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Volumn 86, Issue 2, 2000, Pages 269-275

Recombinant antibody toxins specific for ErbB2 and EGF receptor inhibit the in vitro growth of human head and neck cancer cells and cause rapid tumor regression in vivo

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE; RECOMBINANT ANTIBODY;

EID: 0034087465     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(20000415)86:2<269::AID-IJC18>3.0.CO;2-8     Document Type: Article
Times cited : (99)

References (20)
  • 1
    • 0030873969 scopus 로고    scopus 로고
    • Targeted therapy of schwannoma cells in immunocompetent rats with an erbB2-specific antibody toxin
    • ALTENSCHMIDT, U., SCHMIDT, M., GRONER, B. and WELS, W., Targeted therapy of schwannoma cells in immunocompetent rats with an erbB2-specific antibody toxin. Int. J. Cancer, 73, 117-124 (1997).
    • (1997) Int. J. Cancer , vol.73 , pp. 117-124
    • Altenschmidt, U.1    Schmidt, M.2    Groner, B.3    Wels, W.4
  • 3
    • 0031974705 scopus 로고    scopus 로고
    • Therapeutic application of anti-growth factor receptor antibodies
    • FAN, Z. and MENDELSOHN, J., Therapeutic application of anti-growth factor receptor antibodies. Curr. Opin. Oncol., 10, 67-73 (1998).
    • (1998) Curr. Opin. Oncol. , vol.10 , pp. 67-73
    • Fan, Z.1    Mendelsohn, J.2
  • 6
    • 0023657391 scopus 로고
    • Functional domains of Pseudomonasexotoxin identified by deletion analysis of the gene expressed in E. Coli
    • HWANG, J., FITZGERALD, D.J., ADHYA, S. and PASTAN, I., Functional domains of Pseudomonasexotoxin identified by deletion analysis of the gene expressed in E. coli. Cell, 48, 129-136 (1987).
    • (1987) Cell , vol.48 , pp. 129-136
    • Hwang, J.1    Fitzgerald, D.J.2    Adhya, S.3    Pastan, I.4
  • 7
    • 0024516756 scopus 로고
    • Overexpression of the c-erbB-2 protein in human breast tumor cell lines
    • HYNES, N.E., GERBER, H.A., SAURER, S. and GRONER, B., Overexpression of the c-erbB-2 protein in human breast tumor cell lines. J. cell. Biochem., 39, 167-173 (1989).
    • (1989) J. Cell. Biochem. , vol.39 , pp. 167-173
    • Hynes, N.E.1    Gerber, H.A.2    Saurer, S.3    Groner, B.4
  • 8
    • 0031426819 scopus 로고    scopus 로고
    • Expression of c-erbb proto-oncogene family members in squamous cell carcinoma of the head and neck
    • IBRAHIM, S.O., VASSTRAND, E.N., LIAVAAG, P.G., JOHANNESSEN, A.C. and LILLEHAUG, J.R., Expression of c-erbB proto-oncogene family members in squamous cell carcinoma of the head and neck. Anticancer Res., 17, 4539-4546 (1997).
    • (1997) Anticancer Res. , vol.17 , pp. 4539-4546
    • Ibrahim, S.O.1    Vasstrand, E.N.2    Liavaag, P.G.3    Johannessen, A.C.4    Lillehaug, J.R.5
  • 9
    • 0029812091 scopus 로고    scopus 로고
    • Intracellular expression of a single-chain antibody directed to the EGFR leads to growth inhibition of tumor cells
    • JANNOT, C.B., BEERLI, R.R., MASON, S., GULLICK, W.J. and HYNES, N.E., Intracellular expression of a single-chain antibody directed to the EGFR leads to growth inhibition of tumor cells. Oncogene, 13, 275-282 (1996).
    • (1996) Oncogene , vol.13 , pp. 275-282
    • Jannot, C.B.1    Beerli, R.R.2    Mason, S.3    Gullick, W.J.4    Hynes, N.E.5
  • 10
    • 0025359146 scopus 로고
    • Expression of the HER-2/neu proto-oncogene in normal human adult and fetal tissues
    • PRESS, M.F., CORDON-CARDO, C. and SLAMON, D.J., Expression of the HER-2/neu proto-oncogene in normal human adult and fetal tissues. Oncogene, 5, 953-962 (1990).
    • (1990) Oncogene , vol.5 , pp. 953-962
    • Press, M.F.1    Cordon-Cardo, C.2    Slamon, D.J.3
  • 11
    • 0022452615 scopus 로고
    • Expression of epidermal growth factor receptor in human cultured cells and tissues: Relationship to cell lineage and stage of differentiation
    • REAL, F.X., RETTIG, W.J., CHESA, P.G., MELAMED, M.R., OLD, L.J. and MENDELSOHN, J., Expression of epidermal growth factor receptor in human cultured cells and tissues: relationship to cell lineage and stage of differentiation. Cancer Res., 46, 4726-4731 (1986).
    • (1986) Cancer Res. , vol.46 , pp. 4726-4731
    • Real, F.X.1    Rettig, W.J.2    Chesa, P.G.3    Melamed, M.R.4    Old, L.J.5    Mendelsohn, J.6
  • 12
    • 0032403273 scopus 로고    scopus 로고
    • Recombinant fv immunotoxins and Fv fragments as novel agents for cancer therapy and diagnosis
    • REITER, Y. and PASTAN, I., Recombinant Fv immunotoxins and Fv fragments as novel agents for cancer therapy and diagnosis. Trends Biotechnol., 16, 513-520 (1998).
    • (1998) Trends Biotechnol. , vol.16 , pp. 513-520
    • Reiter, Y.1    Pastan, I.2
  • 13
    • 0025905507 scopus 로고
    • Comparative investigation of c-erbB2/neu expression in head and neck tumors and mammary cancer
    • RIVIERE, A., BECKER, J. and LONING, T., Comparative investigation of c-erbB2/neu expression in head and neck tumors and mammary cancer. Cancer, 67, 2142-2149 (1991).
    • (1991) Cancer , vol.67 , pp. 2142-2149
    • Riviere, A.1    Becker, J.2    Loning, T.3
  • 14
    • 0026061104 scopus 로고
    • Characterization, quantification, and potential clinical value of the epidermal growth factor receptor in head and neck squamous cell carcinomas
    • SANTINI, J., FORMENTO, J.L., FRANCOUAL, M., MILANO, G., SCHNEIDER, M., DASSONVILLE, O. and DEMARD, F., Characterization, quantification, and potential clinical value of the epidermal growth factor receptor in head and neck squamous cell carcinomas. Head Neck, 13, 132-139 (1991).
    • (1991) Head Neck , vol.13 , pp. 132-139
    • Santini, J.1    Formento, J.L.2    Francoual, M.3    Milano, G.4    Schneider, M.5    Dassonville, O.6    Demard, F.7
  • 15
    • 0031011597 scopus 로고    scopus 로고
    • Construction and functional characterization of scFv(14E1)-ETA - A novel, highly potent antibody toxin specific for the EGF receptor
    • SCHMIDT, M., VAKALOPOULOU, E., SCHNEIDER, D.W. and WELS, W., Construction and functional characterization of scFv(14E1)-ETA - a novel, highly potent antibody toxin specific for the EGF receptor. Brit. J. Cancer, 75, 1575-1584 (1997).
    • (1997) Brit. J. Cancer , vol.75 , pp. 1575-1584
    • Schmidt, M.1    Vakalopoulou, E.2    Schneider, D.W.3    Wels, W.4
  • 16
    • 0028985881 scopus 로고
    • EGF receptor and p185erbb-2-specific single-chain antibody toxins differ in their cell-killing activity on tumor cells expressing both receptor proteins
    • WELS, W., BEERLI, R., HELLMANN, P., SCHMIDT, M., MARTE, B.M., KORNILOVA, E.S., HEKELE, A., MENDELSOHN, J., GRONER, B. and HYNES, N.E., EGF receptor and p185erbB-2-specific single-chain antibody toxins differ in their cell-killing activity on tumor cells expressing both receptor proteins. Int. J. Cancer, 60, 137-144 (1995).
    • (1995) Int. J. Cancer , vol.60 , pp. 137-144
    • Wels, W.1    Beerli, R.2    Hellmann, P.3    Schmidt, M.4    Marte, B.M.5    Kornilova, E.S.6    Hekele, A.7    Mendelsohn, J.8    Groner, B.9    Hynes, N.E.10
  • 17
    • 0026486446 scopus 로고
    • Selective inhibition of tumor cell growth by a recombinant single-chain antibody toxin specific for the erbB-2 receptor
    • WELS, W., HARWERTH, I.M., MUELLER, M., GRONER, B. and HYNES, N.E., Selective inhibition of tumor cell growth by a recombinant single-chain antibody toxin specific for the erbB-2 receptor. Cancer Res., 52, 6310-6317 (1992).
    • (1992) Cancer Res. , vol.52 , pp. 6310-6317
    • Wels, W.1    Harwerth, I.M.2    Mueller, M.3    Groner, B.4    Hynes, N.E.5
  • 19
    • 0031041969 scopus 로고    scopus 로고
    • Strong correlation between c-erbB-2 overexpression and overall survival of patients with oral squamous cell carcinoma
    • XIA, W., LAU, Y.K., ZHANG, H.Z., LUI, A.R., LI, L., KIYOKAWA, N., CLAYMAN, G.L., KATZ, R.L. and HUNG, M.C., Strong correlation between c-erbB-2 overexpression and overall survival of patients with oral squamous cell carcinoma. Clin. Cancer Res., 3, 3-9 (1997).
    • (1997) Clin. Cancer Res. , vol.3 , pp. 3-9
    • Xia, W.1    Lau, Y.K.2    Zhang, H.Z.3    Lui, A.R.4    Li, L.5    Kiyokawa, N.6    Clayman, G.L.7    Katz, R.L.8    Hung, M.C.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.