-
1
-
-
0030760314
-
Crystal structure of human BPI and two bound phospholipids at 2.4 angstrom resolution
-
Beamer L.J., Carroll S.F., Eisenberg D. Crystal structure of human BPI and two bound phospholipids at 2.4 angstrom resolution. Science. 276:1997;1861-1864.
-
(1997)
Science
, vol.276
, pp. 1861-1864
-
-
Beamer, L.J.1
Carroll, S.F.2
Eisenberg, D.3
-
2
-
-
0031967690
-
The BPI/LBP family of proteins: A structural analysis of conserved regions
-
a
-
Beamer L.J., Carroll S.F., Eisenberg D. The BPI/LBP family of proteins. a structural analysis of conserved regions Protein Sci. 7:1998;906-914. a.
-
(1998)
Protein Sci.
, vol.7
, pp. 906-914
-
-
Beamer, L.J.1
Carroll, S.F.2
Eisenberg, D.3
-
3
-
-
0031872224
-
Detecting distant relatives of mammalian LPS-binding and lipid transport proteins
-
b
-
Beamer L.J., Fischer D., Eisenberg D. Detecting distant relatives of mammalian LPS-binding and lipid transport proteins. Protein Sci. 7:1998;1643-1646. b.
-
(1998)
Protein Sci.
, vol.7
, pp. 1643-1646
-
-
Beamer, L.J.1
Fischer, D.2
Eisenberg, D.3
-
4
-
-
0037439310
-
Lipopolysaccharide-binding protein serum levels in patients with severe sepsis due to gram-positive and fungal infections
-
Blairon L., Wittebole X., Laterre P.F. Lipopolysaccharide-binding protein serum levels in patients with severe sepsis due to gram-positive and fungal infections. J. Infect. Dis. 187:2003;287-291.
-
(2003)
J. Infect. Dis.
, vol.187
, pp. 287-291
-
-
Blairon, L.1
Wittebole, X.2
Laterre, P.F.3
-
5
-
-
0032977353
-
Neuroprotection by a caspase inhibitor in acute bacterial meningitis
-
Braun J.S., Novak R., Herzog K.H., Bodner S.M., Cleveland J.L., Tuomanen E.I. Neuroprotection by a caspase inhibitor in acute bacterial meningitis. Nat. Med. 5:1999;298-302.
-
(1999)
Nat. Med.
, vol.5
, pp. 298-302
-
-
Braun, J.S.1
Novak, R.2
Herzog, K.H.3
Bodner, S.M.4
Cleveland, J.L.5
Tuomanen, E.I.6
-
6
-
-
0030794066
-
Coexistence of CD14-dependent and independent pathways for stimulation of human monocytes by gram-positive bacteria
-
Cauwels A., Wan E., Leismann M., Tuomanen E. Coexistence of CD14-dependent and independent pathways for stimulation of human monocytes by gram-positive bacteria. Infect. Immun. 65:1997;3255-3260.
-
(1997)
Infect. Immun.
, vol.65
, pp. 3255-3260
-
-
Cauwels, A.1
Wan, E.2
Leismann, M.3
Tuomanen, E.4
-
7
-
-
0029165459
-
Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor
-
Cundell D.R., Gerard N.P., Gerard C., Idanpaan-Heikkila I., Tuomanen E.I. Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor. Nature. 377:1995;435-438.
-
(1995)
Nature
, vol.377
, pp. 435-438
-
-
Cundell, D.R.1
Gerard, N.P.2
Gerard, C.3
Idanpaan-Heikkila, I.4
Tuomanen, E.I.5
-
8
-
-
0037079004
-
Dexamethasone in adults with bacterial meningitis
-
de Gans J., van de Beek D. Dexamethasone in adults with bacterial meningitis. N. Engl. J. Med. 347:2002;1549-1556.
-
(2002)
N. Engl. J. Med.
, vol.347
, pp. 1549-1556
-
-
De Gans, J.1
Van de Beek, D.2
-
9
-
-
0034636472
-
Mortality from pneumonia in children in the United States, 1939 through 1996
-
Dowell S.F., Kupronis B.A., Zell E.R., Shay D.K. Mortality from pneumonia in children in the United States, 1939 through 1996. N. Engl. J. Med. 342:2000;1399-1407.
-
(2000)
N. Engl. J. Med.
, vol.342
, pp. 1399-1407
-
-
Dowell, S.F.1
Kupronis, B.A.2
Zell, E.R.3
Shay, D.K.4
-
10
-
-
0034462136
-
Role of MD-2 in TLR2- and TLR4-mediated recognition of Gram-negative and Gram-positive bacteria and activation of chemokine genes
-
Dziarski R., Gupta D. Role of MD-2 in TLR2- and TLR4-mediated recognition of Gram-negative and Gram-positive bacteria and activation of chemokine genes. J. Endotoxin Res. 6:2000;401-405.
-
(2000)
J. Endotoxin Res.
, vol.6
, pp. 401-405
-
-
Dziarski, R.1
Gupta, D.2
-
12
-
-
0033028806
-
Structures in Bacillus subtilis are recognized by CD14 in a lipopolysaccharide binding protein-dependent reaction
-
Fan X., Stelter F., Menzel R., Jack R., Spreitzer I., Hartung T., Schütt C. Structures in Bacillus subtilis are recognized by CD14 in a lipopolysaccharide binding protein-dependent reaction. Infect. Immun. 67:1999;2964-2968.
-
(1999)
Infect. Immun.
, vol.67
, pp. 2964-2968
-
-
Fan, X.1
Stelter, F.2
Menzel, R.3
Jack, R.4
Spreitzer, I.5
Hartung, T.6
Schütt, C.7
-
13
-
-
0034660537
-
A conserved structural motif for lipopolysaccharide recognition by procaryotic and eucaryotic proteins
-
Ferguson A.D., Welte W., Hofmann E., Lindner B., Holst O., Coulton J.W., Diederichs K. A conserved structural motif for lipopolysaccharide recognition by procaryotic and eucaryotic proteins. Struct. Fold. Des. 8:2000;585-592.
-
(2000)
Struct. Fold. Des.
, vol.8
, pp. 585-592
-
-
Ferguson, A.D.1
Welte, W.2
Hofmann, E.3
Lindner, B.4
Holst, O.5
Coulton, J.W.6
Diederichs, K.7
-
14
-
-
0037097521
-
The role of lipopolysaccharide binding protein in resistance to Salmonella infections in mice
-
Fierer J., Swancutt M.A., Heumann D., Golenbock D. The role of lipopolysaccharide binding protein in resistance to Salmonella infections in mice. J. Immunol. 168:2002;6396-6403.
-
(2002)
J. Immunol.
, vol.168
, pp. 6396-6403
-
-
Fierer, J.1
Swancutt, M.A.2
Heumann, D.3
Golenbock, D.4
-
15
-
-
0021322901
-
Production and release of peptidoglycan and wall teichoic acid polymers in pneumococci treated with beta-lactam antibiotics
-
Fischer H., Tomasz A. Production and release of peptidoglycan and wall teichoic acid polymers in pneumococci treated with beta-lactam antibiotics. J. Bacteriol. 157:1984;507-513.
-
(1984)
J. Bacteriol.
, vol.157
, pp. 507-513
-
-
Fischer, H.1
Tomasz, A.2
-
16
-
-
0032825681
-
Cerebral endothelial cells release TNF-α after stimulation with cell walls of Streptococcus pneumoniae and regulate inducible nitric oxide synthase and ICAM-1 expression via autocrine loops
-
Freyer D., Manz R., Ziegenhorn A., Weih M., Angstwurm K., Docke W.D., Meisel A., Schumann R.R., Schonfelder G., Dirnagl U., Weber J.R. Cerebral endothelial cells release TNF-α after stimulation with cell walls of Streptococcus pneumoniae and regulate inducible nitric oxide synthase and ICAM-1 expression via autocrine loops. J. Immunol. 163:1999;4308-4314.
-
(1999)
J. Immunol.
, vol.163
, pp. 4308-4314
-
-
Freyer, D.1
Manz, R.2
Ziegenhorn, A.3
Weih, M.4
Angstwurm, K.5
Docke, W.D.6
Meisel, A.7
Schumann, R.R.8
Schonfelder, G.9
Dirnagl, U.10
Weber, J.R.11
-
17
-
-
0023138275
-
Teichoic acid-containing muropeptides from Streptococcus pneumoniae as substrates for the pneumococcal autolysin
-
Garcia-Bustos J.F., Tomasz A. Teichoic acid-containing muropeptides from Streptococcus pneumoniae as substrates for the pneumococcal autolysin. J. Bacteriol. 169:1987;447-453.
-
(1987)
J. Bacteriol.
, vol.169
, pp. 447-453
-
-
Garcia-Bustos, J.F.1
Tomasz, A.2
-
18
-
-
0025075877
-
A biological price of antibiotic resistance: Major changes in the peptidoglycan structure of penicillin-resistant pneumococci
-
Garcia-Bustos J., Tomasz A. A biological price of antibiotic resistance. major changes in the peptidoglycan structure of penicillin-resistant pneumococci Proc. Natl. Acad. Sci. USA. 87:1990;5415-5419.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 5415-5419
-
-
Garcia-Bustos, J.1
Tomasz, A.2
-
19
-
-
0023656752
-
Structure of the peptide network of pneumococcal peptidoglycan
-
Garcia-Bustos J.F., Chait B.T., Tomasz A. Structure of the peptide network of pneumococcal peptidoglycan. J. Biol. Chem. 262:1987;15400-15405.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 15400-15405
-
-
Garcia-Bustos, J.F.1
Chait, B.T.2
Tomasz, A.3
-
20
-
-
0029005366
-
Characterization of the structural elements in lipid A required for binding of a recombinant fragment of bactericidal/permeability-increasing protein rBPI23
-
Gazzano-Santoro H., Parent J.B., Conlon P.J., Kasler H.G., Tsai C.M., Lill-Elghanian D.A., Hollingsworth R.I. Characterization of the structural elements in lipid A required for binding of a recombinant fragment of bactericidal/permeability-increasing protein rBPI23. Infect. Immun. 63:1995;2201-2205.
-
(1995)
Infect. Immun.
, vol.63
, pp. 2201-2205
-
-
Gazzano-Santoro, H.1
Parent, J.B.2
Conlon, P.J.3
Kasler, H.G.4
Tsai, C.M.5
Lill-Elghanian, D.A.6
Hollingsworth, R.I.7
-
21
-
-
0031473847
-
SWISS-MODEL and the Swiss-PdbViewer: An environment for comparative protein modeling
-
Guex N., Peitsch M.C. SWISS-MODEL and the Swiss-PdbViewer. an environment for comparative protein modeling Electrophoresis. 18:1997;2714-2723.
-
(1997)
Electrophoresis
, vol.18
, pp. 2714-2723
-
-
Guex, N.1
Peitsch, M.C.2
-
22
-
-
0033987173
-
Binding of lipopolysaccharide (LPS) to CHO cells does not correlate with LPS-induced NF-kappaB activation
-
Hamann L., Schumann R.R., Flad H.D., Brade L., Rietschel E.T., Ulmer A.J. Binding of lipopolysaccharide (LPS) to CHO cells does not correlate with LPS-induced NF-kappaB activation. Eur. J. Immunol. 30:2000;211-216.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 211-216
-
-
Hamann, L.1
Schumann, R.R.2
Flad, H.D.3
Brade, L.4
Rietschel, E.T.5
Ulmer, A.J.6
-
23
-
-
0035423442
-
The essential role of lipopolysaccharide-binding protein in protection of mice against a peritoneal Salmonella infection involves the rapid induction of an inflammatory response
-
Heinrich J.M., Bernheiden M., Minigo G., Yang K.K., Schutt C., Mannel D.N., Jack R.S. The essential role of lipopolysaccharide-binding protein in protection of mice against a peritoneal Salmonella infection involves the rapid induction of an inflammatory response. J. Immunol. 167:2001;1624-1628.
-
(2001)
J. Immunol.
, vol.167
, pp. 1624-1628
-
-
Heinrich, J.M.1
Bernheiden, M.2
Minigo, G.3
Yang, K.K.4
Schutt, C.5
Mannel, D.N.6
Jack, R.S.7
-
24
-
-
0036180692
-
Cytokine induction by purified lipoteichoic acids from various bacterial species - Role of LBP, sCD14, CD14 and failure to induce IL-12 and subsequent IFN-gamma release
-
Hermann C., Spreitzer I., Schroder N.W., Morath S., Lehner M.D., Fischer W., Schutt C., Schumann R.R., Hartung T. Cytokine induction by purified lipoteichoic acids from various bacterial species - role of LBP, sCD14, CD14 and failure to induce IL-12 and subsequent IFN-gamma release. Eur. J. Immunol. 32:2002;541-551.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 541-551
-
-
Hermann, C.1
Spreitzer, I.2
Schroder, N.W.3
Morath, S.4
Lehner, M.D.5
Fischer, W.6
Schutt, C.7
Schumann, R.R.8
Hartung, T.9
-
25
-
-
0028285885
-
Gram-positive cell walls stimulate synthesis of tumor necrosis factor alpha and interleukin-6 by human monocytes
-
Heumann D., Barras C., Severin A., Glauser M.P., Tomasz A. Gram-positive cell walls stimulate synthesis of tumor necrosis factor alpha and interleukin-6 by human monocytes. Infect. Immun. 62:1994;2715-2721.
-
(1994)
Infect. Immun.
, vol.62
, pp. 2715-2721
-
-
Heumann, D.1
Barras, C.2
Severin, A.3
Glauser, M.P.4
Tomasz, A.5
-
26
-
-
0036320632
-
Triptans reduce the inflammatory response in bacterial meningitis
-
Hoffmann O., Keilwerth N., Bille M.B., Reuter U., Angstwurm K., Schumann R.R., Dirnagl U., Weber J.R. Triptans reduce the inflammatory response in bacterial meningitis. J. Cereb. Blood Flow Metab. 22:2002;988-996.
-
(2002)
J. Cereb. Blood Flow Metab.
, vol.22
, pp. 988-996
-
-
Hoffmann, O.1
Keilwerth, N.2
Bille, M.B.3
Reuter, U.4
Angstwurm, K.5
Schumann, R.R.6
Dirnagl, U.7
Weber, J.R.8
-
27
-
-
0021211819
-
Binding of C-reactive protein to the pneumococcal capsule or cell wall results in differential localization of C3 and stimulation of phagocytosis
-
Holzer T.J., Edwards K.M., Gewurz H., Mold C. Binding of C-reactive protein to the pneumococcal capsule or cell wall results in differential localization of C3 and stimulation of phagocytosis. J. Immunol. 133:1984;1424-1430.
-
(1984)
J. Immunol.
, vol.133
, pp. 1424-1430
-
-
Holzer, T.J.1
Edwards, K.M.2
Gewurz, H.3
Mold, C.4
-
28
-
-
0037040907
-
The carboxyl-terminal domain of closely related endotoxin-binding proteins determines the target of protein-lipopolysaccharide complexes
-
Iovine N., Eastvold J., Elsbach P., Weiss J.P., Gioannini T.L. The carboxyl-terminal domain of closely related endotoxin-binding proteins determines the target of protein-lipopolysaccharide complexes. J. Biol. Chem. 277:2002;7970-7978.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 7970-7978
-
-
Iovine, N.1
Eastvold, J.2
Elsbach, P.3
Weiss, J.P.4
Gioannini, T.L.5
-
29
-
-
0030685133
-
Lipopolysaccharide-binding protein is required to combat a murine gram-negative bacterial infection
-
Jack R.S., Fan X., Bernheiden M., Rune G., Ehlers M., Weber A., Kirsch G., Mentel R., Furll B., Freudenberg M.et al. Lipopolysaccharide-binding protein is required to combat a murine gram-negative bacterial infection. Nature. 389:1997;742-745.
-
(1997)
Nature
, vol.389
, pp. 742-745
-
-
Jack, R.S.1
Fan, X.2
Bernheiden, M.3
Rune, G.4
Ehlers, M.5
Weber, A.6
Kirsch, G.7
Mentel, R.8
Furll, B.9
Freudenberg, M.10
-
31
-
-
0030588577
-
Effects of site-directed mutagenesis of basic residues (Arg 94, Lys 95, Lys 99) of lipopolysaccharide (LPS)-binding protein on binding and transfer of LPS and subsequent immune cell activation
-
Lamping N., Hoess A., Yu B., Park T.C., Kirschning C.J., Pfeil D., Reuter D., Wright S.D., Herrmann F., Schumann R.R. Effects of site-directed mutagenesis of basic residues (Arg 94, Lys 95, Lys 99) of lipopolysaccharide (LPS)-binding protein on binding and transfer of LPS and subsequent immune cell activation. J. Immunol. 157:1996;4648-4656.
-
(1996)
J. Immunol.
, vol.157
, pp. 4648-4656
-
-
Lamping, N.1
Hoess, A.2
Yu, B.3
Park, T.C.4
Kirschning, C.J.5
Pfeil, D.6
Reuter, D.7
Wright, S.D.8
Herrmann, F.9
Schumann, R.R.10
-
32
-
-
0032523815
-
LPS-binding protein protects mice from septic shock caused by LPS or gram-negative bacteria
-
Lamping N., Dettmer R., Schroder N.W., Pfeil D., Hallatschek W., Burger R., Schumann R.R. LPS-binding protein protects mice from septic shock caused by LPS or gram-negative bacteria. J. Clin. Invest. 101:1998;2065-2071.
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 2065-2071
-
-
Lamping, N.1
Dettmer, R.2
Schroder, N.W.3
Pfeil, D.4
Hallatschek, W.5
Burger, R.6
Schumann, R.R.7
-
33
-
-
0035860732
-
Peptidoglycan recognition proteins: A novel family of four human innate immunity pattern recognition molecules
-
Liu C., Xu Z., Gupta D., Dziarski R. Peptidoglycan recognition proteins. a novel family of four human innate immunity pattern recognition molecules J. Biol. Chem. 276:2001;34686-34694.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 34686-34694
-
-
Liu, C.1
Xu, Z.2
Gupta, D.3
Dziarski, R.4
-
34
-
-
0033617263
-
Digestion of Streptococcus pneumoniae cell walls with its major peptidoglycan hydrolase releases branched stem peptides carrying proinflammatory activity
-
Majcherczyk P.A., Langen H., Heumann D., Fountoulakis M., Glauser M.P., Moreillon P. Digestion of Streptococcus pneumoniae cell walls with its major peptidoglycan hydrolase releases branched stem peptides carrying proinflammatory activity. J. Biol. Chem. 274:1999;12537-12543.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 12537-12543
-
-
Majcherczyk, P.A.1
Langen, H.2
Heumann, D.3
Fountoulakis, M.4
Glauser, M.P.5
Moreillon, P.6
-
35
-
-
0035856990
-
Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein
-
Michel T., Reichhart J.M., Hoffmann J.A., Royet J. Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein. Nature. 414:2001;756-759.
-
(2001)
Nature
, vol.414
, pp. 756-759
-
-
Michel, T.1
Reichhart, J.M.2
Hoffmann, J.A.3
Royet, J.4
-
36
-
-
0036534446
-
Differential effects of p38- and extracellular signal-regulated kinase mitogen-activated protein kinase inhibitors on inducible nitric oxide synthase and tumor necrosis factor production in murine macrophages stimulated with Streptococcus pneumoniae
-
Monier R.M., Orman K.L., Meals E.A., English B.K. Differential effects of p38- and extracellular signal-regulated kinase mitogen-activated protein kinase inhibitors on inducible nitric oxide synthase and tumor necrosis factor production in murine macrophages stimulated with Streptococcus pneumoniae. J. Infect. Dis. 185:2002;921-926.
-
(2002)
J. Infect. Dis.
, vol.185
, pp. 921-926
-
-
Monier, R.M.1
Orman, K.L.2
Meals, E.A.3
English, B.K.4
-
37
-
-
0032754358
-
Relationship between plasma levels of lipopolysaccharide (LPS) and LPS-binding protein in patients with severe sepsis and septic shock
-
Opal S.M., Scannon P.J., Vincent J.L., White M., Carroll S.F., Palardy J.E., Parejo N.A., Pribble J.P., Lemke J.H. Relationship between plasma levels of lipopolysaccharide (LPS) and LPS-binding protein in patients with severe sepsis and septic shock. J. Infect. Dis. 180:1999;1584-1589.
-
(1999)
J. Infect. Dis.
, vol.180
, pp. 1584-1589
-
-
Opal, S.M.1
Scannon, P.J.2
Vincent, J.L.3
White, M.4
Carroll, S.F.5
Palardy, J.E.6
Parejo, N.A.7
Pribble, J.P.8
Lemke, J.H.9
-
38
-
-
0001701294
-
Toll-like receptor-2 mediates Treponema glycolipid and lipoteichoic acid-induced NF-κB translocation
-
Opitz B., Schroder N.W., Spreitzer I., Michelsen K.S., Kirschning C.J., Hallatschek W., Zahringer U., Hartung T., Gobel U.B., Schumann R.R. Toll-like receptor-2 mediates Treponema glycolipid and lipoteichoic acid-induced NF-κB translocation. J. Biol. Chem. 276:2001;22041-22047.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 22041-22047
-
-
Opitz, B.1
Schroder, N.W.2
Spreitzer, I.3
Michelsen, K.S.4
Kirschning, C.J.5
Hallatschek, W.6
Zahringer, U.7
Hartung, T.8
Gobel, U.B.9
Schumann, R.R.10
-
40
-
-
0032527622
-
Pneumococcal trafficking across the blood-brain barrier. Molecular analysis of a novel bidirectional pathway
-
Ring A., Weiser J.N., Tuomanen E.I. Pneumococcal trafficking across the blood-brain barrier. Molecular analysis of a novel bidirectional pathway. J. Clin. Invest. 102:1998;347-360.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 347-360
-
-
Ring, A.1
Weiser, J.N.2
Tuomanen, E.I.3
-
41
-
-
0030587127
-
Mycobacterial lipoarabinomannan recognition requires a receptor that shares components of the endotoxin signaling system
-
Savedra R. Jr., Delude R.L., Ingalls R.R., Fenton M.J., Golenbock D.T. Mycobacterial lipoarabinomannan recognition requires a receptor that shares components of the endotoxin signaling system. J. Immunol. 157:1996;2549-2554.
-
(1996)
J. Immunol.
, vol.157
, pp. 2549-2554
-
-
Savedra R., Jr.1
Delude, R.L.2
Ingalls, R.R.3
Fenton, M.J.4
Golenbock, D.T.5
-
42
-
-
0032719350
-
Clinical outcome in pneumococcal meningitis correlates with CSF lipoteichoic acid concentrations
-
Schneider O., Michel U., Zysk G., Dubuis O., Nau R. Clinical outcome in pneumococcal meningitis correlates with CSF lipoteichoic acid concentrations. Neurology. 53:1999;1584-1587.
-
(1999)
Neurology
, vol.53
, pp. 1584-1587
-
-
Schneider, O.1
Michel, U.2
Zysk, G.3
Dubuis, O.4
Nau, R.5
-
43
-
-
0034283666
-
Involvement of lipopolysaccharide binding protein, CD14, and Toll-like receptors in the initiation of innate immune responses by Treponema glycolipids
-
Schroder N.W., Opitz B., Lamping N., Michelsen K.S., Zahringer U., Gobel U.B., Schumann R.R. Involvement of lipopolysaccharide binding protein, CD14, and Toll-like receptors in the initiation of innate immune responses by Treponema glycolipids. J. Immunol. 165:2000;2683-2693.
-
(2000)
J. Immunol.
, vol.165
, pp. 2683-2693
-
-
Schroder, N.W.1
Opitz, B.2
Lamping, N.3
Michelsen, K.S.4
Zahringer, U.5
Gobel, U.B.6
Schumann, R.R.7
-
44
-
-
0038182550
-
Lipoteichoic acid (LTA) of S. pneumoniae and S. aureus activates immune cells via toll-like receptor (TLR)-2, LPS binding protein (LBP) and CD14 while TLR-4 and MD-2 are not involved
-
Schroder N.W., Morath S., Alexander C., Hamann L., Hartung T., Zahringer U., Gobel U.B., Weber J.R., Schumann R.R. Lipoteichoic acid (LTA) of S. pneumoniae and S. aureus activates immune cells via toll-like receptor (TLR)-2, LPS binding protein (LBP) and CD14 while TLR-4 and MD-2 are not involved. J. Biol. Chem. 278:2003;15587-15594.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 15587-15594
-
-
Schroder, N.W.1
Morath, S.2
Alexander, C.3
Hamann, L.4
Hartung, T.5
Zahringer, U.6
Gobel, U.B.7
Weber, J.R.8
Schumann, R.R.9
-
45
-
-
0030779037
-
Bacterial meningitis in the United States in 1995
-
Schuchat A., Robinson K., Wenger J.D., Harrison L.H., Farley M., Reingold A.L., Lefkowitz L., Perkins B.A. Bacterial meningitis in the United States in 1995. Active Surveillance Team. N. Engl. J. Med. 337:1997;970-976.
-
(1997)
Active Surveillance Team. N. Engl. J. Med.
, vol.337
, pp. 970-976
-
-
Schuchat, A.1
Robinson, K.2
Wenger, J.D.3
Harrison, L.H.4
Farley, M.5
Reingold, A.L.6
Lefkowitz, L.7
Perkins, B.A.8
-
46
-
-
0025107568
-
Structure and function of lipopolysaccharide binding protein
-
Schumann R.R., Leong S.R., Flaggs G.W., Gray P.W., Wright S.D., Mathison J.C., Tobias P.S., Ulevitch R.J. Structure and function of lipopolysaccharide binding protein. Science. 249:1990;1429-1431.
-
(1990)
Science
, vol.249
, pp. 1429-1431
-
-
Schumann, R.R.1
Leong, S.R.2
Flaggs, G.W.3
Gray, P.W.4
Wright, S.D.5
Mathison, J.C.6
Tobias, P.S.7
Ulevitch, R.J.8
-
47
-
-
0031298184
-
Interchangeable endotoxin-binding domains in proteins with opposite lipopolysaccharide-dependent activities
-
Schumann R.R., Lamping N., Hoess A. Interchangeable endotoxin-binding domains in proteins with opposite lipopolysaccharide-dependent activities. J. Immunol. 159:1997;5599-5605.
-
(1997)
J. Immunol.
, vol.159
, pp. 5599-5605
-
-
Schumann, R.R.1
Lamping, N.2
Hoess, A.3
-
48
-
-
0032032651
-
Lipopolysaccharide and pneumococcal cell wall components activate the mitogen activated protein kinases (MAPK) erk-1, erk-2, and p 38 in astrocytes
-
Schumann R.R., Pfeil D., Bürger W., Lamping N., Kirschning C.J., Goebel U., Weber J.R. Lipopolysaccharide and pneumococcal cell wall components activate the mitogen activated protein kinases (MAPK) erk-1, erk-2, and p 38 in astrocytes. Glia. 22:1998;295-305.
-
(1998)
Glia
, vol.22
, pp. 295-305
-
-
Schumann, R.R.1
Pfeil, D.2
Bürger, W.3
Lamping, N.4
Kirschning, C.J.5
Goebel, U.6
Weber, J.R.7
-
49
-
-
0030025463
-
Naturally occurring peptidoglycan variants of Streptococcus pneumoniae
-
Severin A., Tomasz A. Naturally occurring peptidoglycan variants of Streptococcus pneumoniae. J. Bacteriol. 178:1996;168-174.
-
(1996)
J. Bacteriol.
, vol.178
, pp. 168-174
-
-
Severin, A.1
Tomasz, A.2
-
50
-
-
0029886855
-
Pneumococcal cell wall activates NF-kappa B in human monocytes: Aspects distinct from endotoxin
-
Spellerberg B., Rosenow C., Sha W., Tuomanen E.I. Pneumococcal cell wall activates NF-kappa B in human monocytes. aspects distinct from endotoxin Microb. Pathog. 20:1996;309-317.
-
(1996)
Microb. Pathog.
, vol.20
, pp. 309-317
-
-
Spellerberg, B.1
Rosenow, C.2
Sha, W.3
Tuomanen, E.I.4
-
51
-
-
0029893116
-
Cytokine-induced meningitis is dramatically attenuated in mice deficient in endothelial selectins
-
Tang T., Frenette P.S., Hynes R.O., Wagner D.D., Mayadas T.N. Cytokine-induced meningitis is dramatically attenuated in mice deficient in endothelial selectins. J. Clin. Invest. 97:1996;2485-2490.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 2485-2490
-
-
Tang, T.1
Frenette, P.S.2
Hynes, R.O.3
Wagner, D.D.4
Mayadas, T.N.5
-
52
-
-
0024316023
-
Identification of a lipid A binding site in the acute phase reactant lipopolysaccharide binding protein
-
Tobias P.S., Soldau K., Ulevitch R.J. Identification of a lipid A binding site in the acute phase reactant lipopolysaccharide binding protein. J. Biol. Chem. 264:1989;10867-10871.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 10867-10871
-
-
Tobias, P.S.1
Soldau, K.2
Ulevitch, R.J.3
-
53
-
-
0028924539
-
Lipopolysaccharide binding protein-mediated complexation of lipopolysaccharide with soluble CD14
-
Tobias P.S., Soldau K., Gegner J.A., Mintz D., Ulevitch R.J. Lipopolysaccharide binding protein-mediated complexation of lipopolysaccharide with soluble CD14. J. Biol. Chem. 270:1995;10482-10488.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 10482-10488
-
-
Tobias, P.S.1
Soldau, K.2
Gegner, J.A.3
Mintz, D.4
Ulevitch, R.J.5
-
54
-
-
0019542603
-
Surface components of Streptococcus pneumoniae
-
Tomasz A. Surface components of Streptococcus pneumoniae. Rev. Infect. Dis. 3:1981;190-211.
-
(1981)
Rev. Infect. Dis.
, vol.3
, pp. 190-211
-
-
Tomasz, A.1
-
56
-
-
0022001683
-
The induction of meningeal inflammation by components of the pneumococcal cell wall
-
Tuomanen E., Liu H., Hengstler B., Zak O., Tomasz A. The induction of meningeal inflammation by components of the pneumococcal cell wall. J. Infect. Dis. 151:1985;859-868.
-
(1985)
J. Infect. Dis.
, vol.151
, pp. 859-868
-
-
Tuomanen, E.1
Liu, H.2
Hengstler, B.3
Zak, O.4
Tomasz, A.5
-
57
-
-
0023180703
-
Nonsteroidal anti-inflammatory agents in the therapy for experimental pneumococcal meningitis
-
Tuomanen E., Hengstler B., Rich R., Bray M.A., Zak O., Tomasz A. Nonsteroidal anti-inflammatory agents in the therapy for experimental pneumococcal meningitis. J. Infect. Dis. 155:1987;985-990.
-
(1987)
J. Infect. Dis.
, vol.155
, pp. 985-990
-
-
Tuomanen, E.1
Hengstler, B.2
Rich, R.3
Bray, M.A.4
Zak, O.5
Tomasz, A.6
-
58
-
-
0024421227
-
Reduction of inflammation, tissue damage, and mortality in bacterial meningitis in rabbits treated with monoclonal antibodies against adhesion-promoting receptors of leukocytes
-
Tuomanen E.I., Saukkonen K., Sande S., Cioffe C., Wright S.D. Reduction of inflammation, tissue damage, and mortality in bacterial meningitis in rabbits treated with monoclonal antibodies against adhesion-promoting receptors of leukocytes. J. Exp. Med. 170:1989;959-969.
-
(1989)
J. Exp. Med.
, vol.170
, pp. 959-969
-
-
Tuomanen, E.I.1
Saukkonen, K.2
Sande, S.3
Cioffe, C.4
Wright, S.D.5
-
59
-
-
0028965644
-
Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin
-
Ulevitch R.J., Tobias P.S. Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu. Rev. Immunol. 13:1995;437-457.
-
(1995)
Annu. Rev. Immunol.
, vol.13
, pp. 437-457
-
-
Ulevitch, R.J.1
Tobias, P.S.2
-
60
-
-
0034668015
-
Lipopolysaccharide-binding protein is vectorially secreted and transported by cultured intestinal epithelial cells and is present in the intestinal mucus of mice
-
Vreugdenhil A.C., Snoek A.M., Greve J.W., Buurman W.A. Lipopolysaccharide-binding protein is vectorially secreted and transported by cultured intestinal epithelial cells and is present in the intestinal mucus of mice. J. Immunol. 165:2000;4561-4566.
-
(2000)
J. Immunol.
, vol.165
, pp. 4561-4566
-
-
Vreugdenhil, A.C.1
Snoek, A.M.2
Greve, J.W.3
Buurman, W.A.4
-
61
-
-
0028788966
-
Anti ICAM-1 (CD54) monoclonal antibody reduces inflammatory changes in experimental bacterial meningitis
-
Weber J.R., Angstwurm K., Bürger W., Einhäupl K.M., Dirnagl U. Anti ICAM-1 (CD54) monoclonal antibody reduces inflammatory changes in experimental bacterial meningitis. J. Neuroimmunol. 63:1995;63-68.
-
(1995)
J. Neuroimmunol.
, vol.63
, pp. 63-68
-
-
Weber, J.R.1
Angstwurm, K.2
Bürger, W.3
Einhäupl, K.M.4
Dirnagl, U.5
-
62
-
-
0030778068
-
Heparin inhibits leukocyte rolling in pial vessels and attenuates inflammatory changes in a rat model of experimental bacterial meningitis
-
Weber J.R., Angstwurm K., Rosenkranz T., Lindauer U., Freyer D., Burger W., Busch C., Einhaupl K.M., Dirnagl U. Heparin inhibits leukocyte rolling in pial vessels and attenuates inflammatory changes in a rat model of experimental bacterial meningitis. J. Cereb. Blood Flow Metab. 17:1997;1221-1229.
-
(1997)
J. Cereb. Blood Flow Metab.
, vol.17
, pp. 1221-1229
-
-
Weber, J.R.1
Angstwurm, K.2
Rosenkranz, T.3
Lindauer, U.4
Freyer, D.5
Burger, W.6
Busch, C.7
Einhaupl, K.M.8
Dirnagl, U.9
-
63
-
-
0018134831
-
Activation of the alternative complement pathway by pneumococcal cell wall teichoic acid
-
Winkelstein J.A., Tomasz A. Activation of the alternative complement pathway by pneumococcal cell wall teichoic acid. J. Immunol. 120:1978;174-178.
-
(1978)
J. Immunol.
, vol.120
, pp. 174-178
-
-
Winkelstein, J.A.1
Tomasz, A.2
-
64
-
-
0031440937
-
Targeted deletion of the lipopolysaccharide (LPS)-binding protein gene leads to profound suppression of LPS responses ex vivo, whereas in vivo responses remain intact
-
Wurfel M.M., Monks B.G., Ingalls R.R., Dedrick R.L., Delude R., Zhou D., Lamping N., Schumann R.R., Thieringer R., Fenton M.J.et al. Targeted deletion of the lipopolysaccharide (LPS)-binding protein gene leads to profound suppression of LPS responses ex vivo, whereas in vivo responses remain intact. J. Exp. Med. 186:1997;2051-2056.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 2051-2056
-
-
Wurfel, M.M.1
Monks, B.G.2
Ingalls, R.R.3
Dedrick, R.L.4
Delude, R.5
Zhou, D.6
Lamping, N.7
Schumann, R.R.8
Thieringer, R.9
Fenton, M.J.10
-
65
-
-
0037108521
-
Neutrophil influx in response to a peritoneal infection with Salmonella is delayed in lipopolysaccharide-binding protein or CD14-deficient mice
-
Yang K.K., Dorner B.G., Merkel U., Ryffel B., Schutt C., Golenbock D., Freeman M.W., Jack R.S. Neutrophil influx in response to a peritoneal infection with Salmonella is delayed in lipopolysaccharide-binding protein or CD14-deficient mice. J. Immunol. 169:2002;4475-4480.
-
(2002)
J. Immunol.
, vol.169
, pp. 4475-4480
-
-
Yang, K.K.1
Dorner, B.G.2
Merkel, U.3
Ryffel, B.4
Schutt, C.5
Golenbock, D.6
Freeman, M.W.7
Jack, R.S.8
-
66
-
-
0033168728
-
Cutting edge: Recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2
-
Yoshimura A., Lien E., Ingalls R.R., Tuomanen E., Dziarski R., Golenbock D. Cutting edge. recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2 J. Immunol. 163:1999;1-5.
-
(1999)
J. Immunol.
, vol.163
, pp. 1-5
-
-
Yoshimura, A.1
Lien, E.2
Ingalls, R.R.3
Tuomanen, E.4
Dziarski, R.5
Golenbock, D.6
-
68
-
-
0035895085
-
High concentrations of lipopolysaccharide-binding protein in serum of patients with severe sepsis or septic shock inhibit the lipopolysaccharide response in human monocytes
-
Zweigner J., Gramm H.J., Singer O.C., Wegscheider K., Schumann R.R. High concentrations of lipopolysaccharide-binding protein in serum of patients with severe sepsis or septic shock inhibit the lipopolysaccharide response in human monocytes. Blood. 98:2001;3800-3808.
-
(2001)
Blood
, vol.98
, pp. 3800-3808
-
-
Zweigner, J.1
Gramm, H.J.2
Singer, O.C.3
Wegscheider, K.4
Schumann, R.R.5
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