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Volumn 69, Issue 5, 1997, Pages 1890-1896

Protease-activated receptor-2 (PAR-2) is present in the rat hippocampus and is associated with neurodegeneration

Author keywords

Fura 2; Immunocytochemistry; Neuronal survival; Reverse transcriptase polymerase chain reaction

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; HEXAPEPTIDE; PROTEINASE; SYNTHETIC PEPTIDE; THROMBIN; THROMBIN RECEPTOR;

EID: 0030774851     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.69051890.x     Document Type: Article
Times cited : (98)

References (29)
  • 3
    • 0000483993 scopus 로고
    • Immunohistochemical detection of DNA topoisomerases IIα and IIβ compared with detection of Ki-67, a marker of cellular proliferation, in human tumors
    • D'Andrea M. R., Farber P. A., and Foglesong P. D. (1994) Immunohistochemical detection of DNA topoisomerases IIα and IIβ compared with detection of Ki-67, a marker of cellular proliferation, in human tumors. Appl. Immunohistochem. 2, 177-185.
    • (1994) Appl. Immunohistochem. , vol.2 , pp. 177-185
    • D'Andrea, M.R.1    Farber, P.A.2    Foglesong, P.D.3
  • 4
    • 0024424624 scopus 로고
    • Nature of thrombin-induced sustained increase in cytosolic calcium concentration in cultured endothelial cells
    • Goligorsky M. S., Menton D. N., Laszlo A., and Lum H. (1989) Nature of thrombin-induced sustained increase in cytosolic calcium concentration in cultured endothelial cells. J. Biol. Chem. 264, 16771-16775.
    • (1989) J. Biol. Chem. , vol.264 , pp. 16771-16775
    • Goligorsky, M.S.1    Menton, D.N.2    Laszlo, A.3    Lum, H.4
  • 5
    • 0021895138 scopus 로고
    • A new generation of calcium indicators with greatly improved fluorescence properties
    • Grynkiewicz G., Poenie M., and Tsien R. Y. (1985) A new generation of calcium indicators with greatly improved fluorescence properties. J. Biol. Chem. 260, 3440-3450.
    • (1985) J. Biol. Chem. , vol.260 , pp. 3440-3450
    • Grynkiewicz, G.1    Poenie, M.2    Tsien, R.Y.3
  • 6
    • 0030044693 scopus 로고    scopus 로고
    • Proteinase-activated receptor-2 in rat aorta: Structural requirements for agonist activity of receptor-activating peptides
    • Hollenberg M. D., Saifeddine M., and Al-Ani B. (1996) Proteinase-activated receptor-2 in rat aorta: structural requirements for agonist activity of receptor-activating peptides. Mol. Pharmacol. 49, 229-233.
    • (1996) Mol. Pharmacol. , vol.49 , pp. 229-233
    • Hollenberg, M.D.1    Saifeddine, M.2    Al-Ani, B.3
  • 7
    • 0029979497 scopus 로고    scopus 로고
    • Evidence for the presence of a proteinase-activated receptor distinct from the thrombin receptor in vascular endothelial cells
    • Hwa J. J., Ghibaudi L., Williams P., Chintala M., Zhang R., Chatterjee M., and Sybertz E. (1996) Evidence for the presence of a proteinase-activated receptor distinct from the thrombin receptor in vascular endothelial cells. Circ. Res. 78, 581-588.
    • (1996) Circ. Res. , vol.78 , pp. 581-588
    • Hwa, J.J.1    Ghibaudi, L.2    Williams, P.3    Chintala, M.4    Zhang, R.5    Chatterjee, M.6    Sybertz, E.7
  • 9
    • 0028595972 scopus 로고
    • The role of mast cells in inflammatory reactions of the airways, skin and intestine
    • Marshall J. S. and Bienenstock J. (1994) The role of mast cells in inflammatory reactions of the airways, skin and intestine. Curr. Opin. Immunol. 6, 853-859.
    • (1994) Curr. Opin. Immunol. , vol.6 , pp. 853-859
    • Marshall, J.S.1    Bienenstock, J.2
  • 10
    • 0023798578 scopus 로고
    • Isolated hippocampal neurons in cryopreserved long-term cultures: Development of neuroarchitecture and sensitivity to NMDA
    • Mattson M. P. and Kater S. B. (1988) Isolated hippocampal neurons in cryopreserved long-term cultures: development of neuroarchitecture and sensitivity to NMDA. Int. J. Dev. Neurosci. 6, 439-452.
    • (1988) Int. J. Dev. Neurosci. , vol.6 , pp. 439-452
    • Mattson, M.P.1    Kater, S.B.2
  • 11
    • 0026570528 scopus 로고
    • β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
    • Mattson M. P., Cheng B., Davis D., Bryant K., Lieberburg I., and Rydel R. E. (1992) β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J. Neurosci. 12, 376-389.
    • (1992) J. Neurosci. , vol.12 , pp. 376-389
    • Mattson, M.P.1    Cheng, B.2    Davis, D.3    Bryant, K.4    Lieberburg, I.5    Rydel, R.E.6
  • 12
    • 0029175202 scopus 로고
    • Calcium, free radicals and excitotoxic neuronal death in primary cell culture
    • Mattson M. P., Barger S. W., Begley J., and Mark R. J. (1995) Calcium, free radicals and excitotoxic neuronal death in primary cell culture. Methods Cell Biol. 46, 187-216.
    • (1995) Methods Cell Biol. , vol.46 , pp. 187-216
    • Mattson, M.P.1    Barger, S.W.2    Begley, J.3    Mark, R.J.4
  • 13
    • 0030003829 scopus 로고    scopus 로고
    • The proteinase-activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cells. Molecular characterization and evidence for functional coupling to the thrombin receptor
    • Mirza H., Yatsula V., and Bahou W. F. (1996) The proteinase-activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cells. Molecular characterization and evidence for functional coupling to the thrombin receptor. J. Clin. Invest. 97, 1705-1714.
    • (1996) J. Clin. Invest. , vol.97 , pp. 1705-1714
    • Mirza, H.1    Yatsula, V.2    Bahou, W.F.3
  • 17
    • 0029113121 scopus 로고
    • Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2
    • Nystedt S., Emilsson K., Larsson A.-K., Strombeck B., and Sundelin J. (1995) Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2. Eur. J. Biochem. 232, 84-89.
    • (1995) Eur. J. Biochem. , vol.232 , pp. 84-89
    • Nystedt, S.1    Emilsson, K.2    Larsson, A.-K.3    Strombeck, B.4    Sundelin, J.5
  • 18
    • 15844401726 scopus 로고    scopus 로고
    • The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. Comparison with the thrombin receptor
    • Nystedt S., Ramakrishnan V., and Sundelin J. (1996) The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. Comparison with the thrombin receptor. J. Biol. Chem. 271, 14910-14915.
    • (1996) J. Biol. Chem. , vol.271 , pp. 14910-14915
    • Nystedt, S.1    Ramakrishnan, V.2    Sundelin, J.3
  • 19
    • 0029914487 scopus 로고    scopus 로고
    • Thrombin attenuates neuronal cell death and modulates astrocyte reactivity induced by β-amyloid in vitro
    • Pike C. J., Vaughan P. J., Cunningham D. D., and Cotman C. W. (1996) Thrombin attenuates neuronal cell death and modulates astrocyte reactivity induced by β-amyloid in vitro. J. Neurochem. 66, 1374-1382.
    • (1996) J. Neurochem. , vol.66 , pp. 1374-1382
    • Pike, C.J.1    Vaughan, P.J.2    Cunningham, D.D.3    Cotman, C.W.4
  • 23
    • 0029134929 scopus 로고
    • Opposing actions of thrombin and protease nexin-1 on amyloid β-peptide toxicity and accumulation of peroxides and calcium in hippocampal neurons
    • Smith-Swintosky V. L., Zimmer S., Fenton J. W. II, and Mattson M. P. (1995b) Opposing actions of thrombin and protease nexin-1 on amyloid β-peptide toxicity and accumulation of peroxides and calcium in hippocampal neurons. J. Neurochem. 65, 1415-1418.
    • (1995) J. Neurochem. , vol.65 , pp. 1415-1418
    • Smith-Swintosky, V.L.1    Zimmer, S.2    Fenton II, J.W.3    Mattson, M.P.4
  • 24
    • 0026441167 scopus 로고
    • Thrombin receptor 14-amino acid peptide binds to endothelial cells and stimulates calcium transients
    • Tiruppathi C., Lum H., Andersen T. T., Fenton J. W., and Malik A. B. (1992) Thrombin receptor 14-amino acid peptide binds to endothelial cells and stimulates calcium transients. Am. J. Physiol. 263, L595-L601.
    • (1992) Am. J. Physiol. , vol.263
    • Tiruppathi, C.1    Lum, H.2    Andersen, T.T.3    Fenton, J.W.4    Malik, A.B.5
  • 25
    • 0027232790 scopus 로고
    • Functional thrombin receptors on lymphoblastoid cells
    • Tordai A., Fenton J. W., Andersen T., and Gelfand E. W. (1993) Functional thrombin receptors on lymphoblastoid cells. J. Immunol. 150, 4876-4886.
    • (1993) J. Immunol. , vol.150 , pp. 4876-4886
    • Tordai, A.1    Fenton, J.W.2    Andersen, T.3    Gelfand, E.W.4
  • 26
    • 0029012029 scopus 로고
    • Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults
    • Vaughan P. J., Pike C. J., Cotman C. W., and Cunningham D. D. (1995) Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults. J. Neurosci. 15, 5389-5401.
    • (1995) J. Neurosci. , vol.15 , pp. 5389-5401
    • Vaughan, P.J.1    Pike, C.J.2    Cotman, C.W.3    Cunningham, D.D.4
  • 27
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism
    • Vu T.-K. H., Wheaton V. I., Hung D. T., and Coughlin S. R. (1991) Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism. Cell 64, 1057-1068.
    • (1991) Cell , vol.64 , pp. 1057-1068
    • Vu, T.-K.H.1    Wheaton, V.I.2    Hung, D.T.3    Coughlin, S.R.4
  • 28
    • 0028914068 scopus 로고
    • Cellular localization of thrombin receptor mRNA in rat brain: Expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA
    • Weinstein J. R., Gold S, J., Cunningham D. D., and Gall C. M. (1995) Cellular localization of thrombin receptor mRNA in rat brain: expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA. J. Neurosci. 15, 2906-2919.
    • (1995) J. Neurosci. , vol.15 , pp. 2906-2919
    • Weinstein, J.R.1    Gold, S.J.2    Cunningham, D.D.3    Gall, C.M.4
  • 29
    • 0026802136 scopus 로고
    • Molecular cloning of the rat vascular smooth muscle thrombin receptor: Evidence for in vitro regulation by basic fibroblast growth factor
    • Zhong C., Hayzer D. J., Corson M. A., and Runge M. S. (1992) Molecular cloning of the rat vascular smooth muscle thrombin receptor: evidence for in vitro regulation by basic fibroblast growth factor. J. Biol. Chem. 267, 16975-16979.
    • (1992) J. Biol. Chem. , vol.267 , pp. 16975-16979
    • Zhong, C.1    Hayzer, D.J.2    Corson, M.A.3    Runge, M.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.