In vitro activity of the novel ketolide HMR 3647 and comparative oral antibiotics against Canadian respiratory tract isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis

Diagnostic Microbiology and Infectious Disease

Volumn 35, Issue 1, 1999, Pages 37-44

  Hoban, Daryl J ^a,b   Zhanel, George G ^a   Karlowsky, James A ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b HEALTH SCIENCES CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; AZITHROMYCIN; CEFACLOR; CEFUROXIME; CIPROFLOXACIN; CLARITHROMYCIN; CLINDAMYCIN; COTRIMOXAZOLE; ERYTHROMYCIN; ERYTHRONOLIDE A; LEVOFLOXACIN; PENICILLIN G; ROXITHROMYCIN; TELITHROMYCIN; TETRACYCLINE;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; HAEMOPHILUS INFLUENZAE; HUMAN; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; MORAXELLA CATARRHALIS; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; STREPTOCOCCUS PNEUMONIAE;

ADMINISTRATION, ORAL; ANTI-BACTERIAL AGENTS; CANADA; HAEMOPHILUS INFECTIONS; HAEMOPHILUS INFLUENZAE; HUMANS; KETOLIDES; MACROLIDES; MICROBIAL SENSITIVITY TESTS; MORAXELLA (BRANHAMELLA) CATARRHALIS; NEISSERIACEAE INFECTIONS; RESPIRATORY TRACT INFECTIONS; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS PNEUMONIAE;

EID: 0033198896     PISSN: 07328893     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0732-8893(99)00053-X     Document Type: Article

References (11)

1. Barry A.L., Fuchs P.C., Brown S.D. Antipneumococcal activity of a ketolide (HMR 3647), a streptogramin (quinupristin/dalfopristin), a macrolide (erythromycin), and a lincosamide (clindamycin). Antimicrob Agents Chemother. 42:1997;945-946.
2. Barry A.L., Fuchs P.C., Brown S.D. In vitro activities of the ketolide HMR 3647 against recent Gram-positive clinical isolates and Haemophilus influenzae. Antimicrob Agents Chemother. 42:1998;2138-2140.
3. Bebear C.M., Renaudin H., Aydin M.D., Chantin J.F., Bebear C. In vitro activity of ketolides against mycoplasmas. J Antimicrob Chemother. 39:1997;669-670.
4. B resistance phenotype. J Antimicrob Chemother. 40:1997;85-90.
5. Bryskier A., Agouridas C., Chantot J.F. Ketolides New semisynthetic 14-membered-ring macrolides . Zinner S.H., Young L.S., Acar J.F., Neu H.C. Expanding Indications for the New Macrolides, Azalides and Streptogramins. 1997;39-50 Marcel Dekker, New York.
6. Doern G.V., Brueggemann A., Holley H.P., Rauch A.M. Antimicrobial resistance of Streptococcus pneumoniae recovered from outpatients in the United States during the winter months of 1994 to 1995 Results of a 30-center national surveillance study . Antimicrob Agents Chemother. 40:1996;1208-1213.
7. Hamilton-Miller J.M.T., Shah S. Comparative in vitro activity of ketolide HMR 3647 and four macrolides against Gram-positive cocci of known erythromycin susceptibility status. J Antimicrob Chemother. 41:1998;649-653.
8. Jones R.N., Biedenbach D.J. Antimicrobial activity of RU-66647, a new ketolide. Diagn Microbiol Infect Dis. 27:1997;7-12.
9. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically. Approved Standard M7-A4. 4th ed. 1997;National Committee for Clinical Laboratory Standards, Wayne, PA.
10. Performance Standards for Antimicrobial Susceptibility Testing; Ninth Informational Supplement. M100-S9. 1999;National Committee for Clinical Laboratory Standards, Wayne, PA.
11. Pankuch G.A., Visalli M.A., Jacobs M.R., Applebaum P.C. Susceptibilities of penicillin- and erythromycin-susceptible and -resistant pneumococci to HMR 3647 (RU 66647), a new ketolide, compared with susceptibilities to 17 other agents. Antimicrob Agents Chemother. 42:1998;624-630.