-
1
-
-
0035843243
-
Brain tumors
-
L. M. DeAngelis: Brain tumors. N Engl J Med 344, 114-123. (2001)
-
(2001)
N Engl J Med
, vol.344
, pp. 114-123
-
-
DeAngelis, L.M.1
-
2
-
-
0027516695
-
Meta-analysis of radiation therapy with and without adjuvant chemotherapy for malignant gliomas in adults
-
H. A. Fine, K. B. Dear, J. S. Loeffler, P. M. Black & G. P. Canellos: Meta-analysis of radiation therapy with and without adjuvant chemotherapy for malignant gliomas in adults. Cancer 71, 2585-2597. (1993)
-
(1993)
Cancer
, vol.71
, pp. 2585-2597
-
-
Fine, H.A.1
Dear, K.B.2
Loeffler, J.S.3
Black, P.M.4
Canellos, G.P.5
-
3
-
-
0034090144
-
Biology and treatment of malignant glioma
-
M. D. Prados & V. Levin: Biology and treatment of malignant glioma. Semin Oncol 27, 1-10. (2000)
-
(2000)
Semin Oncol
, vol.27
, pp. 1-10
-
-
Prados, M.D.1
Levin, V.2
-
4
-
-
0033081691
-
Causes of drug resistance and novel therapeutic opportunities for the treatment of glioblastoma
-
M. Nagane, H. J. Huang & W. K. Cavenee: Causes of drug resistance and novel therapeutic opportunities for the treatment of glioblastoma. Drug Resist Updat 2, 30-37. (1999)
-
(1999)
Drug Resist Updat
, vol.2
, pp. 30-37
-
-
Nagane, M.1
Huang, H.J.2
Cavenee, W.K.3
-
6
-
-
0025896416
-
Antineoplastic drug resistance in brain tumors
-
P. C. Phillips: Antineoplastic drug resistance in brain tumors. Neurol Clin 9, 383-404. (1991)
-
(1991)
Neurol Clin
, vol.9
, pp. 383-404
-
-
Phillips, P.C.1
-
7
-
-
0016719486
-
Isolation and structure of urogastrone and its relationship to epidermal growth factor
-
H. Gregory: Isolation and structure of urogastrone and its relationship to epidermal growth factor. Nature 257, 325-327. (1975)
-
(1975)
Nature
, vol.257
, pp. 325-327
-
-
Gregory, H.1
-
8
-
-
0019304894
-
Sarcoma growth factor from mouse sarcoma virus-transformed cells. Purification by binding and elution from epidermal growth factor receptor-rich cells
-
J. E. De Larco, R. Reynolds, K. Carlberg, C. Engle & G. J. Todaro: Sarcoma growth factor from mouse sarcoma virus-transformed cells. Purification by binding and elution from epidermal growth factor receptor-rich cells. J Biol Chem 255, 3685-3690. (1980)
-
(1980)
J Biol Chem
, vol.255
, pp. 3685-3690
-
-
De Larco, J.E.1
Reynolds, R.2
Carlberg, K.3
Engle, C.4
Todaro, G.J.5
-
9
-
-
0000276099
-
Amphiregulin: A bifunctional growth-modulating glycoprotein produced by the phorbol 12-myristate 13-acetate-treated human breast adenocarcinoma cell line MCF-7
-
M. Shoyab, V. L. McDonald, J. G. Bradley & G. J. Todaro: Amphiregulin: a bifunctional growth-modulating glycoprotein produced by the phorbol 12-myristate 13-acetate-treated human breast adenocarcinoma cell line MCF-7. Proc Natl Acad Sci U S A 85, 6528-6532. (1988)
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 6528-6532
-
-
Shoyab, M.1
McDonald, V.L.2
Bradley, J.G.3
Todaro, G.J.4
-
10
-
-
0025904265
-
A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF
-
S. Higashiyama, J. A. Abraham, J. Miller, J. C. Fiddes & M. Klagsbrun: A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF. Science 251, 936-939. (1991)
-
(1991)
Science
, vol.251
, pp. 936-939
-
-
Higashiyama, S.1
Abraham, J.A.2
Miller, J.3
Fiddes, J.C.4
Klagsbrun, M.5
-
11
-
-
0027400724
-
Betacellulin: A mitogen from pancreatic beta cell tumors
-
Y. Shing, G. Christofori, D. Hanahan, Y. Ono, R. Sasada, K. Igarashi & J. Folkman: Betacellulin: a mitogen from pancreatic beta cell tumors. Science 259, 1604-1607. (1993)
-
(1993)
Science
, vol.259
, pp. 1604-1607
-
-
Shing, Y.1
Christofori, G.2
Hanahan, D.3
Ono, Y.4
Sasada, R.5
Igarashi, K.6
Folkman, J.7
-
12
-
-
0029561565
-
Molecular cloning of mouse epiregulin, a novel epidermal growth factor- Related protein, expressed in the early stage of development
-
H. Toyoda, T. Komurasaki, Y. Ikeda, M. Yoshimoto & S. Morimoto: Molecular cloning of mouse epiregulin, a novel epidermal growth factor- related protein, expressed in the early stage of development. FEBS Lett 377, 403-407. (1995)
-
(1995)
FEBS Lett
, vol.377
, pp. 403-407
-
-
Toyoda, H.1
Komurasaki, T.2
Ikeda, Y.3
Yoshimoto, M.4
Morimoto, S.5
-
13
-
-
0022388709
-
Purification and characterization of vaccinia virus growth factor
-
P. Stroobant, A. P. Rice, W. J. Gullick, D. J. Cheng, I. M. Kerr & M. D. Waterfield: Purification and characterization of vaccinia virus growth factor. Cell 42, 383-393. (1985)
-
(1985)
Cell
, vol.42
, pp. 383-393
-
-
Stroobant, P.1
Rice, A.P.2
Gullick, W.J.3
Cheng, D.J.4
Kerr, I.M.5
Waterfield, M.D.6
-
14
-
-
0030771026
-
Signal transduction pathways and their relevance in human astrocytomas
-
M. M. Feldkamp, N. Lau & A. Guha: Signal transduction pathways and their relevance in human astrocytomas. J Neurooncol 35, 223-248. (1997)
-
(1997)
J Neurooncol
, vol.35
, pp. 223-248
-
-
Feldkamp, M.M.1
Lau, N.2
Guha, A.3
-
16
-
-
0033133990
-
The PIK-related kinases intercept conventional signaling pathways
-
F. G. Kuruvilla & S. L. Schreiber: The PIK-related kinases intercept conventional signaling pathways. Chem Biol 6, R129-136. (1999)
-
(1999)
Chem Biol
, vol.6
-
-
Kuruvilla, F.G.1
Schreiber, S.L.2
-
17
-
-
0035859956
-
p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD
-
H. Harada, J. S. Andersen, M. Mann, N. Terada & S. J. Korsmeyer: p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD. Proc Natl Acad Sci U S A 98, 9666-9670. (2001)
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 9666-9670
-
-
Harada, H.1
Andersen, J.S.2
Mann, M.3
Terada, N.4
Korsmeyer, S.J.5
-
18
-
-
0034722888
-
The rapamycin-sensitive signal transduction pathway as a target for cancer therapy
-
M. Hidalgo & E. K. Rowinsky: The rapamycin-sensitive signal transduction pathway as a target for cancer therapy. Oncogene 19, 6680-6686. (2000)
-
(2000)
Oncogene
, vol.19
, pp. 6680-6686
-
-
Hidalgo, M.1
Rowinsky, E.K.2
-
19
-
-
0035312747
-
Regulation of translation initiation by FRAP/mTOR
-
A. C. Gingras, B. Raught & N. Sonenberg: Regulation of translation initiation by FRAP/mTOR. Genes Dev 15, 807-826. (2001)
-
(2001)
Genes Dev
, vol.15
, pp. 807-826
-
-
Gingras, A.C.1
Raught, B.2
Sonenberg, N.3
-
20
-
-
0032053709
-
Mechanisms and consequences of activation of protein kinase B/Akt
-
J. Downward: Mechanisms and consequences of activation of protein kinase B/Akt. Curr Opin Cell Biol 10, 262-267. (1998)
-
(1998)
Curr Opin Cell Biol
, vol.10
, pp. 262-267
-
-
Downward, J.1
-
21
-
-
0031921230
-
Epidermal growth factor induces cyclin D1 in a human prostate cancer cell line
-
J. E. Perry, M. E. Grossmann & D. J. Tindall: Epidermal growth factor induces cyclin D1 in a human prostate cancer cell line. Prostate 35, 117-124. (1998)
-
(1998)
Prostate
, vol.35
, pp. 117-124
-
-
Perry, J.E.1
Grossmann, M.E.2
Tindall, D.J.3
-
22
-
-
0033580853
-
Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. Requirement for Akt activation
-
S. Gibson, S. Tu, R. Oyer, S. M. Anderson & G. L. Johnson: Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. Requirement for Akt activation. J Biol Chem 274, 17612-17618. (1999)
-
(1999)
J Biol Chem
, vol.274
, pp. 17612-17618
-
-
Gibson, S.1
Tu, S.2
Oyer, R.3
Anderson, S.M.4
Johnson, G.L.5
-
23
-
-
0036479531
-
Regulation of cell number by MAPK-dependent control of apoptosis: A mechanism for trophic survival signaling
-
A. Bergmann, M. Tugentman, B. Z. Shilo & H. Steller: Regulation of cell number by MAPK-dependent control of apoptosis: a mechanism for trophic survival signaling. Dev Cell 2, 159-170. (2002)
-
(2002)
Dev Cell
, vol.2
, pp. 159-170
-
-
Bergmann, A.1
Tugentman, M.2
Shilo, B.Z.3
Steller, H.4
-
24
-
-
0032931508
-
Contribution of phosphatidylinositol 3-kinase to radiation resistance in human melanoma cells
-
M. Krasilnikov, V. Adler, S. Y. Fuchs, Z. Dong, A. Haimovitz-Friedman, M. Herlyn & Z. Ronai: Contribution of phosphatidylinositol 3-kinase to radiation resistance in human melanoma cells. MoL Carcinog 24, 64-69. (1999)
-
(1999)
MoL Carcinog
, vol.24
, pp. 64-69
-
-
Krasilnikov, M.1
Adler, V.2
Fuchs, S.Y.3
Dong, Z.4
Haimovitz-Friedman, A.5
Herlyn, M.6
Ronai, Z.7
-
25
-
-
0034604041
-
PI-3-kinase is an essential anti-apoptotic effector in the proliferative response of primary human epithelial cells to mutant RAS
-
V. Gire, C. Marshall & D. Wynford-Thomas: PI-3-kinase is an essential anti-apoptotic effector in the proliferative response of primary human epithelial cells to mutant RAS. Oncogene 19, 2269-2276. (2000)
-
(2000)
Oncogene
, vol.19
, pp. 2269-2276
-
-
Gire, V.1
Marshall, C.2
Wynford-Thomas, D.3
-
26
-
-
0032502669
-
The epidermal growth factor receptor modulates the interaction of E- Cadherin with the actin cytoskeleton
-
R. B. Hazan & L. Norton: The epidermal growth factor receptor modulates the interaction of E- cadherin with the actin cytoskeleton. J Biol Chem 273, 9078-9084. (1998)
-
(1998)
J Biol Chem
, vol.273
, pp. 9078-9084
-
-
Hazan, R.B.1
Norton, L.2
-
27
-
-
0032586952
-
Stimulation of beta1-integrin function by epidermal growth factor and heregulin-beta has distinct requirements for erbB2 but a similar dependence on phosphoinositide 3-OH kinase
-
M. A. Adelsman, J. B. McCarthy & Y. Shimizu: Stimulation of beta1-integrin function by epidermal growth factor and heregulin-beta has distinct requirements for erbB2 but a similar dependence on phosphoinositide 3-OH kinase. MoL Biol Cell 10, 2861-2878. (1999)
-
(1999)
Mol Biol Cell
, vol.10
, pp. 2861-2878
-
-
Adelsman, M.A.1
McCarthy, J.B.2
Shimizu, Y.3
-
28
-
-
0032549570
-
Overexpression of EGFR and c-erbB2 causes enhanced cell migration in human breast cancer cells and NIH3T3 fibroblasts
-
B. S. Verbeek, S. S. Adriaansen-Slot, T. M. Vroom, T. Beckers & G. Rijksen: Overexpression of EGFR and c-erbB2 causes enhanced cell migration in human breast cancer cells and NIH3T3 fibroblasts. FEBS Lett 425, 145-150. (1998)
-
(1998)
FEBS Lett
, vol.425
, pp. 145-150
-
-
Verbeek, B.S.1
Adriaansen-Slot, S.S.2
Vroom, T.M.3
Beckers, T.4
Rijksen, G.5
-
29
-
-
0029960701
-
EGF receptor signaling enhances in vivo invasiveness of DU-145 human prostate carcinoma cells
-
T. Turner, P. Chen, L. J. Goodly & A. Wells: EGF receptor signaling enhances in vivo invasiveness of DU-145 human prostate carcinoma cells. Clin Exp Metastasis 14, 409-418. (1996)
-
(1996)
Clin Exp Metastasis
, vol.14
, pp. 409-418
-
-
Turner, T.1
Chen, P.2
Goodly, L.J.3
Wells, A.4
-
30
-
-
0031901936
-
In vitro invasion of small-cell lung cancer cell lines correlates with expression of epidermal growth factor receptor
-
L. Damstrup, B. Rude Voldborg, M. Spang-Thomsen, N. Brunner & H. Skovgaard Poulsen: In vitro invasion of small-cell lung cancer cell lines correlates with expression of epidermal growth factor receptor. Br J Cancer 78, 631-640. (1998)
-
(1998)
Br J Cancer
, vol.78
, pp. 631-640
-
-
Damstrup, L.1
Rude Voldborg, B.2
Spang-Thomsen, M.3
Brunner, N.4
Skovgaard Poulsen, H.5
-
31
-
-
0031858958
-
Establishing a link between oncogenes and tumor angiogenesis
-
R. S. Kerbel, A. Viloria-Petit, F. Okada & J. Rak: Establishing a link between oncogenes and tumor angiogenesis. Mol Med 4, 286-295. (1998)
-
(1998)
Mol Med
, vol.4
, pp. 286-295
-
-
Kerbel, R.S.1
Viloria-Petit, A.2
Okada, F.3
Rak, J.4
-
32
-
-
0032418416
-
A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice
-
E. C. Holland, W. P. Hively, R. A. DePinho & H. E. Varmus: A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice. Genes Dev 12, 3675-3685. (1998)
-
(1998)
Genes Dev
, vol.12
, pp. 3675-3685
-
-
Holland, E.C.1
Hively, W.P.2
DePinho, R.A.3
Varmus, H.E.4
-
33
-
-
0034020459
-
Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
-
E. C. Holland, J. Celestino, C. Dai, L. Schaefer, R. E. Sawaya & G. N. Fuller: Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice. Nat Genet 25, 55-57. (2000)
-
(2000)
Nat Genet
, vol.25
, pp. 55-57
-
-
Holland, E.C.1
Celestino, J.2
Dai, C.3
Schaefer, L.4
Sawaya, R.E.5
Fuller, G.N.6
-
34
-
-
0021932240
-
Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin
-
T. A. Libermann, H. R. Nusbaum, N. Razon, R. Kris, I. Lax, H. Soreq, N. Whittle, M. D. Waterfield, A. Ullrich & J. Schlessinger: Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin. Nature 313, 144-147. (1985)
-
(1985)
Nature
, vol.313
, pp. 144-147
-
-
Libermann, T.A.1
Nusbaum, H.R.2
Razon, N.3
Kris, R.4
Lax, I.5
Soreq, H.6
Whittle, N.7
Waterfield, M.D.8
Ullrich, A.9
Schlessinger, J.10
-
35
-
-
0034163550
-
Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas
-
L. Frederick, X. Y. Wang, G. Eley & C. D. James: Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas. Cancer Res 60, 1383-1387. (2000)
-
(2000)
Cancer Res
, vol.60
, pp. 1383-1387
-
-
Frederick, L.1
Wang, X.Y.2
Eley, G.3
James, C.D.4
-
36
-
-
0022372783
-
Amplification and overexpression of the EGF receptor gene in primary human glioblastomas
-
T. A. Libermann, H. R. Nusbaum, N. Razon, R. Kris, I. Lax, H. Soreq, N. Whittle, M. D. Waterfield, A. Ullrich & J. Schlessinger: Amplification and overexpression of the EGF receptor gene in primary human glioblastomas. J Cell Sci Suppl 3, 161-172 (1985)
-
(1985)
J Cell Sci Suppl
, vol.3
, pp. 161-172
-
-
Libermann, T.A.1
Nusbaum, H.R.2
Razon, N.3
Kris, R.4
Lax, I.5
Soreq, H.6
Whittle, N.7
Waterfield, M.D.8
Ullrich, A.9
Schlessinger, J.10
-
37
-
-
0023429079
-
Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification
-
A. J. Wong, S. H. Bigner, D. D. Bigner, K. W. Kinzler, S. R. Hamilton & B. Vogelstein: Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification. Proc Natl Acad Sci U S A 84, 6899-6903. (1987)
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 6899-6903
-
-
Wong, A.J.1
Bigner, S.H.2
Bigner, D.D.3
Kinzler, K.W.4
Hamilton, S.R.5
Vogelstein, B.6
-
38
-
-
0034915394
-
Glioblastoma-related gene mutations and over-expression of functional epidermal growth factor receptors in SKMG-3 glioma cells
-
C. Thomas, G. Ely, C. D. James, R. Jenkins, M. Kastan, A. Jedlicka, P. Burger & R. Wharen: Glioblastoma-related gene mutations and over-expression of functional epidermal growth factor receptors in SKMG-3 glioma cells. Acta Neuropathol (Berl) 101, 605-615. (2001)
-
(2001)
Acta Neuropathol (Berl)
, vol.101
, pp. 605-615
-
-
Thomas, C.1
Ely, G.2
James, C.D.3
Jenkins, R.4
Kastan, M.5
Jedlicka, A.6
Burger, P.7
Wharen, R.8
-
39
-
-
0025686126
-
Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts
-
S. H. Bigner, P. A. Humphrey, A. J. Wong, B. Vogelstein, J. Mark, H. S. Friedman & D. D. Bigner: Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts. Cancer Res 50, 8017-8022. (1990)
-
(1990)
Cancer Res
, vol.50
, pp. 8017-8022
-
-
Bigner, S.H.1
Humphrey, P.A.2
Wong, A.J.3
Vogelstein, B.4
Mark, J.5
Friedman, H.S.6
Bigner, D.D.7
-
40
-
-
0026548240
-
Structural alterations of the epidermal growth factor receptor gene in human gliomas
-
A. J. Wong, J. M. Ruppert, S. H. Bigner, C. H. Grzeschik, P. A. Humphrey, D. S. Bigner & B. Vogelstein: Structural alterations of the epidermal growth factor receptor gene in human gliomas. Proc Natl Acad Sci U S A 89, 2965-2969. (1992)
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 2965-2969
-
-
Wong, A.J.1
Ruppert, J.M.2
Bigner, S.H.3
Grzeschik, C.H.4
Humphrey, P.A.5
Bigner, D.S.6
Vogelstein, B.7
-
41
-
-
0026521394
-
Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- And/or C-terminal tails
-
A. J. Ekstrand, N. Sugawa, C. D. James & V. P. Collins: Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails. Proc Natl Acad Sci U S A 89, 4309-4313. (1992)
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 4309-4313
-
-
Ekstrand, A.J.1
Sugawa, N.2
James, C.D.3
Collins, V.P.4
-
43
-
-
0028955388
-
Epidermal growth factor-related peptides and their receptors in human malignancies
-
D. S. Salomon, R. Brandt, F. Ciardiello & N. Normanno: Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 19, 183-232. (1995)
-
(1995)
Crit Rev Oncol Hematol
, vol.19
, pp. 183-232
-
-
Salomon, D.S.1
Brandt, R.2
Ciardiello, F.3
Normanno, N.4
-
44
-
-
0025790916
-
Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo
-
A. J. Ekstrand, C. D. James, W. K. Cavenee, B. Seliger, R. F. Pettersson & V. P. Collins: Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo. Cancer Res 51, 2164-2172. (1991)
-
(1991)
Cancer Res
, vol.51
, pp. 2164-2172
-
-
Ekstrand, A.J.1
James, C.D.2
Cavenee, W.K.3
Seliger, B.4
Pettersson, R.F.5
Collins, V.P.6
-
45
-
-
0028237507
-
Functional characterization of an EGF receptor with a truncated extracellular domain expressed in glioblastomas with EGFR gene amplification
-
A. J. Ekstrand, N. Longo, M. L. Hamid, J. J. Olson, L. Liu, V. P. Collins & C. D. James: Functional characterization of an EGF receptor with a truncated extracellular domain expressed in glioblastomas with EGFR gene amplification. Oncogens 9, 2313-2320. (1994)
-
(1994)
Oncogens
, vol.9
, pp. 2313-2320
-
-
Ekstrand, A.J.1
Longo, N.2
Hamid, M.L.3
Olson, J.J.4
Liu, L.5
Collins, V.P.6
James, C.D.7
-
46
-
-
0028146767
-
A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity
-
R. Nishikawa, X. D. Ji, R. C. Harmon, C. S. Lazar, G. N. Gill, W. K. Cavenee & H. J. Huang: A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity. Proc Natl Acad Sci U S A 91, 7727-7731. (1994)
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 7727-7731
-
-
Nishikawa, R.1
Ji, X.D.2
Harmon, R.C.3
Lazar, C.S.4
Gill, G.N.5
Cavenee, W.K.6
Huang, H.J.7
-
47
-
-
0029666423
-
Transformational and altered signal transduction by a naturally occurring mutant EGF receptor
-
D. K. Moscatello, R. B. Montgomery, P. Sundareshan, H. McDanel, M. Y. Wong & A. J. Wong: Transformational and altered signal transduction by a naturally occurring mutant EGF receptor. Oncogene 13, 85-96. (1996)
-
(1996)
Oncogene
, vol.13
, pp. 85-96
-
-
Moscatello, D.K.1
Montgomery, R.B.2
Sundareshan, P.3
McDanel, H.4
Wong, M.Y.5
Wong, A.J.6
-
48
-
-
14444288522
-
The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling
-
H. S. Huang, M. Nagane, C. K. Klingbeil, H. Lin, R. Nishikawa, X. D. Ji, C. M. Huang, G. N. Gill, H. S. Wiley & W. K. Cavenee: The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling. J Biol Chem 272, 2927-2935. (1997)
-
(1997)
J Biol Chem
, vol.272
, pp. 2927-2935
-
-
Huang, H.S.1
Nagane, M.2
Klingbeil, C.K.3
Lin, H.4
Nishikawa, R.5
Ji, X.D.6
Huang, C.M.7
Gill, G.N.8
Wiley, H.S.9
Cavenee, W.K.10
-
49
-
-
0030787340
-
Receptor dimerization is not a factor in the signalling activity of a transforming variant epidermal growth factor receptor (EGFRvIII)
-
C. T. Chu, K. D. Everiss, C. J. Wikstrand, S. K. Batra, H. J. Kung & D. D. Bigner: Receptor dimerization is not a factor in the signalling activity of a transforming variant epidermal growth factor receptor (EGFRvIII). Biochem J 324, 855-861. (1997)
-
(1997)
Biochem J
, vol.324
, pp. 855-861
-
-
Chu, C.T.1
Everiss, K.D.2
Wikstrand, C.J.3
Batra, S.K.4
Kung, H.J.5
Bigner, D.D.6
-
50
-
-
0029815093
-
Enhanced tumorigenic behavior of glioblastoma cells expressing a truncated epidermal growth factor receptor is mediated through the Ras- Shc-Grb2 pathway
-
S. A. Prigent, M. Nagane, H. Lin, I. Huvar, G. R. Boss, J. R. Feramisco, W. K. Cavenee & H. S. Huang: Enhanced tumorigenic behavior of glioblastoma cells expressing a truncated epidermal growth factor receptor is mediated through the Ras- Shc-Grb2 pathway. J Biol Chem 271, 25639-25645. (1996)
-
(1996)
J Biol Chem
, vol.271
, pp. 25639-25645
-
-
Prigent, S.A.1
Nagane, M.2
Lin, H.3
Huvar, I.4
Boss, G.R.5
Feramisco, J.R.6
Cavenee, W.K.7
Huang, H.S.8
-
51
-
-
0031961980
-
Constitutive activation of phosphatidylinositol 3-kinase by a naturally occurring mutant epidermal growth factor receptor
-
D. K. Moscatello, M. Holgado-Madruga, D. R. Emlet, R. B. Montgomery & A. J. Wong: Constitutive activation of phosphatidylinositol 3-kinase by a naturally occurring mutant epidermal growth factor receptor. J Biol Chem 273, 200-206. (1998)
-
(1998)
J Biol Chem
, vol.273
, pp. 200-206
-
-
Moscatello, D.K.1
Holgado-Madruga, M.2
Emlet, D.R.3
Montgomery, R.B.4
Wong, A.J.5
-
52
-
-
0028863853
-
Epidermal growth factor ligand-independent, unregulated, cell- Transforming potential of a naturally occurring human mutant EGFRvIII gene
-
S. K. Batra, S. Castelino-Prabhu, C. J. Wikstrand, X. Zhu, P. A. Humphrey, H. S. Friedman & D. D. Bigner: Epidermal growth factor ligand-independent, unregulated, cell- transforming potential of a naturally occurring human mutant EGFRvIII gene. Cell Growth Differ 6, 1251-1259. (1995)
-
(1995)
Cell Growth Differ
, vol.6
, pp. 1251-1259
-
-
Batra, S.K.1
Castelino-Prabhu, S.2
Wikstrand, C.J.3
Zhu, X.4
Humphrey, P.A.5
Friedman, H.S.6
Bigner, D.D.7
-
53
-
-
0032246703
-
Function of aberrant EGFR in malignant gliomas
-
N. Sugawa, K. Yamamoto, S. Ueda, N. Morita, M. Kita, H. Nishino, S. Fushiki & T. Okabe: Function of aberrant EGFR in malignant gliomas. Brain Tumor Pathol 15, 53-57 (1998)
-
(1998)
Brain Tumor Pathol
, vol.15
, pp. 53-57
-
-
Sugawa, N.1
Yamamoto, K.2
Ueda, S.3
Morita, N.4
Kita, M.5
Nishino, H.6
Fushiki, S.7
Okabe, T.8
-
54
-
-
0030054132
-
Proliferation and motility responses of primary and recurrent gliomas related to changes in epidermal growth factor receptor expression
-
M. E. Berens, M. D. Rief, J. R. Shapiro, D. Haskett, A. Giese, A. Joy & S. W. Coons: Proliferation and motility responses of primary and recurrent gliomas related to changes in epidermal growth factor receptor expression. J Neurooncol 27, 11-22. (1996)
-
(1996)
J Neurooncol
, vol.27
, pp. 11-22
-
-
Berens, M.E.1
Rief, M.D.2
Shapiro, J.R.3
Haskett, D.4
Giese, A.5
Joy, A.6
Coons, S.W.7
-
55
-
-
0032510679
-
Drug resistance of human glioblastoma cells conferred by a tumor- Specific mutant epidermal growth factor receptor through modulation of Bel-XL and caspase-3-like proteases
-
M. Nagane, A. Levitzki, A. Gazit, W. K. Cavenee & H. J. Huang: Drug resistance of human glioblastoma cells conferred by a tumor- specific mutant epidermal growth factor receptor through modulation of Bel-XL and caspase-3-like proteases. Proc Natl Acad Sci U S A 95, 5724-5729. (1998)
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 5724-5729
-
-
Nagane, M.1
Levitzki, A.2
Gazit, A.3
Cavenee, W.K.4
Huang, H.J.5
-
56
-
-
0029961912
-
A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis
-
M. Nagane, F. Coufal, H. Lin, O. Bogler, W. K. Cavenee & H. J. Huang: A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis. Cancer Res 56, 5079-5086. (1996)
-
(1996)
Cancer Res
, vol.56
, pp. 5079-5086
-
-
Nagane, M.1
Coufal, F.2
Lin, H.3
Bogler, O.4
Cavenee, W.K.5
Huang, H.J.6
-
57
-
-
0030772250
-
The autocrine loop of TGF-alpha/EGFR and brain tumors
-
P. Tang, P. A. Steck & W. K. Yung: The autocrine loop of TGF-alpha/EGFR and brain tumors. J Neurooncol 35, 303-314. (1997)
-
(1997)
J Neurooncol
, vol.35
, pp. 303-314
-
-
Tang, P.1
Steck, P.A.2
Yung, W.K.3
-
58
-
-
0020408487
-
Effect of epidermal growth factor on membrane motility and cell locomotion in cultures of human clonal glioma cells
-
B. Westermark, A. Magnusson & C. H. Heldin: Effect of epidermal growth factor on membrane motility and cell locomotion in cultures of human clonal glioma cells. J Neurosci Res 8, 491-507 (1982)
-
(1982)
J Neurosci Res
, vol.8
, pp. 491-507
-
-
Westermark, B.1
Magnusson, A.2
Heldin, C.H.3
-
59
-
-
0025147270
-
Effect of epidermal growth factor on glioma cell growth, migration, and invasion in vitro
-
M. Lund-Johansen, R. Bjerkvig, P. A. Humphrey, S. H. Bigner, D. D. Bigner & O. D. Laerum: Effect of epidermal growth factor on glioma cell growth, migration, and invasion in vitro. Cancer Res 50, 6039-6044. (1990)
-
(1990)
Cancer Res
, vol.50
, pp. 6039-6044
-
-
Lund-Johansen, M.1
Bjerkvig, R.2
Humphrey, P.A.3
Bigner, S.H.4
Bigner, D.D.5
Laerum, O.D.6
-
60
-
-
0026715782
-
Effects of growth factors on a human glioma cell line during invasion into rat brain aggregates in culture
-
M. Lund-Johansen, K. Forsberg, R. Bjerkvig & O. D. Laerum: Effects of growth factors on a human glioma cell line during invasion into rat brain aggregates in culture. Acta Neuropathol 84, 190-197 (1992)
-
(1992)
Acta Neuropathol
, vol.84
, pp. 190-197
-
-
Lund-Johansen, M.1
Forsberg, K.2
Bjerkvig, R.3
Laerum, O.D.4
-
61
-
-
0028998155
-
Modification of human glioma locomotion in vitro by cytokines EGF, bFGF, PDGFbb, NGF, and TNF alpha
-
M. R. Chicoine, C. L. Madsen & D. L. Silbergeld: Modification of human glioma locomotion in vitro by cytokines EGF, bFGF, PDGFbb, NGF, and TNF alpha. Neurosurgery 36, 1165-1170; discussion 1170-1161. (1995)
-
(1995)
Neurosurgery
, vol.36
, pp. 1165-1170
-
-
Chicoine, M.R.1
Madsen, C.L.2
Silbergeld, D.L.3
-
62
-
-
0027530832
-
Effects of EGF, bFGF, NGF and PDGF(bb) on cell proliferative, migratory and invasive capacities of human brain-tumour biopsies in vitro
-
O. Engebraaten, R. Bjerkvig, P. H. Pedersen & O. D. Laerum: Effects of EGF, bFGF, NGF and PDGF(bb) on cell proliferative, migratory and invasive capacities of human brain-tumour biopsies in vitro. Int J Cancer 53, 209-214. (1993)
-
(1993)
Int J Cancer
, vol.53
, pp. 209-214
-
-
Engebraaten, O.1
Bjerkvig, R.2
Pedersen, P.H.3
Laerum, O.D.4
-
63
-
-
0028351179
-
Heterogeneous response to the growth factors (EGF, PDGF (bb), TGF-alpha, bFGF, IL-2) on glioma spheroid growth, migration and invasion
-
P. H. Pedersen, G. O. Ness, O. Engebraaten, R. Bjerkvig, J. R. Lillehaug & O. D. Laerum: Heterogeneous response to the growth factors (EGF, PDGF (bb), TGF-alpha, bFGF, IL-2) on glioma spheroid growth, migration and invasion. Int J Cancer 56, 255-261. (1994)
-
(1994)
Int J Cancer
, vol.56
, pp. 255-261
-
-
Pedersen, P.H.1
Ness, G.O.2
Engebraaten, O.3
Bjerkvig, R.4
Lillehaug, J.R.5
Laerum, O.D.6
-
64
-
-
0034467330
-
Growth factors in glioma angiogenesis: FGFs, PDGF, EGF, and TGFs
-
I. F. Dunn, O. Heese & P. M. Black: Growth factors in glioma angiogenesis: FGFs, PDGF, EGF, and TGFs. J Neurooncol 50, 121-137. (2000)
-
(2000)
J Neurooncol
, vol.50
, pp. 121-137
-
-
Dunn, I.F.1
Heese, O.2
Black, P.M.3
-
65
-
-
0027412319
-
Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: A model of glioblastoma multiforme pathophysiology
-
C. K. Goldman, J. Kim, W. L. Wong, V. King, T. Brock & G. Y. Gillespie: Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: a model of glioblastoma multiforme pathophysiology. Mol Biol Cell 4, 121-133. (1993)
-
(1993)
Mol Biol Cell
, vol.4
, pp. 121-133
-
-
Goldman, C.K.1
Kim, J.2
Wong, W.L.3
King, V.4
Brock, T.5
Gillespie, G.Y.6
-
66
-
-
0034667464
-
Epidermal growth factor receptor transcriptionally up-regulates vascular endothelial growth factor expression in human glioblastoma cells via a pathway involving phosphatidylinositol 3′-kinase and distinct from that induced by hypoxia
-
A. Maity, N. Pore, J. Lee, D. Solomon & D. M. O'Rourke: Epidermal growth factor receptor transcriptionally up-regulates vascular endothelial growth factor expression in human glioblastoma cells via a pathway involving phosphatidylinositol 3′-kinase and distinct from that induced by hypoxia. Cancer Res 60, 5879-5886. (2000)
-
(2000)
Cancer Res
, vol.60
, pp. 5879-5886
-
-
Maity, A.1
Pore, N.2
Lee, J.3
Solomon, D.4
O'Rourke, D.M.5
-
67
-
-
0023747564
-
Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines
-
M. Nister, T. A. Libermann, C. Betsholtz, M. Pettersson, L. Claesson-Welsh, C. H. Heldin, J. Schlessinger & B. Westermark: Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines. Cancer Res 48, 3910-3918. (1988)
-
(1988)
Cancer Res
, vol.48
, pp. 3910-3918
-
-
Nister, M.1
Libermann, T.A.2
Betsholtz, C.3
Pettersson, M.4
Claesson-Welsh, L.5
Heldin, C.H.6
Schlessinger, J.7
Westermark, B.8
-
68
-
-
0025604180
-
Expression of transforming growth factor alpha in human gliomas
-
U. Schlegel, P. L. Moots, M. K. Rosenblum, H. T. Thaler & H. M. Furneaux: Expression of transforming growth factor alpha in human gliomas. Oncogene 5, 1839-1842. (1990)
-
(1990)
Oncogene
, vol.5
, pp. 1839-1842
-
-
Schlegel, U.1
Moots, P.L.2
Rosenblum, M.K.3
Thaler, H.T.4
Furneaux, H.M.5
-
69
-
-
0030938231
-
Prenatal ontogeny of the epidermal growth factor receptor and its ligand, transforming growth factor alpha, in the rat brain
-
H. I. Kornblum, R. J. Hussain, J. M. Bronstein, C. M. Gall, D. C. Lee & K. B. Seroogy: Prenatal ontogeny of the epidermal growth factor receptor and its ligand, transforming growth factor alpha, in the rat brain. J Comp Neurol 380, 243-261. (1997)
-
(1997)
J Comp Neurol
, vol.380
, pp. 243-261
-
-
Kornblum, H.I.1
Hussain, R.J.2
Bronstein, J.M.3
Gall, C.M.4
Lee, D.C.5
Seroogy, K.B.6
-
70
-
-
0030869136
-
Response diversity and the timing of progenitor cell maturation are regulated by developmental changes in EGFR expression in the cortex
-
R. C. Burrows, D. Wancio, P. Levitt & L. Lillien: Response diversity and the timing of progenitor cell maturation are regulated by developmental changes in EGFR expression in the cortex. Neuron 19, 251-267. (1997)
-
(1997)
Neuron
, vol.19
, pp. 251-267
-
-
Burrows, R.C.1
Wancio, D.2
Levitt, P.3
Lillien, L.4
-
71
-
-
0028814611
-
Proliferative zones of postnatal rat brain express epidermal growth factor receptor mRNA
-
K. B. Seroogy, C. M. Gall, D. C. Lee & H. I. Kornblum: Proliferative zones of postnatal rat brain express epidermal growth factor receptor mRNA. Brain Res 670, 157-164. (1995)
-
(1995)
Brain Res
, vol.670
, pp. 157-164
-
-
Seroogy, K.B.1
Gall, C.M.2
Lee, D.C.3
Kornblum, H.I.4
-
72
-
-
0029798628
-
Expression of EGFR-, p75NGFR-, and PSTAIR (cdc2)-like immunoreactivity by proliferating cells in the adult rat hippocampal formation and forebrain
-
H. J. Okano, D. W. Pfaff & R. B. Gibbs: Expression of EGFR-, p75NGFR-, and PSTAIR (cdc2)-like immunoreactivity by proliferating cells in the adult rat hippocampal formation and forebrain. Dev Neurosci 18, 199-209 (1996)
-
(1996)
Dev Neurosci
, vol.18
, pp. 199-209
-
-
Okano, H.J.1
Pfaff, D.W.2
Gibbs, R.B.3
-
73
-
-
0028299339
-
Glial growth factor restricts mammalian neural crest stem cells to a glial fate
-
N. M. Shah, M. A. Marchionni, I. Isaacs, P. Stroobant & D. J. Anderson: Glial growth factor restricts mammalian neural crest stem cells to a glial fate. Cell 77, 349-360. (1994)
-
(1994)
Cell
, vol.77
, pp. 349-360
-
-
Shah, N.M.1
Marchionni, M.A.2
Isaacs, I.3
Stroobant, P.4
Anderson, D.J.5
-
74
-
-
0025239422
-
Riding the glial monorail: A common mechanism for glial-guided neuronal migration in different regions of the developing mammalian brain
-
M. E. Hatten: Riding the glial monorail: a common mechanism for glial-guided neuronal migration in different regions of the developing mammalian brain. Trends Neurosci 13, 179-184. (1990)
-
(1990)
Trends Neurosci
, vol.13
, pp. 179-184
-
-
Hatten, M.E.1
-
75
-
-
0035960071
-
Radial glial cells. Are they really glia?
-
J. G. Parnavelas & B. Nadarajah: Radial glial cells. are they really glia? Neuron 31, 881-884. (2001)
-
(2001)
Neuron
, vol.31
, pp. 881-884
-
-
Parnavelas, J.G.1
Nadarajah, B.2
-
76
-
-
0027983925
-
Genesis of olfactory receptor neurons in vitro: Regulation of progenitor cell divisions by fibroblast growth factors
-
M. K. DeHamer, J. L. Guevara, K. Hannon, B. B. Olwin & A. L. Calof: Genesis of olfactory receptor neurons in vitro: regulation of progenitor cell divisions by fibroblast growth factors. Neuron 13, 1083-1097. (1994)
-
(1994)
Neuron
, vol.13
, pp. 1083-1097
-
-
Dehamer, M.K.1
Guevara, J.L.2
Hannon, K.3
Olwin, B.B.4
Calof, A.L.5
-
77
-
-
0028902623
-
Intrinsic and extrinsic factors regulating vertebrate neurogenesis
-
A. L. Calof: Intrinsic and extrinsic factors regulating vertebrate neurogenesis. Curr Opin Neurobiol 5, 19-27. (1995)
-
(1995)
Curr Opin Neurobiol
, vol.5
, pp. 19-27
-
-
Calof, A.L.1
-
78
-
-
0024282573
-
Platelet-derived growth factor promotes division and motility and inhibits premature differentiation of the oligodendrocyte/type-2 astrocyte progenitor cell
-
M. Noble, K. Murray, P. Stroobant, M. D. Waterfield & P. Riddle: Platelet-derived growth factor promotes division and motility and inhibits premature differentiation of the oligodendrocyte/type-2 astrocyte progenitor cell. Nature 333, 560-562. (1988)
-
(1988)
Nature
, vol.333
, pp. 560-562
-
-
Noble, M.1
Murray, K.2
Stroobant, P.3
Waterfield, M.D.4
Riddle, P.5
-
79
-
-
0024282594
-
Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture
-
M. C. Raff, L. E. Lillien, W. D. Richardson, J. F. Burne & M. D. Noble: Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture. Nature 333, 562-565. (1988)
-
(1988)
Nature
, vol.333
, pp. 562-565
-
-
Raff, M.C.1
Lillien, L.E.2
Richardson, W.D.3
Burne, J.F.4
Noble, M.D.5
-
80
-
-
0022468128
-
Clonal analysis of oligodendrocyte development in culture: Evidence for a developmental clock that counts cell divisions
-
S. Temple & M. C. Raff: Clonal analysis of oligodendrocyte development in culture: evidence for a developmental clock that counts cell divisions. Cell 44, 773-779. (1986)
-
(1986)
Cell
, vol.44
, pp. 773-779
-
-
Temple, S.1
Raff, M.C.2
-
81
-
-
0025200507
-
FGF modulates the PDGF-driven pathway of oligodendrocyte development
-
R. D. McKinnon, T. Matsui, M. Dubois-Dalcq & S. A. Aaronson: FGF modulates the PDGF-driven pathway of oligodendrocyte development. Neuron 5, 603-614. (1990)
-
(1990)
Neuron
, vol.5
, pp. 603-614
-
-
McKinnon, R.D.1
Matsui, T.2
Dubois-Dalcq, M.3
Aaronson, S.A.4
-
82
-
-
0025142474
-
Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells
-
O. Bogler, D. Wren, S. C. Barnett, H. Land & M. Noble: Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells. Proc Natl Acad Sci U S A 87, 6368-6372. (1990)
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 6368-6372
-
-
Bogler, O.1
Wren, D.2
Barnett, S.C.3
Land, H.4
Noble, M.5
-
83
-
-
0027491410
-
bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells
-
A. L. Vescovi, B. A. Reynolds, D. D. Fraser & S. Weiss: bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells. Neuron 11, 951-966. (1993)
-
(1993)
Neuron
, vol.11
, pp. 951-966
-
-
Vescovi, A.L.1
Reynolds, B.A.2
Fraser, D.D.3
Weiss, S.4
-
84
-
-
0031029569
-
FGF2 concentration regulates the generation of neurons and glia from multipotent cortical stem cells
-
X. Qian, A. A. Davis, S. K. Goderie & S. Temple: FGF2 concentration regulates the generation of neurons and glia from multipotent cortical stem cells. Neuron 18, 81-93. (1997)
-
(1997)
Neuron
, vol.18
, pp. 81-93
-
-
Qian, X.1
Davis, A.A.2
Goderie, S.K.3
Temple, S.4
-
85
-
-
0028980528
-
Transforming growth factor-beta-3 is mitogenic for rat retinal progenitor cells in vitro
-
R. M. Anchan & T. A. Reh: Transforming growth factor-beta-3 is mitogenic for rat retinal progenitor cells in vitro. J Neurobiol 28, 133-145. (1995)
-
(1995)
J Neurobiol
, vol.28
, pp. 133-145
-
-
Anchan, R.M.1
Reh, T.A.2
-
86
-
-
0027537295
-
Peptide growth factor control of olfactory neurogenesis and neuron survival in vitro: Roles of EGF and TGF-beta s
-
N. K. Mahanthappa & G. A. Schwarting: Peptide growth factor control of olfactory neurogenesis and neuron survival in vitro: roles of EGF and TGF-beta s. Neuron 10, 293-305. (1993)
-
(1993)
Neuron
, vol.10
, pp. 293-305
-
-
Mahanthappa, N.K.1
Schwarting, G.A.2
-
87
-
-
0033970281
-
Developmental changes in progenitor cell responsiveness to bone morphogenetic proteins differentially modulate progressive CNS lineage fate
-
M. F. Mehler, P. C. Mabie, G. Zhu, S. Gokhan & J. A. Kessler: Developmental changes in progenitor cell responsiveness to bone morphogenetic proteins differentially modulate progressive CNS lineage fate. Dev Neurosci 22, 74-85 (2000)
-
(2000)
Dev Neurosci
, vol.22
, pp. 74-85
-
-
Mehler, M.F.1
Mabie, P.C.2
Zhu, G.3
Gokhan, S.4
Kessler, J.A.5
-
88
-
-
0030953874
-
Insulin-like growth factor I (IGF-I) is a critical trophic factor for developing cerebellar granule cells
-
X. Lin & R. F. Bulleit: Insulin-like growth factor I (IGF-I) is a critical trophic factor for developing cerebellar granule cells. Brain Res Dev Brain Res 99, 234-242. (1997)
-
(1997)
Brain Res Dev Brain Res
, vol.99
, pp. 234-242
-
-
Lin, X.1
Bulleit, R.F.2
-
89
-
-
0031767299
-
A transient role for ciliary neurotrophic factor in chick photoreceptor development
-
S. Fuhrmann, S. Heller, H. Rohrer & H. D. Hofmann: A transient role for ciliary neurotrophic factor in chick photoreceptor development. J Neurobiol 37, 672-683. (1998)
-
(1998)
J Neurobiol
, vol.37
, pp. 672-683
-
-
Fuhrmann, S.1
Heller, S.2
Rohrer, H.3
Hofmann, H.D.4
-
90
-
-
0032539913
-
Neural precursor differentiation into astrocytes requires signaling through the leukemia inhibitory factor receptor
-
S. A. Koblar, A. M. Turnley, B. J. Classon, K. L. Reid, C. B. Ware, S. S. Cheema, M. Murphy & P. F. Bartlett: Neural precursor differentiation into astrocytes requires signaling through the leukemia inhibitory factor receptor. Proc Natl Acad Sci U S A 95, 3178-3181. (1998)
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 3178-3181
-
-
Koblar, S.A.1
Turnley, A.M.2
Classon, B.J.3
Reid, K.L.4
Ware, C.B.5
Cheema, S.S.6
Murphy, M.7
Bartlett, P.F.8
-
91
-
-
0034104525
-
Tyrosine kinase inhibitors targeted to the epidermal growth factor receptor subfamily: Role as anticancer agents
-
S. B. Noonberg & C. C. Benz: Tyrosine kinase inhibitors targeted to the epidermal growth factor receptor subfamily: role as anticancer agents. Drugs 59, 753-767. (2000)
-
(2000)
Drugs
, vol.59
, pp. 753-767
-
-
Noonberg, S.B.1
Benz, C.C.2
-
92
-
-
0034988184
-
The epidermal growth factor receptor as a target for cancer therapy
-
J. Mendelsohn: The epidermal growth factor receptor as a target for cancer therapy. Endocr Relat Cancer 8, 3-9. (2001)
-
(2001)
Endocr Relat Cancer
, vol.8
, pp. 3-9
-
-
Mendelsohn, J.1
-
93
-
-
0010233988
-
Growth stimulation of A431 cells by epidermal growth factor: Identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody
-
T. Kawamoto, J. D. Sato, A. Le, J. Polikoff, G. H. Sato & J. Mendelsohn: Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody. Proc Natl Acad Sci U S A 80, 1337-1341. (1983)
-
(1983)
Proc Natl Acad Sci U S A
, vol.80
, pp. 1337-1341
-
-
Kawamoto, T.1
Sato, J.D.2
Le, A.3
Polikoff, J.4
Sato, G.H.5
Mendelsohn, J.6
-
94
-
-
0021254542
-
Monoclonal anti-epidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factor binding and antagonists of epidermal growth factor-stimulated tyrosine protein kinase activity
-
G. N. Gill, T. Kawamoto, C. Cochet, A. Le, J. D. Sato, H. Masui, C. McLeod & J. Mendelsohn: Monoclonal anti-epidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factor binding and antagonists of epidermal growth factor-stimulated tyrosine protein kinase activity. J Biol Chem 259, 7755-7760. (1984)
-
(1984)
J Biol Chem
, vol.259
, pp. 7755-7760
-
-
Gill, G.N.1
Kawamoto, T.2
Cochet, C.3
Le, A.4
Sato, J.D.5
Masui, H.6
McLeod, C.7
Mendelsohn, J.8
-
95
-
-
0032972944
-
Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice
-
P. Perrotte, T. Matsumoto, K. Inoue, H. Kuniyasu, B. Y. Eve, D. J. Hicklin, R. Radinsky & C. P. Dinney: Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice. Clin Cancer Res 5, 257-265. (1999)
-
(1999)
Clin Cancer Res
, vol.5
, pp. 257-265
-
-
Perrotte, P.1
Matsumoto, T.2
Inoue, K.3
Kuniyasu, H.4
Eve, B.Y.5
Hicklin, D.J.6
Radinsky, R.7
Dinney, C.P.8
-
96
-
-
0001223491
-
Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: Angiogenic implications for signal transduction therapy of solid tumors
-
A. M. Petit, J. Rak, M. C. Hung, P. Rockwell, N. Goldstein, B. Fendly & R. S. Kerbel: Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy of solid tumors. Am J Pathol 151, 1523-1530. (1997)
-
(1997)
Am J Pathol
, vol.151
, pp. 1523-1530
-
-
Petit, A.M.1
Rak, J.2
Hung, M.C.3
Rockwell, P.4
Goldstein, N.5
Fendly, B.6
Kerbel, R.S.7
-
97
-
-
12944309909
-
Unarmed, tumor-specific monoclonal antibody effectively treats brain tumors
-
J. H. Sampson, L. E. Crotty, S. Lee, G. E. Archer, D. M. Ashley, C. J. Wikstrand, L. P. Hale, C. Small, G. Dranoff, A. H. Friedman, H. S. Friedman & D. D. Bigner: Unarmed, tumor-specific monoclonal antibody effectively treats brain tumors. Proc Natl Acad Sci U S A 97, 7503-7508. (2000)
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 7503-7508
-
-
Sampson, J.H.1
Crotty, L.E.2
Lee, S.3
Archer, G.E.4
Ashley, D.M.5
Wikstrand, C.J.6
Hale, L.P.7
Small, C.8
Dranoff, G.9
Friedman, A.H.10
Friedman, H.S.11
Bigner, D.D.12
-
98
-
-
0035878746
-
Growth suppression of intracranial xenografted glioblastomas overexpressing mutant epidermal growth factor receptors by systemic administration of monoclonal antibody (mAb) 806, a novel monoclonal antibody directed to the receptor
-
K. Mishima, T. G. Johns, R. B. Luwor, A. M. Scott, E. Stocken, A. A. Jungbluth, X. D. Ji, P. Suvarna, J. R. Voland, L. J. Old, H. J. Huang & W. K. Cavenee: Growth suppression of intracranial xenografted glioblastomas overexpressing mutant epidermal growth factor receptors by systemic administration of monoclonal antibody (mAb) 806, a novel monoclonal antibody directed to the receptor. Cancer Res 61, 5349-5354. (2001)
-
(2001)
Cancer Res
, vol.61
, pp. 5349-5354
-
-
Mishima, K.1
Johns, T.G.2
Luwor, R.B.3
Scott, A.M.4
Stocken, E.5
Jungbluth, A.A.6
Ji, X.D.7
Suvarna, P.8
Voland, J.R.9
Old, L.J.10
Huang, H.J.11
Cavenee, W.K.12
-
99
-
-
0035878671
-
Monoclonal antibody 806 inhibits the growth of tumor xenografts expressing either the de2-7 or amplified epidermal growth factor receptor (EGFR) but not wild-type EGFR
-
R. B. Luwor, T. G. Johns, C. Murone, H. J. Huang, W. K. Cavenee, G. Ritter, L. J. Old, A. W. Burgess & A. M. Scott: Monoclonal antibody 806 inhibits the growth of tumor xenografts expressing either the de2-7 or amplified epidermal growth factor receptor (EGFR) but not wild-type EGFR. Cancer Res 61, 5355-5361. (2001)
-
(2001)
Cancer Res
, vol.61
, pp. 5355-5361
-
-
Luwor, R.B.1
Johns, T.G.2
Murone, C.3
Huang, H.J.4
Cavenee, W.K.5
Ritter, G.6
Old, L.J.7
Burgess, A.W.8
Scott, A.M.9
-
100
-
-
0028826233
-
In vitro and in vivo stability and anti-tumour efficacy of an anti- EGFR/anti-CD3 F(ab′)2 bispecific monoclonal antibody
-
D. R. Negri, E. Tosi, O. Valota, S. Ferrini, A. Cambiaggi, S. Sforzini, A. Silvani, P. A. Ruffini, M. I. Colnaghi & S. Canevari: In vitro and in vivo stability and anti-tumour efficacy of an anti- EGFR/anti-CD3 F(ab′)2 bispecific monoclonal antibody. Br J Cancer 72, 928-933. (1995)
-
(1995)
Br J Cancer
, vol.72
, pp. 928-933
-
-
Negri, D.R.1
Tosi, E.2
Valota, O.3
Ferrini, S.4
Cambiaggi, A.5
Sforzini, S.6
Silvani, A.7
Ruffini, P.A.8
Colnaghi, M.I.9
Canevari, S.10
-
101
-
-
0034087465
-
Recombinant antibody toxins specific for ErbB2 and EGF receptor inhibit the in vitro growth of human head and neck cancer cells and cause rapid tumor regression in vivo
-
M. Azemar, M. Schmidt, F. Arlt, P. Kennel, B. Brandt, A. Papadimitriou, B. Groner & W. Wels: Recombinant antibody toxins specific for ErbB2 and EGF receptor inhibit the in vitro growth of human head and neck cancer cells and cause rapid tumor regression in vivo. Int J Cancer 86, 269-275. (2000)
-
(2000)
Int J Cancer
, vol.86
, pp. 269-275
-
-
Azemar, M.1
Schmidt, M.2
Arlt, F.3
Kennel, P.4
Brandt, B.5
Papadimitriou, A.6
Groner, B.7
Wels, W.8
-
102
-
-
0033522201
-
Suppression of metastasis formation by a recombinant single chain antibody-toxin targeted to full-length and oncogenic variant EGF receptors
-
M. Schmidt, M. Maurer-Gebhard, B. Groner, G. Kohler, G. Brochmann-Santos & W. Wels: Suppression of metastasis formation by a recombinant single chain antibody-toxin targeted to full-length and oncogenic variant EGF receptors. Oncogene 18, 1711-1721. (1999)
-
(1999)
Oncogene
, vol.18
, pp. 1711-1721
-
-
Schmidt, M.1
Maurer-Gebhard, M.2
Groner, B.3
Kohler, G.4
Brochmann-Santos, G.5
Wels, W.6
-
103
-
-
0034068319
-
Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor- Selective tyrosine kinase inhibitor
-
F. Ciardiello, R. Caputo, R. Bianco, V. Damiano, G. Pomatico, S. De Placido, A. R. Bianco & G. Tortora: Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor- selective tyrosine kinase inhibitor. Clin Cancer Res 6, 2053-2063. (2000)
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2053-2063
-
-
Ciardiello, F.1
Caputo, R.2
Bianco, R.3
Damiano, V.4
Pomatico, G.5
De Placido, S.6
Bianco, A.R.7
Tortora, G.8
-
104
-
-
0032695910
-
Inhibition of epidermal growth factor receptor-associated tyrosine phosphorylation in human carcinomas with CP-358,774: Dynamics of receptor inhibition in situ and antitumor effects in athymic mice
-
V. A. Pollack, D. M. Savage, D. A. Baker, K. E. Tsaparikos, D. E. Sloan, J. D. Moyer, E. G. Barbacci, L. R. Pustilnik, T. A. Smolarek, J. A. Davis, M. P. Vaidya, L. D. Arnold, J. L. Doty, K. K. Iwata & M. J. Morin: Inhibition of epidermal growth factor receptor-associated tyrosine phosphorylation in human carcinomas with CP-358,774: dynamics of receptor inhibition in situ and antitumor effects in athymic mice. J Pharmacol Exp Ther 291, 739-748. (1999)
-
(1999)
J Pharmacol Exp Ther
, vol.291
, pp. 739-748
-
-
Pollack, V.A.1
Savage, D.M.2
Baker, D.A.3
Tsaparikos, K.E.4
Sloan, D.E.5
Moyer, J.D.6
Barbacci, E.G.7
Pustilnik, L.R.8
Smolarek, T.A.9
Davis, J.A.10
Vaidya, M.P.11
Arnold, L.D.12
Doty, J.L.13
Iwata, K.K.14
Morin, M.J.15
-
105
-
-
0034611617
-
Tyrosine Kinase Inhibitors. 17. Irreversible Inhibitors of the Epidermal Growth Factor Receptor: 4-(Phenylamino)quinazoline- And 4- (Phenylamino)pyrido
-
J. B. Smaill, G. W. Rewcastle, J. A. Loo, K. D. Greis, O. H. Chan, E. L. Reyner, E. Lipka, H. D. Showalter, P. W. Vincent, W. L. Elliott & W. A. Denny: Tyrosine Kinase Inhibitors. 17. Irreversible Inhibitors of the Epidermal Growth Factor Receptor: 4-(Phenylamino)quinazoline- and 4- (Phenylamino)pyrido. J Med Chem 43, 1380-1397. (2000)
-
(2000)
J Med Chem
, vol.43
, pp. 1380-1397
-
-
Smaill, J.B.1
Rewcastle, G.W.2
Loo, J.A.3
Greis, K.D.4
Chan, O.H.5
Reyner, E.L.6
Lipka, E.7
Showalter, H.D.8
Vincent, P.W.9
Elliott, W.L.10
Denny, W.A.11
-
106
-
-
0034212763
-
Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma
-
C. J. Bruns, C. C. Solorzano, M. T. Harbison, S. Ozawa, R. Tsan, D. Fan, J. Abbruzzese, P. Traxler, E. Buchdunger, R. Radinsky & I. J. Fidler: Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma. Cancer Res 60, 2926-2935. (2000)
-
(2000)
Cancer Res
, vol.60
, pp. 2926-2935
-
-
Bruns, C.J.1
Solorzano, C.C.2
Harbison, M.T.3
Ozawa, S.4
Tsan, R.5
Fan, D.6
Abbruzzese, J.7
Traxler, P.8
Buchdunger, E.9
Radinsky, R.10
Fidler, I.J.11
-
107
-
-
0036490442
-
Smart drugs: Tyrosine kinase inhibitors in cancer therapy
-
L. K. Shawver, D. Slamon & A. Ullrich: Smart drugs: Tyrosine kinase inhibitors in cancer therapy. Cancer Cell 1, 117-123. (2002)
-
(2002)
Cancer Cell
, vol.1
, pp. 117-123
-
-
Shawver, L.K.1
Slamon, D.2
Ullrich, A.3
-
108
-
-
0029837306
-
Tyrphostin AG 1478 preferentially inhibits human glioma cells expressing truncated rather than wild-type epidermal growth factor receptors
-
Y. Han, C. G. Caday, A. Nanda, W. K. Cavenee & H. J. Huang: Tyrphostin AG 1478 preferentially inhibits human glioma cells expressing truncated rather than wild-type epidermal growth factor receptors. Cancer Res 56, 3859-3861. (1996)
-
(1996)
Cancer Res
, vol.56
, pp. 3859-3861
-
-
Han, Y.1
Caday, C.G.2
Nanda, A.3
Cavenee, W.K.4
Huang, H.J.5
-
109
-
-
0034486406
-
On receptor inhibitors and chemotherapy
-
P. D. Ryan & B. A. Chabner: On receptor inhibitors and chemotherapy. Clin Cancer Res 6, 4607-4609. (2000)
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4607-4609
-
-
Ryan, P.D.1
Chabner, B.A.2
-
111
-
-
0036141447
-
Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling
-
A. Chakravarti, J. S. Loeffler & N. J. Dyson: Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling. Cancer Res 62, 200-207. (2002)
-
(2002)
Cancer Res
, vol.62
, pp. 200-207
-
-
Chakravarti, A.1
Loeffler, J.S.2
Dyson, N.J.3
-
112
-
-
0018125603
-
Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial
-
M. D. Walker, E. Alexander, Jr., W. E. Hunt, C. S. MacCarty, M. S. Mahaley, Jr., J. Mealey, Jr., H. A. Norrell, G. Owens, J. Ransohoff, C. B. Wilson, E. A. Gehan & T. A. Strike: Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial. J Neurosurg 49, 333-343. (1978)
-
(1978)
J Neurosurg
, vol.49
, pp. 333-343
-
-
Walker, M.D.1
Alexander Jr., E.2
Hunt, W.E.3
MacCarty, C.S.4
Mahaley Jr., M.S.5
Mealey Jr., J.6
Norrell, H.A.7
Owens, G.8
Ransohoff, J.9
Wilson, C.B.10
Gehan, E.A.11
Strike, T.A.12
-
113
-
-
0035479296
-
EGFR overexpression and radiation response in glioblastoma multiforme
-
F. G. Barker, 2nd, M. L. Simmons, S. M. Chang, M. D. Prados, D. A. Larson, P. K. Sneed, W. M. Wara, M. S. Berger, P. Chen, M. A. Israel & K. D. Aldape: EGFR overexpression and radiation response in glioblastoma multiforme. Int J Radiat Oncol Biol Phys 51, 410-418. (2001)
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.51
, pp. 410-418
-
-
Barker II, F.G.1
Simmons, M.L.2
Chang, S.M.3
Prados, M.D.4
Larson, D.A.5
Sneed, P.K.6
Wara, W.M.7
Berger, M.S.8
Chen, P.9
Israel, M.A.10
Aldape, K.D.11
-
114
-
-
0033970141
-
Modulation of molecular targets to enhance radiation
-
P. M. Harari & S. M. Huang: Modulation of molecular targets to enhance radiation. Clin Cancer Res 6, 323-325. (2000)
-
(2000)
Clin Cancer Res
, vol.6
, pp. 323-325
-
-
Harari, P.M.1
Huang, S.M.2
-
115
-
-
0032719534
-
Inverse relationship between epidermal growth factor receptor expression and radiocurability of murine carcinomas
-
T. Akimoto, N. R. Hunter, L. Buchmiller, K. Mason, K. K. Ang & L. Milas: Inverse relationship between epidermal growth factor receptor expression and radiocurability of murine carcinomas. Clin Cancer Res 5, 2884-2890. (1999)
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2884-2890
-
-
Akimoto, T.1
Hunter, N.R.2
Buchmiller, L.3
Mason, K.4
Ang, K.K.5
Milas, L.6
-
116
-
-
10244243722
-
Prognostic significance of epidermal growth factor receptor in laryngeal squamous cell carcinoma
-
M. Maurizi, G. Almadori, G. Ferrandina, M. Distefano, M. E. Romanini, G. Cadoni, P. Benedetti-Panici, G. Paludetti, G. Scambia & S. Mancuso: Prognostic significance of epidermal growth factor receptor in laryngeal squamous cell carcinoma. Br J Cancer 74, 1253-1257. (1996)
-
(1996)
Br J Cancer
, vol.74
, pp. 1253-1257
-
-
Maurizi, M.1
Almadori, G.2
Ferrandina, G.3
Distefano, M.4
Romanini, M.E.5
Cadoni, G.6
Benedetti-Panici, P.7
Paludetti, G.8
Scambia, G.9
Mancuso, S.10
-
117
-
-
0035880788
-
PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme
-
J. S. Smith, I. Tachibana, S. M. Passe, B. K. Huntley, T. J. Borell, N. Iturria, J. R. O'Fallon, P. L. Schaefer, B. W. Scheithauer, C. D. James, J. C. Buckner & R. B. Jenkins: PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme. J Natl Cancer Inst 93, 1246-1256. (2001)
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 1246-1256
-
-
Smith, J.S.1
Tachibana, I.2
Passe, S.M.3
Huntley, B.K.4
Borell, T.J.5
Iturria, N.6
O'Fallon, J.R.7
Schaefer, P.L.8
Scheithauer, B.W.9
James, C.D.10
Buckner, J.C.11
Jenkins, R.B.12
-
118
-
-
0042456000
-
Tumour-proliferative fraction and growth factor expression as markers of tumour response to radiotherapy in cancer of the uterine cervix
-
M. R. Pillai, P. G. Jayaprakash & M. K. Nair: Tumour-proliferative fraction and growth factor expression as markers of tumour response to radiotherapy in cancer of the uterine cervix. J Cancer Res Clin Oncol 124, 456-461 (1998)
-
(1998)
J Cancer Res Clin Oncol
, vol.124
, pp. 456-461
-
-
Pillai, M.R.1
Jayaprakash, P.G.2
Nair, M.K.3
-
119
-
-
0029983510
-
Epidermal growth factor receptor: An independent predictor of survival in astrocytic tumors given definitive irradiation
-
A. Zhu, J. Shaeffer, S. Leslie, P. Kolm & A. M. El-Mahdi: Epidermal growth factor receptor: an independent predictor of survival in astrocytic tumors given definitive irradiation. Int J Radiat Oncol Biol Phys 34, 809-815. (1996)
-
(1996)
Int J Radiat Oncol Biol Phys
, vol.34
, pp. 809-815
-
-
Zhu, A.1
Shaeffer, J.2
Leslie, S.3
Kolm, P.4
El-Mahdi, A.M.5
-
120
-
-
0029589572
-
Radiation-induced enhanced proliferation of human squamous cancer cells in vitro: A release from inhibition by epidermal growth factor
-
B. D. Kavanagh, P. S. Lin, P. Chen & R. K. Schmidt-Ullrich: Radiation-induced enhanced proliferation of human squamous cancer cells in vitro: a release from inhibition by epidermal growth factor. Clin Cancer Res 1, 1557-1562. (1995)
-
(1995)
Clin Cancer Res
, vol.1
, pp. 1557-1562
-
-
Kavanagh, B.D.1
Lin, P.S.2
Chen, P.3
Schmidt-Ullrich, R.K.4
-
121
-
-
0030042135
-
Radiation-induced autophosphorylation of epidermal growth factor receptor in human malignant mammary and squamous epithelial cells
-
R. K. Schmidt-Ullrich, K. Valerie, P. B. Fogleman & J. Walters: Radiation-induced autophosphorylation of epidermal growth factor receptor in human malignant mammary and squamous epithelial cells. Radiat Res 145, 81-85. (1996)
-
(1996)
Radiat Res
, vol.145
, pp. 81-85
-
-
Schmidt-Ullrich, R.K.1
Valerie, K.2
Fogleman, P.B.3
Walters, J.4
-
122
-
-
0000091450
-
The effect of ionizing radiation on signal transduction: Antibodies to EGF receptor sensitize A431 cells to radiation
-
N. Balaban, J. Moni, M. Shannon, L. Dang, E. Murphy & T. Goldkorn: The effect of ionizing radiation on signal transduction: antibodies to EGF receptor sensitize A431 cells to radiation. Biochim Biophys Acta 1314, 147-156. (1996)
-
(1996)
Biochim Biophys Acta
, vol.1314
, pp. 147-156
-
-
Balaban, N.1
Moni, J.2
Shannon, M.3
Dang, L.4
Murphy, E.5
Goldkorn, T.6
-
124
-
-
0030772168
-
Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation
-
R. K. Schmidt-Ullrich, R. B. Mikkelsen, P. Dent, D. G. Todd, K. Valerie, B. D. Kavanagh, J. N. Contessa, W. K. Rorrer & P. B. Chen: Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation. Oncogene 15, 1191-1197. (1997)
-
(1997)
Oncogene
, vol.15
, pp. 1191-1197
-
-
Schmidt-Ullrich, R.K.1
Mikkelsen, R.B.2
Dent, P.3
Todd, D.G.4
Valerie, K.5
Kavanagh, B.D.6
Contessa, J.N.7
Rorrer, W.K.8
Chen, P.B.9
-
125
-
-
0032815618
-
Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death
-
P. Dent, D. B. Reardon, J. S. Park, G. Bowers, C. Logsdon, K. Valerie & R. Schmidt-Ullrich: Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death. Mol Biol Cell 10, 2493-2506. (1999)
-
(1999)
Mol Biol Cell
, vol.10
, pp. 2493-2506
-
-
Dent, P.1
Reardon, D.B.2
Park, J.S.3
Bowers, G.4
Logsdon, C.5
Valerie, K.6
Schmidt-Ullrich, R.7
-
126
-
-
0029790979
-
Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents
-
A. Knebel, H. J. Rahmsdorf, A. Ullrich & P. Herrlich: Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents. Embo J 15, 5314-5325. (1996)
-
(1996)
Embo J
, vol.15
, pp. 5314-5325
-
-
Knebel, A.1
Rahmsdorf, H.J.2
Ullrich, A.3
Herrlich, P.4
-
127
-
-
0035866813
-
Sublethal irradiation promotes migration and invasiveness of glioma cells: Implications for radiotherapy of human glioblastoma
-
C. Wild-Bode, M. Weller, A. Rimner, J. Dichgans & W. Wick: Sublethal irradiation promotes migration and invasiveness of glioma cells: implications for radiotherapy of human glioblastoma. Cancer Res 61, 2744-2750. (2001)
-
(2001)
Cancer Res
, vol.61
, pp. 2744-2750
-
-
Wild-Bode, C.1
Weller, M.2
Rimner, A.3
Dichgans, J.4
Wick, W.5
-
128
-
-
0034059884
-
Signal transduction and cellular radiation responses
-
R. K. Schmidt-Ullrich, P. Dent, S. Grant, R. B. Mikkelsen & K. Valerie: Signal transduction and cellular radiation responses. Radiat Res 153, 245-257. (2000)
-
(2000)
Radiat Res
, vol.153
, pp. 245-257
-
-
Schmidt-Ullrich, R.K.1
Dent, P.2
Grant, S.3
Mikkelsen, R.B.4
Valerie, K.5
-
129
-
-
17344382185
-
Combined modality therapy of A431 human epidermoid cancer using anti- EGFr antibody C225 and radiation
-
M. N. Saleh, K. P. Raisch, M. A. Stackhouse, W. E. Grizzle, J. A. Bonner, M. S. Mayo, H. G. Kim, R. F. Meredith, R. H. Wheeler & D. J. Buchsbaum: Combined modality therapy of A431 human epidermoid cancer using anti- EGFr antibody C225 and radiation. Cancer Biother Radiopharm 14, 451-463. (1999)
-
(1999)
Cancer Biother Radiopharm
, vol.14
, pp. 451-463
-
-
Saleh, M.N.1
Raisch, K.P.2
Stackhouse, M.A.3
Grizzle, W.E.4
Bonner, J.A.5
Mayo, M.S.6
Kim, H.G.7
Meredith, R.F.8
Wheeler, R.H.9
Buchsbaum, D.J.10
-
130
-
-
0033561522
-
Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck
-
S. M. Huang, J. M. Bock & P. M. Harari: Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck. Cancer Res 59, 1935-1940. (1999)
-
(1999)
Cancer Res
, vol.59
, pp. 1935-1940
-
-
Huang, S.M.1
Bock, J.M.2
Harari, P.M.3
-
131
-
-
0035254521
-
Head and neck cancer as a clinical model for molecular targeting of therapy: Combining EGFR blockade with radiation
-
P. M. Harari & S. M. Huang: Head and neck cancer as a clinical model for molecular targeting of therapy: combining EGFR blockade with radiation. Int J Radiat Oncol Biol Phys 49, 427-433. (2001)
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.49
, pp. 427-433
-
-
Harari, P.M.1
Huang, S.M.2
-
132
-
-
0033748391
-
Antitumor activity of combined treatment of human cancer cells with ionizing radiation and anti-epidermal growth factor receptor monoclonal antibody C225 plus type I protein kinase a antisense oligonucleotide
-
C. Bianco, R. Bianco, G. Tortora, V. Damiano, P. Guerrieri, P. Montemaggi, J. Mendelsohn, S. De Placido, A. R. Bianco & F. Ciardiello: Antitumor activity of combined treatment of human cancer cells with ionizing radiation and anti-epidermal growth factor receptor monoclonal antibody C225 plus type I protein kinase A antisense oligonucleotide. Clin Cancer Res 6, 4343-4350. (2000)
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4343-4350
-
-
Bianco, C.1
Bianco, R.2
Tortora, G.3
Damiano, V.4
Guerrieri, P.5
Montemaggi, P.6
Mendelsohn, J.7
De Placido, S.8
Bianco, A.R.9
Ciardiello, F.10
-
133
-
-
0034084314
-
Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: Inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis
-
S. M. Huang & P. M. Harari: Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis. Clin Cancer Res 6, 2166-2174. (2000)
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2166-2174
-
-
Huang, S.M.1
Harari, P.M.2
-
134
-
-
0033966576
-
In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody
-
L. Milas, K. Mason, N. Hunter, S. Petersen, M. Yamakawa, K. Ang, J. Mendelsohn & Z. Fan: In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody. Clin Cancer Res 6, 701-708. (2000)
-
(2000)
Clin Cancer Res
, vol.6
, pp. 701-708
-
-
Milas, L.1
Mason, K.2
Hunter, N.3
Petersen, S.4
Yamakawa, M.5
Ang, K.6
Mendelsohn, J.7
Fan, Z.8
-
135
-
-
0035479052
-
C225 antiepidermal growth factor receptor antibody enhances tumor radiocurability
-
S. Nasu, K. K. Ang, Z. Fan & L. Milas: C225 antiepidermal growth factor receptor antibody enhances tumor radiocurability. Int J Radiat Oncol Biol Phys 51, 474-477. (2001)
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.51
, pp. 474-477
-
-
Nasu, S.1
Ang, K.K.2
Fan, Z.3
Milas, L.4
-
136
-
-
0001166676
-
Treatment of human intracranial gliomas with chimeric monoclonal antibody against epidermal growth factor receptor increases survival of nude mice when treated concurrently with irradiation
-
abst
-
D. Raben, D. J. Buchsbaum, G. Y. Gillespie & et. al.: Treatment of human intracranial gliomas with chimeric monoclonal antibody against epidermal growth factor receptor increases survival of nude mice when treated concurrently with irradiation. Proc Am Assoc Cancer 40, A1224 (abst) (1999)
-
(1999)
Proc Am Assoc Cancer
, vol.40
-
-
Raben, D.1
Buchsbaum, D.J.2
Gillespie, G.Y.3
-
137
-
-
0034029550
-
Ionizing radiation-induced mitogen-activated protein (MAP) kinase activation in DU145 prostate carcinoma cells: MAP kinase inhibition enhances radiation-induced cell killing and G2/M-phase arrest
-
M. Hagan, L. Wang, J. R. Hanley, J. S. Park & P. Dent: Ionizing radiation-induced mitogen-activated protein (MAP) kinase activation in DU145 prostate carcinoma cells: MAP kinase inhibition enhances radiation-induced cell killing and G2/M-phase arrest. Radiat Res 153, 371-383. (2000)
-
(2000)
Radiat Res
, vol.153
, pp. 371-383
-
-
Hagan, M.1
Wang, L.2
Hanley, J.R.3
Park, J.S.4
Dent, P.5
-
138
-
-
0036005846
-
ZD1839, a selective epidermal growth factor receptor tyrosine kinase inhibitor, alone and in combination with radiation and chemotherapy as a new therapeutic strategy in non-small cell lung cancer
-
D. Raben, B. A. Helfrich, D. Chan, G. Johnson & P. A. Bunn, Jr.: ZD1839, a selective epidermal growth factor receptor tyrosine kinase inhibitor, alone and in combination with radiation and chemotherapy as a new therapeutic strategy in non-small cell lung cancer. Semin Oncol 29, 37-46. (2002)
-
(2002)
Semin Oncol
, vol.29
, pp. 37-46
-
-
Raben, D.1
Helfrich, B.A.2
Chan, D.3
Johnson, G.4
Bunn Jr., P.A.5
-
139
-
-
0035918858
-
Epidermal growth factor receptor as a genetic therapy target for carcinoma cell radiosensitization
-
G. Lammering, T. H. Hewit, W. T. Hawkins, J. N. Contessa, D. B. Reardon, P. S. Lin, K. Valerie, P. Dent, R. B. Mikkelsen & R. K. Schmidt-Ullrich: Epidermal growth factor receptor as a genetic therapy target for carcinoma cell radiosensitization. J Natl Cancer Inst 93, 921-929. (2001)
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 921-929
-
-
Lammering, G.1
Hewit, T.H.2
Hawkins, W.T.3
Contessa, J.N.4
Reardon, D.B.5
Lin, P.S.6
Valerie, K.7
Dent, P.8
Mikkelsen, R.B.9
Schmidt-Ullrich, R.K.10
-
140
-
-
0003131542
-
Repair of radiation damage and the dose-rate effect
-
Eds: E. J. Hall. Lippincott Williams & wilkins, Philadelphia
-
E. J. Hall: Repair of radiation damage and the dose-rate effect. In: Radiobiology for the radiologist. Eds: E. J. Hall. Lippincott Williams & wilkins, Philadelphia 67-90 (2000)
-
(2000)
Radiobiology for the Radiologist
, pp. 67-90
-
-
Hall, E.J.1
-
141
-
-
0024580323
-
Effect of antisense c-raf-1 on tumorigenicity and radiation sensitivity of a human squamous carcinoma
-
U. Kasid, A. Pfeifer, T. Brennan, M. Beckett, R. R. Weichselbaum, A. Dritschilo & G. E. Mark: Effect of antisense c-raf-1 on tumorigenicity and radiation sensitivity of a human squamous carcinoma. Science 243, 1354-1356. (1989)
-
(1989)
Science
, vol.243
, pp. 1354-1356
-
-
Kasid, U.1
Pfeifer, A.2
Brennan, T.3
Beckett, M.4
Weichselbaum, R.R.5
Dritschilo, A.6
Mark, G.E.7
-
142
-
-
0035872443
-
The Ras radiation resistance pathway
-
A. K. Gupta, V. J. Bakanauskas, G. J. Cerniglia, Y. Cheng, E. J. Bernhard, R. J. Muschel & W. G. McKenna: The Ras radiation resistance pathway. Cancer Res 61, 4278-4282. (2001)
-
(2001)
Cancer Res
, vol.61
, pp. 4278-4282
-
-
Gupta, A.K.1
Bakanauskas, V.J.2
Cerniglia, G.J.3
Cheng, Y.4
Bernhard, E.J.5
Muschel, R.J.6
McKenna, W.G.7
-
143
-
-
0024354928
-
raf involvement in the simultaneous genetic transfer of the radioresistant and transforming phenotypes
-
K. F. Pirollo, R. Garner, S. Y. Yuan, L. Li, W. A. Blattner & E. H. Chang: raf involvement in the simultaneous genetic transfer of the radioresistant and transforming phenotypes. Int J Radiat Biol 55, 783-796. (1989)
-
(1989)
Int J Radiat Biol
, vol.55
, pp. 783-796
-
-
Pirollo, K.F.1
Garner, R.2
Yuan, S.Y.3
Li, L.4
Blattner, W.A.5
Chang, E.H.6
-
144
-
-
0025282789
-
The role of the H-ras oncogene in radiation resistance and metastasis
-
W. G. McKenna, M. C. Weiss, V. J. Bakanauskas, H. Sandler, M. L. Kelsten, J. Biaglow, S. W. Tuttle, B. Endlich, C. C. Ling & R. J. Muschel: The role of the H-ras oncogene in radiation resistance and metastasis. Int J Radiat Oncol Biol Phys 18, 849-859. (1990)
-
(1990)
Int J Radiat Oncol Biol Phys
, vol.18
, pp. 849-859
-
-
McKenna, W.G.1
Weiss, M.C.2
Bakanauskas, V.J.3
Sandler, H.4
Kelsten, M.L.5
Biaglow, J.6
Tuttle, S.W.7
Endlich, B.8
Ling, C.C.9
Muschel, R.J.10
-
146
-
-
0031891006
-
Physical interaction between epidermal growth factor receptor and DNA- Dependent protein kinase in mammalian cells
-
D. Bandyopadhyay, M. Mandal, L. Adam, J. Mendelsohn & R. Kumar: Physical interaction between epidermal growth factor receptor and DNA- dependent protein kinase in mammalian cells. J Biol Chem 273, 1568-1573. (1998)
-
(1998)
J Biol Chem
, vol.273
, pp. 1568-1573
-
-
Bandyopadhyay, D.1
Mandal, M.2
Adam, L.3
Mendelsohn, J.4
Kumar, R.5
-
147
-
-
0000598906
-
Time, dose, and fractionation in radiotherapy
-
Eds: E. J. Hall. Lippincott Williams & Wilkins, Philadelphia
-
E. J. Hall: Time, dose, and fractionation in radiotherapy. In: Radiobiology for the radiologist. Eds: E. J. Hall. Lippincott Williams & Wilkins, Philadelphia 397-418 (2000)
-
(2000)
Radiobiology for the Radiologist
, pp. 397-418
-
-
Hall, E.J.1
-
148
-
-
0026636951
-
Loss of local control with prolongation in radiotherapy
-
J. F. Fowler & M. J. Lindstrom: Loss of local control with prolongation in radiotherapy. Int J Radiat Oncol Biol Phys 23, 457-467 (1992)
-
(1992)
Int J Radiat Oncol Biol Phys
, vol.23
, pp. 457-467
-
-
Fowler, J.F.1
Lindstrom, M.J.2
-
149
-
-
0029103337
-
The adverse effect of treatment prolongation in cervical carcinoma
-
D. G. Petereit, J. N. Sarkaria, R. Chappell, J. F. Fowler, T. J. Hartmann, T. J. Kinsella, J. A. Stitt, B. R. Thomadsen & D. A. Buchler: The adverse effect of treatment prolongation in cervical carcinoma. Int J Radiat Oncol Biol Phys 32, 1301-1307. (1995)
-
(1995)
Int J Radiat Oncol Biol Phys
, vol.32
, pp. 1301-1307
-
-
Petereit, D.G.1
Sarkaria, J.N.2
Chappell, R.3
Fowler, J.F.4
Hartmann, T.J.5
Kinsella, T.J.6
Stitt, J.A.7
Thomadsen, B.R.8
Buchler, D.A.9
-
150
-
-
0026676867
-
The effect of treatment duration in the local control of cervix cancer
-
A. Fyles, T. J. Keane, M. Barton & J. Simm: The effect of treatment duration in the local control of cervix cancer. Radiother Oncol 25, 273-279. (1992)
-
(1992)
Radiother Oncol
, vol.25
, pp. 273-279
-
-
Fyles, A.1
Keane, T.J.2
Barton, M.3
Simm, J.4
-
151
-
-
0027457109
-
The influence of treatment time on outcome for squamous cell cancer of the uterine cervix treated with radiation: A patterns-of-care study
-
R. M. Lanciano, T. F. Pajak, K. Martz & G. E. Hanks: The influence of treatment time on outcome for squamous cell cancer of the uterine cervix treated with radiation: a patterns-of-care study. Int J Radiat Oncol Biol Phys 25, 391-397. (1993)
-
(1993)
Int J Radiat Oncol Biol Phys
, vol.25
, pp. 391-397
-
-
Lanciano, R.M.1
Pajak, T.F.2
Martz, K.3
Hanks, G.E.4
-
152
-
-
0023894783
-
The hazard of accelerated tumor clonogen repopulation during radiotherapy
-
H. R. Withers, J. M. Taylor & B. Maciejewski: The hazard of accelerated tumor clonogen repopulation during radiotherapy. Acta Oncol 27, 131-146 (1988)
-
(1988)
Acta Oncol
, vol.27
, pp. 131-146
-
-
Withers, H.R.1
Taylor, J.M.2
Maciejewski, B.3
-
153
-
-
0030452095
-
Tissue kinetics in mouse tongue mucosa during daily fractionated radiotherapy
-
W. Dorr, H. Emmendorfer & M. Weber-Frisch: Tissue kinetics in mouse tongue mucosa during daily fractionated radiotherapy. Cell Prolif 29, 495-504. (1996)
-
(1996)
Cell Prolif
, vol.29
, pp. 495-504
-
-
Dorr, W.1
Emmendorfer, H.2
Weber-Frisch, M.3
-
154
-
-
0030006440
-
Changes in keratinocyte differentiation during accelerated repopulation of the irradiated mouse epidermis
-
K. Liu, M. Kasper & K. R. Trott: Changes in keratinocyte differentiation during accelerated repopulation of the irradiated mouse epidermis. Int J Radiat Biol 69, 763-769. (1996)
-
(1996)
Int J Radiat Biol
, vol.69
, pp. 763-769
-
-
Liu, K.1
Kasper, M.2
Trott, K.R.3
-
155
-
-
0028920514
-
The decreased influence of overall treatment time on the response of human breast tumor xenografts following prolongation of the potential doubling time (Tpot)
-
J. N. Sarkaria, J. F. Fowler, M. J. Lindstrom, V. C. Jordan & R. T. Mulcahy: The decreased influence of overall treatment time on the response of human breast tumor xenografts following prolongation of the potential doubling time (Tpot). Int J Radiat Oncol Biol Phys 31, 833-840. (1995)
-
(1995)
Int J Radiat Oncol Biol Phys
, vol.31
, pp. 833-840
-
-
Sarkaria, J.N.1
Fowler, J.F.2
Lindstrom, M.J.3
Jordan, V.C.4
Mulcahy, R.T.5
-
156
-
-
0033398661
-
Molecular mechanisms of radiation-induced accelerated repopulation
-
R. K. Schmidt-Ullrich, J. N. Contessa, P. Dent, R. B. Mikkelsen, K. Valerie, D. B. Reardon, G. Bowers & P. S. Lin: Molecular mechanisms of radiation-induced accelerated repopulation. Radiat Oncol Investig 7, 321-330 (1999)
-
(1999)
Radiat Oncol Investig
, vol.7
, pp. 321-330
-
-
Schmidt-Ullrich, R.K.1
Contessa, J.N.2
Dent, P.3
Mikkelsen, R.B.4
Valerie, K.5
Reardon, D.B.6
Bowers, G.7
Lin, P.S.8
-
157
-
-
0035555907
-
Effect of VEGF receptor inhibitor PTK787/ZK222584 (correction of ZK222548) combined with ionizing radiation on endothelial cells and tumour growth
-
C. Hess, V. Vuong, I. Hegyi, O. Riesterer, J. Wood, D. Fabbro, C. Glanzmann, S. Bodis & M. Pruschy: Effect of VEGF receptor inhibitor PTK787/ZK222584 (correction of ZK222548) combined with ionizing radiation on endothelial cells and tumour growth. Br J Cancer 85, 2010-2016. (2001)
-
(2001)
Br J Cancer
, vol.85
, pp. 2010-2016
-
-
Hess, C.1
Vuong, V.2
Hegyi, I.3
Riesterer, O.4
Wood, J.5
Fabbro, D.6
Glanzmann, C.7
Bodis, S.8
Pruschy, M.9
-
158
-
-
0036145292
-
The antiangiogenic agents SU5416 and SU6668 increase the antitumor effects of fractionated irradiation
-
S. Ning, D. Laird, J. M. Cherrington & S. J. Knox: The antiangiogenic agents SU5416 and SU6668 increase the antitumor effects of fractionated irradiation. Radiat Res 157, 45-51. (2002)
-
(2002)
Radiat Res
, vol.157
, pp. 45-51
-
-
Ning, S.1
Laird, D.2
Cherrington, J.M.3
Knox, S.J.4
-
159
-
-
0035866771
-
Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy
-
L. Geng, E. Donnelly, G. McMahon, P. C. Lin, E. Sierra-Rivera, H. Oshinka & D. E. Hallahan: Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy. Cancer Res 61, 2413-2419. (2001)
-
(2001)
Cancer Res
, vol.61
, pp. 2413-2419
-
-
Geng, L.1
Donnelly, E.2
McMahon, G.3
Lin, P.C.4
Sierra-Rivera, E.5
Oshinka, H.6
Hallahan, D.E.7
-
160
-
-
0034099423
-
Therapeutic synergy of TNP-470 and ionizing radiation: Effects on tumor growth, vessel morphology, and angiogenesis in human glioblastoma multiforme xenografts
-
E. L. Lund, L. Bastholm & P. E. Kristjansen: Therapeutic synergy of TNP-470 and ionizing radiation: effects on tumor growth, vessel morphology, and angiogenesis in human glioblastoma multiforme xenografts. Clin Cancer Res 6, 971-978. (2000)
-
(2000)
Clin Cancer Res
, vol.6
, pp. 971-978
-
-
Lund, E.L.1
Bastholm, L.2
Kristjansen, P.E.3
-
161
-
-
0033564974
-
Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation
-
D. H. Gorski, M. A. Beckett, N. T. Jaskowiak, D. P. Calvin, H. J. Mauceri, R. M. Salloum, S. Seetharam, A. Koons, D. M. Hari, D. W. Kufe & R. R. Weichselbaum: Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation. Cancer Res 59, 3374-3378. (1999)
-
(1999)
Cancer Res
, vol.59
, pp. 3374-3378
-
-
Gorski, D.H.1
Beckett, M.A.2
Jaskowiak, N.T.3
Calvin, D.P.4
Mauceri, H.J.5
Salloum, R.M.6
Seetharam, S.7
Koons, A.8
Hari, D.M.9
Kufe, D.W.10
Weichselbaum, R.R.11
-
162
-
-
17444376781
-
Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin
-
D. H. Gorski, H. J. Mauceri, R. M. Salloum, S. Gately, S. Hellman, M. A. Beckett, V. P. Sukhatme, G. A. Soff, D. W. Kufe & R. R. Weichselbaum: Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin. Cancer Res 58, 5686-5689. (1998)
-
(1998)
Cancer Res
, vol.58
, pp. 5686-5689
-
-
Gorski, D.H.1
Mauceri, H.J.2
Salloum, R.M.3
Gately, S.4
Hellman, S.5
Beckett, M.A.6
Sukhatme, V.P.7
Soff, G.A.8
Kufe, D.W.9
Weichselbaum, R.R.10
-
163
-
-
0030869787
-
Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras- Transformed cells through a hypoxia inducible factor-1 transcriptional element
-
N. M. Mazure, E. Y. Chen, K. R. Laderoute & A. J. Giaccia: Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras- transformed cells through a hypoxia inducible factor-1 transcriptional element. Blood 90, 3322-3331. (1997)
-
(1997)
Blood
, vol.90
, pp. 3322-3331
-
-
Mazure, N.M.1
Chen, E.Y.2
Laderoute, K.R.3
Giaccia, A.J.4
-
164
-
-
0034654174
-
Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics
-
H. Zhong, K. Chiles, D. Feldser, E. Laughner, C. Hanrahan, M. M. Georgescu, J. W. Simons & G. L. Semenza: Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics. Cancer Res 60, 1541-1545. (2000)
-
(2000)
Cancer Res
, vol.60
, pp. 1541-1545
-
-
Zhong, H.1
Chiles, K.2
Feldser, D.3
Laughner, E.4
Hanrahan, C.5
Georgescu, M.M.6
Simons, J.W.7
Semenza, G.L.8
-
165
-
-
0036359548
-
Hypoxia - A key regulatory factor in tumour growth
-
A. L. Harris: Hypoxia - a key regulatory factor in tumour growth. Nature Rev Cancer 2, 38-47. (2002)
-
(2002)
Nature Rev Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
168
-
-
0033067279
-
Vascular endothelial growth factor expression, vascular volume, and, capillary permeability in human brain tumors
-
M. R. Machein, J. Kullmer, B. L. Fiebich, K. H. Plate & P. C. Warnke: Vascular endothelial growth factor expression, vascular volume, and, capillary permeability in human brain tumors. Neurosurgery 44, 732-740; discussion 740-731. (1999)
-
(1999)
Neurosurgery
, vol.44
, pp. 732-740
-
-
Machein, M.R.1
Kullmer, J.2
Fiebich, B.L.3
Plate, K.H.4
Warnke, P.C.5
-
169
-
-
0030772252
-
Vascular endothelial growth factor
-
K. H. Plate & P. C. Warnke: Vascular endothelial growth factor. J Neurooncol 35, 365-372. (1997)
-
(1997)
J Neurooncol
, vol.35
, pp. 365-372
-
-
Plate, K.H.1
Warnke, P.C.2
-
171
-
-
0344512505
-
Radiosensitivity and cell age in the mitotic cycle
-
Eds: E. J. Hall. Philadelphia
-
E. J. Hall: Radiosensitivity and cell age in the mitotic cycle. In: Radiobiology for the radiologist. Eds: E. J. Hall. Philadelphia 51-66 (2000)
-
(2000)
Radiobiology for the Radiologist
, pp. 51-66
-
-
Hall, E.J.1
-
172
-
-
0034329308
-
Enhanced apoptosis with combination C225/radiation treatment serves as the impetus for clinical investigation in head and neck cancers
-
J. A. Bonner, K. P. Raisch, H. Q. Trummell, F. Robert, R. F. Meredith, S. A. Spencer, D. J. Buchsbaum, M. N. Saleh, M. A. Stackhouse, A. F. LoBuglio, G. E. Peters, W. R. Carroll & H. W. Waksal: Enhanced apoptosis with combination C225/radiation treatment serves as the impetus for clinical investigation in head and neck cancers. J Clin Oncol 18, 47S-53S. (2000)
-
(2000)
J Clin Oncol
, vol.18
-
-
Bonner, J.A.1
Raisch, K.P.2
Trummell, H.Q.3
Robert, F.4
Meredith, R.F.5
Spencer, S.A.6
Buchsbaum, D.J.7
Saleh, M.N.8
Stackhouse, M.A.9
Lobuglio, A.F.10
Peters, G.E.11
Carroll, W.R.12
Waksal, H.W.13
|