메뉴 건너뛰기




Volumn 36, Issue 1, 2000, Pages 183-193

Macrolide-ketolide inhibition of MLS-resistant ribosomes is improved by alternative drug interaction with domain II of 23S rRNA

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL RNA; CLARITHROMYCIN; ERYTHROMYCIN; HMR 3004; KETOLIDE; MACROLIDE; RIBOSOME DNA; RIBOSOME RNA; RU 56006; RU 66252; TELITHROMYCIN; UNCLASSIFIED DRUG;

EID: 0034115717     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2000.01841.x     Document Type: Article
Times cited : (173)

References (46)
  • 1
    • 0026321132 scopus 로고
    • Specific structural probing of plasmid-coded ribosomal RNAs from Escherichia coli
    • Aagaard, C., Rosendahl, G., Dam, M., Powers, T., and Douthwaite, S. (1991) Specific structural probing of plasmid-coded ribosomal RNAs from Escherichia coli. Biochimie 73: 1439-1444.
    • (1991) Biochimie , vol.73 , pp. 1439-1444
    • Aagaard, C.1    Rosendahl, G.2    Dam, M.3    Powers, T.4    Douthwaite, S.5
  • 3
    • 0030827227 scopus 로고    scopus 로고
    • Antibacterial activity of RU 64004 (HMR 3004), a novel ketolide derivative active against respiratory pathogens
    • Agouridas, C., Bonnefoy, A., and Chantot, J.F. (1997b) Antibacterial activity of RU 64004 (HMR 3004), a novel ketolide derivative active against respiratory pathogens. Antimicrob Agents Chemother 41: 2149-2158.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 2149-2158
    • Agouridas, C.1    Bonnefoy, A.2    Chantot, J.F.3
  • 5
    • 0033607003 scopus 로고    scopus 로고
    • Placement of protein and RNA structures into a 5Ȧ-resolution map of the 50S ribosomal subunit
    • Ban, N., Nissen, P., Hansen, J., Capel, M., Moore, P.B., and Steitz, T.A. (1999) Placement of protein and RNA structures into a 5Ȧ-resolution map of the 50S ribosomal subunit. Nature 400: 841-847.
    • (1999) Nature , vol.400 , pp. 841-847
    • Ban, N.1    Nissen, P.2    Hansen, J.3    Capel, M.4    Moore, P.B.5    Steitz, T.A.6
  • 8
    • 0019358924 scopus 로고
    • Construction and fine mapping of recombinant plasmids containing the rrnB ribosomal RNA operon of E. coli
    • Brosius, J., Ullrich, A., Raker, M.A., Gray, A., Dull, T.J., Gutell, R.R., and Noller, H.F. (1981) Construction and fine mapping of recombinant plasmids containing the rrnB ribosomal RNA operon of E. coli. Plasmid 6: 112-118.
    • (1981) Plasmid , vol.6 , pp. 112-118
    • Brosius, J.1    Ullrich, A.2    Raker, M.A.3    Gray, A.4    Dull, T.J.5    Gutell, R.R.6    Noller, H.F.7
  • 9
  • 10
    • 0003053221 scopus 로고
    • Antibiotic probes of Escherichia coli peptidyltransferase
    • Hill, W., Dahlberg, A., Garrett, R.A., Moore, P.B., Schlessinger, D., and Warner, J. (eds). Washington, DC: American Society for Microbiology
    • Cooperman, B.S., Weitzmann, C.J., and Fernández, C.L. (1990) Antibiotic probes of Escherichia coli peptidyltransferase. In The Structure, Function, and Evolution of Ribosomes. Hill, W., Dahlberg, A., Garrett, R.A., Moore, P.B., Schlessinger, D., and Warner, J. (eds). Washington, DC: American Society for Microbiology, pp. 491-501.
    • (1990) The Structure, Function, and Evolution of Ribosomes , pp. 491-501
    • Cooperman, B.S.1    Weitzmann, C.J.2    Fernández, C.L.3
  • 11
    • 0026601409 scopus 로고
    • Functional interactions within 23S rRNA involving the peptidyltransferase center
    • Douthwaite, S. (1992) Functional interactions within 23S rRNA involving the peptidyltransferase center. J Bacteriol 174: 1333-1338.
    • (1992) J Bacteriol , vol.174 , pp. 1333-1338
    • Douthwaite, S.1
  • 12
    • 0027248565 scopus 로고
    • Erythromycin binding is reduced in ribosomes with conformational alterations in the 23S rRNA peptidyl transferase loop
    • Douthwaite, S., and Aagaard, C. (1993) Erythromycin binding is reduced in ribosomes with conformational alterations in the 23S rRNA peptidyl transferase loop. J Mol Biol 232: 725-731.
    • (1993) J Mol Biol , vol.232 , pp. 725-731
    • Douthwaite, S.1    Aagaard, C.2
  • 13
    • 0024388825 scopus 로고
    • Defining the structural requirements for a helix in 23S ribosomal RNA that confers erythromycin resistance
    • Douthwaite, S., Powers, T., Lee, J.Y., and Noller, H.F. (1989) Defining the structural requirements for a helix in 23S ribosomal RNA that confers erythromycin resistance. J Mol Biol 209: 655-665.
    • (1989) J Mol Biol , vol.209 , pp. 655-665
    • Douthwaite, S.1    Powers, T.2    Lee, J.Y.3    Noller, H.F.4
  • 14
    • 0030956596 scopus 로고    scopus 로고
    • Susceptibilities of 228 penicillin- and erythromycin-susceptible and -resistant pneumococci to RU 64004 (HMR 3004), a new ketolide, compared with susceptibilities to 16 other agents
    • Ednie, L.M., Spangler, S.K., Jacobs, M.R., and Appelbaum, P.C. (1997) Susceptibilities of 228 penicillin-and erythromycin-susceptible and -resistant pneumococci to RU 64004 (HMR 3004), a new ketolide, compared with susceptibilities to 16 other agents. Antimicrob Agents Chemother 41: 1033-1036.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 1033-1036
    • Ednie, L.M.1    Spangler, S.K.2    Jacobs, M.R.3    Appelbaum, P.C.4
  • 15
    • 0031552163 scopus 로고    scopus 로고
    • Novel 3-deoxy-3-descladinosyl-6-O-methyl erythromycin A analogues. Synthesis and in vitro activity
    • Elliot, R.L., Poreh, D., Nilius, A.M., Johnson, P.M., Flamm, R.K., Chu, D.T.W., et al. (1997) Novel 3-deoxy-3-descladinosyl-6-O-methyl erythromycin A analogues. Synthesis and in vitro activity. Biorg Med Chem Letters 7: 641-646.
    • (1997) Biorg Med Chem Letters , vol.7 , pp. 641-646
    • Elliot, R.L.1    Poreh, D.2    Nilius, A.M.3    Johnson, P.M.4    Flamm, R.K.5    Chu, D.T.W.6
  • 16
    • 0021888455 scopus 로고
    • Chloramphenicol-erythromycin resistance mutations in a 23S rRNA gene of Escherichia coli
    • Ettayebi, M., Prasad, S., and Morgan, E.A. (1985) Chloramphenicol-erythromycin resistance mutations in a 23S rRNA gene of Escherichia coli. J Bacteriol 162: 551-557.
    • (1985) J Bacteriol , vol.162 , pp. 551-557
    • Ettayebi, M.1    Prasad, S.2    Morgan, E.A.3
  • 18
    • 0024320137 scopus 로고
    • Binding of novel macrolide structures to macrolide-lincosamides-streptogramin B-resistant ribosomes inhibits protein synthesis and bacterial growth
    • Goldman, R.C., and Kadam, S.K. (1989) Binding of novel macrolide structures to macrolide-lincosamides-streptogramin B-resistant ribosomes inhibits protein synthesis and bacterial growth. Antimicrob Agents Chemother 33: 1058-1066.
    • (1989) Antimicrob Agents Chemother , vol.33 , pp. 1058-1066
    • Goldman, R.C.1    Kadam, S.K.2
  • 19
    • 0029971085 scopus 로고    scopus 로고
    • 3-keto-11,12-carbazate derivatives of 6-O-methylerythromycin A. Synthesis and in vitro activity
    • Griesgraber, G., Or, Y.S., Chu, D.T.W., Nilius, A.M., Johnson, P.M., Flamm, R.K., et al. (1996) 3-keto-11,12-carbazate derivatives of 6-O-methylerythromycin A. Synthesis and in vitro activity. J Antibot 49: 465-477.
    • (1996) J Antibot , vol.49 , pp. 465-477
    • Griesgraber, G.1    Or, Y.S.2    Chu, D.T.W.3    Nilius, A.M.4    Johnson, P.M.5    Flamm, R.K.6
  • 20
    • 0028261409 scopus 로고
    • Lessons from an evolving rRNA: 16S and 23S rRNA structures from a comparative perspective
    • Gutell, R.R., Larsen, N., and Woese, C.R. (1994) Lessons from an evolving rRNA: 16S and 23S rRNA structures from a comparative perspective. Microbiol Rev 58: 10-26.
    • (1994) Microbiol Rev , vol.58 , pp. 10-26
    • Gutell, R.R.1    Larsen, N.2    Woese, C.R.3
  • 21
    • 0032950956 scopus 로고    scopus 로고
    • The macrolide-ketolide antibiotic binding site is formed by structures in domains II and V of 23S ribosomal RNA
    • Hansen, L.H., Mauvais, P., and Douthwaite, S. (1999) The macrolide-ketolide antibiotic binding site is formed by structures in domains II and V of 23S ribosomal RNA. Mol Microbiol 31: 623-632.
    • (1999) Mol Microbiol , vol.31 , pp. 623-632
    • Hansen, L.H.1    Mauvais, P.2    Douthwaite, S.3
  • 22
    • 0030725251 scopus 로고    scopus 로고
    • Macrolide resistance in Helicobacter pylori: Mechanism and stability in strains from clarithromycin-treated patients
    • Hultén, K., Gibreel, A., Sköld, O., and Engstrand, L. (1997) Macrolide resistance in Helicobacter pylori: Mechanism and stability in strains from clarithromycin-treated patients. Antimicrob Agents Chemother 41: 2550-2553.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 2550-2553
    • Hultén, K.1    Gibreel, A.2    Sköld, O.3    Engstrand, L.4
  • 23
    • 0031053885 scopus 로고    scopus 로고
    • In vitro evaluation of a novel ketolide antimicrobial agent, RU 64004
    • Jamjian, C., Biedenback, D.J., and Jones, R. (1997) In vitro evaluation of a novel ketolide antimicrobial agent, RU 64004. Antimicrob Agents Chemother 41: 454-459.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 454-459
    • Jamjian, C.1    Biedenback, D.J.2    Jones, R.3
  • 24
    • 0023604799 scopus 로고
    • Chloramphenicol, erythromycin, carbomycin and vernamycin B protect overlapping sites in the peptidyl transferase region of 23S ribosomal RNA
    • Moazed, D., and Noller, H.F. (1987) Chloramphenicol, erythromycin, carbomycin and vernamycin B protect overlapping sites in the peptidyl transferase region of 23S ribosomal RNA. Biochimie 69: 879-884.
    • (1987) Biochimie , vol.69 , pp. 879-884
    • Moazed, D.1    Noller, H.F.2
  • 25
    • 0028800955 scopus 로고
    • Genetic basis of macrolide resistance in Mycobacterium avium isolated from patients with disseminated disease
    • Nash, K.A., and Inderlied, C.B. (1995) Genetic basis of macrolide resistance in Mycobacterium avium isolated from patients with disseminated disease. Antimicrob Agents Chemother 39: 2625-2630.
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 2625-2630
    • Nash, K.A.1    Inderlied, C.B.2
  • 26
    • 0021158357 scopus 로고
    • Structure of ribosomal RNA
    • Noller, H.F. (1984) Structure of ribosomal RNA. Ann Rev Biochem 53: 119-162.
    • (1984) Ann Rev Biochem , vol.53 , pp. 119-162
    • Noller, H.F.1
  • 27
    • 0030834006 scopus 로고    scopus 로고
    • Macrolide resistance in Helicobacter pylori: Rapid detection of point mutations and assays of macrolide binding to ribosomes
    • Occhialini, A., Urdaci, M., Doucet-Populaire, F., Bébéar, C.M., Lamouliatte, H., and Mégraud, F. (1997) Macrolide resistance in Helicobacter pylori: Rapid detection of point mutations and assays of macrolide binding to ribosomes. Antimicrob Agents Chemother 41: 2724-2728.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 2724-2728
    • Occhialini, A.1    Urdaci, M.2    Doucet-Populaire, F.3    Bébéar, C.M.4    Lamouliatte, H.5    Mégraud, F.6
  • 29
    • 0033582599 scopus 로고    scopus 로고
    • Sites of interaction of streptogramin A and B antibiotics in the peptidyl transferase loop of 23S rRNA and the synergism of their inhibitory mechanisms
    • Porse, B., and Garrett, R.A. (1999) Sites of interaction of streptogramin A and B antibiotics in the peptidyl transferase loop of 23S rRNA and the synergism of their inhibitory mechanisms. J Mol Biol 286: 375-387.
    • (1999) J Mol Biol , vol.286 , pp. 375-387
    • Porse, B.1    Garrett, R.A.2
  • 30
    • 0028924641 scopus 로고
    • Fine structure of the peptidyl transferase centre on 23S-like rRNAs deduced from chemical probing of antibiotic-ribosome complexes
    • Rodriguez-Fonseca, C., Amils, R., and Garrett, R.A. (1995) Fine structure of the peptidyl transferase centre on 23S-like rRNAs deduced from chemical probing of antibiotic-ribosome complexes. J Mol Biol 247: 224-235.
    • (1995) J Mol Biol , vol.247 , pp. 224-235
    • Rodriguez-Fonseca, C.1    Amils, R.2    Garrett, R.A.3
  • 31
    • 0031002046 scopus 로고    scopus 로고
    • Clinical resistance to erythromycin and clindamycin in cutaneous propionibacteria isolated from acne patients is associated with mutations in 23S rRNA
    • Ross, J.I., Eady, E.A., Cove, J.H., Jones, C.E., Ratyal, A.M., Miller, Y.W. et al. (1997) Clinical resistance to erythromycin and clindamycin in cutaneous propionibacteria isolated from acne patients is associated with mutations in 23S rRNA. Antimicrob Agents Chemother 41: 1162-1165.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 1162-1165
    • Ross, J.I.1    Eady, E.A.2    Cove, J.H.3    Jones, C.E.4    Ratyal, A.M.5    Miller, Y.W.6
  • 34
    • 0343742636 scopus 로고    scopus 로고
    • In vitro activity of RU 64004 (HMR 3004), a new ketolide antibiotic, against Gram-positive bacteria
    • Schülin, T., Wennersten, C.B., Moellering, R.C., and Eliopoulos, G.M. (1997) In vitro activity of RU 64004 (HMR 3004), a new ketolide antibiotic, against Gram-positive bacteria. Antimicrob Agents Chemother 41: 1192-1202.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 1192-1202
    • Schülin, T.1    Wennersten, C.B.2    Moellering, R.C.3    Eliopoulos, G.M.4
  • 35
    • 0024271795 scopus 로고
    • Antibiotic resistance mutations in ribosomal RNA genes of Escherichia coli
    • Sigmund, C.D., Ettayebi, M., Borden, A., and Morgan, E.A. (1988) Antibiotic resistance mutations in ribosomal RNA genes of Escherichia coli. Methods Enzymol 164: 673-690.
    • (1988) Methods Enzymol , vol.164 , pp. 673-690
    • Sigmund, C.D.1    Ettayebi, M.2    Borden, A.3    Morgan, E.A.4
  • 36
    • 0021064473 scopus 로고
    • Site of action of a ribosomal RNA methylase responsible for resistance to erythromycin and other antibiotics
    • Skinner, R.H., Cundliffe, E., and Schmidt, F.J. (1983) Site of action of a ribosomal RNA methylase responsible for resistance to erythromycin and other antibiotics. J Biol Chem 258: 12702-12706.
    • (1983) J Biol Chem , vol.258 , pp. 12702-12706
    • Skinner, R.H.1    Cundliffe, E.2    Schmidt, F.J.3
  • 37
    • 0024241761 scopus 로고
    • Structural analysis of RNA using chemical and enzymatic probing monitored by primer extension
    • Stern, S., Moazed, D., and Noller, H.F. (1988) Structural analysis of RNA using chemical and enzymatic probing monitored by primer extension. Methods Enzymol 164: 481-489.
    • (1988) Methods Enzymol , vol.164 , pp. 481-489
    • Stern, S.1    Moazed, D.2    Noller, H.F.3
  • 38
    • 0026656308 scopus 로고
    • Identification of a single base change in ribosomal RNA leading to erythromycin resistance
    • Vannuffel, P., Giambattista, M.D., Morgan, E.A., and Cocito, C. (1992) Identification of a single base change in ribosomal RNA leading to erythromycin resistance. J Biol Chem 267: 8377-8382.
    • (1992) J Biol Chem , vol.267 , pp. 8377-8382
    • Vannuffel, P.1    Giambattista, M.D.2    Morgan, E.A.3    Cocito, C.4
  • 40
    • 0030770494 scopus 로고    scopus 로고
    • Point mutations in the 23S rRNA gene of Helicobacter pylori associated with different levels of clarithromycin resistance
    • Versalovic, J., Osato, M.S., Spakovsky, K., Dore, M.P., Reddy, R., Stone, G.G., et al. (1997) Point mutations in the 23S rRNA gene of Helicobacter pylori associated with different levels of clarithromycin resistance. J Antimicrob Chemother 40: 283-286.
    • (1997) J Antimicrob Chemother , vol.40 , pp. 283-286
    • Versalovic, J.1    Osato, M.S.2    Spakovsky, K.3    Dore, M.P.4    Reddy, R.5    Stone, G.G.6
  • 41
    • 0023587832 scopus 로고
    • A plasmid-coded and site-directed mutation in Escherichia coli 23S RNA that confers resistance to erythromycin: Implications for the mechanism of action of erythromycin
    • Vester, B., and Garrett, R.A. (1987) A plasmid-coded and site-directed mutation in Escherichia coli 23S RNA that confers resistance to erythromycin: Implications for the mechanism of action of erythromycin. Biochimie 69: 891-900.
    • (1987) Biochimie , vol.69 , pp. 891-900
    • Vester, B.1    Garrett, R.A.2
  • 42
    • 0029330769 scopus 로고
    • The conformation of 23S rRNA nucleotide A2058 determines its recognition by the ErmE methyltransferase
    • Vester, B., Hansen, L.H., and Douthwaite, S. (1995) The conformation of 23S rRNA nucleotide A2058 determines its recognition by the ErmE methyltransferase. RNA 1: 501-509.
    • (1995) RNA , vol.1 , pp. 501-509
    • Vester, B.1    Hansen, L.H.2    Douthwaite, S.3
  • 43
    • 8944228464 scopus 로고    scopus 로고
    • Genetic basis for clarithromycin resistance among isolates of Mycobacterium chelonae and Mycobacterium abscessus
    • Wallace, R.J. Jr, Meier, A., Brown, B.A., Zhang, Y., Sander, P., Onyi, G.O., et al. (1996) Genetic basis for clarithromycin resistance among isolates of Mycobacterium chelonae and Mycobacterium abscessus. Antimicrob Agents Chemother 40: 1676-1681.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 1676-1681
    • Wallace R.J., Jr.1    Meier, A.2    Brown, B.A.3    Zhang, Y.4    Sander, P.5    Onyi, G.O.6
  • 44
    • 0031879814 scopus 로고    scopus 로고
    • Site-specific mutations in the 23S rRNA gene of Helicobacter pylori confer two types of resistance to macrolide-lincosamide-streptogramin B antibiotics
    • Wang, G., and Taylor, D.E. (1998) Site-specific mutations in the 23S rRNA gene of Helicobacter pylori confer two types of resistance to macrolide-lincosamide-streptogramin B antibiotics. Antimicrob Agents Chemother 42: 1952-1958.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 1952-1958
    • Wang, G.1    Taylor, D.E.2
  • 45
    • 0028963496 scopus 로고
    • Erythromycin resistance by ribosome modification
    • Weisblum, B. (1995) Erythromycin resistance by ribosome modification. Antimicrob Agents Chemother 39: 577-585.
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 577-585
    • Weisblum, B.1
  • 46
    • 0032904341 scopus 로고    scopus 로고
    • Ketolide resistance mutation in domain II of 23S rRNA reveals rRNA folding required for formation of macrolide-binding site
    • Xiong, L., Shah, S., Mauvais, P., and Mankin, A.S. (1999) Ketolide resistance mutation in domain II of 23S rRNA reveals rRNA folding required for formation of macrolide-binding site. Mol Microbiol 31: 633-639.
    • (1999) Mol Microbiol , vol.31 , pp. 633-639
    • Xiong, L.1    Shah, S.2    Mauvais, P.3    Mankin, A.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.