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Volumn 101, Issue 10, 1998, Pages 2065-2071

LPS-binding protein protects mice from septic shock caused by LPS or gram-negative bacteria

Author keywords

Antagonist and inhibitors; Gram negative bacterial infection; Lipopolysaccharides; Macrophage activation; Septic shock therapy

Indexed keywords

ALANINE AMINOTRANSFERASE; BACTERIUM LIPOPOLYSACCHARIDE; BINDING PROTEIN; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GALACTOSAMINE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE BINDING PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 0032523815     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI2338     Document Type: Article
Times cited : (298)

References (51)
  • 2
    • 0028965644 scopus 로고
    • Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin
    • Ulevitch, R.J., and P.S. Tobias. 1995. Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu. Rev. Immunol. 13:437-457.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 437-457
    • Ulevitch, R.J.1    Tobias, P.S.2
  • 5
    • 0027920980 scopus 로고
    • Pathogenic mechanisms of septic shock
    • Parillo, J.E. 1993. Pathogenic mechanisms of septic shock. N. Engl. J. Med. 328:1471-1477.
    • (1993) N. Engl. J. Med. , vol.328 , pp. 1471-1477
    • Parillo, J.E.1
  • 7
    • 0023079312 scopus 로고
    • Endotoxin and disease mechanisms
    • Morrison, D.C., and J.L. Ryan. 1987. Endotoxin and disease mechanisms. Annu. Rev. Med. 38:417-432.
    • (1987) Annu. Rev. Med. , vol.38 , pp. 417-432
    • Morrison, D.C.1    Ryan, J.L.2
  • 8
    • 0025285857 scopus 로고
    • Biochemistry of endotoxins
    • Raetz, C.R.H. 1990. Biochemistry of endotoxins. Annu. Rev. Biochem. 59:129-170.
    • (1990) Annu. Rev. Biochem. , vol.59 , pp. 129-170
    • Raetz, C.R.H.1
  • 9
    • 0026653049 scopus 로고
    • Lipopolysaccharide antagonists
    • Lynn, W.A., and D.T. Golenbock. 1992. Lipopolysaccharide antagonists. Immunol. Today. 13:271-276.
    • (1992) Immunol. Today. , vol.13 , pp. 271-276
    • Lynn, W.A.1    Golenbock, D.T.2
  • 11
    • 0025039336 scopus 로고
    • The process of microbial translocation
    • Alexander, J.W., S.T. Boyce, and J.K. Roche. 1990. The process of microbial translocation. Ann. Surg. 212:496-510.
    • (1990) Ann. Surg. , vol.212 , pp. 496-510
    • Alexander, J.W.1    Boyce, S.T.2    Roche, J.K.3
  • 12
    • 0022462376 scopus 로고
    • Isolation of a lipopolysaccharide-binding acute phase reactant from rabbit serum
    • Tobias, P.S., K. Soldau, and R.J. Ulevitch. 1986. Isolation of a lipopolysaccharide-binding acute phase reactant from rabbit serum. J. Exp. Med. 164:777-793.
    • (1986) J. Exp. Med. , vol.164 , pp. 777-793
    • Tobias, P.S.1    Soldau, K.2    Ulevitch, R.J.3
  • 13
    • 0030588577 scopus 로고    scopus 로고
    • Effects of site directed mutagenesis of basic residues (Arg 94, Lys 95, Lys 99) of lipopolysaccharide (LPS) binding protein on binding and transfer of LPS and subsequent immune cell activation
    • Lamping, N., A. Hoess, B. Yu, T.C. Park, C.J. Kirsehning, D. Pfeil, D. Reuter, S.D. Wright, F. Herrmann, and R.R. Schumann. 1996. Effects of site directed mutagenesis of basic residues (Arg 94, Lys 95, Lys 99) of lipopolysaccharide (LPS) binding protein on binding and transfer of LPS and subsequent immune cell activation. J. Immunol. 157:4648-4656.
    • (1996) J. Immunol. , vol.157 , pp. 4648-4656
    • Lamping, N.1    Hoess, A.2    Yu, B.3    Park, T.C.4    Kirsehning, C.J.5    Pfeil, D.6    Reuter, D.7    Wright, S.D.8    Herrmann, F.9    Schumann, R.R.10
  • 14
    • 0025166114 scopus 로고
    • CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein
    • Wright, S.D., R.A. Ramos, P.S. Tobias, R.J. Ulevitch, and J.C. Mathison. 1990. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science. 249:1431-1433.
    • (1990) Science , vol.249 , pp. 1431-1433
    • Wright, S.D.1    Ramos, R.A.2    Tobias, P.S.3    Ulevitch, R.J.4    Mathison, J.C.5
  • 16
    • 0028924539 scopus 로고
    • Lipopolysaccharide binding protein-mediated complexation of lipopolysaccharide with soluble CD14
    • Tobias, P.S., K. Soldau, J.A. Gegner, D. Mintz, and R.J. Ulevitch. 1995. Lipopolysaccharide binding protein-mediated complexation of lipopolysaccharide with soluble CD14. J. Biol. Chem. 270:10482-10488.
    • (1995) J. Biol. Chem. , vol.270 , pp. 10482-10488
    • Tobias, P.S.1    Soldau, K.2    Gegner, J.A.3    Mintz, D.4    Ulevitch, R.J.5
  • 17
    • 0030064009 scopus 로고    scopus 로고
    • Catalytic properties of lipopolysaccharide (LPS) binding protein (LBP). Transfer of LPS to soluble CD14
    • Yu, B., and S.D. Wright. 1996. Catalytic properties of lipopolysaccharide (LPS) binding protein (LBP). Transfer of LPS to soluble CD14. J. Biol. Chem. 271:4100-4105.
    • (1996) J. Biol. Chem. , vol.271 , pp. 4100-4105
    • Yu, B.1    Wright, S.D.2
  • 18
    • 0027982115 scopus 로고
    • Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS
    • Wurfel, M.M., S.T. Kunitake, H. Lichenstein, J.P. Kane, and S.D. Wright. 1994. Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS. J. Exp. Med. 180:1025-1035.
    • (1994) J. Exp. Med. , vol.180 , pp. 1025-1035
    • Wurfel, M.M.1    Kunitake, S.T.2    Lichenstein, H.3    Kane, J.P.4    Wright, S.D.5
  • 20
    • 0026740630 scopus 로고
    • Plasma lipopolysaccharide (LPS)-binding protein. A key component in macrophage recognition of gram-negative LPS
    • Mathison, J.C., P.S. Tobias, E. Wolfson, and R.J. Ulevitch. 1992. Plasma lipopolysaccharide (LPS)-binding protein. A key component in macrophage recognition of gram-negative LPS. J. Immunol. 149:200-206.
    • (1992) J. Immunol. , vol.149 , pp. 200-206
    • Mathison, J.C.1    Tobias, P.S.2    Wolfson, E.3    Ulevitch, R.J.4
  • 21
    • 0028144711 scopus 로고
    • Changes in polymorphonuclear leukocyte surface and plasma bactericidal/permeability-increasing protein and plasma lipopolysaccharide binding protein during endotoxemia or sepsis
    • Calvano, S.E., W.A. Thompson, M.N. Marra, S.M. Coyle, H.F. de Riesthal, R.K. Trousdale, P.S. Barie, R.W. Scott, L.L. Moldawer, and S.F. Lowry. 1994. Changes in polymorphonuclear leukocyte surface and plasma bactericidal/permeability-increasing protein and plasma lipopolysaccharide binding protein during endotoxemia or sepsis. Arch. Surg. 129:220-226.
    • (1994) Arch. Surg. , vol.129 , pp. 220-226
    • Calvano, S.E.1    Thompson, W.A.2    Marra, M.N.3    Coyle, S.M.4    De Riesthal, H.F.5    Trousdale, R.K.6    Barie, P.S.7    Scott, R.W.8    Moldawer, L.L.9    Lowry, S.F.10
  • 22
    • 0028110048 scopus 로고
    • Lipopolysaccharide (LPS)-binding protein in human serum determines the tumor necrosis factor response of monocytes to LPS
    • Gallay, P., C. Barras, P.S. Tobias, T. Calandra, M.P. Glauser, and D. Heumann. 1994. Lipopolysaccharide (LPS)-binding protein in human serum determines the tumor necrosis factor response of monocytes to LPS. J. Infect. Dis. 170:1319-1322.
    • (1994) J. Infect. Dis. , vol.170 , pp. 1319-1322
    • Gallay, P.1    Barras, C.2    Tobias, P.S.3    Calandra, T.4    Glauser, M.P.5    Heumann, D.6
  • 24
    • 0029952277 scopus 로고    scopus 로고
    • The lipopolysaccharide-binding protein is a secretory class 1 acute-phase protein whose gene is transcriptionally activated by APRF/STAT-3 and other cytokine-inducible nuclear proteins
    • Schumann, R.R., C.J. Kirschning, A. Unbehaun, H. Aherle, H.-P. Knopf, N. Lamping, R.J. Ulevitch, and F. Herrmann. 1996. The lipopolysaccharide-binding protein is a secretory class 1 acute-phase protein whose gene is transcriptionally activated by APRF/STAT-3 and other cytokine-inducible nuclear proteins. Mol. Cell. Biol. 16:3490-3503.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 3490-3503
    • Schumann, R.R.1    Kirschning, C.J.2    Unbehaun, A.3    Aherle, H.4    Knopf, H.-P.5    Lamping, N.6    Ulevitch, R.J.7    Herrmann, F.8
  • 25
    • 0027982538 scopus 로고
    • Relative concentrations of endotoxin-binding proteins in body fluids during infection
    • Opal, S.M., J.E. Palardy, M.N. Marra, C.J. Fisher, Jr., B.M. McKelligon, and R.W. Scott. 1994. Relative concentrations of endotoxin-binding proteins in body fluids during infection. Lancet. 344:429-431.
    • (1994) Lancet , vol.344 , pp. 429-431
    • Opal, S.M.1    Palardy, J.E.2    Marra, M.N.3    Fisher Jr., C.J.4    McKelligon, B.M.5    Scott, R.W.6
  • 26
    • 0031304006 scopus 로고    scopus 로고
    • Lipopolysaccharide binding protein: A marker for intraperitoneal bacterial infection in patients with CAPD peritonitis
    • Schäfer, K., R.R. Schumann, S. Stöteknuel, J. Bohler, J. Schollmeyer, and G.J. Dobos. 1997. Lipopolysaccharide binding protein: a marker for intraperitoneal bacterial infection in patients with CAPD peritonitis. Adv. Perit. Dial. 13:210-213.
    • (1997) Adv. Perit. Dial. , vol.13 , pp. 210-213
    • Schäfer, K.1    Schumann, R.R.2    Stöteknuel, S.3    Bohler, J.4    Schollmeyer, J.5    Dobos, G.J.6
  • 27
    • 0028899305 scopus 로고
    • Lipopolysaccharide (LPS) signal transduction and clearance. Dual roles for LPS binding protein and membrane CD14
    • Gegner, J.A., R.J. Ulevitch, and P.S. Tobias. 1995. Lipopolysaccharide (LPS) signal transduction and clearance. Dual roles for LPS binding protein and membrane CD14. J. Biol. Chem. 270:5320-5325.
    • (1995) J. Biol. Chem. , vol.270 , pp. 5320-5325
    • Gegner, J.A.1    Ulevitch, R.J.2    Tobias, P.S.3
  • 30
    • 0018547419 scopus 로고
    • New function for high density lipoproteins: Their participation in intravascular reactions of bacterial lipopolysaccharides (LPS)
    • Ulevitch, R.J., A.R. Johnston, and D.B. Weinstein. 1979. New function for high density lipoproteins: their participation in intravascular reactions of bacterial lipopolysaccharides (LPS). J. Clin. Invest. 64:1516-1524.
    • (1979) J. Clin. Invest. , vol.64 , pp. 1516-1524
    • Ulevitch, R.J.1    Johnston, A.R.2    Weinstein, D.B.3
  • 35
    • 0019752371 scopus 로고
    • Assay of coagulation proteases using peptide chromogenic and fluorogenic substrates
    • Lottenberg, R., U. Christensen, C.M. Jackson, and P.L. Coleman. 1981. Assay of coagulation proteases using peptide chromogenic and fluorogenic substrates. Methods Enzymol. 80:342-361.
    • (1981) Methods Enzymol. , vol.80 , pp. 342-361
    • Lottenberg, R.1    Christensen, U.2    Jackson, C.M.3    Coleman, P.L.4
  • 36
    • 0028577721 scopus 로고
    • Beneficial effects and improved survival rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase
    • Szabó, C., G.J. Southan, and C. Thiemermann. 1994. Beneficial effects and improved survival rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase. Proc. Natl. Acad. Sci. USA. 91:12472-12476.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12472-12476
    • Szabó, C.1    Southan, G.J.2    Thiemermann, C.3
  • 37
    • 0021836738 scopus 로고
    • Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells
    • Beutler, B., J. Mahoney, T.N. Le, P. Pekala, and A. Cerami. 1985. Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells. J. Exp. Med. 161:984-995.
    • (1985) J. Exp. Med. , vol.161 , pp. 984-995
    • Beutler, B.1    Mahoney, J.2    Le, T.N.3    Pekala, P.4    Cerami, A.5
  • 38
    • 0000352873 scopus 로고
    • Galactosamine-induced sensitization to the lethal effects of endotoxin
    • Galanos, C., M.A. Freudenberg, and W. Reutter. 1979. Galactosamine-induced sensitization to the lethal effects of endotoxin. Proc. Natl. Acad. Sci. USA. 76:5939-5943.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 5939-5943
    • Galanos, C.1    Freudenberg, M.A.2    Reutter, W.3
  • 39
    • 0023175468 scopus 로고
    • Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamine-treated mice
    • Lehmann, V., M.A. Freudenberg, and C. Galanos. 1987. Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamine-treated mice. J. Exp. Med. 165:657-663.
    • (1987) J. Exp. Med. , vol.165 , pp. 657-663
    • Lehmann, V.1    Freudenberg, M.A.2    Galanos, C.3
  • 40
    • 0027379689 scopus 로고
    • Lipopolysaccharide-binding protein as a major plasma protein responsible for endotoxemic shock
    • Gallay, P., D. Heumann, D. Le Roy, C. Barras, and M.P. Glauser. 1993. Lipopolysaccharide-binding protein as a major plasma protein responsible for endotoxemic shock. Proc. Natl. Acad. Sci. USA. 90:9935-9938.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9935-9938
    • Gallay, P.1    Heumann, D.2    Le Roy, D.3    Barras, C.4    Glauser, M.P.5
  • 41
    • 0028108442 scopus 로고
    • Mode of action of anti-lipopolysaccharide binding protein antibodies for prevention of endotoxemic shock in mice
    • Gallay, P., D. Heumann, D. Le Roy, C. Barras, and M.P. Glauser. 1994. Mode of action of anti-lipopolysaccharide binding protein antibodies for prevention of endotoxemic shock in mice. Proc. Natl. Acad. Sci. USA. 91:7922-7926.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 7922-7926
    • Gallay, P.1    Heumann, D.2    Le Roy, D.3    Barras, C.4    Glauser, M.P.5
  • 43
    • 0029919991 scopus 로고    scopus 로고
    • Resistance to endotoxin shock and reduced dissemination of gram negative bacteria in CD14 deficient mice
    • Haziot, A., E. Ferrero, F. Kontgen, N. Hijiya, S. Yamamoto, J. Silver, C.L. Stewart, and S.M. Goyert. 1996. Resistance to endotoxin shock and reduced dissemination of gram negative bacteria in CD14 deficient mice. Immunity. 4:407-414.
    • (1996) Immunity , vol.4 , pp. 407-414
    • Haziot, A.1    Ferrero, E.2    Kontgen, F.3    Hijiya, N.4    Yamamoto, S.5    Silver, J.6    Stewart, C.L.7    Goyert, S.M.8
  • 45
    • 0029057595 scopus 로고
    • Recombinant soluble CD14 prevents mortality in mice treated with endotoxin (lipopolysaccharide)
    • Haziot, A., G.W. Rong, X.Y. Lin, J. Silver, and S.M. Goyert. 1995. Recombinant soluble CD14 prevents mortality in mice treated with endotoxin (lipopolysaccharide). J. Immunol. 154:6529-6532.
    • (1995) J. Immunol. , vol.154 , pp. 6529-6532
    • Haziot, A.1    Rong, G.W.2    Lin, X.Y.3    Silver, J.4    Goyert, S.M.5
  • 46
    • 15644383706 scopus 로고    scopus 로고
    • Biochemical characterization of recombinant fusions of lipopolysaccharide binding protein and bactericidal/permeability increasing protein: Implications in biological activity
    • Abrahamson, S.L., H.M. Wu, R.E. Williams, K. Der, N. Ottah, R. Little, H. Gazzano-Santoro, G. Theofan, R. Bauer, S. Leigh, et al. 1997. Biochemical characterization of recombinant fusions of lipopolysaccharide binding protein and bactericidal/permeability increasing protein: implications in biological activity. J. Biol. Chem. 272:2149-2155.
    • (1997) J. Biol. Chem. , vol.272 , pp. 2149-2155
    • Abrahamson, S.L.1    Wu, H.M.2    Williams, R.E.3    Der, K.4    Ottah, N.5    Little, R.6    Gazzano-Santoro, H.7    Theofan, G.8    Bauer, R.9    Leigh, S.10
  • 47
    • 0031573234 scopus 로고    scopus 로고
    • Two functionally independent pathways for lipopolysaccharide-dependent activation of mouse peritoneal macrophages
    • Amura, C.R., L.-C. Chen, N. Hirohashi, M.-G. Lei, and D.C. Morrison. 1997. Two functionally independent pathways for lipopolysaccharide-dependent activation of mouse peritoneal macrophages. J. Immunol. 159:5079-5083.
    • (1997) J. Immunol. , vol.159 , pp. 5079-5083
    • Amura, C.R.1    Chen, L.-C.2    Hirohashi, N.3    Lei, M.-G.4    Morrison, D.C.5
  • 49
    • 0030855108 scopus 로고    scopus 로고
    • Lipopolysaccharide (LPS) binding proteins BPI and LBP form different types of complexes with LPS
    • Tobias, P.S., K. Soldau, N.M. Iovine, P. Elsbach, and J. Weiss. 1997. Lipopolysaccharide (LPS) binding proteins BPI and LBP form different types of complexes with LPS. J. Biol. Chem. 272:18682-18685.
    • (1997) J. Biol. Chem. , vol.272 , pp. 18682-18685
    • Tobias, P.S.1    Soldau, K.2    Iovine, N.M.3    Elsbach, P.4    Weiss, J.5
  • 50
    • 0030897425 scopus 로고    scopus 로고
    • Structural determinants for the interaction of lipopolysaccharide binding protein with purified high density lipoproteins: Role ol apolipoprotein A-I
    • Massamiri, T., P.S. Tobias, and L.K. Curtiss. 1997. Structural determinants for the interaction of lipopolysaccharide binding protein with purified high density lipoproteins: role ol apolipoprotein A-I. J. Lipid. Res. 38:516-525.
    • (1997) J. Lipid. Res. , vol.38 , pp. 516-525
    • Massamiri, T.1    Tobias, P.S.2    Curtiss, L.K.3
  • 51
    • 0009532080 scopus 로고    scopus 로고
    • Plasma levels of lipopolysaccharide binding protein (LBP) correlate with outcome in sepsis and other patients
    • Abstr.
    • Carroll, S.F., R.L. Dedrick, and M.L. White. 1997. Plasma levels of lipopolysaccharide binding protein (LBP) correlate with outcome in sepsis and other patients. Shock. 8:101. (Abstr.)
    • (1997) Shock , vol.8 , pp. 101
    • Carroll, S.F.1    Dedrick, R.L.2    White, M.L.3


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