Construction and characterization of a kappa opioid receptor devoid of all free cysteines

Protein Engineering, Design and Selection

Volumn 17, Issue 1, 2004, Pages 37-48

  Ott, David ^a   Frischknecht, Renato ^a   Plückthun, Andreas ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Cysteine replacement; G protein coupled receptor; Membrane proteins; Protein design

Indexed keywords

CYSTEINE; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; KAPPA OPIATE RECEPTOR; NALOXONE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL GROWTH; CELL MEMBRANE; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; MAMMAL CELL; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; SEQUENCE HOMOLOGY; WILD TYPE;

ADENYLATE CYCLASE; AMINO ACIDS; ANIMALS; BLOTTING, WESTERN; CELL DIVISION; CELL LINE; CELL MEMBRANE; COS CELLS; CYSTEINE; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENETIC VECTORS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; IMMUNOHISTOCHEMISTRY; LIGANDS; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MODELS, MOLECULAR; MUTATION; NALOXONE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, OPIOID, KAPPA; TIME FACTORS; TRANSFECTION;

ANIMALIA; MAMMALIA;

EID: 0842313318     PISSN: 17410126     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/gzh004     Document Type: Article

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