Geldanamycin, a heat shock protein 90-binding benzoquinone ansamycin, inhibits steroid-dependent translocation of the glucocorticoid receptor from the cytoplasm to the nucleus

Biochemistry

Volumn 36, Issue 25, 1997, Pages 7776-7785

  Czar, Michael J ^a   Galigniana, Mario D ^a   Silverstein, Adam M ^a   Pratt, William B ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOQUINONE; DEXAMETHASONE; GELDANAMYCIN; GLUCOCORTICOID RECEPTOR; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; IMMUNOPHILIN; PROGESTERONE; RIFABUTIN; STEROID; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; HORMONE RECEPTOR INTERACTION; INTRACELLULAR TRANSPORT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DNA BINDING; PROTEIN TARGETING;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BENZOQUINONES; BIOLOGICAL TRANSPORT; CELL LINE; CELL NUCLEUS; CYTOPLASM; HSP90 HEAT-SHOCK PROTEINS; LACTAMS, MACROCYCLIC; MICE; PROTEIN BINDING; QUINONES; RECEPTORS, GLUCOCORTICOID;

ANIMALIA;

EID: 0030808079     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi970648x     Document Type: Article

References (48)

1. Bodwell, J. E., Orti, E., Coull, J. M., Pappin, D. J. C., Smith, L. I., & Swift, F. (1991) J. Biol. Chem. 266, 7549-7555.
2. Bresnick, E. H., Dalman, F. C., Sanchez, E. R., & Pratt, W. B. (1989) J. Biol. Chem. 264, 4992-4997.
3. Callebaut, I., Renoir, J. M., Lebeau, M. C., Massol, N., Burny, A., Baulieu, E. E., & Mornon, J. P. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 6270-6274.
4. Chandran, U. R., & DeFranco, D. B. (1992) Mol. Endocrinol. 6, 837-844.
5. Chavany, C., Mimnaugh, E., Miller, P., Bitton, R., Nguyen, P., Trepel, J., Whitesell, L., Schnur, R., Moyer, J. D., & Neckers, L. (1996) J. Biol. Chem. 271, 4974-4977.
6. Czar, M. J., Lyons, R. H., Welsh, M. J., Renoir, J. M., & Pratt, W. B. (1995) Mol. Endocrinol. 9, 1549-1560.
7. Dauvois, S., White, R., & Parker, M. G. (1993) J. Cell Sci. 106, 1377-1388.
8. DeFranco, D. B., Madan, A. P., Tang, Y., Chandran, U. R., Xiao, N., & Yang, J. (1995) Vitam. and Horm. (San Diego) 51, 315-338.
9. Guichon-Mantel, A., Lescop, P., Christin-Maitre, S., Loosefelt, H., Perrot-Applanat, M., & Milgrom, E. (1991) EMBO J. 10, 3851-3859.
10. Hu, L. M., Bodwell, J., Hu, J. M., Orti, E., & Munck, A. (1994) J. Biol. Chem. 269, 6571-6577.
11. Hutchison, K. A., Brott, B. K., DeLeon, J. H., Perdew, G. H., Jove, R., & Pratt, W. B. (1992a) J. Biol. Chem. 267, 2902-2908.
12. Hutchison, K. A., Czar, M. J., Scherrer, L. C., & Pratt, W. B. (1992b) J. Biol. Chem. 267, 14047-14053.
13. Johnson, J. L., & Toft, D. O. (1995) Mol. Endocrinol. 9, 670-678.
14. June, C. H., Fletcher, M. C., Ledbetter, J. A., Schieven, G. L., Siegel, N. J., Philips, A. F., & Samelson, L. E. (1990) Proc. Natl. Acad. Sci. U.S.A. 87, 7722-7726.
15. Kang, K. I., Devin, J., Cadepond, F., Jibard, N., Guichon-Mantel, A., Baulieu, E. E., & Catelli, M. G. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 340-344.
16. Lebeau, M. C., Massol, N., Herrick, J., Faber, L. E., Renoir, J. M., Radanyi, C., & Baulieu, E. E. (1992) J. Biol. Chem. 267, 4281-4284.
17. Madan, A. P., & DeFranco, D. B. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 3588-3592.
18. Meshinchi, S., Sanchez, E. R., Martell, K. J., & Pratt, W. B. (1990) J. Biol. Chem. 265, 4863-4870.
19. Orti, E., Bodwell, J. E., & Munck, A. (1992) Endocr. Rev. 13, 105-128.
20. Owens-Grillo, J. K., Hoffmann, K., Hutchison, K. A., Yem, A. W., Deibel, M. R., Handschumacher, R. E., & Pratt, W. B. (1995) J. Biol. Chem. 270, 20479-20484.
21. Owens-Grillo, J. K., Czar, M. J., Hutchison, K. A., Hoffmann, K., Perdew, G. H., & Pratt, W. B. (1996) J. Biol. Chem. 271, 13468-13475.
22. Parsell, D. A., & Lindquist, S. (1993) Annu. Rev. Genet. 27, 437-496.
23. Peattie, D. A., Harding, M. W., Fleming, M. A., De Cenzo, M. T., Lippke, J. A., Livingston, D. J., & Benasutti, M. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 10974-10978.
24. Perrot-Applanat, M., Logeat, F., Groyer-Picard, M. T., & Milgrom, E. (1985) Endocrinology 116, 1473-1484.
25. Perrot-Applanat, M., Groyer-Picard, M. T., Logeat, F., & Milgrom, E. (1986) J. Cell Biol. 102, 1191-1199.
26. Picard, D., & Yamamoto, K. R. (1987) EMBO J. 6, 3333-3340.
27. Pratt, W. B. (1992) BioEssays 14, 841-848.
28. Pratt, W. B. (1993) J. Biol. Chem. 268, 21455-21458.
29. Pratt, W. B., Czar, M. J., Stancato, L. F., & Owens, J. K. (1993) J. Steroid Biochem. Mol. Biol. 46, 269-279.
30. Qi, M., Hamilton, B. J., & DeFranco, D. B. (1989) Mol. Endocrinol. 3, 1279-1288.
31. Raaka, B. M., Finnerty, M., Sun, E., & Samuels, H. H. (1985) J. Biol. Chem. 260, 14009-14015.
32. Scherrer, L. C., Dalman, F. C., Massa, E., Meshinchi, S., & Pratt, W. B. (1990) J. Biol. Chem. 265, 21397-21400.
33. Scherrer, L. C., Picard, D., Massa, E., Harmon, J. M., Simons, S. S., Yamamoto, K. R., & Pratt, W. B. (1993) Biochemistry 32, 5381-5386.
34. Schmitt, J., Pohl, J., & Stunnenberg, H. G. (1993) Gene 132, 267-271.
35. Schulte, T. W., Blagosklonny, M. V., Ingui, C., & Neckers, L. (1995) J. Biol. Chem. 270, 24585-24588.
36. Smith, D. F. (1993) Mol. Endocrinol. 7, 1418-1429.
37. Smith, D. F., Sullivan, W. P., Marion, T. N., Zaitsu, K., Madden, B., McCormick, D. J., & Toft, D. O. (1993) Mol. Cell. Biol. 13, 869-876.
38. Smith, D. F., Whitesell, L., Nair, S. C., Chen, S., Prapapanich, V., & Rimerman, R. A. (1995) Mol. Cell. Biol. 15, 6804-6812.
39. Stancato, L. F., Chow, Y. H., Hutchison, K. A., Perdew, G. H., Jove, R., & Pratt, W. B. (1993) J. Biol. Chem. 268, 21711-21716.
40. Stancato, L. F., Hutchison, K. A., Krishna, P., & Pratt, W. B. (1996) Biochemistry 35, 554-561.
41. Tienrungroj, W., Sanchez, E. R., Housley, P. R., Harrison, R. W., & Pratt, W. B. (1987) J. Biol. Chem. 262, 17342-17349.
42. Uehara, Y., Murakami, Y., Mizuno, S., & Kawai, S. (1988) Virology 164, 294-298.
43. Urda, L. A., Yen, P. M., Simons, S. S., & Harmon, J. M. (1989) Mol. Endocrinol. 3, 251-260.
44. Welsh, M. J. (1983) Methods Enzymol. 102, 110-121.
45. Whitesell, L., & Cook, P. (1996) Mol. Endocrinol. 10, 705-712.
46. Whitesell, L., Shifrin, S. D., Schwab, G., & Neckers, L. M. (1992) Cancer Res. 52, 1721-1728.
47. Whitesell, L., Mimnaugh, E. G., De Costa, B., Myers, C. E., & Neckers, L. M. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 8324-8328.
48. Yang, J., & DeFranco, D. B. (1996) Mol. Endocrinol. 10, 3-13.