Construction of a high affinity zinc switch in the κ-opioid receptor

Journal of Biological Chemistry

Volumn 271, Issue 14, 1996, Pages 7875-7878

  Thirstrup, Kenneth ^a   Ellingt, Christian E ^a   Hjorth, Siv A ^a   Schwartz, Thue W ^a,b  

^a Rigshospitalet   (Denmark)

^b INSTITUTE OF MOLECULAR BIOLOGY   (Armenia)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; COPPER CHLORIDE; DIPRENORPHINE; DYNORPHIN A; ENADOLINE; GUANINE NUCLEOTIDE BINDING PROTEIN; KAPPA OPIATE RECEPTOR; NALOXONE; NEUROKININ 1 RECEPTOR; NORBINALTORPHIMINE; TACHYKININ RECEPTOR; TRITIUM; ZINC; ZINC CHLORIDE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; BINDING SITE; DOSE RESPONSE; LIGAND BINDING; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING;

AMINO ACID SEQUENCE; ANIMALS; HISTIDINE; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, NEUROKININ-1; RECEPTORS, OPIOID, KAPPA; STRUCTURE-ACTIVITY RELATIONSHIP; ZINC;

ANIMALIA; TRITIUM;

EID: 0029873472     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.14.7875     Document Type: Article

References (37)

1. Schertler, G. F., Villa, C., and Henderson, R. (1993) Nature 362, 770-772
2. Unger, V. M., and Schertler, G. F. X. (1995) Biophys. J. 68, 1776-1786
3. Baldwin, J. M. (1993) EMBO J. 12, 1693-1703
4. Schwartz, T. W. (1994) Curr. Opin. Biotechnol. 5, 434-444
5. Suryanarayana, S., Daunt, D. A., Zastrow, M. V., and Kobilka, B. K. (1991) J. Biol. Chem. 266, 15488-15492
6. Gether, U., Yokota, Y., Emonds-Alt, X., Breliere, J.-C., Lowe, J. A., III, Snider, R. M., Nakanishi, S., and Schwartz, T. W. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 6194-6198
7. Strader, C. D., Gaffney, T., Sugg, E. E., Candelore, M. R., Keys, R., Patchett, A. A., and Dixon, R. A. F. (1991) J. Biol. Chem. 266, 5-8
8. Gether, U., Johansen, T. E., Snider, R. M., Lowe, J. A., III, Nakanishi, S., and Schwartz, T. W. (1993) Nature 362, 345-348
9. Elling, C. E., Nielsen, S. M., and Schwartz, T. W. (1995) Nature 374, 74-77
10. Ho, S. N., Hunt, H. D., Horton, R. M., Pullen, J. K., and Pease, L. R. (1989) Gene (Amst.) 77, 51-59
11. Johansen, T. E., Schøller, M. S., Tolstoy, S., and Schwartz, T. W. (1990) FEBS Lett. 267, 289-294
12. Gether, U., Johansen, T. E., and Schwartz, T. W. (1993) J. Biol. Chem. 268, 7893-7898
13. Henderson, R., Baldwin, J. M., Ceska, T. A., Zemlin, F., Beckmann, E., and Downing, K. H. (1990) J. Mol. Biol 213, 899-929
14. Chakrabarti, P. (1990) Protein Eng. 4, 57-63
15. Ippolito, J. A., and Christianson, D. W. (1994) Biochemistry 33, 15241-15249
16. Ponder, J. W., and Richards, F. M. (1987) J. Mol. Biol. 193, 775-792
17. Regan, L. (1993) Annu. Rev. Biophys. Biomol. Struct. 22, 257-281
18. Glusker, J. P. (1991) Adv. Protein Chem. 42, 1-76
19. Strader, C. D., Candelore, M., Hill, W. S., Sigal, I. S., and Dixon, R. A. F. (1989) J. Biol. Chem. 264, 13572-13578
20. Higaki, J. N., Fletterick, R. J., and Craik, C. S. (1992) Trends Biochem. Sci. 17, 100-104
21. Regan, L. (1995) Trends Biochem. Sci. 17, 280-285
22. Regan, L., and Clarke, N. D. (1990) Biochemistry 29, 10878-10883
23. Pessi, A., Bianchi, E., Crameri, A., Venturini, S., Tramontane, A., and Sollazzo, M. (1993) Nature 362, 367-369
24. McGrath, M. E., Haymore, B. L., Summers, N. L., Craik, C. S., and Fletterick, R. J. (1993) Biochemistry 32, 1914-1919
25. Iverson, B. L., Iverson, S. A., Roberts, V. A., Getzoff, E. D., Tainer, J. A., Benkovic, S. J., and Lerner, R. A. (1990) Science 249, 659-662
26. Roberts, V. A., Iverson, B. L., Iverson, S. A., Benkovic, S. J., Lerner, R. A., Getzoff, E. D., and Tainer, J. A. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 6654-6658
27. Jung, K., Voss, J., He, M., Hubbell, W. L., and Kaback, R. H. (1995) Biochemistry 34, 6272-6277
28. Gether, U., Nilsson, L., Lowe, J. A., III, and Schwartz, T. W. (1994) J. Biol. Chem. 269, 23959-23964
29. Fong, T. M., Cascieri, M. A., Yu, H., Bansal, A., Swain, C., and Strader, C. D. (1993) Nature 362, 350-353
30. Yu, H., Kono, M., Mckee, T. D., and Oprian, D. D. (1995) Biochemistry 46, 14963-14969
31. Zoffmann, S., Gether, U., and Schwartz, T. W. (1993) FEBS Lett. 336, 506-510
32. Schwartz, T. W., Gether, U., Schambye, H. T., and Hjorth, S. A. (1995) Curr. Pharm. Design. 1, 355-371
33. Wang, J. B., Johnson, P. S., Wu, M. J., Wang, W. F., and Uhl, G. R. (1994) J. Biol. Chem. 269, 25966-25969
34. Xue, J., Chen, C., Zhu, J., Kunapuli, S., DeRiel, J. K., Yu, L., and Lie-Chen, L. (1994) J. Biol. Chem. 269, 30195-30199
35. Hjorth, S. A., Thirstrup, K., Grandy, D. K., and Schwartz, T. W. (1995) Mol. Pharmacol. 47, 1089-1094
36. Meng, F., Hoversten, M. T., Thompson, R. C., Taylor, L., Watson, S. J., and Akil, H. (1995) J. Biol. Chem. 270, 12730-12736
37. Huang, R. C., Yu, H., Strader, C. D., and Fong, T. M. (1994) Biochemistry 33, 3007-3013