Stepwise assembly of a glucocorticoid receptor·hsp90 heterocomplex resolves two sequential ATP-dependent events involving first hsp70 and then hsp90 in opening of the steroid binding pocket

Journal of Biological Chemistry

Volumn 275, Issue 24, 2000, Pages 18054-18060

  Morishima, Yoshihiro ^a   Murphy, Patrick J M ^a   Li, Da Pei ^b   Sanchez, Edwin R ^b   Pratt, William B ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CHAPERONE; GLUCOCORTICOID RECEPTOR; HEAT SHOCK PROTEIN 40; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; PROTEIN P23; STEROID;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; RETICULOCYTE;

ADENOSINE TRIPHOSPHATE; ANIMALS; BACULOVIRIDAE; BINDING SITES; CELLS, CULTURED; HSP70 HEAT-SHOCK PROTEINS; HSP90 HEAT-SHOCK PROTEINS; MACROMOLECULAR SUBSTANCES; MICE; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; RECEPTORS, GLUCOCORTICOID; SPODOPTERA;

HUMULUS;

EID: 0034674783     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M000434200     Document Type: Article

References (32)

1. Pratt, W. B., and Toft, D. O. (1997) Endocr. Rev. 18, 306-360
2. Bresnick. E. H., Dalman, F. C., Sanchez, E. R., and Pratt, W. B. (1989) J. Biol. Chem. 264, 4992-4997
3. Hutchison, K. A., Czar, M. J., Scherrer, L. C., and Pratt, W. B. (1992) J. Biol. Chem. 267, 14047-14053
4. Stancato, L. F., Silverstein, A. M., Gitler, C., Groner, B., and Pratt, W. B. (1996) J. Biol. Chem. 271, 8831-8836
5. Xu, M., Dittmar, K. D., Giannoukos, G., Pratt, W. B., and Simons, S. S., Jr. (1998) J. Biol. Chem. 273, 13918-13924
6. Giannoukos, G., Silverstein, A. M., Pratt, W. B., and Simons, S. S., Jr. (1999) J. Biol. Chem. 274, 36527-36536
7. Smith, D. F., Schowalter, D. B., Kost, S. L., and Toft, D. O. (1990) Mol. Endocrinol. 4, 1704-1711
8. Scherrer, L. C., Dalman, F. C., Massa, E., Meshinchi, S., and Pratt, W. B. (1990) J. Biol. Chem. 265, 21397-21400
9. Stancato, L. F., Hutchison, K. A., Krishna, P., and Pratt, W. B. (1996) Biochemistry 35, 554-561
10. Dittmar, K. D., Hutchison, K. A., Owens-Grillo, J. K., and Pratt, W. B. (1996) J. Biol. Chem. 271, 12833-12839
11. Dittmar, K. D., and Pratt, W. B. (1997) J. Biol. Chem. 272, 13047-13054
12. Dittmar, K. D., Demady, D. R., Stancato, L. F., Krishna, P., and Pratt, W. B. (1997) J. Biol. Chem. 272, 21213-21220
13. Dittmar, K. D., Banach, M., Galigniana, M. D., and Pratt, W. B. (1998) J. Biol. Chem. 273, 7358-7366
14. Kosano, H., Stensgard, B., Charlesworth, M. C., McMahon, N., and Toft, D. (1998) J. Biol. Chem. 273, 32973-32979
15. Toft, D. O. (1998) Trends Endocrinol. Metab. 9, 238-243
16. Pratt, W. B., and Dittmar, K. D. (1998) Trends Endocrinol. Metab. 9, 244-252
17. Morishima, Y., Kanelakis, K. C., Silverstein, A. M., Dittmar, K. D., Estrada, L., and Pratt, W. B. (2000) J. Biol. Chem. 275, 6894-6900
18. Chen, S., Prapapanich, V., Rimerman, R. A., Honoré, B., and Smith, D. F. (1996) Mol. Endocrinol. 10, 682-693
19. Hartl, F. U. (1996) Nature 381, 571-580
20. Sullivan, W., Stensgard, B., Caucutt, G., Bartha, B., McMahon, N., Alnemri, E. S., Litwack, G., and Toft, D. (1997) J Biol. Chem. 272, 8007-8012
21. Grenert, J. P., Sullivan, W. P., Fadden, P., Maystead, T. A. J., Clark, J., Mimnaugh, E., Krutzsh, H., Ochel, H. J., Schulte, T. W., Sausville, E., Neckers, L. M., and Toft, D. O. (1997) J. Biol. Chem. 272, 23843-23850
22. Grenert, J. P., Johnson, B. D., and Toft, D. O. (1999) J. Biol. Chem. 274, 17525-17533
23. Hutchison, K. A., Dittmar, K. D., and Pratt, W. B. (1994) J. Biol. Chem. 269, 27894-27899
24. Danielsen, M., Northrup, J. P., and Ringold, G. M. (1986) EMBO J. 5, 2513-2522
25. Srinivasan, G., Post, J. F. M., and Thompson, E. B. (1997) J. Steroid Biochem. Mol. Biol. 60, 1-9
26. Johnson, J. L., and Toft, D. O. (1994) J. Biol. Chem. 269, 24989-24993
27. Caplan, A. J., Tsai, J., Casey, P. J., and Douglas, M. G. (1992) J. Biol. Chem. 267, 18890-18895
28. Schumacher, R. J., Hansen, W. J., Freeman, B. C., Alnemri, E., Litwack, G., and Toft, D. O. (1993) Biochemistry 35, 14889-14898
29. Prapapanich, Y., Chen, S., Nair, S. C., Rimerman, R. A., and Smith, D. F. (1996) Mol. Endocrinol. 10, 420-431
30. Srinivasan, G., Patel, N. T., and Thompson, E. B. (1994) Mol. Endocrinol. 8, 189-196
31. Minami, Y., Hohfeld, J., Ohtsuka, K., and Hartl, F. U. (1996) J. Biol. Chem. 271, 19617-19624
32. Silverstein, A. M., Galigniana, M. D., Kanelakis, K. C., Radanyi, C., Renoir, J-M., and Pratt, W. B. (1999) J. Biol. Chem. 274, 36980-36986