The metabotropic glutamate receptor mGluR5 induces calcium oscillations in cultured astrocytes via protein kinase C phosphorylation

Journal of Neurochemistry

Volumn 69, Issue 4, 1997, Pages 1467-1475

  Nakahara, Kiyoshi ^a   Okada, Masamichi ^b   Nakanishi, Shigetada ^a  

^a KYOTO UNIVERSITY   (Japan)

^b ASTELLAS PHARMA INC   (Japan)

Author keywords

Astrocyte; Calcium oscillation; Metabotropic glutamate receptor; Protein kinase C; Protein phosphorylation

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; BASIC FIBROBLAST GROWTH FACTOR; BISINDOLYLMALEIMIDE; CALCIUM ION; EPIDERMAL GROWTH FACTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR AGONIST; GROWTH FACTOR; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PROTEIN KINASE C ACTIVATOR; PROTEIN KINASE C INHIBITOR; TRANSFORMING GROWTH FACTOR ALPHA;

ANIMAL CELL; ARTICLE; ASTROCYTE; CALCIUM CELL LEVEL; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT;

ANIMALIA;

EID: 0030886438     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.69041467.x     Document Type: Article

References (52)

1. 2+ signal transduction. J. Biol. Chem. 267, 13361-13368.
2. Berridge M. J. (1991) Cytoplasmic calcium oscillations: a two pool model. Cell Calcium 12, 63-72.
3. Berridge M. J. (1993) Inositol trisphosphate and calcium signalling. Nature 361, 315-325.
4. Bessho Y., Nawa H., and Nakanishi S. (1993) Glutamate and quisqualate regulate expression of metabotropic glutamate receptor mRNA in cultured cerebellar granule cells. J. Neurochem. 60, 253-259.
5. Bird G. S. J., Rossier M. F., Obie J. F., and Putney J. W. Jr. (1993) Sinusoidal oscillations in intracellular calcium requiring negative feedback by protein kinase C. J. Biol. Chem. 268, 8425-8428.
6. Bliss T. V. P. and Collingridge G. L. (1993) A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361, 31-39.
7. Brock T. A., Rittenhouse S. E., Powers C. W., Ekstein L. S., Gimbrone M. A. Jr., and Alexander R. W. (1985) Phorbol ester and 1-oleoyl-2-acetylglycerol inhibit angiotensin activation of phospholipase C in cultured vascular smooth muscle, J. Biol. Chem. 260, 14158-14162.
8. Castagna M., Takai Y., Kaibuchi K., Sano K., Kikkawa U., and Nishizuka Y. (1982) Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. J. Biol. Chem. 257, 7847-7851.
9. Chavis P., Fagni L., Lansman J. B., and Bockaert J. (1996) Functional coupling between ryanodine receptors and L-type calcium channels in neurons. Nature 382, 719-722.
10. Choi D. W. and Rothman S. M. (1990) The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annu. Rev. Neurosci. 13, 171-182.
11. Clapham D. E. (1995) Calcium signaling. Cell 80, 259-268.
12. Cobbold P. H., Sanchez-Bueno A., and Dixon C. J. (1991) The hepatocyte calcium oscillator. Cell Calcium 12, 87-95.
13. 2+ waves in astrocytes. Cell Calcium 12, 185-204.
14. Cornell-Bell A. H., Finkbeiner S. M., Cooper M. S., and Smith S. J. (1990a) Glutamate induces calcium waves in cultured astrocytes: long-range glial signaling. Science 247, 470-473.
15. Cornell-Bell A. H., Thomas P. G., and Smith S. J. (1990b) The excitatory neurotransmitter glutamate causes filopodia formation in cultured hippocampal astrocytes. Glia 3, 322-334.
16. Cornell-Bell A. H., Magge S., and During M. (1992) Human cortical astrocytes from hyperexcitable epileptic foci are themselves hyperexcitable, in Excitatory Amino Acids (Simon R. P., ed), pp. 273-277. Thieme Medical, New York.
17. 2+. Nature 316, 541-542.
18. Dani J. W., Chernjavsky A., and Smith S. J. (1992) Neuronal activity triggers calcium waves in hippocampal astrocyte networks. Neuron 8, 429-440.
19. Davis P. D., Hill C. H., Lawton G., Nixon J. S., Wilkinson S. E., Hurst S. A., Keech E., and Turner S. E. (1992) Inhibitors of protein kinase C. 1. 2,3-Bisarylmaleimides. J. Med. Chem. 35, 177-184.
20. 2+ mobilization in cultured rat cerebellar cells: astrocytes are activated by t-ACPD. Eur. J. Neurosci. 3, 1146-1154.
21. Dupont G. and Goldbeter A. (1992) Oscillations and waves of cytosolic calcium: insights from theoretical models. Bioessays 14, 485-493.
22. Eng L. F., Yu A. C. H., and Lee Y. L. (1992) Astrocytic response to injury. Prog. Brain Res. 94, 353-365.
23. Evans R. H., Francis A. A., Jones A. W., Smith D. A. S., and Watkins J. C. (1982) The effects of a series of ω-phosphonic α-carboxylic amino acids on electrically evoked and excitant amino acid-induced responses in isolated spinal cord preparations. Br. J. Pharmacol. 75, 65-75.
24. 2+ influx into astrocytes. Proc. Natl. Acad. Sci. USA 87, 3454-3458.
25. Hatten M. E., Liem R. K. H., Shelanski M. L., and Mason C. A. (1991) Astroglia in CNS injury. Glia 4, 233-243.
26. Hollmann M. and Heinemann S. (1994) Cloned glutamate receptors. Annu. Rev. Neurosci. 17, 31-108.
27. Holzwarth J. A., Gibbons S. J., Brorson J. R., Philipson L. H., and Miller R. J. (1994) Glutamate receptor agonists stimulate diverse calcium responses in different types of cultured rat cortical glial cells. J. Neurosci. 14, 1879-1891.
28. Honoré T., Davies S. N., Drejer J., Fletcher E. J., Jacobsen P., Lodge D., and Nielsen F. E. (1988) Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists. Science 241, 701-703.
29. Ishihara H., Martin B. L., Brautigan D. L., Karaki H., Ozaki H., Kato Y., Fusetani N., Watabe S., Hashimoto K., Uemura D., and Hartshorne D. J. (1989) Calyculin A and okadaic acid: inhibitors of protein phosphatase activity. Biochem. Biophys. Res. Commun. 159, 871-877.
30. Jensen A. M. and Chiu S. Y. (1990) Fluorescence measurement of changes in intracellular calcium induced by excitatory amino acids in cultured cortical astrocytes. J. Neurosci. 10, 1165-1175.
31. Kawabata S., Tsutsumi R., Kohara A., Yamaguchi T., Nakanishi S., and Okada M. (1996) Control of calcium oscillations by phosphorylation of metabotropic glutamate receptors. Nature 383, 89-92.
32. Liu J., Farmer J. D. Jr., Lane W. S., Friedman J., Weissman I., and Schreiber S. L. (1991) Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 66, 807-815.
33. Masu M., Tanabe Y., Tsuchida K., Shigemoto R., and Nakanishi S. (1991) Sequence and expression of a metabotropic glutamate receptor. Nature 349, 760-765.
34. Mayer M. L. and Westbrook G. L. (1987) The physiology of excitatory amino acids in the vertebrate central nervous system. Prog. Neurobiol. 28, 197-276.
35. Miller S., Romano C., and Cotman C. W. (1995) Growth factor upregulation of a phosphoinositide-coupled metabotropic glutamate receptor in cortical astrocytes. J. Neurosci. 15, 6103-6109.
36. Minakami R., Katsuki F., and Sugiyama H. (1993) A variant of metabotropic glutamate receptor subtype 5: an evolutionally conserved insertion with no termination codon. Biochem. Biophys. Res. Commun. 194, 622-627.
37. Nakanishi S. (1992) Molecular diversity of glutamate receptors and implications for brain function. Science 258, 597-603.
38. Nakanishi S. (1994) Metabotropic glutamate receptors: synaptic transmission, modulation, and plasticity. Neuron 13, 1031-1037.
39. Nakanishi S. and Masu M. (1994) Molecular diversity and functions of glutamate receptors. Annu. Rev. Biophys. Biomol. Struct. 23, 319-348.
40. Palmer E., Monaghan D. T., and Cotman C. W. (1989) trans-ACPD, a selective agonist of the phosphoinositide-coupled excitatory amino acid receptor. Eur. J. Pharmacol. 166, 585-587.
41. Pin J. P. and Duvoisin R. (1995) The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34, 1-26.
42. Pin J. P., Waeber C., Prezeau L., Bockaert J., and Heinemann S. F. (1992) Alternative splicing generates metabotropic glutamate receptors inducing different patterns of calcium release in Xenopus oocytes. Proc. Natl. Acad. Sci. USA 89, 10331-10335.
43. i. Glia 13, 101-112.
44. Saugstad J. A., Segerson T. P., and Westbrook G. L. (1995) L-2-Amino-3-phosphonopropionic acid competitively antagonizes metabotropic glutamate receptors 1 α and 5 in Xenopus oocytes. Eur. J. Pharmacol. 289, 395-397.
45. Seroogy K. B., Lundgren K. H., Lee D. C., Guthrie K. M., and Gall C. M. (1993) Cellular localization of transforming growth factor-α mRNA in rat forebrain. J. Neurochem. 60, 1777-1782.
46. Shigemoto R., Nomura S., Ohishi H., Sugihara H., Nakanishi S., and Mizuno N. (1993) Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain. Neurosci. Lett. 163, 53-57.
47. Smith S. J. (1992) Do astrocytes process neural information? Prog. Brain Res. 94, 119-136.
48. Somogyi R. and Stucki J. W. (1991) Hormone-induced calcium oscillations in liver cells can be explained by a simple one pool model. J. Biol. Chem. 266, 11068-11077.
49. Tanabe Y., Masu M., Ishii T., Shigemoto R., and Nakanishi S. (1992) A family of metabotropic glutamate receptors. Neuron 8, 169-179.
50. 2+/calmodulin-dependent protein kinase II. J. Biol. Chem. 265, 4315-4320.
51. Toullec D., Pianetti P., Coste H., Bellevergue P., Grand-Perret T., Ajakane M., Baudet V., Boissin P., Boursier E., Loriolle F., Duhamel L., Charon D., and Kirilovsky J. (1991) The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J. Biol. Chem. 266, 15771-15781.
52. Woods N. M., Cuthbertson K. S. R., and Cobbold P. H. (1987) Phorbol-ester-induced alterations of free calcium ion transients in single rat hepatocytes. Biochem. J. 246, 619-623.