-
1
-
-
0023959725
-
Proopiomelanocortin processing in the pituitary, central nervous system, and peripheral tissues
-
Smith, A. I. & Funder, J. W. Proopiomelanocortin processing in the pituitary, central nervous system, and peripheral tissues. Endocr. Rev. 9, 159-179 (1988).
-
(1988)
Endocr. Rev.
, vol.9
, pp. 159-179
-
-
Smith, A.I.1
Funder, J.W.2
-
2
-
-
0036262319
-
Proteinase-activated receptors
-
International Union of Pharmacology. XXVIII
-
Hollenberg, M. D. & Compton, S. J. International Union of Pharmacology. XXVIII. Proteinase-activated receptors. Pharmacol. Rev. 54, 203-217 (2002).
-
(2002)
Pharmacol. Rev.
, vol.54
, pp. 203-217
-
-
Hollenberg, M.D.1
Compton, S.J.2
-
3
-
-
0026035523
-
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
-
Vu, T. K., Hung, D. T., Wheaton, V. I. & Coughlin, S. R. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64, 1057-1068 (1991). Cloning of the first member of the PAR family, showing its activation by thrombin and by a peptide resembling the N terminus generated by thrombin.
-
(1991)
Cell
, vol.64
, pp. 1057-1068
-
-
Vu, T.K.1
Hung, D.T.2
Wheaton, V.I.3
Coughlin, S.R.4
-
4
-
-
0041317074
-
Proteinase-activated receptor activation by coagulation proteinases
-
Riewald, M. & Ruf, W. Proteinase-activated receptor activation by coagulation proteinases. Drug Dev. Res. 59, 400-407 (2003).
-
(2003)
Drug Dev. Res.
, vol.59
, pp. 400-407
-
-
Riewald, M.1
Ruf, W.2
-
5
-
-
0030979972
-
Protease-activated receptor 3 is a second thrombin receptor in humans
-
Ishihara, H. et al. Protease-activated receptor 3 is a second thrombin receptor in humans. Nature 386, 502-506 (1997).
-
(1997)
Nature
, vol.386
, pp. 502-506
-
-
Ishihara, H.1
-
6
-
-
0032499696
-
Cloning and characterization of human protease-activated receptor 4
-
Xu, W. F. et al. Cloning and characterization of human protease-activated receptor 4. Proc. Natl Acad. Sci. USA 95, 6642-6646 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6642-6646
-
-
Xu, W.F.1
-
7
-
-
0027933068
-
Molecular cloning of a potential proteinase activated receptor
-
Nystedt, S., Emilsson, K., Wahlestedt, C. & Sundelin, J. Molecular cloning of a potential proteinase activated receptor. Proc. Natl Acad. Sci. USA 91, 9208-9212 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9208-9212
-
-
Nystedt, S.1
Emilsson, K.2
Wahlestedt, C.3
Sundelin, J.4
-
8
-
-
0028934047
-
The mouse proteinase-activated receptor-2 cDNA and gene. Molecular cloning and functional expression
-
Nystedt, S., Larsson, A. K., Aberg, H. & Sundelin, J. The mouse proteinase-activated receptor-2 cDNA and gene. Molecular cloning and functional expression. J. Biol. Chem. 270, 5950-5955 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 5950-5955
-
-
Nystedt, S.1
Larsson, A.K.2
Aberg, H.3
Sundelin, J.4
-
9
-
-
15444346942
-
Interactions of mast cell tryptase with thrombin receptors and PAR-2
-
Molino, M. et al. Interactions of mast cell tryptase with thrombin receptors and PAR-2. J. Biol. Chem. 272, 4043-4049 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 4043-4049
-
-
Molino, M.1
-
10
-
-
0026072517
-
Domains specifying thrombin-receptor interaction
-
Vu, T. K., Wheaton, V. I., Hung, D. T., Charo, I. & Coughlin, S. R. Domains specifying thrombin-receptor interaction. Nature 353, 674-677 (1991). Definition of PAR1 cleavage as the receptor-activating mechanism.
-
(1991)
Nature
, vol.353
, pp. 674-677
-
-
Vu, T.K.1
Wheaton, V.I.2
Hung, D.T.3
Charo, I.4
Coughlin, S.R.5
-
11
-
-
0028850759
-
+ exchange by a thrombin receptor antagonist
-
+ exchange by a thrombin receptor antagonist. Biochem. Pharmacol. 49, 519-528 (1995).
-
(1995)
Biochem. Pharmacol.
, vol.49
, pp. 519-528
-
-
Seiler, S.M.1
-
12
-
-
0013588997
-
Protease-activated receptor genes are clustered on 5q13
-
Guyonnet Duperat, V., Jacquelin, B., Boisseau, P., Arveiler, B. & Nurden, A. T. Protease-activated receptor genes are clustered on 5q13. Blood 92, 25-31 (1998).
-
(1998)
Blood
, vol.92
, pp. 25-31
-
-
Guyonnet Duperat, V.1
Jacquelin, B.2
Boisseau, P.3
Arveiler, B.4
Nurden, A.T.5
-
13
-
-
0031744875
-
Proteinase-activated receptors: Novel mechanisms of signaling by serine proteases
-
Dery, O., Corvera, C. U., Steinhoff, M. & Bunnett, N. W. Proteinase-activated receptors: novel mechanisms of signaling by serine proteases. Am. J. Physiol. 274, C1429-C1452 (1998).
-
(1998)
Am. J. Physiol.
, vol.274
-
-
Dery, O.1
Corvera, C.U.2
Steinhoff, M.3
Bunnett, N.W.4
-
14
-
-
0037491754
-
Protease-activated receptor subtype expression in developing eye and adult retina of the rat after optic nerve crush
-
Rohatgi, T., Sedehizade, F., Sabel, B. A. & Reiser, G. Protease-activated receptor subtype expression in developing eye and adult retina of the rat after optic nerve crush. J. Neurosci. Res. 73, 246-254 (2003).
-
(2003)
J. Neurosci. Res.
, vol.73
, pp. 246-254
-
-
Rohatgi, T.1
Sedehizade, F.2
Sabel, B.A.3
Reiser, G.4
-
15
-
-
0029113121
-
Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2
-
Nystedt, S., Emilsson, K., Larsson, A. K., Strombeck, B. & Sundelin, J. Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2. Eur. J. Biochem. 232, 84-89 (1995).
-
(1995)
Eur. J. Biochem.
, vol.232
, pp. 84-89
-
-
Nystedt, S.1
Emilsson, K.2
Larsson, A.K.3
Strombeck, B.4
Sundelin, J.5
-
16
-
-
0030008312
-
Role of the thrombin receptor in development and evidence for a second receptor
-
Connolly, A. J., Ishihara, H., Kahn, M. L., Farese, R. V. Jr & Coughlin, S. R. Role of the thrombin receptor in development and evidence for a second receptor. Nature 381, 516-519 (1996).
-
(1996)
Nature
, vol.381
, pp. 516-519
-
-
Connolly, A.J.1
Ishihara, H.2
Kahn, M.L.3
Farese Jr., R.V.4
Coughlin, S.R.5
-
17
-
-
0032510949
-
The human proteinase-activated receptor-3 (PAR-3) gene. Identification within a Par gene cluster and characterization in vascular endothelial cells and platelets
-
Schmidt, V. A. et al. The human proteinase-activated receptor-3 (PAR-3) gene. Identification within a Par gene cluster and characterization in vascular endothelial cells and platelets. J. Biol. Chem. 273, 15061-15068 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 15061-15068
-
-
Schmidt, V.A.1
-
18
-
-
0032514474
-
A dual thrombin receptor system for platelet activation
-
Kahn, M. L. et al. A dual thrombin receptor system for platelet activation. Nature 394, 690-694 (1998).
-
(1998)
Nature
, vol.394
, pp. 690-694
-
-
Kahn, M.L.1
-
19
-
-
0034611727
-
PAR3 is a co-factor for PAR4 activation by thrombin
-
Nakanishi-Matsui, M. et al. PAR3 is a co-factor for PAR4 activation by thrombin. Nature 404, 609-613 (2000).
-
(2000)
Nature
, vol.404
, pp. 609-613
-
-
Nakanishi-Matsui, M.1
-
20
-
-
0033559805
-
Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin
-
Kahn, M. L., Nakanishi-Matsui, M., Shapiro, M. J., Ishihara, H. & Coughlin, S. R. Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin. J. Clin. Invest. 103, 879-887 (1999).
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 879-887
-
-
Kahn, M.L.1
Nakanishi-Matsui, M.2
Shapiro, M.J.3
Ishihara, H.4
Coughlin, S.R.5
-
21
-
-
0037036069
-
Activation of endothelial cell protease activated receptor 1 by the protein C pathway
-
Riewald, M., Petrovan, R. J., Donner, A., Mueller, B. M. & Ruf, W. Activation of endothelial cell protease activated receptor 1 by the protein C pathway. Science 296, 1880-1882 (2002).
-
(2002)
Science
, vol.296
, pp. 1880-1882
-
-
Riewald, M.1
Petrovan, R.J.2
Donner, A.3
Mueller, B.M.4
Ruf, W.5
-
22
-
-
0034324177
-
Factor Xa activates endothelial cells by a receptor cascade between EPR-1 and PAR-2
-
Bono, F. et al. Factor Xa activates endothelial cells by a receptor cascade between EPR-1 and PAR-2. Arterioscler. Thromb. Vasc. Biol. 20, E107-E112 (2000).
-
(2000)
Arterioscler. Thromb. Vasc. Biol.
, vol.20
-
-
Bono, F.1
-
23
-
-
0034714379
-
Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates
-
Takeuchi, T. et al. Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates. J. Biol. Chem. 275, 26333-26342 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26333-26342
-
-
Takeuchi, T.1
-
24
-
-
0035019636
-
Proteinase-activated receptors
-
Macfarlane, S. R., Seatter, M. J., Kanke, T., Hunter, G. D. & Plevin, R. Proteinase-activated receptors. Pharmacol. Rev. 53, 245-282 (2001).
-
(2001)
Pharmacol. Rev.
, vol.53
, pp. 245-282
-
-
Macfarlane, S.R.1
Seatter, M.J.2
Kanke, T.3
Hunter, G.D.4
Plevin, R.5
-
25
-
-
0034648757
-
Thrombin signalling and protease-activated receptors
-
Coughlin, S. R. Thrombin signalling and protease-activated receptors. Nature 407, 258-264 (2000).
-
(2000)
Nature
, vol.407
, pp. 258-264
-
-
Coughlin, S.R.1
-
26
-
-
0032100686
-
i-inducing protease-activated receptors (PAR-1 and PAR-2) in rat astrocytes and C6 glioma cells
-
i-inducing protease-activated receptors (PAR-1 and PAR-2) in rat astrocytes and C6 glioma cells. Neuroscience 86, 597-609 (1998).
-
(1998)
Neuroscience
, vol.86
, pp. 597-609
-
-
Ubl, J.J.1
Vohringer, C.2
Reiser, G.3
-
27
-
-
0030774851
-
Protease-activated receptor-2 (PAR-2) is present in the rat hippocampus and is associated with neurodegeneration
-
Smith-Swintosky, V. L. et al. Protease-activated receptor-2 (PAR-2) is present in the rat hippocampus and is associated with neurodegeneration. J. Neurochem. 69, 1890-1896 (1997).
-
(1997)
J. Neurochem.
, vol.69
, pp. 1890-1896
-
-
Smith-Swintosky, V.L.1
-
28
-
-
0036285822
-
Four different types of protease-activated receptors are widely expressed in the brain and are up-regulated in hippocampus by severe ischemia
-
Striggow, F. et al. Four different types of protease-activated receptors are widely expressed in the brain and are up-regulated in hippocampus by severe ischemia. Eur. J. Neurosci. 14, 595-608 (2001). Determination of the neuronal localization of the four PAR subtypes and their altered expression during ischaemia.
-
(2001)
Eur. J. Neurosci.
, vol.14
, pp. 595-608
-
-
Striggow, F.1
-
29
-
-
0036006726
-
Four subtypes of protease-activated receptors, co-expressed in rat astrocytes, evoke different physiological signaling
-
Wang, H., Ubl, J. J. & Reiser, G. Four subtypes of protease-activated receptors, co-expressed in rat astrocytes, evoke different physiological signaling. Glia 37, 53-63 (2002). Demonstration of the expression of all four PARs on rodent astrocytes, as well as of some downstream proliferative effects of PAR activation on astrocytes.
-
(2002)
Glia
, vol.37
, pp. 53-63
-
-
Wang, H.1
Ubl, J.J.2
Reiser, G.3
-
30
-
-
0032578046
-
Thrombin induced inhibition of neurite outgrowth from dorsal root ganglion neurons
-
Gill, J. S., Pitts, K., Rusnak, F. M., Owen, W. G. & Windebank, A. J. Thrombin induced inhibition of neurite outgrowth from dorsal root ganglion neurons. Brain Res. 797, 321-327 (1998).
-
(1998)
Brain Res.
, vol.797
, pp. 321-327
-
-
Gill, J.S.1
Pitts, K.2
Rusnak, F.M.3
Owen, W.G.4
Windebank, A.J.5
-
31
-
-
0033971235
-
Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism
-
Steinhoff, M. et al. Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism Nature Med. 6, 151-158 (2000). This study showed the production of proinflammatory neuropeptides, calcitonin gene-related peptide and substance P on PAR2-expressing primary spinal afferent neurons, and their release on PAR2 activation.
-
(2000)
Nature Med.
, vol.6
, pp. 151-158
-
-
Steinhoff, M.1
-
32
-
-
0345004978
-
Thrombin and mast cell tryptase regulate guinea-pig myenteric neurons through proteinase-activated receptors-1 and -2
-
Corvera, C. U. et al. Thrombin and mast cell tryptase regulate guinea-pig myenteric neurons through proteinase-activated receptors-1 and -2. J. Physiol. (Lond.) 517, 741-756 (1999).
-
(1999)
J. Physiol. (Lond.)
, vol.517
, pp. 741-756
-
-
Corvera, C.U.1
-
33
-
-
0037335786
-
Mast cell tryptase and proteinase-activated receptor 2 induce hyperexcitability of guinea-pig submucosal neurons
-
Reed, D. E. et al. Mast cell tryptase and proteinase-activated receptor 2 induce hyperexcitability of guinea-pig submucosal neurons. J. Physiol. (Lond.) 547, 531-542 (2003). Demonstration that the activation of Par2 on submucosal neurons by mast-cell tryptase led to neuronal depolarization and hyperexcitability.
-
(2003)
J. Physiol. (Lond.)
, vol.547
, pp. 531-542
-
-
Reed, D.E.1
-
34
-
-
0025857712
-
Prothrombin mRNA is expressed by cells of the nervous system
-
Dihanich, M., Kaser, M., Reinhard, E. Cunningham, D. & Monard, D. Prothrombin mRNA is expressed by cells of the nervous system. Neuron 6, 575-581 (1991).
-
(1991)
Neuron
, vol.6
, pp. 575-581
-
-
Dihanich, M.1
Kaser, M.2
Reinhard, E.3
Cunningham, D.4
Monard, D.5
-
35
-
-
0026002929
-
Production of thrombin and antithrombin III by brain and astroglial cell cultures
-
Deschepper, C. F., Bigornia, V., Berens, M. E. & Lapointe, M. C. Production of thrombin and antithrombin III by brain and astroglial cell cultures. Brain Res. Mol. Brain Res. 11, 355-358 (1991).
-
(1991)
Brain Res. Mol. Brain Res.
, vol.11
, pp. 355-358
-
-
Deschepper, C.F.1
Bigornia, V.2
Berens, M.E.3
Lapointe, M.C.4
-
36
-
-
0028914068
-
Cellular localization of thrombin receptor mRNA in rat brain: Expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA
-
Weinstein, J. R., Gold, S. J., Cunningham, D. D. & Gall, C. M. Cellular localization of thrombin receptor mRNA in rat brain: expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA. J. Neurosci. 15, 2906-2919 (1995).
-
(1995)
J. Neurosci.
, vol.15
, pp. 2906-2919
-
-
Weinstein, J.R.1
Gold, S.J.2
Cunningham, D.D.3
Gall, C.M.4
-
37
-
-
0033435136
-
Expression of factor X in both the rat brain and cells of the central nervous system
-
Shikamoto, Y. & Morita, T. Expression of factor X in both the rat brain and cells of the central nervous system. FEBS Lett. 463, 387-389 (1999).
-
(1999)
FEBS Lett.
, vol.463
, pp. 387-389
-
-
Shikamoto, Y.1
Morita, T.2
-
38
-
-
0023332815
-
Intestinal mucosal mast cells in normal and nematode-infected rat intestines are in intimate contact with peptidergic nerves
-
Stead, R. H. et al. Intestinal mucosal mast cells in normal and nematode-infected rat intestines are in intimate contact with peptidergic nerves. Proc. Natl Acad. Sci. USA 84, 2975-2979 (1987).
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 2975-2979
-
-
Stead, R.H.1
-
39
-
-
0025055444
-
Mast cells: The immune gate to the brain
-
Thecharides, T. C. Mast cells: the immune gate to the brain. Life Sci 46, 607-617 (1990).
-
(1990)
Life Sci
, vol.46
, pp. 607-617
-
-
Thecharides, T.C.1
-
40
-
-
0034022706
-
Purification and characterization of a trypsin-like serine proteinase from rat brain slices that degrades laminin and type IV collagen and stimulates protease-activated receptor-2
-
Sawada, K., Nishibori, M., Nakaya, N., Wang, Z. & Saeki, K. Purification and characterization of a trypsin-like serine proteinase from rat brain slices that degrades laminin and type IV collagen and stimulates protease-activated receptor-2. J. Neurochem. 74, 1731-1738 (2000).
-
(2000)
J. Neurochem.
, vol.74
, pp. 1731-1738
-
-
Sawada, K.1
Nishibori, M.2
Nakaya, N.3
Wang, Z.4
Saeki, K.5
-
41
-
-
0027743598
-
Cloning of the cDNA encoding human brain trypsinogen and characterization of its product
-
Wiegand, U., Corbach, S., Minn, A., Kang, J. & Muller-Hill, B. Cloning of the cDNA encoding human brain trypsinogen and characterization of its product. Gene 136, 167-175 (1993).
-
(1993)
Gene
, vol.136
, pp. 167-175
-
-
Wiegand, U.1
Corbach, S.2
Minn, A.3
Kang, J.4
Muller-Hill, B.5
-
42
-
-
0025255579
-
Reciprocal modulation of astrocyte stellation by thrombin and protease nexin-1
-
Cavanaugh, K. P., Gurwitz, D., Cunningham, D. D. & Bradshaw, R. A. Reciprocal modulation of astrocyte stellation by thrombin and protease nexin-1. J. Neurochem. 54, 1736-1743 (1990).
-
(1990)
J. Neurochem.
, vol.54
, pp. 1736-1743
-
-
Cavanaugh, K.P.1
Gurwitz, D.2
Cunningham, D.D.3
Bradshaw, R.A.4
-
43
-
-
0028085095
-
Thrombin receptor peptides induce shape change in neonatal murine astrocytes in culture
-
Beecher, K. L., Andersen, T. T., Fenton, J. W. & Festoff, B. W. Thrombin receptor peptides induce shape change in neonatal murine astrocytes in culture. J. Neurosci. Res 37, 108-115 (1994).
-
(1994)
J. Neurosci. Res
, vol.37
, pp. 108-115
-
-
Beecher, K.L.1
Andersen, T.T.2
Fenton, J.W.3
Festoff, B.W.4
-
44
-
-
0028873060
-
Thrombin receptor activation stimulates astrocyte proliferation and reversal of stellation by distinct pathways: Involvement of tyrosine phosphorylation
-
Grabham, P. & Cunningham, D. D. Thrombin receptor activation stimulates astrocyte proliferation and reversal of stellation by distinct pathways: involvement of tyrosine phosphorylation. J. Neurochem. 64, 583-591 (1995).
-
(1995)
J. Neurochem.
, vol.64
, pp. 583-591
-
-
Grabham, P.1
Cunningham, D.D.2
-
46
-
-
0036838021
-
Thrombin (PAR-1)-induced proliferation in astrocytes via MAPK involves multiple signaling pathways
-
Wang, H., Ubl, J. J., Stricker, R. & Reiser, G. Thrombin (PAR-1)-induced proliferation in astrocytes via MAPK involves multiple signaling pathways Am. J. Physiol. Cell. Physiol. 283, C1351-C1364 (2002). Demonstration of the involvement of the extracellular signal-regulated kinase and PLC pathways in thrombin-induced astrocytic proliferation.
-
(2002)
Am. J. Physiol. Cell. Physiol.
, vol.283
-
-
Wang, H.1
Ubl, J.J.2
Stricker, R.3
Reiser, G.4
-
47
-
-
0037332454
-
2+-sensitive tyrosine kinase Pyk2 and Src in thrombin signalling in rat astrocytes
-
2+-sensitive tyrosine kinase Pyk2 and Src in thrombin signalling in rat astrocytes. J. Neurochem. 84, 1349-1357 (2003).
-
(2003)
J. Neurochem.
, vol.84
, pp. 1349-1357
-
-
Wang, H.1
Reiser, G.2
-
48
-
-
0027470910
-
Thrombin is a regulator of astrocytic endothelin-1
-
Ehrenreich, H. et al. Thrombin is a regulator of astrocytic endothelin-1 Brain Res. 600, 201-207 (1993).
-
(1993)
Brain Res.
, vol.600
, pp. 201-207
-
-
Ehrenreich, H.1
-
49
-
-
0027510492
-
Enhancement of the synthesis and secretion of nerve growth factor in primary cultures of glial cells by proteases: A possible involvement of thrombin
-
Neveu, I., Jehan, F., Jandrot-Perrus, M., Wion, D. & Brachet, P. Enhancement of the synthesis and secretion of nerve growth factor in primary cultures of glial cells by proteases: a possible involvement of thrombin. J. Neurochem. 60, 858-867 (1993).
-
(1993)
J. Neurochem.
, vol.60
, pp. 858-867
-
-
Neveu, I.1
Jehan, F.2
Jandrot-Perrus, M.3
Wion, D.4
Brachet, P.5
-
50
-
-
0029896145
-
Transduction mechanisms involved in thrombin receptor-induced nerve growth factor secretion and cell division in primary cultures of astrocytes
-
Debeir, T., Gueugnon, J., Vige, X. & Benavides, J. Transduction mechanisms involved in thrombin receptor-induced nerve growth factor secretion and cell division in primary cultures of astrocytes. J. Neurochem. 66, 2320-2328 (1996).
-
(1996)
J. Neurochem.
, vol.66
, pp. 2320-2328
-
-
Debeir, T.1
Gueugnon, J.2
Vige, X.3
Benavides, J.4
-
51
-
-
0029790022
-
Exposure of astrocytes to thrombin reduces levels of the metabotropic glutamate receptor mGluR5
-
Miller, S., Sehati, N., Romano, C. & Cotman, C. W. Exposure of astrocytes to thrombin reduces levels of the metabotropic glutamate receptor mGluR5. J. Neurochem. 67, 1435-1447 (1996).
-
(1996)
J. Neurochem.
, vol.67
, pp. 1435-1447
-
-
Miller, S.1
Sehati, N.2
Romano, C.3
Cotman, C.W.4
-
52
-
-
0027196148
-
Glutamate induces the growth factors NGF, bFGE the receptor FGF-R1 and c-fos mRNA expression in rat astrocyte culture
-
Pechan, P. A., Chowdhury, K., Gerdes, W. & Seifert, W. Glutamate induces the growth factors NGF, bFGE the receptor FGF-R1 and c-fos mRNA expression in rat astrocyte culture. Neurosci. Lett. 153, 111-114 (1993).
-
(1993)
Neurosci. Lett.
, vol.153
, pp. 111-114
-
-
Pechan, P.A.1
Chowdhury, K.2
Gerdes, W.3
Seifert, W.4
-
53
-
-
0030886438
-
The metabotropic glutamate receptor mGluR5 induces calcium oscillations in cultured astrocytes via protein kinase C phosphorylation
-
Nakahara, K., Okada, M. & Nakanishi, S. The metabotropic glutamate receptor mGluR5 induces calcium oscillations in cultured astrocytes via protein kinase C phosphorylation. J. Neurochem. 69, 1467-1475 (1997).
-
(1997)
J. Neurochem.
, vol.69
, pp. 1467-1475
-
-
Nakahara, K.1
Okada, M.2
Nakanishi, S.3
-
54
-
-
0033083661
-
Metabotropic glutamate receptor agonists reduce glutamate release from cultured astrocytes
-
Ye, Z. C. & Sontheimer, H. Metabotropic glutamate receptor agonists reduce glutamate release from cultured astrocytes Glia 25, 270-281 (1999).
-
(1999)
Glia
, vol.25
, pp. 270-281
-
-
Ye, Z.C.1
Sontheimer, H.2
-
55
-
-
0011811083
-
Thrombin modulates and reverses neuroblastoma neurite outgrowth
-
Gurwitz, D. & Cunningham, D. D. Thrombin modulates and reverses neuroblastoma neurite outgrowth. Proc. Natl Acad. Sci. USA 85, 3440-3444 (1988).
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 3440-3444
-
-
Gurwitz, D.1
Cunningham, D.D.2
-
56
-
-
0022897760
-
A glia-derived neurite promoting factor with protease inhibitory activity belongs to the protease nexins
-
Gloor, S., Odink, K., Guenther, J., Nick, H. & Monard, D. A glia-derived neurite promoting factor with protease inhibitory activity belongs to the protease nexins. Cell 47, 687-893 (1986).
-
(1986)
Cell
, vol.47
, pp. 687-893
-
-
Gloor, S.1
Odink, K.2
Guenther, J.3
Nick, H.4
Monard, D.5
-
57
-
-
0343742615
-
Involvement of protease-activated receptor-1 in the in vitro development of mesencephalic dopaminergic neurons
-
Debeir, T., Benavides, J. & Vige, X. Involvement of protease-activated receptor-1 in the in vitro development of mesencephalic dopaminergic neurons. Neuroscience 82, 739-752 (1998).
-
(1998)
Neuroscience
, vol.82
, pp. 739-752
-
-
Debeir, T.1
Benavides, J.2
Vige, X.3
-
58
-
-
17344365478
-
Thrombin perturbs neurite outgrowth and induces apoptotic cell death in enriched chick spinal motoneuron cultures through caspase activation
-
Turgeon, V. L., Lloyd, E. D., Wang, S., Festoff, B. W. & Houenou, L. J. Thrombin perturbs neurite outgrowth and induces apoptotic cell death in enriched chick spinal motoneuron cultures through caspase activation. J. Neurosci. 18, 6882-6891 (1998).
-
(1998)
J. Neurosci.
, vol.18
, pp. 6882-6891
-
-
Turgeon, V.L.1
Lloyd, E.D.2
Wang, S.3
Festoff, B.W.4
Houenou, L.J.5
-
59
-
-
0023698784
-
Cell-derived proteases and protease inhibitors as regulators of neurite outgrowth
-
Monard, D. Cell-derived proteases and protease inhibitors as regulators of neurite outgrowth. Trends Neurosci. 11, 541-544 (1988).
-
(1988)
Trends Neurosci.
, vol.11
, pp. 541-544
-
-
Monard, D.1
-
60
-
-
0027948168
-
Proteolytic action of thrombin is required for electrical activity-dependent synapse reduction
-
Liu, Y., Fields, R. D., Festoff, B. W. & Nelson, P. G. Proteolytic action of thrombin is required for electrical activity-dependent synapse reduction. Proc. Natl Acad. Sci. USA 91, 10300-10304 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 10300-10304
-
-
Liu, Y.1
Fields, R.D.2
Festoff, B.W.3
Nelson, P.G.4
-
61
-
-
0028296632
-
Proteolytic activity, synapse elimination, and the Hebb synapse
-
Liu, Y., Fields, R. D., Fitzgerald, S., Festoff, B. W. & Nelson, P. G. Proteolytic activity, synapse elimination, and the Hebb synapse. J. Neurobiol. 25, 325-335 (1994).
-
(1994)
J. Neurobiol.
, vol.25
, pp. 325-335
-
-
Liu, Y.1
Fields, R.D.2
Fitzgerald, S.3
Festoff, B.W.4
Nelson, P.G.5
-
62
-
-
0034660448
-
Potentiation of NMDA receptor function by the serine protease thrombin
-
Gingdch, M. B., Junge, C. E., Lyuboslavsky, P. & Traynelis, S. F. Potentiation of NMDA receptor function by the serine protease thrombin. J. Neurosci. 20, 4582-4595 (2000).
-
(2000)
J. Neurosci.
, vol.20
, pp. 4582-4595
-
-
Gingdch, M.B.1
Junge, C.E.2
Lyuboslavsky, P.3
Traynelis, S.F.4
-
63
-
-
0034888212
-
Agonists of proteinase-activated receptor 1 induce plasma extravasation by a neurogenic mechanism
-
de Garavilla, L. et al. Agonists of proteinase-activated receptor 1 induce plasma extravasation by a neurogenic mechanism. Br. J. Pharmacol. 133, 975-987 (2001).
-
(2001)
Br. J. Pharmacol.
, vol.133
, pp. 975-987
-
-
De Garavilla, L.1
-
64
-
-
0035941170
-
Agonists of proteinase-activated receptor 2 excite guinea pig ileal myenteric neurons
-
Linden, D. R., Manning, B. P., Bunnett, N. W. & Mawe, G. M. Agonists of proteinase-activated receptor 2 excite guinea pig ileal myenteric neurons. Eur. J. Pharmacol. 431, 311-314 (2001).
-
(2001)
Eur. J. Pharmacol.
, vol.431
, pp. 311-314
-
-
Linden, D.R.1
Manning, B.P.2
Bunnett, N.W.3
Mawe, G.M.4
-
65
-
-
0142243114
-
Stimulation of the proteinase-activated receptor 2 excites jejunal afferent nerves in anaesthetised rats
-
Kirkup, A. J., Jiang, W., Bunnett, N. W. & Grundy, D. Stimulation of the proteinase-activated receptor 2 excites jejunal afferent nerves in anaesthetised rats. J. Physiol. 552, 589-601 (2003).
-
(2003)
J. Physiol.
, vol.552
, pp. 589-601
-
-
Kirkup, A.J.1
Jiang, W.2
Bunnett, N.W.3
Grundy, D.4
-
66
-
-
0036828264
-
Serine proteases excite myenteric neurons through protease-activated receptors in guinea pig small intestine
-
Gao, C. et al. Serine proteases excite myenteric neurons through protease-activated receptors in guinea pig small intestine. Gastroenterology 123, 1554-1564 (2002).
-
(2002)
Gastroenterology
, vol.123
, pp. 1554-1564
-
-
Gao, C.1
-
67
-
-
0036193921
-
Proteinase-activated receptor-1 agonists attenuate nociception in response to noxious stimuli
-
Asfaha, S., Brussee, V., Chapman, K., Zochodne, D. W. & Vergnolle, N. Proteinase-activated receptor-1 agonists attenuate nociception in response to noxious stimuli. Br. J. Pharmacol. 135, 1101-1106 (2002).
-
(2002)
Br. J. Pharmacol.
, vol.135
, pp. 1101-1106
-
-
Asfaha, S.1
Brussee, V.2
Chapman, K.3
Zochodne, D.W.4
Vergnolle, N.5
-
68
-
-
0034927070
-
Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway
-
Vergnolle, N. et al. Proteinase-activated receptor-2 and hyperalgesia: a novel pain pathway. Nature Med. 7, 821-826 (2001). Demonstration of neurokinin-1-receptor-dependent and PAR2-induced thermal and mechanical hyperalgesia.
-
(2001)
Nature Med.
, vol.7
, pp. 821-826
-
-
Vergnolle, N.1
-
69
-
-
0035890075
-
The proteinase-activated receptor 2 is involved in nociception
-
Hoogerwerf, W. A. et al. The proteinase-activated receptor 2 is involved in nociception. J. Neurosci. 21, 9036-9042 (2001).
-
(2001)
J. Neurosci.
, vol.21
, pp. 9036-9042
-
-
Hoogerwerf, W.A.1
-
70
-
-
0038720558
-
Proteinase-activated receptor-2 mediates itch: A novel pathway for pruritus in human skin
-
Steinhoff, M. et al. Proteinase-activated receptor-2 mediates itch: a novel pathway for pruritus in human skin. J. Neurosci. 23, 6176-6180 (2003).
-
(2003)
J. Neurosci.
, vol.23
, pp. 6176-6180
-
-
Steinhoff, M.1
-
71
-
-
0032968080
-
Injury-induced gelatinase and thrombin-like activities in regenerating and nonregenerating nervous systems
-
Friedmann, I., Faber-Elman, A., Yoles, E. & Schwartz, M. Injury-induced gelatinase and thrombin-like activities in regenerating and nonregenerating nervous systems. FASEB J. 13, 533-543 (1999).
-
(1999)
FASEB J.
, vol.13
, pp. 533-543
-
-
Friedmann, I.1
Faber-Elman, A.2
Yoles, E.3
Schwartz, M.4
-
72
-
-
0031844717
-
Changes in the expression of protease-activated receptor 1 and protease nexin-1 mRNA during rat nervous system development and after nerve lesion
-
Niclou, S. P., Suidan, H. S., Pavlik, A., Vejsada, R. & Monard, D. Changes in the expression of protease-activated receptor 1 and protease nexin-1 mRNA during rat nervous system development and after nerve lesion. Eur. J. Neurosci. 10, 1590-1607 (1998).
-
(1998)
Eur. J. Neurosci.
, vol.10
, pp. 1590-1607
-
-
Niclou, S.P.1
Suidan, H.S.2
Pavlik, A.3
Vejsada, R.4
Monard, D.5
-
73
-
-
0033798625
-
Intestinal type 2 proteinase-activated receptors: Expression in opioid-sensitive secretomotor neural circuits that mediate epithelial ion transport
-
Green, B. T., Bunnett, N. W., Kulkarni-Narla, A., Steinhoff, M. & Brown, D. R. Intestinal type 2 proteinase-activated receptors: expression in opioid-sensitive secretomotor neural circuits that mediate epithelial ion transport. J. Pharmacol. Exp. Ther. 295, 410-416 (2000).
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.295
, pp. 410-416
-
-
Green, B.T.1
Bunnett, N.W.2
Kulkarni-Narla, A.3
Steinhoff, M.4
Brown, D.R.5
-
74
-
-
0034983372
-
The protease-activated receptor-2 agonist induces gastric mucus secretion and mucosal cytoprotection
-
Kawabata, A. et al. The protease-activated receptor-2 agonist induces gastric mucus secretion and mucosal cytoprotection. J. Clin. Invest 107, 1443-1450 (2001).
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 1443-1450
-
-
Kawabata, A.1
-
75
-
-
0037040862
-
Protease-activated receptor-2 activation causes EDHF-like coronary vasodilaton: Selective preservation in ischemia/reperfusion injury: Involvement of lipoxygenase products, VR1 receptors, and C-fibers
-
McLean, P. G., Aston, D., Sarkar, D. & Ahluwalia, A. Protease-activated receptor-2 activation causes EDHF-like coronary vasodilaton: selective preservation in ischemia/reperfusion injury: involvement of lipoxygenase products, VR1 receptors, and C-fibers. Circ. Res. 90, 465-472 (2002).
-
(2002)
Circ. Res.
, vol.90
, pp. 465-472
-
-
McLean, P.G.1
Aston, D.2
Sarkar, D.3
Ahluwalia, A.4
-
77
-
-
0030007646
-
Thrombin, its receptor and protease nexin I, its potent serpin, in the nervous system
-
Festoff, B. W., Smirnova, I. V., Ma, J. & Citron, B. A. Thrombin, its receptor and protease nexin I, its potent serpin, in the nervous system. Semin. Thromb. Hemost. 22, 267-271 (1996).
-
(1996)
Semin. Thromb. Hemost.
, vol.22
, pp. 267-271
-
-
Festoff, B.W.1
Smirnova, I.V.2
Ma, J.3
Citron, B.A.4
-
78
-
-
16944366731
-
Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities
-
Donovan, F. M., Pike, C. J., Cotman, C. W. & Cunningham, D. D. Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities. J. Neurosci. 17, 5316-5326 (1997).
-
(1997)
J. Neurosci.
, vol.17
, pp. 5316-5326
-
-
Donovan, F.M.1
Pike, C.J.2
Cotman, C.W.3
Cunningham, D.D.4
-
79
-
-
0029012029
-
Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults
-
Vaughan, P. J., Pike, C. J., Cotman, C. W. & Cunningham, D. D. Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults. J. Neurosci. 15, 5389-5401 (1995). This report showed that PAR1 activation could protect neurons and astrocytes from the deleterious effects of glucose/growth supplement deprivation or oxidative stress.
-
(1995)
J. Neurosci.
, vol.15
, pp. 5389-5401
-
-
Vaughan, P.J.1
Pike, C.J.2
Cotman, C.W.3
Cunningham, D.D.4
-
80
-
-
0030759613
-
Apoptosis in neurodegenerative disorders
-
Stefanis, L., Burke, R. E. & Greene, L. A. Apoptosis in neurodegenerative disorders. Curr. Opin. Neurol. 10, 299-305 (1997).
-
(1997)
Curr. Opin. Neurol.
, vol.10
, pp. 299-305
-
-
Stefanis, L.1
Burke, R.E.2
Greene, L.A.3
-
81
-
-
0034186091
-
Motor neuron cell death in wobbler mutant mice follows overexpression of the G-protein-coupled, protease-activated receptor for thrombin
-
Festoff, B. W. et al. Motor neuron cell death in wobbler mutant mice follows overexpression of the G-protein-coupled, protease-activated receptor for thrombin. Mol. Med. 6, 410-429 (2000).
-
(2000)
Mol. Med.
, vol.6
, pp. 410-429
-
-
Festoff, B.W.1
-
82
-
-
0344923324
-
Up-regulation of proteinase-activated receptor 1 expression in astrocytes during HIV encephalitis
-
Boven, L. A. et al. Up-regulation of proteinase-activated receptor 1 expression in astrocytes during HIV encephalitis. J. Immunol. 170, 2638-2646 (2003). Demonstration of the proinflammatory role of astrocytic PAR1 activation in HIV encephalitis.
-
(2003)
J. Immunol.
, vol.170
, pp. 2638-2646
-
-
Boven, L.A.1
-
83
-
-
0033822556
-
Thrombin-induced activation of cultured rodent microglia
-
Moller, T., Hanisch, U. K. & Ransom, B. R. Thrombin-induced activation of cultured rodent microglia J. Neurochem. 75, 1539-1547 (2000).
-
(2000)
J. Neurochem.
, vol.75
, pp. 1539-1547
-
-
Moller, T.1
Hanisch, U.K.2
Ransom, B.R.3
-
84
-
-
0036326804
-
Participation of protease-activated receptor-1 in thrombin-induced microglial activation
-
Suo, Z. et al. Participation of protease-activated receptor-1 in thrombin-induced microglial activation. J. Neurochem. 80, 655-666 (2002).
-
(2002)
J. Neurochem.
, vol.80
, pp. 655-666
-
-
Suo, Z.1
-
85
-
-
0032557654
-
Signaling pathways involved in thrombin-induced cell protection
-
Donovan, F. M. & Cunningham, D. D. Signaling pathways involved in thrombin-induced cell protection. J. Biol. Chem. 273, 12746-12752 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 12746-12752
-
-
Donovan, F.M.1
Cunningham, D.D.2
-
86
-
-
0034053127
-
The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations
-
Striggow, F. et al. The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations. Proc. Natl. Acad. Sci. USA 97, 2264-2269 (2000). Report of the neuroprotective/degenerative roles of the thrombin/PAR1 axis in ischaemia.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 2264-2269
-
-
Striggow, F.1
-
87
-
-
0033000918
-
Attenuation of thrombin-induced brain edema by cerebral thrombin preconditioning
-
Xi, G., Keep, R. F., Hua, Y., Xiang, J. & Hoff, J. T. Attenuation of thrombin-induced brain edema by cerebral thrombin preconditioning. Stroke 30, 1247-1255 (1999).
-
(1999)
Stroke
, vol.30
, pp. 1247-1255
-
-
Xi, G.1
Keep, R.F.2
Hua, Y.3
Xiang, J.4
Hoff, J.T.5
-
88
-
-
0035937433
-
Activation of p44/42 mitogen activated protein kinases in thrombin-induced brain tolerance
-
Xi, G., Hua, Y., Keep, R. F., Duong, H. K. & Hoff, J. T. Activation of p44/42 mitogen activated protein kinases in thrombin-induced brain tolerance. Brain Res 895, 153-159 (2001).
-
(2001)
Brain Res
, vol.895
, pp. 153-159
-
-
Xi, G.1
Hua, Y.2
Keep, R.F.3
Duong, H.K.4
Hoff, J.T.5
-
89
-
-
0027326873
-
Thrombin may contribute to the pathophysiology of central nervous system injury
-
Nishino, A. et al. Thrombin may contribute to the pathophysiology of central nervous system injury. J. Neurotrauma 10, 167-179 (1993).
-
(1993)
J. Neurotrauma
, vol.10
, pp. 167-179
-
-
Nishino, A.1
-
90
-
-
0030829885
-
The role of thrombin-like (serine) proteases in the development, plasticity and pathology of the nervous system
-
Turgeon, V. L. & Houenou, L. J. The role of thrombin-like (serine) proteases in the development, plasticity and pathology of the nervous system. Brain Res. Brain Res. Rev. 25, 85-95 (1997).
-
(1997)
Brain Res. Brain Res. Rev.
, vol.25
, pp. 85-95
-
-
Turgeon, V.L.1
Houenou, L.J.2
-
91
-
-
0028566867
-
Protease nexin-1, a potent thrombin inhibitor, is reduced around cerebral blood vessels in Alzheimer's disease
-
Vaughan, P. J., Su, J., Cotman, C. W. & Cunningham, D. D. Protease nexin-1, a potent thrombin inhibitor, is reduced around cerebral blood vessels in Alzheimer's disease. Brain Res. 668, 160-170 (1994).
-
(1994)
Brain Res.
, vol.668
, pp. 160-170
-
-
Vaughan, P.J.1
Su, J.2
Cotman, C.W.3
Cunningham, D.D.4
-
92
-
-
0029914487
-
Thrombin attenuates neuronal cell death and modulates astrocyte reactivity induced by β-amyloid in vitro
-
Pike, C. J., Vaughan, P. J., Cunningham, D. D. & Cotman, C. W. Thrombin attenuates neuronal cell death and modulates astrocyte reactivity induced by β-amyloid in vitro. J. Neurochem 66, 1374-1382 (1996).
-
(1996)
J. Neurochem.
, vol.66
, pp. 1374-1382
-
-
Pike, C.J.1
Vaughan, P.J.2
Cunningham, D.D.3
Cotman, C.W.4
-
93
-
-
0035235444
-
Neuroimmune and neurovirological aspects of human immunodeficiency virus infection
-
Power, C. & Johnson, R. T. Neuroimmune and neurovirological aspects of human immunodeficiency virus infection. Adv. Virus Res. 56, 389-433 (2001).
-
(2001)
Adv. Virus Res.
, vol.56
, pp. 389-433
-
-
Power, C.1
Johnson, R.T.2
-
94
-
-
0036194251
-
Progress in clinical neurosciences: The neuropathogenesis of HIV infection: Host-virus interaction and the impact of therapy
-
Power, C., Gill, M. J. & Johnson, R. T. Progress in clinical neurosciences: the neuropathogenesis of HIV infection: host-virus interaction and the impact of therapy. Can. J. Neurol. Sci. 29, 19-32 (2002).
-
(2002)
Can. J. Neurol. Sci.
, vol.29
, pp. 19-32
-
-
Power, C.1
Gill, M.J.2
Johnson, R.T.3
-
95
-
-
0025969914
-
The V3 loops of the HIV-1 and HIV-2 surface glycoproteins contain proteolytic cleavage sites: A possible function in viral fusion?
-
Clements, G. J. et al. The V3 loops of the HIV-1 and HIV-2 surface glycoproteins contain proteolytic cleavage sites: a possible function in viral fusion? AIDS Res. Hum. Retroviruses 7, 3-16 (1991).
-
(1991)
AIDS Res. Hum. Retroviruses
, vol.7
, pp. 3-16
-
-
Clements, G.J.1
-
96
-
-
0027481774
-
Effect of mutations in the V3 loop of HIV-1 gp120 on infectivity and susceptibility to proteolytic cleavage
-
Schulz, T. F. et al. Effect of mutations in the V3 loop of HIV-1 gp120 on infectivity and susceptibility to proteolytic cleavage. AIDS Res. Hum. Retroviruses 9, 159-166 (1993).
-
(1993)
AIDS Res. Hum. Retroviruses
, vol.9
, pp. 159-166
-
-
Schulz, T.F.1
-
97
-
-
0028103736
-
Conformational rearrangements required of the V3 loop of HIV-1 gp120 for proteolytic cleavage and infection
-
Johnson, M. E., Lin, Z., Padmanabhan, K., Tulinsky, A. & Kahn, M. Conformational rearrangements required of the V3 loop of HIV-1 gp120 for proteolytic cleavage and infection. FEBS Lett. 337, 4-8 (1994).
-
(1994)
FEBS Lett.
, vol.337
, pp. 4-8
-
-
Johnson, M.E.1
Lin, Z.2
Padmanabhan, K.3
Tulinsky, A.4
Kahn, M.5
-
99
-
-
0030445074
-
Cellular proteases involved in the pathogenicity of enveloped animal viruses, human immunodeficiency virus, infuenza virus A and Sendai virus
-
Kido, H., Niwa, Y., Beppu, Y. & Towatari, T. Cellular proteases involved in the pathogenicity of enveloped animal viruses, human immunodeficiency virus, infuenza virus A and Sendai virus. Adv. Enzyme Regul. 36, 325-347 (1996).
-
(1996)
Adv. Enzyme Regul.
, vol.36
, pp. 325-347
-
-
Kido, H.1
Niwa, Y.2
Beppu, Y.3
Towatari, T.4
-
100
-
-
0030339827
-
Cellular proteases involved in the pathogenicity of human immunodeficiency and influenza viruses
-
Kido, H., Towatari, T., Niwa, Y., Okumura, Y. & Beppu, Y. Cellular proteases involved in the pathogenicity of human immunodeficiency and influenza viruses. Adv. Exp. Med. Biol. 389, 233-240 (1996).
-
(1996)
Adv. Exp. Med. Biol.
, vol.389
, pp. 233-240
-
-
Kido, H.1
Towatari, T.2
Niwa, Y.3
Okumura, Y.4
Beppu, Y.5
-
101
-
-
0029876273
-
T-cell membrane-associated serine protease, tryptase TL2, binds human immunodeficiency virus type 1 gp120 and cleaves the third-variable-domain loop of gp120, Neutralizing antibodies of human immunodeficiency virus type 1 inhibit cleavage of gp120
-
Niwa, Y., Yano, M., Futaki, S., Okumura, Y. & Kido, H. T-cell membrane-associated serine protease, tryptase TL2, binds human immunodeficiency virus type 1 gp120 and cleaves the third-variable-domain loop of gp120, Neutralizing antibodies of human immunodeficiency virus type 1 inhibit cleavage of gp120. Eur. J. Biochem. 237, 64-70 (1996).
-
(1996)
Eur. J. Biochem.
, vol.237
, pp. 64-70
-
-
Niwa, Y.1
Yano, M.2
Futaki, S.3
Okumura, Y.4
Kido, H.5
-
102
-
-
0027536055
-
Interaction between a membrane-associated serine proteinase of U-937 monocytes and peptides from the V3 loop of the human immunodeficiency virus type 1 (HIV-1) gp120 envelope glycoprotein
-
Avril, L. E., Di Martino-Ferrer, M., Barin, F. & Gauthier, F. Interaction between a membrane-associated serine proteinase of U-937 monocytes and peptides from the V3 loop of the human immunodeficiency virus type 1 (HIV-1) gp120 envelope glycoprotein. FEBS Lett. 317, 167-172 (1993).
-
(1993)
FEBS Lett.
, vol.317
, pp. 167-172
-
-
Avril, L.E.1
Di Martino-Ferrer, M.2
Barin, F.3
Gauthier, F.4
-
103
-
-
0028360298
-
Identification of the U-937 membrane-associated proteinase interacting with the V3 loop of HIV-1 gp120 as cathepsin G
-
Avril, L. E., Di Martino-Ferrer, M., Pignede, G., Seman, M. & Gauthier, F. Identification of the U-937 membrane-associated proteinase interacting with the V3 loop of HIV-1 gp120 as cathepsin G. FEBS Lett. 345, 81-86 (1994).
-
(1994)
FEBS Lett.
, vol.345
, pp. 81-86
-
-
Avril, L.E.1
Di Martino-Ferrer, M.2
Pignede, G.3
Seman, M.4
Gauthier, F.5
-
104
-
-
0029075688
-
Inhibition of U-937 membrane-associated cathepsin G by GP120 (IIIB) and V3 loop-derived peptides from several strains of HIV-1
-
Avdl, L. E., di Martino-Ferrer, M., Brillard-Bourdet, M. & Gauthier, F. Inhibition of U-937 membrane-associated cathepsin G by GP120 (IIIB) and V3 loop-derived peptides from several strains of HIV-1. FEBS Lett. 367, 251-256 (1995).
-
(1995)
FEBS Lett.
, vol.367
, pp. 251-256
-
-
Avdl, L.E.1
Di Martino-Ferrer, M.2
Brillard-Bourdet, M.3
Gauthier, F.4
-
105
-
-
0027092473
-
Characterization of a neutralizing monoclonal antibody to the external glycoprotein of HIV-1
-
Pal, R. et al. Characterization of a neutralizing monoclonal antibody to the external glycoprotein of HIV-1. Intervirology 34, 86-93 (1992).
-
(1992)
Intervirology
, vol.34
, pp. 86-93
-
-
Pal, R.1
-
106
-
-
0027332080
-
Role of HIV-1 envelope V3 loop cleavage in cell tropism
-
Gu, R., Westervelt, P. & Ratner, L. Role of HIV-1 envelope V3 loop cleavage in cell tropism. AIDS Res. Hum. Retroviruses. 9, 1007-1015 (1993).
-
(1993)
AIDS Res. Hum. Retroviruses
, vol.9
, pp. 1007-1015
-
-
Gu, R.1
Westervelt, P.2
Ratner, L.3
-
107
-
-
0037265689
-
The role of thrombin and thrombin receptors in ischemic, hemorrhagic and traumatic brain injury: Deleterious or protective?
-
Xi, G., Reiser, G. & Keep, R. F. The role of thrombin and thrombin receptors in ischemic, hemorrhagic and traumatic brain injury: deleterious or protective? J. Neurochem. 84, 3-9 (2003).
-
(2003)
J. Neurochem.
, vol.84
, pp. 3-9
-
-
Xi, G.1
Reiser, G.2
Keep, R.F.3
-
108
-
-
0034731502
-
Proteinase-activated receptor-1 regulation of macrophage elastase (MMP-12) secretion by serine proteinases
-
Raza, S. L., Nehring, L. C., Shapiro, S. D. & Cornelius, L. A. Proteinase-activated receptor-1 regulation of macrophage elastase (MMP-12) secretion by serine proteinases. J. Biol. Chem. 275, 41243-41250 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 41243-41250
-
-
Raza, S.L.1
Nehring, L.C.2
Shapiro, S.D.3
Cornelius, L.A.4
-
109
-
-
0038443057
-
Intracerebral hemorrhage induces macrophage activation and matrix metalloproteinases
-
Power, C. et al. Intracerebral hemorrhage induces macrophage activation and matrix metalloproteinases. Ann. Neurol. 53, 731-742 (2003).
-
(2003)
Ann. Neurol.
, vol.53
, pp. 731-742
-
-
Power, C.1
-
110
-
-
0025107628
-
Identification of IgE-positive cells and mast cells in frozen sections of multiple sclerosis brains
-
Toms, R., Weiner H. L. & Johnson, D. Identification of IgE-positive cells and mast cells in frozen sections of multiple sclerosis brains. J. Neuroimmunol. 30, 169-177 (1990).
-
(1990)
J. Neuroimmunol.
, vol.30
, pp. 169-177
-
-
Toms, R.1
Weiner, H.L.2
Johnson, D.3
-
111
-
-
0030298349
-
The mast cells of the multiple sclerosis brain
-
Ibrahim, M. Z., Reder, A. T., Lawand, R., Takash, W. & Sallouh-Khatib, S. The mast cells of the multiple sclerosis brain. J. Neuroimmunol. 70, 131-138 (1996).
-
(1996)
J. Neuroimmunol.
, vol.70
, pp. 131-138
-
-
Ibrahim, M.Z.1
Reder, A.T.2
Lawand, R.3
Takash, W.4
Sallouh-Khatib, S.5
-
112
-
-
0037452593
-
Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination
-
Pedotti, R. et al. Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination. Proc. Natl Acad. Sci. USA 100, 1867-1872 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 1867-1872
-
-
Pedotti, R.1
-
113
-
-
0036105484
-
Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis
-
Lock, C. et al. Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nature Med. 8, 500-508 (2002).
-
(2002)
Nature Med.
, vol.8
, pp. 500-508
-
-
Lock, C.1
-
114
-
-
0028908819
-
Elevated mast cell tryptase in cerebrospinal fluid of multiple sclerosis patients
-
Rozniecki, J. J., Hauser, S. L., Stein, M., Lincoln, R. & Theoharides, T. C. Elevated mast cell tryptase in cerebrospinal fluid of multiple sclerosis patients. Ann. Neurol. 37, 63-66 (1995).
-
(1995)
Ann. Neurol.
, vol.37
, pp. 63-66
-
-
Rozniecki, J.J.1
Hauser, S.L.2
Stein, M.3
Lincoln, R.4
Theoharides, T.C.5
-
115
-
-
0033982381
-
Proteinase-activated receptors (PARs): Activation of PAR1 and PAR2 by a proteolytic fragment of the neuronal growth associated protein B-50/GAP-43
-
Hollenberg, M. D., Saifeddine, M. & Zwiers, H. Proteinase-activated receptors (PARs): activation of PAR1 and PAR2 by a proteolytic fragment of the neuronal growth associated protein B-50/GAP-43. Can. J. Physiol. Pharmacol. 78, 81-85 (2000).
-
(2000)
Can. J. Physiol. Pharmacol.
, vol.78
, pp. 81-85
-
-
Hollenberg, M.D.1
Saifeddine, M.2
Zwiers, H.3
-
116
-
-
0028021308
-
Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho
-
Jalink, K. et al. Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho. J. Cell. Biol. 126, 801-810 (1994).
-
(1994)
J. Cell. Biol.
, vol.126
, pp. 801-810
-
-
Jalink, K.1
-
117
-
-
0033532076
-
Thrombin induces proteinase-activated receptor-1 gene expression in endothelial cells via activation of Gi-linked Ras/mitogen-activated protein kinase pathway
-
Ellis, C. A. et al. Thrombin induces proteinase-activated receptor-1 gene expression in endothelial cells via activation of Gi-linked Ras/mitogen-activated protein kinase pathway J. Biol. Chem. 274, 13718-13727 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 13718-13727
-
-
Ellis, C.A.1
|