetics (Suppl.). 1978;North-Holland Publishing Co, Amsterdam.
26. Johnson, T.E., Lithgow, G.J., & Murakami, S. (1996). Hypothesis: interventions that increase the response to stress after the potential for effective life prolongation and increased health. J Gerontol Biol Sci 51A, B392-B395.
27. Keppel, G. & Zedek, S. (1985). Data analysis for research designs: analysis of variance and multiple regression/correlation approaches. New York: W. H. Freeman and Company.
28. Lindsley D.L., Zimm G.G. The Genome of Drosophila Melanogaster. 1992;Academic Press, San Diego.
29. Levine, R. L., Williams, J. A., Stadtman, E. R., & Schacter, E. (1994). Methods in Enzymology 233, 346-357.
30. Luckinbill, L. S., Arking, R., Clare, M. J., Cirocco. W. C., & Buck, S. (1984). Selection for delayed senescence in Drosophila melanogaster. Evolution 38, 996-1004.
31. Luckinbill L.S., Riha V., Rhine S., Grudzien T.A. The role of glucose-6-phosphate in the evolution of longevity in Drosophila melanogaster. Heredity. 65:1990;29-38.
32. Martin G.M., Austad S.N., Johnson T.E. Genetic analysis of ageing role of oxidative damage and environmental stresses . Nature Genet. 13:1996;25-34.
33. Misra H.P., Fridovitch I. The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem. 256:1972;8506-8509.
34. Nudzhin S.V., Pasyukova E.G., Dilda C.L., Zeng Z.-B., Mackay T.F.C. Sex specific quantitative trait loci affecting longevity in Drosophila melanogaster. Proc Natl Acad Sci USA. 94:1997;9734-9739.
35. Orr W.C., Sohal R.S. Extension of life-span by over expression of superoxide dismutase and catalase in Drosophila melanogaster. Science. 263:1994;1128-1130.
36. Parkes T.L., Elia A.J., Dickinson D., Hilliker A.J., Phillips J.P., Boulianne G.L. Extension of Drosophila lifespan by over expression of human SOD1 in motorneurons. Nature Genet. 19:1998;171-174.
37. Parsons P.A. Inherited stress resistance and longevity a stress theory of ageing . Heredity. 75:1995;216-221.
38. Pierce J., Suelter C.H. An evaluation of the Coomassie brilliant blue G-250 dye binding method for quantitative protein determination. Anal Biochem. 81:1977;478-480.
39. Resler A.S., Kelly K., Kantor G., Khazaeli A.A., Tatar M., Curtsinger J.W. Genetic analysis of extended life spans in Drosophila melanogaster. II. Replication of the backcross test and molecular characterization of the N14 locus. Genetica. 104:1998;33-39.
40. Riha V.F., Luckinbill L.S. Selection for longevity favors stringent metabolic control in Drosophila melanogaster. J Gerontol: Biol Sci. 51:1996;B284-B294.
41. Sohal R.J., Agarwal S., Dubey A., Orr W.C. Protein oxidative damage is associated with life expectancy of houseflies. Proc Natl Acad Sci USA. 90:1993;7255-7259.
42. Sohal R.J., Weindruch R. Oxidative stress, caloric restriction, and aging. Science. 273:1996;59-63.
43. Stadtman E. Protein oxidation and aging. Science. 257:1992;1220-1224.
44. Sun, J. & Tower, J. (1999). FLP recombinase-mediated induction of Cu/ZnSOD transgene expression can extend the life span of adult Drosophila. Mol Cell Biol 19, 216-228.
45. Taub J., Lau J.F., Ma C., Hahn J.H., Hoque R., Rothblatt J., Chalfie M. A cytosolic catalase is needed to extend adult lifespan in C. elegans daf-C and clk-1 mutants. Nature. 399:1999;162-166.
46. Thompson J.N. Jr. Quantitative variation and gene number. Nature. 258:1975;665-668.
47. van Voorhies W.A., Ward S. Genetic and environmental conditions that increase longevity in Caenorhabditis elegans decrease metabolic rate. Proc Nat Acad Sci USA. 96:1999;11399-11403.
48. Vettraino, J. & Arking, R. (In preparation). Direct selection for paraquat resistance in Drosophila yields reciprocal effects on the P450 system and the antioxidant defense system.
49. Zar J.H. Biostatistical Analysis (2nd ed). 1974;Prentice-Hall, Englewood Cliffs, NJ.