Pneumococcal trafficking across the blood-brain barrier molecular analysis of a novel bidirectional pathway

Journal of Clinical Investigation

Volumn 102, Issue 2, 1998, Pages 347-360

  Ring, Axel ^a   Weiser, Jeffrey N ^b   Tuomanen, Elaine I ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Adhesins; Endocytosis; Endothelial cells; Streptococcus pneumoniae; Transmigration

Indexed keywords

THROMBOCYTE ACTIVATING FACTOR RECEPTOR;

ANIMAL CELL; ARTICLE; BACTERIAL TRANSLOCATION; BACTERIUM ADHERENCE; BLOOD BRAIN BARRIER; BRAIN BLOOD VESSEL; CELL IMMORTALIZATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOCOCCUS PNEUMONIAE; TRANSCYTOSIS; VASCULAR ENDOTHELIUM;

EID: 0032527622     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI2406     Document Type: Article

References (39)

1. Stins, M.F., N.V. Prasadanio, L. Ibric, C.A. Wass, P. Luckett, and K.S. Kim. 1994. Binding characteristics of S fimbriated Escherichia coli to isolated brain microvascular endothelial cells. Am. J. Pathol. 145:1228-1236.
2. Huang, S.H., C.A. Wass, Q. Fu, N.V. Prasadarao, M.F. Stins, and K.S. Kim. 1995. Escherichia coli invasion of brain microvascular endothelial cells in vitro and in vivo: molecular cloning and characterization of invasion gene ibe10. Infect. Immun. 63:4470-4475.
3. Prasadarao, N.V., C. Wass, J.N. Weiser, M.F. Stins, S. Huang, and K.S. Kim. 1996. Outer membrane protein A of Escherichia coli contributes to invasion of brain microvascular endothelial cells. Infect. Immun. 64:146-153.
4. Krivan, H.C., D.D. Roberts, and V. Ginsburg. 1988. Many pulmonary pathogenic bacteria bind specifically to the carbohydrate sequence GalNAc β1-4 Gal found in some glycolipids. Proc. Natl. Acad. Sci. USA. 85:6157-6161.
5. Andersson, B., B. Eriksson, E. Falsen, A. Fogh, L. Hanson, H. Nylen, H. Peterson, and C. Svanborg-Eden. 1981. Adhesion of Streptococcus pneumoniae to human pharyngeal cells in vitro. Infect. Immun. 32:311-317.
6. Cundell, D.R., N.P. Gerard, C. Gerard, I. Idänpään-Heikkilä. and E.I. Tuomanen. 1995. Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor. Nature. 377:435-438.
7. Cundell, D.R., J.N. Weiser, J. Shen, A. Young, and E.I. Tuomanen. 1995. Relationship between colonial morphology and adherence of Streptococcus pneumoniae. Infect. Immun. 63:757-761.
8. Weiser, J.N., R. Austrian, P.K. Sreenivasan, and H.R. Masure. 1994. Phase variation in pneumococcal opacity: relationship between colonial morphology and nasopharyngeal colonization. Infect. Immun. 62:2582-2589.
9. Kim, J.O., and J.N. Weiser. 1998. Association of intrastrain phase variation in quantity of capsular polysaccharide and teichoic acid with the virulence of Streptococcus pneumoniae. J. Infect. Dis. 177:368-377.
10. Weiser, J.N., Z. Markiewicz, E.I. Tuomanen, and J.H. Wani. 1996. Relationship between phase variation in colony morphology, intrastrain variation in cell wall physiology, and nasopharyngeal colonization by Streptococcus pneumoniae. Infect. Immun. 64:2240-2245.
11. Rosenow, C., P. Ryan, J.N. Weiser, S. Johnson, P. Fontan, A. Ortqvist, and H.R. Masure. 1997. Contribution of novel choline-binding proteins to adherence, colonization and immunogenicity of Streptococcus pneumoniae. Mol. Microbiol. 25:819-829.
12. Morrison, D.A., M.C. Trombe, M.K. Hayden, G.A. Waszak, and J.D. Chen. 1984. Isolation of transformation-deficient Streptococcus pneumoniae mutants defective in control of competence, using insertion-duplication mutagenesis with the erythromycin resistance determinant of pAM beta 1. J. Bacteriol. 159:870-876.
13. Lacks, S., and R.D. Hotchkiss. 1960. A study of the genetic material determining an enzyme activity in pneumococcus. Biochem. Biophys. Acta. 39: 508-517.
14. Juillerat-Jeanneret, L., A. Aguzzi, O.D. Wiestler, P. Darekar, and C. Janzer. 1992. Dexamethasone selectively regulates the activity of enzymatic markers of cerebral endothelial cell lines. In Vitro Cell. Dev. Biol. 28A:537-543.
15. Aguzzi, A., P. Kleihues, K. Heckl, and O.D. Wiestler. 1991. Cell-type specific tumor induction in neural transplants by retrovirus-mediated oncogene transfer. Oncogene. 6:113-118.
16. Nizet, V., K.S. Kim, M. Stins, M. Jonas, E.Y. Chi, D. Nguyen, and C.E. Rubens. 1997. Invasion of brain microvascular endothelial cells by group B streptococci. Infect. Immun. 65:5074-5081.
17. Tang, P., M. Foubister, M.G. Pucciarelli, and B.B. Finlay. 1993. Methods to study bacterial invasion. J. Microbiol. Methods. 18:227-240.
18. Isberg, R.R., and S. Falkow. 1985. A single genetic locus encoded by Yersinia pseudotuberculosis permits invasion of cultured animal cells by Escherichia coli K-12. Nature. 317:262-264.
19. Talbot, U.M., A.W. Paton, and J.C. Paton. 1996. Uptake of Streptococcus pneumoniae by respiratory epithelial cells. Infect. Immun. 64:3772-3777.
20. Pitrak, D.L., H.C. Tsai, K.M. McMullane, S.H. Sutton, and P. Stevens. 1996. Accelerated neutrophil apoptosis in the acquired immunodeficiency syndrome. J. Clin. Invest. 98:2714-2719.
21. Ponpipom, M.M., S. Hwang, T.W. Doebber, J.J. Acton, A.W. Alberts, T. Biftu, D.R. Brooker, R.L. Bugianesi, J.C. Chabala, N.L. Gamble, et al. 1988. (+/-)-trans-2-(3-Methoxy-5-methylsulfonyl-4-propoxyphenyl)-5-(3,4,5- trimethoxyphenyl)tetrahydrofuran (L-659,989), a novel, potent PAF receptor antagonist. Biochem. Biophys. Res. Commun. 150:1213-1220.
22. Bito, H., Z. Honda, M. Nakamura, and T. Shimizu. 1994. Cloning, expression and tissue distribution of rat platelet-activating-factor-receptor cDNA. Eur. J. Biochem. 221:211-218.
23. Geelen, S., C. Bhattacharrya, and E. Tuomanen. 1993. The cell wall mediates pneumococcal attachment to and cytopathology in human endothelial cells. Infect. Immun. 61:1538-1543.
24. Quagliarello, V.J., W.J. Long, and W.M. Scheld. 1986. Morphologic alterations of the blood-brain barrier with experimental meningitis in the rat. Temporal sequence and role of encapsulation. J. Clin. Invest. 77:11184-1095.
25. Pucciarelli, M.G., and B.B. Finlay. 1994. Polarized epithelial monolayers: model systems to study bacterial interactions with host epithelial cells. Methods Enzymol. 236:438-447.
26. Ring, A., and E. Tuomanen. 1997. Targeting bacteria to the central nervous system. In In Defense of the Brain. P.K. Peterson and J.S. Remington, editors. Blackwell Science, Malden, MA. 90-106.
27. Hulse, M.L., S. Smith, E.Y. Chi, A. Pham, and C.E. Rubens. 1993. Effect of type III group B streptococcal capsular polysaccharide on invasion of respiratory epithelial cells. Infect. Immun. 61:4835-4841.
28. Tuomanen, E.I. 1997. The biology of pneumococcal infection. Ped. Res. 42:253-258.
29. Gibson, R.L., M.K. Lee, C. Soderland, E.Y. Chi, and C.E. Rubens. 1993. Group B streptococci invade endothelial cells: type III capsular polysaccharide attenuates invasion. Infect. Immun. 61:478-485.
30. Lamont, R.J., A. Chan, C.M. Belton, K.T. Izutsu, D. Vasel, and A. Weinberg. 1995. Porphyromonas gingivalis invasion of gingival epithelial cells. Infect. Immun. 63:3878-3885.
31. Vann, J.M., and R.A. Proctor. 1988. Cytotoxic effects of ingested Staphylococcus aureus on bovine endothelial cells: role of S. aureus alpha-hemolysin. Microbial Pathogenesis. 4:443-453.
32. Bielecki, J., P. Youngman, P. Connelly, and D.A. Portnoy. 1990. Bacillus subtilis expressing a haemolysin gene from Listeria monocytogenes can grow in mammalian cells. Nature. 345:175-176.
33. Birkness, K.A., B.L. Swisher, E.H. White, E.G. Long, E.P. Ewing, and F.D. Quinn. 1995. A tissue culture bilayer model to study the passage of Neisseria meningitidis. Infect. Immun. 63:402-409.
34. Bito, H., Z. Honda, M. Nakamura, and T. Shimizu. 1994. Cloning, expression and tissue distribution of rat platelet-activating-factor-receptor cDNA. Eur. J. Biochem. 221:211-218.
35. Gerard, N.P., and C. Gerard. 1994. Receptor-dependent internalization of platelet-activating factor. J. Immunol. 152:793-800.
36. Pagano, R., and R.G. Sleight. 1984. Defining lipid transport pathways in animal cells. Science. 229:1051-1057.
37. Cabellos, C., D.E. MacIntyre, M. Forrest, M. Burroughs, S. Prasad, and E. Tuomanen. 1992. Differing roles for platelet-activating factor during inflammation of the lung and subarachnoid space. The special case of Streptococcus pneumoniae. J. Clin. Invest. 90:612-618.
38. 3H]paf-acether from, and inhibits its binding to intact human platelets. Eur. J. Pharmacol. 142: 331-341.
39. Spellerberg, B., S. Prasad, C. Cabellos, M. Burroughs, P. Cahill, and E. Tuomanen. 1995. Penetration of the blood-brain barrier enhancement of drug delivery and imaging by bacterial glycopeptides. J. Exp. Med. 182:1037-1043.