Targeted deletion of the lipopolysaccharide (LPS)-binding protein gene leads to profound suppression of LPS responses ex vivo, whereas in vivo responses remain intact

Journal of Experimental Medicine

Volumn 186, Issue 12, 1997, Pages 2051-2056

  Wurfel, Mark M ^a   Monks, Brian G ^b,c   Ingalls, Robin R ^b,c   Dedrick, Russell L ^d   Delude, Russell ^b,c   Zhou, Dahua ^a   Lamping, Norbert ^f   Schumann, Ralf R ^f   Thieringer, Rolf ^e   Fenton, Matthew J ^c   Wright, Samuel D ^a,e   Golenbock, Douglas ^b,c  

^a ROCKEFELLER UNIVERSITY   (United States)

^b Maxwell Finland Lab Infect Dis   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d XOMA Corporation   (United States)

^e MERCK RESEARCH LABORATORIES   (United States)

^f CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; LIPID BINDING PROTEIN;

ARTICLE; EMBRYO; EXPRESSION VECTOR; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GENE TARGETING; GRAM NEGATIVE INFECTION; HOMOZYGOSITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0031440937     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.186.12.2051     Document Type: Article

References (22)

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