Activation of the cloned human kappa opioid receptor by agonists enhances [35S]GTPγS binding to membranes: Determination of potencies and efficacies of ligands

Journal of Pharmacology and Experimental Therapeutics

Volumn 282, Issue 2, 1997, Pages 676-684

  Zhu, Jinmin ^a   Luo, Lai Yi ^a   Li, Jian Guo ^a   Chen, Chongguang ^a   Liu Chen, Lee Yuan ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZAMIDE; 3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE; BETA FUNALTREXAMINE; BUPRENORPHINE; DYNORPHIN A; ETHYLKETAZOCINE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE DIPHOSPHATE; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR AGONIST; LIGAND; MAGNESIUM ION; NALBUPHINE; NALORPHINE; NALOXONE; NORBINALTORPHIMINE; PENTAZOCINE; SODIUM ION; TIFLUADOM;

ANIMAL CELL; ARTICLE; BINDING KINETICS; DOSE RESPONSE; DRUG EFFICACY; DRUG POTENCY; DRUG RECEPTOR BINDING; HUMAN; LIGAND BINDING; MEMBRANE BINDING; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; STEREOSPECIFICITY;

3,4-DICHLORO-N-METHYL-N-(2-(1-PYRROLIDINYL)-CYCLOHEXYL)-BENZENEACETAMIDE, (TRANS)-ISOMER; ADENYLATE CYCLASE TOXIN; ANIMALS; BINDING SITES; CELL MEMBRANE; CHO CELLS; CHOLERA TOXIN; CLONING, MOLECULAR; CRICETINAE; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; ENKEPHALIN, D-PENICILLAMINE (2,5)-; ENKEPHALINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); GUANOSINE DIPHOSPHATE; HUMANS; KINETICS; MAGNESIUM; PERTUSSIS TOXIN; PYRROLIDINES; RECEPTORS, OPIOID, KAPPA; RECOMBINANT PROTEINS; SODIUM; SULFUR RADIOISOTOPES; VIRULENCE FACTORS, BORDETELLA;

EID: 0030818768     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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