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Volumn 8, Issue 2, 2003, Pages 297-321

Ketolides: An emerging treatment for macrolide-resistant respiratory infections, focusing on S. pneumoniae

Author keywords

Cethromycin (ABT 773); Ketolides; Macrolide resistance; Telithromycin

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; AZITHROMYCIN; BETA LACTAM ANTIBIOTIC; CARBAMAZEPINE; CEFUROXIME; CEFUROXIME AXETIL; CETHROMYCIN; CLARITHROMYCIN; DIGOXIN; ERYTHROMYCIN; HMR 3562; HMR 3787; ITRACONAZOLE; JNJ 17155437; JNJ 17155528; KETOCONAZOLE; KETOLIDE; LEVOFLOXACIN; MACROLIDE; PENICILLIN G; PENICILLIN V; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RANITIDINE; SUCRALFATE; TE 802; TELITHROMYCIN; THEOPHYLLINE DERIVATIVE; TROVAFLOXACIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; WARFARIN;

EID: 0346367066     PISSN: 14728214     EISSN: None     Source Type: Journal    
DOI: 10.1517/14728214.8.2.297     Document Type: Review
Times cited : (29)

References (184)
  • 1
    • 0036732810 scopus 로고    scopus 로고
    • Clinical and economic implications of antimicrobial resistance for the management of community-acquired respiratory tract infections
    • NICOLAU DP: Clinical and economic implications of antimicrobial resistance for the management of community-acquired respiratory tract infections. J. Antimicrob. Chemother. (2002) 50:61-70.
    • (2002) J. Antimicrob. Chemother. , vol.50 , pp. 61-70
    • Nicolau, D.P.1
  • 2
    • 0035059952 scopus 로고    scopus 로고
    • Review of macrolides and ketolides: Focus on respiratory tract infections
    • ZHANEL GG, DUECK M, HOBAN DJ et al.: Review of macrolides and ketolides: focus on respiratory tract infections. Drugs (2001) 61:443-498.
    • (2001) Drugs , vol.61 , pp. 443-498
    • Zhanel, G.G.1    Dueck, M.2    Hoban, D.J.3
  • 3
    • 0037334850 scopus 로고    scopus 로고
    • Structural basis for the antibiotic activity of ketolides and azalides
    • SCHLUNZEN F, HARMS JM, FRANCESCHI F et al.: Structural basis for the antibiotic activity of ketolides and azalides. Structure (Camb.) (2003) 11:329-338.
    • (2003) Structure (Camb.) , vol.11 , pp. 329-338
    • Schlunzen, F.1    Harms, J.M.2    Franceschi, F.3
  • 4
    • 0037248162 scopus 로고    scopus 로고
    • International guidelines for the treatment of community-acquired pneumonia in adults: The role of macrolides
    • FILE TM JR, TAN JS: International guidelines for the treatment of community-acquired pneumonia in adults: the role of macrolides. Drugs (2003) 63:181-205.
    • (2003) Drugs , vol.63 , pp. 181-205
    • File Jr., T.M.1    Tan, J.S.2
  • 5
    • 0029797383 scopus 로고    scopus 로고
    • Erythromycin, clarithromycin and azithromycin: Are the differences real?
    • discussion 55
    • AMSDEN GW: Erythromycin, clarithromycin and azithromycin: are the differences real? Clin. Ther. (1996) 18:56-72; discussion 55.
    • (1996) Clin. Ther. , vol.18 , pp. 56-72
    • Amsden, G.W.1
  • 7
    • 0034085604 scopus 로고    scopus 로고
    • Highlights of semisynthetic developments from erythromycin A
    • WU YJ: Highlights of semisynthetic developments from erythromycin A. Curr. Pharm. Des. (2000) 6:181-223.
    • (2000) Curr. Pharm. Des. , vol.6 , pp. 181-223
    • Wu, Y.J.1
  • 8
    • 0026527863 scopus 로고
    • Clarithromycin and azithromycin: New macrolide antibiotics
    • PISCITELLI SC, DANZIGER LH, RODVOLD FA: Clarithromycin and azithromycin: new macrolide antibiotics. Clin. Pharm. (1992) 11:137-152.
    • (1992) Clin. Pharm. , vol.11 , pp. 137-152
    • Piscitelli, S.C.1    Danziger, L.H.2    Rodvold, F.A.3
  • 10
    • 0024597808 scopus 로고
    • Comparative pharmacokinetics of clarithromycin (TE-031), a new macrolide antibiotic and erythromycin in rats
    • KOHNO Y, YOSHIDA H, SUWA T, SUGA T: Comparative pharmacokinetics of clarithromycin (TE-031), a new macrolide antibiotic and erythromycin in rats. Antimicrob. Agents Chemother. (1989) 33:751-756.
    • (1989) Antimicrob. Agents Chemother. , vol.33 , pp. 751-756
    • Kohno, Y.1    Yoshida, H.2    Suwa, T.3    Suga, T.4
  • 11
    • 0024428724 scopus 로고
    • Effects of clarithromycin on cytochrome P450. Comparison with other macrolides
    • TINEL M, DESCATOIRE V, LARREY D et al.: Effects of clarithromycin on cytochrome P450. Comparison with other macrolides. J. Pharmacol. Exp. Ther. (1989) 250:746-751.
    • (1989) J. Pharmacol. Exp. Ther. , vol.250 , pp. 746-751
    • Tinel, M.1    Descatoire, V.2    Larrey, D.3
  • 12
    • 0029130840 scopus 로고
    • Macrolide antibacterials. Drug interactions of clinical significance
    • VON ROSENSTEIL NA, ADAM D: Macrolide antibacterials. Drug interactions of clinical significance. Drug Saf. (1995) 13:105-122.
    • (1995) Drug Saf. , vol.13 , pp. 105-122
    • Von Rosensteil, N.A.1    Adam, D.2
  • 13
    • 0002078065 scopus 로고    scopus 로고
    • Advanced-generation macrolides: Tissue-directed antibiotics
    • AMSDEN GW: Advanced-generation macrolides: tissue-directed antibiotics. Int. J. Antimicrob. Agents (2001) 18(Suppl. 1):S11-S15.
    • (2001) Int. J. Antimicrob. Agents , vol.18 , Issue.SUPPL. 1
    • Amsden, G.W.1
  • 14
    • 0034999522 scopus 로고    scopus 로고
    • Antimicrobial resistance among clinical isolates of Streptococcus pneumoniae in the United States during 1999-2000, including a comparison of resistance rates since 1994-1995
    • DOERN GV, HEILMANN KP, HUYNH HK, RHOMBERG PR, COFFMAN SL, BRUEGGEMANN AB: Antimicrobial resistance among clinical isolates of Streptococcus pneumoniae in the United States during 1999-2000, including a comparison of resistance rates since 1994-1995. Antimicrob. Agents Chemother. (2001) 45:1721-1729.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 1721-1729
    • Doern, G.V.1    Heilmann, K.P.2    Huynh, H.K.3    Rhomberg, P.R.4    Coffman, S.L.5    Brueggemann, A.B.6
  • 15
    • 0036732849 scopus 로고    scopus 로고
    • Increasing prevalence of antimicrobial resistance among isolates of Streptococcus pneumoniae from the PROTEKT surveillance study and comparative in vitro activity of the ketolide, telithromycin
    • FELMINGHAM D, REINERT RR, HIRAKATA Y, RODLOFF A: Increasing prevalence of antimicrobial resistance among isolates of Streptococcus pneumoniae from the PROTEKT surveillance study and comparative in vitro activity of the ketolide, telithromycin. J. Antimicrob. Chemother. (2002) 50(Suppl. 51):25-37.
    • (2002) J. Antimicrob. Chemother. , vol.50 , Issue.SUPPL. 51 , pp. 25-37
    • Felmingham, D.1    Reinert, R.R.2    Hirakata, Y.3    Rodloff, A.4
  • 16
    • 0038441345 scopus 로고    scopus 로고
    • Antimicrobial resistance in respiratory tract Streptococcus pneumoniae isolates: Results of the Canadian Respiratory Organism Susceptibility Study, 1997 to 2002
    • ZHANEL GG, PALATNICK L, NICHOL KA, BELLYOU T, LOW DE, HOBAN DJ: Antimicrobial resistance in respiratory tract Streptococcus pneumoniae isolates: results of the Canadian Respiratory Organism Susceptibility Study, 1997 to 2002. Antimicrob. Agents Chemother. (2003) 47:1867-1874.
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 1867-1874
    • Zhanel, G.G.1    Palatnick, L.2    Nichol, K.A.3    Bellyou, T.4    Low, D.E.5    Hoban, D.J.6
  • 17
    • 0035723421 scopus 로고    scopus 로고
    • Relative potency of telithromycin, azithromycin and erythromycin against recent clinical isolates of Gram-positive cocci
    • BARRY AL, FUCHS PC, BROWN SD: Relative potency of telithromycin, azithromycin and erythromycin against recent clinical isolates of Gram-positive cocci. Eur. J. Clin. Microbiol. Infect. Dis. (2001) 20:494-497.
    • (2001) Eur. J. Clin. Microbiol. Infect. Dis. , vol.20 , pp. 494-497
    • Barry, A.L.1    Fuchs, P.C.2    Brown, S.D.3
  • 19
    • 0037226399 scopus 로고    scopus 로고
    • In vitro activities of cethromycin (ABT-773), a new ketolide, against Streptococcus pneumoniae strains that are not susceptible to penicillin or macrolides
    • MASON EO JR, LAMBERTH LB, WALD ER, BRADLEY JS, BARSON WJ, KAPLAN SL: In vitro activities of cethromycin (ABT-773), a new ketolide, against Streptococcus pneumoniae strains that are not susceptible to penicillin or macrolides. Antimicrob. Agents Chemother. (2003) 47:166-169.
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 166-169
    • Mason Jr., E.O.1    Lamberth, L.B.2    Wald, E.R.3    Bradley, J.S.4    Barson, W.J.5    Kaplan, S.L.6
  • 20
    • 0034531935 scopus 로고    scopus 로고
    • Patterns of phenotypic resistance to the macrolide-lincosamide-ketolide-streptogramin group of antibiotics in staphylococci
    • HAMILTON-MILLER JM, SHAH S: Patterns of phenotypic resistance to the macrolide-lincosamide-ketolide-streptogramin group of antibiotics in staphylococci. J. Antimicrob. Chemother. (2000) 46:941-949.
    • (2000) J. Antimicrob. Chemother. , vol.46 , pp. 941-949
    • Hamilton-Miller, J.M.1    Shah, S.2
  • 21
    • 0031968046 scopus 로고    scopus 로고
    • Antipneumococcal activities of a ketolide (HMR 3647), a streptogramin (quinupristin-dalfopristin), a macrolide (erythromycin) and a lincosamide (clindamycin)
    • BARRY AL, FUCHS PC, BROWN SD: Antipneumococcal activities of a ketolide (HMR 3647), a streptogramin (quinupristin-dalfopristin), a macrolide (erythromycin) and a lincosamide (clindamycin). Antimicrob. Agents Chemother. (1998) 42:945-946.
    • (1998) Antimicrob. Agents Chemother. , vol.42 , pp. 945-946
    • Barry, A.L.1    Fuchs, P.C.2    Brown, S.D.3
  • 22
    • 0035112110 scopus 로고    scopus 로고
    • In vitro activities of the novel ketolide telithromycin (HMR 3647) against erythromycin-resistant Streptococcus species
    • JALAVA J, KATAJA J, SEPPALA H, HUOVINEN P: In vitro activities of the novel ketolide telithromycin (HMR 3647) against erythromycin-resistant Streptococcus species. Antimicrob. Agents Chemother. (2001) 45:789-793.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 789-793
    • Jalava, J.1    Kataja, J.2    Seppala, H.3    Huovinen, P.4
  • 23
    • 0036265885 scopus 로고    scopus 로고
    • Evolving resistance patterns in community-acquired respiratory tract pathogens: First results from the PROTEKT global surveillance study. Prospective Resistant Organism Tracking and Epidemiology for the Ketolide Telithromycin
    • FELMINGHAM D: Evolving resistance patterns in community-acquired respiratory tract pathogens: first results from the PROTEKT global surveillance study. Prospective Resistant Organism Tracking and Epidemiology for the Ketolide Telithromycin. J. Infect. (2002) 44(Suppl. A):3-10.
    • (2002) J. Infect. , vol.44 , Issue.SUPPL. A , pp. 3-10
    • Felmingham, D.1
  • 24
    • 0031942622 scopus 로고    scopus 로고
    • Susceptibilities of penicillin- and erythromycin-susceptible and -resistant pneumococci to HMR 3647 (RU 66647), a new kerolide, compared with susceptibilities to 17 other agents
    • PANKUCH GA, VISALLI MA, JACOBS MR, APPELBAUM PC: Susceptibilities of penicillin- and erythromycin-susceptible and -resistant pneumococci to HMR 3647 (RU 66647), a new kerolide, compared with susceptibilities to 17 other agents. Antimicrob. Agents Chemother. (1998) 42:624-630.
    • (1998) Antimicrob. Agents Chemother. , vol.42 , pp. 624-630
    • Pankuch, G.A.1    Visalli, M.A.2    Jacobs, M.R.3    Appelbaum, P.C.4
  • 25
    • 0036146498 scopus 로고    scopus 로고
    • Susceptibilities to telithromycin and six other agents and prevalence of macrolide resistance due to L4 ribosomal protein mutation among 992 Pneumococci from 10 central and Eastern European countries
    • NAGAI K, APPELBAUM PC, DAVIES TA et al.: Susceptibilities to telithromycin and six other agents and prevalence of macrolide resistance due to L4 ribosomal protein mutation among 992 Pneumococci from 10 central and Eastern European countries. Antimicrob. Agents Chemother. (2002) 46:371-377.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 371-377
    • Nagai, K.1    Appelbaum, P.C.2    Davies, T.A.3
  • 26
    • 0036171320 scopus 로고    scopus 로고
    • Comparison of in vitro activities of ABT-773 and telithromycin against macrolide-susceptible and -resistant streptococci and staphylococci
    • SHORTRIDGE VD, ZHONG P, CAO Z et al.: Comparison of in vitro activities of ABT-773 and telithromycin against macrolide-susceptible and -resistant streptococci and staphylococci. Antimicrob. Agents Chemother. (2002) 46:783-786.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 783-786
    • Shortridge, V.D.1    Zhong, P.2    Cao, Z.3
  • 27
    • 0035996126 scopus 로고    scopus 로고
    • In vitro activities of the ketolides ABT-773 and telithromycin and of three macrolides against genetically characterized isolates of Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae and Moraxella catarrhalis
    • SCHMITZ FJ, SCHWARZ S, MILATOVIC D, VERHOEF J, FLUIT AC: In vitro activities of the ketolides ABT-773 and telithromycin and of three macrolides against genetically characterized isolates of Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae and Moraxella catarrhalis. J. Antimicrob. Chemother. (2002) 50:145-148.
    • (2002) J. Antimicrob. Chemother. , vol.50 , pp. 145-148
    • Schmitz, F.J.1    Schwarz, S.2    Milatovic, D.3    Verhoef, J.4    Fluit, A.C.5
  • 28
    • 0033198896 scopus 로고    scopus 로고
    • In vitro activity of the novel ketolide HMR 3647 and comparative oral antibiotics against Canadian respiratory tract isolates of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis
    • HOBAN DJ, ZHANEL GG, KARLOWSKY JA: In vitro activity of the novel ketolide HMR 3647 and comparative oral antibiotics against Canadian respiratory tract isolates of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis. Diagn. Microbiol. Infect. Dis. (1999) 35:37-44.
    • (1999) Diagn. Microbiol. Infect. Dis. , vol.35 , pp. 37-44
    • Hoban, D.J.1    Zhanel, G.G.2    Karlowsky, J.A.3
  • 29
    • 0032852568 scopus 로고    scopus 로고
    • In vitro activity of HMR 3647 against Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and beta-haemolytic streptococci
    • WOOTTON M, BOWKER KE, JANOWSKA A, HOLT HA, MACGOWAN AP: In vitro activity of HMR 3647 against Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and beta-haemolytic streptococci. J. Antimicrob. Chemother. (1999) 44:445-453.
    • (1999) J. Antimicrob. Chemother. , vol.44 , pp. 445-453
    • Wootton, M.1    Bowker, K.E.2    Janowska, A.3    Holt, H.A.4    Macgowan, A.P.5
  • 30
    • 0033736847 scopus 로고    scopus 로고
    • Comparative in vitro activity of telithromycin (HMR 3647), three macrolides, amoxycillin, cefdinir and levofloxacin against Gram-positive clinical isolates in Japan
    • OKAMOTO H, MIYAZAKI S, TATEDA K, ISHII Y, YAMAGUCHI K: Comparative in vitro activity of telithromycin (HMR 3647), three macrolides, amoxycillin, cefdinir and levofloxacin against Gram-positive clinical isolates in Japan. J. Antimicrob. Chemother. (2000) 46:797-802.
    • (2000) J. Antimicrob. Chemother. , vol.46 , pp. 797-802
    • Okamoto, H.1    Miyazaki, S.2    Tateda, K.3    Ishii, Y.4    Yamaguchi, K.5
  • 31
    • 0034531990 scopus 로고    scopus 로고
    • In vitro activity of ketolides telithromycin and HMR 3004 against italian isolates of Streptococcus pyogenes and Streptococcus pneumoniae with different erythromycin susceptibility
    • GIOVANETTI E, MONTANARI MP, MARCHETTI F, VARALDO PE: In vitro activity of ketolides telithromycin and HMR 3004 against italian isolates of Streptococcus pyogenes and Streptococcus pneumoniae with different erythromycin susceptibility. J. Antimicrob. Chemother. (2000) 46:905-908.
    • (2000) J. Antimicrob. Chemother. , vol.46 , pp. 905-908
    • Giovanetti, E.1    Montanari, M.P.2    Marchetti, F.3    Varaldo, P.E.4
  • 32
    • 0036732832 scopus 로고    scopus 로고
    • Molecular characterization of macrolide resistance mechanisms among Streptococcus pneumoniae and Streptococcus pyogenes isolated from the PROTEKT 1999-2000 study
    • FARRELL DJ, MORRISSEY I, BAKKER S, FELMINGHAM D: Molecular characterization of macrolide resistance mechanisms among Streptococcus pneumoniae and Streptococcus pyogenes isolated from the PROTEKT 1999-2000 study. J. Antimicrob. Chemother. (2002) 50(Suppl. S1):39-47.
    • (2002) J. Antimicrob. Chemother. , vol.50 , Issue.SUPPL. S1 , pp. 39-47
    • Farrell, D.J.1    Morrissey, I.2    Bakker, S.3    Felmingham, D.4
  • 33
    • 0033962264 scopus 로고    scopus 로고
    • Macrolide resistance and erythromycin resistance determinants among Belgian Streptococcus pyogenes and Streptococcus pneumaniae isolates
    • DESCHEEMAEKER P, CHAPELLE S, LAMMENS C et al.: Macrolide resistance and erythromycin resistance determinants among Belgian Streptococcus pyogenes and Streptococcus pneumaniae isolates. J. Antimicrob. Chemother. (2000) 45:167-173.
    • (2000) J. Antimicrob. Chemother. , vol.45 , pp. 167-173
    • Descheemaeker, P.1    Chapelle, S.2    Lammens, C.3
  • 35
    • 0031879816 scopus 로고    scopus 로고
    • In vitro activities of the ketolide HMR 3647 against recent Gram-positive clinical isolates and Haemophilus influenzae
    • BARRY AL, FUCHS PC, BROWN SD: In vitro activities of the ketolide HMR 3647 against recent Gram-positive clinical isolates and Haemophilus influenzae. Antimicrob. Agents Chemother. (1998) 42:2138-2140.
    • (1998) Antimicrob. Agents Chemother. , vol.42 , pp. 2138-2140
    • Barry, A.L.1    Fuchs, P.C.2    Brown, S.D.3
  • 36
    • 0012633768 scopus 로고    scopus 로고
    • Macrolide resistance by ribosomal mutation in clinical isolates of Streptococcus pneumoniae from the PROTEKT 1999-2000 study
    • FARRELL DJ, DOUTHWAITE S, MORRISSEY I et al.: Macrolide resistance by ribosomal mutation in clinical isolates of Streptococcus pneumoniae from the PROTEKT 1999-2000 study. Antimicrob. Agents Chemother. (2003) 47:1777-1783.
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 1777-1783
    • Farrell, D.J.1    Douthwaite, S.2    Morrissey, I.3
  • 37
    • 0033978875 scopus 로고    scopus 로고
    • In vitro activity of ABT-773, a new ketolide, against recent clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis
    • BRUEGGEMANN AB, DOERN GV, HUYNH HK, WINGERT EM, RHOMBERG PR: In vitro activity of ABT-773, a new ketolide, against recent clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis. Antimicrob. Agents Chemother. (2000) 44:447-449.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 447-449
    • Brueggemann, A.B.1    Doern, G.V.2    Huynh, H.K.3    Wingert, E.M.4    Rhomberg, P.R.5
  • 38
    • 0034969124 scopus 로고    scopus 로고
    • In vitro activity of ABT-773 versus macrolides and quinolones against resistant respiratory tract pathogens
    • DUBOIS J, ST-PIERRE C: In vitro activity of ABT-773 versus macrolides and quinolones against resistant respiratory tract pathogens. Diagn. Microbiol. Infect. Dis. (2001) 40:35-40.
    • (2001) Diagn. Microbiol. Infect. Dis. , vol.40 , pp. 35-40
    • Dubois, J.1    St-Pierre, C.2
  • 40
    • 0034637111 scopus 로고    scopus 로고
    • The complete atomic structure of the large ribosomal subunit at 2.4 A resolution
    • BAN N, NISSEN P, HANSEN J, MOORE PB, STEITZ TA: The complete atomic structure of the large ribosomal subunit at 2.4 A resolution. Science (2000) 289:905-920.
    • (2000) Science , vol.289 , pp. 905-920
    • Ban, N.1    Nissen, P.2    Hansen, J.3    Moore, P.B.4    Steitz, T.A.5
  • 41
    • 0034637161 scopus 로고    scopus 로고
    • The structural basis of ribosome activity in peptide bond synthesis
    • NISSEN P, HANSEN J, BAN N, MOORE PB, STEITZ TA: The structural basis of ribosome activity in peptide bond synthesis. Science (2000) 289:920-930.
    • (2000) Science , vol.289 , pp. 920-930
    • Nissen, P.1    Hansen, J.2    Ban, N.3    Moore, P.B.4    Steitz, T.A.5
  • 42
    • 0034406527 scopus 로고    scopus 로고
    • Inhibition of the ribosomal peptidyl transferase reaction by the mycarose moiety of the antibiotics carbomycin, spiramycin and tylosin
    • POULSEN SM, KOFOED C, VESTER B: Inhibition of the ribosomal peptidyl transferase reaction by the mycarose moiety of the antibiotics carbomycin, spiramycin and tylosin. J. Mol. Biol. (2000) 304:471-481.
    • (2000) J. Mol. Biol. , vol.304 , pp. 471-481
    • Poulsen, S.M.1    Kofoed, C.2    Vester, B.3
  • 43
    • 0034115717 scopus 로고    scopus 로고
    • Macrolide-ketolide inhibition of MLS-resistant ribosomes is improved by alternative drug interaction with domain II of 23S rRNA
    • DOUTHWAITE S, HANSEN LH, MAUVAIS P: Macrolide-ketolide inhibition of MLS-resistant ribosomes is improved by alternative drug interaction with domain II of 23S rRNA. Mol. Microbiol. (2000) 36:183-193.
    • (2000) Mol. Microbiol. , vol.36 , pp. 183-193
    • Douthwaite, S.1    Hansen, L.H.2    Mauvais, P.3
  • 44
    • 0035160878 scopus 로고    scopus 로고
    • Macrolide resistance conferred by base substitutions in 23S rRNA
    • VESTER B, DOUTHWAITE S: Macrolide resistance conferred by base substitutions in 23S rRNA. Antimicrob. Agents Chemother. (2001) 45:1-12.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 1-12
    • Vester, B.1    Douthwaite, S.2
  • 45
    • 0032904341 scopus 로고    scopus 로고
    • A ketolide resistance mutation in domain II of 23S rRNA reveals the proximity of hairpin 35 to the peptidyl transferase centre
    • XIONG L, SHAH S, MAUVAIS P, MANKIN AS: A ketolide resistance mutation in domain II of 23S rRNA reveals the proximity of hairpin 35 to the peptidyl transferase centre. Mol. Microbiol. (1999) 31:633-639.
    • (1999) Mol. Microbiol. , vol.31 , pp. 633-639
    • Xiong, L.1    Shah, S.2    Mauvais, P.3    Mankin, A.S.4
  • 46
    • 0035950132 scopus 로고    scopus 로고
    • Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria
    • SCHLUNZEN F, ZARIVACH R, HARMS J, BASHAN A, TOCILJ A, ALBRECHT R et al.: Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria. Nature (2001) 413:814-821.
    • (2001) Nature , vol.413 , pp. 814-821
    • Schlunzen, F.1    Zarivach, R.2    Harms, J.3    Bashan, A.4    Tocilj, A.5    Albrecht, R.6
  • 48
    • 0033914680 scopus 로고    scopus 로고
    • Mutations in 23S rRNA and ribosomal protein L4 account for resistance in pneumococcal strains selected in vitro by macrolide passage
    • TAIT-KAMRADT A, DAVIES T, CRONAN M, JACOBS MR, APPELBAUM PC, SUTCLIFFE J: Mutations in 23S rRNA and ribosomal protein L4 account for resistance in pneumococcal strains selected in vitro by macrolide passage. Antimicrob. Agents Chemother. (2000) 44:2118-2125.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 2118-2125
    • Tait-Kamradt, A.1    Davies, T.2    Cronan, M.3    Jacobs, M.R.4    Appelbaum, P.C.5    Sutcliffe, J.6
  • 49
    • 0036342198 scopus 로고    scopus 로고
    • The structures of four macrolide antibiotics bound to the large ribosomal subunit
    • HANSEN JL, IPPOLITO JA, BAN N, NISSEN P, MOORE PB, STEITZ TA: The structures of four macrolide antibiotics bound to the large ribosomal subunit. Mol. Cell (2002) 10:117-128.
    • (2002) Mol. Cell , vol.10 , pp. 117-128
    • Hansen, J.L.1    Ippolito, J.A.2    Ban, N.3    Nissen, P.4    Moore, P.B.5    Steitz, T.A.6
  • 50
    • 0034763651 scopus 로고    scopus 로고
    • Structures of ketolides and macrolides determine their mode of interaction with the ribosomal target site
    • DOUTHWAITE S, CHAMPNEY WS: Structures of ketolides and macrolides determine their mode of interaction with the ribosomal target site. J. Antimicrob. Chemother. (2001) 48(Suppl. T1):1-8.
    • (2001) J. Antimicrob. Chemother. , vol.48 , Issue.SUPPL. T1 , pp. 1-8
    • Douthwaite, S.1    Champney, W.S.2
  • 51
    • 0035342162 scopus 로고    scopus 로고
    • Bacterial ribosomal subunit synthesis: A novel antibiotic target
    • CHAMPNEY WS: Bacterial ribosomal subunit synthesis: a novel antibiotic target. Curr. Drug Targets Infect. Disord. (2001) 1:19-36.
    • (2001) Curr. Drug Targets Infect. Disord. , vol.1 , pp. 19-36
    • Champney, W.S.1
  • 52
    • 0021064473 scopus 로고
    • Site of action of a ribosomal RNA methylase responsible for resistance to erythromycin and other antibiotics
    • SKINNER R, CUNDLIFFE E, SCHMIDT FJ: Site of action of a ribosomal RNA methylase responsible for resistance to erythromycin and other antibiotics. J. Biol. Chem. (1983) 258:12702-12706.
    • (1983) J. Biol. Chem. , vol.258 , pp. 12702-12706
    • Skinner, R.1    Cundliffe, E.2    Schmidt, F.J.3
  • 54
    • 0038474136 scopus 로고    scopus 로고
    • Structural consideration of macrolide antibiotics in relation to the ribosomal interaction and drug design
    • TAKASHIMA H: Structural consideration of macrolide antibiotics in relation to the ribosomal interaction and drug design. Curr. Top. Med. Chem. (2003) 3:991-999.
    • (2003) Curr. Top. Med. Chem. , vol.3 , pp. 991-999
    • Takashima, H.1
  • 55
    • 0028914553 scopus 로고
    • Insights into erythromycin action from studies of its activity as inducer of resistance
    • WEISBLUM B: Insights into erythromycin action from studies of its activity as inducer of resistance. Antimicrob. Agents Chemother. (1995) 39:797-805.
    • (1995) Antimicrob. Agents Chemother. , vol.39 , pp. 797-805
    • Weisblum, B.1
  • 56
    • 0037083024 scopus 로고    scopus 로고
    • Mechanisms of resistance to macrolides and lincosamides: Nature of the resistance elements and their clinical implications
    • LECLERCQ R: Mechanisms of resistance to macrolides and lincosamides: nature of the resistance elements and their clinical implications. Clin. Infect. Dis. (2002) 34:482-492.
    • (2002) Clin. Infect. Dis. , vol.34 , pp. 482-492
    • Leclercq, R.1
  • 57
    • 0028963496 scopus 로고
    • Erythromycin resistance by ribosome modification
    • WEISBLUM B: Erythromycin resistance by ribosome modification. Antimicrob. Agents Chemother. (1995) 39:577-585.
    • (1995) Antimicrob. Agents Chemother. , vol.39 , pp. 577-585
    • Weisblum, B.1
  • 58
    • 0034425847 scopus 로고    scopus 로고
    • Two new mechanisms of macrolide resistance in clinical strains of Streptococcus pneumoniae from Eastern Europe and North America
    • TAIT-KAMRADT A, DAVIES T, APPELBAUM PC et al.: Two new mechanisms of macrolide resistance in clinical strains of Streptococcus pneumoniae from Eastern Europe and North America. Antimicrob. Agents Chemother. (2000) 44:3395-3401.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 3395-3401
    • Tait-Kamradt, A.1    Davies, T.2    Appelbaum, P.C.3
  • 59
    • 0036137010 scopus 로고    scopus 로고
    • Diversity of ribosomal mutations conferring resistance to macrolides, clindamycin, streptogramin and telithromycin in Streptococcus pneumoniae
    • CANU A, MALBRUNY B, COQUEMONT M, DAVIES TA, APPELBAUM PC, LECLERCQ R: Diversity of ribosomal mutations conferring resistance to macrolides, clindamycin, streptogramin and telithromycin in Streptococcus pneumoniae. Antimicrob. Agents Chemother. (2002) 46:125-131.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 125-131
    • Canu, A.1    Malbruny, B.2    Coquemont, M.3    Davies, T.A.4    Appelbaum, P.C.5    Leclercq, R.6
  • 60
    • 0034512059 scopus 로고    scopus 로고
    • The role of efflux in macrolide resistance
    • ZHONG P, SHORTRIDGE VD: The role of efflux in macrolide resistance. Drug Resist. Update (2000) 3:325-329.
    • (2000) Drug Resist. Update , vol.3 , pp. 325-329
    • Zhong, P.1    Shortridge, V.D.2
  • 61
    • 0034956121 scopus 로고    scopus 로고
    • Macrolide-resistant Streptococcus pneumoniae in Canada during 1998-1999: Prevalence of mef(A) and erm(B) and susceptibilities to ketolides
    • HOBAN DJ, WIERZBOWSKI AK, NICHOL K, ZHANEL GG: Macrolide-resistant Streptococcus pneumoniae in Canada during 1998-1999: prevalence of mef(A) and erm(B) and susceptibilities to ketolides. Antimicrob. Agents Chemother. (2001) 45:2147-2150.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 2147-2150
    • Hoban, D.J.1    Wierzbowski, A.K.2    Nichol, K.3    Zhanel, G.G.4
  • 62
    • 0037470942 scopus 로고    scopus 로고
    • Characteristic expression of three genes, msr(A), mph(C) and erm(Y), that confer resistance to macrolide antibiotics on Staphylococcus aureus
    • MATSUOKA M, INOUE M, ENDO Y, NAKAJIMA Y: Characteristic expression of three genes, msr(A), mph(C) and erm(Y), that confer resistance to macrolide antibiotics on Staphylococcus aureus. FEMS Microbiol. Lett. (2003) 220:287-293.
    • (2003) FEMS Microbiol. Lett. , vol.220 , pp. 287-293
    • Matsuoka, M.1    Inoue, M.2    Endo, Y.3    Nakajima, Y.4
  • 63
    • 0037006971 scopus 로고    scopus 로고
    • Antibiotic resistance peptides: Interaction of peptides conferring macrolide and ketolide resistance with Staphylococcus aureus ribosomes: Conformation of bound peptides as determined by transferred NOE experiments
    • VERDIER L, GHARBI-BENAROUS J, BERTHO G, MAUVAIS P, GIRAULT JP: Antibiotic resistance peptides: interaction of peptides conferring macrolide and ketolide resistance with Staphylococcus aureus ribosomes: conformation of bound peptides as determined by transferred NOE experiments. Biochemistry (2002) 41:4218-4229.
    • (2002) Biochemistry , vol.41 , pp. 4218-4229
    • Verdier, L.1    Gharbi-Benarous, J.2    Bertho, G.3    Mauvais, P.4    Girault, J.P.5
  • 64
    • 0035873488 scopus 로고    scopus 로고
    • Worldwide prevalence of antimicrobial resistance in Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis in the SENTRY Antimicrobial Surveillance Program, 1997-1999
    • HOBAN DJ, DOERN GV, FLUIT AC, ROUSSEL-DELVALLEZ M, JONES RN: Worldwide prevalence of antimicrobial resistance in Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis in the SENTRY Antimicrobial Surveillance Program, 1997-1999. Clin. Infect. Dis. (2001) 32(Suppl. 2):S81-S93.
    • (2001) Clin. Infect. Dis. , vol.32 , Issue.SUPPL. 2
    • Hoban, D.J.1    Doern, G.V.2    Fluit, A.C.3    Roussel-Delvallez, M.4    Jones, R.N.5
  • 65
    • 0036343455 scopus 로고    scopus 로고
    • The ketolides: A critical review
    • ZHANEL GG, WALTERS M, NOREDDIN A et al.: The ketolides: a critical review. Drugs (2002) 62:1771-1804.
    • (2002) Drugs , vol.62 , pp. 1771-1804
    • Zhanel, G.G.1    Walters, M.2    Noreddin, A.3
  • 66
    • 0036782870 scopus 로고    scopus 로고
    • Ketolides: The future of the macrolides?
    • NILIUS AM, MA Z: Ketolides: the future of the macrolides? Curr. Opin. Pharmacol. (2002) 2:493-500.
    • (2002) Curr. Opin. Pharmacol. , vol.2 , pp. 493-500
    • Nilius, A.M.1    Ma, Z.2
  • 68
    • 0035228142 scopus 로고    scopus 로고
    • Safeguarding future antimicrobial options: Strategies to minimize resistance
    • LECLERCQ R: Safeguarding future antimicrobial options: strategies to minimize resistance. Clin. Microbiol. Infect. (2001) 7(Suppl. 3):18-23.
    • (2001) Clin. Microbiol. Infect. , vol.7 , Issue.SUPPL. 3 , pp. 18-23
    • Leclercq, R.1
  • 70
    • 0032755509 scopus 로고    scopus 로고
    • Induction of ribosome methylation in MLS-resistant Streptococcus pneumoniae by mactolides and ketolides
    • ZHONG P, CAO Z, HAMMOND R et al.: Induction of ribosome methylation in MLS-resistant Streptococcus pneumoniae by mactolides and ketolides. Microb. Drug Resist. (1999) 5:183-188.
    • (1999) Microb. Drug Resist. , vol.5 , pp. 183-188
    • Zhong, P.1    Cao, Z.2    Hammond, R.3
  • 71
    • 0033948620 scopus 로고    scopus 로고
    • Conformations in solution and bound to bacterial ribosomes of ketolides, HMR 3647 (telithromycin) and RU 72366: A new class of highly potent antibacterials
    • EVRARD-TODESCHI N, GHARBI-BENAROUS J, GAILLET C et al.: Conformations in solution and bound to bacterial ribosomes of ketolides, HMR 3647 (telithromycin) and RU 72366: a new class of highly potent antibacterials. Bioorg. Med. Chem. (2000) 8:1579-1597.
    • (2000) Bioorg. Med. Chem. , vol.8 , pp. 1579-1597
    • Evrard-Todeschi, N.1    Gharbi-Benarous, J.2    Gaillet, C.3
  • 72
    • 0032950956 scopus 로고    scopus 로고
    • The macrolide-ketolide antibiotic binding site is formed by structures in domains II and V of 23S ribosomal RNA
    • HANSEN LH, MAUVAIS P, DOUTHWAITE S: The macrolide-ketolide antibiotic binding site is formed by structures in domains II and V of 23S ribosomal RNA. Mol. Microbiol. (1999) 31:623-631.
    • (1999) Mol. Microbiol. , vol.31 , pp. 623-631
    • Hansen, L.H.1    Mauvais, P.2    Douthwaite, S.3
  • 73
    • 0035162904 scopus 로고    scopus 로고
    • Binding site of macrolide antibiotics on the ribosome: New resistance mutation identifies a specific interaction of ketolides with rRNA
    • GARZA-RAMOS G, XIONG L, ZHONG P, MANKIN A: Binding site of macrolide antibiotics on the ribosome: new resistance mutation identifies a specific interaction of ketolides with rRNA. J. Bacteriol. (2001) 183:6898-6907.
    • (2001) J. Bacteriol. , vol.183 , pp. 6898-6907
    • Garza-Ramos, G.1    Xiong, L.2    Zhong, P.3    Mankin, A.4
  • 74
    • 0034075717 scopus 로고    scopus 로고
    • Studies of the novel ketolide ABT-773: Transport, binding to ribosomes and inhibition of protein synthesis in Streptococcus pneumoniae
    • CAPOBIANCO JO, CAO Z, SHORTRIDGE VD, MA Z, FLAMM RK, ZHONG P: Studies of the novel ketolide ABT-773: transport, binding to ribosomes and inhibition of protein synthesis in Streptococcus pneumoniae. Antimicrob. Agents Chemother. (2000) 44:1562-1567.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 1562-1567
    • Capobianco, J.O.1    Cao, Z.2    Shortridge, V.D.3    Ma, Z.4    Flamm, R.K.5    Zhong, P.6
  • 75
    • 0035224671 scopus 로고    scopus 로고
    • Structure-activity relationships of ketolides versus macrolides
    • DOUTHWAITE S: Structure-activity relationships of ketolides versus macrolides. Clin. Microbiol. Infect. (2001) 7(Suppl. 3):11-17.
    • (2001) Clin. Microbiol. Infect. , vol.7 , Issue.SUPPL. 3 , pp. 11-17
    • Douthwaite, S.1
  • 76
    • 0037342872 scopus 로고    scopus 로고
    • Drugs of the 21st century: Telithromycin (HMR 3647)-the first ketolide
    • ACKERMANN G, RODLOFF AC: Drugs of the 21st century: telithromycin (HMR 3647)-the first ketolide. J. Antimicrob. Chemother. (2003) 51:497-511.
    • (2003) J. Antimicrob. Chemother. , vol.51 , pp. 497-511
    • Ackermann, G.1    Rodloff, A.C.2
  • 77
    • 0344889213 scopus 로고    scopus 로고
    • In vitro activities of ketolides HMR 3647 and HMR 3004, levofloxacin and other quinolones and macrolides against Neisseria spp. and Moraxella catarrhalis
    • SAEZ-NIETO JA, VAZQUEZ JA: In vitro activities of ketolides HMR 3647 and HMR 3004, levofloxacin and other quinolones and macrolides against Neisseria spp. and Moraxella catarrhalis. Antimicrob. Agents Chemother. (1999) 43:983-984.
    • (1999) Antimicrob. Agents Chemother. , vol.43 , pp. 983-984
    • Saez-Nieto, J.A.1    Vazquez, J.A.2
  • 78
    • 0037764675 scopus 로고    scopus 로고
    • Antimicrobial resistance in Haemophilus influenzae and Moraxella catarrhalis respiratory tract isolates: Results of the Canadian Respiratory Organism Susceptibility Study, 1997 to 2002
    • ZHANEL GG, PALATNICK L, NICHOL KA, LOW DE, HOBAN DJ: Antimicrobial resistance in Haemophilus influenzae and Moraxella catarrhalis respiratory tract isolates: results of the Canadian Respiratory Organism Susceptibility Study, 1997 to 2002. Antimicrob. Agents Chemother. (2003) 47:1875-1881.
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 1875-1881
    • Zhanel, G.G.1    Palatnick, L.2    Nichol, K.A.3    Low, D.E.4    Hoban, D.J.5
  • 80
    • 0031780527 scopus 로고    scopus 로고
    • Comparative antimicrobial activity and kill-curve investigations of novel ketolide antimicrobial agents (HMR 3004 and HMR 3647) tested against Haemophilus influenzae and Moraxella catarrhalis strains
    • BIEDENBACH DJ, BARRETT MS, JONES RN: Comparative antimicrobial activity and kill-curve investigations of novel ketolide antimicrobial agents (HMR 3004 and HMR 3647) tested against Haemophilus influenzae and Moraxella catarrhalis strains. Diagn. Microbiol. Infect. Dis. (1998) 31:349-353.
    • (1998) Diagn. Microbiol. Infect. Dis. , vol.31 , pp. 349-353
    • Biedenbach, D.J.1    Barrett, M.S.2    Jones, R.N.3
  • 82
    • 0031755086 scopus 로고    scopus 로고
    • Activity of HMR 3647 compared to those of five agents against Haemophilus influenzae and Moraxella catarrhalis by MIC determination and time-kill assay
    • PANKUCH GA, HOELLMAN DB, LIN G, BAJAKSOUZIAN S, JACOBS MR, APPELBAUM PC: Activity of HMR 3647 compared to those of five agents against Haemophilus influenzae and Moraxella catarrhalis by MIC determination and time-kill assay. Antimicrob. Agents Chemother. (1998) 42:3032-3034.
    • (1998) Antimicrob. Agents Chemother. , vol.42 , pp. 3032-3034
    • Pankuch, G.A.1    Hoellman, D.B.2    Lin, G.3    Bajaksouzian, S.4    Jacobs, M.R.5    Appelbaum, P.C.6
  • 83
    • 0036194468 scopus 로고    scopus 로고
    • Ketolides in the treatment of respiratory infections
    • ZHANEL GG, HOBAN DJ: Ketolides in the treatment of respiratory infections. Expert Opin. Pharmacother. (2002) 3:277-297.
    • (2002) Expert Opin. Pharmacother. , vol.3 , pp. 277-297
    • Zhanel, G.G.1    Hoban, D.J.2
  • 84
    • 0034090751 scopus 로고    scopus 로고
    • In vitro activity of telithromycin (HMR3647), a new ketolide, against clinical isolates of Mycoplasma pneumoniae in Japan
    • YAMAGUCHI T, HIRAKATA Y, IZUMIKAWA K et al.: In vitro activity of telithromycin (HMR3647), a new ketolide, against clinical isolates of Mycoplasma pneumoniae in Japan. Antimicrob. Agents Chemother. (2000) 44:1381-1382.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 1381-1382
    • Yamaguchi, T.1    Hirakata, Y.2    Izumikawa, K.3
  • 85
    • 0033933613 scopus 로고    scopus 로고
    • Comparative activities of telithromycin (HMR 3647), levofloxacin and other antimicrobial agents against human mycoplasmas
    • BEBEAR CM, RENAUDIN H, BRYSKIER A, BEBEAR C: Comparative activities of telithromycin (HMR 3647), levofloxacin and other antimicrobial agents against human mycoplasmas. Antimicrob. Agents Chemother. (2000) 44:1980-1982.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 1980-1982
    • Bebear, C.M.1    Renaudin, H.2    Bryskier, A.3    Bebear, C.4
  • 86
    • 0032906803 scopus 로고    scopus 로고
    • In vitro activity of the ketolide HMR 3647 (RU 6647) for Legionella spp, its pharmacokinetics in guinea-pigs and use of the drug to treat guinea-pigs with Legionella pneumophila pneumonia
    • EDELSTEIN PH, EDELSTEIN MA: In vitro activity of the ketolide HMR 3647 (RU 6647) for Legionella spp, its pharmacokinetics in guinea-pigs and use of the drug to treat guinea-pigs with Legionella pneumophila pneumonia. Antimicrob. Agents Chemother. (1999) 43:90-95.
    • (1999) Antimicrob. Agents Chemother. , vol.43 , pp. 90-95
    • Edelstein, P.H.1    Edelstein, M.A.2
  • 88
    • 0031860252 scopus 로고    scopus 로고
    • In vitro activity of a new ketolide antibiotic, HMR 3647, against Chlamydia pneumoniae
    • ROBLIN PM, HAMMERSCHLAG MR: In vitro activity of a new ketolide antibiotic, HMR 3647, against Chlamydia pneumoniae. Antimicrob. Agents Chemother. (1998) 42:1515-1516.
    • (1998) Antimicrob. Agents Chemother. , vol.42 , pp. 1515-1516
    • Roblin, P.M.1    Hammerschlag, M.R.2
  • 89
    • 0034062940 scopus 로고    scopus 로고
    • In vitro activity of ABT-773, a new ketolide antibiotic, against Chlamydia pneumoniae
    • STRIGL S, ROBLIN PM, REZNIK T, HAMMERSCHLAG MR: In vitro activity of ABT-773, a new ketolide antibiotic, against Chlamydia pneumoniae. Antimicrob. Agents Chemother. (2000) 44:1112-1113.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 1112-1113
    • Strigl, S.1    Roblin, P.M.2    Reznik, T.3    Hammerschlag, M.R.4
  • 90
    • 0038262691 scopus 로고    scopus 로고
    • Streptococcuspyogenes isolates with characterized macrolide resistance mechanisms in Spain: In vitro activities of telithromycin and cethromycin
    • MOROSINI MI, CANTON R, LOZA E, DEL CAMPO R, ALMARAZ F, BAQUERO F: Streptococcuspyogenes isolates with characterized macrolide resistance mechanisms in Spain: in vitro activities of telithromycin and cethromycin. J. Antimicrob. Chemother. (2003) 52:50-55.
    • (2003) J. Antimicrob. Chemother. , vol.52 , pp. 50-55
    • Morosini, M.I.1    Canton, R.2    Loza, E.3    Del Campo, R.4    Almaraz, F.5    Baquero, F.6
  • 91
    • 0036146565 scopus 로고    scopus 로고
    • Susceptibility to telithromycin in 1,011 Streptococcus pyogenes isolates from 10 central and Eastern European countries
    • NAGAI K, APPELBAUM PC, DAVIES TA et al.: Susceptibility to telithromycin in 1,011 Streptococcus pyogenes isolates from 10 central and Eastern European countries. Antimicrob. Agents Chemother. (2002) 46:546-549.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 546-549
    • Nagai, K.1    Appelbaum, P.C.2    Davies, T.A.3
  • 92
    • 0032818229 scopus 로고    scopus 로고
    • Phenotypes and genotypes of erythromycin-resistant Streptococcuspyogenes strains in Italy and heterogeneity of inducibly resistant strains
    • GIOVANETTI E, MONTANARI MP, MINGOIA M, VARALDO PE: Phenotypes and genotypes of erythromycin-resistant Streptococcuspyogenes strains in Italy and heterogeneity of inducibly resistant strains. Antimicrob. Agents Chemother. (1999) 43:1935-1940.
    • (1999) Antimicrob. Agents Chemother. , vol.43 , pp. 1935-1940
    • Giovanetti, E.1    Montanari, M.P.2    Mingoia, M.3    Varaldo, P.E.4
  • 93
    • 0036124421 scopus 로고    scopus 로고
    • In vitro activity of new ketolides against macrolide-susceptible and -resistant Staphylococcus aureus isolates with defined resistance gene status
    • SCHMITZ FJ, PETRIDOU J, MILATOVIC D, VERHOEF J, FLUIT AC, SCHWARZ S: In vitro activity of new ketolides against macrolide-susceptible and -resistant Staphylococcus aureus isolates with defined resistance gene status. J. Antimicrob. Chemother. (2002) 49:580-582.
    • (2002) J. Antimicrob. Chemother. , vol.49 , pp. 580-582
    • Schmitz, F.J.1    Petridou, J.2    Milatovic, D.3    Verhoef, J.4    Fluit, A.C.5    Schwarz, S.6
  • 94
    • 0032892037 scopus 로고    scopus 로고
    • In vitro activities of two ketolides, HMR 3647 and HMR 3004, against Gram-positive bacteria
    • MALATHUM K, COQUE TM, SINGH KV, MURRAY BE: In vitro activities of two ketolides, HMR 3647 and HMR 3004, against Gram-positive bacteria. Amimicrob. Agents Chemother. (1999) 43:930-936.
    • (1999) Amimicrob. Agents Chemother. , vol.43 , pp. 930-936
    • Malathum, K.1    Coque, T.M.2    Singh, K.V.3    Murray, B.E.4
  • 95
    • 0035164494 scopus 로고    scopus 로고
    • Susceptibilities of Haemophilus influenzae and Moraxella catarrhalis to ABT-773 compared to their susceptibilities to 11 other agents
    • CREDITO KL, LIN G, PANKUCH GA, BAJAKSOUZIAN S, JACOBS MR, APPELBAUM PC: Susceptibilities of Haemophilus influenzae and Moraxella catarrhalis to ABT-773 compared to their susceptibilities to 11 other agents. Antimicrob. Agents Chemother. (2001) 45:67-72.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 67-72
    • Credito, K.L.1    Lin, G.2    Pankuch, G.A.3    Bajaksouzian, S.4    Jacobs, M.R.5    Appelbaum, P.C.6
  • 96
    • 0035215955 scopus 로고    scopus 로고
    • In vitro activity of ABT-773, telithromycin and eight other antimicrobials against eryrhromycin-resistant Streptococcus pneumoniae respiratory isolates of children
    • JOHNSON CN, BENJAMIN WH JR, GREY BM, CRAIN MC, EDWARDS KM, WAITES KB: In vitro activity of ABT-773, telithromycin and eight other antimicrobials against eryrhromycin-resistant Streptococcus pneumoniae respiratory isolates of children. Int. J. Antimicrob. Agents (2001) 18:531-535.
    • (2001) Int. J. Antimicrob. Agents , vol.18 , pp. 531-535
    • Johnson, C.N.1    Benjamin Jr., W.H.2    Grey, B.M.3    Crain, M.C.4    Edwards, K.M.5    Waites, K.B.6
  • 97
    • 0034962543 scopus 로고    scopus 로고
    • Comparative in vitro activity of ABT-773, a novel antibacterial ketolide
    • NILIUS AM, BUI MH, ALMER L et a.: Comparative in vitro activity of ABT-773, a novel antibacterial ketolide. Antimicrob. Agents Chemother. (2001) 45:2163-2168.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 2163-2168
    • Nilius, A.M.1    Bui, M.H.2    Almer, L.3
  • 98
    • 0035180516 scopus 로고    scopus 로고
    • In vitro activities of a new ketolide, ABT-773, against multi-drug resistant Gram-positive cocci
    • SINGH KV, MALATHUM K, MURRAY BE: In vitro activities of a new ketolide, ABT-773, against multi-drug resistant Gram-positive cocci. Antimicrob. Agents Chemother. (2001) 45:3640-3643.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 3640-3643
    • Singh, K.V.1    Malathum, K.2    Murray, B.E.3
  • 99
    • 0036153973 scopus 로고    scopus 로고
    • Comparative in vitro activity of ABT-773 and two macrolides against staphylococci
    • VON EIFF C, PETERS G: Comparative in vitro activity of ABT-773 and two macrolides against staphylococci. J. Antimicrob. Chemother. (2002) 49:189-192.
    • (2002) J. Antimicrob. Chemother. , vol.49 , pp. 189-192
    • Von Eiff, C.1    Peters, G.2
  • 100
    • 0037228773 scopus 로고    scopus 로고
    • In vitro activities of ABT-773 and other antimicrobials against human mycoplasmas
    • WAITES KB, CRABB DM, DUFFY LB: In vitro activities of ABT-773 and other antimicrobials against human mycoplasmas. Antimicrob. Agents Chemother. (2003) 47:39-42.
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 39-42
    • Waites, K.B.1    Crabb, D.M.2    Duffy, L.B.3
  • 102
  • 103
    • 0033728021 scopus 로고    scopus 로고
    • Pharmacokinetics and comparative effects of telithromycin (HMR 3647) and clarithromycin on the oropharyngeal and intestinal microflora
    • EDLUND C, ALVAN G, BARKHOLT L, VACHERON F, NORD CE: Pharmacokinetics and comparative effects of telithromycin (HMR 3647) and clarithromycin on the oropharyngeal and intestinal microflora. J. Antimicrob. Chemother. (2000) 46:741-749.
    • (2000) J. Antimicrob. Chemother. , vol.46 , pp. 741-749
    • Edlund, C.1    Alvan, G.2    Barkholt, L.3    Vacheron, F.4    Nord, C.E.5
  • 105
    • 0036911498 scopus 로고    scopus 로고
    • Pharmacokinetics and absolute oral bioavailability of an 800-mg oral dose of telithromycin in healthy young and elderly volunteers
    • PERRET C, LENFANT B, WEINLING E: et al.: Pharmacokinetics and absolute oral bioavailability of an 800-mg oral dose of telithromycin in healthy young and elderly volunteers. Chemotherapy (2002) 48:217-223.
    • (2002) Chemotherapy , vol.48 , pp. 217-223
    • Perret, C.1    Lenfant, B.2    Weinling, E.3
  • 106
    • 0036014488 scopus 로고    scopus 로고
    • Pharmacodynamic rationale for short-duration antibacterial therapy
    • NICOLAU DP: Pharmacodynamic rationale for short-duration antibacterial therapy. J. Infect. (2002) 44(Suppl. A):17-23.
    • (2002) J. Infect. , vol.44 , Issue.SUPPL. A , pp. 17-23
    • Nicolau, D.P.1
  • 107
    • 0035992158 scopus 로고    scopus 로고
    • Penetration of telithromycin (HMR 3647), a new ketolide antimicrobial, into inflammatory blister fluid following oral administration
    • NAMOUR F, SULTAN E, PASCUAL MH, LENFANT B: Penetration of telithromycin (HMR 3647), a new ketolide antimicrobial, into inflammatory blister fluid following oral administration. J. Antimicrob. Chemother. (2002) 49:1035-1038.
    • (2002) J. Antimicrob. Chemother. , vol.49 , pp. 1035-1038
    • Namour, F.1    Sultan, E.2    Pascual, M.H.3    Lenfant, B.4
  • 108
    • 0035052794 scopus 로고    scopus 로고
    • Antibacterial activity of telithromycin (HMR 3647) in relation to in vitro simulated human plasma kinetics
    • BONNEFOY A, LE PRIOL P: Antibacterial activity of telithromycin (HMR 3647) in relation to in vitro simulated human plasma kinetics. J. Antimicrob. Chemother. (2001) 47:471-473.
    • (2001) J. Antimicrob. Chemother. , vol.47 , pp. 471-473
    • Bonnefoy, A.1    Le Priol, P.2
  • 110
    • 0035262142 scopus 로고    scopus 로고
    • Uptake and intracellular activity of ketolide HMR 3647 in human phagocytic and non-phagocytic cells
    • PASCUAL A, BALLESTA S, GARCIA I, PEREA EJ: Uptake and intracellular activity of ketolide HMR 3647 in human phagocytic and non-phagocytic cells. Clin. Microbiol. Infect. (2001) 7:65-69.
    • (2001) Clin. Microbiol. Infect. , vol.7 , pp. 65-69
    • Pascual, A.1    Ballesta, S.2    Garcia, I.3    Perea, E.J.4
  • 111
    • 0032841480 scopus 로고    scopus 로고
    • The new ketolide HMR3647 accumulates in the azurophil granules of human polymorphonuclear cells
    • MIOSSEC-BARTOLI C, PILATRE L, PEYRON P et al.: The new ketolide HMR3647 accumulates in the azurophil granules of human polymorphonuclear cells. Antimicrob. Agents Chemother. (1999) 43:2457-2462.
    • (1999) Antimicrob. Agents Chemother. , vol.43 , pp. 2457-2462
    • Miossec-Bartoli, C.1    Pilatre, L.2    Peyron, P.3
  • 112
    • 0031879813 scopus 로고    scopus 로고
    • Interactions between HMR 3647, a new ketolide and human polymorphonudear neutrophils
    • VAZIFEH D, PREIRA A, BRYSKIER A, LABRO MT: Interactions between HMR 3647, a new ketolide and human polymorphonudear neutrophils. Antimicrob. Agents Chemother. (1998) 42:1944-1951.
    • (1998) Antimicrob. Agents Chemother. , vol.42 , pp. 1944-1951
    • Vazifeh, D.1    Preira, A.2    Bryskier, A.3    Labro, M.T.4
  • 114
    • 0034980950 scopus 로고    scopus 로고
    • Telithromycin
    • discussion 830-831
    • BALFOUR JA, FIGGITT DP: Telithromycin. Drugs (2001) 61:815-29; discussion 830-831.
    • (2001) Drugs , vol.61 , pp. 815-829
    • Balfour, J.A.1    Figgitt, D.P.2
  • 115
    • 0034790746 scopus 로고    scopus 로고
    • Telithromycin: An oral ketolide for respiratory infections
    • BEARDEN DT, NEUHAUSER MM, GAREY KW. Telithromycin: an oral ketolide for respiratory infections. Pharmacotherapy (2001) 21:1204-1222.
    • (2001) Pharmacotherapy , vol.21 , pp. 1204-1222
    • Bearden, D.T.1    Neuhauser, M.M.2    Garey, K.W.3
  • 116
    • 0036194907 scopus 로고    scopus 로고
    • Telithromycin: The first of the ketolides
    • SHAIN CS, AMSDEN GW: Telithromycin: the first of the ketolides. Ann. Pharmacother. (2002) 36:452-464.
    • (2002) Ann. Pharmacother. , vol.36 , pp. 452-464
    • Shain, C.S.1    Amsden, G.W.2
  • 117
    • 0037374044 scopus 로고    scopus 로고
    • Effect of single and repeated oral doses of telithromycin on cardiac QT interval in healthy subjects
    • DEMOLIS JL, VACHERON F, CARDUS S, FUNCK-BRENTANO C: Effect of single and repeated oral doses of telithromycin on cardiac QT interval in healthy subjects. Clin. Pharmacol. Ther. (2003) 73:242-252.
    • (2003) Clin. Pharmacol. Ther. , vol.73 , pp. 242-252
    • Demolis, J.L.1    Vacheron, F.2    Cardus, S.3    Funck-Brentano, C.4
  • 121
    • 0034117631 scopus 로고    scopus 로고
    • Postantibiotic suppression of growth of erythromycin A-susceptible and -resistant gram-positive bacteria by the ketolides telithromycin (HMR 3647) and HMR 3004
    • MUNCKHOF WJ, BORLACE G, TURNIDGE JD: Postantibiotic suppression of growth of erythromycin A-susceptible and -resistant gram-positive bacteria by the ketolides telithromycin (HMR 3647) and HMR 3004. Antimicrob. Agents Chemother. (2000) 44(6):1749-1753.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , Issue.6 , pp. 1749-1753
    • Munckhof, W.J.1    Borlace, G.2    Turnidge, J.D.3
  • 128
    • 0036451201 scopus 로고    scopus 로고
    • Efficacy and safety of telithromycin in community-acquired pneumonia
    • VAN RENSBURG DJ, MATTHEWS PA, LEROY B: Efficacy and safety of telithromycin in community-acquired pneumonia. Curr. Med. Res. Opin. (2002) 18:397-400.
    • (2002) Curr. Med. Res. Opin. , vol.18 , pp. 397-400
    • Van Rensburg, D.J.1    Matthews, P.A.2    Leroy, B.3
  • 129
    • 0345963059 scopus 로고    scopus 로고
    • Clinical and bacteriological efficacy of telithromycin versus clarithromycin in patients with community-acquired pneumonia due to Streptococcus pneumoniae, including erythromycin-resistant strains
    • PULLMAN J, BOUCHER P, LAVIN B, PATEL M: Clinical and bacteriological efficacy of telithromycin versus clarithromycin in patients with community-acquired pneumonia due to Streptococcus pneumoniae, including erythromycin-resistant strains (abstract no. 372). 41st Interscience Conference on Antimicrobial Agents and Chemotherapy; 2001 Sept 22-25; Chicago, USA (2001).
    • (2001) 41st Interscience Conference on Antimicrobial Agents and Chemotherapy; 2001 Sept 22-25; Chicago, USA
    • Pullman, J.1    Boucher, P.2    Lavin, B.3    Patel, M.4
  • 130
    • 0036452858 scopus 로고    scopus 로고
    • Efficacy and tolerability of once-daily telithromycin compared with high-dose amoxicillin for treatment of community-acquired pneumonia
    • HAGBERG L, TORRES A, VAN RENSBURG D, LEROY B, RANGARAJU M, RUUTH E: Efficacy and tolerability of once-daily telithromycin compared with high-dose amoxicillin for treatment of community-acquired pneumonia. Infection (2002) 30:378-386.
    • (2002) Infection , vol.30 , pp. 378-386
    • Hagberg, L.1    Torres, A.2    Van Rensburg, D.3    Leroy, B.4    Rangaraju, M.5    Ruuth, E.6
  • 132
    • 0347854429 scopus 로고    scopus 로고
    • Oral telithromycin (HMR 3647) 800 mg once daily for 5 days and 10 days is well-tolerated and as effective as amoxicillin/clavulanic acid 500/125 mg three-times daily for 10 days in acute maxillary sinusitis (AMS) in adults
    • TELLIER G, LASKO B, LEROY B, SIDAROUS E, ANDRADE C: Oral telithromycin (HMR 3647) 800 mg once daily for 5 days and 10 days is well-tolerated and as effective as amoxicillin/clavulanic acid 500/125 mg three-times daily for 10 days in acute maxillary sinusitis (AMS) in adults (abstract no. 2226). 40th Interscience Conference on Antimicrobial Agents and Chemotherapy; 2000 Sept 17-20, Toronto, Canada (2000).
    • (2000) 40th Interscience Conference on Antimicrobial Agents and Chemotherapy; 2000 Sept 17-20, Toronto, Canada
    • Tellier, G.1    Lasko, B.2    Leroy, B.3    Sidarous, E.4    Andrade, C.5
  • 133
    • 0036828205 scopus 로고    scopus 로고
    • Telithromycin is as effective as amoxicillin/clavulanate in acute exacerbations of chronic bronchitis
    • AUBIER M, ALDONS PM, LEAK et al.: Telithromycin is as effective as amoxicillin/clavulanate in acute exacerbations of chronic bronchitis. Respir. Med. (2002) 96:862-871.
    • (2002) Respir. Med. , vol.96 , pp. 862-871
    • Aubier, M.1    Aldons, P.M.2    Leak3
  • 134
    • 0346594371 scopus 로고    scopus 로고
    • Oral telithromycin (HMR 3647) 800 mg once daily for 5 days is well-tolerated and as effective as cefuroxime axetil 500 mg twice daily for 10 days in adults with acute exacerbations of chronic bronchitis (AECB)
    • DEABATE C, HEYDER A, LEROY B: Oral telithromycin (HMR 3647) 800 mg once daily for 5 days is well-tolerated and as effective as cefuroxime axetil 500 mg twice daily for 10 days in adults with acute exacerbations of chronic bronchitis (AECB) (abstract no. 2228). 40th Interscience Conference on Antimicrobial Agents and Chemotherapy; 2000 Sept 17-20; Toronto, Canada (2000).
    • (2000) 40th Interscience Conference on Antimicrobial Agents and Chemotherapy; 2000 Sept 17-20; Toronto, Canada
    • Deabate, C.1    Heyder, A.2    Leroy, B.3
  • 135
    • 0347854428 scopus 로고    scopus 로고
    • Telithromycin treatment of CAP is associated with lower usage of additional RTI-related antibiotics than high-dose amoxycillin in a randomised, double-blind, cooparative trial
    • CHANG J, STEWART J, BRUMPT I: Telithromycin treatment of CAP is associated with lower usage of additional RTI-related antibiotics than high-dose amoxycillin in a randomised, double-blind, cooparative trial (abstract no. P418). 11th European Congress of Clinical Microbiology and Infectious Diseases; 2001 Apr 1-4; Istanbul, Turkey (2001).
    • (2001) 11th European Congress of Clinical Microbiology and Infectious Diseases; 2001 Apr 1-4; Istanbul, Turkey
    • Chang, J.1    Stewart, J.2    Brumpt, I.3
  • 137
    • 0037292224 scopus 로고    scopus 로고
    • Efficacy and tolerability of 5-day, once-daily telithromycin compared with 10-day, twice-daily clarithromycin for the treatment of group A beta-hemolytic streptococcal tonsillitis/pharyngitis: A multicenter, randomized, double-blind, parallel-group study
    • QUINN J, RUOFF GE, ZITER PS: Efficacy and tolerability of 5-day, once-daily telithromycin compared with 10-day, twice-daily clarithromycin for the treatment of group A beta-hemolytic streptococcal tonsillitis/pharyngitis: a multicenter, randomized, double-blind, parallel-group study. Clin. Ther. (2003) 25:422-443.
    • (2003) Clin. Ther. , vol.25 , pp. 422-443
    • Quinn, J.1    Ruoff, G.E.2    Ziter, P.S.3
  • 139
    • 0037398758 scopus 로고    scopus 로고
    • Community-acquired respiratory tract infections caused by resistant pneumococci: Clinical and bacteriological efficacy of the ketolide telithromycin
    • FOGARTY CM, KOHNO S, BUCHANAN P, AUBIER M, BAZ M: Community-acquired respiratory tract infections caused by resistant pneumococci: clinical and bacteriological efficacy of the ketolide telithromycin. J. Antimicrob. Chemother. (2003) 51:947-955.
    • (2003) J. Antimicrob. Chemother. , vol.51 , pp. 947-955
    • Fogarty, C.M.1    Kohno, S.2    Buchanan, P.3    Aubier, M.4    Baz, M.5
  • 141
    • 0036014489 scopus 로고    scopus 로고
    • Clinical efficacy of new antibacterial therapies in at-risk populations
    • LORENZ J: Clinical efficacy of new antibacterial therapies in at-risk populations. J. Infect. (2002) 44(Suppl. A):25-30.
    • (2002) J. Infect. , vol.44 , Issue.SUPPL. A , pp. 25-30
    • Lorenz, J.1
  • 142
    • 0000184017 scopus 로고    scopus 로고
    • Design, synthesis and antimicrobial activity of 6-O-substituted ketolides active against resistant respiratory tract pathogens
    • OR YS, CLARK RF, WANG S et al.: Design, synthesis and antimicrobial activity of 6-O-substituted ketolides active against resistant respiratory tract pathogens. J. Med. Chem. (2000) 43:1045-1049.
    • (2000) J. Med. Chem. , vol.43 , pp. 1045-1049
    • Or, Y.S.1    Clark, R.F.2    Wang, S.3
  • 148
    • 0036001190 scopus 로고    scopus 로고
    • Intracellular activity of ABT-773 and other antimicrobial agents against Legionella pneumophila
    • JUNG R, DANZIGER LH, PENDLAND SL: Intracellular activity of ABT-773 and other antimicrobial agents against Legionella pneumophila. J. Antimicrob. Chemother. (2002) 49:857-861.
    • (2002) J. Antimicrob. Chemother. , vol.49 , pp. 857-861
    • Jung, R.1    Danziger, L.H.2    Pendland, S.L.3
  • 149
    • 0036239603 scopus 로고    scopus 로고
    • In vitro bactericidal activity of ABT-773 and amoxicillin against erythromycin-susceptible and -resistant strains of Streptococcus pyogenes
    • PENDLAND SL, NEUHAUSER MM, PRAUSE JL: In vitro bactericidal activity of ABT-773 and amoxicillin against erythromycin-susceptible and -resistant strains of Streptococcus pyogenes. J. Antimicrob. Chemother. (2002) 49:671-674.
    • (2002) J. Antimicrob. Chemother. , vol.49 , pp. 671-674
    • Pendland, S.L.1    Neuhauser, M.M.2    Prause, J.L.3
  • 150
    • 0036844793 scopus 로고    scopus 로고
    • In vitro bactericidal activity of ABT-773 versus four other agents against Streptococcus pneumoniae and Haemophilus influenzae
    • NEUHAUSER MM, JUNG R, DANZIGER LH, PENDLAND SL: In vitro bactericidal activity of ABT-773 versus four other agents against Streptococcus pneumoniae and Haemophilus influenzae. Int. J. Antimicrob. Agents (2002) 20:395-398.
    • (2002) Int. J. Antimicrob. Agents , vol.20 , pp. 395-398
    • Neuhauser, M.M.1    Jung, R.2    Danziger, L.H.3    Pendland, S.L.4
  • 152
  • 156
    • 17944377202 scopus 로고    scopus 로고
    • Efficacies of ABT-773, a new ketolide, against experimental bacterial infections
    • MITTEN MJ, MEULBROEK J, NUKKALA M et al.: Efficacies of ABT-773, a new ketolide, against experimental bacterial infections. Antimicrob. Agents Chemother. (2001) 45:2585-2593.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 2585-2593
    • Mitten, M.J.1    Meulbroek, J.2    Nukkala, M.3
  • 158
    • 0347224303 scopus 로고    scopus 로고
    • Efficacy of ABT-773 (ABT), a new ketolide, versus erythromycin (Ery) against penicillin (Peni)/ery sensitive and macrolide resistant Streptococcus pneumoniae (Sp) in a mouse murine model
    • AZOULAY-DUPUIS E, BEDOS J, MOINE P et al.: Efficacy of ABT-773 (ABT), a new ketolide, versus erythromycin (Ery) against penicillin (Peni)/ery sensitive and macrolide resistant Streptococcus pneumoniae (Sp) in a mouse murine model (abstract no. 1018). 40th Interscience Conference on Antimicrobial Agents and Chemotherapy; 2000 Sept 17-20; Toronto, Canada (2000).
    • (2000) 40th Interscience Conference on Antimicrobial Agents and Chemotherapy; 2000 Sept 17-20; Toronto, Canada
    • Azoulay-Dupuis, E.1    Bedos, J.2    Moine, P.3
  • 161
    • 0036784365 scopus 로고    scopus 로고
    • Bactericidal effect and pharmacodynamics of cethromycin (ABT-773) in a murine pneumococcal pneumonia model
    • KIM MK, ZHOU W, TESSIER PR et al.: Bactericidal effect and pharmacodynamics of cethromycin (ABT-773) in a murine pneumococcal pneumonia model. Antimicrob. Agents Chemother. (2002) 46:3185-3192.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 3185-3192
    • Kim, M.K.1    Zhou, W.2    Tessier, P.R.3
  • 163
    • 0037398792 scopus 로고    scopus 로고
    • Microbiological efficacy of ABT-773 (cethromycin) for the treatment of community-acquired pneumonia due to Chlamydia pneumoniae
    • HAMMERSCHLAG MR, REZNIK T, ROBLIN PM, RAMIREZ J, SUMMERSGILL J, BUKOFZER S: Microbiological efficacy of ABT-773 (cethromycin) for the treatment of community-acquired pneumonia due to Chlamydia pneumoniae. J. Antimicrob. Chemother. (2003) 51:1025-1028.
    • (2003) J. Antimicrob. Chemother. , vol.51 , pp. 1025-1028
    • Hammerschlag, M.R.1    Reznik, T.2    Roblin, P.M.3    Ramirez, J.4    Summersgill, J.5    Bukofzer, S.6
  • 167
    • 0034605212 scopus 로고    scopus 로고
    • Beta-keto-ester chemistry and ketolides. Synthesis and antibacterial activity of 2-halogeno, 2-methyl and 2,3 enol-ether ketolides
    • DENIS A, BRETIN F, FROMENTIN C et al.: Beta-keto-ester chemistry and ketolides. Synthesis and antibacterial activity of 2-halogeno, 2-methyl and 2,3 enol-ether ketolides. Bioorg. Med. Chem. Lett. (2000) 10:2019-2022.
    • (2000) Bioorg. Med. Chem. Lett. , vol.10 , pp. 2019-2022
    • Denis, A.1    Bretin, F.2    Fromentin, C.3
  • 168
    • 0034769815 scopus 로고    scopus 로고
    • Activities of a new fluoroketolide, HMR 3787 and its (des)-fluor derivative RU 64399 compared to those of telithromycin erythromycin A, azithromycin, clarithromycin and clindamycin against macrolide-susceptible or -resistant Streptococcus pneumoniae and S. pyogenes
    • NAGAI K, DAVIES TA, EDNIE LM et al.: Activities of a new fluoroketolide, HMR 3787 and its (des)-fluor derivative RU 64399 compared to those of telithromycin erythromycin A, azithromycin, clarithromycin and clindamycin against macrolide-susceptible or -resistant Streptococcus pneumoniae and S. pyogenes. Antimicrob. Agents Chemother. (2001) 45:3242-3245.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 3242-3245
    • Nagai, K.1    Davies, T.A.2    Ednie, L.M.3
  • 169
    • 12244268677 scopus 로고    scopus 로고
    • Activities of HMR 3787 and RU 64399 compared with those of four other agents against Haemophilus influenzae and Haemophilus parainfluenzae
    • BOZDOGAN B, CLARK C, BRYSKIER A, JACOBS MR, APPELBAUM PC: Activities of HMR 3787 and RU 64399 compared with those of four other agents against Haemophilus influenzae and Haemophilus parainfluenzae. Antimicrob. Agents Chemother. (2003) 47:405-407.
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 405-407
    • Bozdogan, B.1    Clark, C.2    Bryskier, A.3    Jacobs, M.R.4    Appelbaum, P.C.5
  • 172
    • 0034816329 scopus 로고    scopus 로고
    • Cellular uptake of two fluoroketolides, HMR 3562 and HMR 3787, by human polymorphonuclear neutrophils in vitro
    • ABDELGHAFFAR H, VAZIFEH D, LABRO MT: Cellular uptake of two fluoroketolides, HMR 3562 and HMR 3787, by human polymorphonuclear neutrophils in vitro. Antimicrob. Agents Chemother. (2001) 45:2798-2806.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 2798-2806
    • Abdelghaffar, H.1    Vazifeh, D.2    Labro, M.T.3
  • 173
    • 0034824275 scopus 로고    scopus 로고
    • Synthesis and antibacterial activity of the tricyclic ketolides TE-802 and its analogs
    • KASHIMURA M, ASAKA T, MISAWA Y, MATSUMOTO K, MORIMOTO S: Synthesis and antibacterial activity of the tricyclic ketolides TE-802 and its analogs. J. Antibiot. (Tokyo) (2001) 54:664-678.
    • (2001) J. Antibiot. (Tokyo) , vol.54 , pp. 664-678
    • Kashimura, M.1    Asaka, T.2    Misawa, Y.3    Matsumoto, K.4    Morimoto, S.5
  • 174
    • 0037797390 scopus 로고    scopus 로고
    • Recent developments in macrolide antimicrobial research
    • ASAKA T, MANAKA A, SUGIYAMA H: Recent developments in macrolide antimicrobial research. Curr. Top. Med. Chem (2003) 3:961-989.
    • (2003) Curr. Top. Med. Chem. , vol.3 , pp. 961-989
    • Asaka, T.1    Manaka, A.2    Sugiyama, H.3
  • 175
    • 0037624824 scopus 로고    scopus 로고
    • Synthesis of 9-oxime-11,12-carbamate ketolides Through a novel N-deamination reaction of 11,12-hydrazonocarbamate ketolide
    • DENIS A, PEJAC JM, BRETIN F, BONNEFOY A: Synthesis of 9-oxime-11,12-carbamate ketolides Through a novel N-deamination reaction of 11,12-hydrazonocarbamate ketolide. Bioorg. Med. Chem. (2003) 11:2389-2394.
    • (2003) Bioorg. Med. Chem. , vol.11 , pp. 2389-2394
    • Denis, A.1    Pejac, J.M.2    Bretin, F.3    Bonnefoy, A.4
  • 177
    • 0038416843 scopus 로고    scopus 로고
    • Synthesis and antibacterial activity of 6-O-arylbutynyl ketolides with improved activity against some key erythromycin-resistant pathogens
    • KEYES RF, CARTER JJ, ENGLUND EE et al.: Synthesis and antibacterial activity of 6-O-arylbutynyl ketolides with improved activity against some key erythromycin-resistant pathogens. J. Med. Chem. (2003) 46:1795-1798.
    • (2003) J. Med. Chem. , vol.46 , pp. 1795-1798
    • Keyes, R.F.1    Carter, J.J.2    Englund, E.E.3
  • 178
    • 0028858324 scopus 로고
    • In vivo evaluation of three acid-stable azalide compounds, L-701,677, L-708,299 and L-708,365 compared to erythromycin, azithromycin and clarithromycin
    • GILL C, ABRUZZO GK, FLATTERY AM et al.: In vivo evaluation of three acid-stable azalide compounds, L-701,677, L-708,299 and L-708,365 compared to erythromycin, azithromycin and clarithromycin. J. Antibiot. (Tokyo) (1995) 48(10):1141-1147.
    • (1995) J. Antibiot. (Tokyo) , vol.48 , Issue.10 , pp. 1141-1147
    • Gill, C.1    Abruzzo, G.K.2    Flattery, A.M.3
  • 179
    • 0036247950 scopus 로고    scopus 로고
    • Synthesis and in vitro antimicrobial activity of 3-keto 16-membered macrolides derived from tylosin
    • CREEMER LC, TOTH JE, KIRST HA: Synthesis and in vitro antimicrobial activity of 3-keto 16-membered macrolides derived from tylosin. J. Antibiot. (Tokyo) (2002) 55:427-436.
    • (2002) J. Antibiot. (Tokyo) , vol.55 , pp. 427-436
    • Creemer, L.C.1    Toth, J.E.2    Kirst, H.A.3
  • 180
    • 0034752380 scopus 로고    scopus 로고
    • Overcoming antimicrobial resistance: Profile of a new ketolide antibacterial, telithromycin
    • LECLERCQ R: Overcoming antimicrobial resistance: profile of a new ketolide antibacterial, telithromycin. J. Antimicrob. Chemother. (2001) 48(Suppl. T1):9-23.
    • (2001) J. Antimicrob. Chemother. , vol.48 , Issue.SUPPL. T1 , pp. 9-23
    • Leclercq, R.1
  • 182
    • 0033958240 scopus 로고    scopus 로고
    • In vitro development of resistance to telithromycin (HMR 3647), four macrolides, clindamycin and pristinamycin in Streptococcus pneumoniae
    • DAVIES T, DEWASSE B, JACOBS MR, APPELBAUM PC: In vitro development of resistance to telithromycin (HMR 3647), four macrolides, clindamycin and pristinamycin in Streptococcus pneumoniae. Antimicrob. Agents Chemother. (2000) 44:414-417.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 414-417
    • Davies, T.1    Dewasse, B.2    Jacobs, M.R.3    Appelbaum, P.C.4
  • 183
    • 0036001183 scopus 로고    scopus 로고
    • Comparison of selection for mutants with reduced susceptibility to ABT-773, erythromycin and rifampicin in respiratory tract pathogens
    • NILIUS AM, HENSEY-RUDLOFF DM, REIMANN MA, FLAMM RK: Comparison of selection for mutants with reduced susceptibility to ABT-773, erythromycin and rifampicin in respiratory tract pathogens. J. Antimicrob. Chemother. (2002) 49:831-836.
    • (2002) J. Antimicrob. Chemother. , vol.49 , pp. 831-836
    • Nilius, A.M.1    Hensey-Rudloff, D.M.2    Reimann, M.A.3    Flamm, R.K.4
  • 184
    • 0036014487 scopus 로고    scopus 로고
    • Will resistance to ketolides develop in Streptococcus pneumoniae?
    • LECLERCQ R: Will resistance to ketolides develop in Streptococcus pneumoniae? J. Infect. (2002) 44(Suppl. A): 11-16.
    • (2002) J. Infect. , vol.44 , Issue.SUPPL. A , pp. 11-16
    • Leclercq, R.1


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