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Volumn 169, Issue 2, 2003, Pages 115-134

Cannabinoids: Reward, dependence, and underlying neurochemical mechanisms - A review of recent preclinical data

Author keywords

Cannabinoid dependence; Conditioned place preference; Drug discrimination; Drug self administration; In vivo microdialysis; Marijuana; Opioid cannabinoid interactions; THC

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; ANANDAMIDE; BENZODIAZEPINE; CANNABINOID; CANNABINOID 1 RECEPTOR; CANNABINOID 1 RECEPTOR AGONIST; CANNABINOID RECEPTOR AGONIST; CANNABINOID RECEPTOR ANTAGONIST; COCAINE; DEXANABINOL; DIAMORPHINE; DIAZEPAM; DRONABINOL; METHANANDAMIDE; NALOXONE; NARCOTIC ANTAGONIST; RIMONABANT; UNCLASSIFIED DRUG;

EID: 0141451977     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-003-1485-z     Document Type: Review
Times cited : (234)

References (224)
  • 1
    • 0027368524 scopus 로고
    • Development of behavioral tolerance to delta 9-THC without alteration of cannabinoid receptor binding or mRNA levels in whole brain
    • Abood ME, Sauss C, Fan F, Tilton CL, Martin BR (1993) Development of behavioral tolerance to delta 9-THC without alteration of cannabinoid receptor binding or mRNA levels in whole brain. Pharmacol Biochem Behav 46:575-579
    • (1993) Pharmacol Biochem Behav , vol.46 , pp. 575-579
    • Abood, M.E.1    Sauss, C.2    Fan, F.3    Tilton, C.L.4    Martin, B.R.5
  • 2
    • 0029111498 scopus 로고
    • Cannabinoid precipitated withdrawal by the selective cannabinoid receptor antagonist, SR 141716A
    • Aceto MD, Scates SM, Lowe JA, Martin BR (1995) Cannabinoid precipitated withdrawal by the selective cannabinoid receptor antagonist, SR 141716A. Eur J Pharmacol 282:R1-R2
    • (1995) Eur J Pharmacol , vol.282
    • Aceto, M.D.1    Scates, S.M.2    Lowe, J.A.3    Martin, B.R.4
  • 3
    • 0030431226 scopus 로고    scopus 로고
    • Dependence on delta 9-tetrahydrocannabinol: Studies on precipitated and abrupt withdrawal
    • Aceto MD, Scares SM, Lowe JA, Martin BR (1996) Dependence on delta 9-tetrahydrocannabinol: studies on precipitated and abrupt withdrawal. J Pharmacol Exp Ther 278:1290-1295
    • (1996) J Pharmacol Exp Ther , vol.278 , pp. 1290-1295
    • Aceto, M.D.1    Scares, S.M.2    Lowe, J.A.3    Martin, B.R.4
  • 4
    • 0032468166 scopus 로고    scopus 로고
    • Anandamide, an endogenous cannabinoid, has a very low physical dependence potential
    • Aceto MD, Scares SM, Razdan RK, Martin BR (1998) Anandamide, an endogenous cannabinoid, has a very low physical dependence potential. J Pharmacol Exp Ther 287:598-605
    • (1998) J Pharmacol Exp Ther , vol.287 , pp. 598-605
    • Aceto, M.D.1    Scares, S.M.2    Razdan, R.K.3    Martin, B.R.4
  • 5
    • 0035937453 scopus 로고    scopus 로고
    • Spontaneous and precipitated withdrawal with a synthetic cannabinoid, WIN 55, 212-2
    • Aceto MD, Scares SM, Lowe JA, Martin BR (2001) Spontaneous and precipitated withdrawal with a synthetic cannabinoid, WIN 55,212-2. Eur J Pharmacol 416:75-81
    • (2001) Eur J Pharmacol , vol.416 , pp. 75-81
    • Aceto, M.D.1    Scares, S.M.2    Lowe, J.A.3    Martin, B.R.4
  • 6
    • 0026755615 scopus 로고
    • Depression of mesolimbic dopamine transmission and sensitization to morphine during opiate abstinence
    • Acquas E, Di Chiara G (1992) Depression of mesolimbic dopamine transmission and sensitization to morphine during opiate abstinence. J Neurochem 58:1620-1625
    • (1992) J Neurochem , vol.58 , pp. 1620-1625
    • Acquas, E.1    Di Chiara, G.2
  • 7
    • 0025976217 scopus 로고
    • Profound depression of mesolimbic dopamine release after morphine withdrawal in dependent rats
    • Acquas E, Carboni E, Di Chiara G (1991) Profound depression of mesolimbic dopamine release after morphine withdrawal in dependent rats. Eur J Pharmacol 193:133-134
    • (1991) Eur J Pharmacol , vol.193 , pp. 133-134
    • Acquas, E.1    Carboni, E.2    Di Chiara, G.3
  • 9
    • 0032926695 scopus 로고    scopus 로고
    • The effects of cannabinoids on the brain
    • Ameri A (1999) The effects of cannabinoids on the brain. Prog Neurobiol 58:315-348
    • (1999) Prog Neurobiol , vol.58 , pp. 315-348
    • Ameri, A.1
  • 10
    • 0031691194 scopus 로고    scopus 로고
    • Effects of pre-exposure and co-administration of the cannabinoid receptor agonist CP 55,940 on behavioral sensitization to cocaine
    • Arnold JC, Topple AN, Hunt GE, McGregor IS (1998) Effects of pre-exposure and co-administration of the cannabinoid receptor agonist CP 55, 940 on behavioral sensitization to cocaine. Eur J Pharmacol 354:9-16
    • (1998) Eur J Pharmacol , vol.354 , pp. 9-16
    • Arnold, J.C.1    Topple, A.N.2    Hunt, G.E.3    McGregor, I.S.4
  • 11
    • 0035205651 scopus 로고    scopus 로고
    • Effects of the cannabinoid receptor agonist CP 55,940 and the cannabinoid receptor antagonist SR 141716 on intracranial self-stimulation in Lewis rats
    • Arnold JC, Hunt GE, McGregor IS (2001) Effects of the cannabinoid receptor agonist CP 55,940 and the cannabinoid receptor antagonist SR 141716 on intracranial self-stimulation in Lewis rats. Life Sci 70:97-108
    • (2001) Life Sci , vol.70 , pp. 97-108
    • Arnold, J.C.1    Hunt, G.E.2    McGregor, I.S.3
  • 12
    • 0026516004 scopus 로고
    • Delta 9-tetrahydrocannabinol discrimination in rats as a model for cannabis intoxication
    • Balster RL, Prescott WR (1992) Delta 9-tetrahydrocannabinol discrimination in rats as a model for cannabis intoxication. Neurosci Biobehav Rev 16:55-62
    • (1992) Neurosci Biobehav Rev , vol.16 , pp. 55-62
    • Balster, R.L.1    Prescott, W.R.2
  • 13
    • 0015831552 scopus 로고
    • Fixed-interval schedule of cocaine reinforcement: Effect of dose and infusion duration
    • Balster RL, Schuster CR (1973) Fixed-interval schedule of cocaine reinforcement: effect of dose and infusion duration. J Exp Anal Behav 20:119-29
    • (1973) J Exp Anal Behav , vol.20 , pp. 119-129
    • Balster, R.L.1    Schuster, C.R.2
  • 14
    • 0034493070 scopus 로고    scopus 로고
    • Conditioned place preference: What does it add to our preclinical understanding of drug reward?
    • Bardo MT, Bevins RA (2000) Conditioned place preference: what does it add to our preclinical understanding of drug reward? Psychopharmacology 153:31-43
    • (2000) Psychopharmacology , vol.153 , pp. 31-43
    • Bardo, M.T.1    Bevins, R.A.2
  • 15
    • 0028958518 scopus 로고
    • Pharmacological specificity of Δ9-tetrahydrocannabinol discrimination in rats
    • Barrett RL, Wiley JL, Balster RL, Martin BR (1995) Pharmacological specificity of Δ9-tetrahydrocannabinol discrimination in rats. Psychopharmacology 118:419-424
    • (1995) Psychopharmacology , vol.118 , pp. 419-424
    • Barrett, R.L.1    Wiley, J.L.2    Balster, R.L.3    Martin, B.R.4
  • 16
    • 0034255129 scopus 로고    scopus 로고
    • Time course for the induction and maintenance of tolerance to delta-9-tetrahydrocannabinol in mice
    • Bass CE, Martin BR (2000) Time course for the induction and maintenance of tolerance to delta-9-tetrahydrocannabinol in mice. Drug Alcohol Depend 60:113-119
    • (2000) Drug Alcohol Depend , vol.60 , pp. 113-119
    • Bass, C.E.1    Martin, B.R.2
  • 17
    • 0021885896 scopus 로고
    • The reinforcing properties of diazepam under several conditions in the rhesus monkeys
    • Bergman J, Johnson GE (1985) The reinforcing properties of diazepam under several conditions in the rhesus monkeys. Psychopharmacology 86:108-113
    • (1985) Psychopharmacology , vol.86 , pp. 108-113
    • Bergman, J.1    Johnson, G.E.2
  • 18
    • 0035800002 scopus 로고    scopus 로고
    • Conditioned place preference induced by the cannabinoid agonist CP 55,940: Interaction with the opioid system
    • Braida D, Pozzi M, Cavallini R, Sala M (2001a) Conditioned place preference induced by the cannabinoid agonist CP 55,940: interaction with the opioid system. Neuroscience 104:923-926
    • (2001) Neuroscience , vol.104 , pp. 923-926
    • Braida, D.1    Pozzi, M.2    Cavallini, R.3    Sala, M.4
  • 19
    • 0035895535 scopus 로고    scopus 로고
    • Intracerebral self-administration of the cannabinoid receptor agonist CP 55,940 in the rat: Interaction with the opioid system
    • Braida D, Pozzi M, Parolaro D, Sala M (2001b) Intracerebral self-administration of the cannabinoid receptor agonist CP 55,940 in the rat: interaction with the opioid system. Eur J Pharmacol 413:227-234
    • (2001) Eur J Pharmacol , vol.413 , pp. 227-234
    • Braida, D.1    Pozzi, M.2    Parolaro, D.3    Sala, M.4
  • 20
    • 0032589999 scopus 로고    scopus 로고
    • Chronic delta9-tetrahydrocannabinol treatment produces a time-dependent loss of cannabinoid receptors and cannabinoid receptor-activated G proteins in rat brain
    • Breivogel CS, Childers SR, Deadwyler SA, Hampson RE, Vogt LJ, Sim-Selley LJ (1999) Chronic delta9-tetrahydrocannabinol treatment produces a time-dependent loss of cannabinoid receptors and cannabinoid receptor-activated G proteins in rat brain. J Neurochem 73:2447-2459
    • (1999) J Neurochem , vol.73 , pp. 2447-2459
    • Breivogel, C.S.1    Childers, S.R.2    Deadwyler, S.A.3    Hampson, R.E.4    Vogt, L.J.5    Sim-Selley, L.J.6
  • 21
    • 0034948614 scopus 로고    scopus 로고
    • Evidence for a new G protein-coupled cannabinoid receptor in mouse brain
    • Breivogel CS, Griffin G, Di Marzo V, Martin BR (2001) Evidence for a new G protein-coupled cannabinoid receptor in mouse brain. Mol Pharmacol 60:155-163
    • (2001) Mol Pharmacol , vol.60 , pp. 155-163
    • Breivogel, C.S.1    Griffin, G.2    Di Marzo, V.3    Martin, B.R.4
  • 22
    • 0032862820 scopus 로고    scopus 로고
    • Marijuana withdrawal among adults seeking treatment for marijuana dependence
    • Budney AJ, Novy PL, Hughes JR (1999) Marijuana withdrawal among adults seeking treatment for marijuana dependence. Addiction 94:1311-1322
    • (1999) Addiction , vol.94 , pp. 1311-1322
    • Budney, A.J.1    Novy, P.L.2    Hughes, J.R.3
  • 23
    • 0034792214 scopus 로고    scopus 로고
    • Marijuana abstinence effects in marijuana smokers maintained in their home environment
    • Budney, AJ, Hughes JR, Moore BA, Novy PL (2001) Marijuana abstinence effects in marijuana smokers maintained in their home environment. Arch Gen Psychiatry 58:917-924
    • (2001) Arch Gen Psychiatry , vol.58 , pp. 917-924
    • Budney, A.J.1    Hughes, J.R.2    Moore, B.A.3    Novy, P.L.4
  • 24
    • 0030744309 scopus 로고    scopus 로고
    • (R)-Methanandamide, but not anandamide, substitutes for Δ9-THC in a drug-discrimination procedure
    • Burkey RT, Nation JR (1997) (R)-Methanandamide, but not anandamide, substitutes for Δ9-THC in a drug-discrimination procedure. Exp Clin Psychopharmacol 5:195-202
    • (1997) Exp Clin Psychopharmacol , vol.5 , pp. 195-202
    • Burkey, R.T.1    Nation, J.R.2
  • 26
    • 0035843772 scopus 로고    scopus 로고
    • Antinociceptive activity of the endogenous fatty acid amide, palmitylethanolamide
    • Calignano A, La Rana G, Piomelli D (2001) Antinociceptive activity of the endogenous fatty acid amide, palmitylethanolamide. Eur J Pharmacol 419:191-198
    • (2001) Eur J Pharmacol , vol.419 , pp. 191-198
    • Calignano, A.1    La Rana, G.2    Piomelli, D.3
  • 27
    • 0033735407 scopus 로고    scopus 로고
    • Acquisition of drug self-administration: Environmental and pharmacological interventions
    • Campbell UC, Carroll ME (2000) Acquisition of drug self-administration: environmental and pharmacological interventions. Exp Clin Psychopharmacol 8:312-325
    • (2000) Exp Clin Psychopharmacol , vol.8 , pp. 312-325
    • Campbell, U.C.1    Carroll, M.E.2
  • 28
    • 0024513346 scopus 로고
    • Amphetamine, cocaine, phencyclidine and nomifensine increase extracellular dopamine concentrations preferentially in the nucleus accumbens of freely moving rats
    • Carboni E, Imperato A, Perezzani L, Di Chiara G (1989) Amphetamine, cocaine, phencyclidine and nomifensine increase extracellular dopamine concentrations preferentially in the nucleus accumbens of freely moving rats. Neuroscience 28:653-661
    • (1989) Neuroscience , vol.28 , pp. 653-661
    • Carboni, E.1    Imperato, A.2    Perezzani, L.3    Di Chiara, G.4
  • 29
    • 0017663698 scopus 로고
    • Evaluation of a suspension system for intravenous self-administration of water insoluble substances in the rhesus monkey
    • Carney JM, Uwaydah IM, Balster, RL (1977) Evaluation of a suspension system for intravenous self-administration of water insoluble substances in the rhesus monkey. Pharmacol Biochem Behav 7:357-364
    • (1977) Pharmacol Biochem Behav , vol.7 , pp. 357-364
    • Carney, J.M.1    Uwaydah, I.M.2    Balster, R.L.3
  • 30
    • 0036062518 scopus 로고    scopus 로고
    • Augmentation of drug reward by chronic food restriction: Behavioral evidence and underlying mechanisms
    • Carr KD (2002) Augmentation of drug reward by chronic food restriction: behavioral evidence and underlying mechanisms. Physiol Behav 76:353-364
    • (2002) Physiol Behav , vol.76 , pp. 353-364
    • Carr, K.D.1
  • 31
    • 0031969546 scopus 로고    scopus 로고
    • A detailed characterization of the effects of four cannabinoid agonists on operant lever pressing
    • Carriero D, Aberman J, Lin SY, Hill A, Makriyannis A, Salamone JD (1998) A detailed characterization of the effects of four cannabinoid agonists on operant lever pressing. Psychopharmacology 137:147-156
    • (1998) Psychopharmacology , vol.137 , pp. 147-156
    • Carriero, D.1    Aberman, J.2    Lin, S.Y.3    Hill, A.4    Makriyannis, A.5    Salamone, J.D.6
  • 32
    • 0025720573 scopus 로고
    • THC does not affect striatal dopamine release: Microdialysis in freely moving rats
    • Castaneda E, Moss DE, Oddie SD, Whishaw IQ (1991) THC does not affect striatal dopamine release: microdialysis in freely moving rats. Pharmacol Biochem Behav 40:587-591
    • (1991) Pharmacol Biochem Behav , vol.40 , pp. 587-591
    • Castaneda, E.1    Moss, D.E.2    Oddie, S.D.3    Whishaw, I.Q.4
  • 33
    • 0028295263 scopus 로고
    • Electrophysiological and pharmacological evidence for the role of the nucleus accumbens in cocaine self-administration in freely moving rats
    • Chang JY, Sawyer SF, Lee RS, Woodward DJ (1994) Electrophysiological and pharmacological evidence for the role of the nucleus accumbens in cocaine self-administration in freely moving rats. J Neurosci 14:1224-1244
    • (1994) J Neurosci , vol.14 , pp. 1224-1244
    • Chang, J.Y.1    Sawyer, S.F.2    Lee, R.S.3    Woodward, D.J.4
  • 34
    • 0031780582 scopus 로고    scopus 로고
    • Involvement of central cannabinoid (CB1) receptors in the establishment of place conditioning in rats
    • Chaperon F, Soubrie P, Puech AJ, Thiebot MH (1998) Involvement of central cannabinoid (CB1) receptors in the establishment of place conditioning in rats. Psychopharmacology 135:324-332
    • (1998) Psychopharmacology , vol.135 , pp. 324-332
    • Chaperon, F.1    Soubrie, P.2    Puech, A.J.3    Thiebot, M.H.4
  • 35
    • 0033873630 scopus 로고    scopus 로고
    • Cannabinoid receptors and reward in the rat: A conditioned place preference study
    • Cheer JF, Kendall DA, Marsden CA (2000a) Cannabinoid receptors and reward in the rat: a conditioned place preference study. Psychopharmacology 151:25-30
    • (2000) Psychopharmacology , vol.151 , pp. 25-30
    • Cheer, J.F.1    Kendall, D.A.2    Marsden, C.A.3
  • 36
    • 0034706069 scopus 로고    scopus 로고
    • Lack of response suppression follows repeated ventral tegmental cannabinoid administration: An in vitro electrophysiological study
    • Cheer JF, Marsden CA, Kendall DA, Mason R (2000b) Lack of response suppression follows repeated ventral tegmental cannabinoid administration: an in vitro electrophysiological study. Neuroscience 99:661-667
    • (2000) Neuroscience , vol.99 , pp. 661-667
    • Cheer, J.F.1    Marsden, C.A.2    Kendall, D.A.3    Mason, R.4
  • 37
    • 0025161255 scopus 로고
    • Δ9-Tetrahydrocannabinol produces naloxoneblockable enhancement of presynaptic basal dopamine efflux in nucleus accumbens of conscious, freely-moving rats as measured by intracerebral microdialysis
    • Chen J, Paredes W, Li J, Smith D, Lowinson JH, Gardner EL (1990) Δ9-Tetrahydrocannabinol produces naloxoneblockable enhancement of presynaptic basal dopamine efflux in nucleus accumbens of conscious, freely-moving rats as measured by intracerebral microdialysis. Psychopharmacology 102:156-162
    • (1990) Psychopharmacology , vol.102 , pp. 156-162
    • Chen, J.1    Paredes, W.2    Li, J.3    Smith, D.4    Lowinson, J.H.5    Gardner, E.L.6
  • 38
    • 0025861342 scopus 로고
    • Strain-specific facilitation of dopamine efflux by Δ 9-tetrahydrocannabinol in the nucleus accumbens of rat: An in vivo microdialysis study
    • Chen J, Paredes W, Lowinson JH, Gardner EL (1991) Strain-specific facilitation of dopamine efflux by Δ9-tetrahydrocannabinol in the nucleus accumbens of rat: an in vivo microdialysis study. Neurosci Lett 129:136-140
    • (1991) Neurosci Lett , vol.129 , pp. 136-140
    • Chen, J.1    Paredes, W.2    Lowinson, J.H.3    Gardner, E.L.4
  • 39
    • 0027328893 scopus 로고
    • Ventral tegmental microinjection of delta 9-tetrahydrocannabinol enhances ventral tegmental somatodendritic dopamine levels but not forebrain dopamine levels: Evidence for local neural action by marijuana's psychoactive ingredient
    • Chen J, Marmur R, Pulles A, Paredes W, Gardner EL (1993) Ventral tegmental microinjection of delta 9-tetrahydrocannabinol enhances ventral tegmental somatodendritic dopamine levels but not forebrain dopamine levels: evidence for local neural action by marijuana's psychoactive ingredient. Brain Res 621:65-70
    • (1993) Brain Res , vol.621 , pp. 65-70
    • Chen, J.1    Marmur, R.2    Pulles, A.3    Paredes, W.4    Gardner, E.L.5
  • 40
  • 41
    • 0030901502 scopus 로고    scopus 로고
    • Delta 9-Tetrahydrocannabinol increases proopiomelanocortin gene expression in the arcuate nucleus of the rat hypothalamus
    • Corchero J, Fuentes JA, Manzanares J (1997a) Delta 9-Tetrahydrocannabinol increases proopiomelanocortin gene expression in the arcuate nucleus of the rat hypothalamus. Eur J Pharmacol 323:193-195
    • (1997) Eur J Pharmacol , vol.323 , pp. 193-195
    • Corchero, J.1    Fuentes, J.A.2    Manzanares, J.3
  • 42
    • 0030871674 scopus 로고    scopus 로고
    • Δ9-tetrahydrocannabinol increases prodynorphin and proenkephalin gene expression in the spinal cord of the rat
    • Corchero J, Avila MA, Fuentes JA, Manzanares J (1997b) Δ9-tetrahydrocannabinol increases prodynorphin and proenkephalin gene expression in the spinal cord of the rat. Life Sci 61:39-43
    • (1997) Life Sci , vol.61 , pp. 39-43
    • Corchero, J.1    Avila, M.A.2    Fuentes, J.A.3    Manzanares, J.4
  • 43
    • 0030579091 scopus 로고    scopus 로고
    • Chronic cannabinoid, CP-55,940, administration alters biotransformation in the rat
    • Costa B, Parolaro D, Colleoni M (1996) Chronic cannabinoid, CP-55,940, administration alters biotransformation in the rat. Eur J Pharmacol 313:17-24
    • (1996) Eur J Pharmacol , vol.313 , pp. 17-24
    • Costa, B.1    Parolaro, D.2    Colleoni, M.3
  • 44
    • 0034050911 scopus 로고    scopus 로고
    • Precipitated and spontaneous withdrawal in rats tolerant to anandamide
    • Costa B, Giagnoni G, Colleoni M (2000) Precipitated and spontaneous withdrawal in rats tolerant to anandamide. Psychopharmacology 149:121-128
    • (2000) Psychopharmacology , vol.149 , pp. 121-128
    • Costa, B.1    Giagnoni, G.2    Colleoni, M.3
  • 48
    • 0032033044 scopus 로고    scopus 로고
    • Cannabis dependence, withdrawal, and reinforcing effects among adolescents with conduct symptoms and substance use disorders
    • Crowley TJ, Macdonald MJ, Whitmore EA, Mikulich SK (1998) Cannabis dependence, withdrawal, and reinforcing effects among adolescents with conduct symptoms and substance use disorders. Drug Alcohol Depend 50:27-37
    • (1998) Drug Alcohol Depend , vol.50 , pp. 27-37
    • Crowley, T.J.1    Macdonald, M.J.2    Whitmore, E.A.3    Mikulich, S.K.4
  • 49
    • 0024454303 scopus 로고
    • Lack of tolerance to nicotine-induced dopamine release in the nucleus accumbens
    • Damsma G, Day J, Fibiger HC (1989) Lack of tolerance to nicotine-induced dopamine release in the nucleus accumbens. Eur J Pharmacol 168:363-368
    • (1989) Eur J Pharmacol , vol.168 , pp. 363-368
    • Damsma, G.1    Day, J.2    Fibiger, H.C.3
  • 50
    • 0035900589 scopus 로고    scopus 로고
    • Rapid tolerance to Delta(9)-tetrahydrocannabinol and cross-tolerance between ethanol and Delta(9)-tetrahydrocannabinol in mice
    • Da Silva GE, Morato GS, Takahashi RN (2001) Rapid tolerance to Delta(9)-tetrahydrocannabinol and cross-tolerance between ethanol and Delta(9)-tetrahydrocannabinol in mice. Eur J Pharmacol 431:201-207
    • (2001) Eur J Pharmacol , vol.431 , pp. 201-207
    • Da Silva, G.E.1    Morato, G.S.2    Takahashi, R.N.3
  • 53
    • 0039534405 scopus 로고    scopus 로고
    • Activation of corticotropin-releasing factor in the limbic system during cannabinoid withdrawal
    • De Fonseca RF, Carrera MRA, Navarro M, Koob GF, Weiss F (1997) Activation of corticotropin-releasing factor in the limbic system during cannabinoid withdrawal. Science 276:2050-2054
    • (1997) Science , vol.276 , pp. 2050-2054
    • De Fonseca, R.F.1    Carrera, M.R.A.2    Navarro, M.3    Koob, G.F.4    Weiss, F.5
  • 56
    • 0032457863 scopus 로고    scopus 로고
    • Drug-induced reinstatement of heroin- and cocaine-seeking behaviour following long-term extinction is associated with expression of behavioural sensitization
    • De Vries TJ, Schoffelmeer AN, Binnekade R, Mulder AH, Vanderschuren LJ (1998) Drug-induced reinstatement of heroin- and cocaine-seeking behaviour following long-term extinction is associated with expression of behavioural sensitization. Eur J Neurosci 10:3565-3571
    • (1998) Eur J Neurosci , vol.10 , pp. 3565-3571
    • De Vries, T.J.1    Schoffelmeer, A.N.2    Binnekade, R.3    Mulder, A.H.4    Vanderschuren, L.J.5
  • 57
  • 58
    • 0022930728 scopus 로고
    • Preferential stimulation of dopamine release in the nucleus accumbens by opiates, alcohol, and barbiturates: Studies with transcerebral dialysis in freely moving rats
    • Di Chiara G, Imperato A (1986) Preferential stimulation of dopamine release in the nucleus accumbens by opiates, alcohol, and barbiturates: studies with transcerebral dialysis in freely moving rats. Ann NY Acad Sci 473:367-381
    • (1986) Ann NY Acad Sci , vol.473 , pp. 367-381
    • Di Chiara, G.1    Imperato, A.2
  • 59
    • 0343933624 scopus 로고
    • Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats
    • Di Chiara G, Imperato A (1988) Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc Natl Acad Sci USA 85:5274-5278
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 5274-5278
    • Di Chiara, G.1    Imperato, A.2
  • 61
    • 0032814694 scopus 로고    scopus 로고
    • Drug addiction as a disorder of associative learning: ROle of nucleus accumbens shell/extended amygdala dopamine
    • Di Chiara G, Tanda G, Bassamo V, Pontieri F, Acquas E, Fenu S, Cadoni C, Carboni E (1999) Drug addiction as a disorder of associative learning: role of nucleus accumbens shell/extended amygdala dopamine. Ann NY Acad Sci 877:461-485
    • (1999) Ann NY Acad Sci , vol.877 , pp. 461-485
    • Di Chiara, G.1    Tanda, G.2    Bassamo, V.3    Pontieri, F.4    Acquas, E.5    Fenu, S.6    Cadoni, C.7    Carboni, E.8
  • 62
    • 0033538537 scopus 로고    scopus 로고
    • Biosynthesis and inactivation of endocannabinoids: Relevance to their proposed role as neuromodulators
    • Di Marzo V (1999) Biosynthesis and inactivation of endocannabinoids: relevance to their proposed role as neuromodulators. Life Sci 65:645-655
    • (1999) Life Sci , vol.65 , pp. 645-655
    • Di Marzo, V.1
  • 64
    • 0034107992 scopus 로고    scopus 로고
    • Enhancement of anandamide formation in the limbic forebrain and reduction of endocannabinoid contents in the striatum of delta9-tetrahydrocannabinol-tolerant rats
    • Di Marzo V, Berrendero F, Bisogno T, Gonzalez S, Cavaliere P, Romero J, Cebeira M, Ramos JA, Fernandez-Ruiz JJ (2000) Enhancement of anandamide formation in the limbic forebrain and reduction of endocannabinoid contents in the striatum of delta9-tetrahydrocannabinol-tolerant rats. J Neurochem 74:1627-1635
    • (2000) J Neurochem , vol.74 , pp. 1627-1635
    • Di Marzo, V.1    Berrendero, F.2    Bisogno, T.3    Gonzalez, S.4    Cavaliere, P.5    Romero, J.6    Cebeira, M.7    Ramos, J.A.8    Fernandez-Ruiz, J.J.9
  • 65
    • 0028277373 scopus 로고
    • Discriminative stimulus effects of phencyclidine: Pharmacologically specific interactions with delta 9- and delta 8-tetrahydrocannabinol
    • Doty P, Dykstra LA, Picker MJ (1994) Discriminative stimulus effects of phencyclidine: pharmacologically specific interactions with delta 9- and delta 8-tetrahydrocannabinol. Drug Alcohol Depend 35:151-158
    • (1994) Drug Alcohol Depend , vol.35 , pp. 151-158
    • Doty, P.1    Dykstra, L.A.2    Picker, M.J.3
  • 66
    • 0034941981 scopus 로고    scopus 로고
    • Intravenous self-administration of the cannabinoid CB1 receptor agonist WIN 55,212-2 in rats
    • Fattore L, Cossu G, Martellotta CM, Fratta W (2001) Intravenous self-administration of the cannabinoid CB1 receptor agonist WIN 55,212-2 in rats. Psychopharmacology 156:410-416
    • (2001) Psychopharmacology , vol.156 , pp. 410-416
    • Fattore, L.1    Cossu, G.2    Martellotta, C.M.3    Fratta, W.4
  • 67
    • 0031749186 scopus 로고    scopus 로고
    • Cannabinoid receptors and their endogenous agonists
    • Felder CC, Glass M (1998) Cannabinoid receptors and their endogenous agonists. Annu Rev Pharmacol Toxicol 3:179-200
    • (1998) Annu Rev Pharmacol Toxicol , vol.3 , pp. 179-200
    • Felder, C.C.1    Glass, M.2
  • 68
    • 0030887785 scopus 로고    scopus 로고
    • Cannabinoids excite dopamine neurons in the ventral tegmentum and substantia nigra
    • French ED, Dillon K, Wu X (1997) Cannabinoids excite dopamine neurons in the ventral tegmentum and substantia nigra. Neuroreport 8:649-652
    • (1997) Neuroreport , vol.8 , pp. 649-652
    • French, E.D.1    Dillon, K.2    Wu, X.3
  • 69
    • 33947489961 scopus 로고
    • Isolation, structure, and partial synthesis of an active constituent of hashish
    • Gaoni Y, Mechoulam R (1964) Isolation, structure, and partial synthesis of an active constituent of hashish. J Am Chem Soc 86:1646-1647
    • (1964) J Am Chem Soc , vol.86 , pp. 1646-1647
    • Gaoni, Y.1    Mechoulam, R.2
  • 70
    • 0000573446 scopus 로고
    • Facilitation of brain stimulation reward by delta-9-tetrahydrocannabinol is mediated by an endogenous opioid mechanism
    • Gardner EL, Parades W, Smith D, Zukin RS (1989) facilitation of brain stimulation reward by delta-9-tetrahydrocannabinol is mediated by an endogenous opioid mechanism. Adv Biosci 75:671-674
    • (1989) Adv Biosci , vol.75 , pp. 671-674
    • Gardner, E.L.1    Parades, W.2    Smith, D.3    Zukin, R.S.4
  • 71
    • 0032461050 scopus 로고    scopus 로고
    • Cannabinoid transmission and reward related events
    • Gardner EL, Vorel SR (1998) Cannabinoid transmission and reward related events. Neurobiol Dis 5:502-533
    • (1998) Neurobiol Dis , vol.5 , pp. 502-533
    • Gardner, E.L.1    Vorel, S.R.2
  • 73
    • 0030791135 scopus 로고    scopus 로고
    • The effect of intravenous administration of delta-9-tetrahydrocannabinol on the activity of A10 dopamine neurons recorded in vivo in anesthetized rats
    • Gifford AN, Gardner EL, Ashby CR Jr (1997) The effect of intravenous administration of delta-9-tetrahydrocannabinol on the activity of A10 dopamine neurons recorded in vivo in anesthetized rats. Neuropsychobiology 36:96-99
    • (1997) Neuropsychobiology , vol.36 , pp. 96-99
    • Gifford, A.N.1    Gardner, E.L.2    Ashby C.R., Jr.3
  • 74
    • 0033592583 scopus 로고    scopus 로고
    • Potentiation of the action of anandamide on hippocampal slices by the fatty acid amide hydrolase inhibitor, palmitylsulphonyl fluoride (AM 374)
    • Gifford AN, Bruneus M, Lin S, Goutopoulos A, Makriyannis A, Volkow ND, Gatley SJ (1999) Potentiation of the action of anandamide on hippocampal slices by the fatty acid amide hydrolase inhibitor, palmitylsulphonyl fluoride (AM 374). Eur J Pharmacol 383:9-14
    • (1999) Eur J Pharmacol , vol.383 , pp. 9-14
    • Gifford, A.N.1    Bruneus, M.2    Lin, S.3    Goutopoulos, A.4    Makriyannis, A.5    Volkow, N.D.6    Gatley, S.J.7
  • 75
    • 0034978249 scopus 로고    scopus 로고
    • Mechanisms of endocannabinoid inactivation: Biochemistry and pharmacology
    • Giuffrida A, Beltramo M, Piomelli D (2001) Mechanisms of endocannabinoid inactivation: biochemistry and pharmacology. J Pharmacol Exp Ther 298:7-14
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 7-14
    • Giuffrida, A.1    Beltramo, M.2    Piomelli, D.3
  • 76
    • 0026726365 scopus 로고
    • Comparison of the discriminative stimulus properties of delta 9-tetrahydrocannabinol and CP 55,940 in rats and rhesus monkeys
    • Gold LH, Balster RL, Barrett RL, Britt DT, Martin BRA (1992) Comparison of the discriminative stimulus properties of delta 9-tetrahydrocannabinol and CP 55,940 in rats and rhesus monkeys. J Pharmacol Exp Ther 262:479-486
    • (1992) J Pharmacol Exp Ther , vol.262 , pp. 479-486
    • Gold, L.H.1    Balster, R.L.2    Barrett, R.L.3    Britt, D.T.4    Martin, B.R.A.5
  • 77
    • 0002096761 scopus 로고    scopus 로고
    • Effect of naltrexone on intravenous self-administration of delta-9-tetrahydrocannabinol (THC) by squirrel monkeys under fixed-ratio and second-order schedules
    • International Cannabinoid Research Society, Burlington
    • Goldberg SR, Munzar P, Justinova Z, Tanda G (2001) Effect of naltrexone on intravenous self-administration of delta-9-tetrahydrocannabinol (THC) by squirrel monkeys under fixed-ratio and second-order schedules. In: Abstracts of the 2001 symposium on cannabinoids. International Cannabinoid Research Society, Burlington, p 102
    • (2001) Abstracts of the 2001 Symposium on Cannabinoids , pp. 102
    • Goldberg, S.R.1    Munzar, P.2    Justinova, Z.3    Tanda, G.4
  • 78
    • 0032587994 scopus 로고    scopus 로고
    • Chronic (-)-delta9-tetrahydrocannabinol treatment induces sensitization to the psychomotor effects of amphetamine in rats
    • Gorriti MA, Rodriguez de Fonseca F, Navarro M, Palomo T (1999) Chronic (-)-delta9-tetrahydrocannabinol treatment induces sensitization to the psychomotor effects of amphetamine in rats. Eur J Pharmacol 365:133-142
    • (1999) Eur J Pharmacol , vol.365 , pp. 133-142
    • Gorriti, M.A.1    Rodriguez De Fonseca, F.2    Navarro, M.3    Palomo, T.4
  • 79
    • 0034212169 scopus 로고    scopus 로고
    • Antinociceptive, subjective and behavioral effects of smoked marijuana in humans
    • Greenwald MK, Stitzer ML (2000) Antinociceptive, subjective and behavioral effects of smoked marijuana in humans. Drug Alcohol Depend 59:261-275
    • (2000) Drug Alcohol Depend , vol.59 , pp. 261-275
    • Greenwald, M.K.1    Stitzer, M.L.2
  • 80
    • 0141442379 scopus 로고
    • Similarities in reinforcing and discriminative stimulus effects of diazepam, triazolam, and pentobarbital in animals and humans
    • Seiden LS, Balster RL (eds). Liss, New York
    • Griffiths RR, Roache JD, Ator NA, Lamb RJ, Lukas SE (1985) Similarities in reinforcing and discriminative stimulus effects of diazepam, triazolam, and pentobarbital in animals and humans. In: Seiden LS, Balster RL (eds) Behavioral pharmacology: the current status. Liss, New York, pp 419-432
    • (1985) Behavioral Pharmacology: The Current Status , pp. 419-432
    • Griffiths, R.R.1    Roache, J.D.2    Ator, N.A.3    Lamb, R.J.4    Lukas, S.E.5
  • 84
    • 0016168395 scopus 로고
    • Evaluation of reinforcing capability of Δ9-tetrahydrocannabinol in monkeys
    • Harris RT, Waters W, McLendon D (1974) Evaluation of reinforcing capability of Δ9-tetrahydrocannabinol in monkeys. Psychopharmacologia 37:23-29
    • (1974) Psychopharmacologia , vol.37 , pp. 23-29
    • Harris, R.T.1    Waters, W.2    McLendon, D.3
  • 85
    • 0023946717 scopus 로고
    • Food reward and cocaine increase extracellular dopamine in the nucleus accumbens as measured by microdialysis
    • Hernandez L, Hoebel BG (1988) Food reward and cocaine increase extracellular dopamine in the nucleus accumbens as measured by microdialysis. Life Sci 42:1705-1712
    • (1988) Life Sci , vol.42 , pp. 1705-1712
    • Hernandez, L.1    Hoebel, B.G.2
  • 86
    • 0033666960 scopus 로고    scopus 로고
    • The movement of N-arachidonoylethanolamine (anandamide) across cellular membranes
    • Hillard CJ, Jarrahian A (2000) The movement of N-arachidonoylethanolamine (anandamide) across cellular membranes. Chem Phys Lipids 108:123-134
    • (2000) Chem Phys Lipids , vol.108 , pp. 123-134
    • Hillard, C.J.1    Jarrahian, A.2
  • 87
    • 0016427104 scopus 로고
    • Morphine-dependent rats: Blockade of precipitated abstinence by tetrahydrocannabinol
    • Hine B, Friedman E, Torrelio M, Gershon S (1975) Morphine-dependent rats: blockade of precipitated abstinence by tetrahydrocannabinol. Science 187:443-445
    • (1975) Science , vol.187 , pp. 443-445
    • Hine, B.1    Friedman, E.2    Torrelio, M.3    Gershon, S.4
  • 89
    • 0031793070 scopus 로고    scopus 로고
    • Behavioral and biochemical evidence for signs of abstinence in mice chronically treated with delta-9-tetrahydrocannabinol
    • Hutcheson DM, Tzavara ET Smadja C, Valjent E, Roques BP, Hanoune J, Maldonado R (1998) Behavioral and biochemical evidence for signs of abstinence in mice chronically treated with delta-9-tetrahydrocannabinol. Br J Pharmacol 125:1567-1577
    • (1998) Br J Pharmacol , vol.125 , pp. 1567-1577
    • Hutcheson, D.M.1    Tzavara, E.T.2    Smadja, C.3    Valjent, E.4    Roques, B.P.5    Hanoune, J.6    Maldonado, R.7
  • 91
    • 0031593713 scopus 로고    scopus 로고
    • Δ9-THC training dose as a determinant for (R)-methanandamide generalization in rats
    • Järbe TU, Lamb RJ, Makriyannis A, Lin S, Goutopoulos A (1998) Δ9-THC training dose as a determinant for (R)-methanandamide generalization in rats. Psychopharmacology 140:519-522
    • (1998) Psychopharmacology , vol.140 , pp. 519-522
    • Järbe, T.U.1    Lamb, R.J.2    Makriyannis, A.3    Lin, S.4    Goutopoulos, A.5
  • 92
    • 0033625524 scopus 로고    scopus 로고
    • Delta 9-THC training dose as a determinant for (R)-methanandamide generalization in rats: A systematic replication
    • Järbe TU, Lamb RJ, Lin S, Makriyannis A (2000) Delta 9-THC training dose as a determinant for (R)-methanandamide generalization in rats: a systematic replication. Behav Pharmacol 11:81-86
    • (2000) Behav Pharmacol , vol.11 , pp. 81-86
    • Järbe, T.U.1    Lamb, R.J.2    Lin, S.3    Makriyannis, A.4
  • 93
    • 0034939394 scopus 로고    scopus 로고
    • (R)-methanandamide and Delta 9-THC as discriminative stimuli in rats: Tests with the cannabinoid antagonist SR-141716 and the endogenous ligand anandamide
    • Järbe TU, Lamb RJ, Lin S, Makriyannis A (2001) (R)-methanandamide and Delta 9-THC as discriminative stimuli in rats: tests with the cannabinoid antagonist SR-141716 and the endogenous ligand anandamide. Psychopharmacology 156:369-380
    • (2001) Psychopharmacology , vol.156 , pp. 369-380
    • Järbe, T.U.1    Lamb, R.J.2    Lin, S.3    Makriyannis, A.4
  • 94
    • 0026592638 scopus 로고
    • Opioids excite dopamine neurons by hyperpolarization of local interneurons
    • Johnson SW, North RA (1992) Opioids excite dopamine neurons by hyperpolarization of local interneurons. J Neurosci 12:483-488
    • (1992) J Neurosci , vol.12 , pp. 483-488
    • Johnson, S.W.1    North, R.A.2
  • 95
    • 0141451976 scopus 로고    scopus 로고
    • Self-administration of Δ9-tetrahydrocannabinol (THC) by drug naive squirrel monkeys
    • DOI 10.1007/s00213-003-1484-0
    • Justinova Z, Tanda G, Redhi GH, Goldberg SR (2003) Self-administration of Δ9-tetrahydrocannabinol (THC) by drug naive squirrel monkeys. Psychopharmacology DOI 10.1007/s00213-003-1484-0
    • (2003) Psychopharmacology
    • Justinova, Z.1    Tanda, G.2    Redhi, G.H.3    Goldberg, S.R.4
  • 96
    • 0025272661 scopus 로고
    • Effect of acute and daily cocaine treatment on extracellular dopamine in the nucleus accumbens
    • Kalivas PW, Duffy P (1990) Effect of acute and daily cocaine treatment on extracellular dopamine in the nucleus accumbens. Synapse 5:48-58
    • (1990) Synapse , vol.5 , pp. 48-58
    • Kalivas, P.W.1    Duffy, P.2
  • 97
    • 0023520858 scopus 로고
    • Relationship between minimum reinforcing doses and injection speed in cocaine and pentobarbital self-administration in crab-eating monkeys
    • Kato S, Wakasa Y, Yanagita T (1987) Relationship between minimum reinforcing doses and injection speed in cocaine and pentobarbital self-administration in crab-eating monkeys. Pharmacol Biochem Behav 28:407-10
    • (1987) Pharmacol Biochem Behav , vol.28 , pp. 407-410
    • Kato, S.1    Wakasa, Y.2    Yanagita, T.3
  • 99
    • 0023878295 scopus 로고
    • Preclinical assessment of abuse liability of drugs
    • Katz JL, Goldberg SR (1988) Preclinical assessment of abuse liability of drugs. Agents Actions 23:18-26
    • (1988) Agents Actions , vol.23 , pp. 18-26
    • Katz, J.L.1    Goldberg, S.R.2
  • 100
    • 0003057215 scopus 로고
    • Physiology and psychological dependence on THC in rhesus monkeys
    • Paton WDM, Crown J (eds). Oxford University Press, London
    • Kaymakcalan S (1972) Physiology and psychological dependence on THC in rhesus monkeys. In: Paton WDM, Crown J (eds) Cannabis and its derivatives. Oxford University Press, London, pp 142-149
    • (1972) Cannabis and its Derivatives , pp. 142-149
    • Kaymakcalan, S.1
  • 101
    • 0015738789 scopus 로고
    • Tolerance to and dependence on cannabis
    • Kaymakcalan S (1973) Tolerance to and dependence on cannabis. Bull Narc 25:39-47
    • (1973) Bull Narc , vol.25 , pp. 39-47
    • Kaymakcalan, S.1
  • 102
    • 0017689682 scopus 로고
    • Naloxone-induced or postwithdrawal abstinence signs in delta9-tetrahydrocannabinol-tolerant rats
    • Kaymakcalan S, Ayhan IH, Tulunay FC (1977) Naloxone-induced or postwithdrawal abstinence signs in delta9-tetrahydrocannabinol-tolerant rats. Psychopharmacology 55:243-249
    • (1977) Psychopharmacology , vol.55 , pp. 243-249
    • Kaymakcalan, S.1    Ayhan, I.H.2    Tulunay, F.C.3
  • 103
    • 0032586698 scopus 로고    scopus 로고
    • Responses to oral delta9-tetrahydrocannabinol in frequent and infrequent marijuana users
    • Kirk JM, De Wit H (1999) Responses to oral delta9-tetrahydrocannabinol in frequent and infrequent marijuana users. Pharmacol Biochem Behav 63:137-142
    • (1999) Pharmacol Biochem Behav , vol.63 , pp. 137-142
    • Kirk, J.M.1    De Wit, H.2
  • 104
    • 0026507628 scopus 로고
    • Drugs of abuse: Anatomy, pharmacology and function of reward pathways
    • Koob GF (1992) Drugs of abuse: anatomy, pharmacology and function of reward pathways. Trends Pharmacol Sci 13:177-184
    • (1992) Trends Pharmacol Sci , vol.13 , pp. 177-184
    • Koob, G.F.1
  • 105
    • 0030756351 scopus 로고    scopus 로고
    • Drug abuse: Hedonic homeostatic dysregulation
    • Koob GF, Le Moal M (1997) Drug abuse: hedonic homeostatic dysregulation. Science 278:52-58
    • (1997) Science , vol.278 , pp. 52-58
    • Koob, G.F.1    Le Moal, M.2
  • 106
    • 0035199891 scopus 로고    scopus 로고
    • Drug addiction, dysregulation of reward and allostasis
    • Koob GF, Le Moal M (2001) Drug addiction, dysregulation of reward and allostasis. Neuropsychopharmocology 24:97-129
    • (2001) Neuropsychopharmocology , vol.24 , pp. 97-129
    • Koob, G.F.1    Le Moal, M.2
  • 107
    • 0032104659 scopus 로고    scopus 로고
    • Drug dependence: Stress and dysregulation of brain reward pathways
    • Kreek MJ, Koob GF (1998) Drug dependence: stress and dysregulation of brain reward pathways. Drug Alcohol Depend 51:23-47
    • (1998) Drug Alcohol Depend , vol.51 , pp. 23-47
    • Kreek, M.J.1    Koob, G.F.2
  • 108
    • 0025790368 scopus 로고
    • Amphetamine, cocaine, and fencamfamine: Relationship between locomotor and stereotypy response profiles and caudate and accumbens dopamine dynamics
    • Kuczenski R, Segal DS, Aizenstein ML (1991) Amphetamine, cocaine, and fencamfamine: relationship between locomotor and stereotypy response profiles and caudate and accumbens dopamine dynamics. J Neurosci 11:2703-2712
    • (1991) J Neurosci , vol.11 , pp. 2703-2712
    • Kuczenski, R.1    Segal, D.S.2    Aizenstein, M.L.3
  • 110
    • 0034976121 scopus 로고    scopus 로고
    • Chronic treatment with delta(9)-tetrahydrocannabinol enhances the locomotor response to amphetamine and heroin. Implications for vulnerability to drug addiction
    • Lamarque S, Taghzouti K, Simon H (2001) Chronic treatment with delta(9)-tetrahydrocannabinol enhances the locomotor response to amphetamine and heroin. Implications for vulnerability to drug addiction. Neuropharmacology 41:118-129
    • (2001) Neuropharmacology , vol.41 , pp. 118-129
    • Lamarque, S.1    Taghzouti, K.2    Simon, H.3
  • 111
    • 0032766027 scopus 로고    scopus 로고
    • The palmitoylethanolamide and oleamide enigmas: Are these two fatty acid amides cannabimimetic?
    • Lambert DM, Di Marzo V (1999) The palmitoylethanolamide and oleamide enigmas: are these two fatty acid amides cannabimimetic? Curr Med Chem 6:757-773
    • (1999) Curr Med Chem , vol.6 , pp. 757-773
    • Lambert, D.M.1    Di Marzo, V.2
  • 113
    • 0015948729 scopus 로고
    • Failure to obtain "cannabis directed behavior" and abstinence syndrome in rats chronically treated with cannabis sativa extracts
    • Leite JR, Carlini EA (1974) Failure to obtain "cannabis directed behavior" and abstinence syndrome in rats chronically treated with cannabis sativa extracts. Psychopharmacologia 36:133-145
    • (1974) Psychopharmacologia , vol.36 , pp. 133-145
    • Leite, J.R.1    Carlini, E.A.2
  • 114
    • 0029036137 scopus 로고
    • Conditioned place preference induced by Δ9-tetrahydrocannabinol: Comparison with cocaine, morphine, and food reward
    • Lepore M, Vorel SR, Lowinson J, Gardner EL (1995) Conditioned place preference induced by Δ9-tetrahydrocannabinol: comparison with cocaine, morphine, and food reward. Life Sci 56:2073-2080
    • (1995) Life Sci , vol.56 , pp. 2073-2080
    • Lepore, M.1    Vorel, S.R.2    Lowinson, J.3    Gardner, E.L.4
  • 115
    • 0029997038 scopus 로고    scopus 로고
    • 9-tetrahydrocannabinol-induced facilitation of brain stimulation reward as measured by a rate-frequency curve-shift electrical brain stimulation paradigm in three different rat strains
    • 9-tetrahydrocannabinol-induced facilitation of brain stimulation reward as measured by a rate-frequency curve-shift electrical brain stimulation paradigm in three different rat strains. Life Sci (Pharmacol Lett) 58:PL365-PL372
    • (1996) Life Sci (Pharmacol Lett) , vol.58
    • Lepore, M.1    Liu, X.2    Savage, V.3    Matalon, D.4    Gardner, E.L.5
  • 116
    • 0021631637 scopus 로고
    • The partitioning of delta 1-tetrahydrocannabinol into erythrocyte membranes in vivo and its effect on membrane fluidity
    • Leuschner JT, Wing DR, Harvey DJ, Brent GA, Dempsey CE, Watts A, Paton WD (1984) The partitioning of delta 1-tetrahydrocannabinol into erythrocyte membranes in vivo and its effect on membrane fluidity. Experientia 40:866-868
    • (1984) Experientia , vol.40 , pp. 866-868
    • Leuschner, J.T.1    Wing, D.R.2    Harvey, D.J.3    Brent, G.A.4    Dempsey, C.E.5    Watts, A.6    Paton, W.D.7
  • 117
    • 0019417069 scopus 로고
    • Clinical effects and plasma levels of delta 9-tetrahydrocannabinol (delta 9-THC) in heavy and light users of cannabis
    • Lindgren JE, Ohlsson A, Agurell S, Hollister L, Gillespie H (1981) Clinical effects and plasma levels of delta 9-tetrahydrocannabinol (delta 9-THC) in heavy and light users of cannabis. Psychopharmacology 74:208-212
    • (1981) Psychopharmacology , vol.74 , pp. 208-212
    • Lindgren, J.E.1    Ohlsson, A.2    Agurell, S.3    Hollister, L.4    Gillespie, H.5
  • 118
    • 0026560323 scopus 로고
    • Distribution of the neuronal cannabinoid receptor in the adult rat brain: A comparative receptor binding radioautography and in situ hybridization histochemistry
    • Mailleux P, Vanderhaeghen JJ (1992) Distribution of the neuronal cannabinoid receptor in the adult rat brain: a comparative receptor binding radioautography and in situ hybridization histochemistry. Neuroscience 48:655-688
    • (1992) Neuroscience , vol.48 , pp. 655-688
    • Mailleux, P.1    Vanderhaeghen, J.J.2
  • 119
    • 0036669501 scopus 로고    scopus 로고
    • Study of cannabinoid dependence in animals
    • Maldonado R (2002) Study of cannabinoid dependence in animals. Pharmacol Ther 95:153-164
    • (2002) Pharmacol Ther , vol.95 , pp. 153-164
    • Maldonado, R.1
  • 120
    • 0036580701 scopus 로고    scopus 로고
    • Cannabinoid addiction: Behavioral models and neural correlates
    • Maldonado R, Rodriguez de Fonseca F (2002) Cannabinoid addiction: behavioral models and neural correlates. J Neurosci 22:3326-3331
    • (2002) J Neurosci , vol.22 , pp. 3326-3331
    • Maldonado, R.1    Rodriguez De Fonseca, F.2
  • 121
    • 0032557241 scopus 로고    scopus 로고
    • Delta 9-tetrahydrocannabinol, but not the endogenous cannabinoid receptor ligand anandamide, produces conditioned place avoidance
    • Mallet PE, Beninger RJ (1998) Delta 9-tetrahydrocannabinol, but not the endogenous cannabinoid receptor ligand anandamide, produces conditioned place avoidance. Life Sci 62:2431-2439
    • (1998) Life Sci , vol.62 , pp. 2431-2439
    • Mallet, P.E.1    Beninger, R.J.2
  • 122
    • 0028177785 scopus 로고
    • Failure of Δ9-tetrahydrocannabinol and CP 55,940 to maintain intravenous self-administration under a fixed-interval schedule in rhesus monkeys
    • Mansbach RS, Nicholson KL, Martin BR, Balster RL (1994) Failure of Δ9-tetrahydrocannabinol and CP 55,940 to maintain intravenous self-administration under a fixed-interval schedule in rhesus monkeys. Behav Pharmacol 5:219-225
    • (1994) Behav Pharmacol , vol.5 , pp. 219-225
    • Mansbach, R.S.1    Nicholson, K.L.2    Martin, B.R.3    Balster, R.L.4
  • 123
    • 0029933318 scopus 로고    scopus 로고
    • Effects of the cannabinoid CB1 receptor antagonist SR141716A on the behavior of pigeons and rats
    • Mansbach RS, Rovetti CC, Winston EN, Lowe JA III (1996) Effects of the cannabinoid CB1 receptor antagonist SR141716A on the behavior of pigeons and rats. Psychopharmacology 124:315-322
    • (1996) Psychopharmacology , vol.124 , pp. 315-322
    • Mansbach, R.S.1    Rovetti, C.C.2    Winston, E.N.3    Lowe J.A. III4
  • 125
    • 0032579759 scopus 로고    scopus 로고
    • Chronic administration of cannabinoids regulates proenkephalin mRNA levels in selected regions of the rat brain
    • Manzanares J, Corchero J, Romero J, Fernandez-Ruiz JJ, Ramos JA, Fuentes JA (1998) Chronic administration of cannabinoids regulates proenkephalin mRNA levels in selected regions of the rat brain. Mol Brain Res 55:126-132
    • (1998) Mol Brain Res , vol.55 , pp. 126-132
    • Manzanares, J.1    Corchero, J.2    Romero, J.3    Fernandez-Ruiz, J.J.4    Ramos, J.A.5    Fuentes, J.A.6
  • 127
    • 0032495834 scopus 로고    scopus 로고
    • Self-administration of the cannabinoid receptor agonist WIN 55,212-2 in drug-naive mice
    • Martellotta MC, Cossu G, Fattore L, Gessa GL, Fratta W (1998) Self-administration of the cannabinoid receptor agonist WIN 55,212-2 in drug-naive mice. Neuroscience 85:327-330
    • (1998) Neuroscience , vol.85 , pp. 327-330
    • Martellotta, M.C.1    Cossu, G.2    Fattore, L.3    Gessa, G.L.4    Fratta, W.5
  • 128
    • 0036260750 scopus 로고    scopus 로고
    • Identification of the endogenous cannabinoid system through integrative pharmacological approaches
    • Martin BR (2002) Identification of the endogenous cannabinoid system through integrative pharmacological approaches. J Pharmacol Exp Ther 301:790-796
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 790-796
    • Martin, B.R.1
  • 129
    • 0032459476 scopus 로고    scopus 로고
    • Cannabinoid transmission and pain perception
    • Martin BR, Lichtman AH (1998) Cannabinoid transmission and pain perception. Neurobiol Dis 5:447-461
    • (1998) Neurobiol Dis , vol.5 , pp. 447-461
    • Martin, B.R.1    Lichtman, A.H.2
  • 130
    • 0033538561 scopus 로고    scopus 로고
    • Discovery and characterization of endogenous cannabinoids
    • Martin BR, Mechoulam R, Razdan RK (1999) Discovery and characterization of endogenous cannabinoids. Life Sci 65:573-595
    • (1999) Life Sci , vol.65 , pp. 573-595
    • Martin, B.R.1    Mechoulam, R.2    Razdan, R.K.3
  • 131
    • 0033777338 scopus 로고    scopus 로고
    • Cocaine, but not morphine, induces conditioned place preference and sensitization to locomotor responses in CB1 knockout mice
    • Martin M, Ledent C, Parmentier M, Maldonado R, Valverde O (2000) Cocaine, but not morphine, induces conditioned place preference and sensitization to locomotor responses in CB1 knockout mice. Eur J Neurosci 12:4038-4046
    • (2000) Eur J Neurosci , vol.12 , pp. 4038-4046
    • Martin, M.1    Ledent, C.2    Parmentier, M.3    Maldonado, R.4    Valverde, O.5
  • 133
    • 0035040970 scopus 로고    scopus 로고
    • Reduction of opioid dependence by the CB(1) antagonist SR141716A in mice: Evaluation of the interest in pharmacotherapy of opioid addiction
    • Mas-Nieto M, Pommier B, Tzavara ET, Caneparo A, Da Nascimento S, Le Fur G, Roques BP, Noble F (2001) Reduction of opioid dependence by the CB(1) antagonist SR141716A in mice: evaluation of the interest in pharmacotherapy of opioid addiction. Br J Pharmacol 132:1809-1816
    • (2001) Br J Pharmacol , vol.132 , pp. 1809-1816
    • Mas-Nieto, M.1    Pommier, B.2    Tzavara, E.T.3    Caneparo, A.4    Da Nascimento, S.5    Le Fur, G.6    Roques, B.P.7    Noble, F.8
  • 135
    • 0025325535 scopus 로고
    • Structure of a cannabinoid receptor and functional expression of the cloned cDNA
    • Matsuda LA, Lolait SJ, Brownstein MJ, Young AC, Bonner TI (1990) Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346:561-564
    • (1990) Nature , vol.346 , pp. 561-564
    • Matsuda, L.A.1    Lolait, S.J.2    Brownstein, M.J.3    Young, A.C.4    Bonner, T.I.5
  • 136
    • 0030005172 scopus 로고    scopus 로고
    • Aversive effects of the synthetic cannabinoid CP 55,940 in rats
    • McGregor IS, Issakidis CN, Prior G (1996) Aversive effects of the synthetic cannabinoid CP 55,940 in rats. Pharmacol Biochem Behav 53:657-664
    • (1996) Pharmacol Biochem Behav , vol.53 , pp. 657-664
    • McGregor, I.S.1    Issakidis, C.N.2    Prior, G.3
  • 138
    • 0029117641 scopus 로고
    • Increase of extracellular corticotropin-releasing factor-like immunoreactivity levels in the amygdala of awake rats during restraint stress and ethanol withdrawal as measured by microdialysis
    • Merlo Pich E, Lorang M, Yeganeh M, de Fonseca FR, Raber J, Koob GF, Weiss F (1995) Increase of extracellular corticotropin-releasing factor-like immunoreactivity levels in the amygdala of awake rats during restraint stress and ethanol withdrawal as measured by microdialysis. J Neurosci 15:5439-5447
    • (1995) J Neurosci , vol.15 , pp. 5439-5447
    • Merlo Pich, E.1    Lorang, M.2    Yeganeh, M.3    De Fonseca, F.R.4    Raber, J.5    Koob, G.F.6    Weiss, F.7
  • 139
    • 0022530231 scopus 로고
    • The role of benzodiazepine receptors in the discriminative stimulus properties of delta-9-tetrahydrocannabinol
    • Mokler DJ, Nelson BD, Harris LS, Rosecrans JA (1986) The role of benzodiazepine receptors in the discriminative stimulus properties of delta-9-tetrahydrocannabinol. Life Sci 38:1581-1589
    • (1986) Life Sci , vol.38 , pp. 1581-1589
    • Mokler, D.J.1    Nelson, B.D.2    Harris, L.S.3    Rosecrans, J.A.4
  • 140
    • 0034881533 scopus 로고    scopus 로고
    • Effects of chronic Delta(9)-tetrahydrocannabinol treatment on hippocampal extracellular acetylcholine concentration and alternation performance in the T-maze
    • Nava F, Carta G, Colombo G, Gessa GL (2001) Effects of chronic Delta(9)-tetrahydrocannabinol treatment on hippocampal extracellular acetylcholine concentration and alternation performance in the T-maze. Neuropharmacology 41:392-329
    • (2001) Neuropharmacology , vol.41 , pp. 392-329
    • Nava, F.1    Carta, G.2    Colombo, G.3    Gessa, G.L.4
  • 141
    • 0027381695 scopus 로고
    • An acute dose of delta 9-tetrahydrocannabinol affects behavioral and neurochemical indices of mesolimbic dopaminergic activity
    • Navarro M, Fernandez-Ruiz JJ, de Miguel R, Hernandez ML, Cebeira M, Ramos JA (1993) An acute dose of delta 9-tetrahydrocannabinol affects behavioral and neurochemical indices of mesolimbic dopaminergic activity. Behav Brain Res 57:37-46
    • (1993) Behav Brain Res , vol.57 , pp. 37-46
    • Navarro, M.1    Fernandez-Ruiz, J.J.2    De Miguel, R.3    Hernandez, M.L.4    Cebeira, M.5    Ramos, J.A.6
  • 144
    • 0017690077 scopus 로고
    • Tolerance to marijuana: Heart rate and subjective "high."
    • Nowlan R, Cohen S (1977) Tolerance to marijuana: heart rate and subjective "high." Clin Pharmacol Ther 22:550-556
    • (1977) Clin Pharmacol Ther , vol.22 , pp. 550-556
    • Nowlan, R.1    Cohen, S.2
  • 145
    • 0019438741 scopus 로고
    • The central basis of motivation: Intracranial self-stimulation studies
    • Olds ME, Fobes JL (1981) The central basis of motivation: intracranial self-stimulation studies. Ann Rev Psychol 32:523-574
    • (1981) Ann Rev Psychol , vol.32 , pp. 523-574
    • Olds, M.E.1    Fobes, J.L.2
  • 146
    • 33645367848 scopus 로고
    • Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain
    • Olds J, Milner P (1954) Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain. J Comp Physiol Psychol 47:419-427
    • (1954) J Comp Physiol Psychol , vol.47 , pp. 419-427
    • Olds, J.1    Milner, P.2
  • 147
    • 0027196816 scopus 로고
    • Chronic cannabinoid administration alters cannabinoid receptor binding in rat brain: A quantitative autoradiographic study
    • Oviedo A, Glowa J, Herkenham M (1993) Chronic cannabinoid administration alters cannabinoid receptor binding in rat brain: a quantitative autoradiographic study. Brain Res 616:293-302
    • (1993) Brain Res , vol.616 , pp. 293-302
    • Oviedo, A.1    Glowa, J.2    Herkenham, M.3
  • 149
    • 0031863866 scopus 로고    scopus 로고
    • Effects of delivery rate and non-contingent infusion of cocaine on cocaineself-administration in rhesus monkeys
    • Panlilio LV, Goldberg SR, Gilman JP, Jufer R, Cone EJ, Schindler CW (1998) Effects of delivery rate and non-contingent infusion of cocaine on cocaineself-administration in rhesus monkeys. Psychopharmacology 137:253-258
    • (1998) Psychopharmacology , vol.137 , pp. 253-258
    • Panlilio, L.V.1    Goldberg, S.R.2    Gilman, J.P.3    Jufer, R.4    Cone, E.J.5    Schindler, C.W.6
  • 150
    • 0016416351 scopus 로고
    • Pharmacology of marijuana
    • Paton WD (1975) Pharmacology of marijuana. Annu Rev Pharmacol 15:191-220
    • (1975) Annu Rev Pharmacol , vol.15 , pp. 191-220
    • Paton, W.D.1
  • 153
    • 0032802188 scopus 로고    scopus 로고
    • Pharmacology of cannabinoid receptor ligands
    • Pertwee RG (1999) Pharmacology of cannabinoid receptor ligands. Curr Med Chem 6:635-664
    • (1999) Curr Med Chem , vol.6 , pp. 635-664
    • Pertwee, R.G.1
  • 154
    • 0027442538 scopus 로고
    • Cross-tolerance between delta-9-tetrahydrocannabinol and the cannabimimetic agents, CP 55,940, WIN 55,212-2 and anandamide
    • Pertwee RG, Stevenson LA, Griffin G (1993) Cross-tolerance between delta-9-tetrahydrocannabinol and the cannabimimetic agents, CP 55,940, WIN 55,212-2 and anandamide. Br J Pharmacol 110:1483-1490
    • (1993) Br J Pharmacol , vol.110 , pp. 1483-1490
    • Pertwee, R.G.1    Stevenson, L.A.2    Griffin, G.3
  • 155
    • 0002516379 scopus 로고
    • Cannabis and phencyclidine self-administered by animals
    • Goldfarb L, Hoffmeister F (eds). Springer, Berlin Heidelberg New York
    • Pickens R, Thompson T, Muchow DC (1973) Cannabis and phencyclidine self-administered by animals. In: Goldfarb L, Hoffmeister F (eds) Psychic dependence [Bayer-Symposium IV]. Springer, Berlin Heidelberg New York, pp 78-86
    • (1973) Psychic Dependence [Bayer-Symposium IV] , pp. 78-86
    • Pickens, R.1    Thompson, T.2    Muchow, D.C.3
  • 158
    • 0029583656 scopus 로고
    • Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens
    • Pontieri FE, Tanda G, Di Chiara G (1995) Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens. Proc Natl Acad Sci USA 92:12304-12308
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 12304-12308
    • Pontieri, F.E.1    Tanda, G.2    Di Chiara, G.3
  • 159
    • 0029943635 scopus 로고    scopus 로고
    • Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs
    • Pontieri FE, Tanda G, Orzi F, Di Chiara G (1996) Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs. Nature 382:255-257
    • (1996) Nature , vol.382 , pp. 255-257
    • Pontieri, F.E.1    Tanda, G.2    Orzi, F.3    Di Chiara, G.4
  • 162
    • 0030070793 scopus 로고    scopus 로고
    • The residual cognitive effects of heavy marijuana use in college students
    • Pope HG, Yurgelun-Todd D (1996) The residual cognitive effects of heavy marijuana use in college students. JAMA 275:521-527
    • (1996) JAMA , vol.275 , pp. 521-527
    • Pope, H.G.1    Yurgelun-Todd, D.2
  • 165
    • 0021245951 scopus 로고
    • Brain stimulation reward and dopamine terminal fields: I. Caudate-putamen, nucleus accumbens and amygdala
    • Prado-Alcala R, Wise RA (1984) Brain stimulation reward and dopamine terminal fields: I. caudate-putamen, nucleus accumbens and amygdala. Brain Res 297:265-273
    • (1984) Brain Res , vol.297 , pp. 265-273
    • Prado-Alcala, R.1    Wise, R.A.2
  • 166
    • 0028968749 scopus 로고
    • Sensitization of cocaine-stimulated increase in extracellular levels of corticotropin-releasing factor from the rat amygdala after repeated administration as determined by intracranial microdialysis
    • Richter RM, Pich EM, Koob GF, Weiss F (1995) Sensitization of
    • (1995) Neurosci Lett , vol.187 , pp. 169-172
    • Richter, R.M.1    Pich, E.M.2    Koob, G.F.3    Weiss, F.4
  • 167
    • 0033563987 scopus 로고    scopus 로고
    • In vivo CRF release in rat amygdala is increased during cocaine withdrawal in self-administering rats
    • Richter RM, Weiss F (1999) In vivo CRF release in rat amygdala is increased during cocaine withdrawal in self-administering rats. Synapse 32:254-261
    • (1999) Synapse , vol.32 , pp. 254-261
    • Richter, R.M.1    Weiss, F.2
  • 169
    • 0027305458 scopus 로고
    • The neural basis of drug craving: An incentive-sensitization theory of addiction
    • Robinson TE, Berridge KC (1993) The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res Brain Res Rev 18:247-291
    • (1993) Brain Res Brain Res Rev , vol.18 , pp. 247-291
    • Robinson, T.E.1    Berridge, K.C.2
  • 170
    • 0035139761 scopus 로고    scopus 로고
    • Incentive-sensitization and addiction
    • Robinson TE, Berridge KC (2001) Incentive-sensitization and addiction. Addiction 96:103-114
    • (2001) Addiction , vol.96 , pp. 103-114
    • Robinson, T.E.1    Berridge, K.C.2
  • 171
    • 0030959336 scopus 로고    scopus 로고
    • Effects of chronic exposure to delta9-tetrahydrocannabinol on cannabinoid receptor binding and mRNA levels in several rat brain regions
    • Romero J, Garcia-Palomero E, Castro JG, Garcia-Gil L, Ramos JA, Fernandez-Ruiz JJ (1997) Effects of chronic exposure to delta9-tetrahydrocannabinol on cannabinoid receptor binding and mRNA levels in several rat brain regions. Brain Res Mol Brain Res 46:100-108
    • (1997) Brain Res Mol Brain Res , vol.46 , pp. 100-108
    • Romero, J.1    Garcia-Palomero, E.2    Castro, J.G.3    Garcia-Gil, L.4    Ramos, J.A.5    Fernandez-Ruiz, J.J.6
  • 172
    • 0031669975 scopus 로고    scopus 로고
    • Time-course of the cannabinoid receptor down-regulation in the adult rat brain caused by repeated exposure to delta 9-tetrahydrocannabinol
    • Romero J, Berrendero F, Manzanares J, Perez A, Corchero J, Fuentes A, Fernandez-Ruiz JJ, Ramos JA (1998) Time-course of the cannabinoid receptor down-regulation in the adult rat brain caused by repeated exposure to delta 9-tetrahydrocannabinol. Synapse 30:298-308
    • (1998) Synapse , vol.30 , pp. 298-308
    • Romero, J.1    Berrendero, F.2    Manzanares, J.3    Perez, A.4    Corchero, J.5    Fuentes, A.6    Fernandez-Ruiz, J.J.7    Ramos, J.A.8
  • 174
    • 0025799458 scopus 로고
    • Marked decrease of extraneuronal dopamine after alcohol withdrawal in rats: Reversal by MK-801
    • Rossetti ZL, Melis F, Carboni S, Gessa GL (1991) Marked decrease of extraneuronal dopamine after alcohol withdrawal in rats: reversal by MK-801. Eur J Pharmacol 200:371-372
    • (1991) Eur J Pharmacol , vol.200 , pp. 371-372
    • Rossetti, Z.L.1    Melis, F.2    Carboni, S.3    Gessa, G.L.4
  • 175
    • 0026722616 scopus 로고
    • Marked inhibition of mesolimbic dopamine release: A common feature of ethanol, morphine, cocaine and amphetamine abstinence in rats
    • Rossetti ZL, Hmaidan Y, Gessa GL (1992a) Marked inhibition of mesolimbic dopamine release: a common feature of ethanol, morphine, cocaine and amphetamine abstinence in rats. Eur J Pharmacol 221:227-234
    • (1992) Eur J Pharmacol , vol.221 , pp. 227-234
    • Rossetti, Z.L.1    Hmaidan, Y.2    Gessa, G.L.3
  • 176
    • 0026673367 scopus 로고
    • Dramatic depletion of mesolimbic extracellular dopamine after withdrawal from morphine, alcohol or cocaine: A common neurochemical substrate for drug dependence
    • Rossetti ZL, Melis F, Carboni S, Gessa GL (1992b) Dramatic depletion of mesolimbic extracellular dopamine after withdrawal from morphine, alcohol or cocaine: a common neurochemical substrate for drug dependence. Ann NY Acad Sci 654:513-526
    • (1992) Ann NY Acad Sci , vol.654 , pp. 513-526
    • Rossetti, Z.L.1    Melis, F.2    Carboni, S.3    Gessa, G.L.4
  • 177
    • 0031055103 scopus 로고    scopus 로고
    • Chronic treatment with a synthetic cannabinoid CP-55,940 alters G-protein expression in the rat central nervous system
    • Rubino T, Patrini G, Parenti M, Massi P, Parolaro D (1997a) Chronic treatment with a synthetic cannabinoid CP-55,940 alters G-protein expression in the rat central nervous system. Brain Res Mol Brain Res 44:191-197
    • (1997) Brain Res Mol Brain Res , vol.44 , pp. 191-197
    • Rubino, T.1    Patrini, G.2    Parenti, M.3    Massi, P.4    Parolaro, D.5
  • 178
    • 0030779485 scopus 로고    scopus 로고
    • Modulation of rat brain cannabinoid receptors after chronic morphine treatment
    • Rubino T, Tizzoni L, Vigano D, Massi P, Parolaro D (1997b) Modulation of rat brain cannabinoid receptors after chronic morphine treatment. Neuroreport 8:3219-3223
    • (1997) Neuroreport , vol.8 , pp. 3219-3223
    • Rubino, T.1    Tizzoni, L.2    Vigano, D.3    Massi, P.4    Parolaro, D.5
  • 179
    • 84906849432 scopus 로고    scopus 로고
    • The psychoactive ingredient of marijuana induces behavioural sensitization
    • Rubino T, Vigano D, Massi P, Parolaro D (2001) The psychoactive ingredient of marijuana induces behavioural sensitization. Eur J Neurosci 14:884-886
    • (2001) Eur J Neurosci , vol.14 , pp. 884-886
    • Rubino, T.1    Vigano, D.2    Massi, P.3    Parolaro, D.4
  • 183
    • 0036269429 scopus 로고    scopus 로고
    • A review of the published literature into cannabis withdrawal symptoms in human users
    • Smith NT (2002) A review of the published literature into cannabis withdrawal symptoms in human users. Addiction 97:621-632
    • (2002) Addiction , vol.97 , pp. 621-632
    • Smith, N.T.1
  • 184
    • 0028261433 scopus 로고
    • Interactions between Δ9-tetrahydrocannabinol and kappa opioids in mice
    • Smith PB, Welch SP, Martin BR (1994) Interactions between Δ9-tetrahydrocannabinol and kappa opioids in mice. J Pharmacol Exp Ther 268:1381-1387
    • (1994) J Pharmacol Exp Ther , vol.268 , pp. 1381-1387
    • Smith, P.B.1    Welch, S.P.2    Martin, B.R.3
  • 185
    • 0018641072 scopus 로고
    • Self-administration of Δ9-tetrahydrocannabinol by rats
    • Takahashi RN, Singer G (1979) Self-administration of Δ 9-tetrahydrocannabinol by rats. Pharmacol Biochem Behav 11:737-740
    • (1979) Pharmacol Biochem Behav , vol.11 , pp. 737-740
    • Takahashi, R.N.1    Singer, G.2
  • 186
    • 0019156216 scopus 로고
    • Effects of body weight levels on cannabis self-administration
    • Takahashi RN, Singer G (1980) Effects of body weight levels on cannabis self-administration. Pharmacol Biochem Behav 13:877-881
    • (1980) Pharmacol Biochem Behav , vol.13 , pp. 877-881
    • Takahashi, R.N.1    Singer, G.2
  • 188
    • 0032988722 scopus 로고    scopus 로고
    • Dependence of mesolimbic dopamine transmission on delta9-tetrahydrocannabinol
    • Tanda G, Loddo P, Di Chiara G (1999) Dependence of mesolimbic dopamine transmission on delta9-tetrahydrocannabinol. Eur J Pharmacol 376:23-26
    • (1999) Eur J Pharmacol , vol.376 , pp. 23-26
    • Tanda, G.1    Loddo, P.2    Di Chiara, G.3
  • 189
    • 0033773866 scopus 로고    scopus 로고
    • Self-administration behavior is maintained by the psychoactive ingredient of marijuana in squirrel monkeys
    • Tanda G, Munzar P, Goldberg SR (2000) Self-administration behavior is maintained by the psychoactive ingredient of marijuana in squirrel monkeys. Nature Neurosci 3:1073-1074
    • (2000) Nature Neurosci , vol.3 , pp. 1073-1074
    • Tanda, G.1    Munzar, P.2    Goldberg, S.R.3
  • 191
    • 0029643521 scopus 로고
    • Physical withdrawal in rats tolerant to delta 9-tetrahydrocannabinol precipitated by a cannabinoid receptor antagonist
    • Tsou K, Patrick SL, Walker JM (1995) Physical withdrawal in rats tolerant to delta 9-tetrahydrocannabinol precipitated by a cannabinoid receptor antagonist. Eur J Pharmacol 280:R13-R15
    • (1995) Eur J Pharmacol , vol.280
    • Tsou, K.1    Patrick, S.L.2    Walker, J.M.3
  • 192
    • 0032436807 scopus 로고    scopus 로고
    • Measuring reward with the conditioned place preference paradigm: A comprehensive review of drug effects, recent progress and new issues
    • Tzschentke TM (1998) Measuring reward with the conditioned place preference paradigm: a comprehensive review of drug effects, recent progress and new issues. Prog Neurobiol 56:613-672
    • (1998) Prog Neurobiol , vol.56 , pp. 613-672
    • Tzschentke, T.M.1
  • 194
    • 0034671190 scopus 로고    scopus 로고
    • Cannabinoid withdrawal syndrome is reduced in preproenkephalin knock-out mice
    • Valverde O, Maldonado R, Valjent E, Zimmer AM, Zimmer A (2000) Cannabinoid withdrawal syndrome is reduced in preproenkephalin knock-out mice. J Neurosci 20:9284-9289
    • (2000) J Neurosci , vol.20 , pp. 9284-9289
    • Valverde, O.1    Maldonado, R.2    Valjent, E.3    Zimmer, A.M.4    Zimmer, A.5
  • 195
    • 0034744088 scopus 로고    scopus 로고
    • Delta9-tetrahydrocannabinol releases and facilitates the effects of endogenous enkephalins: Reduction in morphine withdrawal syndrome without change in rewarding effect
    • Valverde O, Noble F, Beslot F, Dauge V, Fournie-Zaluski MC, Roques BP (2001) Delta9-tetrahydrocannabinol releases and facilitates the effects of endogenous enkephalins: reduction in morphine withdrawal syndrome without change in rewarding effect. Eur J Neurosci 13:1816-1824
    • (2001) Eur J Neurosci , vol.13 , pp. 1816-1824
    • Valverde, O.1    Noble, F.2    Beslot, F.3    Dauge, V.4    Fournie-Zaluski, M.C.5    Roques, B.P.6
  • 197
    • 0029048756 scopus 로고
    • Anandamide decreases naloxone-precipitated withdrawal signs in mice chronically treated with morphine
    • Vela G, Ruiz-Gayo M, Fuentes JA (1995) Anandamide decreases naloxone-precipitated withdrawal signs in mice chronically treated with morphine. Neuropharmacology 34:665-668
    • (1995) Neuropharmacology , vol.34 , pp. 665-668
    • Vela, G.1    Ruiz-Gayo, M.2    Fuentes, J.A.3
  • 199
    • 0034213769 scopus 로고    scopus 로고
    • Naltrexone does not block the subjective effects of oral Delta(9)-tetrahydrocannabinol in humans
    • Wachtel SR, de Wit H (2000) Naltrexone does not block the subjective effects of oral Delta(9)-tetrahydrocannabinol in humans. Drug Alcohol Depend 59:251-260
    • (2000) Drug Alcohol Depend , vol.59 , pp. 251-260
    • Wachtel, S.R.1    De Wit, H.2
  • 200
    • 0028957453 scopus 로고
    • Reinforcing effect as a function of infusion speed in intravenous self-administration of nicotine in rhesus monkeys
    • Wakasa Y, Takada K, Yanagita T (1995) Reinforcing effect as a function of infusion speed in intravenous self-administration of nicotine in rhesus monkeys. Nihon Shinkei Seishin Yakurigaku Zasshi 15:53-59
    • (1995) Nihon Shinkei Seishin Yakurigaku Zasshi , vol.15 , pp. 53-59
    • Wakasa, Y.1    Takada, K.2    Yanagita, T.3
  • 202
    • 0037207087 scopus 로고    scopus 로고
    • Endocannabinoids and related fatty acid derivatives in pain modulation
    • Walker JM, Krey JF, Chu CJ, Huang SM (2002) Endocannabinoids and related fatty acid derivatives in pain modulation. Chem Phys Lipids 121:159-172
    • (2002) Chem Phys Lipids , vol.121 , pp. 159-172
    • Walker, J.M.1    Krey, J.F.2    Chu, C.J.3    Huang, S.M.4
  • 203
    • 0030975023 scopus 로고    scopus 로고
    • Characterization of anandamide-induced tolerance: Comparison to delta 9-THC-induced interactions with dynorphinergic systems
    • Welch SP (1997) Characterization of anandamide-induced tolerance: comparison to delta 9-THC-induced interactions with dynorphinergic systems. Drug Alcohol Depend 45:39-45
    • (1997) Drug Alcohol Depend , vol.45 , pp. 39-45
    • Welch, S.P.1
  • 204
    • 0032822969 scopus 로고    scopus 로고
    • Cannabis: Discrimination of "internal bliss"?
    • Wiley JL (1999) Cannabis: discrimination of "internal bliss"? Pharmacol Biochem Behav 64:257-260
    • (1999) Pharmacol Biochem Behav , vol.64 , pp. 257-260
    • Wiley, J.L.1
  • 205
    • 0032847529 scopus 로고    scopus 로고
    • Effects of SR141716A on diazepam substitution for delta9-tetrahydrocannabinol in rat drug discrimination
    • Wiley JL, Martin BR (1999) Effects of SR141716A on diazepam substitution for delta9-tetrahydrocannabinol in rat drug discrimination. Pharmacol Biochem Behav 64:519-522
    • (1999) Pharmacol Biochem Behav , vol.64 , pp. 519-522
    • Wiley, J.L.1    Martin, B.R.2
  • 206
    • 0027133532 scopus 로고
    • Tolerance to the discriminative stimulus effects of delta(9)-tetrahydrocannabinol
    • Wiley JL, Barrett RL, Balster RL, Martin BR (1993a) Tolerance to the discriminative stimulus effects of delta(9)-tetrahydrocannabinol. Behav Pharmacol 4:581-585
    • (1993) Behav Pharmacol , vol.4 , pp. 581-585
    • Wiley, J.L.1    Barrett, R.L.2    Balster, R.L.3    Martin, B.R.4
  • 207
    • 0027456885 scopus 로고
    • Discriminative stimulus effects of delta 9-tetrahydrocannabinol and delta 9-11-tetrahydrocannabinol in rats and rhesus monkeys
    • Wiley JL, Barrett RL, Britt DT, Balster RL, Martin BR (1993b) Discriminative stimulus effects of delta 9-tetrahydrocannabinol and delta 9-11-tetrahydrocannabinol in rats and rhesus monkeys. Neuropharmacology 32:359-365
    • (1993) Neuropharmacology , vol.32 , pp. 359-365
    • Wiley, J.L.1    Barrett, R.L.2    Britt, D.T.3    Balster, R.L.4    Martin, B.R.5
  • 208
    • 0028961790 scopus 로고
    • Discriminative stimulus effects of anandamide in rats
    • Wiley JL, Balster RL, Martin BR (1995a) Discriminative stimulus effects of anandamide in rats. Eur J Pharmacol 276:49-54
    • (1995) Eur J Pharmacol , vol.276 , pp. 49-54
    • Wiley, J.L.1    Balster, R.L.2    Martin, B.R.3
  • 209
    • 0029079240 scopus 로고
    • Discriminative stimulus effects of CP 55,940 and structurally dissimilar cannabinoids in rats
    • Wiley JL, Barrett RL, Lowe J, Balster RL, Martin BR (1995b) Discriminative stimulus effects of CP 55,940 and structurally dissimilar cannabinoids in rats. Neuropharmacology 34:669-676
    • (1995) Neuropharmacology , vol.34 , pp. 669-676
    • Wiley, J.L.1    Barrett, R.L.2    Lowe, J.3    Balster, R.L.4    Martin, B.R.5
  • 210
    • 0028879450 scopus 로고
    • Pharmacological specificity of the discriminative stimulus effects of Δ9-tetrahydrocannabinol in rhesus monkeys
    • Wiley JL, Huffman JW, Balster RL, Martin BR (1995c) Pharmacological specificity of the discriminative stimulus effects of Δ 9-tetrahydrocannabinol in rhesus monkeys. Drug Alcohol Depend 40:81-86
    • (1995) Drug Alcohol Depend , vol.40 , pp. 81-86
    • Wiley, J.L.1    Huffman, J.W.2    Balster, R.L.3    Martin, B.R.4
  • 211
    • 0031415862 scopus 로고    scopus 로고
    • Evaluation of cannabimimetic discriminative stimulus effects of anandamide and methylated fluoroanandamide in rhesus monkeys
    • Wiley JL, Golden KM, Ryan WJ, Balster RL, Razdan RK, Martin BR (1997) Evaluation of cannabimimetic discriminative stimulus effects of anandamide and methylated fluoroanandamide in rhesus monkeys. Pharmacol Biochem Behav 58:1139-1143
    • (1997) Pharmacol Biochem Behav , vol.58 , pp. 1139-1143
    • Wiley, J.L.1    Golden, K.M.2    Ryan, W.J.3    Balster, R.L.4    Razdan, R.K.5    Martin, B.R.6
  • 212
    • 0031665875 scopus 로고    scopus 로고
    • Evaluation of cannabimimetic effects of structural analogs of anandamide in rats
    • Wiley JL, Ryan WJ, Razdan RK, Martin BR (1998) Evaluation of cannabimimetic effects of structural analogs of anandamide in rats. Eur J Pharmacol 355:113-118
    • (1998) Eur J Pharmacol , vol.355 , pp. 113-118
    • Wiley, J.L.1    Ryan, W.J.2    Razdan, R.K.3    Martin, B.R.4
  • 213
    • 0023548708 scopus 로고
    • The role of reward pathways in the development of drug dependence
    • Wise RA (1987) The role of reward pathways in the development of drug dependence. Pharmacol Ther 35:227-263
    • (1987) Pharmacol Ther , vol.35 , pp. 227-263
    • Wise, R.A.1
  • 214
    • 0029879993 scopus 로고    scopus 로고
    • Addictive drugs and brain stimulation reward
    • Wise RA (1996) Addictive drugs and brain stimulation reward. Annu Rev Neurosci 19:319-340
    • (1996) Annu Rev Neurosci , vol.19 , pp. 319-340
    • Wise, R.A.1
  • 215
    • 0020025028 scopus 로고
    • Classification of narcotics on the basis of their reinforcing, discriminative, and antagonist effects in rhesus monkeys
    • Woods JH, Young AM, Herling S (1982) Classification of narcotics on the basis of their reinforcing, discriminative, and antagonist effects in rhesus monkeys. Federal Proceedings 41:221-227
    • (1982) Federal Proceedings , vol.41 , pp. 221-227
    • Woods, J.H.1    Young, A.M.2    Herling, S.3
  • 216
    • 0033622131 scopus 로고    scopus 로고
    • Effects of chronic delta9-tetrahydrocannabinol on rat midbrain dopamine neurons: An electrophysiological assessment
    • Wu X, French ED (2000) Effects of chronic delta9-tetrahydrocannabinol on rat midbrain dopamine neurons: an electrophysiological assessment. Neuropharmacology 39:391-398
    • (2000) Neuropharmacology , vol.39 , pp. 391-398
    • Wu, X.1    French, E.D.2
  • 217
    • 0002527967 scopus 로고
    • Intravenous self-administration: Response rates, the effects of pharmacological challenges, and drug preference
    • Bozarth MA (ed). Springer, Berlin Heidelberg New York
    • Yokel RA (1987) Intravenous self-administration: response rates, the effects of pharmacological challenges, and drug preference. In: Bozarth MA (ed) Methods of assessing the reinforcing properties of abused drugs. Springer, Berlin Heidelberg New York, pp 1-33
    • (1987) Methods of Assessing the Reinforcing Properties of Abused Drugs , pp. 1-33
    • Yokel, R.A.1
  • 218
    • 0001768640 scopus 로고
    • Drugs as reinforcers: Studies in laboratory animals
    • Goldberg SR, Stolerman IP (eds). Academic Press, Orlando, FL
    • Young AM, Herling S (1986) Drugs as reinforcers: studies in laboratory animals. In: Goldberg SR, Stolerman IP (eds) Behavioral analysis of drug dependence. Academic Press, Orlando, FL, pp 9-67
    • (1986) Behavioral Analysis of Drug Dependence , pp. 9-67
    • Young, A.M.1    Herling, S.2
  • 219
    • 0019732039 scopus 로고
    • History of drug exposure as a determinant of drug self administration
    • Thompson T, Johanson CE (eds) Behavioral pharmacology of human drug dependence, Washington, DC
    • Young AM, Herling S, Woods JH (1981a) History of drug exposure as a determinant of drug self administration. In: Thompson T, Johanson CE (eds) Behavioral pharmacology of human drug dependence. NIDA research monograph, Washington, DC, 37:75-89
    • (1981) NIDA Research Monograph , vol.37 , pp. 75-89
    • Young, A.M.1    Herling, S.2    Woods, J.H.3
  • 220
    • 0019732704 scopus 로고
    • Comparison of discriminative and reinforcing effects of ketamine and related compounds in the rhesus monkey
    • Harris LS (ed) Problems of drug dependence, Washington, DC
    • Young AM, Herling S, Winger GD, Woods JH (1981b) Comparison of discriminative and reinforcing effects of ketamine and related compounds in the rhesus monkey. In: Harris LS (ed) Problems of drug dependence. NIDA research monograph, Washington, DC, 34:173-179
    • (1981) NIDA Research Monograph , vol.34 , pp. 173-179
    • Young, A.M.1    Herling, S.2    Winger, G.D.3    Woods, J.H.4
  • 222
    • 0033545866 scopus 로고    scopus 로고
    • Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice
    • Zimmer A, Zimmer AM, Hohmann AG, Herkenham M, Bonner TI (1999) Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice. Proc Natl Acad Sci USA 96:5780-5785
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 5780-5785
    • Zimmer, A.1    Zimmer, A.M.2    Hohmann, A.G.3    Herkenham, M.4    Bonner, T.I.5
  • 224
    • 0036617759 scopus 로고    scopus 로고
    • Delta 9-tetrahydrocannabinol and cannabinol activate capsaicin-sensitive sensory nerves via a CB1 and CB2 cannabinoid receptor-independent mechanism
    • Zygmunt PM, Andersson DA, Hogestatt ED (2002) Delta 9-tetrahydrocannabinol and cannabinol activate capsaicin-sensitive sensory nerves via a CB1 and CB2 cannabinoid receptor-independent mechanism. J Neurosci 22:4720-4727
    • (2002) J Neurosci , vol.22 , pp. 4720-4727
    • Zygmunt, P.M.1    Andersson, D.A.2    Hogestatt, E.D.3


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