Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5

Neuroscience

Volumn 116, Issue 1, 2003, Pages 19-22

  Norrholm, S D ^a   Bibb, J A ^b,c   Nestler, E J ^c   Ouimet, C C ^a   Taylor, J R ^d   Greengard, P ^b  

^a FLORIDA STATE UNIVERSITY   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Dendritic morphology; Psychostimulant abuse; Synaptic plasticity

Indexed keywords

COCAINE; CYCLIN DEPENDENT KINASE 5; CYCLIN DEPENDENT KINASE INHIBITOR; ROSCOVITINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATTENUATION; BRAIN REGION; CELL PROLIFERATION; CONTROLLED STUDY; DENDRITIC SPINE; ENZYME ACTIVITY; GOLGI STAIN; LONG TERM EXPOSURE; MALE; NERVE CELL PLASTICITY; NERVE FUNCTION; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT;

ANIMALS; COCAINE; CYCLIN-DEPENDENT KINASE 5; CYCLIN-DEPENDENT KINASES; DENDRITES; DOPAMINE UPTAKE INHIBITORS; ENZYME INHIBITORS; MALE; MICROSCOPY, CONFOCAL; NEURONS; NUCLEUS ACCUMBENS; PURINES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0345894315     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(02)00560-2     Document Type: Article

References (21)

1. Bibb J.A., Chen J., Taylor J.R., Svenningson P., Nishi A., Snyder G.L., Yan Z., Sagawa Z.K., Ouimet C.C., Nairn A.C., Nestler E.J., Greengard P. Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5. Nature. 410:2001;376-380.
2. Bibb J.A., Nishi A., O'Callaghan J.P., Ule J., Lan M., Snyder G.L., Horiuchi A., Saito T., Hisanaga T., Czernik A.J., Nairn A.C., Greengard P.G. Phosphorylation of Protein Phosphatase Inhibitor-1 by Cdk5. J Biol Chem. 276:1999;14490-14497.
3. Bibb J.A., Snyder G.L., Nishi A., Yan Z., Meijer L., Fienberg A.A., Tsai L., Kwon Y.T., Girault J., Czernik A.J., Huganir R.L., Hemmings H.C., Nairn A., Greengard P. Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons. Nature. 402:1999;669-671.
4. Dhavan R., Tsai L.H. A decade of CDK5. Nat Rev Mol Cell Biol. 2:2001;749-759.
5. Fletcher A.I., Shuang R., Giovannucci D.R., Zhang L., Bittner M.A., Stuenkel E.L. Regulation of exocytosis by cyclin-dependent kinase 5 via phosphorylation of Munc18. J Biol Chem. 274:1999;4027-4035.
6. Horger B.A., Iyasere C.A., Berhow M.T., Messer C.J., Nestler E.J., Taylor J.R. Enhancement of locomotor activity and conditioned reward to cocaine by brain-derived neurotrophic factor. J Neurosci. 19:1999;4110-4122.
7. Humbert S., Dhavan R., Tsai L. p39 activates cdk5 in neurons, and is associated with the actin cytoskeleton. J Cell Sci. 113:2000;975-983.
8. Kelz M.B., Chen J., Carlezon W.B. Jr, Whisler K., Gilden L., Beckmann A.M., Steffen C., Zhang Y.J., Marotti L., Self D.W. Expression of the transcription factor delta fos B in the brain controls sensitivity to cocaine. Nature. 401:1999;272-276.
9. Li B.S., Sun M.K., Zhang L., Takahashi S., Ma W., Vinade L., Kulkarni A.B., Brady R.O., Pant H.C. Regulation of NMDA receptors by cyclin-dependent kinase 5. Proc Natl Acad Sci USA. 98:2001;12742-12747.
10. Matsubara M., Kusubata M., Ishiguro K., Uchida T., Titani K., Taniguchi H. Site-specific phosphorylation of synapsin I by mitogen-activated protein kinase and Cdk5 and its effects on physiological functions. J Biol Chem. 271:1996;21108-21113.
11. Meredith G.E., Ypuma P., Zahm D.S. Effects of dopamine depletion on the morphology of medium spiny neurons in the shell and core of the rat nucleus accumbens. J Neurosci. 15:1995;3808-3820.
12. Nestler E.J. Molecular basis of long-term plasticity underlying drug addiction. Nat Rev Neurosci. 2:2001;119-128.
13. Nikolic M., Dudek H., Kwon Y.T., Ramos Y.F., Tsai L.H. The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation. Genes Dev. 10:1996;816-825.
14. Norrholm S.D., Ouimet C.C. Repeated fluoxetine administration prevents age-associated dendritic spine proliferation in juvenile rat hippocampus. Brain Res. 883:2000;205-215.
15. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates. 1986;Academic Press, Orlando, FL.
16. Punch L., Self D., Nestler E.J., Taylor J.R. Opposite modulation of opiate withdrawal behaviors upon microinfusion of a protein kinase A inhibitor versus activator into the locus coeruleus or periaquiductal gray. J Neurosci. 17:1997;8528-8535.
17. Robinson T.E., Gorny G., Mitton E., Kolb B. Cocaine self-administration alters the morphology of dendrites and dendritic spines in the nucleus accumbens and neocortex. Synapse. 39:2001;257-266.
18. Robinson T.E., Kolb B. Alterations in the morphology of dendrites and dendritic spines in the nucleus accumbens and prefrontal cortex following repeated treatment with amphetamine or cocaine. Eur J Pharmacol. 11:1999;1598-1604.
19. Segal M., Andersen P. Dendritic spines shaped by synaptic activity. Curr Opin Neurobiol. 10:2000;582-586.
20. Shuang R., Zhang L., Fletcher A., Groblewski G.E., Pevsner J., Steunkel E.L. Regulation of Munc-18/syntaxin 1A interaction by cyclin-dependent kinase 5 in nerve endings. J Biol Chem. 273:1998;4957-4966.
21. Smith D.S., Greer P.L., Tsai L.H. Cdk5 on the brain. Cell Growth Differ. 12:2001;277-283.