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Volumn 270, Issue 18, 2003, Pages 3829-3838

Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase

Author keywords

Adipocyte; GSK 3; Insulin; Muscle; P38 MAP kinase

Indexed keywords

2 (3 CHLORO 4 HYDROXYANILINO) 3 (2 NITROPHENYL)MALEIMIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ENZYME INHIBITOR; GLUCOSE; GLYCOGEN SYNTHASE; GLYCOGEN SYNTHASE KINASE 3; LITHIUM; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 0141558915     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2003.03777.x     Document Type: Article
Times cited : (62)

References (42)
  • 1
    • 0034792872 scopus 로고    scopus 로고
    • Intracellular signalling mechanisms regulating glucose transport in insulin-sensitive tissues
    • Litherland, G.J., Hajduch, E. & Hundal, H.S. (2001) Intracellular signalling mechanisms regulating glucose transport in insulin-sensitive tissues. Mol. Memb. Biol. 18, 195-204.
    • (2001) Mol. Memb. Biol. , vol.18 , pp. 195-204
    • Litherland, G.J.1    Hajduch, E.2    Hundal, H.S.3
  • 2
    • 0028085078 scopus 로고
    • The insulin signaling system
    • White, M.F. & Kahn, C.R. (1994) The insulin signaling system. J. Biol. Chem. 269, 1-4.
    • (1994) J. Biol. Chem. , vol.269 , pp. 1-4
    • White, M.F.1    Kahn, C.R.2
  • 3
    • 0028032895 scopus 로고
    • Alternative pathway of insulin signaling in mice with targeted disruption of the IRS-1 gene
    • Araki, E., Lipes, M.A., Patti, M.E., Bruning, J.C., Haag, B., Johnson, R.S. & Kahn, C.R. (1994) Alternative pathway of insulin signaling in mice with targeted disruption of the IRS-1 gene. Nature 372, 186-190.
    • (1994) Nature , vol.372 , pp. 186-190
    • Araki, E.1    Lipes, M.A.2    Patti, M.E.3    Bruning, J.C.4    Haag, B.5    Johnson, R.S.6    Kahn, C.R.7
  • 4
    • 0030858852 scopus 로고    scopus 로고
    • Phorbol esters stimulate muscle glucose transport by a mechanism distinct from the insulin and hypoxia pathways
    • Hansen, P.A., Corbett, J.A. & Holloszy, J.O. (1997) Phorbol esters stimulate muscle glucose transport by a mechanism distinct from the insulin and hypoxia pathways. Am. J. Physiol. 36, E28-E36.
    • (1997) Am. J. Physiol. , vol.36
    • Hansen, P.A.1    Corbett, J.A.2    Holloszy, J.O.3
  • 6
    • 0028308412 scopus 로고
    • Phosphatylinositol 3-kinase activation is required for insulin stimulation off pp70, s6 kinase, DNA synthesis, and glucose transporter translocation
    • Cheatham, B., Vlahos, C.J., Cheatham, L., Wang, L., Blenis, J. & Kahn, C.R. (1994) Phosphatylinositol 3-kinase activation is required for insulin stimulation off pp70, s6 kinase, DNA synthesis, and glucose transporter translocation. Mol. Cell Biol. 14, 4902-4911.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 4902-4911
    • Cheatham, B.1    Vlahos, C.J.2    Cheatham, L.3    Wang, L.4    Blenis, J.5    Kahn, C.R.6
  • 7
    • 0029122720 scopus 로고
    • Multiple roles of phosphatidylinositol 3-kinase in regulation of glucose-transport, amino-acid-transport, and glucose transporters in L6 skeletal-muscle cells
    • Tsakiridis, T., McDowell, H.E., Walker, T., Downes, C.P., Hundal, H.S., Vranic, M. & Klip, A. (1995) Multiple roles of phosphatidylinositol 3-kinase in regulation of glucose-transport, amino-acid-transport, and glucose transporters in L6 skeletal-muscle cells. Endocrinology 136, 4315-4322.
    • (1995) Endocrinology , vol.136 , pp. 4315-4322
    • Tsakiridis, T.1    McDowell, H.E.2    Walker, T.3    Downes, C.P.4    Hundal, H.S.5    Vranic, M.6    Klip, A.7
  • 9
    • 0030059569 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase acts at an intracellular membrane site to enhance GLUT4 exocytosis in 3T3-L1 cells
    • Yang, J., Clarke, J.F., Ester, C.J., Young, P.W., Kasuga, M. & Holman, G.D. (1996) Phosphatidylinositol 3-kinase acts at an intracellular membrane site to enhance GLUT4 exocytosis in 3T3-L1 cells. Biochem. J. 313, 125-131.
    • (1996) Biochem. J. , vol.313 , pp. 125-131
    • Yang, J.1    Clarke, J.F.2    Ester, C.J.3    Young, P.W.4    Kasuga, M.5    Holman, G.D.6
  • 10
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin-mediated protein kinase B
    • Cross, D.A.E., Alessi, D.R., Cohen, P., Andjelkovic, M. & Hemmings, B.A. (1995) Inhibition of glycogen synthase kinase-3 by insulin-mediated protein kinase B. Nature 378, 785-789.
    • (1995) Nature , vol.378 , pp. 785-789
    • Cross, D.A.E.1    Alessi, D.R.2    Cohen, P.3    Andjelkovic, M.4    Hemmings, B.A.5
  • 12
    • 0031127305 scopus 로고    scopus 로고
    • Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα
    • Alessi, D.R., James, S.R., Downes, C.P., Holmes, A.B., Gaffney, P.R.J., Reese, C.B. & Cohen, P. (1997) Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα. Curr. Biol. 7, 261-269.
    • (1997) Curr. Biol. , vol.7 , pp. 261-269
    • Alessi, D.R.1    James, S.R.2    Downes, C.P.3    Holmes, A.B.4    Gaffney, P.R.J.5    Reese, C.B.6    Cohen, P.7
  • 14
    • 0030841793 scopus 로고    scopus 로고
    • The tenth datta lecture - PDK1, one of the missing links in insulin signal transduction?
    • Cohen, P., Alessi, D.R. & Cross, D.A.E. (1997) The tenth datta lecture - PDK1, one of the missing links in insulin signal transduction? FEBS Lett. 410, 3-10.
    • (1997) FEBS Lett. , vol.410 , pp. 3-10
    • Cohen, P.1    Alessi, D.R.2    Cross, D.A.E.3
  • 15
    • 0035896366 scopus 로고    scopus 로고
    • Protein kinase B: A key regulator of glucose transport?
    • Hajduch, E., Litherland, G.J. & Hundal, H.S. (2001) Protein kinase B: a key regulator of glucose transport? FEBS Lett. 492, 199-203.
    • (2001) FEBS Lett. , vol.492 , pp. 199-203
    • Hajduch, E.1    Litherland, G.J.2    Hundal, H.S.3
  • 16
    • 0030984321 scopus 로고    scopus 로고
    • New insights into the role and mechanism of glycogen synthase activation by insulin
    • Lawrence, J.C. & Roach, P.J. (1997) New insights into the role and mechanism of glycogen synthase activation by insulin. Diabetes 46, 541-547.
    • (1997) Diabetes , vol.46 , pp. 541-547
    • Lawrence, J.C.1    Roach, P.J.2
  • 17
    • 0020585165 scopus 로고
    • Glycogen synthase from rabbit skeletal muscle - Effects of insulin on the state of phosphorylation of the 7 phosphoserine residues in vivo
    • Parker, P.J., Caudwell, F.B. & Cohen, P. (1983) Glycogen synthase from rabbit skeletal muscle - effects of insulin on the state of phosphorylation of the 7 phosphoserine residues in vivo. Eur. J. Biochem. 130, 227-243.
    • (1983) Eur. J. Biochem. , vol.130 , pp. 227-243
    • Parker, P.J.1    Caudwell, F.B.2    Cohen, P.3
  • 18
    • 0021039875 scopus 로고
    • 'Insulin-like' effects of lithium ion on isolated rat adipocytes. I. Stimulation of glycogenesis beyond glucose transport
    • Cheng, K., Creacy, S. & Larner, J. (1983) 'Insulin-like' effects of lithium ion on isolated rat adipocytes. I. Stimulation of glycogenesis beyond glucose transport. Mol. Cell Biochem. 56, 177-182.
    • (1983) Mol. Cell Biochem. , vol.56 , pp. 177-182
    • Cheng, K.1    Creacy, S.2    Larner, J.3
  • 19
    • 0031869859 scopus 로고    scopus 로고
    • Stimulatory effect of lithium on glucose transport in rat adipocytes is not mediated by elevation of IP1
    • Chen, X., McMahon, E.G. & Gulve, E.A. (1998) Stimulatory effect of lithium on glucose transport in rat adipocytes is not mediated by elevation of IP1. Am. J. Physiol. 275, E272-E277.
    • (1998) Am. J. Physiol. , vol.275
    • Chen, X.1    McMahon, E.G.2    Gulve, E.A.3
  • 20
    • 0028233347 scopus 로고
    • Lithium increases susceptibility of muscle glucose transport to stimulation by various agents
    • Tabata, I., Schluter, J., Gulve, E.A. & Holloszy, J.O. (1994) Lithium increases susceptibility of muscle glucose transport to stimulation by various agents. Diabetes 43, 903-907.
    • (1994) Diabetes , vol.43 , pp. 903-907
    • Tabata, I.1    Schluter, J.2    Gulve, E.A.3    Holloszy, J.O.4
  • 21
    • 0034717141 scopus 로고    scopus 로고
    • Inhibition of glycogen-synthase kinase 3 stimulates glycogen synthase and glucose transport by distinct mechanisms in 3T3-L1 adipocytes
    • Orena, S.J., Torchia, A.J. & Garofalo, R.S. (2000) Inhibition of glycogen-synthase kinase 3 stimulates glycogen synthase and glucose transport by distinct mechanisms in 3T3-L1 adipocytes. J. Biol. Chem. 275, 15765-15772.
    • (2000) J. Biol. Chem. , vol.275 , pp. 15765-15772
    • Orena, S.J.1    Torchia, A.J.2    Garofalo, R.S.3
  • 23
    • 0034797512 scopus 로고    scopus 로고
    • The role of protein phosphorylation in human health and disease. The Sir Hans Krebs Medal Lecture
    • Cohen, P. (2001) The role of protein phosphorylation in human health and disease. The Sir Hans Krebs Medal Lecture. Eur. J. Biochem. 268, 5001-5010.
    • (2001) Eur. J. Biochem. , vol.268 , pp. 5001-5010
    • Cohen, P.1
  • 24
    • 0026673857 scopus 로고
    • Lithium inhibits hepatic gluconeogenesis and phosphoenolpyruvate carboxykinase gene expression
    • Bosch, F., Rodriguez-Gil, J.E., Hatzoglou, M., Gomez-Foix, A.M. & Hanson, R.W. (1992) Lithium inhibits hepatic gluconeogenesis and phosphoenolpyruvate carboxykinase gene expression. J. Biol. Chem. 267, 2888-2893.
    • (1992) J. Biol. Chem. , vol.267 , pp. 2888-2893
    • Bosch, F.1    Rodriguez-Gil, J.E.2    Hatzoglou, M.3    Gomez-Foix, A.M.4    Hanson, R.W.5
  • 26
    • 0032486258 scopus 로고    scopus 로고
    • The activation of glycogen synthase by insulin switches from kinase inhibition to phosphatase activation during adipogenesis in 3T3-L1 cells
    • Brady, M.J., Bourbonais, F.J. & Saltiel, A.R. (1998) The activation of glycogen synthase by insulin switches from kinase inhibition to phosphatase activation during adipogenesis in 3T3-L1 cells. J. Biol. Chem. 273, 14063-14066.
    • (1998) J. Biol. Chem. , vol.273 , pp. 14063-14066
    • Brady, M.J.1    Bourbonais, F.J.2    Saltiel, A.R.3
  • 28
    • 0031782480 scopus 로고    scopus 로고
    • Constitutive activation of protein kinase Bα (PKBα) by membrane targeting promotes glucose and System A amino acid transport, protein synthesis and GSK3 inactivation in L6 muscle cells
    • Hajduch, E., Alessi, D.R., Hemmings, B.A. & Hundal, H.S. (1998) Constitutive activation of protein kinase Bα (PKBα) by membrane targeting promotes glucose and System A amino acid transport, protein synthesis and GSK3 inactivation in L6 muscle cells. Diabetes 47, 1006-1013.
    • (1998) Diabetes , vol.47 , pp. 1006-1013
    • Hajduch, E.1    Alessi, D.R.2    Hemmings, B.A.3    Hundal, H.S.4
  • 29
    • 0021997899 scopus 로고
    • Evidence for the involvement of vicinal sulfhydryl groups in insulin- activated hexose transport by 3T3-L1 adipocytes
    • Frost, S.C. & Lane, M.D. (1985) Evidence for the involvement of vicinal sulfhydryl groups in insulin- activated hexose transport by 3T3-L1 adipocytes. J. Biol. Chem. 260, 2646-2652.
    • (1985) J. Biol. Chem. , vol.260 , pp. 2646-2652
    • Frost, S.C.1    Lane, M.D.2
  • 30
    • 0016693548 scopus 로고
    • An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion
    • Green, H. & Kehinde, O. (1975) An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion. Cell 5, 19-27.
    • (1975) Cell , vol.5 , pp. 19-27
    • Green, H.1    Kehinde, O.2
  • 31
    • 0033579515 scopus 로고    scopus 로고
    • Regulation of glucose transport and glycogen synthesis in L6 muscle cells during oxidative stress: Evidence for cross-talk between the insulin and SAPK2/p38 MAP kinase signalling pathways
    • Blair, A.S., Hajduch, E., Litherland, G.J. & Hundal, H.S. (1999) Regulation of glucose transport and glycogen synthesis in L6 muscle cells during oxidative stress: Evidence for cross-talk between the insulin and SAPK2/p38 MAP kinase signalling pathways. J. Biol. Chem. 274, 36293-36299.
    • (1999) J. Biol. Chem. , vol.274 , pp. 36293-36299
    • Blair, A.S.1    Hajduch, E.2    Litherland, G.J.3    Hundal, H.S.4
  • 32
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantifies of protein utilizing the principle of protein-dye binding
    • Bradford, M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantifies of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 33
    • 0027978816 scopus 로고
    • The inhibition of glycogen synthase kinase-3 by insulin or IGF-1 in the rat skeletal muscle cell line L6 by wortmannin, but not rapamycin: Evidence that wortmannin blocks activation of the MAP kinase pathway in L6 cells between Ras and Raf
    • Cross, D.A.E., Alessi, D.R., Vandenheede, J.R., McDowell, H.E., Hundal, H.S. & Cohen, P. (1994) The inhibition of glycogen synthase kinase-3 by insulin or IGF-1 in the rat skeletal muscle cell line L6 by wortmannin, but not rapamycin: evidence that wortmannin blocks activation of the MAP kinase pathway in L6 cells between Ras and Raf. Biochem. J. 303, 21-26.
    • (1994) Biochem. J. , vol.303 , pp. 21-26
    • Cross, D.A.E.1    Alessi, D.R.2    Vandenheede, J.R.3    McDowell, H.E.4    Hundal, H.S.5    Cohen, P.6
  • 34
    • 0034805180 scopus 로고    scopus 로고
    • Lithium inhibits glycogen synthase kinase-3 by competition for magnesium
    • Ryves, W.J. & Harwood, A.J. (2001) Lithium inhibits glycogen synthase kinase-3 by competition for magnesium. Biochem. Biophys. Res. Commun. 280, 720-725.
    • (2001) Biochem. Biophys. Res. Commun. , vol.280 , pp. 720-725
    • Ryves, W.J.1    Harwood, A.J.2
  • 35
    • 0034845958 scopus 로고    scopus 로고
    • PKB/Akt: A key mediator of cell proliferation, survival and insulin responses?
    • Lawlor, M.A. & Alessi, D.R. (2001) PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? J. Cel. Sci. 114, 2903-2910.
    • (2001) J. Cel. Sci. , vol.114 , pp. 2903-2910
    • Lawlor, M.A.1    Alessi, D.R.2
  • 36
    • 0034283186 scopus 로고    scopus 로고
    • L-Leucine availability regulates phosphatidylinositol 3-kinase, p70, S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: Evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the L-leucine-induced up-regulation of System A amino acid transport
    • Peyrollier, K., Hajduch, E., Blair, A.S., Hyde, R. & Hundal, H.S. (2000) L-Leucine availability regulates phosphatidylinositol 3-kinase, p70, S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the L-leucine-induced up-regulation of System A amino acid transport. Biochem. J. 350, 361-368.
    • (2000) Biochem. J. , vol.350 , pp. 361-368
    • Peyrollier, K.1    Hajduch, E.2    Blair, A.S.3    Hyde, R.4    Hundal, H.S.5
  • 37
    • 0035846952 scopus 로고    scopus 로고
    • Regulation of glycogen synthesis by amino acids in cultured human muscle cells
    • Armstrong, J.L., Bonavaud, S.M., Toole, B.J. & Yezman, S.J. (2001) Regulation of glycogen synthesis by amino acids in cultured human muscle cells. J. Biol. Chem. 276, 952-956.
    • (2001) J. Biol. Chem. , vol.276 , pp. 952-956
    • Armstrong, J.L.1    Bonavaud, S.M.2    Toole, B.J.3    Yezman, S.J.4
  • 38
    • 0036302960 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase 3 improves insulin action and glucose metabolism in human skeletal muscle
    • Nikoulina, S.E., Ciaraldi, T.P., Mudaliar, S., Carter, L., Johnson, K. & Henry, R.R. (2002) Inhibition of glycogen synthase kinase 3 improves insulin action and glucose metabolism in human skeletal muscle. Diabetes 51, 2190-2198.
    • (2002) Diabetes , vol.51 , pp. 2190-2198
    • Nikoulina, S.E.1    Ciaraldi, T.P.2    Mudaliar, S.3    Carter, L.4    Johnson, K.5    Henry, R.R.6
  • 40
    • 0030931560 scopus 로고    scopus 로고
    • Phosphorylation of insulin receptor substrate 1 by glycogen synthase kinase 3 impairs insulin action
    • Eldar-Finkelman, H. & Krebs, E.G. (1997) Phosphorylation of insulin receptor substrate 1 by glycogen synthase kinase 3 impairs insulin action. Proc. Natl Acad. Sci. USA 94, 9660-9664.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 9660-9664
    • Eldar-Finkelman, H.1    Krebs, E.G.2
  • 42
    • 0037040903 scopus 로고    scopus 로고
    • Lithium induces NF-kappa B activation and interleukin-8 production in human intestinal epithelial cells
    • Nemeth, Z.H., Deitch, E.A., Szabo, C., Fekete, Z., Hauser, C.J. & Hasko, G. (2002) Lithium induces NF-kappa B activation and interleukin-8 production in human intestinal epithelial cells. J. Biol. Chem. 277, 7713-7719.
    • (2002) J. Biol. Chem. , vol.277 , pp. 7713-7719
    • Nemeth, Z.H.1    Deitch, E.A.2    Szabo, C.3    Fekete, Z.4    Hauser, C.J.5    Hasko, G.6


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